locus-tag	class	description
SynNOUM97013_RS00005	COG0592	DNA-directed DNA polymerase activity
SynNOUM97013_RS00015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynNOUM97013_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynNOUM97013_RS00035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynNOUM97013_RS00050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynNOUM97013_RS00055	COG0552	protein localization to endoplasmic reticulum
SynNOUM97013_RS00060	COG2208	phosphoserine phosphatase activity
SynNOUM97013_RS00065	COG0165	Argininosuccinate lyase
SynNOUM97013_RS00070	COG0724	RNA recognition motif
SynNOUM97013_RS00075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynNOUM97013_RS00085	COG2081	HI0933 family
SynNOUM97013_RS00090	COG1459	type II secretion system
SynNOUM97013_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynNOUM97013_RS00105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynNOUM97013_RS00110	COG0484	heat shock protein binding
SynNOUM97013_RS00120	COG1162	GTPase activity
SynNOUM97013_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynNOUM97013_RS00130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynNOUM97013_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynNOUM97013_RS00140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynNOUM97013_RS00145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynNOUM97013_RS00150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynNOUM97013_RS00155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynNOUM97013_RS00160	COG0511	ligase activity, forming carbon-carbon bonds
SynNOUM97013_RS00165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynNOUM97013_RS00235	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynNOUM97013_RS00240	COG0519	Catalyzes the synthesis of GMP from XMP
SynNOUM97013_RS00240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynNOUM97013_RS00260	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynNOUM97013_RS00275	COG2022	thiamine diphosphate biosynthetic process
SynNOUM97013_RS00290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynNOUM97013_RS00295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynNOUM97013_RS00300	COG2385	sporulation resulting in formation of a cellular spore
SynNOUM97013_RS00305	COG1215	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynNOUM97013_RS00320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynNOUM97013_RS00325	COG0740	serine-type endopeptidase activity
SynNOUM97013_RS00330	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynNOUM97013_RS00335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynNOUM97013_RS00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynNOUM97013_RS00345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynNOUM97013_RS00355	COG0037	tRNA processing
SynNOUM97013_RS00370	COG0556	nucleotide-excision repair
SynNOUM97013_RS00375	COG0527	aspartate kinase activity
SynNOUM97013_RS00385	COG2082	Precorrin-8x methylmutase
SynNOUM97013_RS00395	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynNOUM97013_RS00410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynNOUM97013_RS00420	COG0653	protein targeting
SynNOUM97013_RS00425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynNOUM97013_RS00500	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00500	COG1216	Glycosyl transferase, family 2
SynNOUM97013_RS00525	COG2192	nodulation
SynNOUM97013_RS00540	COG1045	serine acetyltransferase
SynNOUM97013_RS00545	COG1725	Transcriptional regulator
SynNOUM97013_RS00555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynNOUM97013_RS00560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynNOUM97013_RS00565	COG0187	DNA topoisomerase II activity
SynNOUM97013_RS00565	COG1372	Participates in initiation and elongation during chromosome replication
SynNOUM97013_RS00575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynNOUM97013_RS00580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynNOUM97013_RS00585	COG0386	Belongs to the glutathione peroxidase family
SynNOUM97013_RS00595	COG2239	Acts as a magnesium transporter
SynNOUM97013_RS00600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS00610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynNOUM97013_RS00635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynNOUM97013_RS00640	COG0802	atpase or kinase
SynNOUM97013_RS00645	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynNOUM97013_RS00660	COG0586	Pfam SNARE associated Golgi protein
SynNOUM97013_RS00665	COG0629	single-stranded DNA binding
SynNOUM97013_RS00675	COG1792	Involved in formation and maintenance of cell shape
SynNOUM97013_RS00695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynNOUM97013_RS00715	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynNOUM97013_RS00720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynNOUM97013_RS00725	COG0515	serine threonine protein kinase
SynNOUM97013_RS00730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynNOUM97013_RS00735	COG2255	four-way junction helicase activity
SynNOUM97013_RS00745	COG1473	amidohydrolase
SynNOUM97013_RS00760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynNOUM97013_RS00770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynNOUM97013_RS00775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynNOUM97013_RS00780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynNOUM97013_RS00785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS00790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynNOUM97013_RS00795	COG1088	dTDP-glucose 4,6-dehydratase activity
SynNOUM97013_RS00800	COG0662	Cupin 2, conserved barrel domain protein
SynNOUM97013_RS00800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynNOUM97013_RS00810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynNOUM97013_RS00815	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynNOUM97013_RS00820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynNOUM97013_RS00830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynNOUM97013_RS00835	COG0571	ribonuclease III activity
SynNOUM97013_RS00865	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SynNOUM97013_RS00870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SynNOUM97013_RS00875	COG0058	SHG alpha-glucan phosphorylase activity
SynNOUM97013_RS00880	COG0475	glutathione-regulated potassium exporter activity
SynNOUM97013_RS00900	COG0277	FAD linked oxidase domain protein
SynNOUM97013_RS00910	COG0247	lactate metabolic process
SynNOUM97013_RS00920	COG0538	isocitrate dehydrogenase activity
SynNOUM97013_RS00925	COG0463	Glycosyl transferase, family 2
SynNOUM97013_RS00935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SynNOUM97013_RS00945	COG5398	heme oxygenase
SynNOUM97013_RS00960	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00965	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS00975	COG0297	glycogen (starch) synthase activity
SynNOUM97013_RS00985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynNOUM97013_RS00995	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynNOUM97013_RS01005	COG1215	transferase activity, transferring glycosyl groups
SynNOUM97013_RS01015	COG0617	tRNA 3'-terminal CCA addition
SynNOUM97013_RS01020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynNOUM97013_RS01025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SynNOUM97013_RS01025	COG0517	IMP dehydrogenase activity
SynNOUM97013_RS01040	COG0709	Synthesizes selenophosphate from selenide and ATP
SynNOUM97013_RS01045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynNOUM97013_RS01050	COG0124	histidyl-tRNA synthetase
SynNOUM97013_RS01070	COG1596	polysaccharide export
SynNOUM97013_RS01080	COG1132	(ABC) transporter
SynNOUM97013_RS01085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynNOUM97013_RS01095	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SynNOUM97013_RS01135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynNOUM97013_RS01145	COG2089	acid synthase
SynNOUM97013_RS01160	COG0107	imidazoleglycerol-phosphate synthase activity
SynNOUM97013_RS01170	COG1083	cytidylyl-transferase
SynNOUM97013_RS01185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynNOUM97013_RS01190	COG2089	acid synthase
SynNOUM97013_RS01195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynNOUM97013_RS01235	COG0110	maltose O-acetyltransferase activity
SynNOUM97013_RS01275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynNOUM97013_RS01310	COG4447	cellulose binding
SynNOUM97013_RS01315	COG1773	rubredoxin
SynNOUM97013_RS01320	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS01325	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS01330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS01335	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynNOUM97013_RS01340	COG3842	ATPase activity
SynNOUM97013_RS01345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SynNOUM97013_RS01350	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynNOUM97013_RS01350	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynNOUM97013_RS01360	COG1132	(ABC) transporter
SynNOUM97013_RS01365	COG0494	nUDIX hydrolase
SynNOUM97013_RS01370	COG0415	Belongs to the DNA photolyase family
SynNOUM97013_RS01400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynNOUM97013_RS01405	COG0131	Imidazoleglycerol-phosphate dehydratase
SynNOUM97013_RS01410	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynNOUM97013_RS01420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynNOUM97013_RS01440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynNOUM97013_RS01445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynNOUM97013_RS01460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynNOUM97013_RS01475	COG1253	flavin adenine dinucleotide binding
SynNOUM97013_RS01480	COG0673	inositol 2-dehydrogenase activity
SynNOUM97013_RS01490	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SynNOUM97013_RS01500	COG0343	queuine tRNA-ribosyltransferase activity
SynNOUM97013_RS01505	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynNOUM97013_RS01525	COG0138	bifunctional purine biosynthesis protein purh
SynNOUM97013_RS01545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynNOUM97013_RS01550	COG0004	ammonium transporteR
SynNOUM97013_RS01555	COG1489	DNA binding
SynNOUM97013_RS01560	COG0728	peptidoglycan biosynthetic process
SynNOUM97013_RS01585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynNOUM97013_RS01590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynNOUM97013_RS01595	COG1546	Belongs to the CinA family
SynNOUM97013_RS01595	COG1058	Belongs to the CinA family
SynNOUM97013_RS01600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynNOUM97013_RS01605	COG0066	3-isopropylmalate dehydratase activity
SynNOUM97013_RS01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynNOUM97013_RS01645	COG0193	aminoacyl-tRNA hydrolase activity
SynNOUM97013_RS01660	COG4372	Transposase
SynNOUM97013_RS01665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynNOUM97013_RS01670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynNOUM97013_RS01680	COG0717	Belongs to the dCTP deaminase family
SynNOUM97013_RS01690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynNOUM97013_RS01710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynNOUM97013_RS01725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynNOUM97013_RS01745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynNOUM97013_RS01765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynNOUM97013_RS01780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynNOUM97013_RS01790	COG2094	Belongs to the DNA glycosylase MPG family
SynNOUM97013_RS01795	COG0540	Belongs to the ATCase OTCase family
SynNOUM97013_RS01820	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynNOUM97013_RS01830	COG3536	Protein conserved in bacteria
SynNOUM97013_RS01835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynNOUM97013_RS01850	COG2046	Belongs to the sulfate adenylyltransferase family
SynNOUM97013_RS01850	COG0529	Catalyzes the synthesis of activated sulfate
SynNOUM97013_RS01855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynNOUM97013_RS01870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynNOUM97013_RS01880	COG0385	Bile acid
SynNOUM97013_RS01910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynNOUM97013_RS01915	COG0436	Aminotransferase
SynNOUM97013_RS01925	COG1530	ribonuclease E activity
SynNOUM97013_RS01930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynNOUM97013_RS01940	COG0077	Prephenate dehydratase
SynNOUM97013_RS01945	COG2226	methyltransferase
SynNOUM97013_RS01950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynNOUM97013_RS01955	COG0051	transcription antitermination factor activity, RNA binding
SynNOUM97013_RS01960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynNOUM97013_RS01965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynNOUM97013_RS01970	COG0049	tRNA binding
SynNOUM97013_RS01975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynNOUM97013_RS01990	COG0067	glutamate synthase
SynNOUM97013_RS01990	COG0069	glutamate synthase activity
SynNOUM97013_RS01990	COG0070	glutamate synthase
SynNOUM97013_RS02000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynNOUM97013_RS02020	COG2885	chlorophyll binding
SynNOUM97013_RS02025	COG2885	chlorophyll binding
SynNOUM97013_RS02060	COG0463	Glycosyl transferase, family 2
SynNOUM97013_RS02080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynNOUM97013_RS02090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynNOUM97013_RS02100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynNOUM97013_RS02105	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynNOUM97013_RS02110	COG0101	tRNA pseudouridine synthase activity
SynNOUM97013_RS02115	COG0203	ribosomal protein L17
SynNOUM97013_RS02120	COG0202	RNA polymerase activity
SynNOUM97013_RS02125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynNOUM97013_RS02130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynNOUM97013_RS02135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynNOUM97013_RS02140	COG0563	adenylate kinase activity
SynNOUM97013_RS02145	COG0201	protein transport
SynNOUM97013_RS02150	COG0200	Binds to the 23S rRNA
SynNOUM97013_RS02155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynNOUM97013_RS02160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynNOUM97013_RS02165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynNOUM97013_RS02170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynNOUM97013_RS02175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynNOUM97013_RS02180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynNOUM97013_RS02185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynNOUM97013_RS02190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynNOUM97013_RS02195	COG0255	Belongs to the universal ribosomal protein uL29 family
SynNOUM97013_RS02200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynNOUM97013_RS02205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynNOUM97013_RS02210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynNOUM97013_RS02215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynNOUM97013_RS02220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynNOUM97013_RS02225	COG0089	rRNA binding
SynNOUM97013_RS02230	COG0088	Forms part of the polypeptide exit tunnel
SynNOUM97013_RS02235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynNOUM97013_RS02250	COG3854	ATPases associated with a variety of cellular activities
SynNOUM97013_RS02265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynNOUM97013_RS02285	COG0287	Prephenate dehydrogenase
SynNOUM97013_RS02290	COG1233	COG1233 Phytoene dehydrogenase and related
SynNOUM97013_RS02295	COG3001	Fructosamine kinase
SynNOUM97013_RS02315	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynNOUM97013_RS02320	COG1606	tRNA processing
SynNOUM97013_RS02325	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynNOUM97013_RS02330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynNOUM97013_RS02345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynNOUM97013_RS02355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynNOUM97013_RS02370	COG0772	Belongs to the SEDS family
SynNOUM97013_RS02375	COG0489	protein tyrosine kinase activity
SynNOUM97013_RS02380	COG0408	coproporphyrinogen oxidase activity
SynNOUM97013_RS02435	COG0667	Aldo Keto reductase
SynNOUM97013_RS02445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynNOUM97013_RS02450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynNOUM97013_RS02455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynNOUM97013_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynNOUM97013_RS02460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynNOUM97013_RS02610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynNOUM97013_RS02650	COG1070	Carbohydrate kinase
SynNOUM97013_RS02655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynNOUM97013_RS02665	COG0539	negative regulation of cytoplasmic translation
SynNOUM97013_RS02670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynNOUM97013_RS02705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynNOUM97013_RS02705	COG0758	DNA mediated transformation
SynNOUM97013_RS02710	COG2890	protein-(glutamine-N5) methyltransferase activity
SynNOUM97013_RS02715	COG0009	L-threonylcarbamoyladenylate synthase
SynNOUM97013_RS02735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynNOUM97013_RS02740	COG2894	cell division
SynNOUM97013_RS02745	COG0850	regulation of cytokinetic process
SynNOUM97013_RS02750	COG1078	dGTPase activity
SynNOUM97013_RS02755	COG0793	Belongs to the peptidase S41A family
SynNOUM97013_RS02760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynNOUM97013_RS02765	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynNOUM97013_RS02800	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynNOUM97013_RS02805	COG0235	Class ii aldolase
SynNOUM97013_RS02810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynNOUM97013_RS02830	COG3942	CHAP domain
SynNOUM97013_RS02830	COG1388	LysM domain
SynNOUM97013_RS02835	COG1012	belongs to the aldehyde dehydrogenase family
SynNOUM97013_RS02845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynNOUM97013_RS02850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SynNOUM97013_RS02860	COG5000	phosphorelay sensor kinase activity
SynNOUM97013_RS02880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynNOUM97013_RS02900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynNOUM97013_RS02915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynNOUM97013_RS02930	COG1376	ErfK ybiS ycfS ynhG family protein
SynNOUM97013_RS02935	COG1160	GTP binding
SynNOUM97013_RS02940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynNOUM97013_RS02950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynNOUM97013_RS02955	COG1799	cell septum assembly
SynNOUM97013_RS02960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynNOUM97013_RS02965	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS02975	COG1381	Involved in DNA repair and RecF pathway recombination
SynNOUM97013_RS02980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynNOUM97013_RS02985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynNOUM97013_RS02990	COG0321	lipoyl(octanoyl) transferase activity
SynNOUM97013_RS02995	COG1022	Amp-dependent synthetase and ligase
SynNOUM97013_RS03010	COG0531	amino acid
SynNOUM97013_RS03015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynNOUM97013_RS03025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynNOUM97013_RS03035	COG0626	cystathionine gamma-synthase activity
SynNOUM97013_RS03060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynNOUM97013_RS03065	COG1104	cysteine desulfurase activity
SynNOUM97013_RS03085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynNOUM97013_RS03090	COG0579	oxidoreductase
SynNOUM97013_RS03105	COG3119	arylsulfatase activity
SynNOUM97013_RS03115	COG0481	GTPase activity
SynNOUM97013_RS03145	COG4968	Prepilin-type N-terminal cleavage methylation domain
SynNOUM97013_RS03155	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS03180	COG2205	protein histidine kinase activity
SynNOUM97013_RS03190	COG4999	Histidine kinase
SynNOUM97013_RS03190	COG3850	Histidine kinase
SynNOUM97013_RS03190	COG3437	response regulator, receiver
SynNOUM97013_RS03190	COG2205	protein histidine kinase activity
SynNOUM97013_RS03205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynNOUM97013_RS03215	COG3695	enzyme binding
SynNOUM97013_RS03220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynNOUM97013_RS03220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynNOUM97013_RS03225	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynNOUM97013_RS03230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynNOUM97013_RS03240	COG0107	imidazoleglycerol-phosphate synthase activity
SynNOUM97013_RS03250	COG2226	methyltransferase
SynNOUM97013_RS03300	COG0752	glycyl-tRNA synthetase alpha subunit
SynNOUM97013_RS03330	COG2132	Multicopper oxidase
SynNOUM97013_RS03335	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynNOUM97013_RS03370	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynNOUM97013_RS03380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynNOUM97013_RS03385	COG0740	serine-type endopeptidase activity
SynNOUM97013_RS03390	COG0740	serine-type endopeptidase activity
SynNOUM97013_RS03395	COG4956	integral membrane protein (PIN domain superfamily)
SynNOUM97013_RS03400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynNOUM97013_RS03405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynNOUM97013_RS03415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynNOUM97013_RS03430	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynNOUM97013_RS03435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynNOUM97013_RS03440	COG4948	Mandelate Racemase Muconate Lactonizing
SynNOUM97013_RS03470	COG1357	PFAM Pentapeptide repeats (8 copies)
SynNOUM97013_RS03475	COG0285	dihydrofolate synthase activity
SynNOUM97013_RS03480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynNOUM97013_RS03500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynNOUM97013_RS03515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynNOUM97013_RS03520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynNOUM97013_RS03525	COG0134	indole-3-glycerol-phosphate synthase activity
SynNOUM97013_RS03555	COG1007	ATP synthesis coupled electron transport
SynNOUM97013_RS03560	COG1006	Multisubunit Na H antiporter MnhC subunit
SynNOUM97013_RS03585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynNOUM97013_RS03590	COG0482	sulfurtransferase activity
SynNOUM97013_RS03595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynNOUM97013_RS03595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynNOUM97013_RS03600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS03605	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynNOUM97013_RS03610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynNOUM97013_RS03620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynNOUM97013_RS03625	COG0228	four-way junction DNA binding
SynNOUM97013_RS03630	COG1702	phosphate starvation-inducible protein PhoH
SynNOUM97013_RS03635	COG0670	Belongs to the BI1 family
SynNOUM97013_RS03645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynNOUM97013_RS03655	COG0336	Belongs to the RNA methyltransferase TrmD family
SynNOUM97013_RS03660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynNOUM97013_RS03670	COG1691	(AIR) carboxylase
SynNOUM97013_RS03690	COG0352	thiamine-phosphate diphosphorylase activity
SynNOUM97013_RS03695	COG0196	riboflavin kinase activity
SynNOUM97013_RS03705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynNOUM97013_RS03710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynNOUM97013_RS03725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynNOUM97013_RS03780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynNOUM97013_RS03785	COG3119	arylsulfatase activity
SynNOUM97013_RS03845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynNOUM97013_RS03845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynNOUM97013_RS03855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynNOUM97013_RS03860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynNOUM97013_RS03895	COG1647	Serine aminopeptidase, S33
SynNOUM97013_RS03915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynNOUM97013_RS03930	COG2208	phosphoserine phosphatase activity
SynNOUM97013_RS03930	COG2770	Histidine kinase
SynNOUM97013_RS03980	COG0477	Major facilitator Superfamily
SynNOUM97013_RS03985	COG0432	Pfam Uncharacterised protein family UPF0047
SynNOUM97013_RS04010	COG1492	cobalamin metabolic process
SynNOUM97013_RS04025	COG2274	protein secretion by the type I secretion system
SynNOUM97013_RS04045	COG0424	maF-like protein
SynNOUM97013_RS04085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynNOUM97013_RS04090	COG0440	acetolactate synthase activity
SynNOUM97013_RS04110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynNOUM97013_RS04120	COG2226	methyltransferase
SynNOUM97013_RS04125	COG1187	pseudouridine synthase activity
SynNOUM97013_RS04135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynNOUM97013_RS04140	COG0492	ferredoxin-NADP+ reductase activity
SynNOUM97013_RS04185	COG3411	Ferredoxin
SynNOUM97013_RS04190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynNOUM97013_RS04195	COG0733	neurotransmitter:sodium symporter activity
SynNOUM97013_RS04210	COG0215	cysteine-tRNA ligase activity
SynNOUM97013_RS04215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynNOUM97013_RS04215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynNOUM97013_RS04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynNOUM97013_RS04225	COG0012	GTP binding
SynNOUM97013_RS04250	COG0601	transmembrane transport
SynNOUM97013_RS04255	COG0747	negative chemotaxis
SynNOUM97013_RS04265	COG0460	homoserine dehydrogenase
SynNOUM97013_RS04270	COG2166	iron-sulfur cluster assembly
SynNOUM97013_RS04280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynNOUM97013_RS04295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynNOUM97013_RS04300	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynNOUM97013_RS04320	COG2010	Cytochrome c
SynNOUM97013_RS04330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynNOUM97013_RS04335	COG3118	belongs to the thioredoxin family
SynNOUM97013_RS04340	COG0516	GMP reductase activity
SynNOUM97013_RS04350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynNOUM97013_RS04355	COG0644	oxidoreductase
SynNOUM97013_RS04365	COG1543	Belongs to the glycosyl hydrolase 57 family
SynNOUM97013_RS04370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynNOUM97013_RS04375	COG0395	ABC-type sugar transport system, permease component
SynNOUM97013_RS04395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynNOUM97013_RS04415	COG0011	TIGRFAM Protein of
SynNOUM97013_RS04435	COG0564	pseudouridine synthase activity
SynNOUM97013_RS04440	COG1480	7TM receptor with intracellular HD hydrolase
SynNOUM97013_RS04445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynNOUM97013_RS04470	COG1254	Belongs to the acylphosphatase family
SynNOUM97013_RS04475	COG1797	cobyrinic acid a,c-diamide synthase activity
SynNOUM97013_RS04480	COG3409	Peptidoglycan-binding domain 1 protein
SynNOUM97013_RS04480	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynNOUM97013_RS04485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynNOUM97013_RS04490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynNOUM97013_RS04505	COG2205	protein histidine kinase activity
SynNOUM97013_RS04520	COG0308	aminopeptidase N
SynNOUM97013_RS04550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynNOUM97013_RS04565	COG0702	epimerase
SynNOUM97013_RS04570	COG1640	4-alpha-glucanotransferase
SynNOUM97013_RS04580	COG1187	pseudouridine synthase activity
SynNOUM97013_RS04585	COG5002	protein histidine kinase activity
SynNOUM97013_RS04590	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS04595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS04605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynNOUM97013_RS04615	COG0575	Belongs to the CDS family
SynNOUM97013_RS04640	COG0575	Belongs to the CDS family
SynNOUM97013_RS04650	COG2267	carboxylic ester hydrolase activity
SynNOUM97013_RS04655	COG0371	Dehydrogenase
SynNOUM97013_RS04660	COG0542	response to heat
SynNOUM97013_RS04670	COG0019	diaminopimelate decarboxylase activity
SynNOUM97013_RS04675	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynNOUM97013_RS04680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynNOUM97013_RS04685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynNOUM97013_RS04690	COG1054	Belongs to the UPF0176 family
SynNOUM97013_RS04705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynNOUM97013_RS04710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynNOUM97013_RS04750	COG0475	glutathione-regulated potassium exporter activity
SynNOUM97013_RS04750	COG0589	response to stress
SynNOUM97013_RS04755	COG1132	(ABC) transporter
SynNOUM97013_RS04765	COG0724	RNA recognition motif
SynNOUM97013_RS04775	COG0513	Belongs to the DEAD box helicase family
SynNOUM97013_RS04785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynNOUM97013_RS04790	COG1074	ATP-dependent DNA helicase activity
SynNOUM97013_RS04795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynNOUM97013_RS04800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SynNOUM97013_RS04850	COG4106	trans-aconitate 2-methyltransferase activity
SynNOUM97013_RS04855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynNOUM97013_RS04880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynNOUM97013_RS04885	COG1122	ATPase activity
SynNOUM97013_RS04915	COG1836	PFAM Integral membrane protein DUF92
SynNOUM97013_RS04920	COG1191	sigma factor activity
SynNOUM97013_RS04935	COG2720	vancomycin resistance protein
SynNOUM97013_RS04980	COG0300	oxidoreductase activity
SynNOUM97013_RS05055	COG2032	superoxide dismutase activity
SynNOUM97013_RS05125	COG1121	(ABC) transporter
SynNOUM97013_RS05130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynNOUM97013_RS05145	COG2010	Cytochrome c
SynNOUM97013_RS05150	COG0701	Predicted permease
SynNOUM97013_RS05165	COG1121	(ABC) transporter
SynNOUM97013_RS05170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynNOUM97013_RS05175	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynNOUM97013_RS05280	COG3961	Belongs to the TPP enzyme family
SynNOUM97013_RS05295	COG1136	(ABC) transporter
SynNOUM97013_RS05325	COG0681	Belongs to the peptidase S26 family
SynNOUM97013_RS05330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynNOUM97013_RS05335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SynNOUM97013_RS05340	COG1376	ErfK ybiS ycfS ynhG family protein
SynNOUM97013_RS05345	COG0297	glycogen (starch) synthase activity
SynNOUM97013_RS05355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynNOUM97013_RS05370	COG1597	lipid kinase activity
SynNOUM97013_RS05370	COG1803	Methylglyoxal synthase
SynNOUM97013_RS05375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynNOUM97013_RS05385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynNOUM97013_RS05450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynNOUM97013_RS05455	COG3659	wide pore channel activity
SynNOUM97013_RS05465	COG3128	pkhd-type hydroxylase
SynNOUM97013_RS05470	COG1840	ABC-type Fe3 transport system, periplasmic component
SynNOUM97013_RS05475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynNOUM97013_RS05480	COG2045	Belongs to the ComB family
SynNOUM97013_RS05495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynNOUM97013_RS05500	COG0142	geranyltranstransferase activity
SynNOUM97013_RS05505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynNOUM97013_RS05515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynNOUM97013_RS05525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynNOUM97013_RS05530	COG2176	DNA-directed DNA polymerase activity
SynNOUM97013_RS05545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynNOUM97013_RS05565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynNOUM97013_RS05580	COG1132	(ABC) transporter
SynNOUM97013_RS05585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynNOUM97013_RS05590	COG0505	Belongs to the CarA family
SynNOUM97013_RS05600	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynNOUM97013_RS05605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynNOUM97013_RS05615	COG0154	amidase activity
SynNOUM97013_RS05620	COG0587	DNA-directed DNA polymerase activity
SynNOUM97013_RS05630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynNOUM97013_RS05635	COG0632	four-way junction helicase activity
SynNOUM97013_RS05655	COG0358	DNA primase activity
SynNOUM97013_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
SynNOUM97013_RS05695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynNOUM97013_RS05720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynNOUM97013_RS05750	COG0572	uridine kinase
SynNOUM97013_RS05755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynNOUM97013_RS05760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynNOUM97013_RS05770	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynNOUM97013_RS05770	COG0022	dehydrogenase e1 component
SynNOUM97013_RS05775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynNOUM97013_RS05780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynNOUM97013_RS05805	COG0628	permease
SynNOUM97013_RS05815	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynNOUM97013_RS05820	COG0515	serine threonine protein kinase
SynNOUM97013_RS05840	COG2226	methyltransferase
SynNOUM97013_RS05855	COG0174	glutamine synthetase
SynNOUM97013_RS05865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynNOUM97013_RS05885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynNOUM97013_RS05890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynNOUM97013_RS05910	COG0612	Peptidase, M16
SynNOUM97013_RS05940	COG1216	Glycosyl transferase, family 2
SynNOUM97013_RS05945	COG0052	Belongs to the universal ribosomal protein uS2 family
SynNOUM97013_RS05950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynNOUM97013_RS05960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynNOUM97013_RS05965	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynNOUM97013_RS05970	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynNOUM97013_RS05975	COG0751	glycine-tRNA ligase activity
SynNOUM97013_RS05980	COG0644	oxidoreductase
SynNOUM97013_RS05990	COG0826	peptidase U32
SynNOUM97013_RS05995	COG1217	gtp-binding protein TYPA
SynNOUM97013_RS06020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynNOUM97013_RS06085	COG0420	3'-5' exonuclease activity
SynNOUM97013_RS06100	COG0625	glutathione transferase activity
SynNOUM97013_RS06115	COG1799	cell septum assembly
SynNOUM97013_RS06125	COG0735	belongs to the Fur family
SynNOUM97013_RS06160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynNOUM97013_RS06175	COG0271	Belongs to the BolA IbaG family
SynNOUM97013_RS06180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynNOUM97013_RS06185	COG0596	Alpha beta hydrolase
SynNOUM97013_RS06195	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS06225	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynNOUM97013_RS06250	COG5002	protein histidine kinase activity
SynNOUM97013_RS06270	COG0861	Integral membrane protein TerC family
SynNOUM97013_RS06285	COG0513	Belongs to the DEAD box helicase family
SynNOUM97013_RS06290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynNOUM97013_RS06305	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynNOUM97013_RS06320	COG0163	prenyltransferase activity
SynNOUM97013_RS06325	COG0557	exoribonuclease II activity
SynNOUM97013_RS06335	COG2119	membrane
SynNOUM97013_RS06355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynNOUM97013_RS06355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynNOUM97013_RS06360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynNOUM97013_RS06375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynNOUM97013_RS06380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynNOUM97013_RS06385	COG1615	UPF0182 protein
SynNOUM97013_RS06390	COG0450	alkyl hydroperoxide reductase
SynNOUM97013_RS06405	COG0739	heme binding
SynNOUM97013_RS06410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynNOUM97013_RS06445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynNOUM97013_RS06455	COG0557	exoribonuclease II activity
SynNOUM97013_RS06460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynNOUM97013_RS06465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynNOUM97013_RS06470	COG0072	phenylalanine-tRNA ligase activity
SynNOUM97013_RS06475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynNOUM97013_RS06500	COG1191	sigma factor activity
SynNOUM97013_RS06510	COG2385	sporulation resulting in formation of a cellular spore
SynNOUM97013_RS06535	COG0646	methionine synthase
SynNOUM97013_RS06535	COG1410	methionine synthase
SynNOUM97013_RS06540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynNOUM97013_RS06560	COG1981	membrane
SynNOUM97013_RS06565	COG3046	protein related to deoxyribodipyrimidine photolyase
SynNOUM97013_RS06575	COG0322	excinuclease ABC activity
SynNOUM97013_RS06580	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynNOUM97013_RS06605	COG1104	cysteine desulfurase activity
SynNOUM97013_RS06610	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynNOUM97013_RS06620	COG0495	leucyl-tRNA aminoacylation
SynNOUM97013_RS06625	COG0166	Belongs to the GPI family
SynNOUM97013_RS06650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynNOUM97013_RS06655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynNOUM97013_RS06660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynNOUM97013_RS06660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynNOUM97013_RS06665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynNOUM97013_RS06670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynNOUM97013_RS06675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynNOUM97013_RS06685	COG0484	heat shock protein binding
SynNOUM97013_RS06690	COG0443	Heat shock 70 kDa protein
SynNOUM97013_RS06695	COG0573	inorganic phosphate transmembrane transporter activity
SynNOUM97013_RS06700	COG0581	inorganic phosphate transmembrane transporter activity
SynNOUM97013_RS06705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynNOUM97013_RS06720	COG0483	inositol monophosphate 1-phosphatase activity
SynNOUM97013_RS06725	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynNOUM97013_RS06735	COG0326	Molecular chaperone. Has ATPase activity
SynNOUM97013_RS06740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynNOUM97013_RS06745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynNOUM97013_RS06750	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynNOUM97013_RS06755	COG1653	transport
SynNOUM97013_RS06795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynNOUM97013_RS06800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynNOUM97013_RS06820	COG0469	pyruvate kinase activity
SynNOUM97013_RS06825	COG1136	(ABC) transporter
SynNOUM97013_RS06825	COG0577	efflux transmembrane transporter activity
SynNOUM97013_RS06830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynNOUM97013_RS06835	COG0740	serine-type endopeptidase activity
SynNOUM97013_RS06860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynNOUM97013_RS06915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynNOUM97013_RS06920	COG1175	transmembrane transport
SynNOUM97013_RS06925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynNOUM97013_RS06960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SynNOUM97013_RS06960	COG1793	dna ligase
SynNOUM97013_RS06970	COG1793	dna ligase
SynNOUM97013_RS06985	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynNOUM97013_RS07005	COG1201	RNA secondary structure unwinding
SynNOUM97013_RS07125	COG0494	nUDIX hydrolase
SynNOUM97013_RS07135	COG1119	ATPase activity
SynNOUM97013_RS07150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynNOUM97013_RS07160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynNOUM97013_RS07185	COG1376	ErfK ybiS ycfS ynhG family protein
SynNOUM97013_RS07195	COG0516	GMP reductase activity
SynNOUM97013_RS07195	COG0517	IMP dehydrogenase activity
SynNOUM97013_RS07210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynNOUM97013_RS07220	COG2197	response regulator
SynNOUM97013_RS07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynNOUM97013_RS07240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynNOUM97013_RS07255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynNOUM97013_RS07260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynNOUM97013_RS07265	COG0473	3-isopropylmalate dehydrogenase activity
SynNOUM97013_RS07270	COG3954	Phosphoribulokinase
SynNOUM97013_RS07280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynNOUM97013_RS07285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynNOUM97013_RS07295	COG0673	inositol 2-dehydrogenase activity
SynNOUM97013_RS07300	COG0191	fructose-bisphosphate aldolase activity
SynNOUM97013_RS07310	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynNOUM97013_RS07315	COG0047	phosphoribosylformylglycinamidine synthase activity
SynNOUM97013_RS07320	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynNOUM97013_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
SynNOUM97013_RS07360	COG1357	PFAM Pentapeptide repeats (8 copies)
SynNOUM97013_RS07365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynNOUM97013_RS07375	COG0129	dihydroxy-acid dehydratase activity
SynNOUM97013_RS07395	COG0363	glucosamine-6-phosphate deaminase activity
SynNOUM97013_RS07400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynNOUM97013_RS07405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynNOUM97013_RS07410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynNOUM97013_RS07415	COG1494	fructose-1,6-bisphosphatase
SynNOUM97013_RS07420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynNOUM97013_RS07450	COG2205	protein histidine kinase activity
SynNOUM97013_RS07490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynNOUM97013_RS07505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynNOUM97013_RS07515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynNOUM97013_RS07520	COG1429	ligase activity, forming nitrogen-metal bonds
SynNOUM97013_RS07530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynNOUM97013_RS07535	COG0149	triose-phosphate isomerase activity
SynNOUM97013_RS07545	COG1132	(ABC) transporter
SynNOUM97013_RS07555	COG1115	amino acid carrier protein
SynNOUM97013_RS07565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynNOUM97013_RS07575	COG0799	negative regulation of ribosome biogenesis
SynNOUM97013_RS07615	COG0659	secondary active sulfate transmembrane transporter activity
SynNOUM97013_RS07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynNOUM97013_RS07630	COG4597	amino acid ABC transporter
SynNOUM97013_RS07640	COG0765	amino acid transport
SynNOUM97013_RS07645	COG1126	abc transporter atp-binding protein
SynNOUM97013_RS07695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynNOUM97013_RS07700	COG0668	transmembrane transport
SynNOUM97013_RS07705	COG0640	Transcriptional regulator
SynNOUM97013_RS07735	COG3639	organic phosphonate transmembrane transporter activity
SynNOUM97013_RS07740	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynNOUM97013_RS07740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynNOUM97013_RS07745	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynNOUM97013_RS07750	COG0436	Aminotransferase
SynNOUM97013_RS07760	COG1573	uracil-dna glycosylase
SynNOUM97013_RS07765	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynNOUM97013_RS07770	COG0793	Belongs to the peptidase S41A family
SynNOUM97013_RS07800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynNOUM97013_RS07815	COG2124	cytochrome p450
SynNOUM97013_RS07840	COG0625	glutathione transferase activity
SynNOUM97013_RS07850	COG2197	response regulator
SynNOUM97013_RS07915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SynNOUM97013_RS07930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SynNOUM97013_RS07945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SynNOUM97013_RS08030	COG2144	transferase activity, transferring acyl groups
SynNOUM97013_RS08065	COG0515	serine threonine protein kinase
SynNOUM97013_RS08085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynNOUM97013_RS08140	COG0237	dephospho-CoA kinase activity
SynNOUM97013_RS08195	COG0484	heat shock protein binding
SynNOUM97013_RS08210	COG2274	protein secretion by the type I secretion system
SynNOUM97013_RS08215	COG1132	(ABC) transporter
SynNOUM97013_RS08250	COG0590	tRNA wobble adenosine to inosine editing
SynNOUM97013_RS08370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynNOUM97013_RS08470	COG3781	membrane
SynNOUM97013_RS08485	COG0702	epimerase
SynNOUM97013_RS08540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynNOUM97013_RS08545	COG0351	phosphomethylpyrimidine kinase
SynNOUM97013_RS08575	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynNOUM97013_RS08585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynNOUM97013_RS08605	COG0180	Tryptophanyl-tRNA synthetase
SynNOUM97013_RS08625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynNOUM97013_RS08635	COG0837	glucose binding
SynNOUM97013_RS08640	COG0083	homoserine kinase activity
SynNOUM97013_RS08645	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS08650	COG0339	signal peptide processing
SynNOUM97013_RS08680	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynNOUM97013_RS08685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynNOUM97013_RS08725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynNOUM97013_RS08730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynNOUM97013_RS08740	COG3794	PFAM blue (type 1) copper domain protein
SynNOUM97013_RS08830	COG0542	response to heat
SynNOUM97013_RS08840	COG0140	phosphoribosyl-ATP diphosphatase activity
SynNOUM97013_RS08840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynNOUM97013_RS08855	COG1376	ErfK ybiS ycfS ynhG family protein
SynNOUM97013_RS08875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS08880	COG3339	Conserved Protein
SynNOUM97013_RS08905	COG2010	Cytochrome c
SynNOUM97013_RS08920	COG0159	tryptophan synthase activity
SynNOUM97013_RS08945	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynNOUM97013_RS08945	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynNOUM97013_RS08975	COG0251	oxidation-reduction process
SynNOUM97013_RS08990	COG0418	dihydroorotase activity
SynNOUM97013_RS08995	COG0659	secondary active sulfate transmembrane transporter activity
SynNOUM97013_RS09005	COG0659	secondary active sulfate transmembrane transporter activity
SynNOUM97013_RS09010	COG0530	calcium, potassium:sodium antiporter activity
SynNOUM97013_RS09030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynNOUM97013_RS09035	COG1845	cytochrome c oxidase, subunit III
SynNOUM97013_RS09045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynNOUM97013_RS09060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynNOUM97013_RS09065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynNOUM97013_RS09080	COG0456	acetyltransferase
SynNOUM97013_RS09085	COG0596	Alpha beta hydrolase
SynNOUM97013_RS09090	COG1132	(ABC) transporter
SynNOUM97013_RS09095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynNOUM97013_RS09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynNOUM97013_RS09105	COG3842	ATPase activity
SynNOUM97013_RS09110	COG0251	oxidation-reduction process
SynNOUM97013_RS09135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS09140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynNOUM97013_RS09145	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynNOUM97013_RS09170	COG4451	ribulose bisphosphate carboxylase, small
SynNOUM97013_RS09175	COG1850	ribulose-bisphosphate carboxylase activity
SynNOUM97013_RS09180	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynNOUM97013_RS09185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynNOUM97013_RS09190	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynNOUM97013_RS09200	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynNOUM97013_RS09205	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynNOUM97013_RS09210	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynNOUM97013_RS09255	COG0730	response to heat
SynNOUM97013_RS09260	COG0095	Lipoate-protein ligase
SynNOUM97013_RS09265	COG1994	Peptidase M50
SynNOUM97013_RS09265	COG0517	IMP dehydrogenase activity
SynNOUM97013_RS09270	COG0135	phosphoribosylanthranilate isomerase activity
SynNOUM97013_RS09275	COG0302	gtp cyclohydrolase
SynNOUM97013_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
SynNOUM97013_RS09285	COG0825	malonyl-CoA metabolic process
SynNOUM97013_RS09290	COG5322	oxidoreductase activity
SynNOUM97013_RS09295	COG3396	Phenylacetate-CoA oxygenase
SynNOUM97013_RS09305	COG0539	negative regulation of cytoplasmic translation
SynNOUM97013_RS09315	COG1496	oxidoreductase activity
SynNOUM97013_RS09320	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynNOUM97013_RS09340	COG0028	Belongs to the TPP enzyme family
SynNOUM97013_RS09345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynNOUM97013_RS09355	COG2226	methyltransferase
SynNOUM97013_RS09370	COG0528	UMP kinase activity
SynNOUM97013_RS09375	COG0233	cytoplasmic translational termination
SynNOUM97013_RS09385	COG0415	Belongs to the DNA photolyase family
SynNOUM97013_RS09395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynNOUM97013_RS09400	COG0768	penicillin binding
SynNOUM97013_RS09420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynNOUM97013_RS09425	COG0681	Belongs to the peptidase S26 family
SynNOUM97013_RS09445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynNOUM97013_RS09455	COG0442	prolyl-tRNA aminoacylation
SynNOUM97013_RS09465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynNOUM97013_RS09470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynNOUM97013_RS09485	COG0629	single-stranded DNA binding
SynNOUM97013_RS09500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynNOUM97013_RS09510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynNOUM97013_RS09515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS09585	COG0181	hydroxymethylbilane synthase activity
SynNOUM97013_RS09590	COG2095	MarC family integral membrane protein
SynNOUM97013_RS09605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynNOUM97013_RS09610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynNOUM97013_RS09620	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynNOUM97013_RS09625	COG0523	cobalamin synthesis protein
SynNOUM97013_RS09645	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynNOUM97013_RS09675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynNOUM97013_RS09685	COG3239	Fatty acid desaturase
SynNOUM97013_RS09690	COG1666	GTP binding
SynNOUM97013_RS09700	COG0330	HflC and HflK could
SynNOUM97013_RS09715	COG0857	belongs to the CobB CobQ family
SynNOUM97013_RS09725	COG3000	fatty acid hydroxylase
SynNOUM97013_RS09725	COG0300	oxidoreductase activity
SynNOUM97013_RS09730	COG0024	Methionine aminopeptidase
SynNOUM97013_RS09740	COG0335	large ribosomal subunit rRNA binding
SynNOUM97013_RS09765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynNOUM97013_RS09770	COG3263	regulation of cellular component size
SynNOUM97013_RS09785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynNOUM97013_RS09795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynNOUM97013_RS09800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynNOUM97013_RS09815	COG0194	GDP metabolic process
SynNOUM97013_RS09825	COG0805	protein transport
SynNOUM97013_RS09835	COG0723	plastoquinol--plastocyanin reductase activity
SynNOUM97013_RS09840	COG3258	Cytochrome c
SynNOUM97013_RS09870	COG0248	Ppx GppA phosphatase
SynNOUM97013_RS09875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynNOUM97013_RS09880	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynNOUM97013_RS09885	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynNOUM97013_RS09895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynNOUM97013_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
SynNOUM97013_RS09910	COG0459	protein refolding
SynNOUM97013_RS09920	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynNOUM97013_RS09940	COG0109	protoheme IX farnesyltransferase activity
SynNOUM97013_RS09945	COG1612	heme a metabolic process
SynNOUM97013_RS09955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynNOUM97013_RS09960	COG1845	cytochrome c oxidase, subunit III
SynNOUM97013_RS09985	COG0656	L-ascorbic acid biosynthetic process
SynNOUM97013_RS09995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynNOUM97013_RS10010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynNOUM97013_RS10015	COG1007	ATP synthesis coupled electron transport
SynNOUM97013_RS10020	COG0577	efflux transmembrane transporter activity
SynNOUM97013_RS10020	COG1136	(ABC) transporter
SynNOUM97013_RS10025	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS10030	COG0739	heme binding
SynNOUM97013_RS10035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynNOUM97013_RS10035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynNOUM97013_RS10040	COG0436	Aminotransferase
SynNOUM97013_RS10045	COG3118	belongs to the thioredoxin family
SynNOUM97013_RS10050	COG1842	Phage shock protein A
SynNOUM97013_RS10060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynNOUM97013_RS10070	COG0697	spore germination
SynNOUM97013_RS10075	COG0616	signal peptide processing
SynNOUM97013_RS10090	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynNOUM97013_RS10095	COG0594	ribonuclease P activity
SynNOUM97013_RS10105	COG0706	membrane insertase activity
SynNOUM97013_RS10115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynNOUM97013_RS10125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynNOUM97013_RS10130	COG0750	zinc metalloprotease
SynNOUM97013_RS10135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynNOUM97013_RS10140	COG1185	polyribonucleotide nucleotidyltransferase activity
SynNOUM97013_RS10150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynNOUM97013_RS10240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynNOUM97013_RS10285	COG0776	regulation of translation
SynNOUM97013_RS10305	COG2211	Major facilitator Superfamily
SynNOUM97013_RS10310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynNOUM97013_RS10325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynNOUM97013_RS10355	COG0284	orotidine-5'-phosphate decarboxylase activity
SynNOUM97013_RS10370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynNOUM97013_RS10395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynNOUM97013_RS10410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynNOUM97013_RS10420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynNOUM97013_RS10425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynNOUM97013_RS10430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynNOUM97013_RS10440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynNOUM97013_RS10450	COG0151	Belongs to the GarS family
SynNOUM97013_RS10455	COG5002	protein histidine kinase activity
SynNOUM97013_RS10460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynNOUM97013_RS10465	COG4251	negative regulation of phosphorylation
SynNOUM97013_RS10475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynNOUM97013_RS10480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynNOUM97013_RS10490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynNOUM97013_RS10495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynNOUM97013_RS10500	COG0217	transcriptional regulatory protein
SynNOUM97013_RS10530	COG0363	glucosamine-6-phosphate deaminase activity
SynNOUM97013_RS10535	COG2385	sporulation resulting in formation of a cellular spore
SynNOUM97013_RS10535	COG2247	cell wall binding repeat
SynNOUM97013_RS10540	COG1234	tRNA 3'-trailer cleavage
SynNOUM97013_RS10545	COG2010	Cytochrome c
SynNOUM97013_RS10560	COG2264	protein methyltransferase activity
SynNOUM97013_RS10565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynNOUM97013_RS10585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynNOUM97013_RS10620	COG0443	Heat shock 70 kDa protein
SynNOUM97013_RS10635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynNOUM97013_RS10655	COG0459	protein refolding
SynNOUM97013_RS10660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynNOUM97013_RS10665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynNOUM97013_RS10670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynNOUM97013_RS10690	COG0006	proline dipeptidase activity
SynNOUM97013_RS10695	COG1253	flavin adenine dinucleotide binding
SynNOUM97013_RS10700	COG1160	GTP binding
SynNOUM97013_RS10705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynNOUM97013_RS10710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynNOUM97013_RS10710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynNOUM97013_RS10715	COG0686	Belongs to the AlaDH PNT family
SynNOUM97013_RS10720	COG3012	SEC-C Motif Domain Protein
SynNOUM97013_RS10725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynNOUM97013_RS10735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynNOUM97013_RS10745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynNOUM97013_RS10750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynNOUM97013_RS10755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynNOUM97013_RS10760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynNOUM97013_RS10765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynNOUM97013_RS10770	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynNOUM97013_RS10775	COG0356	it plays a direct role in the translocation of protons across the membrane
SynNOUM97013_RS10785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynNOUM97013_RS10790	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynNOUM97013_RS10810	COG0772	Belongs to the SEDS family
SynNOUM97013_RS10815	COG4232	protein-disulfide reductase activity
SynNOUM97013_RS10820	COG1333	cytochrome c biogenesis protein
SynNOUM97013_RS10825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynNOUM97013_RS10840	COG0347	Belongs to the P(II) protein family
SynNOUM97013_RS10855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynNOUM97013_RS10865	COG0114	fumarate hydratase activity
SynNOUM97013_RS10870	COG4581	dead DEAH box helicase
SynNOUM97013_RS10875	COG0385	Bile acid
SynNOUM97013_RS10880	COG0156	8-amino-7-oxononanoate synthase activity
SynNOUM97013_RS10895	COG4106	trans-aconitate 2-methyltransferase activity
SynNOUM97013_RS10895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynNOUM97013_RS10910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynNOUM97013_RS10925	COG0357	Ribosomal RNA small subunit methyltransferase G
SynNOUM97013_RS10960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynNOUM97013_RS10965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynNOUM97013_RS10970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynNOUM97013_RS10975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynNOUM97013_RS10980	COG0085	RNA polymerase activity
SynNOUM97013_RS10985	COG0084	hydrolase, TatD family'
SynNOUM97013_RS10990	COG0268	Binds directly to 16S ribosomal RNA
SynNOUM97013_RS10995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynNOUM97013_RS11000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynNOUM97013_RS11005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynNOUM97013_RS11025	COG0641	radical SAM
SynNOUM97013_RS11030	COG0779	Required for maturation of 30S ribosomal subunits
SynNOUM97013_RS11035	COG0195	Participates in both transcription termination and antitermination
SynNOUM97013_RS11045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynNOUM97013_RS11095	COG2988	succinylglutamate desuccinylase activity
SynNOUM97013_RS11100	COG0435	Glutathione S-transferase
SynNOUM97013_RS11110	COG0488	(ABC) transporter
SynNOUM97013_RS11130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynNOUM97013_RS11140	COG1193	negative regulation of DNA recombination
SynNOUM97013_RS11150	COG0113	porphobilinogen synthase activity
SynNOUM97013_RS11155	COG0484	heat shock protein binding
SynNOUM97013_RS11165	COG0659	secondary active sulfate transmembrane transporter activity
SynNOUM97013_RS11210	COG3659	wide pore channel activity
SynNOUM97013_RS11235	COG0116	Belongs to the methyltransferase superfamily
SynNOUM97013_RS11255	COG1196	nuclear chromosome segregation
SynNOUM97013_RS11265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynNOUM97013_RS11280	COG0439	Biotin carboxylase
SynNOUM97013_RS11295	COG0515	serine threonine protein kinase
SynNOUM97013_RS11315	COG4178	(ABC) transporter
SynNOUM97013_RS11320	COG0537	adenosine 5'-monophosphoramidase activity
SynNOUM97013_RS11335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynNOUM97013_RS11350	COG0242	peptide deformylase activity
SynNOUM97013_RS11360	COG0235	Class ii aldolase
SynNOUM97013_RS11365	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynNOUM97013_RS11375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynNOUM97013_RS11380	COG0719	Fe-S assembly protein
SynNOUM97013_RS11385	COG0396	ATPase activity
SynNOUM97013_RS11390	COG0719	Fe-S assembly protein
SynNOUM97013_RS11395	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynNOUM97013_RS11415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynNOUM97013_RS11430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SynNOUM97013_RS11435	COG0457	Tetratricopeptide repeat
SynNOUM97013_RS11465	COG0033	Phosphoglucomutase
SynNOUM97013_RS11475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynNOUM97013_RS11505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynNOUM97013_RS11510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynNOUM97013_RS11515	COG0175	sulfate reduction
SynNOUM97013_RS11520	COG1252	NADH dehydrogenase
SynNOUM97013_RS11525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynNOUM97013_RS11530	COG3273	potassium ion transport
SynNOUM97013_RS11530	COG0471	metal ion transport
SynNOUM97013_RS11535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynNOUM97013_RS11540	COG0569	domain protein
SynNOUM97013_RS11545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynNOUM97013_RS11565	COG0488	(ABC) transporter
SynNOUM97013_RS11575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynNOUM97013_RS11590	COG1643	Atp-dependent helicase
SynNOUM97013_RS11595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynNOUM97013_RS11605	COG1570	exodeoxyribonuclease VII activity
SynNOUM97013_RS11655	COG0483	inositol monophosphate 1-phosphatase activity
SynNOUM97013_RS11670	COG1968	undecaprenyl-diphosphatase activity
SynNOUM97013_RS11680	COG1555	photosystem II stabilization
SynNOUM97013_RS11685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynNOUM97013_RS11695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynNOUM97013_RS11710	COG1032	radical SAM domain protein
SynNOUM97013_RS11740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynNOUM97013_RS11765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynNOUM97013_RS11775	COG0463	Glycosyl transferase, family 2
SynNOUM97013_RS11775	COG0457	Tetratricopeptide repeat
SynNOUM97013_RS11780	COG1587	Uroporphyrinogen-III synthase
SynNOUM97013_RS11795	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynNOUM97013_RS11800	COG0316	Belongs to the HesB IscA family
SynNOUM97013_RS11820	COG1090	epimerase
SynNOUM97013_RS11825	COG3263	regulation of cellular component size
SynNOUM97013_RS11840	COG0484	heat shock protein binding
SynNOUM97013_RS11845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynNOUM97013_RS11850	COG3659	wide pore channel activity
SynNOUM97013_RS11890	COG1122	ATPase activity
SynNOUM97013_RS11900	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS11910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynNOUM97013_RS11915	COG2217	Heavy metal translocating P-type atpase
SynNOUM97013_RS11920	COG3063	Type IV pilus biogenesis stability protein PilW
SynNOUM97013_RS11925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynNOUM97013_RS11935	COG0416	fatty acid biosynthetic process
SynNOUM97013_RS11940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynNOUM97013_RS11945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynNOUM97013_RS11950	COG0318	PFAM AMP-dependent synthetase and ligase
SynNOUM97013_RS11950	COG0204	Acyl-transferase
SynNOUM97013_RS11960	COG1214	PFAM Peptidase M22, glycoprotease
SynNOUM97013_RS11970	COG0617	tRNA 3'-terminal CCA addition
SynNOUM97013_RS12030	COG2894	cell division
SynNOUM97013_RS12040	COG1562	ergosterol biosynthetic process
SynNOUM97013_RS12045	COG2205	protein histidine kinase activity
SynNOUM97013_RS12045	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS12045	COG3292	Two component regulator propeller
SynNOUM97013_RS12055	COG2205	protein histidine kinase activity
SynNOUM97013_RS12055	COG0784	Response regulator, receiver
SynNOUM97013_RS12055	COG2198	Histidine kinase
SynNOUM97013_RS12060	COG0493	'glutamate synthase
SynNOUM97013_RS12060	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynNOUM97013_RS12075	COG0583	DNA-binding transcription factor activity
SynNOUM97013_RS12085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynNOUM97013_RS12090	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS12105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynNOUM97013_RS12115	COG2197	response regulator
SynNOUM97013_RS12125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynNOUM97013_RS12130	COG0713	ATP synthesis coupled electron transport
SynNOUM97013_RS12135	COG0839	Belongs to the complex I subunit 6 family
SynNOUM97013_RS12140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynNOUM97013_RS12145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynNOUM97013_RS12150	COG0372	Belongs to the citrate synthase family
SynNOUM97013_RS12170	COG1420	regulation of RNA biosynthetic process
SynNOUM97013_RS12175	COG0133	tryptophan synthase activity
SynNOUM97013_RS12185	COG0023	Translation Initiation Factor
SynNOUM97013_RS12190	COG0529	Catalyzes the synthesis of activated sulfate
SynNOUM97013_RS12195	COG0628	permease
SynNOUM97013_RS12205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynNOUM97013_RS12215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynNOUM97013_RS12220	COG0564	pseudouridine synthase activity
SynNOUM97013_RS12225	COG0745	RESPONSE REGULATOR receiver
SynNOUM97013_RS12245	COG0275	rRNA processing
SynNOUM97013_RS12250	COG0649	NAD binding
SynNOUM97013_RS12265	COG0824	Thioesterase
SynNOUM97013_RS12290	COG1575	Belongs to the MenA family. Type 1 subfamily
SynNOUM97013_RS12305	COG0189	ligase activity
SynNOUM97013_RS12310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynNOUM97013_RS12315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynNOUM97013_RS12330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynNOUM97013_RS12335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynNOUM97013_RS12340	COG0512	Glutamine amidotransferase of anthranilate synthase
SynNOUM97013_RS12360	COG0252	asparaginase activity
SynNOUM97013_RS12365	COG0018	arginyl-trna synthetase
SynNOUM97013_RS12370	COG0157	Belongs to the NadC ModD family
SynNOUM97013_RS12380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynNOUM97013_RS12390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynNOUM97013_RS12395	COG4172	Belongs to the ABC transporter superfamily
SynNOUM97013_RS12405	COG0564	pseudouridine synthase activity
SynNOUM97013_RS12415	COG0589	response to stress
SynNOUM97013_RS12420	COG0126	phosphoglycerate kinase activity
SynNOUM97013_RS12465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynNOUM97013_RS12470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynNOUM97013_RS12500	COG0167	dihydroorotate dehydrogenase activity
SynNOUM97013_RS12505	COG0328	RNA-DNA hybrid ribonuclease activity
SynNOUM97013_RS12515	COG0222	ribosome binding
SynNOUM97013_RS12520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynNOUM97013_RS12525	COG0081	regulation of translation
SynNOUM97013_RS12530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynNOUM97013_RS12535	COG0250	Participates in transcription elongation, termination and antitermination
SynNOUM97013_RS12540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynNOUM97013_RS12545	COG0542	response to heat
SynNOUM97013_RS12550	COG0346	lactoylglutathione lyase activity
SynNOUM97013_RS12555	COG0148	phosphopyruvate hydratase activity
SynNOUM97013_RS12560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynNOUM97013_RS12590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynNOUM97013_RS12595	COG0237	dephospho-CoA kinase activity
SynNOUM97013_RS12605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynNOUM97013_RS12615	COG2022	thiamine diphosphate biosynthetic process
SynNOUM97013_RS12615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynNOUM97013_RS12625	COG0105	UTP biosynthetic process
SynNOUM97013_RS12630	COG1166	arginine decarboxylase activity
SynNOUM97013_RS12650	COG1803	Methylglyoxal synthase
SynNOUM97013_RS12655	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SynNOUM97013_RS12690	COG0668	transmembrane transport
SynNOUM97013_RS12720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynNOUM97013_RS12730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynNOUM97013_RS12755	COG0426	domain, Protein
SynNOUM97013_RS12755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynNOUM97013_RS12760	COG0426	domain, Protein
SynNOUM97013_RS12760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynNOUM97013_RS12765	COG1773	rubredoxin
SynNOUM97013_RS12765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynNOUM97013_RS12775	COG1741	Belongs to the pirin family
SynNOUM97013_RS12795	COG0509	glycine decarboxylation via glycine cleavage system
SynNOUM97013_RS12800	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynNOUM97013_RS12820	COG0359	binds to the 23S rRNA
SynNOUM97013_RS12825	COG1372	Participates in initiation and elongation during chromosome replication
SynNOUM97013_RS12825	COG0305	Participates in initiation and elongation during chromosome replication
SynNOUM97013_RS12825	COG1372	Participates in initiation and elongation during chromosome replication
SynNOUM97013_RS12825	COG0305	Participates in initiation and elongation during chromosome replication
SynNOUM97013_RS12860	COG0445	tRNA wobble uridine modification
SynNOUM97013_RS12900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynNOUM97013_RS12915	COG0398	Pfam SNARE associated Golgi protein
SynNOUM97013_RS12925	COG0668	transmembrane transport
SynNOUM97013_RS12930	COG0668	transmembrane transport
SynNOUM97013_RS12950	COG0525	valine-tRNA ligase activity
SynNOUM97013_RS12965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynNOUM97013_RS12965	COG3264	Mechanosensitive ion channel
SynNOUM97013_RS12985	COG4221	oxidoreductase activity
SynNOUM97013_RS13020	COG3956	TIGRFAM MazG family protein
SynNOUM97013_RS13030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynNOUM97013_RS13045	COG0010	Belongs to the arginase family
SynNOUM97013_RS13060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynNOUM97013_RS13065	COG2208	phosphoserine phosphatase activity
SynNOUM97013_RS13065	COG2770	Histidine kinase
SynNOUM97013_RS13105	COG2208	phosphoserine phosphatase activity
SynNOUM97013_RS13105	COG2770	Histidine kinase
SynNOUM97013_RS13115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynNOUM97013_RS13120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS13125	COG0783	Belongs to the Dps family
SynNOUM97013_RS13130	COG0504	CTP synthase activity
SynNOUM97013_RS13135	COG0602	queuosine metabolic process
SynNOUM97013_RS13140	COG4942	peptidase
SynNOUM97013_RS13145	COG4574	serine-type endopeptidase inhibitor activity
SynNOUM97013_RS13150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynNOUM97013_RS13175	COG3769	mannosylglycerate metabolic process
SynNOUM97013_RS13180	COG0366	Alpha amylase catalytic
SynNOUM97013_RS13220	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynNOUM97013_RS13225	COG0830	nickel cation binding
SynNOUM97013_RS13230	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynNOUM97013_RS13235	COG0829	nickel cation binding
SynNOUM97013_RS13240	COG0831	urea catabolic process
SynNOUM97013_RS13245	COG0832	Belongs to the urease beta subunit family
SynNOUM97013_RS13250	COG0804	urea catabolic process
SynNOUM97013_RS13255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynNOUM97013_RS13275	COG0367	asparagine synthase
SynNOUM97013_RS13280	COG0540	Belongs to the ATCase OTCase family
SynNOUM97013_RS13295	COG2308	Evidence 4 Homologs of previously reported genes of
SynNOUM97013_RS13315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynNOUM97013_RS13325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynNOUM97013_RS13335	COG2223	nitrite transmembrane transporter activity
SynNOUM97013_RS13340	COG0243	molybdopterin cofactor binding
SynNOUM97013_RS13355	COG0315	cyclic pyranopterin monophosphate synthase activity
SynNOUM97013_RS13360	COG0303	'Molybdopterin
SynNOUM97013_RS13370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynNOUM97013_RS13375	COG0314	molybdopterin synthase activity
SynNOUM97013_RS13385	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynNOUM97013_RS13390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynNOUM97013_RS13405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynNOUM97013_RS13410	COG2116	formate transmembrane transporter activity
SynNOUM97013_RS13420	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynNOUM97013_RS13430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynNOUM97013_RS13445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynNOUM97013_RS13450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynNOUM97013_RS13455	COG0170	dolichyl monophosphate biosynthetic process
SynNOUM97013_RS13465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynNOUM97013_RS13470	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynNOUM97013_RS13490	COG0788	formyltetrahydrofolate deformylase activity
SynNOUM97013_RS13510	COG0443	Heat shock 70 kDa protein
SynNOUM97013_RS13515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynNOUM97013_RS13525	COG0360	Binds together with S18 to 16S ribosomal RNA
SynNOUM97013_RS13535	COG0137	argininosuccinate synthase activity
SynNOUM97013_RS13550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynNOUM97013_RS13570	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynNOUM97013_RS13575	COG0438	transferase activity, transferring glycosyl groups
SynNOUM97013_RS13585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynNOUM97013_RS13590	COG0497	DNA recombination
SynNOUM97013_RS13595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynNOUM97013_RS13605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine