locus-tag	class	description
SynPROS71_RS00005	COG0592	DNA-directed DNA polymerase activity
SynPROS71_RS00015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynPROS71_RS00020	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SynPROS71_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynPROS71_RS00035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynPROS71_RS00050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynPROS71_RS00055	COG0552	protein localization to endoplasmic reticulum
SynPROS71_RS00060	COG2208	phosphoserine phosphatase activity
SynPROS71_RS00065	COG0165	Argininosuccinate lyase
SynPROS71_RS00070	COG0724	RNA recognition motif
SynPROS71_RS00075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynPROS71_RS00085	COG2081	HI0933 family
SynPROS71_RS00090	COG1459	type II secretion system
SynPROS71_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynPROS71_RS00105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynPROS71_RS00110	COG0484	heat shock protein binding
SynPROS71_RS00120	COG1162	GTPase activity
SynPROS71_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynPROS71_RS00130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynPROS71_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynPROS71_RS00140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynPROS71_RS00145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynPROS71_RS00150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynPROS71_RS00155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynPROS71_RS00160	COG0511	ligase activity, forming carbon-carbon bonds
SynPROS71_RS00165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynPROS71_RS00235	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynPROS71_RS00240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynPROS71_RS00240	COG0519	Catalyzes the synthesis of GMP from XMP
SynPROS71_RS00255	COG0768	penicillin binding
SynPROS71_RS00260	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS00265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynPROS71_RS00275	COG2022	thiamine diphosphate biosynthetic process
SynPROS71_RS00290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynPROS71_RS00295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynPROS71_RS00300	COG2385	sporulation resulting in formation of a cellular spore
SynPROS71_RS00305	COG1215	transferase activity, transferring glycosyl groups
SynPROS71_RS00310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynPROS71_RS00320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynPROS71_RS00325	COG0740	serine-type endopeptidase activity
SynPROS71_RS00330	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynPROS71_RS00335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynPROS71_RS00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynPROS71_RS00345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynPROS71_RS00355	COG0037	tRNA processing
SynPROS71_RS00375	COG0556	nucleotide-excision repair
SynPROS71_RS00395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynPROS71_RS00400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynPROS71_RS00435	COG2082	Precorrin-8x methylmutase
SynPROS71_RS00440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynPROS71_RS00455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynPROS71_RS00500	COG0436	Aminotransferase
SynPROS71_RS00510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynPROS71_RS00575	COG1091	dTDP-4-dehydrorhamnose reductase activity
SynPROS71_RS00580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynPROS71_RS00590	COG1088	dTDP-glucose 4,6-dehydratase activity
SynPROS71_RS00595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynPROS71_RS00600	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynPROS71_RS00620	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS00670	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS00720	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS00735	COG1216	Glycosyl transferase, family 2
SynPROS71_RS00745	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS00780	COG0653	protein targeting
SynPROS71_RS00785	COG1045	serine acetyltransferase
SynPROS71_RS00790	COG1725	Transcriptional regulator
SynPROS71_RS00800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynPROS71_RS00805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynPROS71_RS00810	COG1372	Participates in initiation and elongation during chromosome replication
SynPROS71_RS00810	COG0187	DNA topoisomerase II activity
SynPROS71_RS00820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynPROS71_RS00825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynPROS71_RS00830	COG0386	Belongs to the glutathione peroxidase family
SynPROS71_RS00835	COG2239	Acts as a magnesium transporter
SynPROS71_RS00840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS00910	COG1070	Carbohydrate kinase
SynPROS71_RS00920	COG0802	atpase or kinase
SynPROS71_RS00925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynPROS71_RS00930	COG0586	Pfam SNARE associated Golgi protein
SynPROS71_RS00935	COG0629	single-stranded DNA binding
SynPROS71_RS00945	COG1792	Involved in formation and maintenance of cell shape
SynPROS71_RS00965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynPROS71_RS00985	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynPROS71_RS00990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynPROS71_RS00995	COG0515	serine threonine protein kinase
SynPROS71_RS00995	COG1357	PFAM Pentapeptide repeats (8 copies)
SynPROS71_RS01000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynPROS71_RS01005	COG2255	four-way junction helicase activity
SynPROS71_RS01015	COG1473	amidohydrolase
SynPROS71_RS01030	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynPROS71_RS01050	COG0463	Glycosyl transferase, family 2
SynPROS71_RS01060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynPROS71_RS01065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynPROS71_RS01070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynPROS71_RS01075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS01080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynPROS71_RS01085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynPROS71_RS01085	COG0662	Cupin 2, conserved barrel domain protein
SynPROS71_RS01090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynPROS71_RS01100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynPROS71_RS01105	COG0571	ribonuclease III activity
SynPROS71_RS01135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SynPROS71_RS01140	COG0058	SHG alpha-glucan phosphorylase activity
SynPROS71_RS01145	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SynPROS71_RS01150	COG0475	glutathione-regulated potassium exporter activity
SynPROS71_RS01170	COG0277	FAD linked oxidase domain protein
SynPROS71_RS01180	COG0247	lactate metabolic process
SynPROS71_RS01185	COG0538	isocitrate dehydrogenase activity
SynPROS71_RS01190	COG0463	Glycosyl transferase, family 2
SynPROS71_RS01205	COG5398	heme oxygenase
SynPROS71_RS01220	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS01230	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS01235	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS01255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynPROS71_RS01265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynPROS71_RS01270	COG0617	tRNA 3'-terminal CCA addition
SynPROS71_RS01285	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynPROS71_RS01305	COG0709	Synthesizes selenophosphate from selenide and ATP
SynPROS71_RS01310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynPROS71_RS01340	COG1083	cytidylyl-transferase
SynPROS71_RS01350	COG2089	acid synthase
SynPROS71_RS01380	COG3959	Transketolase, thiamine diphosphate binding domain
SynPROS71_RS01385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynPROS71_RS01450	COG0124	histidyl-tRNA synthetase
SynPROS71_RS01455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynPROS71_RS01490	COG4447	cellulose binding
SynPROS71_RS01495	COG1773	rubredoxin
SynPROS71_RS01500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS01505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS01510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS01515	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynPROS71_RS01520	COG3842	ATPase activity
SynPROS71_RS01530	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynPROS71_RS01530	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynPROS71_RS01540	COG0494	nUDIX hydrolase
SynPROS71_RS01545	COG0415	Belongs to the DNA photolyase family
SynPROS71_RS01550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynPROS71_RS01575	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynPROS71_RS01580	COG0131	Imidazoleglycerol-phosphate dehydratase
SynPROS71_RS01585	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynPROS71_RS01600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynPROS71_RS01620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynPROS71_RS01625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynPROS71_RS01635	COG0354	folic acid binding
SynPROS71_RS01640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynPROS71_RS01655	COG1253	flavin adenine dinucleotide binding
SynPROS71_RS01660	COG0673	inositol 2-dehydrogenase activity
SynPROS71_RS01680	COG0343	queuine tRNA-ribosyltransferase activity
SynPROS71_RS01685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynPROS71_RS01705	COG0138	bifunctional purine biosynthesis protein purh
SynPROS71_RS01720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynPROS71_RS01725	COG0004	ammonium transporteR
SynPROS71_RS01730	COG1489	DNA binding
SynPROS71_RS01735	COG0728	peptidoglycan biosynthetic process
SynPROS71_RS01760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynPROS71_RS01765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynPROS71_RS01770	COG1058	Belongs to the CinA family
SynPROS71_RS01770	COG1546	Belongs to the CinA family
SynPROS71_RS01775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynPROS71_RS01780	COG0066	3-isopropylmalate dehydratase activity
SynPROS71_RS01815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynPROS71_RS01820	COG0193	aminoacyl-tRNA hydrolase activity
SynPROS71_RS01835	COG4372	Transposase
SynPROS71_RS01840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynPROS71_RS01845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynPROS71_RS01855	COG0717	Belongs to the dCTP deaminase family
SynPROS71_RS01865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynPROS71_RS01885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynPROS71_RS01900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynPROS71_RS01925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynPROS71_RS01945	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynPROS71_RS01960	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynPROS71_RS02010	COG2274	protein secretion by the type I secretion system
SynPROS71_RS02050	COG2094	Belongs to the DNA glycosylase MPG family
SynPROS71_RS02055	COG0540	Belongs to the ATCase OTCase family
SynPROS71_RS02095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynPROS71_RS02110	COG0529	Catalyzes the synthesis of activated sulfate
SynPROS71_RS02110	COG2046	Belongs to the sulfate adenylyltransferase family
SynPROS71_RS02115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynPROS71_RS02120	COG0800	Aldolase
SynPROS71_RS02130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynPROS71_RS02140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynPROS71_RS02145	COG2226	methyltransferase
SynPROS71_RS02150	COG4175	Glycine betaine
SynPROS71_RS02155	COG4176	ABC-type proline glycine betaine transport system permease component
SynPROS71_RS02160	COG2113	Glycine betaine
SynPROS71_RS02165	COG0385	Bile acid
SynPROS71_RS02175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynPROS71_RS02185	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynPROS71_RS02190	COG0436	Aminotransferase
SynPROS71_RS02200	COG1530	ribonuclease E activity
SynPROS71_RS02205	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynPROS71_RS02220	COG2226	methyltransferase
SynPROS71_RS02225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynPROS71_RS02230	COG0051	transcription antitermination factor activity, RNA binding
SynPROS71_RS02235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynPROS71_RS02240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynPROS71_RS02245	COG0049	tRNA binding
SynPROS71_RS02250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynPROS71_RS02265	COG0070	glutamate synthase
SynPROS71_RS02265	COG0069	glutamate synthase activity
SynPROS71_RS02265	COG0067	glutamate synthase
SynPROS71_RS02295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynPROS71_RS02320	COG2885	chlorophyll binding
SynPROS71_RS02325	COG2885	chlorophyll binding
SynPROS71_RS02360	COG0463	Glycosyl transferase, family 2
SynPROS71_RS02385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynPROS71_RS02395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynPROS71_RS02400	COG0254	rRNA binding
SynPROS71_RS02405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynPROS71_RS02410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynPROS71_RS02415	COG0101	tRNA pseudouridine synthase activity
SynPROS71_RS02420	COG0203	ribosomal protein L17
SynPROS71_RS02425	COG0202	RNA polymerase activity
SynPROS71_RS02430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynPROS71_RS02435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynPROS71_RS02440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynPROS71_RS02445	COG0563	adenylate kinase activity
SynPROS71_RS02450	COG0201	protein transport
SynPROS71_RS02455	COG0200	Binds to the 23S rRNA
SynPROS71_RS02460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynPROS71_RS02465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynPROS71_RS02470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynPROS71_RS02475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynPROS71_RS02480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynPROS71_RS02485	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynPROS71_RS02490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynPROS71_RS02495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynPROS71_RS02500	COG0255	Belongs to the universal ribosomal protein uL29 family
SynPROS71_RS02505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynPROS71_RS02510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynPROS71_RS02515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynPROS71_RS02520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynPROS71_RS02525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynPROS71_RS02530	COG0089	rRNA binding
SynPROS71_RS02535	COG0088	Forms part of the polypeptide exit tunnel
SynPROS71_RS02540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynPROS71_RS02555	COG3854	ATPases associated with a variety of cellular activities
SynPROS71_RS02570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynPROS71_RS02590	COG0287	Prephenate dehydrogenase
SynPROS71_RS02600	COG3001	Fructosamine kinase
SynPROS71_RS02620	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynPROS71_RS02625	COG1606	tRNA processing
SynPROS71_RS02630	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynPROS71_RS02635	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynPROS71_RS02645	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynPROS71_RS02650	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynPROS71_RS02655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynPROS71_RS02665	COG5002	protein histidine kinase activity
SynPROS71_RS02670	COG0772	Belongs to the SEDS family
SynPROS71_RS02675	COG0489	protein tyrosine kinase activity
SynPROS71_RS02680	COG0408	coproporphyrinogen oxidase activity
SynPROS71_RS02725	COG0667	Aldo Keto reductase
SynPROS71_RS02735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynPROS71_RS02740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynPROS71_RS02745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynPROS71_RS02745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynPROS71_RS02750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynPROS71_RS02755	COG1413	lyase activity
SynPROS71_RS02870	COG0237	dephospho-CoA kinase activity
SynPROS71_RS02910	COG1070	Carbohydrate kinase
SynPROS71_RS02915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynPROS71_RS02920	COG0546	phosphoglycolate phosphatase activity
SynPROS71_RS02925	COG0539	negative regulation of cytoplasmic translation
SynPROS71_RS02930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynPROS71_RS02955	COG0589	response to stress
SynPROS71_RS02970	COG2890	protein-(glutamine-N5) methyltransferase activity
SynPROS71_RS02975	COG0009	L-threonylcarbamoyladenylate synthase
SynPROS71_RS02995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynPROS71_RS03000	COG2894	cell division
SynPROS71_RS03005	COG0850	regulation of cytokinetic process
SynPROS71_RS03010	COG1078	dGTPase activity
SynPROS71_RS03015	COG0793	Belongs to the peptidase S41A family
SynPROS71_RS03020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynPROS71_RS03025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynPROS71_RS03060	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynPROS71_RS03065	COG0235	Class ii aldolase
SynPROS71_RS03070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynPROS71_RS03085	COG0514	ATP-dependent DNA helicase (RecQ)
SynPROS71_RS03090	COG1705	Flagellar rod assembly protein muramidase FlgJ
SynPROS71_RS03090	COG1388	LysM domain
SynPROS71_RS03095	COG1012	belongs to the aldehyde dehydrogenase family
SynPROS71_RS03105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynPROS71_RS03110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SynPROS71_RS03130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynPROS71_RS03155	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynPROS71_RS03175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynPROS71_RS03190	COG1376	ErfK ybiS ycfS ynhG family protein
SynPROS71_RS03195	COG1160	GTP binding
SynPROS71_RS03200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynPROS71_RS03210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynPROS71_RS03215	COG1799	cell septum assembly
SynPROS71_RS03220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynPROS71_RS03225	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS03235	COG1381	Involved in DNA repair and RecF pathway recombination
SynPROS71_RS03240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynPROS71_RS03245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynPROS71_RS03250	COG0321	lipoyl(octanoyl) transferase activity
SynPROS71_RS03255	COG1022	Amp-dependent synthetase and ligase
SynPROS71_RS03270	COG0531	amino acid
SynPROS71_RS03275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynPROS71_RS03280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynPROS71_RS03300	COG3239	Fatty acid desaturase
SynPROS71_RS03310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SynPROS71_RS03325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynPROS71_RS03375	COG1104	cysteine desulfurase activity
SynPROS71_RS03400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynPROS71_RS03405	COG0579	oxidoreductase
SynPROS71_RS03420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynPROS71_RS03435	COG2095	MarC family integral membrane protein
SynPROS71_RS03440	COG0181	hydroxymethylbilane synthase activity
SynPROS71_RS03465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS03470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynPROS71_RS03480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynPROS71_RS03495	COG0629	single-stranded DNA binding
SynPROS71_RS03505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynPROS71_RS03510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynPROS71_RS03520	COG0442	prolyl-tRNA aminoacylation
SynPROS71_RS03530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynPROS71_RS03550	COG0681	Belongs to the peptidase S26 family
SynPROS71_RS03575	COG0768	penicillin binding
SynPROS71_RS03580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynPROS71_RS03590	COG0415	Belongs to the DNA photolyase family
SynPROS71_RS03600	COG0233	cytoplasmic translational termination
SynPROS71_RS03605	COG0528	UMP kinase activity
SynPROS71_RS03620	COG2226	methyltransferase
SynPROS71_RS03630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS03635	COG0028	Belongs to the TPP enzyme family
SynPROS71_RS03655	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynPROS71_RS03660	COG1496	oxidoreductase activity
SynPROS71_RS03670	COG0539	negative regulation of cytoplasmic translation
SynPROS71_RS03680	COG3396	Phenylacetate-CoA oxygenase
SynPROS71_RS03685	COG5322	oxidoreductase activity
SynPROS71_RS03690	COG0825	malonyl-CoA metabolic process
SynPROS71_RS03700	COG0302	gtp cyclohydrolase
SynPROS71_RS03710	COG0135	phosphoribosylanthranilate isomerase activity
SynPROS71_RS03715	COG0517	IMP dehydrogenase activity
SynPROS71_RS03715	COG1994	Peptidase M50
SynPROS71_RS03720	COG0095	Lipoate-protein ligase
SynPROS71_RS03725	COG0730	response to heat
SynPROS71_RS03760	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynPROS71_RS03765	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynPROS71_RS03770	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynPROS71_RS03785	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynPROS71_RS03790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynPROS71_RS03795	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynPROS71_RS03800	COG1850	ribulose-bisphosphate carboxylase activity
SynPROS71_RS03805	COG4451	ribulose bisphosphate carboxylase, small
SynPROS71_RS03835	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynPROS71_RS03840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynPROS71_RS03845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS03875	COG0251	oxidation-reduction process
SynPROS71_RS03880	COG3842	ATPase activity
SynPROS71_RS03885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynPROS71_RS03890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynPROS71_RS03895	COG1132	(ABC) transporter
SynPROS71_RS03905	COG0456	acetyltransferase
SynPROS71_RS03920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynPROS71_RS03925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynPROS71_RS03945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynPROS71_RS03950	COG0811	peptide transport
SynPROS71_RS03980	COG1845	cytochrome c oxidase, subunit III
SynPROS71_RS03985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynPROS71_RS03990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SynPROS71_RS03990	COG2010	Cytochrome c
SynPROS71_RS04010	COG0659	secondary active sulfate transmembrane transporter activity
SynPROS71_RS04015	COG0418	dihydroorotase activity
SynPROS71_RS04055	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynPROS71_RS04055	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SynPROS71_RS04080	COG0159	tryptophan synthase activity
SynPROS71_RS04095	COG2010	Cytochrome c
SynPROS71_RS04125	COG3339	Conserved Protein
SynPROS71_RS04130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS04145	COG1376	ErfK ybiS ycfS ynhG family protein
SynPROS71_RS04150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynPROS71_RS04150	COG0140	phosphoribosyl-ATP diphosphatase activity
SynPROS71_RS04160	COG0542	response to heat
SynPROS71_RS04180	COG3794	PFAM blue (type 1) copper domain protein
SynPROS71_RS04190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynPROS71_RS04195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynPROS71_RS04235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynPROS71_RS04240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynPROS71_RS04270	COG0339	signal peptide processing
SynPROS71_RS04275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS04280	COG0083	homoserine kinase activity
SynPROS71_RS04285	COG0837	glucose binding
SynPROS71_RS04295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynPROS71_RS04315	COG0180	Tryptophanyl-tRNA synthetase
SynPROS71_RS04340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynPROS71_RS04355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynPROS71_RS04380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS04385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynPROS71_RS04415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynPROS71_RS04425	COG2226	methyltransferase
SynPROS71_RS04450	COG3781	membrane
SynPROS71_RS04470	COG1064	alcohol dehydrogenase
SynPROS71_RS04505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynPROS71_RS04655	COG0590	tRNA wobble adenosine to inosine editing
SynPROS71_RS04690	COG0484	heat shock protein binding
SynPROS71_RS04725	COG0405	Gamma-glutamyltransferase
SynPROS71_RS04745	COG3961	Belongs to the TPP enzyme family
SynPROS71_RS04755	COG1454	alcohol dehydrogenase
SynPROS71_RS04780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SynPROS71_RS04785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SynPROS71_RS04800	COG3895	Periplasmic Protein
SynPROS71_RS04830	COG0671	phosphoesterase, PA-phosphatase related
SynPROS71_RS04835	COG1487	ribonuclease activity
SynPROS71_RS04935	COG4067	protein conserved in archaea
SynPROS71_RS04935	COG0189	ligase activity
SynPROS71_RS04940	COG0346	lactoylglutathione lyase activity
SynPROS71_RS04945	COG0823	Involved in the tonB-independent uptake of proteins
SynPROS71_RS04945	COG1506	peptidase
SynPROS71_RS05005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SynPROS71_RS05155	COG0717	Belongs to the dCTP deaminase family
SynPROS71_RS05160	COG0300	oxidoreductase activity
SynPROS71_RS05280	COG0651	ATP synthesis coupled electron transport
SynPROS71_RS05285	COG1006	Multisubunit Na H antiporter MnhC subunit
SynPROS71_RS05295	COG3527	Alpha-acetolactate decarboxylase
SynPROS71_RS05300	COG0028	Belongs to the TPP enzyme family
SynPROS71_RS05345	COG1121	(ABC) transporter
SynPROS71_RS05350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynPROS71_RS05370	COG2010	Cytochrome c
SynPROS71_RS05375	COG0701	Predicted permease
SynPROS71_RS05390	COG1121	(ABC) transporter
SynPROS71_RS05395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynPROS71_RS05480	COG2124	cytochrome p450
SynPROS71_RS05550	COG2132	Multicopper oxidase
SynPROS71_RS05565	COG5002	protein histidine kinase activity
SynPROS71_RS05620	COG0681	Belongs to the peptidase S26 family
SynPROS71_RS05625	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynPROS71_RS05635	COG1376	ErfK ybiS ycfS ynhG family protein
SynPROS71_RS05640	COG0297	glycogen (starch) synthase activity
SynPROS71_RS05650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynPROS71_RS05660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynPROS71_RS05670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynPROS71_RS05675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynPROS71_RS05680	COG2045	Belongs to the ComB family
SynPROS71_RS05695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynPROS71_RS05700	COG0142	geranyltranstransferase activity
SynPROS71_RS05705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynPROS71_RS05710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynPROS71_RS05720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynPROS71_RS05725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SynPROS71_RS05735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynPROS71_RS05740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynPROS71_RS05755	COG2146	nitrite reductase [NAD(P)H] activity
SynPROS71_RS05770	COG0189	ligase activity
SynPROS71_RS05795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynPROS71_RS05805	COG1132	(ABC) transporter
SynPROS71_RS05815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynPROS71_RS05820	COG0505	Belongs to the CarA family
SynPROS71_RS05830	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynPROS71_RS05835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynPROS71_RS05845	COG0154	amidase activity
SynPROS71_RS05850	COG0587	DNA-directed DNA polymerase activity
SynPROS71_RS05860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynPROS71_RS05865	COG0632	four-way junction helicase activity
SynPROS71_RS05880	COG0358	DNA primase activity
SynPROS71_RS05890	COG0446	pyridine nucleotide-disulphide oxidoreductase
SynPROS71_RS05895	COG0798	PFAM Bile acid sodium symporter
SynPROS71_RS05925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynPROS71_RS05945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynPROS71_RS05950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynPROS71_RS05950	COG2308	Evidence 4 Homologs of previously reported genes of
SynPROS71_RS06005	COG2197	response regulator
SynPROS71_RS06080	COG0861	Integral membrane protein TerC family
SynPROS71_RS06100	COG0513	Belongs to the DEAD box helicase family
SynPROS71_RS06105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynPROS71_RS06115	COG0312	modulator of DNA gyrase
SynPROS71_RS06120	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynPROS71_RS06135	COG0163	prenyltransferase activity
SynPROS71_RS06140	COG0557	exoribonuclease II activity
SynPROS71_RS06150	COG2119	membrane
SynPROS71_RS06170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynPROS71_RS06170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynPROS71_RS06190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynPROS71_RS06195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynPROS71_RS06200	COG1615	UPF0182 protein
SynPROS71_RS06205	COG0450	alkyl hydroperoxide reductase
SynPROS71_RS06220	COG0739	heme binding
SynPROS71_RS06225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynPROS71_RS06260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynPROS71_RS06275	COG0129	dihydroxy-acid dehydratase activity
SynPROS71_RS06285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynPROS71_RS06300	COG2211	Major facilitator Superfamily
SynPROS71_RS06315	COG0300	oxidoreductase activity
SynPROS71_RS06325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynPROS71_RS06330	COG0047	phosphoribosylformylglycinamidine synthase activity
SynPROS71_RS06335	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynPROS71_RS06345	COG0191	fructose-bisphosphate aldolase activity
SynPROS71_RS06350	COG0673	inositol 2-dehydrogenase activity
SynPROS71_RS06360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynPROS71_RS06365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynPROS71_RS06375	COG3954	Phosphoribulokinase
SynPROS71_RS06380	COG0473	3-isopropylmalate dehydrogenase activity
SynPROS71_RS06385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynPROS71_RS06390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynPROS71_RS06405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynPROS71_RS06420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynPROS71_RS06425	COG2197	response regulator
SynPROS71_RS06435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynPROS71_RS06440	COG1090	epimerase
SynPROS71_RS06460	COG1376	ErfK ybiS ycfS ynhG family protein
SynPROS71_RS06485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynPROS71_RS06495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynPROS71_RS06510	COG3659	wide pore channel activity
SynPROS71_RS06515	COG1119	ATPase activity
SynPROS71_RS06525	COG0494	nUDIX hydrolase
SynPROS71_RS06560	COG1201	RNA secondary structure unwinding
SynPROS71_RS06580	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynPROS71_RS06590	COG1793	dna ligase
SynPROS71_RS06600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SynPROS71_RS06600	COG1793	dna ligase
SynPROS71_RS06635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynPROS71_RS06640	COG1175	transmembrane transport
SynPROS71_RS06645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynPROS71_RS06670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynPROS71_RS06690	COG0740	serine-type endopeptidase activity
SynPROS71_RS06700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynPROS71_RS06705	COG0577	efflux transmembrane transporter activity
SynPROS71_RS06705	COG1136	(ABC) transporter
SynPROS71_RS06710	COG0469	pyruvate kinase activity
SynPROS71_RS06730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynPROS71_RS06735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynPROS71_RS06760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynPROS71_RS06765	COG0598	Magnesium transport protein CorA
SynPROS71_RS06775	COG3842	ATPase activity
SynPROS71_RS06790	COG1653	transport
SynPROS71_RS06795	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynPROS71_RS06800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynPROS71_RS06805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynPROS71_RS06810	COG0326	Molecular chaperone. Has ATPase activity
SynPROS71_RS06820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynPROS71_RS06825	COG0483	inositol monophosphate 1-phosphatase activity
SynPROS71_RS06830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynPROS71_RS06840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynPROS71_RS06845	COG0581	inorganic phosphate transmembrane transporter activity
SynPROS71_RS06850	COG0573	inorganic phosphate transmembrane transporter activity
SynPROS71_RS06855	COG0443	Heat shock 70 kDa protein
SynPROS71_RS06860	COG0484	heat shock protein binding
SynPROS71_RS06870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynPROS71_RS06875	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynPROS71_RS06880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynPROS71_RS06885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynPROS71_RS06885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynPROS71_RS06890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynPROS71_RS06895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynPROS71_RS06920	COG0166	Belongs to the GPI family
SynPROS71_RS06925	COG0495	leucyl-tRNA aminoacylation
SynPROS71_RS06935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynPROS71_RS06940	COG1104	cysteine desulfurase activity
SynPROS71_RS06965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynPROS71_RS06970	COG0322	excinuclease ABC activity
SynPROS71_RS06980	COG3046	protein related to deoxyribodipyrimidine photolyase
SynPROS71_RS06985	COG1981	membrane
SynPROS71_RS07005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynPROS71_RS07010	COG1410	methionine synthase
SynPROS71_RS07010	COG0646	methionine synthase
SynPROS71_RS07035	COG2385	sporulation resulting in formation of a cellular spore
SynPROS71_RS07045	COG1191	sigma factor activity
SynPROS71_RS07070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynPROS71_RS07075	COG0072	phenylalanine-tRNA ligase activity
SynPROS71_RS07080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynPROS71_RS07085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynPROS71_RS07090	COG0557	exoribonuclease II activity
SynPROS71_RS07105	COG0363	glucosamine-6-phosphate deaminase activity
SynPROS71_RS07110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynPROS71_RS07115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynPROS71_RS07120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynPROS71_RS07125	COG1494	fructose-1,6-bisphosphatase
SynPROS71_RS07130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynPROS71_RS07135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynPROS71_RS07165	COG3220	belongs to the UPF0276 family
SynPROS71_RS07190	COG1217	gtp-binding protein TYPA
SynPROS71_RS07195	COG0826	peptidase U32
SynPROS71_RS07205	COG0644	oxidoreductase
SynPROS71_RS07210	COG0751	glycine-tRNA ligase activity
SynPROS71_RS07215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynPROS71_RS07220	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynPROS71_RS07225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynPROS71_RS07235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynPROS71_RS07240	COG0052	Belongs to the universal ribosomal protein uS2 family
SynPROS71_RS07245	COG1216	Glycosyl transferase, family 2
SynPROS71_RS07255	COG1136	(ABC) transporter
SynPROS71_RS07275	COG0612	Peptidase, M16
SynPROS71_RS07295	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynPROS71_RS07300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynPROS71_RS07320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynPROS71_RS07330	COG0174	glutamine synthetase
SynPROS71_RS07340	COG2226	methyltransferase
SynPROS71_RS07360	COG0515	serine threonine protein kinase
SynPROS71_RS07365	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynPROS71_RS07375	COG0628	permease
SynPROS71_RS07380	COG0628	permease
SynPROS71_RS07385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynPROS71_RS07385	COG0426	domain, Protein
SynPROS71_RS07395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynPROS71_RS07400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynPROS71_RS07405	COG0022	dehydrogenase e1 component
SynPROS71_RS07405	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynPROS71_RS07415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynPROS71_RS07420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynPROS71_RS07450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynPROS71_RS07465	COG0271	Belongs to the BolA IbaG family
SynPROS71_RS07470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynPROS71_RS07480	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS07505	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynPROS71_RS07525	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS07560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SynPROS71_RS07570	COG0735	belongs to the Fur family
SynPROS71_RS07580	COG1799	cell septum assembly
SynPROS71_RS07615	COG0420	3'-5' exonuclease activity
SynPROS71_RS07635	COG0477	Major facilitator Superfamily
SynPROS71_RS07645	COG2873	o-acetylhomoserine
SynPROS71_RS07650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynPROS71_RS07685	COG0765	amino acid transport
SynPROS71_RS07695	COG4597	amino acid ABC transporter
SynPROS71_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynPROS71_RS07710	COG0659	secondary active sulfate transmembrane transporter activity
SynPROS71_RS07750	COG0799	negative regulation of ribosome biogenesis
SynPROS71_RS07760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynPROS71_RS07770	COG1115	amino acid carrier protein
SynPROS71_RS07780	COG1132	(ABC) transporter
SynPROS71_RS07785	COG2501	S4 domain
SynPROS71_RS07790	COG0149	triose-phosphate isomerase activity
SynPROS71_RS07795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynPROS71_RS07805	COG1429	ligase activity, forming nitrogen-metal bonds
SynPROS71_RS07810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynPROS71_RS07820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS07825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynPROS71_RS07835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynPROS71_RS07910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynPROS71_RS07915	COG0640	Transcriptional regulator
SynPROS71_RS07960	COG3639	organic phosphonate transmembrane transporter activity
SynPROS71_RS07965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynPROS71_RS07965	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynPROS71_RS07970	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynPROS71_RS07975	COG0436	Aminotransferase
SynPROS71_RS07985	COG1573	uracil-dna glycosylase
SynPROS71_RS07990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynPROS71_RS07995	COG0793	Belongs to the peptidase S41A family
SynPROS71_RS08015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynPROS71_RS08035	COG1836	PFAM Integral membrane protein DUF92
SynPROS71_RS08060	COG1122	ATPase activity
SynPROS71_RS08065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynPROS71_RS08080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynPROS71_RS08085	COG4106	trans-aconitate 2-methyltransferase activity
SynPROS71_RS08090	COG0668	transmembrane transport
SynPROS71_RS08135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynPROS71_RS08140	COG1074	ATP-dependent DNA helicase activity
SynPROS71_RS08150	COG0662	Cupin 2, conserved barrel domain protein
SynPROS71_RS08150	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynPROS71_RS08155	COG0513	Belongs to the DEAD box helicase family
SynPROS71_RS08170	COG0724	RNA recognition motif
SynPROS71_RS08180	COG1132	(ABC) transporter
SynPROS71_RS08185	COG0589	response to stress
SynPROS71_RS08185	COG0475	glutathione-regulated potassium exporter activity
SynPROS71_RS08195	COG1404	Belongs to the peptidase S8 family
SynPROS71_RS08235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynPROS71_RS08240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynPROS71_RS08255	COG1054	Belongs to the UPF0176 family
SynPROS71_RS08260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynPROS71_RS08265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynPROS71_RS08270	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynPROS71_RS08275	COG0019	diaminopimelate decarboxylase activity
SynPROS71_RS08285	COG0542	response to heat
SynPROS71_RS08290	COG0371	Dehydrogenase
SynPROS71_RS08295	COG0596	Alpha beta hydrolase
SynPROS71_RS08295	COG2226	methyltransferase
SynPROS71_RS08295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SynPROS71_RS08305	COG0575	Belongs to the CDS family
SynPROS71_RS08310	COG1982	Orn Lys Arg decarboxylase major
SynPROS71_RS08320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynPROS71_RS08330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS08335	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS08340	COG5002	protein histidine kinase activity
SynPROS71_RS08345	COG1187	pseudouridine synthase activity
SynPROS71_RS08355	COG1640	4-alpha-glucanotransferase
SynPROS71_RS08360	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
SynPROS71_RS08375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynPROS71_RS08385	COG0308	aminopeptidase N
SynPROS71_RS08400	COG2205	protein histidine kinase activity
SynPROS71_RS08415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynPROS71_RS08420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynPROS71_RS08425	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynPROS71_RS08425	COG3409	Peptidoglycan-binding domain 1 protein
SynPROS71_RS08430	COG1797	cobyrinic acid a,c-diamide synthase activity
SynPROS71_RS08435	COG1254	Belongs to the acylphosphatase family
SynPROS71_RS08440	COG0406	alpha-ribazole phosphatase activity
SynPROS71_RS08460	COG0142	geranyltranstransferase activity
SynPROS71_RS08465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynPROS71_RS08470	COG1480	7TM receptor with intracellular HD hydrolase
SynPROS71_RS08475	COG0564	pseudouridine synthase activity
SynPROS71_RS08495	COG0011	TIGRFAM Protein of
SynPROS71_RS08515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynPROS71_RS08535	COG0395	ABC-type sugar transport system, permease component
SynPROS71_RS08540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynPROS71_RS08545	COG1543	Belongs to the glycosyl hydrolase 57 family
SynPROS71_RS08550	COG0644	oxidoreductase
SynPROS71_RS08555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynPROS71_RS08565	COG0516	GMP reductase activity
SynPROS71_RS08570	COG3118	belongs to the thioredoxin family
SynPROS71_RS08575	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynPROS71_RS08585	COG2010	Cytochrome c
SynPROS71_RS08605	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynPROS71_RS08610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynPROS71_RS08615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynPROS71_RS08630	COG2166	iron-sulfur cluster assembly
SynPROS71_RS08635	COG0460	homoserine dehydrogenase
SynPROS71_RS08650	COG0601	transmembrane transport
SynPROS71_RS08675	COG4095	Psort location CytoplasmicMembrane, score
SynPROS71_RS08685	COG0012	GTP binding
SynPROS71_RS08690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynPROS71_RS08695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynPROS71_RS08695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynPROS71_RS08700	COG0215	cysteine-tRNA ligase activity
SynPROS71_RS08715	COG0733	neurotransmitter:sodium symporter activity
SynPROS71_RS08720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynPROS71_RS08775	COG0492	ferredoxin-NADP+ reductase activity
SynPROS71_RS08780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynPROS71_RS08790	COG1187	pseudouridine synthase activity
SynPROS71_RS08795	COG2226	methyltransferase
SynPROS71_RS08805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynPROS71_RS08825	COG0440	acetolactate synthase activity
SynPROS71_RS08830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynPROS71_RS08870	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SynPROS71_RS08910	COG0424	maF-like protein
SynPROS71_RS08920	COG1492	cobalamin metabolic process
SynPROS71_RS08945	COG0432	Pfam Uncharacterised protein family UPF0047
SynPROS71_RS08950	COG0477	Major facilitator Superfamily
SynPROS71_RS08995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynPROS71_RS09015	COG0393	Putative heavy-metal-binding
SynPROS71_RS09030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynPROS71_RS09035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynPROS71_RS09055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynPROS71_RS09055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynPROS71_RS09175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynPROS71_RS09180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynPROS71_RS09185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynPROS71_RS09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynPROS71_RS09200	COG0196	riboflavin kinase activity
SynPROS71_RS09205	COG0352	thiamine-phosphate diphosphorylase activity
SynPROS71_RS09225	COG1691	(AIR) carboxylase
SynPROS71_RS09245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynPROS71_RS09255	COG0670	Belongs to the BI1 family
SynPROS71_RS09260	COG1702	phosphate starvation-inducible protein PhoH
SynPROS71_RS09265	COG0228	four-way junction DNA binding
SynPROS71_RS09270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynPROS71_RS09285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynPROS71_RS09290	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynPROS71_RS09295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS09300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynPROS71_RS09300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynPROS71_RS09305	COG0482	sulfurtransferase activity
SynPROS71_RS09310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynPROS71_RS09325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SynPROS71_RS09330	COG0134	indole-3-glycerol-phosphate synthase activity
SynPROS71_RS09335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynPROS71_RS09340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynPROS71_RS09355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynPROS71_RS09360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynPROS71_RS09365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynPROS71_RS09370	COG0285	dihydrofolate synthase activity
SynPROS71_RS09375	COG1357	PFAM Pentapeptide repeats (8 copies)
SynPROS71_RS09405	COG4948	Mandelate Racemase Muconate Lactonizing
SynPROS71_RS09410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynPROS71_RS09415	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynPROS71_RS09430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynPROS71_RS09440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynPROS71_RS09450	COG4956	integral membrane protein (PIN domain superfamily)
SynPROS71_RS09455	COG0740	serine-type endopeptidase activity
SynPROS71_RS09460	COG0740	serine-type endopeptidase activity
SynPROS71_RS09465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynPROS71_RS09470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynPROS71_RS09505	COG2217	Heavy metal translocating P-type atpase
SynPROS71_RS09550	COG0752	glycyl-tRNA synthetase alpha subunit
SynPROS71_RS09560	COG2226	methyltransferase
SynPROS71_RS09570	COG0107	imidazoleglycerol-phosphate synthase activity
SynPROS71_RS09580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynPROS71_RS09585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynPROS71_RS09590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynPROS71_RS09590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynPROS71_RS09605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynPROS71_RS09610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynPROS71_RS09625	COG5002	protein histidine kinase activity
SynPROS71_RS09635	COG2205	protein histidine kinase activity
SynPROS71_RS09660	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS09665	COG5002	protein histidine kinase activity
SynPROS71_RS09705	COG0481	GTPase activity
SynPROS71_RS09710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynPROS71_RS09720	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynPROS71_RS09725	COG0523	cobalamin synthesis protein
SynPROS71_RS09735	COG1840	ABC-type Fe3 transport system, periplasmic component
SynPROS71_RS09755	COG2271	Major facilitator Superfamily
SynPROS71_RS09765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynPROS71_RS09795	COG0277	FAD linked oxidase domain protein
SynPROS71_RS09800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynPROS71_RS09810	COG1666	GTP binding
SynPROS71_RS09825	COG0330	HflC and HflK could
SynPROS71_RS09840	COG0857	belongs to the CobB CobQ family
SynPROS71_RS09850	COG3000	fatty acid hydroxylase
SynPROS71_RS09850	COG0300	oxidoreductase activity
SynPROS71_RS09855	COG0024	Methionine aminopeptidase
SynPROS71_RS09865	COG0335	large ribosomal subunit rRNA binding
SynPROS71_RS09885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynPROS71_RS09890	COG3263	regulation of cellular component size
SynPROS71_RS09915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS09920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynPROS71_RS09935	COG0194	GDP metabolic process
SynPROS71_RS09940	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SynPROS71_RS09945	COG0805	protein transport
SynPROS71_RS09955	COG0723	plastoquinol--plastocyanin reductase activity
SynPROS71_RS09960	COG3258	Cytochrome c
SynPROS71_RS09965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynPROS71_RS09970	COG2875	Belongs to the precorrin methyltransferase family
SynPROS71_RS09985	COG0248	Ppx GppA phosphatase
SynPROS71_RS09990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynPROS71_RS09995	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynPROS71_RS10000	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynPROS71_RS10010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynPROS71_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
SynPROS71_RS10025	COG0459	protein refolding
SynPROS71_RS10035	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynPROS71_RS10055	COG0109	protoheme IX farnesyltransferase activity
SynPROS71_RS10060	COG1612	heme a metabolic process
SynPROS71_RS10075	COG1845	cytochrome c oxidase, subunit III
SynPROS71_RS10110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynPROS71_RS10125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynPROS71_RS10130	COG1007	ATP synthesis coupled electron transport
SynPROS71_RS10135	COG1136	(ABC) transporter
SynPROS71_RS10135	COG0577	efflux transmembrane transporter activity
SynPROS71_RS10140	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS10145	COG0739	heme binding
SynPROS71_RS10150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynPROS71_RS10150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynPROS71_RS10155	COG0436	Aminotransferase
SynPROS71_RS10160	COG3118	belongs to the thioredoxin family
SynPROS71_RS10165	COG1842	Phage shock protein A
SynPROS71_RS10175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynPROS71_RS10180	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS10185	COG0697	spore germination
SynPROS71_RS10190	COG0616	signal peptide processing
SynPROS71_RS10205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynPROS71_RS10210	COG0594	ribonuclease P activity
SynPROS71_RS10220	COG0706	membrane insertase activity
SynPROS71_RS10230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynPROS71_RS10240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynPROS71_RS10245	COG0750	zinc metalloprotease
SynPROS71_RS10250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynPROS71_RS10255	COG1185	polyribonucleotide nucleotidyltransferase activity
SynPROS71_RS10265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynPROS71_RS10405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynPROS71_RS10410	COG0776	regulation of translation
SynPROS71_RS10430	COG2211	Major facilitator Superfamily
SynPROS71_RS10435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynPROS71_RS10450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynPROS71_RS10485	COG0284	orotidine-5'-phosphate decarboxylase activity
SynPROS71_RS10505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynPROS71_RS10530	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynPROS71_RS10545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynPROS71_RS10555	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynPROS71_RS10560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynPROS71_RS10565	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynPROS71_RS10575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynPROS71_RS10585	COG0151	Belongs to the GarS family
SynPROS71_RS10590	COG5002	protein histidine kinase activity
SynPROS71_RS10595	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynPROS71_RS10600	COG4251	negative regulation of phosphorylation
SynPROS71_RS10610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynPROS71_RS10615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynPROS71_RS10630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynPROS71_RS10635	COG0217	transcriptional regulatory protein
SynPROS71_RS10645	COG0363	glucosamine-6-phosphate deaminase activity
SynPROS71_RS10650	COG2385	sporulation resulting in formation of a cellular spore
SynPROS71_RS10650	COG2247	cell wall binding repeat
SynPROS71_RS10655	COG1234	tRNA 3'-trailer cleavage
SynPROS71_RS10660	COG2010	Cytochrome c
SynPROS71_RS10675	COG2264	protein methyltransferase activity
SynPROS71_RS10680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynPROS71_RS10700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynPROS71_RS10735	COG0443	Heat shock 70 kDa protein
SynPROS71_RS10750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynPROS71_RS10755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynPROS71_RS10765	COG1970	mechanosensitive ion channel activity
SynPROS71_RS10770	COG0459	protein refolding
SynPROS71_RS10775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynPROS71_RS10780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynPROS71_RS10785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynPROS71_RS10800	COG0387	Pfam Sodium calcium exchanger
SynPROS71_RS10805	COG0006	proline dipeptidase activity
SynPROS71_RS10810	COG1253	flavin adenine dinucleotide binding
SynPROS71_RS10820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynPROS71_RS10825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynPROS71_RS10825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynPROS71_RS10835	COG3012	SEC-C Motif Domain Protein
SynPROS71_RS10840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynPROS71_RS10850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynPROS71_RS10860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynPROS71_RS10865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynPROS71_RS10870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynPROS71_RS10875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynPROS71_RS10880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynPROS71_RS10885	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynPROS71_RS10890	COG0356	it plays a direct role in the translocation of protons across the membrane
SynPROS71_RS10900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynPROS71_RS10905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynPROS71_RS10925	COG0772	Belongs to the SEDS family
SynPROS71_RS10935	COG1333	cytochrome c biogenesis protein
SynPROS71_RS10940	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynPROS71_RS10955	COG0347	Belongs to the P(II) protein family
SynPROS71_RS10960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SynPROS71_RS10970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynPROS71_RS10980	COG0114	fumarate hydratase activity
SynPROS71_RS10985	COG4581	dead DEAH box helicase
SynPROS71_RS10990	COG0385	Bile acid
SynPROS71_RS10995	COG0156	8-amino-7-oxononanoate synthase activity
SynPROS71_RS11010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynPROS71_RS11010	COG4106	trans-aconitate 2-methyltransferase activity
SynPROS71_RS11025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynPROS71_RS11040	COG0357	Ribosomal RNA small subunit methyltransferase G
SynPROS71_RS11075	COG2223	nitrite transmembrane transporter activity
SynPROS71_RS11080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynPROS71_RS11085	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS11090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynPROS71_RS11095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynPROS71_RS11100	COG0085	RNA polymerase activity
SynPROS71_RS11105	COG0084	hydrolase, TatD family'
SynPROS71_RS11110	COG0268	Binds directly to 16S ribosomal RNA
SynPROS71_RS11115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynPROS71_RS11120	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynPROS71_RS11125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynPROS71_RS11140	COG2197	response regulator
SynPROS71_RS11170	COG0641	radical SAM
SynPROS71_RS11180	COG0779	Required for maturation of 30S ribosomal subunits
SynPROS71_RS11185	COG0195	Participates in both transcription termination and antitermination
SynPROS71_RS11195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynPROS71_RS11240	COG2988	succinylglutamate desuccinylase activity
SynPROS71_RS11255	COG0488	(ABC) transporter
SynPROS71_RS11275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynPROS71_RS11280	COG3842	ATPase activity
SynPROS71_RS11285	COG1193	negative regulation of DNA recombination
SynPROS71_RS11295	COG0113	porphobilinogen synthase activity
SynPROS71_RS11300	COG0484	heat shock protein binding
SynPROS71_RS11310	COG0659	secondary active sulfate transmembrane transporter activity
SynPROS71_RS11335	COG0300	oxidoreductase activity
SynPROS71_RS11365	COG0116	Belongs to the methyltransferase superfamily
SynPROS71_RS11385	COG1196	nuclear chromosome segregation
SynPROS71_RS11395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynPROS71_RS11410	COG0439	Biotin carboxylase
SynPROS71_RS11425	COG0515	serine threonine protein kinase
SynPROS71_RS11445	COG4178	(ABC) transporter
SynPROS71_RS11450	COG0537	adenosine 5'-monophosphoramidase activity
SynPROS71_RS11455	COG0606	chelatase, subunit chli
SynPROS71_RS11460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynPROS71_RS11475	COG0242	peptide deformylase activity
SynPROS71_RS11490	COG0235	Class ii aldolase
SynPROS71_RS11495	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynPROS71_RS11510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynPROS71_RS11515	COG0719	Fe-S assembly protein
SynPROS71_RS11520	COG0396	ATPase activity
SynPROS71_RS11525	COG0719	Fe-S assembly protein
SynPROS71_RS11530	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynPROS71_RS11535	COG1830	Aldolase
SynPROS71_RS11555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynPROS71_RS11570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SynPROS71_RS11595	COG0033	Phosphoglucomutase
SynPROS71_RS11615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SynPROS71_RS11635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynPROS71_RS11640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynPROS71_RS11645	COG0175	sulfate reduction
SynPROS71_RS11650	COG1252	NADH dehydrogenase
SynPROS71_RS11655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynPROS71_RS11660	COG3273	potassium ion transport
SynPROS71_RS11660	COG0471	metal ion transport
SynPROS71_RS11665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynPROS71_RS11670	COG0569	domain protein
SynPROS71_RS11675	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynPROS71_RS11700	COG0488	(ABC) transporter
SynPROS71_RS11710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynPROS71_RS11725	COG1643	Atp-dependent helicase
SynPROS71_RS11730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynPROS71_RS11740	COG1570	exodeoxyribonuclease VII activity
SynPROS71_RS11745	COG1722	exodeoxyribonuclease VII activity
SynPROS71_RS11790	COG0483	inositol monophosphate 1-phosphatase activity
SynPROS71_RS11805	COG1968	undecaprenyl-diphosphatase activity
SynPROS71_RS11815	COG1555	photosystem II stabilization
SynPROS71_RS11820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynPROS71_RS11830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynPROS71_RS11845	COG1032	radical SAM domain protein
SynPROS71_RS11875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynPROS71_RS11900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynPROS71_RS11910	COG0463	Glycosyl transferase, family 2
SynPROS71_RS11910	COG0457	Tetratricopeptide repeat
SynPROS71_RS11915	COG1587	Uroporphyrinogen-III synthase
SynPROS71_RS11930	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynPROS71_RS11935	COG0316	Belongs to the HesB IscA family
SynPROS71_RS11955	COG1090	epimerase
SynPROS71_RS11975	COG0484	heat shock protein binding
SynPROS71_RS11980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynPROS71_RS11985	COG3659	wide pore channel activity
SynPROS71_RS11990	COG3659	wide pore channel activity
SynPROS71_RS12020	COG1122	ATPase activity
SynPROS71_RS12030	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS12040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynPROS71_RS12045	COG2217	Heavy metal translocating P-type atpase
SynPROS71_RS12050	COG3063	Type IV pilus biogenesis stability protein PilW
SynPROS71_RS12055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynPROS71_RS12065	COG0416	fatty acid biosynthetic process
SynPROS71_RS12070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynPROS71_RS12075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynPROS71_RS12090	COG1214	PFAM Peptidase M22, glycoprotease
SynPROS71_RS12100	COG0617	tRNA 3'-terminal CCA addition
SynPROS71_RS12165	COG1562	ergosterol biosynthetic process
SynPROS71_RS12170	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS12185	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynPROS71_RS12185	COG0493	'glutamate synthase
SynPROS71_RS12200	COG0583	DNA-binding transcription factor activity
SynPROS71_RS12210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynPROS71_RS12215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS12225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynPROS71_RS12235	COG2197	response regulator
SynPROS71_RS12250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynPROS71_RS12255	COG0713	ATP synthesis coupled electron transport
SynPROS71_RS12260	COG0839	Belongs to the complex I subunit 6 family
SynPROS71_RS12265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynPROS71_RS12270	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynPROS71_RS12275	COG0372	Belongs to the citrate synthase family
SynPROS71_RS12295	COG1420	regulation of RNA biosynthetic process
SynPROS71_RS12300	COG0133	tryptophan synthase activity
SynPROS71_RS12310	COG0023	Translation Initiation Factor
SynPROS71_RS12315	COG0529	Catalyzes the synthesis of activated sulfate
SynPROS71_RS12320	COG0628	permease
SynPROS71_RS12325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynPROS71_RS12335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynPROS71_RS12345	COG0564	pseudouridine synthase activity
SynPROS71_RS12350	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS12375	COG0275	rRNA processing
SynPROS71_RS12380	COG0649	NAD binding
SynPROS71_RS12385	COG0824	Thioesterase
SynPROS71_RS12400	COG1575	Belongs to the MenA family. Type 1 subfamily
SynPROS71_RS12415	COG0189	ligase activity
SynPROS71_RS12420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynPROS71_RS12445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynPROS71_RS12450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynPROS71_RS12455	COG0512	Glutamine amidotransferase of anthranilate synthase
SynPROS71_RS12465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynPROS71_RS12480	COG0252	asparaginase activity
SynPROS71_RS12490	COG0018	arginyl-trna synthetase
SynPROS71_RS12495	COG0157	Belongs to the NadC ModD family
SynPROS71_RS12505	COG0242	peptide deformylase activity
SynPROS71_RS12510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynPROS71_RS12525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynPROS71_RS12530	COG4172	Belongs to the ABC transporter superfamily
SynPROS71_RS12535	COG2909	trisaccharide binding
SynPROS71_RS12550	COG0564	pseudouridine synthase activity
SynPROS71_RS12555	COG2814	Major facilitator Superfamily
SynPROS71_RS12580	COG2124	cytochrome p450
SynPROS71_RS12590	COG0589	response to stress
SynPROS71_RS12595	COG0126	phosphoglycerate kinase activity
SynPROS71_RS12600	COG2084	Dehydrogenase
SynPROS71_RS12610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynPROS71_RS12615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynPROS71_RS12635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynPROS71_RS12645	COG1459	type II secretion system
SynPROS71_RS12670	COG0714	Associated with various cellular activities
SynPROS71_RS12695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SynPROS71_RS12695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SynPROS71_RS12710	COG1450	Type ii and iii secretion system protein
SynPROS71_RS12730	COG0167	dihydroorotate dehydrogenase activity
SynPROS71_RS12735	COG0328	RNA-DNA hybrid ribonuclease activity
SynPROS71_RS12745	COG0222	ribosome binding
SynPROS71_RS12750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynPROS71_RS12755	COG0081	regulation of translation
SynPROS71_RS12760	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynPROS71_RS12765	COG0250	Participates in transcription elongation, termination and antitermination
SynPROS71_RS12770	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynPROS71_RS12775	COG0542	response to heat
SynPROS71_RS12785	COG0148	phosphopyruvate hydratase activity
SynPROS71_RS12790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynPROS71_RS12845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynPROS71_RS12850	COG0237	dephospho-CoA kinase activity
SynPROS71_RS12875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynPROS71_RS12880	COG2022	thiamine diphosphate biosynthetic process
SynPROS71_RS12880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynPROS71_RS12890	COG0105	UTP biosynthetic process
SynPROS71_RS12895	COG1166	arginine decarboxylase activity
SynPROS71_RS12900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynPROS71_RS12960	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SynPROS71_RS13010	COG0668	transmembrane transport
SynPROS71_RS13020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynPROS71_RS13030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynPROS71_RS13055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynPROS71_RS13055	COG0426	domain, Protein
SynPROS71_RS13060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynPROS71_RS13060	COG0426	domain, Protein
SynPROS71_RS13075	COG1733	regulation of RNA biosynthetic process
SynPROS71_RS13090	COG1741	Belongs to the pirin family
SynPROS71_RS13115	COG0509	glycine decarboxylation via glycine cleavage system
SynPROS71_RS13120	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynPROS71_RS13140	COG0359	binds to the 23S rRNA
SynPROS71_RS13145	COG0305	Participates in initiation and elongation during chromosome replication
SynPROS71_RS13145	COG1372	Participates in initiation and elongation during chromosome replication
SynPROS71_RS13145	COG0305	Participates in initiation and elongation during chromosome replication
SynPROS71_RS13145	COG1372	Participates in initiation and elongation during chromosome replication
SynPROS71_RS13150	COG0445	tRNA wobble uridine modification
SynPROS71_RS13190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynPROS71_RS13205	COG0398	Pfam SNARE associated Golgi protein
SynPROS71_RS13230	COG0668	transmembrane transport
SynPROS71_RS13250	COG0745	RESPONSE REGULATOR receiver
SynPROS71_RS13255	COG0525	valine-tRNA ligase activity
SynPROS71_RS13265	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynPROS71_RS13265	COG3264	Mechanosensitive ion channel
SynPROS71_RS13305	COG3956	TIGRFAM MazG family protein
SynPROS71_RS13310	COG2272	Belongs to the type-B carboxylesterase lipase family
SynPROS71_RS13320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynPROS71_RS13335	COG0010	Belongs to the arginase family
SynPROS71_RS13350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynPROS71_RS13355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynPROS71_RS13360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS13365	COG0783	Belongs to the Dps family
SynPROS71_RS13370	COG0504	CTP synthase activity
SynPROS71_RS13375	COG0602	queuosine metabolic process
SynPROS71_RS13380	COG4942	peptidase
SynPROS71_RS13385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SynPROS71_RS13400	COG4574	serine-type endopeptidase inhibitor activity
SynPROS71_RS13405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynPROS71_RS13410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynPROS71_RS13420	COG0531	amino acid
SynPROS71_RS13435	COG0366	Alpha amylase catalytic
SynPROS71_RS13440	COG0463	Glycosyl transferase, family 2
SynPROS71_RS13475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynPROS71_RS13480	COG0830	nickel cation binding
SynPROS71_RS13485	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynPROS71_RS13490	COG0829	nickel cation binding
SynPROS71_RS13495	COG0831	urea catabolic process
SynPROS71_RS13500	COG0832	Belongs to the urease beta subunit family
SynPROS71_RS13505	COG0804	urea catabolic process
SynPROS71_RS13525	COG0367	asparagine synthase
SynPROS71_RS13530	COG0540	Belongs to the ATCase OTCase family
SynPROS71_RS13545	COG2308	Evidence 4 Homologs of previously reported genes of
SynPROS71_RS13565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynPROS71_RS13575	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynPROS71_RS13585	COG2116	formate transmembrane transporter activity
SynPROS71_RS13595	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynPROS71_RS13605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynPROS71_RS13620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynPROS71_RS13625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynPROS71_RS13630	COG0170	dolichyl monophosphate biosynthetic process
SynPROS71_RS13640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynPROS71_RS13645	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynPROS71_RS13665	COG0788	formyltetrahydrofolate deformylase activity
SynPROS71_RS13690	COG0443	Heat shock 70 kDa protein
SynPROS71_RS13695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynPROS71_RS13705	COG0360	Binds together with S18 to 16S ribosomal RNA
SynPROS71_RS13715	COG0137	argininosuccinate synthase activity
SynPROS71_RS13730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynPROS71_RS13750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynPROS71_RS13755	COG0438	transferase activity, transferring glycosyl groups
SynPROS71_RS13765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynPROS71_RS13770	COG0497	DNA recombination
SynPROS71_RS13775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynPROS71_RS13785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine