locus-tag	class	description
SYN7502_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SYN7502_RS00010	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
SYN7502_RS00015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SYN7502_RS00025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYN7502_RS00045	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SYN7502_RS00065	COG0601	transmembrane transport
SYN7502_RS00070	COG0151	Belongs to the GarS family
SYN7502_RS00080	COG0495	leucyl-tRNA aminoacylation
SYN7502_RS00090	COG0587	DNA-directed DNA polymerase activity
SYN7502_RS00095	COG0746	molybdenum cofactor guanylyltransferase activity
SYN7502_RS00100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SYN7502_RS00105	COG0581	inorganic phosphate transmembrane transporter activity
SYN7502_RS00110	COG0573	inorganic phosphate transmembrane transporter activity
SYN7502_RS00115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYN7502_RS00120	COG0850	regulation of cytokinetic process
SYN7502_RS00125	COG0542	response to heat
SYN7502_RS00140	COG0737	Belongs to the 5'-nucleotidase family
SYN7502_RS00140	COG1525	nuclease
SYN7502_RS00140	COG4085	toxin activity
SYN7502_RS00155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYN7502_RS00155	COG2022	thiamine diphosphate biosynthetic process
SYN7502_RS00160	COG0681	Belongs to the peptidase S26 family
SYN7502_RS00180	COG0121	glutamine amidotransferase
SYN7502_RS00185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SYN7502_RS00195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYN7502_RS00200	COG0434	BtpA family
SYN7502_RS00210	COG3937	granule-associated protein
SYN7502_RS00220	COG0708	Exodeoxyribonuclease III
SYN7502_RS00225	COG2770	Histidine kinase
SYN7502_RS00225	COG2208	phosphoserine phosphatase activity
SYN7502_RS00250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SYN7502_RS00255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYN7502_RS00275	COG1187	pseudouridine synthase activity
SYN7502_RS00290	COG0494	nUDIX hydrolase
SYN7502_RS00295	COG2048	Heterodisulfide reductase, subunit B
SYN7502_RS00305	COG1192	Involved in chromosome partitioning
SYN7502_RS00335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SYN7502_RS00340	COG4658	electron transport chain
SYN7502_RS00355	COG0084	hydrolase, TatD family'
SYN7502_RS00360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SYN7502_RS00375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SYN7502_RS00385	COG2095	MarC family integral membrane protein
SYN7502_RS00390	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SYN7502_RS00395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS00400	COG0583	DNA-binding transcription factor activity
SYN7502_RS00405	COG0640	Transcriptional regulator
SYN7502_RS00415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYN7502_RS00420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYN7502_RS00430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYN7502_RS00440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SYN7502_RS00440	COG0574	Belongs to the PEP-utilizing enzyme family
SYN7502_RS00445	COG0243	molybdopterin cofactor binding
SYN7502_RS00450	COG1116	anion transmembrane transporter activity
SYN7502_RS00450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS00455	COG1116	anion transmembrane transporter activity
SYN7502_RS00460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYN7502_RS00465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS00475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SYN7502_RS00480	COG0287	Prephenate dehydrogenase
SYN7502_RS00520	COG3239	Fatty acid desaturase
SYN7502_RS00525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SYN7502_RS00530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SYN7502_RS00545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SYN7502_RS00570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SYN7502_RS00575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SYN7502_RS00600	COG0792	nuclease activity
SYN7502_RS00615	COG3239	Fatty acid desaturase
SYN7502_RS00620	COG1218	3'(2'),5'-bisphosphate nucleotidase
SYN7502_RS00625	COG4597	amino acid ABC transporter
SYN7502_RS00630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SYN7502_RS00635	COG0396	ATPase activity
SYN7502_RS00640	COG0719	Fe-S assembly protein
SYN7502_RS00655	COG0768	penicillin binding
SYN7502_RS00660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SYN7502_RS00665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SYN7502_RS00730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SYN7502_RS00770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SYN7502_RS00775	COG0456	acetyltransferase
SYN7502_RS00780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SYN7502_RS00785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SYN7502_RS00790	COG1054	Belongs to the UPF0176 family
SYN7502_RS00795	COG4172	Belongs to the ABC transporter superfamily
SYN7502_RS00830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SYN7502_RS00840	COG0242	peptide deformylase activity
SYN7502_RS00850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYN7502_RS00860	COG0105	UTP biosynthetic process
SYN7502_RS00870	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SYN7502_RS00885	COG0672	)-iron permease
SYN7502_RS00895	COG1193	negative regulation of DNA recombination
SYN7502_RS00925	COG0628	permease
SYN7502_RS00930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYN7502_RS00940	COG1160	GTP binding
SYN7502_RS00970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SYN7502_RS00975	COG0193	aminoacyl-tRNA hydrolase activity
SYN7502_RS00985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYN7502_RS01000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS01005	COG0129	dihydroxy-acid dehydratase activity
SYN7502_RS01010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYN7502_RS01040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYN7502_RS01050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SYN7502_RS01055	COG0569	domain protein
SYN7502_RS01060	COG0237	dephospho-CoA kinase activity
SYN7502_RS01060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYN7502_RS01075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SYN7502_RS01085	COG1834	amidinotransferase
SYN7502_RS01090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SYN7502_RS01095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SYN7502_RS01100	COG1799	cell septum assembly
SYN7502_RS01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SYN7502_RS01110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SYN7502_RS01125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SYN7502_RS01130	COG0606	chelatase, subunit chli
SYN7502_RS01135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SYN7502_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
SYN7502_RS01145	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYN7502_RS01155	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SYN7502_RS01160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SYN7502_RS01165	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SYN7502_RS01170	COG4208	sulfate ABC transporter
SYN7502_RS01185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS01190	COG3659	wide pore channel activity
SYN7502_RS01195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYN7502_RS01200	COG1116	anion transmembrane transporter activity
SYN7502_RS01200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS01205	COG1116	anion transmembrane transporter activity
SYN7502_RS01220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SYN7502_RS01230	COG0402	S-adenosylhomocysteine deaminase activity
SYN7502_RS01245	COG0697	spore germination
SYN7502_RS01250	COG2010	Cytochrome c
SYN7502_RS01255	COG0039	L-malate dehydrogenase activity
SYN7502_RS01260	COG0791	NLP P60 protein
SYN7502_RS01270	COG1032	radical SAM domain protein
SYN7502_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
SYN7502_RS01290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SYN7502_RS01295	COG0189	ligase activity
SYN7502_RS01295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SYN7502_RS01305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYN7502_RS01310	COG0564	pseudouridine synthase activity
SYN7502_RS01320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SYN7502_RS01325	COG0022	dehydrogenase e1 component
SYN7502_RS01325	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYN7502_RS01340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYN7502_RS01345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS01350	COG0038	chloride channel
SYN7502_RS01360	COG0025	NhaP-type Na H and K H
SYN7502_RS01365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SYN7502_RS01370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYN7502_RS01400	COG0515	serine threonine protein kinase
SYN7502_RS01415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYN7502_RS01425	COG0799	negative regulation of ribosome biogenesis
SYN7502_RS01435	COG1131	(ABC) transporter
SYN7502_RS01445	COG0488	(ABC) transporter
SYN7502_RS01455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYN7502_RS01470	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS01515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SYN7502_RS01525	COG0126	phosphoglycerate kinase activity
SYN7502_RS01530	COG3266	domain, Protein
SYN7502_RS01530	COG0515	serine threonine protein kinase
SYN7502_RS01545	COG2204	response regulator
SYN7502_RS01550	COG0586	Pfam SNARE associated Golgi protein
SYN7502_RS01635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SYN7502_RS01660	COG2020	methyltransferase activity
SYN7502_RS01680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SYN7502_RS01685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SYN7502_RS01695	COG0681	Belongs to the peptidase S26 family
SYN7502_RS01705	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS01730	COG0776	regulation of translation
SYN7502_RS01745	COG2203	Gaf domain
SYN7502_RS01745	COG3706	GGDEF domain
SYN7502_RS01745	COG4251	negative regulation of phosphorylation
SYN7502_RS01745	COG5001	Diguanylate cyclase
SYN7502_RS01750	COG5002	protein histidine kinase activity
SYN7502_RS01750	COG2198	Histidine kinase
SYN7502_RS01750	COG0784	Response regulator, receiver
SYN7502_RS01755	COG5001	Diguanylate cyclase
SYN7502_RS01770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SYN7502_RS01775	COG0371	Dehydrogenase
SYN7502_RS01780	COG5398	heme oxygenase
SYN7502_RS01785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS01790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS01795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS01810	COG2211	Major facilitator Superfamily
SYN7502_RS01825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SYN7502_RS01855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SYN7502_RS01875	COG3659	wide pore channel activity
SYN7502_RS01895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SYN7502_RS01915	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SYN7502_RS01920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SYN7502_RS01925	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SYN7502_RS01930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SYN7502_RS01940	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS01945	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS01950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SYN7502_RS01955	COG3878	Protein conserved in bacteria
SYN7502_RS01975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SYN7502_RS02000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SYN7502_RS02005	COG1420	regulation of RNA biosynthetic process
SYN7502_RS02015	COG0751	glycine-tRNA ligase activity
SYN7502_RS02035	COG0012	GTP binding
SYN7502_RS02040	COG1752	Esterase of the alpha-beta hydrolase superfamily
SYN7502_RS02050	COG0436	Aminotransferase
SYN7502_RS02075	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYN7502_RS02080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SYN7502_RS02085	COG5398	heme oxygenase
SYN7502_RS02090	COG0789	Transcriptional regulator
SYN7502_RS02095	COG0604	alcohol dehydrogenase
SYN7502_RS02105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SYN7502_RS02110	COG1215	transferase activity, transferring glycosyl groups
SYN7502_RS02120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SYN7502_RS02125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SYN7502_RS02130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SYN7502_RS02140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS02170	COG0601	transmembrane transport
SYN7502_RS02180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SYN7502_RS02195	COG2337	Toxic component of a toxin-antitoxin (TA) module
SYN7502_RS02215	COG1940	carbohydrate kinase activity
SYN7502_RS02230	COG1366	Belongs to the anti-sigma-factor antagonist family
SYN7502_RS02235	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SYN7502_RS02240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYN7502_RS02250	COG0363	glucosamine-6-phosphate deaminase activity
SYN7502_RS02260	COG0436	Aminotransferase
SYN7502_RS02290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYN7502_RS02345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SYN7502_RS02350	COG0800	Aldolase
SYN7502_RS02355	COG0484	heat shock protein binding
SYN7502_RS02360	COG3781	membrane
SYN7502_RS02370	COG1333	cytochrome c biogenesis protein
SYN7502_RS02375	COG2201	protein-glutamate methylesterase activity
SYN7502_RS02380	COG1716	ATPase activity
SYN7502_RS02385	COG2304	oxidoreductase activity
SYN7502_RS02395	COG0076	glutamate decarboxylase activity
SYN7502_RS02400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYN7502_RS02405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SYN7502_RS02420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SYN7502_RS02425	COG3118	belongs to the thioredoxin family
SYN7502_RS02440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYN7502_RS02445	COG1615	UPF0182 protein
SYN7502_RS02460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SYN7502_RS02465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SYN7502_RS02475	COG1007	ATP synthesis coupled electron transport
SYN7502_RS02480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SYN7502_RS02490	COG1797	cobyrinic acid a,c-diamide synthase activity
SYN7502_RS02495	COG0523	cobalamin synthesis protein
SYN7502_RS02540	COG0110	maltose O-acetyltransferase activity
SYN7502_RS02545	COG2226	methyltransferase
SYN7502_RS02560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SYN7502_RS02565	COG5002	protein histidine kinase activity
SYN7502_RS02570	COG0436	Aminotransferase
SYN7502_RS02575	COG0534	Mate efflux family protein
SYN7502_RS02580	COG0440	acetolactate synthase activity
SYN7502_RS02585	COG3706	GGDEF domain
SYN7502_RS02590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SYN7502_RS02600	COG3956	TIGRFAM MazG family protein
SYN7502_RS02605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SYN7502_RS02615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SYN7502_RS02625	COG0321	lipoyl(octanoyl) transferase activity
SYN7502_RS02690	COG0395	ABC-type sugar transport system, permease component
SYN7502_RS02695	COG1217	gtp-binding protein TYPA
SYN7502_RS02700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYN7502_RS02715	COG0625	glutathione transferase activity
SYN7502_RS02730	COG0644	oxidoreductase
SYN7502_RS02735	COG0137	argininosuccinate synthase activity
SYN7502_RS02765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SYN7502_RS02775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYN7502_RS02820	COG1126	abc transporter atp-binding protein
SYN7502_RS02850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS02885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SYN7502_RS02900	COG0575	Belongs to the CDS family
SYN7502_RS02905	COG0484	heat shock protein binding
SYN7502_RS02910	COG0704	Plays a role in the regulation of phosphate uptake
SYN7502_RS02935	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SYN7502_RS02935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYN7502_RS02940	COG0589	response to stress
SYN7502_RS02945	COG0488	(ABC) transporter
SYN7502_RS02975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SYN7502_RS02985	COG0750	zinc metalloprotease
SYN7502_RS02990	COG4636	protein conserved in cyanobacteria
SYN7502_RS02995	COG2217	Heavy metal translocating P-type atpase
SYN7502_RS03000	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS03005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS03010	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SYN7502_RS03015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SYN7502_RS03015	COG4451	ribulose bisphosphate carboxylase, small
SYN7502_RS03020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SYN7502_RS03025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SYN7502_RS03030	COG1459	type II secretion system
SYN7502_RS03040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SYN7502_RS03045	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SYN7502_RS03050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SYN7502_RS03055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SYN7502_RS03070	COG0629	single-stranded DNA binding
SYN7502_RS03090	COG2197	response regulator
SYN7502_RS03095	COG0475	glutathione-regulated potassium exporter activity
SYN7502_RS03105	COG0067	glutamate synthase
SYN7502_RS03105	COG0069	glutamate synthase activity
SYN7502_RS03105	COG0070	glutamate synthase
SYN7502_RS03110	COG1309	transcriptional regulator
SYN7502_RS03125	COG0454	-acetyltransferase
SYN7502_RS03145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SYN7502_RS03165	COG2226	methyltransferase
SYN7502_RS03170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYN7502_RS03205	COG1002	Type II restriction enzyme, methylase subunits
SYN7502_RS03210	COG0196	riboflavin kinase activity
SYN7502_RS03220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SYN7502_RS03240	COG2091	lysine biosynthetic process via aminoadipic acid
SYN7502_RS03245	COG0343	queuine tRNA-ribosyltransferase activity
SYN7502_RS03255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SYN7502_RS03275	COG0701	Predicted permease
SYN7502_RS03305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYN7502_RS03305	COG0426	domain, Protein
SYN7502_RS03320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SYN7502_RS03325	COG0811	peptide transport
SYN7502_RS03330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SYN7502_RS03405	COG1012	belongs to the aldehyde dehydrogenase family
SYN7502_RS03410	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYN7502_RS03410	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYN7502_RS03440	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS03440	COG0515	serine threonine protein kinase
SYN7502_RS03445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SYN7502_RS03475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SYN7502_RS03480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SYN7502_RS03485	COG0540	Belongs to the ATCase OTCase family
SYN7502_RS03510	COG1070	Carbohydrate kinase
SYN7502_RS03535	COG0181	hydroxymethylbilane synthase activity
SYN7502_RS03550	COG0439	Biotin carboxylase
SYN7502_RS03570	COG3665	Urea carboxylase-associated protein
SYN7502_RS03575	COG3665	Urea carboxylase-associated protein
SYN7502_RS03585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYN7502_RS03590	COG1116	anion transmembrane transporter activity
SYN7502_RS03600	COG0415	Belongs to the DNA photolyase family
SYN7502_RS03640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYN7502_RS03645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYN7502_RS03660	COG0300	oxidoreductase activity
SYN7502_RS03660	COG3000	fatty acid hydroxylase
SYN7502_RS03680	COG1331	Highly conserved protein containing a thioredoxin domain
SYN7502_RS03700	COG0832	Belongs to the urease beta subunit family
SYN7502_RS03705	COG0778	Nitroreductase
SYN7502_RS03710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYN7502_RS03720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYN7502_RS03725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SYN7502_RS03745	COG3842	ATPase activity
SYN7502_RS03750	COG1587	Uroporphyrinogen-III synthase
SYN7502_RS03760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SYN7502_RS03770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SYN7502_RS03775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SYN7502_RS03780	COG0088	Forms part of the polypeptide exit tunnel
SYN7502_RS03785	COG0089	rRNA binding
SYN7502_RS03790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SYN7502_RS03795	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SYN7502_RS03800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SYN7502_RS03805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SYN7502_RS03810	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SYN7502_RS03815	COG0255	Belongs to the universal ribosomal protein uL29 family
SYN7502_RS03820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SYN7502_RS03825	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SYN7502_RS03830	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SYN7502_RS03835	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SYN7502_RS03840	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SYN7502_RS03845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SYN7502_RS03850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SYN7502_RS03855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SYN7502_RS03860	COG0200	Binds to the 23S rRNA
SYN7502_RS03865	COG0201	protein transport
SYN7502_RS03870	COG0563	adenylate kinase activity
SYN7502_RS03875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SYN7502_RS03890	COG4783	chaperone-mediated protein folding
SYN7502_RS03905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SYN7502_RS03910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SYN7502_RS03960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SYN7502_RS03970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SYN7502_RS03985	COG0628	permease
SYN7502_RS04000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYN7502_RS04010	COG1543	Belongs to the glycosyl hydrolase 57 family
SYN7502_RS04065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYN7502_RS04140	COG0582	viral genome integration into host DNA
SYN7502_RS04155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYN7502_RS04165	COG1136	(ABC) transporter
SYN7502_RS04165	COG0577	efflux transmembrane transporter activity
SYN7502_RS04175	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SYN7502_RS04195	COG0457	Tetratricopeptide repeat
SYN7502_RS04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYN7502_RS04230	COG1136	(ABC) transporter
SYN7502_RS04230	COG0577	efflux transmembrane transporter activity
SYN7502_RS04235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SYN7502_RS04255	COG1252	NADH dehydrogenase
SYN7502_RS04260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYN7502_RS04275	COG1175	transmembrane transport
SYN7502_RS04285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYN7502_RS04295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SYN7502_RS04300	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SYN7502_RS04350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYN7502_RS04375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SYN7502_RS04410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYN7502_RS04415	COG1045	serine acetyltransferase
SYN7502_RS04440	COG0189	ligase activity
SYN7502_RS04450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SYN7502_RS04495	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SYN7502_RS04505	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SYN7502_RS04520	COG0268	Binds directly to 16S ribosomal RNA
SYN7502_RS04530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SYN7502_RS04540	COG0109	protoheme IX farnesyltransferase activity
SYN7502_RS04545	COG0058	SHG alpha-glucan phosphorylase activity
SYN7502_RS04550	COG0717	Belongs to the dCTP deaminase family
SYN7502_RS04570	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS04590	COG4968	Prepilin-type N-terminal cleavage methylation domain
SYN7502_RS04615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SYN7502_RS04625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SYN7502_RS04635	COG1446	asparaginase
SYN7502_RS04650	COG1169	isochorismate synthase
SYN7502_RS04660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SYN7502_RS04665	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SYN7502_RS04680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SYN7502_RS04685	COG1192	Involved in chromosome partitioning
SYN7502_RS04695	COG1666	GTP binding
SYN7502_RS04700	COG0784	Response regulator, receiver
SYN7502_RS04745	COG0740	serine-type endopeptidase activity
SYN7502_RS04750	COG0740	serine-type endopeptidase activity
SYN7502_RS04780	COG4581	dead DEAH box helicase
SYN7502_RS04790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SYN7502_RS04795	COG3459	Glycosyltransferase 36 associated
SYN7502_RS04800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SYN7502_RS04825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SYN7502_RS04835	COG0643	Histidine kinase
SYN7502_RS04835	COG2198	Histidine kinase
SYN7502_RS04835	COG0784	Response regulator, receiver
SYN7502_RS04875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SYN7502_RS04880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SYN7502_RS04885	COG3429	Glucose-6-phosphate dehydrogenase subunit
SYN7502_RS04885	COG3409	Peptidoglycan-binding domain 1 protein
SYN7502_RS04890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SYN7502_RS04905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SYN7502_RS04925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SYN7502_RS04925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SYN7502_RS04960	COG1196	nuclear chromosome segregation
SYN7502_RS04965	COG0450	alkyl hydroperoxide reductase
SYN7502_RS04970	COG0131	Imidazoleglycerol-phosphate dehydratase
SYN7502_RS04975	COG2264	protein methyltransferase activity
SYN7502_RS04985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SYN7502_RS04990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SYN7502_RS04995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SYN7502_RS05015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SYN7502_RS05020	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SYN7502_RS05030	COG2177	Part of the ABC transporter FtsEX involved in
SYN7502_RS05035	COG0521	Mo-molybdopterin cofactor biosynthetic process
SYN7502_RS05045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SYN7502_RS05055	COG1773	rubredoxin
SYN7502_RS05060	COG4447	cellulose binding
SYN7502_RS05065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SYN7502_RS05070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SYN7502_RS05075	COG0511	ligase activity, forming carbon-carbon bonds
SYN7502_RS05085	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYN7502_RS05090	COG1234	tRNA 3'-trailer cleavage
SYN7502_RS05095	COG0285	dihydrofolate synthase activity
SYN7502_RS05105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SYN7502_RS05125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SYN7502_RS05160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYN7502_RS05160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYN7502_RS05170	COG0443	Heat shock 70 kDa protein
SYN7502_RS05175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SYN7502_RS05230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SYN7502_RS05255	COG0277	FAD linked oxidase domain protein
SYN7502_RS05260	COG2045	Belongs to the ComB family
SYN7502_RS05275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SYN7502_RS05280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SYN7502_RS05325	COG3437	response regulator, receiver
SYN7502_RS05325	COG3850	Histidine kinase
SYN7502_RS05325	COG2205	protein histidine kinase activity
SYN7502_RS05325	COG4999	Histidine kinase
SYN7502_RS05330	COG2205	protein histidine kinase activity
SYN7502_RS05335	COG0459	protein refolding
SYN7502_RS05340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SYN7502_RS05360	COG0592	DNA-directed DNA polymerase activity
SYN7502_RS05370	COG2205	protein histidine kinase activity
SYN7502_RS05375	COG2205	protein histidine kinase activity
SYN7502_RS05385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SYN7502_RS05385	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SYN7502_RS05390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SYN7502_RS05390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SYN7502_RS05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYN7502_RS05400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SYN7502_RS05410	COG4251	negative regulation of phosphorylation
SYN7502_RS05415	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYN7502_RS05435	COG0668	transmembrane transport
SYN7502_RS05440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SYN7502_RS05445	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SYN7502_RS05465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SYN7502_RS05470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYN7502_RS05480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SYN7502_RS05490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYN7502_RS05515	COG0435	Glutathione S-transferase
SYN7502_RS05520	COG3384	dioxygenase
SYN7502_RS05550	COG1716	ATPase activity
SYN7502_RS05550	COG0842	Transport permease protein
SYN7502_RS05550	COG1131	(ABC) transporter
SYN7502_RS05565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS05585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SYN7502_RS05590	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SYN7502_RS05600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SYN7502_RS05620	COG0768	penicillin binding
SYN7502_RS05630	COG2226	methyltransferase
SYN7502_RS05635	COG0124	histidyl-tRNA synthetase
SYN7502_RS05645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYN7502_RS05650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYN7502_RS05655	COG3852	Histidine kinase
SYN7502_RS05660	COG1606	tRNA processing
SYN7502_RS05670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SYN7502_RS05760	COG0515	serine threonine protein kinase
SYN7502_RS05765	COG0586	Pfam SNARE associated Golgi protein
SYN7502_RS05775	COG1802	Transcriptional regulator
SYN7502_RS05790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SYN7502_RS05825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SYN7502_RS05835	COG0148	phosphopyruvate hydratase activity
SYN7502_RS05840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYN7502_RS05865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SYN7502_RS05875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SYN7502_RS05910	COG0784	Response regulator, receiver
SYN7502_RS05910	COG2205	protein histidine kinase activity
SYN7502_RS05920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYN7502_RS05925	COG4251	negative regulation of phosphorylation
SYN7502_RS05930	COG0784	Response regulator, receiver
SYN7502_RS05930	COG2205	protein histidine kinase activity
SYN7502_RS05950	COG0481	GTPase activity
SYN7502_RS05955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYN7502_RS05955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYN7502_RS05990	COG0251	oxidation-reduction process
SYN7502_RS06020	COG0424	maF-like protein
SYN7502_RS06025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYN7502_RS06035	COG0505	Belongs to the CarA family
SYN7502_RS06040	COG0450	alkyl hydroperoxide reductase
SYN7502_RS06080	COG1104	cysteine desulfurase activity
SYN7502_RS06105	COG0582	viral genome integration into host DNA
SYN7502_RS06110	COG0598	Magnesium transport protein CorA
SYN7502_RS06120	COG1316	TRANSCRIPTIONal
SYN7502_RS06130	COG0316	Belongs to the HesB IscA family
SYN7502_RS06140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYN7502_RS06145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SYN7502_RS06160	COG0322	excinuclease ABC activity
SYN7502_RS06165	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS06170	COG2255	four-way junction helicase activity
SYN7502_RS06190	COG1045	serine acetyltransferase
SYN7502_RS06215	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SYN7502_RS06220	COG0439	Biotin carboxylase
SYN7502_RS06235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS06240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS06255	COG1253	flavin adenine dinucleotide binding
SYN7502_RS06260	COG0047	phosphoribosylformylglycinamidine synthase activity
SYN7502_RS06290	COG2154	pterin-4-alpha-carbinolamine dehydratase
SYN7502_RS06295	COG0445	tRNA wobble uridine modification
SYN7502_RS06300	COG1970	mechanosensitive ion channel activity
SYN7502_RS06305	COG0483	inositol monophosphate 1-phosphatase activity
SYN7502_RS06320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SYN7502_RS06325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SYN7502_RS06330	COG0765	amino acid transport
SYN7502_RS06340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN7502_RS06355	COG1253	flavin adenine dinucleotide binding
SYN7502_RS06360	COG1132	(ABC) transporter
SYN7502_RS06375	COG0571	ribonuclease III activity
SYN7502_RS06380	COG0004	ammonium transporteR
SYN7502_RS06395	COG1845	cytochrome c oxidase, subunit III
SYN7502_RS06400	COG4942	peptidase
SYN7502_RS06410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SYN7502_RS06415	COG2894	cell division
SYN7502_RS06420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SYN7502_RS06425	COG0352	thiamine-phosphate diphosphorylase activity
SYN7502_RS06430	COG3437	response regulator, receiver
SYN7502_RS06440	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS06455	COG2319	Wd-40 repeat
SYN7502_RS06455	COG3903	Transcriptional regulator
SYN7502_RS06460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYN7502_RS06470	COG0133	tryptophan synthase activity
SYN7502_RS06485	COG1012	belongs to the aldehyde dehydrogenase family
SYN7502_RS06490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SYN7502_RS06500	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYN7502_RS06505	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
SYN7502_RS06515	COG0537	adenosine 5'-monophosphoramidase activity
SYN7502_RS06535	COG0625	glutathione transferase activity
SYN7502_RS06540	COG0489	protein tyrosine kinase activity
SYN7502_RS06545	COG0484	heat shock protein binding
SYN7502_RS06550	COG0724	RNA recognition motif
SYN7502_RS06560	COG0632	four-way junction helicase activity
SYN7502_RS06570	COG0515	serine threonine protein kinase
SYN7502_RS06570	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS06575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYN7502_RS06580	COG4401	Chorismate mutase type I
SYN7502_RS06625	COG1619	proteins homologs of microcin C7 resistance protein MccF
SYN7502_RS06630	COG0436	Aminotransferase
SYN7502_RS06635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SYN7502_RS06640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYN7502_RS06645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SYN7502_RS06650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SYN7502_RS06720	COG1160	GTP binding
SYN7502_RS06725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYN7502_RS06740	COG0824	Thioesterase
SYN7502_RS06750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SYN7502_RS06770	COG0772	Belongs to the SEDS family
SYN7502_RS06780	COG0336	Belongs to the RNA methyltransferase TrmD family
SYN7502_RS06785	COG3937	granule-associated protein
SYN7502_RS06795	COG0702	epimerase
SYN7502_RS06800	COG0539	negative regulation of cytoplasmic translation
SYN7502_RS06825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SYN7502_RS06840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SYN7502_RS06880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SYN7502_RS06900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SYN7502_RS06915	COG1122	ATPase activity
SYN7502_RS06935	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS06940	COG2081	HI0933 family
SYN7502_RS06945	COG5002	protein histidine kinase activity
SYN7502_RS06945	COG0784	Response regulator, receiver
SYN7502_RS06950	COG2205	protein histidine kinase activity
SYN7502_RS06965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYN7502_RS06975	COG2385	sporulation resulting in formation of a cellular spore
SYN7502_RS06980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SYN7502_RS06985	COG0724	RNA recognition motif
SYN7502_RS06990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SYN7502_RS06990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYN7502_RS06995	COG0714	Associated with various cellular activities
SYN7502_RS07025	COG1027	Aspartate ammonia-lyase
SYN7502_RS07075	COG2002	toxin-antitoxin pair type II binding
SYN7502_RS07090	COG2211	Major facilitator Superfamily
SYN7502_RS07100	COG2211	Major facilitator Superfamily
SYN7502_RS07125	COG2197	response regulator
SYN7502_RS07135	COG2319	Wd-40 repeat
SYN7502_RS07135	COG3903	Transcriptional regulator
SYN7502_RS07160	COG2211	Major facilitator Superfamily
SYN7502_RS07370	COG1396	sequence-specific DNA binding
SYN7502_RS07415	COG5002	protein histidine kinase activity
SYN7502_RS07455	COG2217	Heavy metal translocating P-type atpase
SYN7502_RS07470	COG1230	cation diffusion facilitator family transporter
SYN7502_RS07505	COG2932	Transcriptional regulator
SYN7502_RS07550	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SYN7502_RS07555	COG0072	phenylalanine-tRNA ligase activity
SYN7502_RS07555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SYN7502_RS07560	COG0179	Fumarylacetoacetate (FAA) hydrolase
SYN7502_RS07565	COG0335	large ribosomal subunit rRNA binding
SYN7502_RS07575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SYN7502_RS07580	COG0250	Participates in transcription elongation, termination and antitermination
SYN7502_RS07585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SYN7502_RS07590	COG0081	regulation of translation
SYN7502_RS07595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SYN7502_RS07600	COG0222	ribosome binding
SYN7502_RS07605	COG0140	phosphoribosyl-ATP diphosphatase activity
SYN7502_RS07605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SYN7502_RS07610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SYN7502_RS07615	COG0668	transmembrane transport
SYN7502_RS07625	COG2197	response regulator
SYN7502_RS07630	COG1640	4-alpha-glucanotransferase
SYN7502_RS07635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SYN7502_RS07650	COG2208	phosphoserine phosphatase activity
SYN7502_RS07655	COG0552	protein localization to endoplasmic reticulum
SYN7502_RS07660	COG0783	Belongs to the Dps family
SYN7502_RS07665	COG0516	GMP reductase activity
SYN7502_RS07675	COG3659	wide pore channel activity
SYN7502_RS07680	COG3903	Transcriptional regulator
SYN7502_RS07680	COG2319	Wd-40 repeat
SYN7502_RS07685	COG0586	Pfam SNARE associated Golgi protein
SYN7502_RS07755	COG0393	Putative heavy-metal-binding
SYN7502_RS07770	COG3228	Belongs to the MtfA family
SYN7502_RS07795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYN7502_RS07805	COG0726	polysaccharide deacetylase
SYN7502_RS07805	COG1649	PFAM Uncharacterised BCR, COG1649
SYN7502_RS07810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SYN7502_RS07815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SYN7502_RS07820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SYN7502_RS07825	COG1691	(AIR) carboxylase
SYN7502_RS07840	COG1994	Peptidase M50
SYN7502_RS07840	COG0517	IMP dehydrogenase activity
SYN7502_RS07845	COG0572	uridine kinase
SYN7502_RS07865	COG2385	sporulation resulting in formation of a cellular spore
SYN7502_RS07870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYN7502_RS07870	COG0426	domain, Protein
SYN7502_RS07875	COG2076	Multidrug Resistance protein
SYN7502_RS07885	COG2345	Transcriptional regulator
SYN7502_RS07910	COG0494	nUDIX hydrolase
SYN7502_RS07915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SYN7502_RS07965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS07980	COG1178	ABC-type Fe3 transport system permease component
SYN7502_RS07985	COG3842	ATPase activity
SYN7502_RS07995	COG1840	ABC-type Fe3 transport system, periplasmic component
SYN7502_RS08000	COG3118	belongs to the thioredoxin family
SYN7502_RS08005	COG1902	pentaerythritol trinitrate reductase activity
SYN7502_RS08015	COG1032	radical SAM domain protein
SYN7502_RS08020	COG0583	DNA-binding transcription factor activity
SYN7502_RS08030	COG0351	phosphomethylpyrimidine kinase
SYN7502_RS08040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SYN7502_RS08045	COG0649	NAD binding
SYN7502_RS08060	COG1716	ATPase activity
SYN7502_RS08060	COG5001	Diguanylate cyclase
SYN7502_RS08070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SYN7502_RS08095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYN7502_RS08105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SYN7502_RS08110	COG0793	Belongs to the peptidase S41A family
SYN7502_RS08130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SYN7502_RS08135	COG0432	Pfam Uncharacterised protein family UPF0047
SYN7502_RS08140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SYN7502_RS08150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SYN7502_RS08165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYN7502_RS08170	COG0730	response to heat
SYN7502_RS08180	COG4451	ribulose bisphosphate carboxylase, small
SYN7502_RS08190	COG1850	ribulose-bisphosphate carboxylase activity
SYN7502_RS08200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYN7502_RS08215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SYN7502_RS08225	COG2319	Wd-40 repeat
SYN7502_RS08230	COG2319	Wd-40 repeat
SYN7502_RS08250	COG1082	Xylose isomerase domain protein TIM barrel
SYN7502_RS08270	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SYN7502_RS08275	COG2770	Histidine kinase
SYN7502_RS08275	COG2208	phosphoserine phosphatase activity
SYN7502_RS08290	COG0003	Pfam Anion-transporting ATPase
SYN7502_RS08295	COG5002	protein histidine kinase activity
SYN7502_RS08310	COG0583	DNA-binding transcription factor activity
SYN7502_RS08315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYN7502_RS08335	COG0233	cytoplasmic translational termination
SYN7502_RS08340	COG0528	UMP kinase activity
SYN7502_RS08350	COG0515	serine threonine protein kinase
SYN7502_RS08350	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS08355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SYN7502_RS08360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SYN7502_RS08365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SYN7502_RS08380	COG0330	HflC and HflK could
SYN7502_RS08385	COG0587	DNA-directed DNA polymerase activity
SYN7502_RS08390	COG0159	tryptophan synthase activity
SYN7502_RS08395	COG4221	oxidoreductase activity
SYN7502_RS08400	COG2166	iron-sulfur cluster assembly
SYN7502_RS08415	COG0659	secondary active sulfate transmembrane transporter activity
SYN7502_RS08435	COG0590	tRNA wobble adenosine to inosine editing
SYN7502_RS08440	COG1575	Belongs to the MenA family. Type 1 subfamily
SYN7502_RS08515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYN7502_RS08520	COG0631	protein serine/threonine phosphatase activity
SYN7502_RS08525	COG1496	oxidoreductase activity
SYN7502_RS08545	COG1136	(ABC) transporter
SYN7502_RS08590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SYN7502_RS08605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS08615	COG1116	anion transmembrane transporter activity
SYN7502_RS08615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SYN7502_RS08620	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SYN7502_RS08625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SYN7502_RS08640	COG2203	Gaf domain
SYN7502_RS08640	COG3706	GGDEF domain
SYN7502_RS08640	COG5001	Diguanylate cyclase
SYN7502_RS08640	COG4251	negative regulation of phosphorylation
SYN7502_RS08655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SYN7502_RS08700	COG0848	biopolymer transport protein
SYN7502_RS08730	COG3845	ABC transporter
SYN7502_RS08735	COG1335	isochorismatase
SYN7502_RS08740	COG1079	Belongs to the binding-protein-dependent transport system permease family
SYN7502_RS08745	COG4603	Belongs to the binding-protein-dependent transport system permease family
SYN7502_RS08755	COG3659	wide pore channel activity
SYN7502_RS08760	COG2252	PERMEase
SYN7502_RS08770	COG3224	Antibiotic biosynthesis monooxygenase
SYN7502_RS08780	COG0633	Ferredoxin
SYN7502_RS08860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SYN7502_RS08860	COG3266	domain, Protein
SYN7502_RS08865	COG0138	bifunctional purine biosynthesis protein purh
SYN7502_RS08880	COG0443	Heat shock 70 kDa protein
SYN7502_RS08885	COG1191	sigma factor activity
SYN7502_RS08895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SYN7502_RS08900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SYN7502_RS08905	COG0101	tRNA pseudouridine synthase activity
SYN7502_RS08910	COG0203	ribosomal protein L17
SYN7502_RS08915	COG0202	RNA polymerase activity
SYN7502_RS08920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SYN7502_RS08925	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SYN7502_RS08950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYN7502_RS08950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYN7502_RS08965	COG0542	response to heat
SYN7502_RS08975	COG0398	Pfam SNARE associated Golgi protein
SYN7502_RS08985	COG1429	ligase activity, forming nitrogen-metal bonds
SYN7502_RS08990	COG0784	Response regulator, receiver
SYN7502_RS08990	COG0784	Response regulator, receiver
SYN7502_RS08990	COG0643	Histidine kinase
SYN7502_RS08990	COG2198	Histidine kinase
SYN7502_RS08990	COG0643	Histidine kinase
SYN7502_RS08990	COG2198	Histidine kinase
SYN7502_RS08995	COG0840	transmembrane signaling receptor activity
SYN7502_RS09020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SYN7502_RS09030	COG0009	L-threonylcarbamoyladenylate synthase
SYN7502_RS09070	COG0156	8-amino-7-oxononanoate synthase activity
SYN7502_RS09080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SYN7502_RS09085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SYN7502_RS09090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SYN7502_RS09100	COG2814	Major facilitator Superfamily
SYN7502_RS09135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYN7502_RS09150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SYN7502_RS09155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SYN7502_RS09170	COG0412	Dienelactone hydrolase
SYN7502_RS09180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SYN7502_RS09195	COG2022	thiamine diphosphate biosynthetic process
SYN7502_RS09200	COG1959	2 iron, 2 sulfur cluster binding
SYN7502_RS09205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SYN7502_RS09215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SYN7502_RS09225	COG0237	dephospho-CoA kinase activity
SYN7502_RS09230	COG1192	Involved in chromosome partitioning
SYN7502_RS09250	COG3335	DDE superfamily endonuclease
SYN7502_RS09260	COG0339	signal peptide processing
SYN7502_RS09275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SYN7502_RS09285	COG1702	phosphate starvation-inducible protein PhoH
SYN7502_RS09305	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SYN7502_RS09310	COG0589	response to stress
SYN7502_RS09320	COG0180	Tryptophanyl-tRNA synthetase
SYN7502_RS09325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYN7502_RS09340	COG0038	chloride channel
SYN7502_RS09345	COG0557	exoribonuclease II activity
SYN7502_RS09385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYN7502_RS09390	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS09400	COG0640	Transcriptional regulator
SYN7502_RS09415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SYN7502_RS09420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SYN7502_RS09425	COG0019	diaminopimelate decarboxylase activity
SYN7502_RS09435	COG0612	Peptidase, M16
SYN7502_RS09440	COG2208	phosphoserine phosphatase activity
SYN7502_RS09450	COG2154	pterin-4-alpha-carbinolamine dehydratase
SYN7502_RS09495	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SYN7502_RS09500	COG0025	NhaP-type Na H and K H
SYN7502_RS09530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SYN7502_RS09555	COG0228	four-way junction DNA binding
SYN7502_RS09560	COG1837	Belongs to the UPF0109 family
SYN7502_RS09565	COG1058	Belongs to the CinA family
SYN7502_RS09565	COG1546	Belongs to the CinA family
SYN7502_RS09575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SYN7502_RS09580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SYN7502_RS09585	COG0083	homoserine kinase activity
SYN7502_RS09595	COG0735	belongs to the Fur family
SYN7502_RS09600	COG0174	glutamine synthetase
SYN7502_RS09615	COG0475	glutathione-regulated potassium exporter activity
SYN7502_RS09620	COG0469	pyruvate kinase activity
SYN7502_RS09640	COG2119	membrane
SYN7502_RS09665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYN7502_RS09670	COG1741	Belongs to the pirin family
SYN7502_RS09675	COG0463	Glycosyl transferase, family 2
SYN7502_RS09685	COG1899	peptidyl-lysine modification to peptidyl-hypusine
SYN7502_RS09695	COG0772	Belongs to the SEDS family
SYN7502_RS09700	COG0492	ferredoxin-NADP+ reductase activity
SYN7502_RS09710	COG0613	PHP domain protein
SYN7502_RS09715	COG4149	molybdate abc transporter
SYN7502_RS09725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYN7502_RS09730	COG0312	modulator of DNA gyrase
SYN7502_RS09735	COG0359	binds to the 23S rRNA
SYN7502_RS09770	COG3046	protein related to deoxyribodipyrimidine photolyase
SYN7502_RS09775	COG0123	including yeast histone deacetylase and acetoin utilization protein
SYN7502_RS09795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYN7502_RS09820	COG1410	methionine synthase
SYN7502_RS09820	COG0646	methionine synthase
SYN7502_RS09835	COG1595	DNA-templated transcription, initiation
SYN7502_RS09860	COG3631	Ketosteroid isomerase-related protein
SYN7502_RS09870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYN7502_RS09910	COG1049	propionate catabolic process, 2-methylcitrate cycle
SYN7502_RS09915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SYN7502_RS09925	COG3063	Type IV pilus biogenesis stability protein PilW
SYN7502_RS09945	COG0456	acetyltransferase
SYN7502_RS09950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SYN7502_RS09960	COG1252	NADH dehydrogenase
SYN7502_RS09965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYN7502_RS09970	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SYN7502_RS09975	COG1166	arginine decarboxylase activity
SYN7502_RS09980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYN7502_RS09990	COG2223	nitrite transmembrane transporter activity
SYN7502_RS10000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS10010	COG0163	prenyltransferase activity
SYN7502_RS10015	COG0113	porphobilinogen synthase activity
SYN7502_RS10025	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS10030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SYN7502_RS10070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SYN7502_RS10170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SYN7502_RS10180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SYN7502_RS10215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SYN7502_RS10220	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SYN7502_RS10245	COG0271	Belongs to the BolA IbaG family
SYN7502_RS10255	COG0170	dolichyl monophosphate biosynthetic process
SYN7502_RS10265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SYN7502_RS10275	COG5002	protein histidine kinase activity
SYN7502_RS10295	COG0728	peptidoglycan biosynthetic process
SYN7502_RS10305	COG0752	glycyl-tRNA synthetase alpha subunit
SYN7502_RS10335	COG0672	)-iron permease
SYN7502_RS10350	COG1247	-acetyltransferase
SYN7502_RS10355	COG0017	Asparaginyl-tRNA synthetase
SYN7502_RS10420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SYN7502_RS10445	COG0187	DNA topoisomerase II activity
SYN7502_RS10445	COG1372	Participates in initiation and elongation during chromosome replication
SYN7502_RS10455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SYN7502_RS10455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SYN7502_RS10480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SYN7502_RS10485	COG1836	PFAM Integral membrane protein DUF92
SYN7502_RS10520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SYN7502_RS10520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SYN7502_RS10530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SYN7502_RS10540	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SYN7502_RS10555	COG1846	Transcriptional regulator
SYN7502_RS10565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SYN7502_RS10575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SYN7502_RS10590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SYN7502_RS10595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYN7502_RS10595	COG0512	Glutamine amidotransferase of anthranilate synthase
SYN7502_RS10605	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS10615	COG1472	Belongs to the glycosyl hydrolase 3 family
SYN7502_RS10620	COG4251	negative regulation of phosphorylation
SYN7502_RS10625	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS10630	COG0835	chemotaxis
SYN7502_RS10635	COG3290	protein histidine kinase activity
SYN7502_RS10635	COG0840	transmembrane signaling receptor activity
SYN7502_RS10645	COG2201	protein-glutamate methylesterase activity
SYN7502_RS10655	COG2201	protein-glutamate methylesterase activity
SYN7502_RS10680	COG2226	methyltransferase
SYN7502_RS10745	COG0523	cobalamin synthesis protein
SYN7502_RS10750	COG0714	Associated with various cellular activities
SYN7502_RS10765	COG2205	protein histidine kinase activity
SYN7502_RS10765	COG0784	Response regulator, receiver
SYN7502_RS10775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS10795	COG2010	Cytochrome c
SYN7502_RS10800	COG3794	PFAM blue (type 1) copper domain protein
SYN7502_RS10805	COG1126	abc transporter atp-binding protein
SYN7502_RS10810	COG0765	amino acid transport
SYN7502_RS10815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYN7502_RS10820	COG3659	wide pore channel activity
SYN7502_RS10830	COG0066	3-isopropylmalate dehydratase activity
SYN7502_RS10835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYN7502_RS10845	COG0194	GDP metabolic process
SYN7502_RS10850	COG2052	Domain of unknown function (DUF370)
SYN7502_RS10865	COG3536	Protein conserved in bacteria
SYN7502_RS10885	COG0825	malonyl-CoA metabolic process
SYN7502_RS10905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYN7502_RS10910	COG1012	belongs to the aldehyde dehydrogenase family
SYN7502_RS10925	COG0515	serine threonine protein kinase
SYN7502_RS10930	COG0519	Catalyzes the synthesis of GMP from XMP
SYN7502_RS10930	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SYN7502_RS10940	COG1121	(ABC) transporter
SYN7502_RS10955	COG0360	Binds together with S18 to 16S ribosomal RNA
SYN7502_RS10960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SYN7502_RS10990	COG0165	Argininosuccinate lyase
SYN7502_RS11000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYN7502_RS11005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SYN7502_RS11010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SYN7502_RS11015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SYN7502_RS11020	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SYN7502_RS11035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYN7502_RS11050	COG1562	ergosterol biosynthetic process
SYN7502_RS11055	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYN7502_RS11055	COG0493	'glutamate synthase
SYN7502_RS11060	COG4372	Transposase
SYN7502_RS11065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SYN7502_RS11075	COG3266	domain, Protein
SYN7502_RS11075	COG0515	serine threonine protein kinase
SYN7502_RS11080	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SYN7502_RS11090	COG2885	chlorophyll binding
SYN7502_RS11095	COG2885	chlorophyll binding
SYN7502_RS11105	COG0154	amidase activity
SYN7502_RS11110	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS11115	COG1216	Glycosyl transferase, family 2
SYN7502_RS11120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SYN7502_RS11125	COG1078	dGTPase activity
SYN7502_RS11140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SYN7502_RS11155	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SYN7502_RS11180	COG5346	Predicted membrane protein (DUF2335)
SYN7502_RS11230	COG1192	Involved in chromosome partitioning
SYN7502_RS11275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYN7502_RS11285	COG0667	Aldo Keto reductase
SYN7502_RS11305	COG0494	nUDIX hydrolase
SYN7502_RS11345	COG1196	nuclear chromosome segregation
SYN7502_RS11380	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYN7502_RS11385	COG0038	chloride channel
SYN7502_RS11390	COG0457	Tetratricopeptide repeat
SYN7502_RS11390	COG0463	Glycosyl transferase, family 2
SYN7502_RS11395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SYN7502_RS11400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SYN7502_RS11405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYN7502_RS11415	COG3854	ATPases associated with a variety of cellular activities
SYN7502_RS11420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SYN7502_RS11430	COG0515	serine threonine protein kinase
SYN7502_RS11435	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS11435	COG0515	serine threonine protein kinase
SYN7502_RS11445	COG0779	Required for maturation of 30S ribosomal subunits
SYN7502_RS11450	COG0195	Participates in both transcription termination and antitermination
SYN7502_RS11480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SYN7502_RS11505	COG3237	CsbD-like
SYN7502_RS11525	COG0443	Heat shock 70 kDa protein
SYN7502_RS11535	COG0275	rRNA processing
SYN7502_RS11540	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SYN7502_RS11545	COG4243	Vitamin k epoxide reductase
SYN7502_RS11610	COG0358	DNA primase activity
SYN7502_RS11625	COG0134	indole-3-glycerol-phosphate synthase activity
SYN7502_RS11635	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SYN7502_RS11650	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SYN7502_RS11655	COG1381	Involved in DNA repair and RecF pathway recombination
SYN7502_RS11665	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS11670	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS11685	COG0740	serine-type endopeptidase activity
SYN7502_RS11690	COG1473	amidohydrolase
SYN7502_RS11695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SYN7502_RS11695	COG0617	tRNA 3'-terminal CCA addition
SYN7502_RS11695	COG0517	IMP dehydrogenase activity
SYN7502_RS11700	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYN7502_RS11710	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYN7502_RS11725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SYN7502_RS11735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SYN7502_RS11745	COG0805	protein transport
SYN7502_RS11780	COG0706	membrane insertase activity
SYN7502_RS11815	COG0107	imidazoleglycerol-phosphate synthase activity
SYN7502_RS11830	COG3264	Mechanosensitive ion channel
SYN7502_RS11830	COG1511	domain protein
SYN7502_RS11835	COG0315	cyclic pyranopterin monophosphate synthase activity
SYN7502_RS11840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYN7502_RS11855	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SYN7502_RS11865	COG0402	S-adenosylhomocysteine deaminase activity
SYN7502_RS11875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SYN7502_RS11895	COG0386	Belongs to the glutathione peroxidase family
SYN7502_RS11900	COG2094	Belongs to the DNA glycosylase MPG family
SYN7502_RS11940	COG0288	reversible hydration of carbon dioxide
SYN7502_RS11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYN7502_RS11950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SYN7502_RS11970	COG1811	Na channel or pump
SYN7502_RS11980	COG1191	sigma factor activity
SYN7502_RS11985	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SYN7502_RS11990	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SYN7502_RS12000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYN7502_RS12005	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS12030	COG2153	protein acetylation
SYN7502_RS12035	COG1175	transmembrane transport
SYN7502_RS12045	COG0284	orotidine-5'-phosphate decarboxylase activity
SYN7502_RS12050	COG1725	Transcriptional regulator
SYN7502_RS12090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SYN7502_RS12095	COG0049	tRNA binding
SYN7502_RS12100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SYN7502_RS12105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SYN7502_RS12110	COG0802	atpase or kinase
SYN7502_RS12120	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS12125	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS12130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SYN7502_RS12165	COG1192	Involved in chromosome partitioning
SYN7502_RS12175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS12185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SYN7502_RS12215	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS12230	COG1216	Glycosyl transferase, family 2
SYN7502_RS12230	COG0463	Glycosyl transferase, family 2
SYN7502_RS12235	COG2327	Polysaccharide pyruvyl transferase
SYN7502_RS12255	COG0463	Glycosyl transferase, family 2
SYN7502_RS12265	COG0420	3'-5' exonuclease activity
SYN7502_RS12275	COG1196	nuclear chromosome segregation
SYN7502_RS12300	COG4242	Belongs to the peptidase S51 family
SYN7502_RS12305	COG1136	(ABC) transporter
SYN7502_RS12305	COG0577	efflux transmembrane transporter activity
SYN7502_RS12315	COG0725	ABC transporter, periplasmic molybdate-binding protein
SYN7502_RS12330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN7502_RS12350	COG1121	(ABC) transporter
SYN7502_RS12355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYN7502_RS12360	COG0739	heme binding
SYN7502_RS12365	COG0303	'Molybdopterin
SYN7502_RS12370	COG0408	coproporphyrinogen oxidase activity
SYN7502_RS12410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SYN7502_RS12410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SYN7502_RS12415	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SYN7502_RS12430	COG1981	membrane
SYN7502_RS12450	COG0804	urea catabolic process
SYN7502_RS12460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SYN7502_RS12530	COG0686	Belongs to the AlaDH PNT family
SYN7502_RS12540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SYN7502_RS12550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SYN7502_RS12570	COG1662	PFAM IS1 transposase
SYN7502_RS12600	COG1054	Belongs to the UPF0176 family
SYN7502_RS12615	COG2010	Cytochrome c
SYN7502_RS12645	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SYN7502_RS12655	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SYN7502_RS12660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SYN7502_RS12675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SYN7502_RS12685	COG0561	phosphatase activity
SYN7502_RS12690	COG2890	protein-(glutamine-N5) methyltransferase activity
SYN7502_RS12715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SYN7502_RS12725	COG1090	epimerase
SYN7502_RS12740	COG0314	molybdopterin synthase activity
SYN7502_RS12750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SYN7502_RS12755	COG0673	inositol 2-dehydrogenase activity
SYN7502_RS12765	COG1187	pseudouridine synthase activity
SYN7502_RS12780	COG1022	Amp-dependent synthetase and ligase
SYN7502_RS12795	COG0497	DNA recombination
SYN7502_RS12810	COG3195	allantoin biosynthetic process
SYN7502_RS12810	COG3648	Uricase
SYN7502_RS12815	COG2351	hydroxyisourate hydrolase activity
SYN7502_RS12820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SYN7502_RS12830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYN7502_RS12835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYN7502_RS12840	COG0085	RNA polymerase activity
SYN7502_RS12845	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SYN7502_RS12850	COG1064	alcohol dehydrogenase
SYN7502_RS12865	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS12870	COG1489	DNA binding
SYN7502_RS12885	COG0006	proline dipeptidase activity
SYN7502_RS12890	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SYN7502_RS12900	COG0470	DNA polymerase III
SYN7502_RS12940	COG2884	Cell division ATP-binding protein ftsE
SYN7502_RS12950	COG0473	3-isopropylmalate dehydrogenase activity
SYN7502_RS12955	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYN7502_RS12970	COG0484	heat shock protein binding
SYN7502_RS12980	COG1162	GTPase activity
SYN7502_RS12985	COG2259	Doxx family
SYN7502_RS12990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYN7502_RS13000	COG1181	Belongs to the D-alanine--D-alanine ligase family
SYN7502_RS13005	COG0739	heme binding
SYN7502_RS13015	COG0673	inositol 2-dehydrogenase activity
SYN7502_RS13020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SYN7502_RS13035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SYN7502_RS13040	COG1842	Phage shock protein A
SYN7502_RS13045	COG0837	glucose binding
SYN7502_RS13055	COG1494	fructose-1,6-bisphosphatase
SYN7502_RS13065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SYN7502_RS13070	COG0346	lactoylglutathione lyase activity
SYN7502_RS13075	COG3781	membrane
SYN7502_RS13080	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SYN7502_RS13090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SYN7502_RS13110	COG0142	geranyltranstransferase activity
SYN7502_RS13120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SYN7502_RS13125	COG0028	Belongs to the TPP enzyme family
SYN7502_RS13185	COG0167	dihydroorotate dehydrogenase activity
SYN7502_RS13200	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SYN7502_RS13220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SYN7502_RS13225	COG0860	N-Acetylmuramoyl-L-alanine amidase
SYN7502_RS13225	COG2247	cell wall binding repeat
SYN7502_RS13235	COG2814	Major facilitator Superfamily
SYN7502_RS13240	COG1160	GTP binding
SYN7502_RS13255	COG0596	Alpha beta hydrolase
SYN7502_RS13265	COG0539	negative regulation of cytoplasmic translation
SYN7502_RS13280	COG0166	Belongs to the GPI family
SYN7502_RS13300	COG0616	signal peptide processing
SYN7502_RS13305	COG1316	TRANSCRIPTIONal
SYN7502_RS13315	COG3001	Fructosamine kinase
SYN7502_RS13335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SYN7502_RS13340	COG0459	protein refolding
SYN7502_RS13345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SYN7502_RS13350	COG0602	queuosine metabolic process
SYN7502_RS13365	COG1573	uracil-dna glycosylase
SYN7502_RS13370	COG1136	(ABC) transporter
SYN7502_RS13370	COG0577	efflux transmembrane transporter activity
SYN7502_RS13375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SYN7502_RS13390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYN7502_RS13405	COG0829	nickel cation binding
SYN7502_RS13410	COG0831	urea catabolic process
SYN7502_RS13440	COG0725	ABC transporter, periplasmic molybdate-binding protein
SYN7502_RS13445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SYN7502_RS13475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYN7502_RS13500	COG1132	(ABC) transporter
SYN7502_RS13555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SYN7502_RS13560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SYN7502_RS13565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SYN7502_RS13570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SYN7502_RS13585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SYN7502_RS13600	COG1366	Belongs to the anti-sigma-factor antagonist family
SYN7502_RS13605	COG2208	phosphoserine phosphatase activity
SYN7502_RS13605	COG2770	Histidine kinase
SYN7502_RS13625	COG1968	undecaprenyl-diphosphatase activity
SYN7502_RS13640	COG1619	proteins homologs of microcin C7 resistance protein MccF
SYN7502_RS13645	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SYN7502_RS13660	COG2084	Dehydrogenase
SYN7502_RS13675	COG0318	PFAM AMP-dependent synthetase and ligase
SYN7502_RS13680	COG0747	negative chemotaxis
SYN7502_RS13685	COG1136	(ABC) transporter
SYN7502_RS13690	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SYN7502_RS13700	COG1132	(ABC) transporter
SYN7502_RS13705	COG0135	phosphoribosylanthranilate isomerase activity
SYN7502_RS13710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SYN7502_RS13715	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SYN7502_RS13720	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYN7502_RS13725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SYN7502_RS13730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SYN7502_RS13735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYN7502_RS13760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SYN7502_RS13780	COG0514	ATP-dependent DNA helicase (RecQ)
SYN7502_RS13900	COG1570	exodeoxyribonuclease VII activity
SYN7502_RS13905	COG1722	exodeoxyribonuclease VII activity
SYN7502_RS13925	COG1468	defense response to virus
SYN7502_RS13925	COG1518	maintenance of DNA repeat elements
SYN7502_RS14070	COG0514	ATP-dependent DNA helicase (RecQ)
SYN7502_RS14075	COG2062	phosphohistidine phosphatase, SixA
SYN7502_RS14085	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYN7502_RS14090	COG0515	serine threonine protein kinase
SYN7502_RS14090	COG3266	domain, Protein
SYN7502_RS14095	COG0024	Methionine aminopeptidase
SYN7502_RS14110	COG1185	polyribonucleotide nucleotidyltransferase activity
SYN7502_RS14135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYN7502_RS14140	COG0830	nickel cation binding
SYN7502_RS14145	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SYN7502_RS14180	COG0678	peroxiredoxin activity
SYN7502_RS14190	COG0395	ABC-type sugar transport system, permease component
SYN7502_RS14205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYN7502_RS14210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SYN7502_RS14215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SYN7502_RS14230	COG0482	sulfurtransferase activity
SYN7502_RS14245	COG0003	Pfam Anion-transporting ATPase
SYN7502_RS14260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SYN7502_RS14270	COG4636	protein conserved in cyanobacteria
SYN7502_RS14280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SYN7502_RS14290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SYN7502_RS14300	COG0646	methionine synthase
SYN7502_RS14300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SYN7502_RS14320	COG0204	Acyl-transferase
SYN7502_RS14320	COG0318	PFAM AMP-dependent synthetase and ligase
SYN7502_RS14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYN7502_RS14335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SYN7502_RS14345	COG1116	anion transmembrane transporter activity
SYN7502_RS14355	COG1982	Orn Lys Arg decarboxylase major
SYN7502_RS14360	COG0357	Ribosomal RNA small subunit methyltransferase G
SYN7502_RS14375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SYN7502_RS14380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYN7502_RS14390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SYN7502_RS14395	COG0443	Heat shock 70 kDa protein
SYN7502_RS14415	COG0653	protein targeting
SYN7502_RS14420	COG3239	Fatty acid desaturase
SYN7502_RS14430	COG1309	transcriptional regulator
SYN7502_RS14440	COG0312	modulator of DNA gyrase
SYN7502_RS14445	COG1361	Conserved repeat domain
SYN7502_RS14450	COG0625	glutathione transferase activity
SYN7502_RS14455	COG0215	cysteine-tRNA ligase activity
SYN7502_RS14475	COG0697	spore germination
SYN7502_RS14490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYN7502_RS14495	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYN7502_RS14515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYN7502_RS14520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYN7502_RS14550	COG1595	DNA-templated transcription, initiation
SYN7502_RS14560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SYN7502_RS14570	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYN7502_RS14580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SYN7502_RS14610	COG2124	cytochrome p450
SYN7502_RS14615	COG3615	Tellurite resistance protein tehB
SYN7502_RS14615	COG0500	methyltransferase
SYN7502_RS14630	COG1570	exodeoxyribonuclease VII activity
SYN7502_RS14635	COG0667	Aldo Keto reductase
SYN7502_RS14640	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SYN7502_RS14655	COG0415	Belongs to the DNA photolyase family
SYN7502_RS14665	COG1132	(ABC) transporter
SYN7502_RS14710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SYN7502_RS14720	COG3659	wide pore channel activity
SYN7502_RS14725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SYN7502_RS14730	COG1116	anion transmembrane transporter activity
SYN7502_RS14735	COG0318	PFAM AMP-dependent synthetase and ligase
SYN7502_RS14750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SYN7502_RS14755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYN7502_RS14760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SYN7502_RS14770	COG0563	adenylate kinase activity
SYN7502_RS14775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYN7502_RS14775	COG0758	DNA mediated transformation
SYN7502_RS14795	COG0544	peptidyl-prolyl cis-trans isomerase activity
SYN7502_RS14800	COG0740	serine-type endopeptidase activity
SYN7502_RS14805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SYN7502_RS14810	COG3688	RNA-binding protein containing a PIN domain
SYN7502_RS14875	COG0149	triose-phosphate isomerase activity
SYN7502_RS14880	COG0513	Belongs to the DEAD box helicase family
SYN7502_RS14890	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SYN7502_RS14900	COG0372	Belongs to the citrate synthase family
SYN7502_RS14915	COG1132	(ABC) transporter
SYN7502_RS14920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SYN7502_RS14935	COG0018	arginyl-trna synthetase
SYN7502_RS14960	COG1132	(ABC) transporter
SYN7502_RS14970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SYN7502_RS14995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SYN7502_RS15010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SYN7502_RS15015	COG0443	Heat shock 70 kDa protein
SYN7502_RS15020	COG0735	belongs to the Fur family
SYN7502_RS15030	COG0719	Fe-S assembly protein
SYN7502_RS15040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SYN7502_RS15065	COG1215	transferase activity, transferring glycosyl groups
SYN7502_RS15070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SYN7502_RS15070	COG2755	lipolytic protein G-D-S-L family
SYN7502_RS15080	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS15120	COG0037	tRNA processing
SYN7502_RS15140	COG0052	Belongs to the universal ribosomal protein uS2 family
SYN7502_RS15145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SYN7502_RS15150	COG0023	Translation Initiation Factor
SYN7502_RS15155	COG0004	ammonium transporteR
SYN7502_RS15180	COG0305	Participates in initiation and elongation during chromosome replication
SYN7502_RS15180	COG0305	Participates in initiation and elongation during chromosome replication
SYN7502_RS15180	COG1372	Participates in initiation and elongation during chromosome replication
SYN7502_RS15180	COG1372	Participates in initiation and elongation during chromosome replication
SYN7502_RS15195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SYN7502_RS15205	COG1131	(ABC) transporter
SYN7502_RS15250	COG1366	Belongs to the anti-sigma-factor antagonist family
SYN7502_RS15260	COG1366	Belongs to the anti-sigma-factor antagonist family
SYN7502_RS15270	COG0302	gtp cyclohydrolase
SYN7502_RS15275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYN7502_RS15300	COG1530	ribonuclease E activity
SYN7502_RS15305	COG0406	alpha-ribazole phosphatase activity
SYN7502_RS15310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SYN7502_RS15315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SYN7502_RS15320	COG0416	fatty acid biosynthetic process
SYN7502_RS15330	COG0426	domain, Protein
SYN7502_RS15330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYN7502_RS15430	COG2135	peptidase activity
SYN7502_RS15455	COG1662	PFAM IS1 transposase
SYN7502_RS15510	COG1309	transcriptional regulator
SYN7502_RS15515	COG0300	oxidoreductase activity
SYN7502_RS15530	COG2258	MOSC domain
SYN7502_RS15535	COG1733	regulation of RNA biosynthetic process
SYN7502_RS15630	COG1741	Belongs to the pirin family
SYN7502_RS15650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SYN7502_RS15655	COG1335	isochorismatase
SYN7502_RS15675	COG2197	response regulator
SYN7502_RS15680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYN7502_RS15715	COG1690	Belongs to the RtcB family
SYN7502_RS15720	COG0542	response to heat
SYN7502_RS15750	COG0697	spore germination
SYN7502_RS15775	COG0346	lactoylglutathione lyase activity
SYN7502_RS15810	COG0745	RESPONSE REGULATOR receiver
SYN7502_RS15815	COG5002	protein histidine kinase activity
SYN7502_RS15815	COG3850	Histidine kinase
SYN7502_RS15820	COG3852	Histidine kinase
SYN7502_RS15860	COG3657	addiction module killer protein
SYN7502_RS15865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SYN7502_RS15885	COG0318	PFAM AMP-dependent synthetase and ligase
SYN7502_RS15905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYN7502_RS15960	COG0110	maltose O-acetyltransferase activity
SYN7502_RS16000	COG1216	Glycosyl transferase, family 2
SYN7502_RS16005	COG1216	Glycosyl transferase, family 2
SYN7502_RS16005	COG1442	glycosyl transferase family 8
SYN7502_RS16055	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SYN7502_RS16070	COG0328	RNA-DNA hybrid ribonuclease activity
SYN7502_RS16080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SYN7502_RS16085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SYN7502_RS16095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SYN7502_RS16100	COG1012	belongs to the aldehyde dehydrogenase family
SYN7502_RS16105	COG5322	oxidoreductase activity
SYN7502_RS16110	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYN7502_RS16115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYN7502_RS16125	COG1748	Saccharopine dehydrogenase
SYN7502_RS16130	COG0051	transcription antitermination factor activity, RNA binding
SYN7502_RS16135	COG0297	glycogen (starch) synthase activity
SYN7502_RS16145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SYN7502_RS16155	COG1104	cysteine desulfurase activity
SYN7502_RS16165	COG0484	heat shock protein binding
SYN7502_RS16175	COG4948	Mandelate Racemase Muconate Lactonizing
SYN7502_RS16195	COG0237	dephospho-CoA kinase activity
SYN7502_RS16200	COG0237	dephospho-CoA kinase activity
SYN7502_RS16205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SYN7502_RS16210	COG1413	lyase activity
SYN7502_RS16215	COG1413	lyase activity
SYN7502_RS16240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYN7502_RS16240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYN7502_RS16255	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYN7502_RS16265	COG1480	7TM receptor with intracellular HD hydrolase
SYN7502_RS16280	COG1492	cobalamin metabolic process
SYN7502_RS16300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SYN7502_RS16305	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SYN7502_RS16315	COG0793	Belongs to the peptidase S41A family
SYN7502_RS16320	COG0583	DNA-binding transcription factor activity
SYN7502_RS16325	COG1028	Short-chain dehydrogenase reductase Sdr
SYN7502_RS16335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SYN7502_RS16350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYN7502_RS16365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYN7502_RS16385	COG0477	Major facilitator Superfamily
SYN7502_RS16395	COG5002	protein histidine kinase activity
SYN7502_RS16395	COG0784	Response regulator, receiver
SYN7502_RS16400	COG0277	FAD linked oxidase domain protein
SYN7502_RS16410	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SYN7502_RS16450	COG0463	Glycosyl transferase, family 2
SYN7502_RS16455	COG1216	Glycosyl transferase, family 2
SYN7502_RS16460	COG0556	nucleotide-excision repair
SYN7502_RS16465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SYN7502_RS16465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYN7502_RS16480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SYN7502_RS16500	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SYN7502_RS16515	COG0857	belongs to the CobB CobQ family
SYN7502_RS16520	COG3842	ATPase activity
SYN7502_RS16525	COG0501	Belongs to the peptidase M48B family
SYN7502_RS16535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SYN7502_RS16545	COG1215	transferase activity, transferring glycosyl groups
SYN7502_RS16550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SYN7502_RS16555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SYN7502_RS16560	COG0501	Belongs to the peptidase M48B family
SYN7502_RS16580	COG0788	formyltetrahydrofolate deformylase activity
SYN7502_RS16585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SYN7502_RS16600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SYN7502_RS16605	COG2172	sigma factor antagonist activity
SYN7502_RS16620	COG0824	Thioesterase
SYN7502_RS16625	COG2046	Belongs to the sulfate adenylyltransferase family
SYN7502_RS16630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SYN7502_RS16645	COG0419	ATPase involved in DNA repair
SYN7502_RS16695	COG4974	Belongs to the 'phage' integrase family
SYN7502_RS16750	COG1077	Cell shape determining protein MreB Mrl
SYN7502_RS16755	COG1792	Involved in formation and maintenance of cell shape
SYN7502_RS16760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SYN7502_RS16775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SYN7502_RS16785	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SYN7502_RS16805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SYN7502_RS16810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SYN7502_RS16815	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SYN7502_RS16840	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
SYN7502_RS16845	COG0633	Ferredoxin
SYN7502_RS16850	COG5002	protein histidine kinase activity
SYN7502_RS16860	COG1122	ATPase activity
SYN7502_RS16885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYN7502_RS16895	COG0617	tRNA 3'-terminal CCA addition
SYN7502_RS16900	COG0509	glycine decarboxylation via glycine cleavage system
SYN7502_RS16905	COG0861	Integral membrane protein TerC family
SYN7502_RS16915	COG0723	plastoquinol--plastocyanin reductase activity
SYN7502_RS16925	COG0411	ABC transporter
SYN7502_RS16935	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SYN7502_RS16945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SYN7502_RS16965	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SYN7502_RS16975	COG0436	Aminotransferase
SYN7502_RS16985	COG2205	protein histidine kinase activity
SYN7502_RS16985	COG0784	Response regulator, receiver
SYN7502_RS17000	COG1294	oxidase, subunit
SYN7502_RS17005	COG1271	oxidase subunit
SYN7502_RS17035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SYN7502_RS17045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYN7502_RS17055	COG0438	transferase activity, transferring glycosyl groups
SYN7502_RS17070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SYN7502_RS17075	COG1657	PFAM Prenyltransferase squalene oxidase
SYN7502_RS17095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYN7502_RS17100	COG2205	protein histidine kinase activity
SYN7502_RS17110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SYN7502_RS17115	COG0504	CTP synthase activity
SYN7502_RS17130	COG2003	Belongs to the UPF0758 family
SYN7502_RS17140	COG0247	lactate metabolic process
SYN7502_RS17180	COG0157	Belongs to the NadC ModD family
SYN7502_RS17185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SYN7502_RS17195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYN7502_RS17205	COG0525	valine-tRNA ligase activity
SYN7502_RS17230	COG0557	exoribonuclease II activity
SYN7502_RS17240	COG0572	uridine kinase
SYN7502_RS17270	COG0210	DNA helicase
SYN7502_RS17285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYN7502_RS17300	COG2217	Heavy metal translocating P-type atpase
SYN7502_RS17310	COG1598	PFAM Uncharacterised protein family UPF0150
SYN7502_RS17345	COG0469	pyruvate kinase activity
SYN7502_RS17355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SYN7502_RS17360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SYN7502_RS17365	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SYN7502_RS17365	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SYN7502_RS17370	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SYN7502_RS17380	COG0629	single-stranded DNA binding
SYN7502_RS17385	COG0009	L-threonylcarbamoyladenylate synthase
SYN7502_RS17400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SYN7502_RS17410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYN7502_RS17425	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SYN7502_RS17450	COG4956	integral membrane protein (PIN domain superfamily)
SYN7502_RS17455	COG0322	excinuclease ABC activity
SYN7502_RS17460	COG1742	UPF0060 membrane protein
SYN7502_RS17480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SYN7502_RS17485	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SYN7502_RS17500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SYN7502_RS17505	COG0235	Class ii aldolase
SYN7502_RS17515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYN7502_RS17520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SYN7502_RS17525	COG0460	homoserine dehydrogenase
SYN7502_RS17530	COG3118	belongs to the thioredoxin family
SYN7502_RS17535	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SYN7502_RS17545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYN7502_RS17565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SYN7502_RS17570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SYN7502_RS17575	COG1028	Short-chain dehydrogenase reductase Sdr
SYN7502_RS17590	COG0435	Glutathione S-transferase
SYN7502_RS17795	COG1525	nuclease
SYN7502_RS17795	COG0737	Belongs to the 5'-nucleotidase family
SYN7502_RS17795	COG4085	toxin activity
SYN7502_RS17860	COG0538	isocitrate dehydrogenase activity
SYN7502_RS18010	COG5001	Diguanylate cyclase
SYN7502_RS18040	COG2205	protein histidine kinase activity
SYN7502_RS18045	COG1649	PFAM Uncharacterised BCR, COG1649
SYN7502_RS18055	COG4968	Prepilin-type N-terminal cleavage methylation domain
SYN7502_RS18080	COG5001	Diguanylate cyclase
SYN7502_RS18080	COG4251	negative regulation of phosphorylation
SYN7502_RS18080	COG3706	GGDEF domain
SYN7502_RS18080	COG2203	Gaf domain
SYN7502_RS18105	COG0515	serine threonine protein kinase
SYN7502_RS18105	COG3266	domain, Protein
SYN7502_RS18110	COG3266	domain, Protein
SYN7502_RS18110	COG2911	Protein conserved in bacteria
SYN7502_RS18110	COG1361	Conserved repeat domain
SYN7502_RS18115	COG0840	transmembrane signaling receptor activity
SYN7502_RS18125	COG0484	heat shock protein binding
SYN7502_RS18130	COG0784	Response regulator, receiver
SYN7502_RS18130	COG5002	protein histidine kinase activity
SYN7502_RS18140	COG0784	Response regulator, receiver
SYN7502_RS18140	COG2205	protein histidine kinase activity
SYN7502_RS18155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SYN7502_RS18170	COG5002	protein histidine kinase activity
SYN7502_RS18170	COG0784	Response regulator, receiver
SYN7502_RS18170	COG2205	protein histidine kinase activity
SYN7502_RS18175	COG0784	Response regulator, receiver
SYN7502_RS18175	COG5002	protein histidine kinase activity
SYN7502_RS18195	COG0515	serine threonine protein kinase
SYN7502_RS18195	COG1357	PFAM Pentapeptide repeats (8 copies)
SYN7502_RS18210	COG2203	Gaf domain
SYN7502_RS18210	COG3706	GGDEF domain
SYN7502_RS18210	COG4251	negative regulation of phosphorylation
SYN7502_RS18210	COG5001	Diguanylate cyclase
SYN7502_RS18275	COG2205	protein histidine kinase activity
SYN7502_RS18275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYN7502_RS18280	COG0784	Response regulator, receiver
SYN7502_RS18280	COG5002	protein histidine kinase activity
SYN7502_RS18300	COG3751	2OG-Fe(II) oxygenase superfamily
SYN7502_RS18310	COG0515	serine threonine protein kinase
SYN7502_RS18315	COG0442	prolyl-tRNA aminoacylation
SYN7502_RS18325	COG2205	protein histidine kinase activity
SYN7502_RS18325	COG0784	Response regulator, receiver
SYN7502_RS18345	COG0739	heme binding
SYN7502_RS18345	COG0741	lytic transglycosylase activity
SYN7502_RS18345	COG1196	nuclear chromosome segregation
SYN7502_RS18375	COG2198	Histidine kinase
SYN7502_RS18375	COG0784	Response regulator, receiver
SYN7502_RS18375	COG0643	Histidine kinase
SYN7502_RS18475	COG1054	Belongs to the UPF0176 family
SYN7502_RS18480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYN7502_RS18520	COG5001	Diguanylate cyclase
SYN7502_RS18520	COG4251	negative regulation of phosphorylation
SYN7502_RS18520	COG3706	GGDEF domain
SYN7502_RS18520	COG2203	Gaf domain
SYN7502_RS18540	COG4251	negative regulation of phosphorylation
SYN7502_RS18540	COG3706	GGDEF domain
SYN7502_RS18540	COG2203	Gaf domain
SYN7502_RS18540	COG5001	Diguanylate cyclase