locus-tag	class	description
SynROS8604_RS00005	COG0592	DNA-directed DNA polymerase activity
SynROS8604_RS00015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynROS8604_RS00020	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SynROS8604_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynROS8604_RS00035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynROS8604_RS00050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynROS8604_RS00055	COG0552	protein localization to endoplasmic reticulum
SynROS8604_RS00060	COG2208	phosphoserine phosphatase activity
SynROS8604_RS00065	COG0165	Argininosuccinate lyase
SynROS8604_RS00070	COG0724	RNA recognition motif
SynROS8604_RS00075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynROS8604_RS00080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynROS8604_RS00085	COG2081	HI0933 family
SynROS8604_RS00090	COG1459	type II secretion system
SynROS8604_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynROS8604_RS00105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynROS8604_RS00110	COG0484	heat shock protein binding
SynROS8604_RS00120	COG1162	GTPase activity
SynROS8604_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynROS8604_RS00130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynROS8604_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynROS8604_RS00140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynROS8604_RS00145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynROS8604_RS00150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynROS8604_RS00155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynROS8604_RS00160	COG0511	ligase activity, forming carbon-carbon bonds
SynROS8604_RS00165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynROS8604_RS00235	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynROS8604_RS00240	COG0519	Catalyzes the synthesis of GMP from XMP
SynROS8604_RS00240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynROS8604_RS00255	COG0768	penicillin binding
SynROS8604_RS00260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynROS8604_RS00260	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS00265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynROS8604_RS00275	COG2022	thiamine diphosphate biosynthetic process
SynROS8604_RS00290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynROS8604_RS00295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynROS8604_RS00300	COG2385	sporulation resulting in formation of a cellular spore
SynROS8604_RS00305	COG1215	transferase activity, transferring glycosyl groups
SynROS8604_RS00310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynROS8604_RS00320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynROS8604_RS00325	COG0740	serine-type endopeptidase activity
SynROS8604_RS00330	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynROS8604_RS00335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynROS8604_RS00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynROS8604_RS00345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynROS8604_RS00355	COG0037	tRNA processing
SynROS8604_RS00370	COG0556	nucleotide-excision repair
SynROS8604_RS00385	COG2082	Precorrin-8x methylmutase
SynROS8604_RS00400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynROS8604_RS00435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynROS8604_RS00440	COG1088	dTDP-glucose 4,6-dehydratase activity
SynROS8604_RS00450	COG1215	transferase activity, transferring glycosyl groups
SynROS8604_RS00455	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS00515	COG2274	protein secretion by the type I secretion system
SynROS8604_RS00525	COG0653	protein targeting
SynROS8604_RS00535	COG1045	serine acetyltransferase
SynROS8604_RS00540	COG1725	Transcriptional regulator
SynROS8604_RS00550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynROS8604_RS00555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynROS8604_RS00560	COG1372	Participates in initiation and elongation during chromosome replication
SynROS8604_RS00560	COG0187	DNA topoisomerase II activity
SynROS8604_RS00570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynROS8604_RS00575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynROS8604_RS00580	COG0386	Belongs to the glutathione peroxidase family
SynROS8604_RS00585	COG2239	Acts as a magnesium transporter
SynROS8604_RS00590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS00605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynROS8604_RS00630	COG1819	glycosyl
SynROS8604_RS00660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynROS8604_RS00665	COG0242	peptide deformylase activity
SynROS8604_RS00670	COG2308	Evidence 4 Homologs of previously reported genes of
SynROS8604_RS00680	COG0189	ligase activity
SynROS8604_RS00685	COG0697	spore germination
SynROS8604_RS00715	COG0174	glutamine synthetase
SynROS8604_RS00725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SynROS8604_RS00730	COG0802	atpase or kinase
SynROS8604_RS00735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynROS8604_RS00740	COG0586	Pfam SNARE associated Golgi protein
SynROS8604_RS00745	COG0629	single-stranded DNA binding
SynROS8604_RS00775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynROS8604_RS00795	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynROS8604_RS00800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynROS8604_RS00805	COG0515	serine threonine protein kinase
SynROS8604_RS00805	COG1357	PFAM Pentapeptide repeats (8 copies)
SynROS8604_RS00810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynROS8604_RS00815	COG2255	four-way junction helicase activity
SynROS8604_RS00825	COG1473	amidohydrolase
SynROS8604_RS00840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynROS8604_RS00860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynROS8604_RS00865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynROS8604_RS00870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynROS8604_RS00875	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS00880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynROS8604_RS00920	COG2274	protein secretion by the type I secretion system
SynROS8604_RS00980	COG1215	transferase activity, transferring glycosyl groups
SynROS8604_RS01115	COG0297	glycogen (starch) synthase activity
SynROS8604_RS01130	COG0489	protein tyrosine kinase activity
SynROS8604_RS01170	COG0297	glycogen (starch) synthase activity
SynROS8604_RS01200	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynROS8604_RS01205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynROS8604_RS01220	COG1132	(ABC) transporter
SynROS8604_RS01235	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS01250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynROS8604_RS01265	COG0297	glycogen (starch) synthase activity
SynROS8604_RS01270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynROS8604_RS01285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynROS8604_RS01290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynROS8604_RS01300	COG0110	maltose O-acetyltransferase activity
SynROS8604_RS01310	COG0297	glycogen (starch) synthase activity
SynROS8604_RS01320	COG0494	nUDIX hydrolase
SynROS8604_RS01390	COG1487	ribonuclease activity
SynROS8604_RS01400	COG4118	positive regulation of growth
SynROS8604_RS01440	COG0471	metal ion transport
SynROS8604_RS01440	COG3273	potassium ion transport
SynROS8604_RS01445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynROS8604_RS01455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynROS8604_RS01470	COG0571	ribonuclease III activity
SynROS8604_RS01510	COG0058	SHG alpha-glucan phosphorylase activity
SynROS8604_RS01515	COG0475	glutathione-regulated potassium exporter activity
SynROS8604_RS01535	COG0277	FAD linked oxidase domain protein
SynROS8604_RS01545	COG0247	lactate metabolic process
SynROS8604_RS01550	COG0538	isocitrate dehydrogenase activity
SynROS8604_RS01555	COG0463	Glycosyl transferase, family 2
SynROS8604_RS01570	COG5398	heme oxygenase
SynROS8604_RS01580	COG1132	(ABC) transporter
SynROS8604_RS01585	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS01590	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS01595	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS01600	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS01620	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynROS8604_RS01630	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SynROS8604_RS01640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynROS8604_RS01665	COG0617	tRNA 3'-terminal CCA addition
SynROS8604_RS01675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynROS8604_RS01680	COG0124	histidyl-tRNA synthetase
SynROS8604_RS01685	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SynROS8604_RS01720	COG4447	cellulose binding
SynROS8604_RS01725	COG1773	rubredoxin
SynROS8604_RS01730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS01735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS01740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS01745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynROS8604_RS01750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynROS8604_RS01755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SynROS8604_RS01760	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynROS8604_RS01760	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynROS8604_RS01765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SynROS8604_RS01815	COG1132	(ABC) transporter
SynROS8604_RS01845	COG0494	nUDIX hydrolase
SynROS8604_RS01850	COG0415	Belongs to the DNA photolyase family
SynROS8604_RS01880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynROS8604_RS01885	COG3781	membrane
SynROS8604_RS01890	COG0131	Imidazoleglycerol-phosphate dehydratase
SynROS8604_RS01895	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynROS8604_RS01910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynROS8604_RS01930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynROS8604_RS01935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynROS8604_RS01945	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynROS8604_RS01950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynROS8604_RS01965	COG1253	flavin adenine dinucleotide binding
SynROS8604_RS01970	COG0673	inositol 2-dehydrogenase activity
SynROS8604_RS02025	COG0343	queuine tRNA-ribosyltransferase activity
SynROS8604_RS02055	COG0138	bifunctional purine biosynthesis protein purh
SynROS8604_RS02070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynROS8604_RS02075	COG0004	ammonium transporteR
SynROS8604_RS02080	COG1489	DNA binding
SynROS8604_RS02085	COG0728	peptidoglycan biosynthetic process
SynROS8604_RS02110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynROS8604_RS02115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynROS8604_RS02120	COG1058	Belongs to the CinA family
SynROS8604_RS02120	COG1546	Belongs to the CinA family
SynROS8604_RS02125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynROS8604_RS02130	COG0066	3-isopropylmalate dehydratase activity
SynROS8604_RS02165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynROS8604_RS02170	COG0193	aminoacyl-tRNA hydrolase activity
SynROS8604_RS02185	COG4372	Transposase
SynROS8604_RS02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynROS8604_RS02195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynROS8604_RS02205	COG0717	Belongs to the dCTP deaminase family
SynROS8604_RS02215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynROS8604_RS02235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynROS8604_RS02250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynROS8604_RS02270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynROS8604_RS02290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynROS8604_RS02305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynROS8604_RS02320	COG2094	Belongs to the DNA glycosylase MPG family
SynROS8604_RS02325	COG0540	Belongs to the ATCase OTCase family
SynROS8604_RS02360	COG3536	Protein conserved in bacteria
SynROS8604_RS02365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynROS8604_RS02375	COG0529	Catalyzes the synthesis of activated sulfate
SynROS8604_RS02375	COG2046	Belongs to the sulfate adenylyltransferase family
SynROS8604_RS02380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynROS8604_RS02395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynROS8604_RS02405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynROS8604_RS02410	COG2226	methyltransferase
SynROS8604_RS02420	COG4176	ABC-type proline glycine betaine transport system permease component
SynROS8604_RS02425	COG2113	Glycine betaine
SynROS8604_RS02430	COG0463	Glycosyl transferase, family 2
SynROS8604_RS02435	COG0366	Alpha amylase catalytic
SynROS8604_RS02490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynROS8604_RS02500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynROS8604_RS02505	COG0436	Aminotransferase
SynROS8604_RS02515	COG1530	ribonuclease E activity
SynROS8604_RS02520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynROS8604_RS02530	COG0077	Prephenate dehydratase
SynROS8604_RS02530	COG1605	Chorismate mutase
SynROS8604_RS02535	COG2226	methyltransferase
SynROS8604_RS02545	COG0051	transcription antitermination factor activity, RNA binding
SynROS8604_RS02550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynROS8604_RS02555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynROS8604_RS02560	COG0049	tRNA binding
SynROS8604_RS02565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynROS8604_RS02580	COG0067	glutamate synthase
SynROS8604_RS02580	COG0070	glutamate synthase
SynROS8604_RS02580	COG0069	glutamate synthase activity
SynROS8604_RS02590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynROS8604_RS02610	COG2885	chlorophyll binding
SynROS8604_RS02615	COG2885	chlorophyll binding
SynROS8604_RS02625	COG3239	Fatty acid desaturase
SynROS8604_RS02650	COG0463	Glycosyl transferase, family 2
SynROS8604_RS02670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynROS8604_RS02680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynROS8604_RS02685	COG0254	rRNA binding
SynROS8604_RS02690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynROS8604_RS02695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynROS8604_RS02700	COG0101	tRNA pseudouridine synthase activity
SynROS8604_RS02705	COG0203	ribosomal protein L17
SynROS8604_RS02710	COG0202	RNA polymerase activity
SynROS8604_RS02715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynROS8604_RS02720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynROS8604_RS02725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SynROS8604_RS02730	COG0563	adenylate kinase activity
SynROS8604_RS02735	COG0201	protein transport
SynROS8604_RS02740	COG0200	Binds to the 23S rRNA
SynROS8604_RS02745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynROS8604_RS02750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynROS8604_RS02755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynROS8604_RS02760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynROS8604_RS02765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynROS8604_RS02770	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynROS8604_RS02775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynROS8604_RS02780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynROS8604_RS02785	COG0255	Belongs to the universal ribosomal protein uL29 family
SynROS8604_RS02790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynROS8604_RS02795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynROS8604_RS02800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynROS8604_RS02805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynROS8604_RS02810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynROS8604_RS02815	COG0089	rRNA binding
SynROS8604_RS02820	COG0088	Forms part of the polypeptide exit tunnel
SynROS8604_RS02825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynROS8604_RS02840	COG3854	ATPases associated with a variety of cellular activities
SynROS8604_RS02855	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynROS8604_RS02875	COG0287	Prephenate dehydrogenase
SynROS8604_RS02885	COG3001	Fructosamine kinase
SynROS8604_RS02905	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynROS8604_RS02910	COG1606	tRNA processing
SynROS8604_RS02915	COG0076	glutamate decarboxylase activity
SynROS8604_RS02920	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynROS8604_RS02925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynROS8604_RS02940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynROS8604_RS02950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynROS8604_RS02960	COG5002	protein histidine kinase activity
SynROS8604_RS02965	COG0772	Belongs to the SEDS family
SynROS8604_RS02970	COG0489	protein tyrosine kinase activity
SynROS8604_RS02975	COG0408	coproporphyrinogen oxidase activity
SynROS8604_RS03060	COG0667	Aldo Keto reductase
SynROS8604_RS03070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynROS8604_RS03075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynROS8604_RS03080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynROS8604_RS03080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynROS8604_RS03085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynROS8604_RS03230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynROS8604_RS03285	COG1070	Carbohydrate kinase
SynROS8604_RS03290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynROS8604_RS03300	COG0539	negative regulation of cytoplasmic translation
SynROS8604_RS03305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynROS8604_RS03330	COG0589	response to stress
SynROS8604_RS03340	COG0758	DNA mediated transformation
SynROS8604_RS03345	COG2890	protein-(glutamine-N5) methyltransferase activity
SynROS8604_RS03350	COG0009	L-threonylcarbamoyladenylate synthase
SynROS8604_RS03370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynROS8604_RS03375	COG2894	cell division
SynROS8604_RS03380	COG0850	regulation of cytokinetic process
SynROS8604_RS03385	COG1078	dGTPase activity
SynROS8604_RS03390	COG0793	Belongs to the peptidase S41A family
SynROS8604_RS03395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynROS8604_RS03400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynROS8604_RS03435	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynROS8604_RS03450	COG0514	ATP-dependent DNA helicase (RecQ)
SynROS8604_RS03455	COG3942	CHAP domain
SynROS8604_RS03455	COG1388	LysM domain
SynROS8604_RS03470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynROS8604_RS03500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynROS8604_RS03515	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynROS8604_RS03545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynROS8604_RS03555	COG1376	ErfK ybiS ycfS ynhG family protein
SynROS8604_RS03560	COG1160	GTP binding
SynROS8604_RS03565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynROS8604_RS03575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynROS8604_RS03580	COG1799	cell septum assembly
SynROS8604_RS03585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynROS8604_RS03590	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS03600	COG1381	Involved in DNA repair and RecF pathway recombination
SynROS8604_RS03605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynROS8604_RS03610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynROS8604_RS03615	COG0321	lipoyl(octanoyl) transferase activity
SynROS8604_RS03620	COG1022	Amp-dependent synthetase and ligase
SynROS8604_RS03630	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynROS8604_RS03635	COG0531	amino acid
SynROS8604_RS03640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynROS8604_RS03710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynROS8604_RS03720	COG0626	cystathionine gamma-synthase activity
SynROS8604_RS03740	COG4178	(ABC) transporter
SynROS8604_RS03760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SynROS8604_RS03775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SynROS8604_RS03785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynROS8604_RS03805	COG1104	cysteine desulfurase activity
SynROS8604_RS03825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynROS8604_RS03830	COG0579	oxidoreductase
SynROS8604_RS03840	COG0481	GTPase activity
SynROS8604_RS03885	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS03920	COG5002	protein histidine kinase activity
SynROS8604_RS03935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynROS8604_RS03950	COG3695	enzyme binding
SynROS8604_RS03955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynROS8604_RS03955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynROS8604_RS03960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynROS8604_RS03965	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynROS8604_RS03975	COG0107	imidazoleglycerol-phosphate synthase activity
SynROS8604_RS03985	COG2226	methyltransferase
SynROS8604_RS04005	COG0752	glycyl-tRNA synthetase alpha subunit
SynROS8604_RS04090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynROS8604_RS04095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynROS8604_RS04105	COG0740	serine-type endopeptidase activity
SynROS8604_RS04110	COG0740	serine-type endopeptidase activity
SynROS8604_RS04115	COG4956	integral membrane protein (PIN domain superfamily)
SynROS8604_RS04120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynROS8604_RS04125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynROS8604_RS04135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynROS8604_RS04150	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynROS8604_RS04155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynROS8604_RS04160	COG4948	Mandelate Racemase Muconate Lactonizing
SynROS8604_RS04190	COG1357	PFAM Pentapeptide repeats (8 copies)
SynROS8604_RS04195	COG0285	dihydrofolate synthase activity
SynROS8604_RS04200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynROS8604_RS04210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynROS8604_RS04225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynROS8604_RS04230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynROS8604_RS04235	COG0134	indole-3-glycerol-phosphate synthase activity
SynROS8604_RS04265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynROS8604_RS04270	COG0482	sulfurtransferase activity
SynROS8604_RS04275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynROS8604_RS04275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynROS8604_RS04280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS04345	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynROS8604_RS04350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynROS8604_RS04360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynROS8604_RS04365	COG0228	four-way junction DNA binding
SynROS8604_RS04370	COG1702	phosphate starvation-inducible protein PhoH
SynROS8604_RS04395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynROS8604_RS04405	COG0336	Belongs to the RNA methyltransferase TrmD family
SynROS8604_RS04450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynROS8604_RS04460	COG1691	(AIR) carboxylase
SynROS8604_RS04480	COG0352	thiamine-phosphate diphosphorylase activity
SynROS8604_RS04485	COG0196	riboflavin kinase activity
SynROS8604_RS04495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynROS8604_RS04500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynROS8604_RS04515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynROS8604_RS04525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynROS8604_RS04635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynROS8604_RS04650	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SynROS8604_RS04665	COG1715	Restriction endonuclease
SynROS8604_RS04745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynROS8604_RS04755	COG1803	Methylglyoxal synthase
SynROS8604_RS04755	COG1597	lipid kinase activity
SynROS8604_RS04780	COG3119	arylsulfatase activity
SynROS8604_RS04875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynROS8604_RS04875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynROS8604_RS04890	COG1803	Methylglyoxal synthase
SynROS8604_RS04910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynROS8604_RS04915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynROS8604_RS04940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynROS8604_RS05080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynROS8604_RS05110	COG1942	4-Oxalocrotonate Tautomerase
SynROS8604_RS05155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynROS8604_RS05180	COG0477	Major facilitator Superfamily
SynROS8604_RS05200	COG0432	Pfam Uncharacterised protein family UPF0047
SynROS8604_RS05220	COG1492	cobalamin metabolic process
SynROS8604_RS05240	COG0424	maF-like protein
SynROS8604_RS05265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynROS8604_RS05270	COG0440	acetolactate synthase activity
SynROS8604_RS05275	COG2267	carboxylic ester hydrolase activity
SynROS8604_RS05305	COG1187	pseudouridine synthase activity
SynROS8604_RS05315	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynROS8604_RS05320	COG0492	ferredoxin-NADP+ reductase activity
SynROS8604_RS05365	COG3411	Ferredoxin
SynROS8604_RS05370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynROS8604_RS05375	COG0733	neurotransmitter:sodium symporter activity
SynROS8604_RS05390	COG0215	cysteine-tRNA ligase activity
SynROS8604_RS05400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynROS8604_RS05400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynROS8604_RS05405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynROS8604_RS05410	COG0012	GTP binding
SynROS8604_RS05455	COG0601	transmembrane transport
SynROS8604_RS05460	COG4166	transmembrane transport
SynROS8604_RS05470	COG0460	homoserine dehydrogenase
SynROS8604_RS05475	COG2166	iron-sulfur cluster assembly
SynROS8604_RS05485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SynROS8604_RS05495	COG0288	reversible hydration of carbon dioxide
SynROS8604_RS05535	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynROS8604_RS05540	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynROS8604_RS05555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SynROS8604_RS05560	COG2010	Cytochrome c
SynROS8604_RS05570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynROS8604_RS05575	COG3118	belongs to the thioredoxin family
SynROS8604_RS05580	COG0516	GMP reductase activity
SynROS8604_RS05590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynROS8604_RS05595	COG0644	oxidoreductase
SynROS8604_RS05600	COG1543	Belongs to the glycosyl hydrolase 57 family
SynROS8604_RS05605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynROS8604_RS05610	COG0395	ABC-type sugar transport system, permease component
SynROS8604_RS05625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynROS8604_RS05670	COG1480	7TM receptor with intracellular HD hydrolase
SynROS8604_RS05675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynROS8604_RS05680	COG0142	geranyltranstransferase activity
SynROS8604_RS05725	COG0406	alpha-ribazole phosphatase activity
SynROS8604_RS05730	COG1254	Belongs to the acylphosphatase family
SynROS8604_RS05735	COG1797	cobyrinic acid a,c-diamide synthase activity
SynROS8604_RS05740	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynROS8604_RS05740	COG3409	Peptidoglycan-binding domain 1 protein
SynROS8604_RS05745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynROS8604_RS05770	COG2205	protein histidine kinase activity
SynROS8604_RS05785	COG0308	aminopeptidase N
SynROS8604_RS05795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynROS8604_RS05815	COG1640	4-alpha-glucanotransferase
SynROS8604_RS05825	COG1187	pseudouridine synthase activity
SynROS8604_RS05830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS05840	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynROS8604_RS05845	COG1982	Orn Lys Arg decarboxylase major
SynROS8604_RS05850	COG0575	Belongs to the CDS family
SynROS8604_RS05860	COG2267	carboxylic ester hydrolase activity
SynROS8604_RS05865	COG0371	Dehydrogenase
SynROS8604_RS05870	COG0542	response to heat
SynROS8604_RS05875	COG0456	acetyltransferase
SynROS8604_RS05880	COG0019	diaminopimelate decarboxylase activity
SynROS8604_RS05885	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynROS8604_RS05890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynROS8604_RS05895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynROS8604_RS05900	COG1054	Belongs to the UPF0176 family
SynROS8604_RS05915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynROS8604_RS05920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynROS8604_RS05955	COG0589	response to stress
SynROS8604_RS05955	COG0475	glutathione-regulated potassium exporter activity
SynROS8604_RS05960	COG1132	(ABC) transporter
SynROS8604_RS05970	COG0724	RNA recognition motif
SynROS8604_RS05980	COG0513	Belongs to the DEAD box helicase family
SynROS8604_RS05985	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynROS8604_RS05985	COG0662	Cupin 2, conserved barrel domain protein
SynROS8604_RS05990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynROS8604_RS05995	COG1074	ATP-dependent DNA helicase activity
SynROS8604_RS06000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynROS8604_RS06030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS06125	COG2205	protein histidine kinase activity
SynROS8604_RS06130	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS06140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SynROS8604_RS06150	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynROS8604_RS06175	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS06185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynROS8604_RS06190	COG0271	Belongs to the BolA IbaG family
SynROS8604_RS06205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynROS8604_RS06220	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SynROS8604_RS06235	COG0625	glutathione transferase activity
SynROS8604_RS06265	COG0735	belongs to the Fur family
SynROS8604_RS06275	COG1799	cell septum assembly
SynROS8604_RS06290	COG0625	glutathione transferase activity
SynROS8604_RS06305	COG0420	3'-5' exonuclease activity
SynROS8604_RS06335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynROS8604_RS06360	COG1126	abc transporter atp-binding protein
SynROS8604_RS06365	COG0765	amino acid transport
SynROS8604_RS06375	COG4597	amino acid ABC transporter
SynROS8604_RS06380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynROS8604_RS06390	COG0659	secondary active sulfate transmembrane transporter activity
SynROS8604_RS06430	COG0799	negative regulation of ribosome biogenesis
SynROS8604_RS06440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynROS8604_RS06450	COG1115	amino acid carrier protein
SynROS8604_RS06460	COG1132	(ABC) transporter
SynROS8604_RS06470	COG0149	triose-phosphate isomerase activity
SynROS8604_RS06475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynROS8604_RS06485	COG1429	ligase activity, forming nitrogen-metal bonds
SynROS8604_RS06490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynROS8604_RS06500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS06505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynROS8604_RS06515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynROS8604_RS06610	COG0393	Putative heavy-metal-binding
SynROS8604_RS06645	COG0668	transmembrane transport
SynROS8604_RS06650	COG4106	trans-aconitate 2-methyltransferase activity
SynROS8604_RS06655	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynROS8604_RS06670	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynROS8604_RS06675	COG1122	ATPase activity
SynROS8604_RS06685	COG0052	Belongs to the universal ribosomal protein uS2 family
SynROS8604_RS06690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynROS8604_RS06700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynROS8604_RS06705	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynROS8604_RS06710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynROS8604_RS06715	COG0751	glycine-tRNA ligase activity
SynROS8604_RS06720	COG0644	oxidoreductase
SynROS8604_RS06730	COG0826	peptidase U32
SynROS8604_RS06735	COG1217	gtp-binding protein TYPA
SynROS8604_RS06760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynROS8604_RS06780	COG0443	Heat shock 70 kDa protein
SynROS8604_RS06790	COG0861	Integral membrane protein TerC family
SynROS8604_RS06810	COG0513	Belongs to the DEAD box helicase family
SynROS8604_RS06815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynROS8604_RS06825	COG0312	modulator of DNA gyrase
SynROS8604_RS06830	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynROS8604_RS06845	COG0163	prenyltransferase activity
SynROS8604_RS06850	COG0557	exoribonuclease II activity
SynROS8604_RS06860	COG2119	membrane
SynROS8604_RS06880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynROS8604_RS06880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynROS8604_RS06900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynROS8604_RS06905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynROS8604_RS06910	COG1615	UPF0182 protein
SynROS8604_RS06920	COG0450	alkyl hydroperoxide reductase
SynROS8604_RS06935	COG0739	heme binding
SynROS8604_RS06940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynROS8604_RS07005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynROS8604_RS07020	COG0557	exoribonuclease II activity
SynROS8604_RS07025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynROS8604_RS07030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynROS8604_RS07035	COG0072	phenylalanine-tRNA ligase activity
SynROS8604_RS07035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynROS8604_RS07040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynROS8604_RS07070	COG2385	sporulation resulting in formation of a cellular spore
SynROS8604_RS07095	COG0646	methionine synthase
SynROS8604_RS07095	COG1410	methionine synthase
SynROS8604_RS07100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynROS8604_RS07115	COG0613	PHP domain protein
SynROS8604_RS07120	COG1981	membrane
SynROS8604_RS07125	COG3046	protein related to deoxyribodipyrimidine photolyase
SynROS8604_RS07135	COG0322	excinuclease ABC activity
SynROS8604_RS07140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynROS8604_RS07165	COG1104	cysteine desulfurase activity
SynROS8604_RS07170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynROS8604_RS07180	COG0495	leucyl-tRNA aminoacylation
SynROS8604_RS07185	COG0166	Belongs to the GPI family
SynROS8604_RS07210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynROS8604_RS07215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynROS8604_RS07220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynROS8604_RS07220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynROS8604_RS07225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynROS8604_RS07230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynROS8604_RS07235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynROS8604_RS07245	COG0484	heat shock protein binding
SynROS8604_RS07250	COG0443	Heat shock 70 kDa protein
SynROS8604_RS07255	COG0573	inorganic phosphate transmembrane transporter activity
SynROS8604_RS07260	COG0581	inorganic phosphate transmembrane transporter activity
SynROS8604_RS07265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynROS8604_RS07285	COG0483	inositol monophosphate 1-phosphatase activity
SynROS8604_RS07290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynROS8604_RS07300	COG0326	Molecular chaperone. Has ATPase activity
SynROS8604_RS07305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynROS8604_RS07310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynROS8604_RS07315	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynROS8604_RS07320	COG1653	transport
SynROS8604_RS07360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynROS8604_RS07365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynROS8604_RS07385	COG0469	pyruvate kinase activity
SynROS8604_RS07390	COG1136	(ABC) transporter
SynROS8604_RS07390	COG0577	efflux transmembrane transporter activity
SynROS8604_RS07395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynROS8604_RS07400	COG0740	serine-type endopeptidase activity
SynROS8604_RS07425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynROS8604_RS07430	COG2211	Major facilitator Superfamily
SynROS8604_RS07455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynROS8604_RS07460	COG1175	transmembrane transport
SynROS8604_RS07465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynROS8604_RS07500	COG1793	dna ligase
SynROS8604_RS07500	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SynROS8604_RS07510	COG1201	RNA secondary structure unwinding
SynROS8604_RS07565	COG0484	heat shock protein binding
SynROS8604_RS07580	COG1121	(ABC) transporter
SynROS8604_RS07585	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynROS8604_RS07590	COG3659	wide pore channel activity
SynROS8604_RS07610	COG2124	cytochrome p450
SynROS8604_RS07615	COG2226	methyltransferase
SynROS8604_RS07640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SynROS8604_RS07650	COG2124	cytochrome p450
SynROS8604_RS07670	COG2124	cytochrome p450
SynROS8604_RS07685	COG1454	alcohol dehydrogenase
SynROS8604_RS07690	COG0405	Gamma-glutamyltransferase
SynROS8604_RS07820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SynROS8604_RS07825	COG1611	Belongs to the LOG family
SynROS8604_RS07835	COG2197	response regulator
SynROS8604_RS07895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SynROS8604_RS07985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SynROS8604_RS07990	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SynROS8604_RS08090	COG3961	Belongs to the TPP enzyme family
SynROS8604_RS08130	COG0523	cobalamin synthesis protein
SynROS8604_RS08225	COG2144	transferase activity, transferring acyl groups
SynROS8604_RS08275	COG2132	Multicopper oxidase
SynROS8604_RS08290	COG5002	protein histidine kinase activity
SynROS8604_RS08330	COG0681	Belongs to the peptidase S26 family
SynROS8604_RS08335	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynROS8604_RS08345	COG1376	ErfK ybiS ycfS ynhG family protein
SynROS8604_RS08350	COG0297	glycogen (starch) synthase activity
SynROS8604_RS08360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynROS8604_RS08370	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynROS8604_RS08385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynROS8604_RS08385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SynROS8604_RS08390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynROS8604_RS08405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynROS8604_RS08410	COG3659	wide pore channel activity
SynROS8604_RS08420	COG3128	pkhd-type hydroxylase
SynROS8604_RS08425	COG1840	ABC-type Fe3 transport system, periplasmic component
SynROS8604_RS08430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynROS8604_RS08435	COG2045	Belongs to the ComB family
SynROS8604_RS08445	COG0860	N-Acetylmuramoyl-L-alanine amidase
SynROS8604_RS08450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynROS8604_RS08455	COG0142	geranyltranstransferase activity
SynROS8604_RS08460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynROS8604_RS08465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynROS8604_RS08480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynROS8604_RS08485	COG2176	DNA-directed DNA polymerase activity
SynROS8604_RS08495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynROS8604_RS08505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynROS8604_RS08510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynROS8604_RS08515	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS08520	COG3659	wide pore channel activity
SynROS8604_RS08535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynROS8604_RS08540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynROS8604_RS08560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynROS8604_RS08570	COG0174	glutamine synthetase
SynROS8604_RS08605	COG2226	methyltransferase
SynROS8604_RS08630	COG0515	serine threonine protein kinase
SynROS8604_RS08635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynROS8604_RS08645	COG1012	belongs to the aldehyde dehydrogenase family
SynROS8604_RS08660	COG0628	permease
SynROS8604_RS08670	COG0426	domain, Protein
SynROS8604_RS08670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynROS8604_RS08680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynROS8604_RS08685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynROS8604_RS08690	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynROS8604_RS08690	COG0022	dehydrogenase e1 component
SynROS8604_RS08700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynROS8604_RS08705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynROS8604_RS08710	COG0572	uridine kinase
SynROS8604_RS08735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynROS8604_RS08760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynROS8604_RS08790	COG0358	DNA primase activity
SynROS8604_RS08830	COG0632	four-way junction helicase activity
SynROS8604_RS08835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynROS8604_RS08845	COG0587	DNA-directed DNA polymerase activity
SynROS8604_RS08850	COG0154	amidase activity
SynROS8604_RS08860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynROS8604_RS08865	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynROS8604_RS08870	COG1366	Belongs to the anti-sigma-factor antagonist family
SynROS8604_RS08875	COG0505	Belongs to the CarA family
SynROS8604_RS08880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynROS8604_RS08885	COG1132	(ABC) transporter
SynROS8604_RS08895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynROS8604_RS08965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynROS8604_RS09175	COG0612	Peptidase, M16
SynROS8604_RS09195	COG1136	(ABC) transporter
SynROS8604_RS09205	COG1216	Glycosyl transferase, family 2
SynROS8604_RS09225	COG1836	PFAM Integral membrane protein DUF92
SynROS8604_RS09240	COG3639	organic phosphonate transmembrane transporter activity
SynROS8604_RS09245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynROS8604_RS09245	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynROS8604_RS09250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynROS8604_RS09255	COG0436	Aminotransferase
SynROS8604_RS09265	COG1573	uracil-dna glycosylase
SynROS8604_RS09270	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynROS8604_RS09275	COG0793	Belongs to the peptidase S41A family
SynROS8604_RS09295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynROS8604_RS09315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynROS8604_RS09320	COG1494	fructose-1,6-bisphosphatase
SynROS8604_RS09325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynROS8604_RS09330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynROS8604_RS09335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynROS8604_RS09340	COG0363	glucosamine-6-phosphate deaminase activity
SynROS8604_RS09355	COG0129	dihydroxy-acid dehydratase activity
SynROS8604_RS09365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynROS8604_RS09395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynROS8604_RS09400	COG0047	phosphoribosylformylglycinamidine synthase activity
SynROS8604_RS09405	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynROS8604_RS09410	COG0191	fructose-bisphosphate aldolase activity
SynROS8604_RS09420	COG0673	inositol 2-dehydrogenase activity
SynROS8604_RS09430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynROS8604_RS09435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynROS8604_RS09445	COG3954	Phosphoribulokinase
SynROS8604_RS09450	COG0473	3-isopropylmalate dehydrogenase activity
SynROS8604_RS09455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynROS8604_RS09460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynROS8604_RS09475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynROS8604_RS09490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynROS8604_RS09495	COG2197	response regulator
SynROS8604_RS09505	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynROS8604_RS09520	COG0517	IMP dehydrogenase activity
SynROS8604_RS09530	COG1376	ErfK ybiS ycfS ynhG family protein
SynROS8604_RS09560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynROS8604_RS09605	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynROS8604_RS09615	COG1121	(ABC) transporter
SynROS8604_RS09630	COG0701	Predicted permease
SynROS8604_RS09635	COG2010	Cytochrome c
SynROS8604_RS09645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynROS8604_RS09650	COG1121	(ABC) transporter
SynROS8604_RS09705	COG2032	superoxide dismutase activity
SynROS8604_RS09850	COG0730	response to heat
SynROS8604_RS10015	COG0500	methyltransferase
SynROS8604_RS10050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynROS8604_RS10055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS10075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SynROS8604_RS10085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynROS8604_RS10085	COG0284	orotidine-5'-phosphate decarboxylase activity
SynROS8604_RS10120	COG0180	Tryptophanyl-tRNA synthetase
SynROS8604_RS10135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SynROS8604_RS10145	COG0837	glucose binding
SynROS8604_RS10150	COG0083	homoserine kinase activity
SynROS8604_RS10155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS10160	COG0339	signal peptide processing
SynROS8604_RS10190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynROS8604_RS10195	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynROS8604_RS10235	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynROS8604_RS10240	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynROS8604_RS10250	COG3794	PFAM blue (type 1) copper domain protein
SynROS8604_RS10285	COG0542	response to heat
SynROS8604_RS10295	COG0140	phosphoribosyl-ATP diphosphatase activity
SynROS8604_RS10295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynROS8604_RS10310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS10350	COG0159	tryptophan synthase activity
SynROS8604_RS10370	COG0418	dihydroorotase activity
SynROS8604_RS10375	COG0659	secondary active sulfate transmembrane transporter activity
SynROS8604_RS10400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynROS8604_RS10405	COG1845	cytochrome c oxidase, subunit III
SynROS8604_RS10415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynROS8604_RS10425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynROS8604_RS10430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynROS8604_RS10445	COG0456	acetyltransferase
SynROS8604_RS10455	COG1132	(ABC) transporter
SynROS8604_RS10460	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynROS8604_RS10465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynROS8604_RS10470	COG3842	ATPase activity
SynROS8604_RS10475	COG0251	oxidation-reduction process
SynROS8604_RS10510	COG0492	ferredoxin-NADP+ reductase activity
SynROS8604_RS10520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynROS8604_RS10530	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS10535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynROS8604_RS10540	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynROS8604_RS10565	COG4451	ribulose bisphosphate carboxylase, small
SynROS8604_RS10570	COG1850	ribulose-bisphosphate carboxylase activity
SynROS8604_RS10575	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynROS8604_RS10585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynROS8604_RS10590	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynROS8604_RS10605	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynROS8604_RS10610	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynROS8604_RS10615	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynROS8604_RS10640	COG0730	response to heat
SynROS8604_RS10645	COG0095	Lipoate-protein ligase
SynROS8604_RS10650	COG0517	IMP dehydrogenase activity
SynROS8604_RS10650	COG1994	Peptidase M50
SynROS8604_RS10655	COG0135	phosphoribosylanthranilate isomerase activity
SynROS8604_RS10665	COG0302	gtp cyclohydrolase
SynROS8604_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
SynROS8604_RS10675	COG0825	malonyl-CoA metabolic process
SynROS8604_RS10680	COG5322	oxidoreductase activity
SynROS8604_RS10685	COG3396	Phenylacetate-CoA oxygenase
SynROS8604_RS10695	COG0539	negative regulation of cytoplasmic translation
SynROS8604_RS10730	COG0028	Belongs to the TPP enzyme family
SynROS8604_RS10735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS10740	COG0582	viral genome integration into host DNA
SynROS8604_RS10745	COG2226	methyltransferase
SynROS8604_RS10755	COG0528	UMP kinase activity
SynROS8604_RS10760	COG0233	cytoplasmic translational termination
SynROS8604_RS10765	COG0644	oxidoreductase
SynROS8604_RS10770	COG0415	Belongs to the DNA photolyase family
SynROS8604_RS10775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynROS8604_RS10780	COG0768	penicillin binding
SynROS8604_RS10800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynROS8604_RS10805	COG0681	Belongs to the peptidase S26 family
SynROS8604_RS10825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynROS8604_RS10835	COG0442	prolyl-tRNA aminoacylation
SynROS8604_RS10845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynROS8604_RS10850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynROS8604_RS10865	COG0629	single-stranded DNA binding
SynROS8604_RS10880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynROS8604_RS10890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynROS8604_RS10895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS10910	COG0181	hydroxymethylbilane synthase activity
SynROS8604_RS10925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynROS8604_RS10930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynROS8604_RS10945	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynROS8604_RS10950	COG0523	cobalamin synthesis protein
SynROS8604_RS10975	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynROS8604_RS11000	COG0708	Exodeoxyribonuclease III
SynROS8604_RS11005	COG0277	FAD linked oxidase domain protein
SynROS8604_RS11010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynROS8604_RS11025	COG1666	GTP binding
SynROS8604_RS11285	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynROS8604_RS11290	COG1218	3'(2'),5'-bisphosphate nucleotidase
SynROS8604_RS11295	COG1185	polyribonucleotide nucleotidyltransferase activity
SynROS8604_RS11300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynROS8604_RS11305	COG0750	zinc metalloprotease
SynROS8604_RS11310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynROS8604_RS11320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynROS8604_RS11330	COG0706	membrane insertase activity
SynROS8604_RS11340	COG0594	ribonuclease P activity
SynROS8604_RS11345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SynROS8604_RS11360	COG0616	signal peptide processing
SynROS8604_RS11365	COG0697	spore germination
SynROS8604_RS11370	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS11385	COG1842	Phage shock protein A
SynROS8604_RS11390	COG3118	belongs to the thioredoxin family
SynROS8604_RS11395	COG0436	Aminotransferase
SynROS8604_RS11400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynROS8604_RS11400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynROS8604_RS11405	COG0739	heme binding
SynROS8604_RS11410	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS11415	COG1136	(ABC) transporter
SynROS8604_RS11415	COG0577	efflux transmembrane transporter activity
SynROS8604_RS11420	COG1007	ATP synthesis coupled electron transport
SynROS8604_RS11425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynROS8604_RS11440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynROS8604_RS11475	COG1845	cytochrome c oxidase, subunit III
SynROS8604_RS11480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynROS8604_RS11490	COG1612	heme a metabolic process
SynROS8604_RS11495	COG0109	protoheme IX farnesyltransferase activity
SynROS8604_RS11515	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynROS8604_RS11525	COG0459	protein refolding
SynROS8604_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
SynROS8604_RS11540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynROS8604_RS11550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynROS8604_RS11555	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynROS8604_RS11560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynROS8604_RS11565	COG0248	Ppx GppA phosphatase
SynROS8604_RS11585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynROS8604_RS11590	COG0739	heme binding
SynROS8604_RS11595	COG0723	plastoquinol--plastocyanin reductase activity
SynROS8604_RS11605	COG0805	protein transport
SynROS8604_RS11615	COG0194	GDP metabolic process
SynROS8604_RS11630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynROS8604_RS11635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS11645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynROS8604_RS11665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynROS8604_RS11685	COG0335	large ribosomal subunit rRNA binding
SynROS8604_RS11695	COG0024	Methionine aminopeptidase
SynROS8604_RS11700	COG3000	fatty acid hydroxylase
SynROS8604_RS11700	COG0300	oxidoreductase activity
SynROS8604_RS11705	COG0857	belongs to the CobB CobQ family
SynROS8604_RS11760	COG0776	regulation of translation
SynROS8604_RS11815	COG3551	Protein conserved in bacteria
SynROS8604_RS11840	COG3321	synthase
SynROS8604_RS11840	COG0604	alcohol dehydrogenase
SynROS8604_RS12040	COG2211	Major facilitator Superfamily
SynROS8604_RS12045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynROS8604_RS12060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynROS8604_RS12105	COG0284	orotidine-5'-phosphate decarboxylase activity
SynROS8604_RS12110	COG3386	PFAM SMP-30 Gluconolaconase
SynROS8604_RS12120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynROS8604_RS12130	COG2197	response regulator
SynROS8604_RS12145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynROS8604_RS12155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynROS8604_RS12165	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynROS8604_RS12170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynROS8604_RS12175	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynROS8604_RS12185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynROS8604_RS12195	COG0151	Belongs to the GarS family
SynROS8604_RS12200	COG5002	protein histidine kinase activity
SynROS8604_RS12205	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynROS8604_RS12210	COG4251	negative regulation of phosphorylation
SynROS8604_RS12220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynROS8604_RS12225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynROS8604_RS12230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynROS8604_RS12235	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynROS8604_RS12240	COG0217	transcriptional regulatory protein
SynROS8604_RS12275	COG1214	PFAM Peptidase M22, glycoprotease
SynROS8604_RS12275	COG0456	acetyltransferase
SynROS8604_RS12280	COG2223	nitrite transmembrane transporter activity
SynROS8604_RS12330	COG0363	glucosamine-6-phosphate deaminase activity
SynROS8604_RS12335	COG2247	cell wall binding repeat
SynROS8604_RS12335	COG2385	sporulation resulting in formation of a cellular spore
SynROS8604_RS12340	COG1234	tRNA 3'-trailer cleavage
SynROS8604_RS12345	COG2010	Cytochrome c
SynROS8604_RS12360	COG2264	protein methyltransferase activity
SynROS8604_RS12365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynROS8604_RS12385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynROS8604_RS12435	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynROS8604_RS12440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SynROS8604_RS12460	COG0459	protein refolding
SynROS8604_RS12465	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynROS8604_RS12470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynROS8604_RS12475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynROS8604_RS12490	COG0387	Pfam Sodium calcium exchanger
SynROS8604_RS12495	COG0006	proline dipeptidase activity
SynROS8604_RS12500	COG1253	flavin adenine dinucleotide binding
SynROS8604_RS12505	COG1160	GTP binding
SynROS8604_RS12510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynROS8604_RS12515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynROS8604_RS12515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynROS8604_RS12520	COG0686	Belongs to the AlaDH PNT family
SynROS8604_RS12540	COG3012	SEC-C Motif Domain Protein
SynROS8604_RS12545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynROS8604_RS12555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynROS8604_RS12565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynROS8604_RS12570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynROS8604_RS12575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynROS8604_RS12580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynROS8604_RS12585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynROS8604_RS12590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynROS8604_RS12595	COG0356	it plays a direct role in the translocation of protons across the membrane
SynROS8604_RS12605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynROS8604_RS12610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynROS8604_RS12630	COG0772	Belongs to the SEDS family
SynROS8604_RS12640	COG1333	cytochrome c biogenesis protein
SynROS8604_RS12645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynROS8604_RS12655	COG0347	Belongs to the P(II) protein family
SynROS8604_RS12660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SynROS8604_RS12670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynROS8604_RS12680	COG0114	fumarate hydratase activity
SynROS8604_RS12685	COG4581	dead DEAH box helicase
SynROS8604_RS12690	COG0156	8-amino-7-oxononanoate synthase activity
SynROS8604_RS12700	COG2226	methyltransferase
SynROS8604_RS12705	COG4106	trans-aconitate 2-methyltransferase activity
SynROS8604_RS12705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynROS8604_RS12715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynROS8604_RS12730	COG0357	Ribosomal RNA small subunit methyltransferase G
SynROS8604_RS12765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynROS8604_RS12775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynROS8604_RS12780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynROS8604_RS12785	COG0085	RNA polymerase activity
SynROS8604_RS12790	COG0084	hydrolase, TatD family'
SynROS8604_RS12795	COG0268	Binds directly to 16S ribosomal RNA
SynROS8604_RS12800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynROS8604_RS12805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynROS8604_RS12810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynROS8604_RS12830	COG2205	protein histidine kinase activity
SynROS8604_RS12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynROS8604_RS12840	COG0641	radical SAM
SynROS8604_RS12850	COG0779	Required for maturation of 30S ribosomal subunits
SynROS8604_RS12855	COG0195	Participates in both transcription termination and antitermination
SynROS8604_RS12865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynROS8604_RS12930	COG2988	succinylglutamate desuccinylase activity
SynROS8604_RS12935	COG0435	Glutathione S-transferase
SynROS8604_RS12945	COG0488	(ABC) transporter
SynROS8604_RS12955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynROS8604_RS12960	COG3842	ATPase activity
SynROS8604_RS12965	COG1193	negative regulation of DNA recombination
SynROS8604_RS12975	COG0113	porphobilinogen synthase activity
SynROS8604_RS12980	COG0484	heat shock protein binding
SynROS8604_RS12990	COG0659	secondary active sulfate transmembrane transporter activity
SynROS8604_RS13090	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynROS8604_RS13115	COG0242	peptide deformylase activity
SynROS8604_RS13265	COG0116	Belongs to the methyltransferase superfamily
SynROS8604_RS13285	COG1196	nuclear chromosome segregation
SynROS8604_RS13295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynROS8604_RS13310	COG0439	Biotin carboxylase
SynROS8604_RS13325	COG0515	serine threonine protein kinase
SynROS8604_RS13340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS13345	COG4178	(ABC) transporter
SynROS8604_RS13350	COG0537	adenosine 5'-monophosphoramidase activity
SynROS8604_RS13365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynROS8604_RS13380	COG0242	peptide deformylase activity
SynROS8604_RS13390	COG0235	Class ii aldolase
SynROS8604_RS13395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynROS8604_RS13410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynROS8604_RS13415	COG0719	Fe-S assembly protein
SynROS8604_RS13420	COG0396	ATPase activity
SynROS8604_RS13425	COG0719	Fe-S assembly protein
SynROS8604_RS13430	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SynROS8604_RS13450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynROS8604_RS13525	COG2814	Major facilitator Superfamily
SynROS8604_RS13535	COG0033	Phosphoglucomutase
SynROS8604_RS13550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynROS8604_RS13575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynROS8604_RS13580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynROS8604_RS13585	COG0175	sulfate reduction
SynROS8604_RS13590	COG1252	NADH dehydrogenase
SynROS8604_RS13595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynROS8604_RS13605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynROS8604_RS13610	COG0569	domain protein
SynROS8604_RS13615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynROS8604_RS13640	COG0488	(ABC) transporter
SynROS8604_RS13650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynROS8604_RS13665	COG1643	Atp-dependent helicase
SynROS8604_RS13670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynROS8604_RS13680	COG1570	exodeoxyribonuclease VII activity
SynROS8604_RS13685	COG1722	exodeoxyribonuclease VII activity
SynROS8604_RS13730	COG0483	inositol monophosphate 1-phosphatase activity
SynROS8604_RS13735	COG1538	Outer membrane efflux protein
SynROS8604_RS13745	COG1968	undecaprenyl-diphosphatase activity
SynROS8604_RS13755	COG1555	photosystem II stabilization
SynROS8604_RS13760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynROS8604_RS13765	COG4243	Vitamin k epoxide reductase
SynROS8604_RS13770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynROS8604_RS13785	COG1032	radical SAM domain protein
SynROS8604_RS13840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynROS8604_RS13850	COG0463	Glycosyl transferase, family 2
SynROS8604_RS13850	COG0457	Tetratricopeptide repeat
SynROS8604_RS13855	COG1587	Uroporphyrinogen-III synthase
SynROS8604_RS13870	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynROS8604_RS13875	COG0316	Belongs to the HesB IscA family
SynROS8604_RS13895	COG1090	epimerase
SynROS8604_RS13900	COG3263	regulation of cellular component size
SynROS8604_RS13915	COG0484	heat shock protein binding
SynROS8604_RS13920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynROS8604_RS13925	COG3659	wide pore channel activity
SynROS8604_RS13930	COG3659	wide pore channel activity
SynROS8604_RS13970	COG1122	ATPase activity
SynROS8604_RS13980	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS13990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynROS8604_RS13995	COG2217	Heavy metal translocating P-type atpase
SynROS8604_RS14000	COG3063	Type IV pilus biogenesis stability protein PilW
SynROS8604_RS14005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynROS8604_RS14015	COG0416	fatty acid biosynthetic process
SynROS8604_RS14020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynROS8604_RS14025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynROS8604_RS14030	COG0318	PFAM AMP-dependent synthetase and ligase
SynROS8604_RS14030	COG0204	Acyl-transferase
SynROS8604_RS14040	COG1214	PFAM Peptidase M22, glycoprotease
SynROS8604_RS14050	COG0617	tRNA 3'-terminal CCA addition
SynROS8604_RS14060	COG1562	ergosterol biosynthetic process
SynROS8604_RS14065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynROS8604_RS14065	COG0493	'glutamate synthase
SynROS8604_RS14080	COG0583	DNA-binding transcription factor activity
SynROS8604_RS14090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynROS8604_RS14110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynROS8604_RS14120	COG2197	response regulator
SynROS8604_RS14130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynROS8604_RS14135	COG0713	ATP synthesis coupled electron transport
SynROS8604_RS14140	COG0839	Belongs to the complex I subunit 6 family
SynROS8604_RS14145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynROS8604_RS14150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynROS8604_RS14155	COG0372	Belongs to the citrate synthase family
SynROS8604_RS14175	COG1420	regulation of RNA biosynthetic process
SynROS8604_RS14190	COG0133	tryptophan synthase activity
SynROS8604_RS14195	COG1073	alpha beta
SynROS8604_RS14195	COG2226	methyltransferase
SynROS8604_RS14200	COG0023	Translation Initiation Factor
SynROS8604_RS14205	COG0529	Catalyzes the synthesis of activated sulfate
SynROS8604_RS14210	COG0628	permease
SynROS8604_RS14215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynROS8604_RS14225	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynROS8604_RS14230	COG0564	pseudouridine synthase activity
SynROS8604_RS14235	COG0745	RESPONSE REGULATOR receiver
SynROS8604_RS14245	COG1104	cysteine desulfurase activity
SynROS8604_RS14260	COG0275	rRNA processing
SynROS8604_RS14265	COG0649	NAD binding
SynROS8604_RS14275	COG0824	Thioesterase
SynROS8604_RS14295	COG4948	Mandelate Racemase Muconate Lactonizing
SynROS8604_RS14300	COG1575	Belongs to the MenA family. Type 1 subfamily
SynROS8604_RS14310	COG0189	ligase activity
SynROS8604_RS14315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynROS8604_RS14330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynROS8604_RS14335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynROS8604_RS14350	COG0252	asparaginase activity
SynROS8604_RS14355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynROS8604_RS14365	COG0018	arginyl-trna synthetase
SynROS8604_RS14400	COG0668	transmembrane transport
SynROS8604_RS14435	COG0157	Belongs to the NadC ModD family
SynROS8604_RS14440	COG0154	amidase activity
SynROS8604_RS14455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynROS8604_RS14465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SynROS8604_RS14470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynROS8604_RS14475	COG4172	Belongs to the ABC transporter superfamily
SynROS8604_RS14480	COG2197	response regulator
SynROS8604_RS14490	COG0564	pseudouridine synthase activity
SynROS8604_RS14500	COG0589	response to stress
SynROS8604_RS14505	COG0126	phosphoglycerate kinase activity
SynROS8604_RS14515	COG2084	Dehydrogenase
SynROS8604_RS14525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynROS8604_RS14530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynROS8604_RS14560	COG0167	dihydroorotate dehydrogenase activity
SynROS8604_RS14565	COG0328	RNA-DNA hybrid ribonuclease activity
SynROS8604_RS14575	COG0222	ribosome binding
SynROS8604_RS14580	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynROS8604_RS14585	COG0081	regulation of translation
SynROS8604_RS14590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynROS8604_RS14595	COG0250	Participates in transcription elongation, termination and antitermination
SynROS8604_RS14600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynROS8604_RS14605	COG0542	response to heat
SynROS8604_RS14610	COG0346	lactoylglutathione lyase activity
SynROS8604_RS14615	COG0148	phosphopyruvate hydratase activity
SynROS8604_RS14620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynROS8604_RS14670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynROS8604_RS14675	COG0237	dephospho-CoA kinase activity
SynROS8604_RS14685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynROS8604_RS14695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynROS8604_RS14695	COG2022	thiamine diphosphate biosynthetic process
SynROS8604_RS14700	COG0105	UTP biosynthetic process
SynROS8604_RS14705	COG1166	arginine decarboxylase activity
SynROS8604_RS14720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynROS8604_RS14725	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynROS8604_RS14735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynROS8604_RS14760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SynROS8604_RS14770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SynROS8604_RS14775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynROS8604_RS14775	COG0426	domain, Protein
SynROS8604_RS14780	COG0426	domain, Protein
SynROS8604_RS14780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynROS8604_RS14785	COG1773	rubredoxin
SynROS8604_RS14795	COG1741	Belongs to the pirin family
SynROS8604_RS14810	COG0509	glycine decarboxylation via glycine cleavage system
SynROS8604_RS14815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynROS8604_RS14835	COG0359	binds to the 23S rRNA
SynROS8604_RS14840	COG0305	Participates in initiation and elongation during chromosome replication
SynROS8604_RS14840	COG1372	Participates in initiation and elongation during chromosome replication
SynROS8604_RS14840	COG1372	Participates in initiation and elongation during chromosome replication
SynROS8604_RS14840	COG0305	Participates in initiation and elongation during chromosome replication
SynROS8604_RS14865	COG0445	tRNA wobble uridine modification
SynROS8604_RS14910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynROS8604_RS14925	COG0398	Pfam SNARE associated Golgi protein
SynROS8604_RS14950	COG1131	(ABC) transporter
SynROS8604_RS14955	COG0668	transmembrane transport
SynROS8604_RS14960	COG0525	valine-tRNA ligase activity
SynROS8604_RS14985	COG4221	oxidoreductase activity
SynROS8604_RS15025	COG3956	TIGRFAM MazG family protein
SynROS8604_RS15030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynROS8604_RS15035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SynROS8604_RS15040	COG0010	Belongs to the arginase family
SynROS8604_RS15050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynROS8604_RS15055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynROS8604_RS15060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS15065	COG0783	Belongs to the Dps family
SynROS8604_RS15075	COG0504	CTP synthase activity
SynROS8604_RS15080	COG0602	queuosine metabolic process
SynROS8604_RS15085	COG4574	serine-type endopeptidase inhibitor activity
SynROS8604_RS15090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynROS8604_RS15105	COG0531	amino acid
SynROS8604_RS15135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SynROS8604_RS15140	COG0830	nickel cation binding
SynROS8604_RS15145	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SynROS8604_RS15150	COG0829	nickel cation binding
SynROS8604_RS15155	COG0831	urea catabolic process
SynROS8604_RS15160	COG0832	Belongs to the urease beta subunit family
SynROS8604_RS15165	COG0804	urea catabolic process
SynROS8604_RS15170	COG2308	Evidence 4 Homologs of previously reported genes of
SynROS8604_RS15190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynROS8604_RS15195	COG0746	molybdenum cofactor guanylyltransferase activity
SynROS8604_RS15200	COG2223	nitrite transmembrane transporter activity
SynROS8604_RS15205	COG0243	molybdopterin cofactor binding
SynROS8604_RS15220	COG0315	cyclic pyranopterin monophosphate synthase activity
SynROS8604_RS15240	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynROS8604_RS15245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynROS8604_RS15260	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynROS8604_RS15265	COG2116	formate transmembrane transporter activity
SynROS8604_RS15275	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynROS8604_RS15280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynROS8604_RS15290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynROS8604_RS15295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynROS8604_RS15300	COG0170	dolichyl monophosphate biosynthetic process
SynROS8604_RS15305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynROS8604_RS15310	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynROS8604_RS15330	COG0788	formyltetrahydrofolate deformylase activity
SynROS8604_RS15340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynROS8604_RS15355	COG0443	Heat shock 70 kDa protein
SynROS8604_RS15360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynROS8604_RS15370	COG0360	Binds together with S18 to 16S ribosomal RNA
SynROS8604_RS15380	COG0137	argininosuccinate synthase activity
SynROS8604_RS15395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynROS8604_RS15410	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynROS8604_RS15415	COG0438	transferase activity, transferring glycosyl groups
SynROS8604_RS15425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynROS8604_RS15430	COG0497	DNA recombination
SynROS8604_RS15435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynROS8604_RS15445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine