locus-tag	class	description
EVJ50_RS00020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVJ50_RS00030	COG0740	serine-type endopeptidase activity
EVJ50_RS00045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EVJ50_RS00055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EVJ50_RS00075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVJ50_RS00080	COG2066	Belongs to the glutaminase family
EVJ50_RS00080	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EVJ50_RS00085	COG4948	Mandelate Racemase Muconate Lactonizing
EVJ50_RS00105	COG0402	S-adenosylhomocysteine deaminase activity
EVJ50_RS00125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVJ50_RS00130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVJ50_RS00135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EVJ50_RS00150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVJ50_RS00155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVJ50_RS00160	COG0134	indole-3-glycerol-phosphate synthase activity
EVJ50_RS00165	COG4251	negative regulation of phosphorylation
EVJ50_RS00170	COG0784	Response regulator, receiver
EVJ50_RS00200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVJ50_RS00215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EVJ50_RS00220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EVJ50_RS00230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EVJ50_RS00235	COG1104	cysteine desulfurase activity
EVJ50_RS00240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVJ50_RS00250	COG0706	membrane insertase activity
EVJ50_RS00260	COG0594	ribonuclease P activity
EVJ50_RS00280	COG0616	signal peptide processing
EVJ50_RS00285	COG0697	spore germination
EVJ50_RS00305	COG1842	Phage shock protein A
EVJ50_RS00310	COG0436	Aminotransferase
EVJ50_RS00315	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EVJ50_RS00315	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EVJ50_RS00320	COG0739	heme binding
EVJ50_RS00325	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS00335	COG1136	(ABC) transporter
EVJ50_RS00340	COG1007	ATP synthesis coupled electron transport
EVJ50_RS00345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVJ50_RS00360	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EVJ50_RS00390	COG1845	cytochrome c oxidase, subunit III
EVJ50_RS00395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVJ50_RS00410	COG0109	protoheme IX farnesyltransferase activity
EVJ50_RS00430	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EVJ50_RS00440	COG0459	protein refolding
EVJ50_RS00450	COG1028	Short-chain dehydrogenase reductase Sdr
EVJ50_RS00470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EVJ50_RS00475	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVJ50_RS00480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EVJ50_RS00505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EVJ50_RS00510	COG0739	heme binding
EVJ50_RS00515	COG0723	plastoquinol--plastocyanin reductase activity
EVJ50_RS00525	COG0805	protein transport
EVJ50_RS00535	COG0194	GDP metabolic process
EVJ50_RS00550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EVJ50_RS00555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVJ50_RS00565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EVJ50_RS00570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVJ50_RS00575	COG0012	GTP binding
EVJ50_RS00595	COG0601	transmembrane transport
EVJ50_RS00605	COG0460	homoserine dehydrogenase
EVJ50_RS00610	COG2166	iron-sulfur cluster assembly
EVJ50_RS00625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EVJ50_RS00630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EVJ50_RS00635	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EVJ50_RS00650	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EVJ50_RS00655	COG2010	Cytochrome c
EVJ50_RS00665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVJ50_RS00675	COG3118	belongs to the thioredoxin family
EVJ50_RS00680	COG0516	GMP reductase activity
EVJ50_RS00690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVJ50_RS00695	COG0644	oxidoreductase
EVJ50_RS00700	COG1543	Belongs to the glycosyl hydrolase 57 family
EVJ50_RS00705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVJ50_RS00710	COG0395	ABC-type sugar transport system, permease component
EVJ50_RS00745	COG4969	Belongs to the N-Me-Phe pilin family
EVJ50_RS00775	COG0531	amino acid
EVJ50_RS00790	COG2963	transposase activity
EVJ50_RS00825	COG0628	permease
EVJ50_RS00850	COG3264	Mechanosensitive ion channel
EVJ50_RS00850	COG1511	domain protein
EVJ50_RS00860	COG0641	radical SAM
EVJ50_RS00905	COG0011	TIGRFAM Protein of
EVJ50_RS00925	COG0366	Alpha amylase catalytic
EVJ50_RS00945	COG1480	7TM receptor with intracellular HD hydrolase
EVJ50_RS00955	COG0142	geranyltranstransferase activity
EVJ50_RS00975	COG1254	Belongs to the acylphosphatase family
EVJ50_RS00980	COG1797	cobyrinic acid a,c-diamide synthase activity
EVJ50_RS00985	COG3409	Peptidoglycan-binding domain 1 protein
EVJ50_RS00985	COG3429	Glucose-6-phosphate dehydrogenase subunit
EVJ50_RS00990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EVJ50_RS00995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVJ50_RS01010	COG2205	protein histidine kinase activity
EVJ50_RS01020	COG0308	aminopeptidase N
EVJ50_RS01035	COG0776	regulation of translation
EVJ50_RS01060	COG1803	Methylglyoxal synthase
EVJ50_RS01060	COG1597	lipid kinase activity
EVJ50_RS01080	COG0628	permease
EVJ50_RS01085	COG1064	alcohol dehydrogenase
EVJ50_RS01110	COG0574	Belongs to the PEP-utilizing enzyme family
EVJ50_RS01110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EVJ50_RS01145	COG0475	glutathione-regulated potassium exporter activity
EVJ50_RS01155	COG0702	epimerase
EVJ50_RS01165	COG0406	alpha-ribazole phosphatase activity
EVJ50_RS01170	COG0166	Belongs to the GPI family
EVJ50_RS01225	COG3300	MHYT domain
EVJ50_RS01225	COG5001	Diguanylate cyclase
EVJ50_RS01270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EVJ50_RS01310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EVJ50_RS01320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVJ50_RS01345	COG0347	Belongs to the P(II) protein family
EVJ50_RS01360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EVJ50_RS01380	COG2233	PERMEase
EVJ50_RS01385	COG3239	Fatty acid desaturase
EVJ50_RS01390	COG0724	RNA recognition motif
EVJ50_RS01460	COG0625	glutathione transferase activity
EVJ50_RS01485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVJ50_RS01515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EVJ50_RS01530	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
EVJ50_RS01545	COG1187	pseudouridine synthase activity
EVJ50_RS01550	COG5002	protein histidine kinase activity
EVJ50_RS01555	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS01560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS01570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EVJ50_RS01575	COG1982	Orn Lys Arg decarboxylase major
EVJ50_RS01600	COG0542	response to heat
EVJ50_RS01610	COG0019	diaminopimelate decarboxylase activity
EVJ50_RS01620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVJ50_RS01625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EVJ50_RS01635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVJ50_RS01640	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EVJ50_RS01685	COG0589	response to stress
EVJ50_RS01685	COG0475	glutathione-regulated potassium exporter activity
EVJ50_RS01690	COG1132	(ABC) transporter
EVJ50_RS01700	COG0724	RNA recognition motif
EVJ50_RS01715	COG0513	Belongs to the DEAD box helicase family
EVJ50_RS01725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVJ50_RS01730	COG1074	ATP-dependent DNA helicase activity
EVJ50_RS01735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EVJ50_RS01755	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EVJ50_RS01770	COG0271	Belongs to the BolA IbaG family
EVJ50_RS01775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EVJ50_RS01785	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS01810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EVJ50_RS01835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVJ50_RS01840	COG0640	Transcriptional regulator
EVJ50_RS01865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EVJ50_RS01895	COG3328	transposase activity
EVJ50_RS01945	COG0500	methyltransferase
EVJ50_RS01975	COG0651	ATP synthesis coupled electron transport
EVJ50_RS01980	COG1006	Multisubunit Na H antiporter MnhC subunit
EVJ50_RS02000	COG3300	MHYT domain
EVJ50_RS02000	COG5001	Diguanylate cyclase
EVJ50_RS02020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVJ50_RS02035	COG3437	response regulator, receiver
EVJ50_RS02060	COG2095	MarC family integral membrane protein
EVJ50_RS02145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVJ50_RS02180	COG2801	Transposase and inactivated derivatives
EVJ50_RS02190	COG1301	dicarboxylic acid transport
EVJ50_RS02225	COG2801	Transposase and inactivated derivatives
EVJ50_RS02260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVJ50_RS02265	COG2890	protein-(glutamine-N5) methyltransferase activity
EVJ50_RS02285	COG0318	PFAM AMP-dependent synthetase and ligase
EVJ50_RS02290	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EVJ50_RS02295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EVJ50_RS02305	COG3328	transposase activity
EVJ50_RS02325	COG0730	response to heat
EVJ50_RS02350	COG2133	pyrroloquinoline quinone binding
EVJ50_RS02380	COG0435	Glutathione S-transferase
EVJ50_RS02395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS02420	COG0390	transport system, permease component
EVJ50_RS02425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EVJ50_RS02455	COG2226	methyltransferase
EVJ50_RS02470	COG0295	cytidine deaminase activity
EVJ50_RS02475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVJ50_RS02490	COG3781	membrane
EVJ50_RS02495	COG2124	cytochrome p450
EVJ50_RS02535	COG0778	Nitroreductase
EVJ50_RS02545	COG2197	response regulator
EVJ50_RS02570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVJ50_RS02570	COG0284	orotidine-5'-phosphate decarboxylase activity
EVJ50_RS02575	COG0418	dihydroorotase activity
EVJ50_RS02580	COG0659	secondary active sulfate transmembrane transporter activity
EVJ50_RS02600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVJ50_RS02605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVJ50_RS02610	COG1845	cytochrome c oxidase, subunit III
EVJ50_RS02645	COG3604	Transcriptional regulator
EVJ50_RS02660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVJ50_RS02665	COG0668	transmembrane transport
EVJ50_RS02685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVJ50_RS02690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVJ50_RS02705	COG0456	acetyltransferase
EVJ50_RS02715	COG1132	(ABC) transporter
EVJ50_RS02720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EVJ50_RS02725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVJ50_RS02730	COG3842	ATPase activity
EVJ50_RS02735	COG0251	oxidation-reduction process
EVJ50_RS02750	COG0464	growth
EVJ50_RS02765	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS02770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVJ50_RS02780	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EVJ50_RS02805	COG4451	ribulose bisphosphate carboxylase, small
EVJ50_RS02810	COG1850	ribulose-bisphosphate carboxylase activity
EVJ50_RS02815	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EVJ50_RS02820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EVJ50_RS02825	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EVJ50_RS02840	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EVJ50_RS02845	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EVJ50_RS02850	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EVJ50_RS02880	COG0730	response to heat
EVJ50_RS02885	COG0095	Lipoate-protein ligase
EVJ50_RS02890	COG1994	Peptidase M50
EVJ50_RS02890	COG0517	IMP dehydrogenase activity
EVJ50_RS02895	COG0135	phosphoribosylanthranilate isomerase activity
EVJ50_RS02900	COG0302	gtp cyclohydrolase
EVJ50_RS02905	COG1028	Short-chain dehydrogenase reductase Sdr
EVJ50_RS02910	COG0825	malonyl-CoA metabolic process
EVJ50_RS02930	COG0539	negative regulation of cytoplasmic translation
EVJ50_RS02945	COG0415	Belongs to the DNA photolyase family
EVJ50_RS02970	COG0028	Belongs to the TPP enzyme family
EVJ50_RS02980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVJ50_RS02995	COG0528	UMP kinase activity
EVJ50_RS03000	COG0233	cytoplasmic translational termination
EVJ50_RS03015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EVJ50_RS03020	COG0768	penicillin binding
EVJ50_RS03035	COG0406	alpha-ribazole phosphatase activity
EVJ50_RS03040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EVJ50_RS03045	COG0681	Belongs to the peptidase S26 family
EVJ50_RS03065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EVJ50_RS03075	COG0442	prolyl-tRNA aminoacylation
EVJ50_RS03085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EVJ50_RS03090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVJ50_RS03105	COG0629	single-stranded DNA binding
EVJ50_RS03120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVJ50_RS03130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EVJ50_RS03135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS03140	COG0181	hydroxymethylbilane synthase activity
EVJ50_RS03150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EVJ50_RS03155	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EVJ50_RS03170	COG0432	Pfam Uncharacterised protein family UPF0047
EVJ50_RS03190	COG0542	response to heat
EVJ50_RS03205	COG2010	Cytochrome c
EVJ50_RS03210	COG3794	PFAM blue (type 1) copper domain protein
EVJ50_RS03225	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EVJ50_RS03260	COG1940	carbohydrate kinase activity
EVJ50_RS03265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EVJ50_RS03270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EVJ50_RS03280	COG5001	Diguanylate cyclase
EVJ50_RS03280	COG2203	Gaf domain
EVJ50_RS03280	COG4251	negative regulation of phosphorylation
EVJ50_RS03280	COG3706	GGDEF domain
EVJ50_RS03285	COG0339	signal peptide processing
EVJ50_RS03290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS03295	COG0083	homoserine kinase activity
EVJ50_RS03300	COG0837	glucose binding
EVJ50_RS03305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EVJ50_RS03315	COG0180	Tryptophanyl-tRNA synthetase
EVJ50_RS03340	COG1528	Iron-storage protein
EVJ50_RS03360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EVJ50_RS03370	COG1121	(ABC) transporter
EVJ50_RS03375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVJ50_RS03380	COG3706	GGDEF domain
EVJ50_RS03385	COG0556	nucleotide-excision repair
EVJ50_RS03400	COG4574	serine-type endopeptidase inhibitor activity
EVJ50_RS03410	COG2010	Cytochrome c
EVJ50_RS03470	COG0681	Belongs to the peptidase S26 family
EVJ50_RS03475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EVJ50_RS03485	COG1376	ErfK ybiS ycfS ynhG family protein
EVJ50_RS03500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EVJ50_RS03505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EVJ50_RS03515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EVJ50_RS03520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EVJ50_RS03525	COG2045	Belongs to the ComB family
EVJ50_RS03540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EVJ50_RS03545	COG0142	geranyltranstransferase activity
EVJ50_RS03550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EVJ50_RS03555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVJ50_RS03565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVJ50_RS03580	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS03585	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EVJ50_RS03625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVJ50_RS03635	COG1216	Glycosyl transferase, family 2
EVJ50_RS03640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVJ50_RS03650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVJ50_RS03690	COG0385	Bile acid
EVJ50_RS03695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVJ50_RS03705	COG1132	(ABC) transporter
EVJ50_RS03715	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVJ50_RS03720	COG0505	Belongs to the CarA family
EVJ50_RS03730	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EVJ50_RS03735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVJ50_RS03745	COG0154	amidase activity
EVJ50_RS03750	COG0587	DNA-directed DNA polymerase activity
EVJ50_RS03760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EVJ50_RS03765	COG0632	four-way junction helicase activity
EVJ50_RS03820	COG0358	DNA primase activity
EVJ50_RS03840	COG1121	(ABC) transporter
EVJ50_RS03850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVJ50_RS03980	COG2066	Belongs to the glutaminase family
EVJ50_RS04000	COG1132	(ABC) transporter
EVJ50_RS04025	COG1054	Belongs to the UPF0176 family
EVJ50_RS04060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVJ50_RS04065	COG0300	oxidoreductase activity
EVJ50_RS04135	COG2197	response regulator
EVJ50_RS04140	COG3979	chitinase
EVJ50_RS04150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EVJ50_RS04160	COG0174	glutamine synthetase
EVJ50_RS04165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVJ50_RS04180	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EVJ50_RS04185	COG0385	Bile acid
EVJ50_RS04230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EVJ50_RS04235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EVJ50_RS04245	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVJ50_RS04245	COG0022	dehydrogenase e1 component
EVJ50_RS04250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVJ50_RS04255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EVJ50_RS04265	COG0628	permease
EVJ50_RS04275	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EVJ50_RS04280	COG0515	serine threonine protein kinase
EVJ50_RS04310	COG2226	methyltransferase
EVJ50_RS04320	COG0174	glutamine synthetase
EVJ50_RS04330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EVJ50_RS04335	COG0590	tRNA wobble adenosine to inosine editing
EVJ50_RS04335	COG0037	tRNA processing
EVJ50_RS04350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EVJ50_RS04355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVJ50_RS04360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVJ50_RS04375	COG0612	Peptidase, M16
EVJ50_RS04380	COG0612	Peptidase, M16
EVJ50_RS04400	COG1136	(ABC) transporter
EVJ50_RS04410	COG1216	Glycosyl transferase, family 2
EVJ50_RS04415	COG0052	Belongs to the universal ribosomal protein uS2 family
EVJ50_RS04420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EVJ50_RS04430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EVJ50_RS04435	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EVJ50_RS04440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVJ50_RS04445	COG0751	glycine-tRNA ligase activity
EVJ50_RS04450	COG0644	oxidoreductase
EVJ50_RS04460	COG1217	gtp-binding protein TYPA
EVJ50_RS04485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EVJ50_RS04490	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVJ50_RS04495	COG1494	fructose-1,6-bisphosphatase
EVJ50_RS04500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVJ50_RS04505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EVJ50_RS04510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EVJ50_RS04515	COG0363	glucosamine-6-phosphate deaminase activity
EVJ50_RS04600	COG0129	dihydroxy-acid dehydratase activity
EVJ50_RS04610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EVJ50_RS04615	COG1357	PFAM Pentapeptide repeats (8 copies)
EVJ50_RS04625	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVJ50_RS04630	COG0047	phosphoribosylformylglycinamidine synthase activity
EVJ50_RS04635	COG1619	proteins homologs of microcin C7 resistance protein MccF
EVJ50_RS04640	COG0191	fructose-bisphosphate aldolase activity
EVJ50_RS04645	COG0673	inositol 2-dehydrogenase activity
EVJ50_RS04655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EVJ50_RS04660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EVJ50_RS04670	COG3954	Phosphoribulokinase
EVJ50_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
EVJ50_RS04680	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVJ50_RS04685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVJ50_RS04700	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EVJ50_RS04715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVJ50_RS04720	COG2197	response regulator
EVJ50_RS04730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EVJ50_RS04765	COG1201	RNA secondary structure unwinding
EVJ50_RS04770	COG1793	dna ligase
EVJ50_RS04775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EVJ50_RS04775	COG1793	dna ligase
EVJ50_RS04810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EVJ50_RS04815	COG1175	transmembrane transport
EVJ50_RS04820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EVJ50_RS04835	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EVJ50_RS04845	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EVJ50_RS04855	COG0740	serine-type endopeptidase activity
EVJ50_RS04865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVJ50_RS04875	COG1136	(ABC) transporter
EVJ50_RS04875	COG0577	efflux transmembrane transporter activity
EVJ50_RS04880	COG0469	pyruvate kinase activity
EVJ50_RS04900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EVJ50_RS04905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EVJ50_RS04935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVJ50_RS04955	COG0395	ABC-type sugar transport system, permease component
EVJ50_RS04960	COG1175	transmembrane transport
EVJ50_RS04965	COG1653	transport
EVJ50_RS04970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EVJ50_RS04975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVJ50_RS04980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EVJ50_RS04985	COG0326	Molecular chaperone. Has ATPase activity
EVJ50_RS04990	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EVJ50_RS05000	COG0483	inositol monophosphate 1-phosphatase activity
EVJ50_RS05015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVJ50_RS05020	COG0581	inorganic phosphate transmembrane transporter activity
EVJ50_RS05025	COG0573	inorganic phosphate transmembrane transporter activity
EVJ50_RS05030	COG0443	Heat shock 70 kDa protein
EVJ50_RS05035	COG0484	heat shock protein binding
EVJ50_RS05040	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EVJ50_RS05045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EVJ50_RS05050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVJ50_RS05055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVJ50_RS05055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVJ50_RS05060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EVJ50_RS05065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EVJ50_RS05090	COG0495	leucyl-tRNA aminoacylation
EVJ50_RS05100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EVJ50_RS05130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EVJ50_RS05135	COG0426	domain, Protein
EVJ50_RS05135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVJ50_RS05140	COG0322	excinuclease ABC activity
EVJ50_RS05150	COG3046	protein related to deoxyribodipyrimidine photolyase
EVJ50_RS05155	COG1981	membrane
EVJ50_RS05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EVJ50_RS05180	COG0646	methionine synthase
EVJ50_RS05180	COG1410	methionine synthase
EVJ50_RS05200	COG2385	sporulation resulting in formation of a cellular spore
EVJ50_RS05235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EVJ50_RS05240	COG0072	phenylalanine-tRNA ligase activity
EVJ50_RS05240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVJ50_RS05245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EVJ50_RS05250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EVJ50_RS05255	COG0557	exoribonuclease II activity
EVJ50_RS05270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVJ50_RS05305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EVJ50_RS05310	COG0739	heme binding
EVJ50_RS05320	COG1119	ATPase activity
EVJ50_RS05330	COG0450	alkyl hydroperoxide reductase
EVJ50_RS05345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVJ50_RS05350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EVJ50_RS05370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EVJ50_RS05370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EVJ50_RS05390	COG2119	membrane
EVJ50_RS05400	COG0557	exoribonuclease II activity
EVJ50_RS05405	COG0163	prenyltransferase activity
EVJ50_RS05420	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EVJ50_RS05425	COG0312	modulator of DNA gyrase
EVJ50_RS05435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EVJ50_RS05515	COG0463	Glycosyl transferase, family 2
EVJ50_RS05560	COG2801	Transposase and inactivated derivatives
EVJ50_RS05700	COG2801	Transposase and inactivated derivatives
EVJ50_RS05705	COG2801	Transposase and inactivated derivatives
EVJ50_RS05805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EVJ50_RS05820	COG0793	Belongs to the peptidase S41A family
EVJ50_RS05825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EVJ50_RS05830	COG1573	uracil-dna glycosylase
EVJ50_RS05840	COG0436	Aminotransferase
EVJ50_RS05845	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EVJ50_RS05850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVJ50_RS05850	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EVJ50_RS05855	COG3639	organic phosphonate transmembrane transporter activity
EVJ50_RS05865	COG1191	sigma factor activity
EVJ50_RS05870	COG1836	PFAM Integral membrane protein DUF92
EVJ50_RS05880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EVJ50_RS05890	COG1136	(ABC) transporter
EVJ50_RS05895	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EVJ50_RS05910	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EVJ50_RS05915	COG0659	secondary active sulfate transmembrane transporter activity
EVJ50_RS06015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVJ50_RS06025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVJ50_RS06030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVJ50_RS06040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EVJ50_RS06045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EVJ50_RS06050	COG1429	ligase activity, forming nitrogen-metal bonds
EVJ50_RS06060	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS06080	COG1132	(ABC) transporter
EVJ50_RS06095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EVJ50_RS06115	COG2801	Transposase and inactivated derivatives
EVJ50_RS06140	COG2274	protein secretion by the type I secretion system
EVJ50_RS06145	COG1115	amino acid carrier protein
EVJ50_RS06155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVJ50_RS06165	COG0799	negative regulation of ribosome biogenesis
EVJ50_RS06200	COG0367	asparagine synthase
EVJ50_RS06215	COG0668	transmembrane transport
EVJ50_RS06245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVJ50_RS06250	COG4597	amino acid ABC transporter
EVJ50_RS06255	COG0765	amino acid transport
EVJ50_RS06265	COG0076	glutamate decarboxylase activity
EVJ50_RS06300	COG0010	Belongs to the arginase family
EVJ50_RS06305	COG0375	protein maturation
EVJ50_RS06320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVJ50_RS06325	COG1116	anion transmembrane transporter activity
EVJ50_RS06385	COG0668	transmembrane transport
EVJ50_RS06420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EVJ50_RS06425	COG0482	sulfurtransferase activity
EVJ50_RS06430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EVJ50_RS06430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EVJ50_RS06435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS06440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EVJ50_RS06450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EVJ50_RS06455	COG0228	four-way junction DNA binding
EVJ50_RS06460	COG1702	phosphate starvation-inducible protein PhoH
EVJ50_RS06465	COG0670	Belongs to the BI1 family
EVJ50_RS06475	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS06490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVJ50_RS06515	COG1691	(AIR) carboxylase
EVJ50_RS06535	COG0352	thiamine-phosphate diphosphorylase activity
EVJ50_RS06540	COG0196	riboflavin kinase activity
EVJ50_RS06550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EVJ50_RS06555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EVJ50_RS06560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVJ50_RS06615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVJ50_RS06615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVJ50_RS06630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVJ50_RS06635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EVJ50_RS06640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVJ50_RS06660	COG1492	cobalamin metabolic process
EVJ50_RS06670	COG0424	maF-like protein
EVJ50_RS06680	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS06685	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS06710	COG1116	anion transmembrane transporter activity
EVJ50_RS06730	COG3437	response regulator, receiver
EVJ50_RS06755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVJ50_RS06755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVJ50_RS06780	COG0154	amidase activity
EVJ50_RS06830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVJ50_RS06835	COG0440	acetolactate synthase activity
EVJ50_RS06855	COG0702	epimerase
EVJ50_RS06865	COG2226	methyltransferase
EVJ50_RS06870	COG1187	pseudouridine synthase activity
EVJ50_RS06880	COG0492	ferredoxin-NADP+ reductase activity
EVJ50_RS06890	COG2084	Dehydrogenase
EVJ50_RS06920	COG3411	Ferredoxin
EVJ50_RS06925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EVJ50_RS06930	COG0733	neurotransmitter:sodium symporter activity
EVJ50_RS06950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVJ50_RS06950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EVJ50_RS06965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVJ50_RS06985	COG0335	large ribosomal subunit rRNA binding
EVJ50_RS06995	COG0024	Methionine aminopeptidase
EVJ50_RS07000	COG3000	fatty acid hydroxylase
EVJ50_RS07000	COG0300	oxidoreductase activity
EVJ50_RS07010	COG0857	belongs to the CobB CobQ family
EVJ50_RS07025	COG0330	HflC and HflK could
EVJ50_RS07040	COG1666	GTP binding
EVJ50_RS07115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EVJ50_RS07120	COG0277	FAD linked oxidase domain protein
EVJ50_RS07135	COG5002	protein histidine kinase activity
EVJ50_RS07135	COG5001	Diguanylate cyclase
EVJ50_RS07135	COG3447	MASE1 domain protein
EVJ50_RS07175	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EVJ50_RS07185	COG0735	belongs to the Fur family
EVJ50_RS07205	COG0523	cobalamin synthesis protein
EVJ50_RS07210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EVJ50_RS07210	COG0140	phosphoribosyl-ATP diphosphatase activity
EVJ50_RS07225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS07230	COG3339	Conserved Protein
EVJ50_RS07255	COG2010	Cytochrome c
EVJ50_RS07270	COG0159	tryptophan synthase activity
EVJ50_RS07315	COG0123	including yeast histone deacetylase and acetoin utilization protein
EVJ50_RS07345	COG2319	Wd-40 repeat
EVJ50_RS07370	COG2211	Major facilitator Superfamily
EVJ50_RS07375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EVJ50_RS07390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EVJ50_RS07395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EVJ50_RS07400	COG1799	cell septum assembly
EVJ50_RS07405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EVJ50_RS07415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVJ50_RS07420	COG1160	GTP binding
EVJ50_RS07435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVJ50_RS07445	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EVJ50_RS07455	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EVJ50_RS07475	COG0405	Gamma-glutamyltransferase
EVJ50_RS07490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EVJ50_RS07500	COG1388	LysM domain
EVJ50_RS07500	COG3942	CHAP domain
EVJ50_RS07505	COG0514	ATP-dependent DNA helicase (RecQ)
EVJ50_RS07520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EVJ50_RS07525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EVJ50_RS07530	COG0235	Class ii aldolase
EVJ50_RS07535	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EVJ50_RS07570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVJ50_RS07575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EVJ50_RS07580	COG0793	Belongs to the peptidase S41A family
EVJ50_RS07585	COG1078	dGTPase activity
EVJ50_RS07590	COG0850	regulation of cytokinetic process
EVJ50_RS07595	COG2894	cell division
EVJ50_RS07600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EVJ50_RS07620	COG2890	protein-(glutamine-N5) methyltransferase activity
EVJ50_RS07635	COG0589	response to stress
EVJ50_RS07660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVJ50_RS07665	COG0539	negative regulation of cytoplasmic translation
EVJ50_RS07675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EVJ50_RS07680	COG1070	Carbohydrate kinase
EVJ50_RS07690	COG1040	competence protein
EVJ50_RS07710	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EVJ50_RS07720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVJ50_RS07770	COG1413	lyase activity
EVJ50_RS07775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVJ50_RS07785	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EVJ50_RS07845	COG0408	coproporphyrinogen oxidase activity
EVJ50_RS07850	COG0489	protein tyrosine kinase activity
EVJ50_RS07855	COG0772	Belongs to the SEDS family
EVJ50_RS07870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EVJ50_RS07875	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EVJ50_RS07895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EVJ50_RS07900	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EVJ50_RS07905	COG1606	tRNA processing
EVJ50_RS07925	COG3001	Fructosamine kinase
EVJ50_RS07955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EVJ50_RS07970	COG3854	ATPases associated with a variety of cellular activities
EVJ50_RS07985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EVJ50_RS07990	COG0088	Forms part of the polypeptide exit tunnel
EVJ50_RS07995	COG0089	rRNA binding
EVJ50_RS08005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EVJ50_RS08010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EVJ50_RS08015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EVJ50_RS08025	COG0255	Belongs to the universal ribosomal protein uL29 family
EVJ50_RS08030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EVJ50_RS08035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EVJ50_RS08040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EVJ50_RS08045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EVJ50_RS08050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EVJ50_RS08055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EVJ50_RS08060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EVJ50_RS08065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EVJ50_RS08070	COG0200	Binds to the 23S rRNA
EVJ50_RS08075	COG0201	protein transport
EVJ50_RS08080	COG0563	adenylate kinase activity
EVJ50_RS08085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EVJ50_RS08095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EVJ50_RS08100	COG0202	RNA polymerase activity
EVJ50_RS08105	COG0203	ribosomal protein L17
EVJ50_RS08110	COG0101	tRNA pseudouridine synthase activity
EVJ50_RS08125	COG0254	rRNA binding
EVJ50_RS08130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EVJ50_RS08140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVJ50_RS08160	COG0463	Glycosyl transferase, family 2
EVJ50_RS08190	COG2885	chlorophyll binding
EVJ50_RS08205	COG1840	ABC-type Fe3 transport system, periplasmic component
EVJ50_RS08210	COG3128	pkhd-type hydroxylase
EVJ50_RS08220	COG3659	wide pore channel activity
EVJ50_RS08230	COG0310	cobalt ion transport
EVJ50_RS08235	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EVJ50_RS08240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EVJ50_RS08245	COG1122	ATPase activity
EVJ50_RS08260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVJ50_RS08270	COG0069	glutamate synthase activity
EVJ50_RS08270	COG0070	glutamate synthase
EVJ50_RS08270	COG0067	glutamate synthase
EVJ50_RS08285	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EVJ50_RS08290	COG0049	tRNA binding
EVJ50_RS08300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVJ50_RS08305	COG0051	transcription antitermination factor activity, RNA binding
EVJ50_RS08315	COG2226	methyltransferase
EVJ50_RS08330	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVJ50_RS08335	COG1530	ribonuclease E activity
EVJ50_RS08345	COG0436	Aminotransferase
EVJ50_RS08350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EVJ50_RS08360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVJ50_RS08365	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EVJ50_RS08375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EVJ50_RS08390	COG2046	Belongs to the sulfate adenylyltransferase family
EVJ50_RS08400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVJ50_RS08405	COG3536	Protein conserved in bacteria
EVJ50_RS08425	COG0540	Belongs to the ATCase OTCase family
EVJ50_RS08430	COG2094	Belongs to the DNA glycosylase MPG family
EVJ50_RS08445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVJ50_RS08465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EVJ50_RS08490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EVJ50_RS08500	COG2971	BadF BadG BcrA BcrD
EVJ50_RS08505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVJ50_RS08515	COG0739	heme binding
EVJ50_RS08515	COG0741	lytic transglycosylase activity
EVJ50_RS08515	COG1196	nuclear chromosome segregation
EVJ50_RS08525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVJ50_RS08535	COG0717	Belongs to the dCTP deaminase family
EVJ50_RS08540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EVJ50_RS08545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVJ50_RS08550	COG4372	Transposase
EVJ50_RS08570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EVJ50_RS08605	COG0066	3-isopropylmalate dehydratase activity
EVJ50_RS08610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EVJ50_RS08615	COG1546	Belongs to the CinA family
EVJ50_RS08615	COG1058	Belongs to the CinA family
EVJ50_RS08620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVJ50_RS08625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EVJ50_RS08650	COG0728	peptidoglycan biosynthetic process
EVJ50_RS08655	COG1489	DNA binding
EVJ50_RS08660	COG0004	ammonium transporteR
EVJ50_RS08665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EVJ50_RS08680	COG0138	bifunctional purine biosynthesis protein purh
EVJ50_RS08700	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EVJ50_RS08705	COG0343	queuine tRNA-ribosyltransferase activity
EVJ50_RS08715	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EVJ50_RS08725	COG0673	inositol 2-dehydrogenase activity
EVJ50_RS08730	COG1253	flavin adenine dinucleotide binding
EVJ50_RS08750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVJ50_RS08755	COG0354	folic acid binding
EVJ50_RS08765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVJ50_RS08775	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EVJ50_RS08780	COG0131	Imidazoleglycerol-phosphate dehydratase
EVJ50_RS08785	COG2091	lysine biosynthetic process via aminoadipic acid
EVJ50_RS08790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EVJ50_RS08815	COG0415	Belongs to the DNA photolyase family
EVJ50_RS08820	COG0494	nUDIX hydrolase
EVJ50_RS08830	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EVJ50_RS08830	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EVJ50_RS08840	COG1127	ABC transporter
EVJ50_RS08845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EVJ50_RS08850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS08855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS08860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS08865	COG1773	rubredoxin
EVJ50_RS08870	COG4447	cellulose binding
EVJ50_RS08905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EVJ50_RS08950	COG3220	belongs to the UPF0276 family
EVJ50_RS08955	COG2132	Multicopper oxidase
EVJ50_RS08960	COG1725	Transcriptional regulator
EVJ50_RS08965	COG1045	serine acetyltransferase
EVJ50_RS08980	COG0653	protein targeting
EVJ50_RS09010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVJ50_RS09040	COG1216	Glycosyl transferase, family 2
EVJ50_RS09060	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS09075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EVJ50_RS09080	COG0124	histidyl-tRNA synthetase
EVJ50_RS09140	COG3328	transposase activity
EVJ50_RS09225	COG2801	Transposase and inactivated derivatives
EVJ50_RS09230	COG4584	PFAM Integrase catalytic
EVJ50_RS09290	COG2801	Transposase and inactivated derivatives
EVJ50_RS09335	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS09355	COG2801	Transposase and inactivated derivatives
EVJ50_RS09415	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS09435	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS09455	COG0463	Glycosyl transferase, family 2
EVJ50_RS09455	COG1216	Glycosyl transferase, family 2
EVJ50_RS09495	COG1088	dTDP-glucose 4,6-dehydratase activity
EVJ50_RS09535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVJ50_RS09540	COG0709	Synthesizes selenophosphate from selenide and ATP
EVJ50_RS09550	COG0617	tRNA 3'-terminal CCA addition
EVJ50_RS09555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EVJ50_RS09555	COG0517	IMP dehydrogenase activity
EVJ50_RS09560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EVJ50_RS09565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EVJ50_RS09580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVJ50_RS09610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EVJ50_RS09635	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS09645	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS09650	COG1132	(ABC) transporter
EVJ50_RS09665	COG5398	heme oxygenase
EVJ50_RS09675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EVJ50_RS09680	COG0538	isocitrate dehydrogenase activity
EVJ50_RS09685	COG0247	lactate metabolic process
EVJ50_RS09690	COG3395	kinase activity
EVJ50_RS09695	COG0277	FAD linked oxidase domain protein
EVJ50_RS09720	COG0475	glutathione-regulated potassium exporter activity
EVJ50_RS09725	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EVJ50_RS09730	COG0039	L-malate dehydrogenase activity
EVJ50_RS09735	COG0058	SHG alpha-glucan phosphorylase activity
EVJ50_RS09740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EVJ50_RS09760	COG0306	phosphate transporter
EVJ50_RS09795	COG0571	ribonuclease III activity
EVJ50_RS09800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVJ50_RS09810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EVJ50_RS09820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EVJ50_RS09825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS09830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVJ50_RS09835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EVJ50_RS09840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EVJ50_RS09845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EVJ50_RS09860	COG1473	amidohydrolase
EVJ50_RS09870	COG2255	four-way junction helicase activity
EVJ50_RS09875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EVJ50_RS09880	COG0515	serine threonine protein kinase
EVJ50_RS09890	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EVJ50_RS09910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EVJ50_RS09915	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS09940	COG0629	single-stranded DNA binding
EVJ50_RS09945	COG0586	Pfam SNARE associated Golgi protein
EVJ50_RS09955	COG0802	atpase or kinase
EVJ50_RS10025	COG4251	negative regulation of phosphorylation
EVJ50_RS10080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS10085	COG2239	Acts as a magnesium transporter
EVJ50_RS10090	COG0386	Belongs to the glutathione peroxidase family
EVJ50_RS10095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVJ50_RS10100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVJ50_RS10110	COG1372	Participates in initiation and elongation during chromosome replication
EVJ50_RS10110	COG0187	DNA topoisomerase II activity
EVJ50_RS10115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EVJ50_RS10120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EVJ50_RS10145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVJ50_RS10150	COG0556	nucleotide-excision repair
EVJ50_RS10165	COG0037	tRNA processing
EVJ50_RS10175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EVJ50_RS10180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EVJ50_RS10185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EVJ50_RS10190	COG0544	peptidyl-prolyl cis-trans isomerase activity
EVJ50_RS10195	COG0740	serine-type endopeptidase activity
EVJ50_RS10210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EVJ50_RS10215	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS10220	COG2385	sporulation resulting in formation of a cellular spore
EVJ50_RS10225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EVJ50_RS10230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EVJ50_RS10245	COG2022	thiamine diphosphate biosynthetic process
EVJ50_RS10255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVJ50_RS10265	COG0768	penicillin binding
EVJ50_RS10340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EVJ50_RS10345	COG0511	ligase activity, forming carbon-carbon bonds
EVJ50_RS10350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EVJ50_RS10355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVJ50_RS10360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EVJ50_RS10365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVJ50_RS10370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVJ50_RS10375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EVJ50_RS10380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EVJ50_RS10385	COG1162	GTPase activity
EVJ50_RS10395	COG0484	heat shock protein binding
EVJ50_RS10400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EVJ50_RS10415	COG1459	type II secretion system
EVJ50_RS10420	COG2081	HI0933 family
EVJ50_RS10425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVJ50_RS10430	COG0165	Argininosuccinate lyase
EVJ50_RS10435	COG2208	phosphoserine phosphatase activity
EVJ50_RS10440	COG0552	protein localization to endoplasmic reticulum
EVJ50_RS10445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVJ50_RS10460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EVJ50_RS10470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EVJ50_RS10475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EVJ50_RS10480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVJ50_RS10490	COG0592	DNA-directed DNA polymerase activity
EVJ50_RS10495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EVJ50_RS10505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EVJ50_RS10510	COG0497	DNA recombination
EVJ50_RS10515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EVJ50_RS10525	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS10530	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EVJ50_RS10545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVJ50_RS10560	COG0137	argininosuccinate synthase activity
EVJ50_RS10570	COG0360	Binds together with S18 to 16S ribosomal RNA
EVJ50_RS10580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EVJ50_RS10585	COG0443	Heat shock 70 kDa protein
EVJ50_RS10595	COG2022	thiamine diphosphate biosynthetic process
EVJ50_RS10595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVJ50_RS10605	COG0788	formyltetrahydrofolate deformylase activity
EVJ50_RS10620	COG1049	propionate catabolic process, 2-methylcitrate cycle
EVJ50_RS10625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EVJ50_RS10635	COG0170	dolichyl monophosphate biosynthetic process
EVJ50_RS10640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EVJ50_RS10645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EVJ50_RS10650	COG0315	cyclic pyranopterin monophosphate synthase activity
EVJ50_RS10655	COG0303	'Molybdopterin
EVJ50_RS10665	COG0314	molybdopterin synthase activity
EVJ50_RS10675	COG0521	Mo-molybdopterin cofactor biosynthetic process
EVJ50_RS10680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EVJ50_RS10685	COG0746	molybdenum cofactor guanylyltransferase activity
EVJ50_RS10690	COG2223	nitrite transmembrane transporter activity
EVJ50_RS10695	COG0243	molybdopterin cofactor binding
EVJ50_RS10705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVJ50_RS10710	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EVJ50_RS10720	COG2116	formate transmembrane transporter activity
EVJ50_RS10725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVJ50_RS10745	COG5001	Diguanylate cyclase
EVJ50_RS10745	COG1716	ATPase activity
EVJ50_RS10750	COG0058	SHG alpha-glucan phosphorylase activity
EVJ50_RS10770	COG2308	Evidence 4 Homologs of previously reported genes of
EVJ50_RS10785	COG0832	Belongs to the urease beta subunit family
EVJ50_RS10790	COG0831	urea catabolic process
EVJ50_RS10795	COG0829	nickel cation binding
EVJ50_RS10800	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EVJ50_RS10805	COG0830	nickel cation binding
EVJ50_RS10810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EVJ50_RS10830	COG0411	ABC transporter
EVJ50_RS10865	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EVJ50_RS10870	COG3706	GGDEF domain
EVJ50_RS10875	COG0602	queuosine metabolic process
EVJ50_RS10880	COG0504	CTP synthase activity
EVJ50_RS10885	COG0783	Belongs to the Dps family
EVJ50_RS10890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EVJ50_RS10910	COG0010	Belongs to the arginase family
EVJ50_RS10915	COG3956	TIGRFAM MazG family protein
EVJ50_RS10925	COG3659	wide pore channel activity
EVJ50_RS10935	COG1054	Belongs to the UPF0176 family
EVJ50_RS10940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EVJ50_RS10985	COG4191	Histidine kinase
EVJ50_RS11015	COG3264	Mechanosensitive ion channel
EVJ50_RS11015	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EVJ50_RS11020	COG0668	transmembrane transport
EVJ50_RS11025	COG0583	DNA-binding transcription factor activity
EVJ50_RS11035	COG3239	Fatty acid desaturase
EVJ50_RS11040	COG0668	transmembrane transport
EVJ50_RS11045	COG0668	transmembrane transport
EVJ50_RS11060	COG1733	regulation of RNA biosynthetic process
EVJ50_RS11080	COG0668	transmembrane transport
EVJ50_RS11085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EVJ50_RS11110	COG0628	permease
EVJ50_RS11130	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EVJ50_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
EVJ50_RS11150	COG0604	alcohol dehydrogenase
EVJ50_RS11165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EVJ50_RS11175	COG0492	ferredoxin-NADP+ reductase activity
EVJ50_RS11200	COG3220	belongs to the UPF0276 family
EVJ50_RS11245	COG0702	epimerase
EVJ50_RS11280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVJ50_RS11280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVJ50_RS11285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVJ50_RS11305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EVJ50_RS11320	COG2873	o-acetylhomoserine
EVJ50_RS11335	COG0525	valine-tRNA ligase activity
EVJ50_RS11345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVJ50_RS11385	COG0445	tRNA wobble uridine modification
EVJ50_RS11395	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVJ50_RS11400	COG1372	Participates in initiation and elongation during chromosome replication
EVJ50_RS11400	COG0305	Participates in initiation and elongation during chromosome replication
EVJ50_RS11400	COG1372	Participates in initiation and elongation during chromosome replication
EVJ50_RS11400	COG0305	Participates in initiation and elongation during chromosome replication
EVJ50_RS11405	COG0359	binds to the 23S rRNA
EVJ50_RS11425	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EVJ50_RS11430	COG0509	glycine decarboxylation via glycine cleavage system
EVJ50_RS11445	COG1741	Belongs to the pirin family
EVJ50_RS11460	COG1773	rubredoxin
EVJ50_RS11460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVJ50_RS11465	COG0701	Predicted permease
EVJ50_RS11515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVJ50_RS11515	COG0426	domain, Protein
EVJ50_RS11520	COG0426	domain, Protein
EVJ50_RS11520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVJ50_RS11540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVJ50_RS11545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EVJ50_RS11585	COG0668	transmembrane transport
EVJ50_RS11610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EVJ50_RS11615	COG1166	arginine decarboxylase activity
EVJ50_RS11630	COG0105	UTP biosynthetic process
EVJ50_RS11645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVJ50_RS11645	COG2022	thiamine diphosphate biosynthetic process
EVJ50_RS11650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVJ50_RS11665	COG0237	dephospho-CoA kinase activity
EVJ50_RS11675	COG4260	virion core protein, lumpy skin disease virus
EVJ50_RS11680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EVJ50_RS11700	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EVJ50_RS11705	COG0148	phosphopyruvate hydratase activity
EVJ50_RS11710	COG0346	lactoylglutathione lyase activity
EVJ50_RS11715	COG0542	response to heat
EVJ50_RS11720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EVJ50_RS11725	COG0250	Participates in transcription elongation, termination and antitermination
EVJ50_RS11730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EVJ50_RS11735	COG0081	regulation of translation
EVJ50_RS11740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EVJ50_RS11745	COG0222	ribosome binding
EVJ50_RS11755	COG0328	RNA-DNA hybrid ribonuclease activity
EVJ50_RS11760	COG0167	dihydroorotate dehydrogenase activity
EVJ50_RS11785	COG1450	Type ii and iii secretion system protein
EVJ50_RS11810	COG0714	Associated with various cellular activities
EVJ50_RS11820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EVJ50_RS11840	COG0126	phosphoglycerate kinase activity
EVJ50_RS11845	COG0589	response to stress
EVJ50_RS11850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EVJ50_RS11855	COG0564	pseudouridine synthase activity
EVJ50_RS11865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVJ50_RS11880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EVJ50_RS11885	COG0157	Belongs to the NadC ModD family
EVJ50_RS11895	COG0018	arginyl-trna synthetase
EVJ50_RS11905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVJ50_RS11920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EVJ50_RS11925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EVJ50_RS11940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EVJ50_RS11945	COG0189	ligase activity
EVJ50_RS11955	COG1575	Belongs to the MenA family. Type 1 subfamily
EVJ50_RS11960	COG4948	Mandelate Racemase Muconate Lactonizing
EVJ50_RS11980	COG0824	Thioesterase
EVJ50_RS12005	COG0649	NAD binding
EVJ50_RS12010	COG0275	rRNA processing
EVJ50_RS12025	COG1104	cysteine desulfurase activity
EVJ50_RS12035	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS12040	COG0564	pseudouridine synthase activity
EVJ50_RS12055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EVJ50_RS12060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EVJ50_RS12065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EVJ50_RS12070	COG0628	permease
EVJ50_RS12075	COG0529	Catalyzes the synthesis of activated sulfate
EVJ50_RS12080	COG0023	Translation Initiation Factor
EVJ50_RS12085	COG0133	tryptophan synthase activity
EVJ50_RS12095	COG1420	regulation of RNA biosynthetic process
EVJ50_RS12110	COG2062	phosphohistidine phosphatase, SixA
EVJ50_RS12115	COG0372	Belongs to the citrate synthase family
EVJ50_RS12120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EVJ50_RS12125	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVJ50_RS12135	COG0713	ATP synthesis coupled electron transport
EVJ50_RS12140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVJ50_RS12155	COG2197	response regulator
EVJ50_RS12165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EVJ50_RS12185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVJ50_RS12195	COG0583	DNA-binding transcription factor activity
EVJ50_RS12210	COG0493	'glutamate synthase
EVJ50_RS12210	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EVJ50_RS12215	COG1562	ergosterol biosynthetic process
EVJ50_RS12220	COG0724	RNA recognition motif
EVJ50_RS12225	COG0617	tRNA 3'-terminal CCA addition
EVJ50_RS12235	COG1214	PFAM Peptidase M22, glycoprotease
EVJ50_RS12245	COG0204	Acyl-transferase
EVJ50_RS12250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EVJ50_RS12255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EVJ50_RS12260	COG0416	fatty acid biosynthetic process
EVJ50_RS12270	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EVJ50_RS12275	COG3063	Type IV pilus biogenesis stability protein PilW
EVJ50_RS12280	COG2217	Heavy metal translocating P-type atpase
EVJ50_RS12285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EVJ50_RS12290	COG0470	DNA polymerase III
EVJ50_RS12295	COG0745	RESPONSE REGULATOR receiver
EVJ50_RS12305	COG1122	ATPase activity
EVJ50_RS12325	COG0463	Glycosyl transferase, family 2
EVJ50_RS12350	COG1215	transferase activity, transferring glycosyl groups
EVJ50_RS12360	COG3659	wide pore channel activity
EVJ50_RS12365	COG3659	wide pore channel activity
EVJ50_RS12380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVJ50_RS12385	COG0484	heat shock protein binding
EVJ50_RS12400	COG3263	regulation of cellular component size
EVJ50_RS12405	COG1090	epimerase
EVJ50_RS12425	COG0316	Belongs to the HesB IscA family
EVJ50_RS12430	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EVJ50_RS12440	COG1587	Uroporphyrinogen-III synthase
EVJ50_RS12445	COG0463	Glycosyl transferase, family 2
EVJ50_RS12445	COG0457	Tetratricopeptide repeat
EVJ50_RS12450	COG1472	Belongs to the glycosyl hydrolase 3 family
EVJ50_RS12455	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EVJ50_RS12480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EVJ50_RS12510	COG1032	radical SAM domain protein
EVJ50_RS12525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVJ50_RS12530	COG4243	Vitamin k epoxide reductase
EVJ50_RS12540	COG1555	photosystem II stabilization
EVJ50_RS12550	COG1968	undecaprenyl-diphosphatase activity
EVJ50_RS12570	COG0483	inositol monophosphate 1-phosphatase activity
EVJ50_RS12625	COG1570	exodeoxyribonuclease VII activity
EVJ50_RS12640	COG1643	Atp-dependent helicase
EVJ50_RS12655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVJ50_RS12670	COG0488	(ABC) transporter
EVJ50_RS12695	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EVJ50_RS12700	COG0569	domain protein
EVJ50_RS12705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EVJ50_RS12710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EVJ50_RS12720	COG0175	sulfate reduction
EVJ50_RS12725	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EVJ50_RS12730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVJ50_RS12750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVJ50_RS12755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVJ50_RS12765	COG0033	Phosphoglucomutase
EVJ50_RS12795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EVJ50_RS12820	COG0719	Fe-S assembly protein
EVJ50_RS12825	COG0396	ATPase activity
EVJ50_RS12830	COG0719	Fe-S assembly protein
EVJ50_RS12835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EVJ50_RS12845	COG0242	peptide deformylase activity
EVJ50_RS12860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EVJ50_RS12870	COG0537	adenosine 5'-monophosphoramidase activity
EVJ50_RS12875	COG4178	(ABC) transporter
EVJ50_RS12895	COG0515	serine threonine protein kinase
EVJ50_RS12925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVJ50_RS12935	COG1196	nuclear chromosome segregation
EVJ50_RS12950	COG0116	Belongs to the methyltransferase superfamily
EVJ50_RS12965	COG0523	cobalamin synthesis protein
EVJ50_RS12975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVJ50_RS12995	COG0523	cobalamin synthesis protein
EVJ50_RS13010	COG3588	fructose-bisphosphate aldolase
EVJ50_RS13105	COG0318	PFAM AMP-dependent synthetase and ligase
EVJ50_RS13110	COG4243	Vitamin k epoxide reductase
EVJ50_RS13125	COG0436	Aminotransferase
EVJ50_RS13135	COG0667	Aldo Keto reductase
EVJ50_RS13160	COG0737	Belongs to the 5'-nucleotidase family
EVJ50_RS13185	COG1741	Belongs to the pirin family
EVJ50_RS13195	COG1733	regulation of RNA biosynthetic process
EVJ50_RS13215	COG2720	vancomycin resistance protein
EVJ50_RS13225	COG0045	succinate-CoA ligase (ADP-forming) activity
EVJ50_RS13225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EVJ50_RS13225	COG1042	CoA-binding domain protein
EVJ50_RS13230	COG0123	including yeast histone deacetylase and acetoin utilization protein
EVJ50_RS13245	COG1034	ATP synthesis coupled electron transport
EVJ50_RS13250	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
EVJ50_RS13255	COG3259	Nickel-dependent hydrogenase
EVJ50_RS13290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EVJ50_RS13300	COG0298	carbon dioxide binding
EVJ50_RS13305	COG0674	pyruvate-flavodoxin oxidoreductase activity
EVJ50_RS13305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EVJ50_RS13305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EVJ50_RS13305	COG1013	pyruvate-flavodoxin oxidoreductase activity
EVJ50_RS13325	COG0484	heat shock protein binding
EVJ50_RS13330	COG0113	porphobilinogen synthase activity
EVJ50_RS13335	COG1193	negative regulation of DNA recombination
EVJ50_RS13340	COG3842	ATPase activity
EVJ50_RS13345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EVJ50_RS13365	COG0435	Glutathione S-transferase
EVJ50_RS13370	COG2988	succinylglutamate desuccinylase activity
EVJ50_RS13415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EVJ50_RS13425	COG0195	Participates in both transcription termination and antitermination
EVJ50_RS13430	COG0779	Required for maturation of 30S ribosomal subunits
EVJ50_RS13440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EVJ50_RS13445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVJ50_RS13450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EVJ50_RS13455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EVJ50_RS13460	COG0268	Binds directly to 16S ribosomal RNA
EVJ50_RS13465	COG0084	hydrolase, TatD family'
EVJ50_RS13475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVJ50_RS13480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVJ50_RS13490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EVJ50_RS13525	COG0357	Ribosomal RNA small subunit methyltransferase G
EVJ50_RS13530	COG0484	heat shock protein binding
EVJ50_RS13540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVJ50_RS13550	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EVJ50_RS13555	COG2226	methyltransferase
EVJ50_RS13565	COG0156	8-amino-7-oxononanoate synthase activity
EVJ50_RS13570	COG4581	dead DEAH box helicase
EVJ50_RS13575	COG0114	fumarate hydratase activity
EVJ50_RS13580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EVJ50_RS13595	COG0347	Belongs to the P(II) protein family
EVJ50_RS13610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EVJ50_RS13615	COG1333	cytochrome c biogenesis protein
EVJ50_RS13625	COG0772	Belongs to the SEDS family
EVJ50_RS13645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EVJ50_RS13650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EVJ50_RS13660	COG0356	it plays a direct role in the translocation of protons across the membrane
EVJ50_RS13665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVJ50_RS13670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EVJ50_RS13675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EVJ50_RS13680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EVJ50_RS13685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EVJ50_RS13690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EVJ50_RS13695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVJ50_RS13705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVJ50_RS13710	COG0659	secondary active sulfate transmembrane transporter activity
EVJ50_RS13715	COG0589	response to stress
EVJ50_RS13715	COG0475	glutathione-regulated potassium exporter activity
EVJ50_RS13720	COG1017	nitric oxide dioxygenase activity
EVJ50_RS13720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVJ50_RS13730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EVJ50_RS13730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVJ50_RS13735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EVJ50_RS13740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVJ50_RS13745	COG1253	flavin adenine dinucleotide binding
EVJ50_RS13750	COG0006	proline dipeptidase activity
EVJ50_RS13765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EVJ50_RS13770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EVJ50_RS13775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EVJ50_RS13780	COG0459	protein refolding
EVJ50_RS13795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EVJ50_RS13800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EVJ50_RS13810	COG0443	Heat shock 70 kDa protein
EVJ50_RS13840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EVJ50_RS13860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVJ50_RS13865	COG2264	protein methyltransferase activity
EVJ50_RS13875	COG2010	Cytochrome c
EVJ50_RS13880	COG1234	tRNA 3'-trailer cleavage
EVJ50_RS13885	COG2385	sporulation resulting in formation of a cellular spore
EVJ50_RS13890	COG0363	glucosamine-6-phosphate deaminase activity
EVJ50_RS13895	COG0217	transcriptional regulatory protein
EVJ50_RS13900	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EVJ50_RS13905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EVJ50_RS13910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EVJ50_RS13915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EVJ50_RS13920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EVJ50_RS13930	COG4251	negative regulation of phosphorylation
EVJ50_RS13935	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EVJ50_RS13940	COG5002	protein histidine kinase activity
EVJ50_RS13945	COG0151	Belongs to the GarS family
EVJ50_RS13955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EVJ50_RS13965	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EVJ50_RS13970	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EVJ50_RS13975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVJ50_RS13985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVJ50_RS14005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EVJ50_RS14020	COG4566	intracellular signal transduction
EVJ50_RS14030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EVJ50_RS14035	COG0284	orotidine-5'-phosphate decarboxylase activity
EVJ50_RS14040	COG0438	transferase activity, transferring glycosyl groups
EVJ50_RS14050	COG1381	Involved in DNA repair and RecF pathway recombination
EVJ50_RS14055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EVJ50_RS14060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EVJ50_RS14065	COG0321	lipoyl(octanoyl) transferase activity
EVJ50_RS14070	COG1022	Amp-dependent synthetase and ligase
EVJ50_RS14085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EVJ50_RS14090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EVJ50_RS14130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EVJ50_RS14160	COG1185	polyribonucleotide nucleotidyltransferase activity
EVJ50_RS14165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EVJ50_RS14170	COG0750	zinc metalloprotease
EVJ50_RS14175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EVJ50_RS14200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EVJ50_RS14205	COG0579	oxidoreductase
EVJ50_RS14210	COG0481	GTPase activity
EVJ50_RS14230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVJ50_RS14235	COG3695	enzyme binding
EVJ50_RS14240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EVJ50_RS14240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EVJ50_RS14245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EVJ50_RS14250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EVJ50_RS14260	COG0107	imidazoleglycerol-phosphate synthase activity
EVJ50_RS14270	COG2226	methyltransferase
EVJ50_RS14275	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EVJ50_RS14280	COG0752	glycyl-tRNA synthetase alpha subunit
EVJ50_RS14325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EVJ50_RS14330	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EVJ50_RS14340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVJ50_RS14345	COG0740	serine-type endopeptidase activity
EVJ50_RS14350	COG0740	serine-type endopeptidase activity
EVJ50_RS14355	COG4956	integral membrane protein (PIN domain superfamily)
EVJ50_RS14365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EVJ50_RS14375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EVJ50_RS14395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVJ50_RS14400	COG2066	Belongs to the glutaminase family
EVJ50_RS14400	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EVJ50_RS14405	COG4948	Mandelate Racemase Muconate Lactonizing