locus-tag	class	description
AWQ21_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ21_RS00010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWQ21_RS00035	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AWQ21_RS00040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWQ21_RS00045	COG0662	Cupin 2, conserved barrel domain protein
AWQ21_RS00045	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AWQ21_RS00050	COG1393	Belongs to the ArsC family
AWQ21_RS00055	COG4636	protein conserved in cyanobacteria
AWQ21_RS00095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS00100	COG0742	ribosomal rna small subunit methyltransferase
AWQ21_RS00120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AWQ21_RS00125	COG0351	phosphomethylpyrimidine kinase
AWQ21_RS00130	COG1160	GTP binding
AWQ21_RS00140	COG0572	uridine kinase
AWQ21_RS00150	COG0783	Belongs to the Dps family
AWQ21_RS00165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWQ21_RS00175	COG0180	Tryptophanyl-tRNA synthetase
AWQ21_RS00185	COG0384	phenazine biosynthesis protein PhzF
AWQ21_RS00190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS00215	COG0784	Response regulator, receiver
AWQ21_RS00230	COG0840	transmembrane signaling receptor activity
AWQ21_RS00230	COG2203	Gaf domain
AWQ21_RS00235	COG2198	Histidine kinase
AWQ21_RS00235	COG0784	Response regulator, receiver
AWQ21_RS00235	COG0643	Histidine kinase
AWQ21_RS00250	COG0511	ligase activity, forming carbon-carbon bonds
AWQ21_RS00255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AWQ21_RS00265	COG1487	ribonuclease activity
AWQ21_RS00285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AWQ21_RS00295	COG0494	nUDIX hydrolase
AWQ21_RS00300	COG0571	ribonuclease III activity
AWQ21_RS00310	COG1615	UPF0182 protein
AWQ21_RS00315	COG0737	Belongs to the 5'-nucleotidase family
AWQ21_RS00325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AWQ21_RS00330	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ21_RS00335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWQ21_RS00340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWQ21_RS00345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AWQ21_RS00355	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AWQ21_RS00360	COG0148	phosphopyruvate hydratase activity
AWQ21_RS00365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AWQ21_RS00370	COG1472	Belongs to the glycosyl hydrolase 3 family
AWQ21_RS00385	COG3937	granule-associated protein
AWQ21_RS00395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ21_RS00415	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWQ21_RS00415	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWQ21_RS00450	COG0083	homoserine kinase activity
AWQ21_RS00465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AWQ21_RS00470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ21_RS00475	COG0456	acetyltransferase
AWQ21_RS00485	COG0019	diaminopimelate decarboxylase activity
AWQ21_RS00490	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWQ21_RS00495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWQ21_RS00520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AWQ21_RS00525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AWQ21_RS00530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AWQ21_RS00535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWQ21_RS00545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWQ21_RS00550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AWQ21_RS00555	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ21_RS00560	COG2010	Cytochrome c
AWQ21_RS00580	COG0656	L-ascorbic acid biosynthetic process
AWQ21_RS00585	COG0386	Belongs to the glutathione peroxidase family
AWQ21_RS00595	COG0629	single-stranded DNA binding
AWQ21_RS00600	COG4172	Belongs to the ABC transporter superfamily
AWQ21_RS00605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWQ21_RS00610	COG0494	nUDIX hydrolase
AWQ21_RS00615	COG1160	GTP binding
AWQ21_RS00620	COG3268	Saccharopine dehydrogenase
AWQ21_RS00625	COG2116	formate transmembrane transporter activity
AWQ21_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ21_RS00640	COG1959	2 iron, 2 sulfur cluster binding
AWQ21_RS00655	COG0789	Transcriptional regulator
AWQ21_RS00665	COG1175	transmembrane transport
AWQ21_RS00670	COG0728	peptidoglycan biosynthetic process
AWQ21_RS00680	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWQ21_RS00690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AWQ21_RS00705	COG0542	response to heat
AWQ21_RS00720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ21_RS00730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AWQ21_RS00735	COG0459	protein refolding
AWQ21_RS00755	COG0737	Belongs to the 5'-nucleotidase family
AWQ21_RS00760	COG0668	transmembrane transport
AWQ21_RS00780	COG0756	dUTP diphosphatase activity
AWQ21_RS00800	COG3239	Fatty acid desaturase
AWQ21_RS00820	COG0205	6-phosphofructokinase activity
AWQ21_RS00840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ21_RS00845	COG1131	(ABC) transporter
AWQ21_RS00850	COG2010	Cytochrome c
AWQ21_RS00860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWQ21_RS00865	COG2124	cytochrome p450
AWQ21_RS00870	COG0583	DNA-binding transcription factor activity
AWQ21_RS00875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ21_RS00880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS00890	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ21_RS00895	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AWQ21_RS00895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AWQ21_RS00900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWQ21_RS00905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWQ21_RS00935	COG0463	Glycosyl transferase, family 2
AWQ21_RS00935	COG0457	Tetratricopeptide repeat
AWQ21_RS00950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ21_RS00960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AWQ21_RS00975	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AWQ21_RS00980	COG4636	protein conserved in cyanobacteria
AWQ21_RS00985	COG0804	urea catabolic process
AWQ21_RS01010	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AWQ21_RS01020	COG3259	Nickel-dependent hydrogenase
AWQ21_RS01035	COG0375	protein maturation
AWQ21_RS01040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ21_RS01045	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AWQ21_RS01055	COG0298	carbon dioxide binding
AWQ21_RS01075	COG1490	D-aminoacyl-tRNA deacylase activity
AWQ21_RS01095	COG0793	Belongs to the peptidase S41A family
AWQ21_RS01105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ21_RS01110	COG0702	epimerase
AWQ21_RS01115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ21_RS01120	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS01130	COG2003	Belongs to the UPF0758 family
AWQ21_RS01135	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWQ21_RS01140	COG0312	modulator of DNA gyrase
AWQ21_RS01155	COG0316	Belongs to the HesB IscA family
AWQ21_RS01165	COG1773	rubredoxin
AWQ21_RS01170	COG4447	cellulose binding
AWQ21_RS01185	COG3977	Valine--pyruvate aminotransferase
AWQ21_RS01195	COG0322	excinuclease ABC activity
AWQ21_RS01210	COG1131	(ABC) transporter
AWQ21_RS01220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AWQ21_RS01235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ21_RS01245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AWQ21_RS01255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AWQ21_RS01255	COG0574	Belongs to the PEP-utilizing enzyme family
AWQ21_RS01285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AWQ21_RS01305	COG1968	undecaprenyl-diphosphatase activity
AWQ21_RS01315	COG0321	lipoyl(octanoyl) transferase activity
AWQ21_RS01320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AWQ21_RS01330	COG0516	GMP reductase activity
AWQ21_RS01350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ21_RS01360	COG1834	amidinotransferase
AWQ21_RS01365	COG0724	RNA recognition motif
AWQ21_RS01370	COG2239	Acts as a magnesium transporter
AWQ21_RS01400	COG0352	thiamine-phosphate diphosphorylase activity
AWQ21_RS01405	COG0602	queuosine metabolic process
AWQ21_RS01410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AWQ21_RS01415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ21_RS01420	COG0475	glutathione-regulated potassium exporter activity
AWQ21_RS01420	COG0589	response to stress
AWQ21_RS01430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AWQ21_RS01435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWQ21_RS01445	COG0113	porphobilinogen synthase activity
AWQ21_RS01450	COG0302	gtp cyclohydrolase
AWQ21_RS01460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWQ21_RS01475	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AWQ21_RS01480	COG4251	negative regulation of phosphorylation
AWQ21_RS01490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ21_RS01500	COG0436	Aminotransferase
AWQ21_RS01505	COG3118	belongs to the thioredoxin family
AWQ21_RS01510	COG1842	Phage shock protein A
AWQ21_RS01515	COG4251	negative regulation of phosphorylation
AWQ21_RS01520	COG0133	tryptophan synthase activity
AWQ21_RS01545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AWQ21_RS01550	COG0783	Belongs to the Dps family
AWQ21_RS01555	COG4572	Cation transport regulator
AWQ21_RS01575	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AWQ21_RS01585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWQ21_RS01595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AWQ21_RS01610	COG0673	inositol 2-dehydrogenase activity
AWQ21_RS01620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AWQ21_RS01625	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWQ21_RS01630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AWQ21_RS01635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AWQ21_RS01640	COG0450	alkyl hydroperoxide reductase
AWQ21_RS01645	COG1555	photosystem II stabilization
AWQ21_RS01655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWQ21_RS01670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWQ21_RS01675	COG1032	radical SAM domain protein
AWQ21_RS01685	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AWQ21_RS01690	COG1640	4-alpha-glucanotransferase
AWQ21_RS01700	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AWQ21_RS01725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AWQ21_RS01730	COG0346	lactoylglutathione lyase activity
AWQ21_RS01735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ21_RS01745	COG4953	penicillin-binding protein 1C
AWQ21_RS01755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ21_RS01765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AWQ21_RS01765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWQ21_RS01770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ21_RS01775	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWQ21_RS01785	COG0517	IMP dehydrogenase activity
AWQ21_RS01785	COG0516	GMP reductase activity
AWQ21_RS01805	COG3237	CsbD-like
AWQ21_RS01810	COG3237	CsbD-like
AWQ21_RS01825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS01835	COG0509	glycine decarboxylation via glycine cleavage system
AWQ21_RS01840	COG0006	proline dipeptidase activity
AWQ21_RS01845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWQ21_RS01850	COG0484	heat shock protein binding
AWQ21_RS01860	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AWQ21_RS01895	COG0606	chelatase, subunit chli
AWQ21_RS01905	COG1316	TRANSCRIPTIONal
AWQ21_RS01915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ21_RS01920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWQ21_RS01925	COG0157	Belongs to the NadC ModD family
AWQ21_RS01935	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWQ21_RS01950	COG2208	phosphoserine phosphatase activity
AWQ21_RS01955	COG0463	Glycosyl transferase, family 2
AWQ21_RS01955	COG1216	Glycosyl transferase, family 2
AWQ21_RS01960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWQ21_RS01970	COG2010	Cytochrome c
AWQ21_RS02005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ21_RS02015	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWQ21_RS02020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ21_RS02030	COG0752	glycyl-tRNA synthetase alpha subunit
AWQ21_RS02035	COG3001	Fructosamine kinase
AWQ21_RS02045	COG1214	PFAM Peptidase M22, glycoprotease
AWQ21_RS02050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AWQ21_RS02060	COG0747	negative chemotaxis
AWQ21_RS02065	COG1606	tRNA processing
AWQ21_RS02100	COG0285	dihydrofolate synthase activity
AWQ21_RS02115	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS02120	COG1091	dTDP-4-dehydrorhamnose reductase activity
AWQ21_RS02135	COG1088	dTDP-glucose 4,6-dehydratase activity
AWQ21_RS02190	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWQ21_RS02210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AWQ21_RS02215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ21_RS02215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWQ21_RS02220	COG3850	Histidine kinase
AWQ21_RS02220	COG3437	response regulator, receiver
AWQ21_RS02220	COG2205	protein histidine kinase activity
AWQ21_RS02220	COG4999	Histidine kinase
AWQ21_RS02230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AWQ21_RS02235	COG0542	response to heat
AWQ21_RS02245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AWQ21_RS02265	COG0732	type I restriction modification DNA specificity domain
AWQ21_RS02280	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AWQ21_RS02285	COG0339	signal peptide processing
AWQ21_RS02290	COG0308	aminopeptidase N
AWQ21_RS02295	COG0673	inositol 2-dehydrogenase activity
AWQ21_RS02330	COG0360	Binds together with S18 to 16S ribosomal RNA
AWQ21_RS02340	COG0747	negative chemotaxis
AWQ21_RS02345	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ21_RS02345	COG0515	serine threonine protein kinase
AWQ21_RS02350	COG0072	phenylalanine-tRNA ligase activity
AWQ21_RS02350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ21_RS02360	COG4636	protein conserved in cyanobacteria
AWQ21_RS02365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ21_RS02370	COG0497	DNA recombination
AWQ21_RS02375	COG0784	Response regulator, receiver
AWQ21_RS02375	COG2205	protein histidine kinase activity
AWQ21_RS02375	COG5002	protein histidine kinase activity
AWQ21_RS02385	COG0631	protein serine/threonine phosphatase activity
AWQ21_RS02390	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ21_RS02395	COG3937	granule-associated protein
AWQ21_RS02400	COG0066	3-isopropylmalate dehydratase activity
AWQ21_RS02405	COG0720	synthase
AWQ21_RS02410	COG1070	Carbohydrate kinase
AWQ21_RS02415	COG0515	serine threonine protein kinase
AWQ21_RS02420	COG2211	Major facilitator Superfamily
AWQ21_RS02445	COG3781	membrane
AWQ21_RS02465	COG2308	Evidence 4 Homologs of previously reported genes of
AWQ21_RS02480	COG0347	Belongs to the P(II) protein family
AWQ21_RS02490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWQ21_RS02500	COG0612	Peptidase, M16
AWQ21_RS02520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AWQ21_RS02525	COG0613	PHP domain protein
AWQ21_RS02530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ21_RS02535	COG0284	orotidine-5'-phosphate decarboxylase activity
AWQ21_RS02540	COG0271	Belongs to the BolA IbaG family
AWQ21_RS02545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWQ21_RS02570	COG0484	heat shock protein binding
AWQ21_RS02595	COG1215	transferase activity, transferring glycosyl groups
AWQ21_RS02600	COG4636	protein conserved in cyanobacteria
AWQ21_RS02615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ21_RS02635	COG0416	fatty acid biosynthetic process
AWQ21_RS02640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AWQ21_RS02650	COG2226	methyltransferase
AWQ21_RS02655	COG1162	GTPase activity
AWQ21_RS02660	COG0612	Peptidase, M16
AWQ21_RS02665	COG0671	phosphoesterase, PA-phosphatase related
AWQ21_RS02670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AWQ21_RS02680	COG0228	four-way junction DNA binding
AWQ21_RS02690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AWQ21_RS02700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AWQ21_RS02705	COG2894	cell division
AWQ21_RS02710	COG0850	regulation of cytokinetic process
AWQ21_RS02715	COG0436	Aminotransferase
AWQ21_RS02720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWQ21_RS02740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWQ21_RS02740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ21_RS02755	COG1943	Transposase
AWQ21_RS02800	COG1126	abc transporter atp-binding protein
AWQ21_RS02805	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS02815	COG2314	TM2 domain
AWQ21_RS02820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWQ21_RS02825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ21_RS02835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AWQ21_RS02840	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWQ21_RS02845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AWQ21_RS02845	COG0140	phosphoribosyl-ATP diphosphatase activity
AWQ21_RS02855	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS02860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWQ21_RS02870	COG1994	Peptidase M50
AWQ21_RS02870	COG0517	IMP dehydrogenase activity
AWQ21_RS02880	COG0058	SHG alpha-glucan phosphorylase activity
AWQ21_RS02895	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWQ21_RS02900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWQ21_RS02905	COG0235	Class ii aldolase
AWQ21_RS02925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWQ21_RS02930	COG0450	alkyl hydroperoxide reductase
AWQ21_RS02950	COG0159	tryptophan synthase activity
AWQ21_RS02960	COG4243	Vitamin k epoxide reductase
AWQ21_RS02965	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWQ21_RS03000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AWQ21_RS03005	COG0557	exoribonuclease II activity
AWQ21_RS03020	COG0475	glutathione-regulated potassium exporter activity
AWQ21_RS03025	COG0860	N-Acetylmuramoyl-L-alanine amidase
AWQ21_RS03025	COG2247	cell wall binding repeat
AWQ21_RS03030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AWQ21_RS03035	COG0142	geranyltranstransferase activity
AWQ21_RS03050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ21_RS03075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ21_RS03080	COG0798	PFAM Bile acid sodium symporter
AWQ21_RS03085	COG0640	Transcriptional regulator
AWQ21_RS03095	COG0750	zinc metalloprotease
AWQ21_RS03105	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWQ21_RS03110	COG0149	triose-phosphate isomerase activity
AWQ21_RS03115	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ21_RS03115	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ21_RS03130	COG0018	arginyl-trna synthetase
AWQ21_RS03140	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AWQ21_RS03150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AWQ21_RS03160	COG0371	Dehydrogenase
AWQ21_RS03165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWQ21_RS03185	COG0284	orotidine-5'-phosphate decarboxylase activity
AWQ21_RS03185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ21_RS03190	COG1136	(ABC) transporter
AWQ21_RS03190	COG0577	efflux transmembrane transporter activity
AWQ21_RS03200	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWQ21_RS03210	COG2197	response regulator
AWQ21_RS03220	COG0251	oxidation-reduction process
AWQ21_RS03225	COG0513	Belongs to the DEAD box helicase family
AWQ21_RS03230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ21_RS03235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AWQ21_RS03240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AWQ21_RS03250	COG0483	inositol monophosphate 1-phosphatase activity
AWQ21_RS03255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ21_RS03265	COG0488	(ABC) transporter
AWQ21_RS03275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWQ21_RS03280	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AWQ21_RS03295	COG4139	cobalamin transport
AWQ21_RS03310	COG4771	TonB-dependent receptor
AWQ21_RS03315	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ21_RS03325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ21_RS03335	COG1446	asparaginase
AWQ21_RS03340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWQ21_RS03350	COG1132	(ABC) transporter
AWQ21_RS03365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AWQ21_RS03370	COG2226	methyltransferase
AWQ21_RS03385	COG0105	UTP biosynthetic process
AWQ21_RS03400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ21_RS03420	COG0515	serine threonine protein kinase
AWQ21_RS03420	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ21_RS03435	COG0189	ligase activity
AWQ21_RS03440	COG0189	ligase activity
AWQ21_RS03440	COG4067	protein conserved in archaea
AWQ21_RS03460	COG2205	protein histidine kinase activity
AWQ21_RS03460	COG0784	Response regulator, receiver
AWQ21_RS03460	COG2198	Histidine kinase
AWQ21_RS03470	COG1162	GTPase activity
AWQ21_RS03480	COG0484	heat shock protein binding
AWQ21_RS03485	COG0443	Heat shock 70 kDa protein
AWQ21_RS03490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWQ21_RS03495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWQ21_RS03505	COG1459	type II secretion system
AWQ21_RS03525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ21_RS03530	COG0596	Alpha beta hydrolase
AWQ21_RS03530	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ21_RS03545	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ21_RS03560	COG1217	gtp-binding protein TYPA
AWQ21_RS03570	COG0277	FAD linked oxidase domain protein
AWQ21_RS03575	COG1132	(ABC) transporter
AWQ21_RS03585	COG3064	Membrane
AWQ21_RS03585	COG1073	alpha beta
AWQ21_RS03585	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AWQ21_RS03590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AWQ21_RS03595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ21_RS03605	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS03615	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AWQ21_RS03630	COG1845	cytochrome c oxidase, subunit III
AWQ21_RS03640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ21_RS03655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ21_RS03670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AWQ21_RS03675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWQ21_RS03680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ21_RS03685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ21_RS03690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AWQ21_RS03695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWQ21_RS03700	COG0356	it plays a direct role in the translocation of protons across the membrane
AWQ21_RS03725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AWQ21_RS03730	COG0857	belongs to the CobB CobQ family
AWQ21_RS03740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ21_RS03750	COG0357	Ribosomal RNA small subunit methyltransferase G
AWQ21_RS03755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWQ21_RS03760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWQ21_RS03770	COG0779	Required for maturation of 30S ribosomal subunits
AWQ21_RS03775	COG0195	Participates in both transcription termination and antitermination
AWQ21_RS03785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWQ21_RS03790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AWQ21_RS03795	COG1381	Involved in DNA repair and RecF pathway recombination
AWQ21_RS03805	COG3639	organic phosphonate transmembrane transporter activity
AWQ21_RS03815	COG0515	serine threonine protein kinase
AWQ21_RS03830	COG0429	hydrolase of the alpha beta-hydrolase fold
AWQ21_RS03835	COG0488	(ABC) transporter
AWQ21_RS03845	COG0463	Glycosyl transferase, family 2
AWQ21_RS03850	COG0681	Belongs to the peptidase S26 family
AWQ21_RS03870	COG0303	'Molybdopterin
AWQ21_RS03880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AWQ21_RS03925	COG3659	wide pore channel activity
AWQ21_RS03940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ21_RS03950	COG1104	cysteine desulfurase activity
AWQ21_RS03955	COG1530	ribonuclease E activity
AWQ21_RS03960	COG3956	TIGRFAM MazG family protein
AWQ21_RS03975	COG0492	ferredoxin-NADP+ reductase activity
AWQ21_RS03980	COG0678	peroxiredoxin activity
AWQ21_RS03985	COG3273	potassium ion transport
AWQ21_RS03985	COG0471	metal ion transport
AWQ21_RS03990	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AWQ21_RS03995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AWQ21_RS04000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AWQ21_RS04005	COG4208	sulfate ABC transporter
AWQ21_RS04010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ21_RS04040	COG2226	methyltransferase
AWQ21_RS04055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ21_RS04060	COG3217	Mosc domain protein beta barrel domain protein
AWQ21_RS04060	COG0633	Ferredoxin
AWQ21_RS04080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWQ21_RS04085	COG0287	Prephenate dehydrogenase
AWQ21_RS04095	COG1022	Amp-dependent synthetase and ligase
AWQ21_RS04100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWQ21_RS04110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWQ21_RS04115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AWQ21_RS04140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ21_RS04145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AWQ21_RS04150	COG0022	dehydrogenase e1 component
AWQ21_RS04150	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWQ21_RS04165	COG0129	dihydroxy-acid dehydratase activity
AWQ21_RS04170	COG2336	PFAM SpoVT AbrB
AWQ21_RS04175	COG2337	Toxic component of a toxin-antitoxin (TA) module
AWQ21_RS04180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWQ21_RS04185	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWQ21_RS04185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWQ21_RS04205	COG1981	membrane
AWQ21_RS04210	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ21_RS04230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ21_RS04235	COG2815	serine threonine protein kinase
AWQ21_RS04235	COG0515	serine threonine protein kinase
AWQ21_RS04250	COG1012	belongs to the aldehyde dehydrogenase family
AWQ21_RS04255	COG0004	ammonium transporteR
AWQ21_RS04275	COG1185	polyribonucleotide nucleotidyltransferase activity
AWQ21_RS04280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWQ21_RS04285	COG0088	Forms part of the polypeptide exit tunnel
AWQ21_RS04290	COG0089	rRNA binding
AWQ21_RS04295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWQ21_RS04300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWQ21_RS04305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AWQ21_RS04310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWQ21_RS04315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWQ21_RS04320	COG0255	Belongs to the universal ribosomal protein uL29 family
AWQ21_RS04325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWQ21_RS04330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWQ21_RS04335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AWQ21_RS04340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWQ21_RS04345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AWQ21_RS04350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWQ21_RS04355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AWQ21_RS04360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWQ21_RS04365	COG0200	Binds to the 23S rRNA
AWQ21_RS04370	COG0201	protein transport
AWQ21_RS04375	COG0563	adenylate kinase activity
AWQ21_RS04380	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AWQ21_RS04385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWQ21_RS04390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWQ21_RS04395	COG0202	RNA polymerase activity
AWQ21_RS04400	COG0203	ribosomal protein L17
AWQ21_RS04405	COG0101	tRNA pseudouridine synthase activity
AWQ21_RS04410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWQ21_RS04415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AWQ21_RS04420	COG0254	rRNA binding
AWQ21_RS04425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWQ21_RS04435	COG3659	wide pore channel activity
AWQ21_RS04440	COG0335	large ribosomal subunit rRNA binding
AWQ21_RS04450	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AWQ21_RS04455	COG0250	Participates in transcription elongation, termination and antitermination
AWQ21_RS04460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWQ21_RS04465	COG0081	regulation of translation
AWQ21_RS04470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWQ21_RS04475	COG0222	ribosome binding
AWQ21_RS04480	COG0154	amidase activity
AWQ21_RS04485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWQ21_RS04490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ21_RS04495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWQ21_RS04525	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ21_RS04565	COG1716	ATPase activity
AWQ21_RS04590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AWQ21_RS04600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWQ21_RS04605	COG0788	formyltetrahydrofolate deformylase activity
AWQ21_RS04610	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ21_RS04620	COG0025	NhaP-type Na H and K H
AWQ21_RS04625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWQ21_RS04635	COG1429	ligase activity, forming nitrogen-metal bonds
AWQ21_RS04645	COG2361	Protein of unknown function DUF86
AWQ21_RS04665	COG0784	Response regulator, receiver
AWQ21_RS04665	COG5002	protein histidine kinase activity
AWQ21_RS04665	COG2205	protein histidine kinase activity
AWQ21_RS04680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS04695	COG0706	membrane insertase activity
AWQ21_RS04705	COG0594	ribonuclease P activity
AWQ21_RS04715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AWQ21_RS04740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ21_RS04740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ21_RS04745	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS04750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AWQ21_RS04765	COG0434	BtpA family
AWQ21_RS04770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWQ21_RS04785	COG0386	Belongs to the glutathione peroxidase family
AWQ21_RS04810	COG0166	Belongs to the GPI family
AWQ21_RS04835	COG0564	pseudouridine synthase activity
AWQ21_RS04845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWQ21_RS04850	COG0539	negative regulation of cytoplasmic translation
AWQ21_RS04855	COG1496	oxidoreductase activity
AWQ21_RS04860	COG0528	UMP kinase activity
AWQ21_RS04865	COG0233	cytoplasmic translational termination
AWQ21_RS04875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ21_RS04895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AWQ21_RS04915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWQ21_RS04925	COG2310	stress, protein
AWQ21_RS04930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AWQ21_RS04935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWQ21_RS04945	COG1702	phosphate starvation-inducible protein PhoH
AWQ21_RS04950	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS04965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWQ21_RS04985	COG0363	glucosamine-6-phosphate deaminase activity
AWQ21_RS04990	COG1716	ATPase activity
AWQ21_RS04995	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AWQ21_RS05000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS05005	COG0839	Belongs to the complex I subunit 6 family
AWQ21_RS05010	COG0713	ATP synthesis coupled electron transport
AWQ21_RS05020	COG1104	cysteine desulfurase activity
AWQ21_RS05025	COG4251	negative regulation of phosphorylation
AWQ21_RS05030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ21_RS05055	COG0489	protein tyrosine kinase activity
AWQ21_RS05065	COG2166	iron-sulfur cluster assembly
AWQ21_RS05075	COG1136	(ABC) transporter
AWQ21_RS05080	COG2954	triphosphatase activity
AWQ21_RS05085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ21_RS05095	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS05100	COG1691	(AIR) carboxylase
AWQ21_RS05110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWQ21_RS05115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS05125	COG5002	protein histidine kinase activity
AWQ21_RS05140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWQ21_RS05170	COG0045	succinate-CoA ligase (ADP-forming) activity
AWQ21_RS05180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWQ21_RS05185	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS05190	COG0561	phosphatase activity
AWQ21_RS05190	COG3100	YcgL domain-containing protein
AWQ21_RS05205	COG0540	Belongs to the ATCase OTCase family
AWQ21_RS05210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AWQ21_RS05215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWQ21_RS05220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AWQ21_RS05235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWQ21_RS05240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWQ21_RS05260	COG1357	PFAM Pentapeptide repeats (8 copies)
AWQ21_RS05265	COG0799	negative regulation of ribosome biogenesis
AWQ21_RS05275	COG3266	domain, Protein
AWQ21_RS05275	COG0515	serine threonine protein kinase
AWQ21_RS05280	COG0515	serine threonine protein kinase
AWQ21_RS05295	COG0515	serine threonine protein kinase
AWQ21_RS05295	COG3266	domain, Protein
AWQ21_RS05305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AWQ21_RS05310	COG0784	Response regulator, receiver
AWQ21_RS05310	COG2198	Histidine kinase
AWQ21_RS05310	COG5002	protein histidine kinase activity
AWQ21_RS05330	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AWQ21_RS05335	COG1116	anion transmembrane transporter activity
AWQ21_RS05340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ21_RS05345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ21_RS05350	COG3292	Two component regulator propeller
AWQ21_RS05350	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS05350	COG2205	protein histidine kinase activity
AWQ21_RS05355	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AWQ21_RS05370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ21_RS05375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ21_RS05380	COG2203	Gaf domain
AWQ21_RS05385	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS05390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AWQ21_RS05400	COG5001	Diguanylate cyclase
AWQ21_RS05400	COG3706	GGDEF domain
AWQ21_RS05400	COG2203	Gaf domain
AWQ21_RS05400	COG4251	negative regulation of phosphorylation
AWQ21_RS05410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWQ21_RS05425	COG0793	Belongs to the peptidase S41A family
AWQ21_RS05430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ21_RS05435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AWQ21_RS05455	COG2048	Heterodisulfide reductase, subunit B
AWQ21_RS05460	COG5002	protein histidine kinase activity
AWQ21_RS05465	COG0456	acetyltransferase
AWQ21_RS05475	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AWQ21_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWQ21_RS05520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AWQ21_RS05530	COG2226	methyltransferase
AWQ21_RS05535	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWQ21_RS05545	COG1196	nuclear chromosome segregation
AWQ21_RS05565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AWQ21_RS05575	COG0445	tRNA wobble uridine modification
AWQ21_RS05585	COG4251	negative regulation of phosphorylation
AWQ21_RS05605	COG0010	Belongs to the arginase family
AWQ21_RS05610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWQ21_RS05620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AWQ21_RS05650	COG2226	methyltransferase
AWQ21_RS05660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWQ21_RS05690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ21_RS05710	COG1333	cytochrome c biogenesis protein
AWQ21_RS05715	COG4399	Belongs to the UPF0754 family
AWQ21_RS05730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AWQ21_RS05740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ21_RS05750	COG2112	serine threonine protein kinase
AWQ21_RS05755	COG3688	RNA-binding protein containing a PIN domain
AWQ21_RS05790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWQ21_RS05795	COG0616	signal peptide processing
AWQ21_RS05800	COG1304	FMN binding
AWQ21_RS05805	COG0385	Bile acid
AWQ21_RS05810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWQ21_RS05830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWQ21_RS05835	COG0189	ligase activity
AWQ21_RS05850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AWQ21_RS05890	COG0561	phosphatase activity
AWQ21_RS05895	COG1982	Orn Lys Arg decarboxylase major
AWQ21_RS05900	COG0109	protoheme IX farnesyltransferase activity
AWQ21_RS05910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AWQ21_RS05915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AWQ21_RS05920	COG1845	cytochrome c oxidase, subunit III
AWQ21_RS05925	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AWQ21_RS05940	COG0629	single-stranded DNA binding
AWQ21_RS05945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ21_RS05950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AWQ21_RS05955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AWQ21_RS05970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AWQ21_RS05975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS05980	COG0668	transmembrane transport
AWQ21_RS05985	COG1361	Conserved repeat domain
AWQ21_RS05985	COG2911	Protein conserved in bacteria
AWQ21_RS05985	COG3266	domain, Protein
AWQ21_RS06000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWQ21_RS06050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AWQ21_RS06050	COG0617	tRNA 3'-terminal CCA addition
AWQ21_RS06050	COG0517	IMP dehydrogenase activity
AWQ21_RS06060	COG0426	domain, Protein
AWQ21_RS06060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ21_RS06080	COG0831	urea catabolic process
AWQ21_RS06085	COG0811	peptide transport
AWQ21_RS06090	COG0848	biopolymer transport protein
AWQ21_RS06095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AWQ21_RS06105	COG0243	molybdopterin cofactor binding
AWQ21_RS06110	COG2223	nitrite transmembrane transporter activity
AWQ21_RS06125	COG0717	Belongs to the dCTP deaminase family
AWQ21_RS06130	COG0719	Fe-S assembly protein
AWQ21_RS06130	COG1372	Participates in initiation and elongation during chromosome replication
AWQ21_RS06135	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS06155	COG0424	maF-like protein
AWQ21_RS06165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AWQ21_RS06170	COG1494	fructose-1,6-bisphosphatase
AWQ21_RS06180	COG0672	)-iron permease
AWQ21_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWQ21_RS06200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWQ21_RS06215	COG1366	Belongs to the anti-sigma-factor antagonist family
AWQ21_RS06220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWQ21_RS06230	COG0347	Belongs to the P(II) protein family
AWQ21_RS06235	COG0824	Thioesterase
AWQ21_RS06250	COG0156	8-amino-7-oxononanoate synthase activity
AWQ21_RS06255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ21_RS06255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWQ21_RS06265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWQ21_RS06270	COG0024	Methionine aminopeptidase
AWQ21_RS06280	COG0544	peptidyl-prolyl cis-trans isomerase activity
AWQ21_RS06285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AWQ21_RS06290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWQ21_RS06295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AWQ21_RS06305	COG1372	Participates in initiation and elongation during chromosome replication
AWQ21_RS06305	COG0305	Participates in initiation and elongation during chromosome replication
AWQ21_RS06305	COG1372	Participates in initiation and elongation during chromosome replication
AWQ21_RS06305	COG0305	Participates in initiation and elongation during chromosome replication
AWQ21_RS06310	COG0632	four-way junction helicase activity
AWQ21_RS06315	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWQ21_RS06345	COG0592	DNA-directed DNA polymerase activity
AWQ21_RS06355	COG0784	Response regulator, receiver
AWQ21_RS06355	COG2205	protein histidine kinase activity
AWQ21_RS06355	COG5002	protein histidine kinase activity
AWQ21_RS06365	COG0653	protein targeting
AWQ21_RS06385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ21_RS06390	COG0395	ABC-type sugar transport system, permease component
AWQ21_RS06395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AWQ21_RS06415	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ21_RS06430	COG2264	protein methyltransferase activity
AWQ21_RS06435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWQ21_RS06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AWQ21_RS06445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ21_RS06480	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AWQ21_RS06505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ21_RS06525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWQ21_RS06545	COG0805	protein transport
AWQ21_RS06580	COG0772	Belongs to the SEDS family
AWQ21_RS06590	COG0525	valine-tRNA ligase activity
AWQ21_RS06600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AWQ21_RS06620	COG1253	flavin adenine dinucleotide binding
AWQ21_RS06640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWQ21_RS06655	COG0436	Aminotransferase
AWQ21_RS06660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ21_RS06670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AWQ21_RS06680	COG0583	DNA-binding transcription factor activity
AWQ21_RS06690	COG3118	belongs to the thioredoxin family
AWQ21_RS06695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AWQ21_RS06700	COG0740	serine-type endopeptidase activity
AWQ21_RS06705	COG0740	serine-type endopeptidase activity
AWQ21_RS06710	COG1587	Uroporphyrinogen-III synthase
AWQ21_RS06720	COG0826	peptidase U32
AWQ21_RS06725	COG1192	Involved in chromosome partitioning
AWQ21_RS06770	COG0393	Putative heavy-metal-binding
AWQ21_RS06800	COG0187	DNA topoisomerase II activity
AWQ21_RS06800	COG1372	Participates in initiation and elongation during chromosome replication
AWQ21_RS06820	COG2046	Belongs to the sulfate adenylyltransferase family
AWQ21_RS06825	COG0358	DNA primase activity
AWQ21_RS06840	COG0134	indole-3-glycerol-phosphate synthase activity
AWQ21_RS06850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWQ21_RS06855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AWQ21_RS06860	COG0191	fructose-bisphosphate aldolase activity
AWQ21_RS06865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWQ21_RS06870	COG2205	protein histidine kinase activity
AWQ21_RS06875	COG5001	Diguanylate cyclase
AWQ21_RS06880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWQ21_RS06905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AWQ21_RS06910	COG0519	Catalyzes the synthesis of GMP from XMP
AWQ21_RS06910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWQ21_RS06915	COG5002	protein histidine kinase activity
AWQ21_RS06945	COG0259	pyridoxamine-phosphate oxidase activity
AWQ21_RS06950	COG0725	ABC transporter, periplasmic molybdate-binding protein
AWQ21_RS06955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ21_RS06960	COG0840	transmembrane signaling receptor activity
AWQ21_RS06970	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS06985	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
AWQ21_RS07005	COG1178	ABC-type Fe3 transport system permease component
AWQ21_RS07010	COG0784	Response regulator, receiver
AWQ21_RS07010	COG2198	Histidine kinase
AWQ21_RS07010	COG5002	protein histidine kinase activity
AWQ21_RS07020	COG5002	protein histidine kinase activity
AWQ21_RS07045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AWQ21_RS07050	COG2255	four-way junction helicase activity
AWQ21_RS07070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ21_RS07100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWQ21_RS07110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AWQ21_RS07125	COG5002	protein histidine kinase activity
AWQ21_RS07130	COG0151	Belongs to the GarS family
AWQ21_RS07135	COG0392	lysyltransferase activity
AWQ21_RS07150	COG0587	DNA-directed DNA polymerase activity
AWQ21_RS07155	COG2133	pyrroloquinoline quinone binding
AWQ21_RS07160	COG0163	prenyltransferase activity
AWQ21_RS07170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWQ21_RS07175	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AWQ21_RS07190	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AWQ21_RS07210	COG0504	CTP synthase activity
AWQ21_RS07220	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWQ21_RS07235	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AWQ21_RS07245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWQ21_RS07250	COG3536	Protein conserved in bacteria
AWQ21_RS07295	COG0681	Belongs to the peptidase S26 family
AWQ21_RS07305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AWQ21_RS07315	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AWQ21_RS07330	COG0167	dihydroorotate dehydrogenase activity
AWQ21_RS07335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AWQ21_RS07335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AWQ21_RS07335	COG1013	pyruvate-flavodoxin oxidoreductase activity
AWQ21_RS07335	COG0674	pyruvate-flavodoxin oxidoreductase activity
AWQ21_RS07350	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS07360	COG1132	(ABC) transporter
AWQ21_RS07375	COG5002	protein histidine kinase activity
AWQ21_RS07380	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS07385	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AWQ21_RS07395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ21_RS07410	COG3429	Glucose-6-phosphate dehydrogenase subunit
AWQ21_RS07410	COG3409	Peptidoglycan-binding domain 1 protein
AWQ21_RS07415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWQ21_RS07420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWQ21_RS07425	COG1566	PFAM secretion protein HlyD family protein
AWQ21_RS07430	COG0586	Pfam SNARE associated Golgi protein
AWQ21_RS07445	COG2226	methyltransferase
AWQ21_RS07450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ21_RS07450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWQ21_RS07470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AWQ21_RS07475	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AWQ21_RS07490	COG2843	Capsule synthesis protein
AWQ21_RS07500	COG0667	Aldo Keto reductase
AWQ21_RS07510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ21_RS07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ21_RS07575	COG1131	(ABC) transporter
AWQ21_RS07585	COG0842	Transport permease protein
AWQ21_RS07590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ21_RS07590	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AWQ21_RS07595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWQ21_RS07610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWQ21_RS07615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AWQ21_RS07635	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AWQ21_RS07640	COG0009	L-threonylcarbamoyladenylate synthase
AWQ21_RS07645	COG0704	Plays a role in the regulation of phosphate uptake
AWQ21_RS07655	COG0328	RNA-DNA hybrid ribonuclease activity
AWQ21_RS07665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWQ21_RS07670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWQ21_RS07685	COG2310	stress, protein
AWQ21_RS07690	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AWQ21_RS07710	COG0495	leucyl-tRNA aminoacylation
AWQ21_RS07715	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AWQ21_RS07720	COG0138	bifunctional purine biosynthesis protein purh
AWQ21_RS07725	COG0314	molybdopterin synthase activity
AWQ21_RS07730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWQ21_RS07770	COG1049	propionate catabolic process, 2-methylcitrate cycle
AWQ21_RS07775	COG0515	serine threonine protein kinase
AWQ21_RS07780	COG0116	Belongs to the methyltransferase superfamily
AWQ21_RS07815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ21_RS07820	COG0768	penicillin binding
AWQ21_RS07825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWQ21_RS07830	COG0181	hydroxymethylbilane synthase activity
AWQ21_RS07850	COG3118	belongs to the thioredoxin family
AWQ21_RS07860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWQ21_RS07870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ21_RS07880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AWQ21_RS07885	COG2346	COG2346, Truncated hemoglobins
AWQ21_RS07890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWQ21_RS07910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ21_RS07920	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ21_RS07925	COG0724	RNA recognition motif
AWQ21_RS07930	COG0174	glutamine synthetase
AWQ21_RS07940	COG0583	DNA-binding transcription factor activity
AWQ21_RS07945	COG1361	Conserved repeat domain
AWQ21_RS07945	COG2911	Protein conserved in bacteria
AWQ21_RS07945	COG3266	domain, Protein
AWQ21_RS07950	COG0107	imidazoleglycerol-phosphate synthase activity
AWQ21_RS07960	COG2247	cell wall binding repeat
AWQ21_RS07960	COG2385	sporulation resulting in formation of a cellular spore
AWQ21_RS07965	COG0643	Histidine kinase
AWQ21_RS07965	COG2198	Histidine kinase
AWQ21_RS07965	COG0784	Response regulator, receiver
AWQ21_RS07965	COG0643	Histidine kinase
AWQ21_RS07965	COG2198	Histidine kinase
AWQ21_RS07965	COG0784	Response regulator, receiver
AWQ21_RS07970	COG0217	transcriptional regulatory protein
AWQ21_RS07975	COG2205	protein histidine kinase activity
AWQ21_RS07980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AWQ21_RS07990	COG1196	nuclear chromosome segregation
AWQ21_RS07990	COG0741	lytic transglycosylase activity
AWQ21_RS07990	COG0739	heme binding
AWQ21_RS08000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AWQ21_RS08015	COG2217	Heavy metal translocating P-type atpase
AWQ21_RS08045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ21_RS08050	COG1045	serine acetyltransferase
AWQ21_RS08075	COG0735	belongs to the Fur family
AWQ21_RS08080	COG1492	cobalamin metabolic process
AWQ21_RS08090	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ21_RS08095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWQ21_RS08100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ21_RS08105	COG0442	prolyl-tRNA aminoacylation
AWQ21_RS08110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ21_RS08115	COG0469	pyruvate kinase activity
AWQ21_RS08150	COG0515	serine threonine protein kinase
AWQ21_RS08175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ21_RS08185	COG1994	Peptidase M50
AWQ21_RS08185	COG0517	IMP dehydrogenase activity
AWQ21_RS08190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWQ21_RS08200	COG4372	Transposase
AWQ21_RS08205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ21_RS08210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AWQ21_RS08215	COG0275	rRNA processing
AWQ21_RS08230	COG1192	Involved in chromosome partitioning
AWQ21_RS08270	COG2890	protein-(glutamine-N5) methyltransferase activity
AWQ21_RS08285	COG0454	-acetyltransferase
AWQ21_RS08305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AWQ21_RS08315	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ21_RS08320	COG0589	response to stress
AWQ21_RS08325	COG0126	phosphoglycerate kinase activity
AWQ21_RS08330	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ21_RS08335	COG0247	lactate metabolic process
AWQ21_RS08355	COG1515	deoxyribonuclease V activity
AWQ21_RS08365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWQ21_RS08370	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS08380	COG0628	permease
AWQ21_RS08385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ21_RS08395	COG1090	epimerase
AWQ21_RS08425	COG0457	Tetratricopeptide repeat
AWQ21_RS08430	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ21_RS08440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AWQ21_RS08445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AWQ21_RS08450	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AWQ21_RS08465	COG2084	Dehydrogenase
AWQ21_RS08480	COG0312	modulator of DNA gyrase
AWQ21_RS08485	COG0747	negative chemotaxis
AWQ21_RS08505	COG3769	mannosylglycerate metabolic process
AWQ21_RS08515	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS08535	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AWQ21_RS08565	COG0395	ABC-type sugar transport system, permease component
AWQ21_RS08570	COG1175	transmembrane transport
AWQ21_RS08575	COG1653	transport
AWQ21_RS08580	COG3842	ATPase activity
AWQ21_RS08590	COG1027	Aspartate ammonia-lyase
AWQ21_RS08595	COG3706	GGDEF domain
AWQ21_RS08600	COG0288	reversible hydration of carbon dioxide
AWQ21_RS08605	COG0411	ABC transporter
AWQ21_RS08620	COG1733	regulation of RNA biosynthetic process
AWQ21_RS08625	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AWQ21_RS08630	COG5398	heme oxygenase
AWQ21_RS08635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ21_RS08655	COG0131	Imidazoleglycerol-phosphate dehydratase
AWQ21_RS08660	COG1575	Belongs to the MenA family. Type 1 subfamily
AWQ21_RS08665	COG1666	GTP binding
AWQ21_RS08685	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ21_RS08695	COG0318	PFAM AMP-dependent synthetase and ligase
AWQ21_RS08705	COG2244	polysaccharide biosynthetic process
AWQ21_RS08715	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS08735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AWQ21_RS08740	COG0390	transport system, permease component
AWQ21_RS08750	COG0776	regulation of translation
AWQ21_RS08755	COG0628	permease
AWQ21_RS08765	COG2885	chlorophyll binding
AWQ21_RS08770	COG2885	chlorophyll binding
AWQ21_RS08775	COG0052	Belongs to the universal ribosomal protein uS2 family
AWQ21_RS08780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AWQ21_RS08785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWQ21_RS08790	COG2197	response regulator
AWQ21_RS08805	COG2205	protein histidine kinase activity
AWQ21_RS08810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWQ21_RS08830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ21_RS08835	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AWQ21_RS08870	COG0023	Translation Initiation Factor
AWQ21_RS08890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AWQ21_RS08900	COG1562	ergosterol biosynthetic process
AWQ21_RS08905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWQ21_RS08905	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AWQ21_RS08920	COG1801	Protein of unknown function DUF72
AWQ21_RS08945	COG0484	heat shock protein binding
AWQ21_RS08950	COG1191	sigma factor activity
AWQ21_RS08955	COG0037	tRNA processing
AWQ21_RS08965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AWQ21_RS08970	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AWQ21_RS08975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWQ21_RS08980	COG1799	cell septum assembly
AWQ21_RS08985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWQ21_RS08995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AWQ21_RS09025	COG3258	Cytochrome c
AWQ21_RS09030	COG0723	plastoquinol--plastocyanin reductase activity
AWQ21_RS09050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AWQ21_RS09055	COG0859	PFAM glycosyl transferase family 9
AWQ21_RS09060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AWQ21_RS09070	COG3932	Exopolysaccharide synthesis, ExoD
AWQ21_RS09075	COG0514	ATP-dependent DNA helicase (RecQ)
AWQ21_RS09085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWQ21_RS09095	COG1716	ATPase activity
AWQ21_RS09095	COG1131	(ABC) transporter
AWQ21_RS09095	COG0842	Transport permease protein
AWQ21_RS09100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AWQ21_RS09110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AWQ21_RS09120	COG2385	sporulation resulting in formation of a cellular spore
AWQ21_RS09125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWQ21_RS09135	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWQ21_RS09140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWQ21_RS09145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWQ21_RS09155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWQ21_RS09175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWQ21_RS09200	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AWQ21_RS09210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AWQ21_RS09225	COG0740	serine-type endopeptidase activity
AWQ21_RS09230	COG0194	GDP metabolic process
AWQ21_RS09235	COG2052	Domain of unknown function (DUF370)
AWQ21_RS09240	COG0793	Belongs to the peptidase S41A family
AWQ21_RS09245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ21_RS09270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AWQ21_RS09285	COG2045	Belongs to the ComB family
AWQ21_RS09295	COG0861	Integral membrane protein TerC family
AWQ21_RS09300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ21_RS09310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AWQ21_RS09315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWQ21_RS09320	COG0408	coproporphyrinogen oxidase activity
AWQ21_RS09330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ21_RS09330	COG2022	thiamine diphosphate biosynthetic process
AWQ21_RS09335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWQ21_RS09345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWQ21_RS09365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ21_RS09370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWQ21_RS09380	COG0719	Fe-S assembly protein
AWQ21_RS09385	COG0396	ATPase activity
AWQ21_RS09390	COG0719	Fe-S assembly protein
AWQ21_RS09395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ21_RS09405	COG1166	arginine decarboxylase activity
AWQ21_RS09415	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS09420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AWQ21_RS09425	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS09430	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS09435	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AWQ21_RS09440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWQ21_RS09440	COG4451	ribulose bisphosphate carboxylase, small
AWQ21_RS09445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AWQ21_RS09450	COG1850	ribulose-bisphosphate carboxylase activity
AWQ21_RS09505	COG1489	DNA binding
AWQ21_RS09510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWQ21_RS09510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ21_RS09515	COG2226	methyltransferase
AWQ21_RS09520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWQ21_RS09545	COG0582	viral genome integration into host DNA
AWQ21_RS09565	COG1396	sequence-specific DNA binding
AWQ21_RS09660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ21_RS09670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AWQ21_RS09675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWQ21_RS09680	COG0512	Glutamine amidotransferase of anthranilate synthase
AWQ21_RS09680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ21_RS09685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWQ21_RS09705	COG0170	dolichyl monophosphate biosynthetic process
AWQ21_RS09710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWQ21_RS09725	COG0113	porphobilinogen synthase activity
AWQ21_RS09735	COG0010	Belongs to the arginase family
AWQ21_RS09740	COG1116	anion transmembrane transporter activity
AWQ21_RS09745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AWQ21_RS09755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ21_RS09760	COG0375	protein maturation
AWQ21_RS09770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AWQ21_RS09775	COG0426	domain, Protein
AWQ21_RS09775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWQ21_RS09780	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AWQ21_RS09785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AWQ21_RS09790	COG3174	membrane
AWQ21_RS09795	COG0484	heat shock protein binding
AWQ21_RS09800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWQ21_RS09800	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWQ21_RS09815	COG1121	(ABC) transporter
AWQ21_RS09820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ21_RS09830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWQ21_RS09840	COG0012	GTP binding
AWQ21_RS09845	COG2815	serine threonine protein kinase
AWQ21_RS09845	COG0515	serine threonine protein kinase
AWQ21_RS09855	COG2267	carboxylic ester hydrolase activity
AWQ21_RS09880	COG0095	Lipoate-protein ligase
AWQ21_RS09900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWQ21_RS09920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWQ21_RS09925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AWQ21_RS09925	COG0237	dephospho-CoA kinase activity
AWQ21_RS09945	COG1971	Probably functions as a manganese efflux pump
AWQ21_RS09955	COG1420	regulation of RNA biosynthetic process
AWQ21_RS09960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ21_RS09965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS09975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ21_RS09980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWQ21_RS09985	COG0085	RNA polymerase activity
AWQ21_RS09990	COG0084	hydrolase, TatD family'
AWQ21_RS09995	COG0268	Binds directly to 16S ribosomal RNA
AWQ21_RS10000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWQ21_RS10045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWQ21_RS10055	COG0051	transcription antitermination factor activity, RNA binding
AWQ21_RS10060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWQ21_RS10065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ21_RS10070	COG0049	tRNA binding
AWQ21_RS10075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWQ21_RS10080	COG0316	Belongs to the HesB IscA family
AWQ21_RS10095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWQ21_RS10145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWQ21_RS10155	COG0529	Catalyzes the synthesis of activated sulfate
AWQ21_RS10160	COG0617	tRNA 3'-terminal CCA addition
AWQ21_RS10165	COG1054	Belongs to the UPF0176 family
AWQ21_RS10170	COG0175	sulfate reduction
AWQ21_RS10175	COG0359	binds to the 23S rRNA
AWQ21_RS10180	COG2199	diguanylate cyclase activity
AWQ21_RS10185	COG0489	protein tyrosine kinase activity
AWQ21_RS10270	COG2226	methyltransferase
AWQ21_RS10275	COG0535	radical SAM domain protein
AWQ21_RS10280	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS10330	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS10340	COG0297	glycogen (starch) synthase activity
AWQ21_RS10355	COG0297	glycogen (starch) synthase activity
AWQ21_RS10360	COG0463	Glycosyl transferase, family 2
AWQ21_RS10380	COG2171	N-acyltransferase activity
AWQ21_RS10385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWQ21_RS10395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWQ21_RS10410	COG1077	Cell shape determining protein MreB Mrl
AWQ21_RS10435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AWQ21_RS10440	COG0297	glycogen (starch) synthase activity
AWQ21_RS10450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AWQ21_RS10455	COG0740	serine-type endopeptidase activity
AWQ21_RS10495	COG0557	exoribonuclease II activity
AWQ21_RS10505	COG0047	phosphoribosylformylglycinamidine synthase activity
AWQ21_RS10510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWQ21_RS10515	COG0701	Predicted permease
AWQ21_RS10525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ21_RS10525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWQ21_RS10555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWQ21_RS10560	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWQ21_RS10565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AWQ21_RS10575	COG1597	lipid kinase activity
AWQ21_RS10585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ21_RS10595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AWQ21_RS10605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWQ21_RS10625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ21_RS10645	COG4149	molybdate abc transporter
AWQ21_RS10655	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AWQ21_RS10670	COG0039	L-malate dehydrogenase activity
AWQ21_RS10690	COG0418	dihydroorotase activity
AWQ21_RS10705	COG5002	protein histidine kinase activity
AWQ21_RS10715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AWQ21_RS10720	COG0210	DNA helicase
AWQ21_RS10725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AWQ21_RS10730	COG4555	ABC transporter
AWQ21_RS10735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWQ21_RS10750	COG1595	DNA-templated transcription, initiation
AWQ21_RS10770	COG1252	NADH dehydrogenase
AWQ21_RS10780	COG0829	nickel cation binding
AWQ21_RS10790	COG0297	glycogen (starch) synthase activity
AWQ21_RS10800	COG0439	Biotin carboxylase
AWQ21_RS10820	COG0460	homoserine dehydrogenase
AWQ21_RS10840	COG4636	protein conserved in cyanobacteria
AWQ21_RS10890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWQ21_RS10895	COG0601	transmembrane transport
AWQ21_RS10900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWQ21_RS10905	COG0589	response to stress
AWQ21_RS10940	COG4636	protein conserved in cyanobacteria
AWQ21_RS10955	COG0443	Heat shock 70 kDa protein
AWQ21_RS10960	COG0484	heat shock protein binding
AWQ21_RS10965	COG0564	pseudouridine synthase activity
AWQ21_RS10970	COG0668	transmembrane transport
AWQ21_RS11045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AWQ21_RS11050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AWQ21_RS11070	COG0463	Glycosyl transferase, family 2
AWQ21_RS11075	COG0003	Pfam Anion-transporting ATPase
AWQ21_RS11085	COG0436	Aminotransferase
AWQ21_RS11090	COG1132	(ABC) transporter
AWQ21_RS11100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWQ21_RS11110	COG0167	dihydroorotate dehydrogenase activity
AWQ21_RS11115	COG0772	Belongs to the SEDS family
AWQ21_RS11120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AWQ21_RS11150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWQ21_RS11165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AWQ21_RS11175	COG0004	ammonium transporteR
AWQ21_RS11190	COG0237	dephospho-CoA kinase activity
AWQ21_RS11195	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWQ21_RS11200	COG1413	lyase activity
AWQ21_RS11205	COG1413	lyase activity
AWQ21_RS11210	COG1401	restriction endodeoxyribonuclease activity
AWQ21_RS11220	COG1748	Saccharopine dehydrogenase
AWQ21_RS11225	COG0824	Thioesterase
AWQ21_RS11235	COG0537	adenosine 5'-monophosphoramidase activity
AWQ21_RS11245	COG1131	(ABC) transporter
AWQ21_RS11275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AWQ21_RS11280	COG1131	(ABC) transporter
AWQ21_RS11295	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AWQ21_RS11325	COG1192	Involved in chromosome partitioning
AWQ21_RS11365	COG0193	aminoacyl-tRNA hydrolase activity
AWQ21_RS11385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWQ21_RS11390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWQ21_RS11420	COG0419	ATPase involved in DNA repair
AWQ21_RS11430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWQ21_RS11440	COG0372	Belongs to the citrate synthase family
AWQ21_RS11445	COG2062	phosphohistidine phosphatase, SixA
AWQ21_RS11475	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWQ21_RS11480	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS11485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS11495	COG2217	Heavy metal translocating P-type atpase
AWQ21_RS11520	COG3693	PFAM glycoside hydrolase, family 10
AWQ21_RS11525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AWQ21_RS11530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ21_RS11535	COG0784	Response regulator, receiver
AWQ21_RS11550	COG0840	transmembrane signaling receptor activity
AWQ21_RS11550	COG2203	Gaf domain
AWQ21_RS11555	COG0643	Histidine kinase
AWQ21_RS11555	COG2198	Histidine kinase
AWQ21_RS11560	COG0484	heat shock protein binding
AWQ21_RS11570	COG0259	pyridoxamine-phosphate oxidase activity
AWQ21_RS11575	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ21_RS11575	COG3347	Dehydrogenase
AWQ21_RS11580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWQ21_RS11585	COG3300	MHYT domain
AWQ21_RS11585	COG5001	Diguanylate cyclase
AWQ21_RS11600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AWQ21_RS11615	COG1193	negative regulation of DNA recombination
AWQ21_RS11620	COG2373	Large extracellular alpha-helical protein
AWQ21_RS11625	COG3854	ATPases associated with a variety of cellular activities
AWQ21_RS11635	COG1053	succinate dehydrogenase
AWQ21_RS11655	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AWQ21_RS11660	COG0640	Transcriptional regulator
AWQ21_RS11670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWQ21_RS11675	COG0406	alpha-ribazole phosphatase activity
AWQ21_RS11680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWQ21_RS11690	COG2211	Major facilitator Superfamily
AWQ21_RS11715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWQ21_RS11725	COG0601	transmembrane transport
AWQ21_RS11730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWQ21_RS11740	COG1007	ATP synthesis coupled electron transport
AWQ21_RS11745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWQ21_RS11745	COG1754	DNA topoisomerase type I activity
AWQ21_RS11750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AWQ21_RS11760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWQ21_RS11765	COG0571	ribonuclease III activity
AWQ21_RS11770	COG0649	NAD binding
AWQ21_RS11780	COG0697	spore germination
AWQ21_RS11785	COG0616	signal peptide processing
AWQ21_RS11800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWQ21_RS11810	COG0745	RESPONSE REGULATOR receiver
AWQ21_RS11840	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AWQ21_RS11845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AWQ21_RS11855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AWQ21_RS11860	COG1058	Belongs to the CinA family
AWQ21_RS11860	COG1546	Belongs to the CinA family
AWQ21_RS11870	COG2197	response regulator
AWQ21_RS11875	COG3411	Ferredoxin
AWQ21_RS11890	COG0300	oxidoreductase activity
AWQ21_RS11890	COG3000	fatty acid hydroxylase
AWQ21_RS11900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AWQ21_RS11905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWQ21_RS11910	COG1690	Belongs to the RtcB family
AWQ21_RS11915	COG0484	heat shock protein binding
AWQ21_RS11930	COG2268	Band 7 protein
AWQ21_RS11940	COG5398	heme oxygenase
AWQ21_RS11950	COG0531	amino acid
AWQ21_RS11955	COG1840	ABC-type Fe3 transport system, periplasmic component
AWQ21_RS11960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ21_RS11960	COG0758	DNA mediated transformation
AWQ21_RS11965	COG0505	Belongs to the CarA family
AWQ21_RS11970	COG5002	protein histidine kinase activity
AWQ21_RS11975	COG3063	Type IV pilus biogenesis stability protein PilW
AWQ21_RS11985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AWQ21_RS11990	COG1121	(ABC) transporter
AWQ21_RS11995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWQ21_RS12010	COG0432	Pfam Uncharacterised protein family UPF0047
AWQ21_RS12020	COG0612	Peptidase, M16
AWQ21_RS12045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AWQ21_RS12050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWQ21_RS12055	COG0165	Argininosuccinate lyase
AWQ21_RS12125	COG0575	Belongs to the CDS family
AWQ21_RS12135	COG0644	oxidoreductase
AWQ21_RS12150	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS12160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWQ21_RS12175	COG0431	NADPH-dependent FMN reductase
AWQ21_RS12190	COG0017	Asparaginyl-tRNA synthetase
AWQ21_RS12200	COG0646	methionine synthase
AWQ21_RS12200	COG1410	methionine synthase
AWQ21_RS12210	COG1331	Highly conserved protein containing a thioredoxin domain
AWQ21_RS12220	COG5001	Diguanylate cyclase
AWQ21_RS12230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AWQ21_RS12245	COG0459	protein refolding
AWQ21_RS12250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AWQ21_RS12255	COG0751	glycine-tRNA ligase activity
AWQ21_RS12260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWQ21_RS12295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWQ21_RS12310	COG1902	pentaerythritol trinitrate reductase activity
AWQ21_RS12315	COG0302	gtp cyclohydrolase
AWQ21_RS12320	COG0825	malonyl-CoA metabolic process
AWQ21_RS12325	COG0670	Belongs to the BI1 family
AWQ21_RS12330	COG1309	transcriptional regulator
AWQ21_RS12340	COG1940	carbohydrate kinase activity
AWQ21_RS12345	COG0832	Belongs to the urease beta subunit family
AWQ21_RS12360	COG0438	transferase activity, transferring glycosyl groups
AWQ21_RS12375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWQ21_RS12380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWQ21_RS12390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWQ21_RS12405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AWQ21_RS12410	COG0659	secondary active sulfate transmembrane transporter activity
AWQ21_RS12415	COG0589	response to stress
AWQ21_RS12420	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AWQ21_RS12425	COG0481	GTPase activity
AWQ21_RS12440	COG0443	Heat shock 70 kDa protein
AWQ21_RS12455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AWQ21_RS12470	COG0435	Glutathione S-transferase
AWQ21_RS12485	COG1480	7TM receptor with intracellular HD hydrolase
AWQ21_RS12495	COG0336	Belongs to the RNA methyltransferase TrmD family
AWQ21_RS12505	COG1181	Belongs to the D-alanine--D-alanine ligase family
AWQ21_RS12505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AWQ21_RS12510	COG0077	Prephenate dehydratase
AWQ21_RS12510	COG1605	Chorismate mutase
AWQ21_RS12520	COG1473	amidohydrolase
AWQ21_RS12535	COG0714	Associated with various cellular activities
AWQ21_RS12540	COG0196	riboflavin kinase activity
AWQ21_RS12545	COG1234	tRNA 3'-trailer cleavage
AWQ21_RS12560	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AWQ21_RS12565	COG0069	glutamate synthase activity
AWQ21_RS12565	COG0067	glutamate synthase
AWQ21_RS12565	COG0070	glutamate synthase
AWQ21_RS12575	COG2010	Cytochrome c
AWQ21_RS12585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AWQ21_RS12600	COG1187	pseudouridine synthase activity
AWQ21_RS12610	COG0587	DNA-directed DNA polymerase activity
AWQ21_RS12615	COG1051	belongs to the nudix hydrolase family
AWQ21_RS12615	COG1056	cytidyltransferase-related domain
AWQ21_RS12620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AWQ21_RS12655	COG0651	ATP synthesis coupled electron transport
AWQ21_RS12660	COG0651	ATP synthesis coupled electron transport
AWQ21_RS12665	COG1006	Multisubunit Na H antiporter MnhC subunit
AWQ21_RS12670	COG0475	glutathione-regulated potassium exporter activity
AWQ21_RS12675	COG0659	secondary active sulfate transmembrane transporter activity
AWQ21_RS12680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AWQ21_RS12690	COG3118	belongs to the thioredoxin family
AWQ21_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
AWQ21_RS12700	COG0500	methyltransferase
AWQ21_RS12705	COG5002	protein histidine kinase activity
AWQ21_RS12710	COG5001	Diguanylate cyclase
AWQ21_RS12710	COG4251	negative regulation of phosphorylation
AWQ21_RS12710	COG3706	GGDEF domain
AWQ21_RS12710	COG2203	Gaf domain
AWQ21_RS12715	COG0539	negative regulation of cytoplasmic translation
AWQ21_RS12725	COG2226	methyltransferase
AWQ21_RS12730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWQ21_RS12730	COG2022	thiamine diphosphate biosynthetic process
AWQ21_RS12735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AWQ21_RS12745	COG1187	pseudouridine synthase activity
AWQ21_RS12755	COG2081	HI0933 family
AWQ21_RS12765	COG0473	3-isopropylmalate dehydrogenase activity
AWQ21_RS12770	COG0542	response to heat
AWQ21_RS12775	COG4115	mRNA cleavage
AWQ21_RS12780	COG2161	toxin-antitoxin pair type II binding
AWQ21_RS12805	COG0242	peptide deformylase activity
AWQ21_RS12810	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AWQ21_RS12820	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AWQ21_RS12835	COG0024	Methionine aminopeptidase
AWQ21_RS12850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AWQ21_RS12865	COG0792	nuclease activity
AWQ21_RS12885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWQ21_RS12900	COG0830	nickel cation binding
AWQ21_RS12905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWQ21_RS12910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS12915	COG0633	Ferredoxin
AWQ21_RS12925	COG0673	inositol 2-dehydrogenase activity
AWQ21_RS12940	COG1836	PFAM Integral membrane protein DUF92
AWQ21_RS12950	COG2132	Multicopper oxidase
AWQ21_RS12955	COG2217	Heavy metal translocating P-type atpase
AWQ21_RS12990	COG1252	NADH dehydrogenase
AWQ21_RS12995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWQ21_RS13005	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWQ21_RS13025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWQ21_RS13030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AWQ21_RS13040	COG0768	penicillin binding
AWQ21_RS13050	COG3046	protein related to deoxyribodipyrimidine photolyase
AWQ21_RS13060	COG3152	Membrane
AWQ21_RS13065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWQ21_RS13075	COG0315	cyclic pyranopterin monophosphate synthase activity
AWQ21_RS13090	COG0802	atpase or kinase
AWQ21_RS13100	COG0581	inorganic phosphate transmembrane transporter activity
AWQ21_RS13105	COG0573	inorganic phosphate transmembrane transporter activity
AWQ21_RS13110	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AWQ21_RS13115	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AWQ21_RS13125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AWQ21_RS13130	COG2267	carboxylic ester hydrolase activity
AWQ21_RS13145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AWQ21_RS13155	COG0124	histidyl-tRNA synthetase
AWQ21_RS13175	COG3437	response regulator, receiver
AWQ21_RS13175	COG3850	Histidine kinase
AWQ21_RS13175	COG4999	Histidine kinase
AWQ21_RS13175	COG2205	protein histidine kinase activity
AWQ21_RS13190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWQ21_RS13195	COG0569	domain protein
AWQ21_RS13200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AWQ21_RS13245	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AWQ21_RS13250	COG0556	nucleotide-excision repair
AWQ21_RS13260	COG0454	-acetyltransferase
AWQ21_RS13320	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AWQ21_RS13350	COG4948	Mandelate Racemase Muconate Lactonizing
AWQ21_RS13360	COG2205	protein histidine kinase activity
AWQ21_RS13360	COG3850	Histidine kinase
AWQ21_RS13360	COG3437	response regulator, receiver
AWQ21_RS13360	COG4999	Histidine kinase
AWQ21_RS13375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AWQ21_RS13410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWQ21_RS13415	COG2200	EAL domain
AWQ21_RS13420	COG0523	cobalamin synthesis protein
AWQ21_RS13430	COG3659	wide pore channel activity
AWQ21_RS13435	COG3128	pkhd-type hydroxylase
AWQ21_RS13460	COG2193	ferroxidase activity
AWQ21_RS13465	COG0572	uridine kinase
AWQ21_RS13475	COG0415	Belongs to the DNA photolyase family
AWQ21_RS13480	COG0596	Alpha beta hydrolase
AWQ21_RS13515	COG2319	Wd-40 repeat
AWQ21_RS13515	COG4249	Peptidase C14 caspase catalytic subunit p20
AWQ21_RS13560	COG0709	Synthesizes selenophosphate from selenide and ATP
AWQ21_RS13565	COG2202	Pas domain
AWQ21_RS13565	COG2205	protein histidine kinase activity
AWQ21_RS13580	COG3012	SEC-C Motif Domain Protein
AWQ21_RS13595	COG2226	methyltransferase
AWQ21_RS13600	COG0668	transmembrane transport
AWQ21_RS13615	COG0515	serine threonine protein kinase
AWQ21_RS13615	COG3266	domain, Protein
AWQ21_RS13645	COG1122	ATPase activity
AWQ21_RS13650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AWQ21_RS13655	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWQ21_RS13670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AWQ21_RS13690	COG1741	Belongs to the pirin family
AWQ21_RS13715	COG0237	dephospho-CoA kinase activity
AWQ21_RS13730	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWQ21_RS13735	COG0482	sulfurtransferase activity
AWQ21_RS13750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWQ21_RS13755	COG0440	acetolactate synthase activity
AWQ21_RS13760	COG2267	carboxylic ester hydrolase activity
AWQ21_RS13765	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AWQ21_RS13785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWQ21_RS13790	COG0330	HflC and HflK could
AWQ21_RS13795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWQ21_RS13805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWQ21_RS13810	COG1672	PFAM Archaeal ATPase
AWQ21_RS13815	COG0589	response to stress
AWQ21_RS13825	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS13830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS13835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWQ21_RS13840	COG2319	Wd-40 repeat
AWQ21_RS13845	COG3659	wide pore channel activity
AWQ21_RS13860	COG0004	ammonium transporteR
AWQ21_RS13865	COG3239	Fatty acid desaturase
AWQ21_RS13875	COG2119	membrane
AWQ21_RS13890	COG1473	amidohydrolase
AWQ21_RS13900	COG3300	MHYT domain
AWQ21_RS13900	COG5001	Diguanylate cyclase
AWQ21_RS13905	COG2304	oxidoreductase activity
AWQ21_RS13910	COG2501	S4 domain
AWQ21_RS13915	COG0412	Dienelactone hydrolase
AWQ21_RS13930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AWQ21_RS13935	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AWQ21_RS13940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWQ21_RS13950	COG1012	belongs to the aldehyde dehydrogenase family
AWQ21_RS13970	COG0686	Belongs to the AlaDH PNT family
AWQ21_RS13975	COG0582	viral genome integration into host DNA
AWQ21_RS13990	COG0625	glutathione transferase activity
AWQ21_RS14000	COG0343	queuine tRNA-ribosyltransferase activity
AWQ21_RS14010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AWQ21_RS14045	COG1132	(ABC) transporter
AWQ21_RS14050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWQ21_RS14055	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWQ21_RS14065	COG0552	protein localization to endoplasmic reticulum
AWQ21_RS14075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AWQ21_RS14080	COG0415	Belongs to the DNA photolyase family
AWQ21_RS14105	COG4968	Prepilin-type N-terminal cleavage methylation domain
AWQ21_RS14110	COG2852	Protein conserved in bacteria
AWQ21_RS14115	COG0137	argininosuccinate synthase activity
AWQ21_RS14120	COG1234	tRNA 3'-trailer cleavage
AWQ21_RS14140	COG0312	modulator of DNA gyrase
AWQ21_RS14145	COG2154	pterin-4-alpha-carbinolamine dehydratase
AWQ21_RS14150	COG3659	wide pore channel activity
AWQ21_RS14155	COG2084	Dehydrogenase
AWQ21_RS14160	COG5001	Diguanylate cyclase
AWQ21_RS14160	COG4251	negative regulation of phosphorylation
AWQ21_RS14160	COG3706	GGDEF domain
AWQ21_RS14160	COG2203	Gaf domain
AWQ21_RS14165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AWQ21_RS14175	COG2205	protein histidine kinase activity
AWQ21_RS14180	COG1543	Belongs to the glycosyl hydrolase 57 family
AWQ21_RS14190	COG1950	PFAM Membrane protein of
AWQ21_RS14200	COG3339	Conserved Protein
AWQ21_RS14215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWQ21_RS14220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWQ21_RS14235	COG4956	integral membrane protein (PIN domain superfamily)
AWQ21_RS14240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AWQ21_RS14245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWQ21_RS14260	COG4251	negative regulation of phosphorylation
AWQ21_RS14290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWQ21_RS14310	COG2211	Major facilitator Superfamily
AWQ21_RS14340	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AWQ21_RS14345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWQ21_RS14350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWQ21_RS14355	COG0135	phosphoribosylanthranilate isomerase activity
AWQ21_RS14360	COG0746	molybdenum cofactor guanylyltransferase activity
AWQ21_RS14370	COG3954	Phosphoribulokinase
AWQ21_RS14375	COG0277	FAD linked oxidase domain protein
AWQ21_RS14400	COG4251	negative regulation of phosphorylation
AWQ21_RS14400	COG5001	Diguanylate cyclase
AWQ21_RS14400	COG2203	Gaf domain
AWQ21_RS14400	COG3706	GGDEF domain
AWQ21_RS14405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWQ21_RS14410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWQ21_RS14415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWQ21_RS14420	COG0730	response to heat
AWQ21_RS14440	COG2304	oxidoreductase activity
AWQ21_RS14445	COG0215	cysteine-tRNA ligase activity
AWQ21_RS14455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ21_RS14640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AWQ21_RS14865	COG0840	transmembrane signaling receptor activity
AWQ21_RS14865	COG2203	Gaf domain
AWQ21_RS14875	COG0840	transmembrane signaling receptor activity
AWQ21_RS14875	COG2203	Gaf domain
AWQ21_RS15215	COG2116	formate transmembrane transporter activity
AWQ21_RS15430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient