locus-tag	class	description
C7I86_RS00005	COG0142	geranyltranstransferase activity
C7I86_RS00010	COG1187	pseudouridine synthase activity
C7I86_RS00020	COG0515	serine threonine protein kinase
C7I86_RS00025	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_RS00030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_RS00035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C7I86_RS00045	COG1166	arginine decarboxylase activity
C7I86_RS00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_RS00060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7I86_RS00065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7I86_RS00070	COG1120	ATPase activity
C7I86_RS00075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_RS00085	COG4977	sequence-specific DNA binding
C7I86_RS00110	COG2207	Transcriptional regulator
C7I86_RS00115	COG2226	methyltransferase
C7I86_RS00125	COG0848	biopolymer transport protein
C7I86_RS00130	COG0811	peptide transport
C7I86_RS00145	COG1132	(ABC) transporter
C7I86_RS00160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_RS00165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7I86_RS00175	COG1132	(ABC) transporter
C7I86_RS00225	COG0409	Hydrogenase expression formation protein
C7I86_RS00230	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7I86_RS00235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7I86_RS00240	COG0297	glycogen (starch) synthase activity
C7I86_RS00255	COG1131	(ABC) transporter
C7I86_RS00270	COG2318	DinB family
C7I86_RS00275	COG4106	trans-aconitate 2-methyltransferase activity
C7I86_RS00290	COG1214	PFAM Peptidase M22, glycoprotease
C7I86_RS00310	COG1615	UPF0182 protein
C7I86_RS00325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7I86_RS00330	COG0563	adenylate kinase activity
C7I86_RS00335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7I86_RS00355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7I86_RS00370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7I86_RS00375	COG0194	GDP metabolic process
C7I86_RS00380	COG0406	alpha-ribazole phosphatase activity
C7I86_RS00390	COG0730	response to heat
C7I86_RS00395	COG1413	lyase activity
C7I86_RS00410	COG0330	HflC and HflK could
C7I86_RS00415	COG1530	ribonuclease E activity
C7I86_RS00420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7I86_RS00425	COG0494	nUDIX hydrolase
C7I86_RS00430	COG1185	polyribonucleotide nucleotidyltransferase activity
C7I86_RS00435	COG0681	Belongs to the peptidase S26 family
C7I86_RS00450	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7I86_RS00460	COG1401	restriction endodeoxyribonuclease activity
C7I86_RS00470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7I86_RS00475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7I86_RS00520	COG1104	cysteine desulfurase activity
C7I86_RS00545	COG0582	viral genome integration into host DNA
C7I86_RS00555	COG2022	thiamine diphosphate biosynthetic process
C7I86_RS00555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_RS00565	COG5002	protein histidine kinase activity
C7I86_RS00575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7I86_RS00595	COG0704	Plays a role in the regulation of phosphate uptake
C7I86_RS00600	COG0779	Required for maturation of 30S ribosomal subunits
C7I86_RS00605	COG0195	Participates in both transcription termination and antitermination
C7I86_RS00615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7I86_RS00655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7I86_RS00665	COG0011	TIGRFAM Protein of
C7I86_RS00675	COG0589	response to stress
C7I86_RS00685	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7I86_RS00690	COG0010	Belongs to the arginase family
C7I86_RS00695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_RS00735	COG2099	Precorrin-6x reductase
C7I86_RS00750	COG1007	ATP synthesis coupled electron transport
C7I86_RS00770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7I86_RS00775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7I86_RS00780	COG0426	domain, Protein
C7I86_RS00780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_RS00790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_RS00790	COG0426	domain, Protein
C7I86_RS00800	COG0793	Belongs to the peptidase S41A family
C7I86_RS00805	COG0009	L-threonylcarbamoyladenylate synthase
C7I86_RS00810	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
C7I86_RS00815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7I86_RS00820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7I86_RS00825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7I86_RS00830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7I86_RS00835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7I86_RS00840	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7I86_RS00845	COG0356	it plays a direct role in the translocation of protons across the membrane
C7I86_RS00855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_RS00870	COG0714	Associated with various cellular activities
C7I86_RS00875	COG0316	Belongs to the HesB IscA family
C7I86_RS00880	COG0697	spore germination
C7I86_RS00890	COG1127	ABC transporter
C7I86_RS00900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7I86_RS00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7I86_RS00940	COG0163	prenyltransferase activity
C7I86_RS00950	COG0589	response to stress
C7I86_RS00960	COG1716	ATPase activity
C7I86_RS00960	COG5001	Diguanylate cyclase
C7I86_RS00970	COG1217	gtp-binding protein TYPA
C7I86_RS00985	COG1234	tRNA 3'-trailer cleavage
C7I86_RS00995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7I86_RS01010	COG0631	protein serine/threonine phosphatase activity
C7I86_RS01015	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7I86_RS01025	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C7I86_RS01030	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS01035	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS01040	COG0493	'glutamate synthase
C7I86_RS01085	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_RS01085	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_RS01100	COG1982	Orn Lys Arg decarboxylase major
C7I86_RS01105	COG0686	Belongs to the AlaDH PNT family
C7I86_RS01110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7I86_RS01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_RS01140	COG0673	inositol 2-dehydrogenase activity
C7I86_RS01145	COG0700	Nucleoside recognition
C7I86_RS01150	COG2715	membrane protein required for spore maturation
C7I86_RS01155	COG1640	4-alpha-glucanotransferase
C7I86_RS01165	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7I86_RS01180	COG3706	GGDEF domain
C7I86_RS01180	COG4251	negative regulation of phosphorylation
C7I86_RS01180	COG5001	Diguanylate cyclase
C7I86_RS01180	COG2203	Gaf domain
C7I86_RS01185	COG2205	protein histidine kinase activity
C7I86_RS01185	COG0784	Response regulator, receiver
C7I86_RS01200	COG1981	membrane
C7I86_RS01205	COG0175	sulfate reduction
C7I86_RS01210	COG1420	regulation of RNA biosynthetic process
C7I86_RS01220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7I86_RS01225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7I86_RS01235	COG0003	Pfam Anion-transporting ATPase
C7I86_RS01240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7I86_RS01255	COG0484	heat shock protein binding
C7I86_RS01260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7I86_RS01270	COG1216	Glycosyl transferase, family 2
C7I86_RS01270	COG0463	Glycosyl transferase, family 2
C7I86_RS01280	COG0077	Prephenate dehydratase
C7I86_RS01280	COG1605	Chorismate mutase
C7I86_RS01290	COG2203	Gaf domain
C7I86_RS01290	COG3706	GGDEF domain
C7I86_RS01290	COG4251	negative regulation of phosphorylation
C7I86_RS01290	COG5001	Diguanylate cyclase
C7I86_RS01305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C7I86_RS01335	COG0589	response to stress
C7I86_RS01340	COG2226	methyltransferase
C7I86_RS01355	COG0538	isocitrate dehydrogenase activity
C7I86_RS01360	COG4636	protein conserved in cyanobacteria
C7I86_RS01370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS01385	COG0762	integral membrane protein
C7I86_RS01390	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_RS01395	COG0336	Belongs to the RNA methyltransferase TrmD family
C7I86_RS01400	COG0205	6-phosphofructokinase activity
C7I86_RS01405	COG1289	transmembrane transporter activity
C7I86_RS01410	COG1555	photosystem II stabilization
C7I86_RS01420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7I86_RS01425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7I86_RS01430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7I86_RS01455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7I86_RS01460	COG0277	FAD linked oxidase domain protein
C7I86_RS01480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7I86_RS01490	COG0408	coproporphyrinogen oxidase activity
C7I86_RS01495	COG5398	heme oxygenase
C7I86_RS01505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7I86_RS01525	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7I86_RS01530	COG0672	)-iron permease
C7I86_RS01535	COG0592	DNA-directed DNA polymerase activity
C7I86_RS01540	COG0159	tryptophan synthase activity
C7I86_RS01555	COG0436	Aminotransferase
C7I86_RS01565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7I86_RS01580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7I86_RS01590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7I86_RS01595	COG0701	Predicted permease
C7I86_RS01615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7I86_RS01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7I86_RS01625	COG4636	protein conserved in cyanobacteria
C7I86_RS01630	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7I86_RS01650	COG0489	protein tyrosine kinase activity
C7I86_RS01650	COG3206	protein involved in exopolysaccharide biosynthesis
C7I86_RS01690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_RS01735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7I86_RS01740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7I86_RS01745	COG1088	dTDP-glucose 4,6-dehydratase activity
C7I86_RS01750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_RS01775	COG1215	transferase activity, transferring glycosyl groups
C7I86_RS01785	COG1215	transferase activity, transferring glycosyl groups
C7I86_RS01790	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS01815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_RS01840	COG0297	glycogen (starch) synthase activity
C7I86_RS01845	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS01850	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_RS01860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_RS01895	COG0110	maltose O-acetyltransferase activity
C7I86_RS01910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_RS01920	COG3781	membrane
C7I86_RS01925	COG0045	succinate-CoA ligase (ADP-forming) activity
C7I86_RS01930	COG0861	Integral membrane protein TerC family
C7I86_RS01935	COG2268	Band 7 protein
C7I86_RS01940	COG0463	Glycosyl transferase, family 2
C7I86_RS01945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7I86_RS01955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7I86_RS01960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7I86_RS01965	COG0004	ammonium transporteR
C7I86_RS01970	COG0745	RESPONSE REGULATOR receiver
C7I86_RS01985	COG0737	Belongs to the 5'-nucleotidase family
C7I86_RS01995	COG0529	Catalyzes the synthesis of activated sulfate
C7I86_RS02000	COG0811	peptide transport
C7I86_RS02005	COG0848	biopolymer transport protein
C7I86_RS02010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7I86_RS02010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7I86_RS02015	COG0530	calcium, potassium:sodium antiporter activity
C7I86_RS02020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7I86_RS02030	COG0745	RESPONSE REGULATOR receiver
C7I86_RS02035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7I86_RS02040	COG1234	tRNA 3'-trailer cleavage
C7I86_RS02065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7I86_RS02070	COG2203	Gaf domain
C7I86_RS02070	COG3706	GGDEF domain
C7I86_RS02070	COG4251	negative regulation of phosphorylation
C7I86_RS02070	COG5001	Diguanylate cyclase
C7I86_RS02080	COG0471	metal ion transport
C7I86_RS02080	COG3273	potassium ion transport
C7I86_RS02110	COG3854	ATPases associated with a variety of cellular activities
C7I86_RS02115	COG0352	thiamine-phosphate diphosphorylase activity
C7I86_RS02120	COG0434	BtpA family
C7I86_RS02145	COG0564	pseudouridine synthase activity
C7I86_RS02150	COG5001	Diguanylate cyclase
C7I86_RS02150	COG4251	negative regulation of phosphorylation
C7I86_RS02150	COG3706	GGDEF domain
C7I86_RS02150	COG2203	Gaf domain
C7I86_RS02160	COG0475	glutathione-regulated potassium exporter activity
C7I86_RS02195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7I86_RS02200	COG1733	regulation of RNA biosynthetic process
C7I86_RS02205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7I86_RS02245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7I86_RS02260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_RS02270	COG1487	ribonuclease activity
C7I86_RS02290	COG2361	Protein of unknown function DUF86
C7I86_RS02305	COG0067	glutamate synthase
C7I86_RS02305	COG0069	glutamate synthase activity
C7I86_RS02305	COG0070	glutamate synthase
C7I86_RS02315	COG2133	pyrroloquinoline quinone binding
C7I86_RS02320	COG1797	cobyrinic acid a,c-diamide synthase activity
C7I86_RS02325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C7I86_RS02330	COG1022	Amp-dependent synthetase and ligase
C7I86_RS02335	COG0784	Response regulator, receiver
C7I86_RS02350	COG0840	transmembrane signaling receptor activity
C7I86_RS02350	COG2203	Gaf domain
C7I86_RS02355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7I86_RS02360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7I86_RS02365	COG5001	Diguanylate cyclase
C7I86_RS02365	COG4251	negative regulation of phosphorylation
C7I86_RS02365	COG3706	GGDEF domain
C7I86_RS02365	COG2203	Gaf domain
C7I86_RS02370	COG0419	ATPase involved in DNA repair
C7I86_RS02375	COG0484	heat shock protein binding
C7I86_RS02380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7I86_RS02390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7I86_RS02415	COG1429	ligase activity, forming nitrogen-metal bonds
C7I86_RS02430	COG3956	TIGRFAM MazG family protein
C7I86_RS02440	COG5002	protein histidine kinase activity
C7I86_RS02460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_RS02475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7I86_RS02480	COG1247	-acetyltransferase
C7I86_RS02485	COG0174	glutamine synthetase
C7I86_RS02495	COG2203	Gaf domain
C7I86_RS02495	COG3706	GGDEF domain
C7I86_RS02495	COG4251	negative regulation of phosphorylation
C7I86_RS02495	COG5001	Diguanylate cyclase
C7I86_RS02505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7I86_RS02510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7I86_RS02525	COG2310	stress, protein
C7I86_RS02530	COG0076	glutamate decarboxylase activity
C7I86_RS02545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_RS02550	COG0829	nickel cation binding
C7I86_RS02565	COG1045	serine acetyltransferase
C7I86_RS02580	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C7I86_RS02595	COG0271	Belongs to the BolA IbaG family
C7I86_RS02600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7I86_RS02605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7I86_RS02610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7I86_RS02615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7I86_RS02625	COG0804	urea catabolic process
C7I86_RS02640	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS02660	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7I86_RS02665	COG1773	rubredoxin
C7I86_RS02670	COG4447	cellulose binding
C7I86_RS02695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7I86_RS02705	COG3385	transposase activity
C7I86_RS02725	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7I86_RS02735	COG3228	Belongs to the MtfA family
C7I86_RS02770	COG1121	(ABC) transporter
C7I86_RS02775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7I86_RS02790	COG1702	phosphate starvation-inducible protein PhoH
C7I86_RS02805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_RS02825	COG0484	heat shock protein binding
C7I86_RS02830	COG0443	Heat shock 70 kDa protein
C7I86_RS02835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7I86_RS02875	COG3659	wide pore channel activity
C7I86_RS02885	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7I86_RS02885	COG2247	cell wall binding repeat
C7I86_RS02945	COG0768	penicillin binding
C7I86_RS02955	COG0247	lactate metabolic process
C7I86_RS02965	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_RS02975	COG0583	DNA-binding transcription factor activity
C7I86_RS02985	COG0384	phenazine biosynthesis protein PhzF
C7I86_RS02995	COG2319	Wd-40 repeat
C7I86_RS03000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_RS03025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7I86_RS03025	COG0475	glutathione-regulated potassium exporter activity
C7I86_RS03030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7I86_RS03050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C7I86_RS03055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C7I86_RS03070	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
C7I86_RS03075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7I86_RS03090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7I86_RS03095	COG0629	single-stranded DNA binding
C7I86_RS03110	COG0668	transmembrane transport
C7I86_RS03120	COG0745	RESPONSE REGULATOR receiver
C7I86_RS03125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_RS03125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C7I86_RS03130	COG3937	granule-associated protein
C7I86_RS03145	COG2226	methyltransferase
C7I86_RS03155	COG0681	Belongs to the peptidase S26 family
C7I86_RS03165	COG1271	oxidase subunit
C7I86_RS03170	COG1294	oxidase, subunit
C7I86_RS03175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7I86_RS03180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7I86_RS03185	COG0412	Dienelactone hydrolase
C7I86_RS03230	COG2198	Histidine kinase
C7I86_RS03230	COG0643	Histidine kinase
C7I86_RS03230	COG0784	Response regulator, receiver
C7I86_RS03235	COG0840	transmembrane signaling receptor activity
C7I86_RS03235	COG2203	Gaf domain
C7I86_RS03250	COG0784	Response regulator, receiver
C7I86_RS03255	COG0557	exoribonuclease II activity
C7I86_RS03265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_RS03280	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7I86_RS03290	COG5002	protein histidine kinase activity
C7I86_RS03295	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7I86_RS03305	COG1309	transcriptional regulator
C7I86_RS03330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
C7I86_RS03340	COG2385	sporulation resulting in formation of a cellular spore
C7I86_RS03350	COG3411	Ferredoxin
C7I86_RS03355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_RS03380	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7I86_RS03385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7I86_RS03390	COG0237	dephospho-CoA kinase activity
C7I86_RS03395	COG0237	dephospho-CoA kinase activity
C7I86_RS03425	COG0515	serine threonine protein kinase
C7I86_RS03430	COG0515	serine threonine protein kinase
C7I86_RS03440	COG2988	succinylglutamate desuccinylase activity
C7I86_RS03445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_RS03455	COG0739	heme binding
C7I86_RS03460	COG0587	DNA-directed DNA polymerase activity
C7I86_RS03475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7I86_RS03505	COG1006	Multisubunit Na H antiporter MnhC subunit
C7I86_RS03510	COG0651	ATP synthesis coupled electron transport
C7I86_RS03515	COG1006	Multisubunit Na H antiporter MnhC subunit
C7I86_RS03580	COG1132	(ABC) transporter
C7I86_RS03585	COG3063	Type IV pilus biogenesis stability protein PilW
C7I86_RS03590	COG2217	Heavy metal translocating P-type atpase
C7I86_RS03595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7I86_RS03600	COG0745	RESPONSE REGULATOR receiver
C7I86_RS03610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7I86_RS03615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7I86_RS03625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7I86_RS03655	COG0557	exoribonuclease II activity
C7I86_RS03665	COG2208	phosphoserine phosphatase activity
C7I86_RS03675	COG0165	Argininosuccinate lyase
C7I86_RS03680	COG2816	NAD+ diphosphatase activity
C7I86_RS03695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7I86_RS03700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7I86_RS03705	COG1845	cytochrome c oxidase, subunit III
C7I86_RS03710	COG3118	belongs to the thioredoxin family
C7I86_RS03720	COG1116	anion transmembrane transporter activity
C7I86_RS03725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_RS03740	COG0375	protein maturation
C7I86_RS03745	COG0010	Belongs to the arginase family
C7I86_RS03760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_RS03770	COG0495	leucyl-tRNA aminoacylation
C7I86_RS03775	COG0786	glutamate:sodium symporter activity
C7I86_RS03785	COG2205	protein histidine kinase activity
C7I86_RS03795	COG1132	(ABC) transporter
C7I86_RS03815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7I86_RS03820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7I86_RS03825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7I86_RS03850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7I86_RS03855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7I86_RS03865	COG0254	rRNA binding
C7I86_RS03870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7I86_RS03875	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7I86_RS03880	COG0101	tRNA pseudouridine synthase activity
C7I86_RS03885	COG0203	ribosomal protein L17
C7I86_RS03890	COG0202	RNA polymerase activity
C7I86_RS03895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7I86_RS03900	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7I86_RS03905	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7I86_RS03910	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7I86_RS03915	COG0563	adenylate kinase activity
C7I86_RS03920	COG0201	protein transport
C7I86_RS03925	COG0200	Binds to the 23S rRNA
C7I86_RS03930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7I86_RS03935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7I86_RS03940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7I86_RS03945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7I86_RS03950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7I86_RS03955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7I86_RS03960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7I86_RS03965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7I86_RS03970	COG0255	Belongs to the universal ribosomal protein uL29 family
C7I86_RS03975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7I86_RS03980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7I86_RS03985	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7I86_RS03990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7I86_RS03995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7I86_RS04000	COG0089	rRNA binding
C7I86_RS04005	COG0088	Forms part of the polypeptide exit tunnel
C7I86_RS04010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7I86_RS04015	COG0783	Belongs to the Dps family
C7I86_RS04035	COG2010	Cytochrome c
C7I86_RS04045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7I86_RS04050	COG0830	nickel cation binding
C7I86_RS04060	COG1131	(ABC) transporter
C7I86_RS04075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7I86_RS04080	COG0085	RNA polymerase activity
C7I86_RS04085	COG0084	hydrolase, TatD family'
C7I86_RS04090	COG0268	Binds directly to 16S ribosomal RNA
C7I86_RS04095	COG5002	protein histidine kinase activity
C7I86_RS04105	COG0210	DNA helicase
C7I86_RS04105	COG0210	DNA helicase
C7I86_RS04110	COG1196	nuclear chromosome segregation
C7I86_RS04115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7I86_RS04135	COG0758	DNA mediated transformation
C7I86_RS04135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7I86_RS04140	COG0393	Putative heavy-metal-binding
C7I86_RS04150	COG0450	alkyl hydroperoxide reductase
C7I86_RS04155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7I86_RS04170	COG1175	transmembrane transport
C7I86_RS04180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_RS04205	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS04205	COG3347	Dehydrogenase
C7I86_RS04225	COG3706	GGDEF domain
C7I86_RS04225	COG2203	Gaf domain
C7I86_RS04225	COG5001	Diguanylate cyclase
C7I86_RS04225	COG4251	negative regulation of phosphorylation
C7I86_RS04230	COG0745	RESPONSE REGULATOR receiver
C7I86_RS04235	COG0784	Response regulator, receiver
C7I86_RS04245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7I86_RS04250	COG2239	Acts as a magnesium transporter
C7I86_RS04280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7I86_RS04285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7I86_RS04290	COG1799	cell septum assembly
C7I86_RS04295	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C7I86_RS04295	COG0662	Cupin 2, conserved barrel domain protein
C7I86_RS04310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7I86_RS04315	COG0459	protein refolding
C7I86_RS04335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7I86_RS04340	COG0222	ribosome binding
C7I86_RS04345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7I86_RS04350	COG0081	regulation of translation
C7I86_RS04355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7I86_RS04360	COG0250	Participates in transcription elongation, termination and antitermination
C7I86_RS04365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7I86_RS04375	COG0335	large ribosomal subunit rRNA binding
C7I86_RS04405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_RS04415	COG3243	poly(R)-hydroxyalkanoic acid synthase
C7I86_RS04425	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C7I86_RS04435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS04440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_RS04450	COG2885	chlorophyll binding
C7I86_RS04455	COG2885	chlorophyll binding
C7I86_RS04465	COG1132	(ABC) transporter
C7I86_RS04475	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS04485	COG0745	RESPONSE REGULATOR receiver
C7I86_RS04490	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7I86_RS04490	COG0022	dehydrogenase e1 component
C7I86_RS04495	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS04500	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS04505	COG1929	Belongs to the glycerate kinase type-1 family
C7I86_RS04510	COG3659	wide pore channel activity
C7I86_RS04515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7I86_RS04520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7I86_RS04525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7I86_RS04565	COG0776	regulation of translation
C7I86_RS04580	COG0514	ATP-dependent DNA helicase (RecQ)
C7I86_RS04590	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
C7I86_RS04595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7I86_RS04605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7I86_RS04655	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS04660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7I86_RS04665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7I86_RS04670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_RS04685	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7I86_RS04690	COG0242	peptide deformylase activity
C7I86_RS04700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7I86_RS04730	COG0243	molybdopterin cofactor binding
C7I86_RS04740	COG1116	anion transmembrane transporter activity
C7I86_RS04745	COG1116	anion transmembrane transporter activity
C7I86_RS04745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_RS04750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_RS04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_RS04760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7I86_RS04770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7I86_RS04775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7I86_RS04785	COG0793	Belongs to the peptidase S41A family
C7I86_RS04795	COG0275	rRNA processing
C7I86_RS04805	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C7I86_RS04830	COG1090	epimerase
C7I86_RS04835	COG3842	ATPase activity
C7I86_RS04840	COG0515	serine threonine protein kinase
C7I86_RS04850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7I86_RS04855	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7I86_RS04860	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7I86_RS04865	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_RS04870	COG0589	response to stress
C7I86_RS04875	COG1233	COG1233 Phytoene dehydrogenase and related
C7I86_RS04890	COG1053	succinate dehydrogenase
C7I86_RS04895	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_RS04900	COG0537	adenosine 5'-monophosphoramidase activity
C7I86_RS04930	COG0402	S-adenosylhomocysteine deaminase activity
C7I86_RS04945	COG2267	carboxylic ester hydrolase activity
C7I86_RS04955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7I86_RS04960	COG0189	ligase activity
C7I86_RS04970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7I86_RS04975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7I86_RS05000	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C7I86_RS05005	COG0312	modulator of DNA gyrase
C7I86_RS05025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7I86_RS05035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7I86_RS05035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7I86_RS05050	COG2140	Oxalate decarboxylase
C7I86_RS05055	COG0058	SHG alpha-glucan phosphorylase activity
C7I86_RS05085	COG0515	serine threonine protein kinase
C7I86_RS05105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7I86_RS05105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7I86_RS05110	COG3437	response regulator, receiver
C7I86_RS05110	COG4999	Histidine kinase
C7I86_RS05110	COG3850	Histidine kinase
C7I86_RS05110	COG2205	protein histidine kinase activity
C7I86_RS05145	COG0546	phosphoglycolate phosphatase activity
C7I86_RS05150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7I86_RS05155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7I86_RS05170	COG0501	Belongs to the peptidase M48B family
C7I86_RS05175	COG0539	negative regulation of cytoplasmic translation
C7I86_RS05185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7I86_RS05190	COG1132	(ABC) transporter
C7I86_RS05195	COG0469	pyruvate kinase activity
C7I86_RS05215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7I86_RS05220	COG1268	BioY protein
C7I86_RS05225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7I86_RS05245	COG3659	wide pore channel activity
C7I86_RS05250	COG0765	amino acid transport
C7I86_RS05260	COG0058	SHG alpha-glucan phosphorylase activity
C7I86_RS05270	COG0575	Belongs to the CDS family
C7I86_RS05295	COG1970	mechanosensitive ion channel activity
C7I86_RS05300	COG0632	four-way junction helicase activity
C7I86_RS05305	COG1836	PFAM Integral membrane protein DUF92
C7I86_RS05310	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7I86_RS05315	COG0724	RNA recognition motif
C7I86_RS05320	COG0154	amidase activity
C7I86_RS05325	COG0739	heme binding
C7I86_RS05330	COG0509	glycine decarboxylation via glycine cleavage system
C7I86_RS05345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7I86_RS05365	COG1316	TRANSCRIPTIONal
C7I86_RS05380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7I86_RS05395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7I86_RS05400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7I86_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS05430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_RS05445	COG0322	excinuclease ABC activity
C7I86_RS05470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7I86_RS05480	COG3258	Cytochrome c
C7I86_RS05485	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_RS05510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7I86_RS05535	COG2319	Wd-40 repeat
C7I86_RS05540	COG2319	Wd-40 repeat
C7I86_RS05560	COG1082	Xylose isomerase domain protein TIM barrel
C7I86_RS05575	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7I86_RS05600	COG1366	Belongs to the anti-sigma-factor antagonist family
C7I86_RS05615	COG2770	Histidine kinase
C7I86_RS05615	COG2208	phosphoserine phosphatase activity
C7I86_RS05645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7I86_RS05650	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7I86_RS05690	COG1741	Belongs to the pirin family
C7I86_RS05700	COG1193	negative regulation of DNA recombination
C7I86_RS05705	COG0631	protein serine/threonine phosphatase activity
C7I86_RS05710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_RS05720	COG3937	granule-associated protein
C7I86_RS05735	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7I86_RS05740	COG3932	Exopolysaccharide synthesis, ExoD
C7I86_RS05745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7I86_RS05755	COG0360	Binds together with S18 to 16S ribosomal RNA
C7I86_RS05760	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7I86_RS05765	COG1413	lyase activity
C7I86_RS05770	COG0641	radical SAM
C7I86_RS05805	COG0083	homoserine kinase activity
C7I86_RS05815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7I86_RS05820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS05830	COG0196	riboflavin kinase activity
C7I86_RS05850	COG0180	Tryptophanyl-tRNA synthetase
C7I86_RS05855	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7I86_RS05860	COG0799	negative regulation of ribosome biogenesis
C7I86_RS05870	COG0181	hydroxymethylbilane synthase activity
C7I86_RS05875	COG0427	acetyl-CoA hydrolase
C7I86_RS05880	COG0280	phosphate acetyltransferase
C7I86_RS05880	COG0857	belongs to the CobB CobQ family
C7I86_RS05890	COG1489	DNA binding
C7I86_RS05900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_RS05910	COG0602	queuosine metabolic process
C7I86_RS05915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7I86_RS05920	COG0612	Peptidase, M16
C7I86_RS05925	COG0612	Peptidase, M16
C7I86_RS05935	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7I86_RS05950	COG1372	Participates in initiation and elongation during chromosome replication
C7I86_RS05950	COG0187	DNA topoisomerase II activity
C7I86_RS05965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7I86_RS05965	COG0646	methionine synthase
C7I86_RS05975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7I86_RS06000	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS06010	COG2197	response regulator
C7I86_RS06015	COG4251	negative regulation of phosphorylation
C7I86_RS06015	COG3706	GGDEF domain
C7I86_RS06015	COG5001	Diguanylate cyclase
C7I86_RS06015	COG2203	Gaf domain
C7I86_RS06025	COG0616	signal peptide processing
C7I86_RS06035	COG0596	Alpha beta hydrolase
C7I86_RS06040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7I86_RS06050	COG0747	negative chemotaxis
C7I86_RS06060	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7I86_RS06100	COG4968	Prepilin-type N-terminal cleavage methylation domain
C7I86_RS06105	COG4968	Prepilin-type N-terminal cleavage methylation domain
C7I86_RS06130	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS06135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_RS06140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7I86_RS06150	COG2199	diguanylate cyclase activity
C7I86_RS06155	COG0750	zinc metalloprotease
C7I86_RS06160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7I86_RS06170	COG0590	tRNA wobble adenosine to inosine editing
C7I86_RS06180	COG0415	Belongs to the DNA photolyase family
C7I86_RS06190	COG3409	Peptidoglycan-binding domain 1 protein
C7I86_RS06190	COG3429	Glucose-6-phosphate dehydrogenase subunit
C7I86_RS06200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7I86_RS06205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7I86_RS06220	COG1122	ATPase activity
C7I86_RS06225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_RS06235	COG0678	peroxiredoxin activity
C7I86_RS06275	COG1252	NADH dehydrogenase
C7I86_RS06285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7I86_RS06310	COG0415	Belongs to the DNA photolyase family
C7I86_RS06325	COG1595	DNA-templated transcription, initiation
C7I86_RS06365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7I86_RS06375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7I86_RS06380	COG3339	Conserved Protein
C7I86_RS06390	COG0312	modulator of DNA gyrase
C7I86_RS06395	COG0482	sulfurtransferase activity
C7I86_RS06410	COG0488	(ABC) transporter
C7I86_RS06415	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
C7I86_RS06425	COG0284	orotidine-5'-phosphate decarboxylase activity
C7I86_RS06475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7I86_RS06485	COG0697	spore germination
C7I86_RS06520	COG0583	DNA-binding transcription factor activity
C7I86_RS06540	COG2814	Major facilitator Superfamily
C7I86_RS06545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7I86_RS06550	COG0573	inorganic phosphate transmembrane transporter activity
C7I86_RS06555	COG0581	inorganic phosphate transmembrane transporter activity
C7I86_RS06560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_RS06565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_RS06570	COG2154	pterin-4-alpha-carbinolamine dehydratase
C7I86_RS06595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7I86_RS06595	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_RS06600	COG1562	ergosterol biosynthetic process
C7I86_RS06605	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C7I86_RS06610	COG0831	urea catabolic process
C7I86_RS06620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7I86_RS06640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7I86_RS06645	COG0730	response to heat
C7I86_RS06655	COG2188	Transcriptional regulator
C7I86_RS06670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7I86_RS06675	COG0640	Transcriptional regulator
C7I86_RS06680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7I86_RS06685	COG1754	DNA topoisomerase type I activity
C7I86_RS06685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7I86_RS06725	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
C7I86_RS06755	COG2264	protein methyltransferase activity
C7I86_RS06760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7I86_RS06775	COG0386	Belongs to the glutathione peroxidase family
C7I86_RS06780	COG0183	Belongs to the thiolase family
C7I86_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS06795	COG2205	protein histidine kinase activity
C7I86_RS06795	COG3850	Histidine kinase
C7I86_RS06795	COG3437	response regulator, receiver
C7I86_RS06795	COG4999	Histidine kinase
C7I86_RS06815	COG4242	Belongs to the peptidase S51 family
C7I86_RS06820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7I86_RS06820	COG0189	ligase activity
C7I86_RS06855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_RS06860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_RS06870	COG0285	dihydrofolate synthase activity
C7I86_RS06885	COG4636	protein conserved in cyanobacteria
C7I86_RS06905	COG1606	tRNA processing
C7I86_RS06915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7I86_RS06925	COG2045	Belongs to the ComB family
C7I86_RS06930	COG0778	Nitroreductase
C7I86_RS06935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7I86_RS06945	COG0516	GMP reductase activity
C7I86_RS06950	COG0395	ABC-type sugar transport system, permease component
C7I86_RS06955	COG3268	Saccharopine dehydrogenase
C7I86_RS06970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7I86_RS06975	COG1121	(ABC) transporter
C7I86_RS06980	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7I86_RS06990	COG4251	negative regulation of phosphorylation
C7I86_RS06995	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_RS07005	COG0583	DNA-binding transcription factor activity
C7I86_RS07010	COG0025	NhaP-type Na H and K H
C7I86_RS07015	COG2197	response regulator
C7I86_RS07020	COG5002	protein histidine kinase activity
C7I86_RS07025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7I86_RS07030	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7I86_RS07040	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C7I86_RS07045	COG2205	protein histidine kinase activity
C7I86_RS07055	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_RS07075	COG2385	sporulation resulting in formation of a cellular spore
C7I86_RS07080	COG0649	NAD binding
C7I86_RS07095	COG0429	hydrolase of the alpha beta-hydrolase fold
C7I86_RS07105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7I86_RS07110	COG3536	Protein conserved in bacteria
C7I86_RS07115	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7I86_RS07120	COG0716	FMN binding
C7I86_RS07130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7I86_RS07135	COG0012	GTP binding
C7I86_RS07140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_RS07195	COG3842	ATPase activity
C7I86_RS07205	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_RS07210	COG0222	ribosome binding
C7I86_RS07220	COG2066	Belongs to the glutaminase family
C7I86_RS07240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7I86_RS07255	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7I86_RS07260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7I86_RS07265	COG1333	cytochrome c biogenesis protein
C7I86_RS07275	COG1657	PFAM Prenyltransferase squalene oxidase
C7I86_RS07320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7I86_RS07330	COG1494	fructose-1,6-bisphosphatase
C7I86_RS07340	COG2346	COG2346, Truncated hemoglobins
C7I86_RS07345	COG3850	Histidine kinase
C7I86_RS07345	COG2205	protein histidine kinase activity
C7I86_RS07345	COG4999	Histidine kinase
C7I86_RS07345	COG3437	response regulator, receiver
C7I86_RS07355	COG3437	response regulator, receiver
C7I86_RS07360	COG1917	Cupin 2, conserved barrel domain protein
C7I86_RS07365	COG0552	protein localization to endoplasmic reticulum
C7I86_RS07375	COG0784	Response regulator, receiver
C7I86_RS07375	COG5002	protein histidine kinase activity
C7I86_RS07375	COG2205	protein histidine kinase activity
C7I86_RS07380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7I86_RS07390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7I86_RS07410	COG0667	Aldo Keto reductase
C7I86_RS07415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7I86_RS07425	COG0442	prolyl-tRNA aminoacylation
C7I86_RS07435	COG4372	Transposase
C7I86_RS07440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_RS07465	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS07470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7I86_RS07475	COG0416	fatty acid biosynthetic process
C7I86_RS07480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7I86_RS07500	COG0347	Belongs to the P(II) protein family
C7I86_RS07505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7I86_RS07530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7I86_RS07535	COG0473	3-isopropylmalate dehydrogenase activity
C7I86_RS07545	COG1575	Belongs to the MenA family. Type 1 subfamily
C7I86_RS07555	COG0656	L-ascorbic acid biosynthetic process
C7I86_RS07560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7I86_RS07595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7I86_RS07610	COG2161	toxin-antitoxin pair type II binding
C7I86_RS07615	COG4115	mRNA cleavage
C7I86_RS07650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7I86_RS07650	COG0517	IMP dehydrogenase activity
C7I86_RS07660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7I86_RS07670	COG1215	transferase activity, transferring glycosyl groups
C7I86_RS07695	COG1216	Glycosyl transferase, family 2
C7I86_RS07700	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C7I86_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS07740	COG0463	Glycosyl transferase, family 2
C7I86_RS07745	COG0113	porphobilinogen synthase activity
C7I86_RS07755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7I86_RS07760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7I86_RS07790	COG0312	modulator of DNA gyrase
C7I86_RS07795	COG2890	protein-(glutamine-N5) methyltransferase activity
C7I86_RS07800	COG2205	protein histidine kinase activity
C7I86_RS07815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7I86_RS07820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C7I86_RS07845	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7I86_RS07855	COG2205	protein histidine kinase activity
C7I86_RS07860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7I86_RS07865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7I86_RS07870	COG0612	Peptidase, M16
C7I86_RS07875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7I86_RS07880	COG3259	Nickel-dependent hydrogenase
C7I86_RS07895	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
C7I86_RS07900	COG1034	ATP synthesis coupled electron transport
C7I86_RS07945	COG0702	epimerase
C7I86_RS07980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7I86_RS07985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7I86_RS08000	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7I86_RS08010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7I86_RS08015	COG0673	inositol 2-dehydrogenase activity
C7I86_RS08030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7I86_RS08035	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7I86_RS08070	COG0095	Lipoate-protein ligase
C7I86_RS08090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C7I86_RS08100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7I86_RS08110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7I86_RS08115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7I86_RS08120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_RS08125	COG0457	Tetratricopeptide repeat
C7I86_RS08130	COG1160	GTP binding
C7I86_RS08150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7I86_RS08165	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7I86_RS08170	COG0052	Belongs to the universal ribosomal protein uS2 family
C7I86_RS08180	COG0387	Pfam Sodium calcium exchanger
C7I86_RS08185	COG0717	Belongs to the dCTP deaminase family
C7I86_RS08215	COG3385	transposase activity
C7I86_RS08220	COG1253	flavin adenine dinucleotide binding
C7I86_RS08230	COG3046	protein related to deoxyribodipyrimidine photolyase
C7I86_RS08235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7I86_RS08235	COG0617	tRNA 3'-terminal CCA addition
C7I86_RS08235	COG0517	IMP dehydrogenase activity
C7I86_RS08245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7I86_RS08265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7I86_RS08265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7I86_RS08270	COG0288	reversible hydration of carbon dioxide
C7I86_RS08275	COG1045	serine acetyltransferase
C7I86_RS08285	COG0166	Belongs to the GPI family
C7I86_RS08290	COG3239	Fatty acid desaturase
C7I86_RS08295	COG1672	PFAM Archaeal ATPase
C7I86_RS08300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7I86_RS08305	COG2010	Cytochrome c
C7I86_RS08310	COG0359	binds to the 23S rRNA
C7I86_RS08320	COG1032	radical SAM domain protein
C7I86_RS08350	COG0298	carbon dioxide binding
C7I86_RS08355	COG0109	protoheme IX farnesyltransferase activity
C7I86_RS08360	COG1612	heme a metabolic process
C7I86_RS08385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C7I86_RS08390	COG5001	Diguanylate cyclase
C7I86_RS08390	COG1716	ATPase activity
C7I86_RS08395	COG3631	Ketosteroid isomerase-related protein
C7I86_RS08405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7I86_RS08405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7I86_RS08415	COG0107	imidazoleglycerol-phosphate synthase activity
C7I86_RS08440	COG2205	protein histidine kinase activity
C7I86_RS08440	COG2202	Pas domain
C7I86_RS08460	COG3437	response regulator, receiver
C7I86_RS08460	COG2205	protein histidine kinase activity
C7I86_RS08460	COG3850	Histidine kinase
C7I86_RS08460	COG4999	Histidine kinase
C7I86_RS08470	COG4956	integral membrane protein (PIN domain superfamily)
C7I86_RS08485	COG1160	GTP binding
C7I86_RS08495	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7I86_RS08510	COG0432	Pfam Uncharacterised protein family UPF0047
C7I86_RS08515	COG2197	response regulator
C7I86_RS08520	COG3842	ATPase activity
C7I86_RS08530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7I86_RS08535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7I86_RS08545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7I86_RS08550	COG5398	heme oxygenase
C7I86_RS08555	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_RS08565	COG1316	TRANSCRIPTIONal
C7I86_RS08580	COG2208	phosphoserine phosphatase activity
C7I86_RS08580	COG2770	Histidine kinase
C7I86_RS08585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7I86_RS08595	COG0539	negative regulation of cytoplasmic translation
C7I86_RS08600	COG0358	DNA primase activity
C7I86_RS08610	COG0009	L-threonylcarbamoyladenylate synthase
C7I86_RS08630	COG0589	response to stress
C7I86_RS08655	COG2082	Precorrin-8x methylmutase
C7I86_RS08665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7I86_RS08670	COG0594	ribonuclease P activity
C7I86_RS08680	COG0706	membrane insertase activity
C7I86_RS08690	COG0484	heat shock protein binding
C7I86_RS08695	COG0483	inositol monophosphate 1-phosphatase activity
C7I86_RS08700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_RS08715	COG0791	NLP P60 protein
C7I86_RS08730	COG0540	Belongs to the ATCase OTCase family
C7I86_RS08745	COG1215	transferase activity, transferring glycosyl groups
C7I86_RS08755	COG0300	oxidoreductase activity
C7I86_RS08755	COG3000	fatty acid hydroxylase
C7I86_RS08765	COG2211	Major facilitator Superfamily
C7I86_RS08780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_RS08795	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_RS08805	COG2274	protein secretion by the type I secretion system
C7I86_RS08815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7I86_RS08820	COG2192	nodulation
C7I86_RS08830	COG0772	Belongs to the SEDS family
C7I86_RS08835	COG0405	Gamma-glutamyltransferase
C7I86_RS08850	COG3659	wide pore channel activity
C7I86_RS08890	COG0037	tRNA processing
C7I86_RS08895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7I86_RS08900	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS08905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS08910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS08965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_RS08980	COG0628	permease
C7I86_RS08995	COG0066	3-isopropylmalate dehydratase activity
C7I86_RS09000	COG0504	CTP synthase activity
C7I86_RS09015	COG2204	response regulator
C7I86_RS09025	COG0259	pyridoxamine-phosphate oxidase activity
C7I86_RS09045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7I86_RS09055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7I86_RS09060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7I86_RS09065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7I86_RS09065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7I86_RS09070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7I86_RS09080	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7I86_RS09085	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS09100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C7I86_RS09110	COG0051	transcription antitermination factor activity, RNA binding
C7I86_RS09115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7I86_RS09120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_RS09125	COG0049	tRNA binding
C7I86_RS09130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7I86_RS09140	COG0151	Belongs to the GarS family
C7I86_RS09150	COG0698	ribose 5-phosphate isomerase
C7I86_RS09180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7I86_RS09185	COG2046	Belongs to the sulfate adenylyltransferase family
C7I86_RS09190	COG0297	glycogen (starch) synthase activity
C7I86_RS09205	COG0644	oxidoreductase
C7I86_RS09210	COG0371	Dehydrogenase
C7I86_RS09225	COG2119	membrane
C7I86_RS09230	COG0386	Belongs to the glutathione peroxidase family
C7I86_RS09245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7I86_RS09265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7I86_RS09270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C7I86_RS09280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7I86_RS09285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7I86_RS09295	COG0375	protein maturation
C7I86_RS09310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7I86_RS09315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7I86_RS09320	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C7I86_RS09325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7I86_RS09330	COG1134	teichoic acid transport
C7I86_RS09365	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_RS09380	COG3385	transposase activity
C7I86_RS09420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_RS09430	COG1304	FMN binding
C7I86_RS09435	COG0745	RESPONSE REGULATOR receiver
C7I86_RS09445	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7I86_RS09455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7I86_RS09455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7I86_RS09460	COG3706	GGDEF domain
C7I86_RS09460	COG4251	negative regulation of phosphorylation
C7I86_RS09460	COG2203	Gaf domain
C7I86_RS09460	COG5001	Diguanylate cyclase
C7I86_RS09465	COG0784	Response regulator, receiver
C7I86_RS09475	COG0072	phenylalanine-tRNA ligase activity
C7I86_RS09475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7I86_RS09480	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS09480	COG0515	serine threonine protein kinase
C7I86_RS09485	COG2197	response regulator
C7I86_RS09490	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C7I86_RS09505	COG0157	Belongs to the NadC ModD family
C7I86_RS09520	COG2082	Precorrin-8x methylmutase
C7I86_RS09525	COG0612	Peptidase, M16
C7I86_RS09530	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7I86_RS09540	COG0656	L-ascorbic acid biosynthetic process
C7I86_RS09545	COG3588	fructose-bisphosphate aldolase
C7I86_RS09555	COG0798	PFAM Bile acid sodium symporter
C7I86_RS09560	COG0431	NADPH-dependent FMN reductase
C7I86_RS09565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7I86_RS09585	COG0488	(ABC) transporter
C7I86_RS09595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7I86_RS09615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7I86_RS09620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7I86_RS09625	COG0561	phosphatase activity
C7I86_RS09630	COG1366	Belongs to the anti-sigma-factor antagonist family
C7I86_RS09635	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7I86_RS09640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7I86_RS09650	COG0215	cysteine-tRNA ligase activity
C7I86_RS09655	COG0424	maF-like protein
C7I86_RS09670	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C7I86_RS09675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7I86_RS09680	COG0463	Glycosyl transferase, family 2
C7I86_RS09685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7I86_RS09700	COG1472	Belongs to the glycosyl hydrolase 3 family
C7I86_RS09705	COG2816	NAD+ diphosphatase activity
C7I86_RS09710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7I86_RS09715	COG1280	lysine exporter protein (LysE YggA)
C7I86_RS09730	COG0564	pseudouridine synthase activity
C7I86_RS09740	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS09765	COG3385	transposase activity
C7I86_RS09785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7I86_RS09800	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS09810	COG0500	methyltransferase
C7I86_RS09815	COG0542	response to heat
C7I86_RS09825	COG0572	uridine kinase
C7I86_RS09830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7I86_RS09835	COG0561	phosphatase activity
C7I86_RS09850	COG0571	ribonuclease III activity
C7I86_RS09855	COG0390	transport system, permease component
C7I86_RS09860	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
C7I86_RS09865	COG2161	toxin-antitoxin pair type II binding
C7I86_RS09880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7I86_RS09885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_RS09885	COG0426	domain, Protein
C7I86_RS09890	COG0497	DNA recombination
C7I86_RS09900	COG3751	2OG-Fe(II) oxygenase superfamily
C7I86_RS09930	COG2161	toxin-antitoxin pair type II binding
C7I86_RS09935	COG4115	mRNA cleavage
C7I86_RS09960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7I86_RS09965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_RS09980	COG1446	asparaginase
C7I86_RS09985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7I86_RS09995	COG0832	Belongs to the urease beta subunit family
C7I86_RS10005	COG2226	methyltransferase
C7I86_RS10020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7I86_RS10030	COG0025	NhaP-type Na H and K H
C7I86_RS10040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7I86_RS10050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7I86_RS10090	COG3239	Fatty acid desaturase
C7I86_RS10100	COG1950	PFAM Membrane protein of
C7I86_RS10115	COG1253	flavin adenine dinucleotide binding
C7I86_RS10120	COG0228	four-way junction DNA binding
C7I86_RS10140	COG2010	Cytochrome c
C7I86_RS10155	COG0802	atpase or kinase
C7I86_RS10160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7I86_RS10160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7I86_RS10190	COG0126	phosphoglycerate kinase activity
C7I86_RS10195	COG0583	DNA-binding transcription factor activity
C7I86_RS10200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7I86_RS10235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7I86_RS10250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7I86_RS10255	COG0347	Belongs to the P(II) protein family
C7I86_RS10270	COG0135	phosphoribosylanthranilate isomerase activity
C7I86_RS10275	COG0697	spore germination
C7I86_RS10295	COG0418	dihydroorotase activity
C7I86_RS10300	COG2226	methyltransferase
C7I86_RS10315	COG2319	Wd-40 repeat
C7I86_RS10315	COG1672	PFAM Archaeal ATPase
C7I86_RS10355	COG2815	serine threonine protein kinase
C7I86_RS10355	COG0515	serine threonine protein kinase
C7I86_RS10380	COG0233	cytoplasmic translational termination
C7I86_RS10385	COG0528	UMP kinase activity
C7I86_RS10390	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_RS10400	COG0542	response to heat
C7I86_RS10425	COG1459	type II secretion system
C7I86_RS10430	COG0740	serine-type endopeptidase activity
C7I86_RS10435	COG0740	serine-type endopeptidase activity
C7I86_RS10440	COG0006	proline dipeptidase activity
C7I86_RS10445	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7I86_RS10465	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
C7I86_RS10475	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C7I86_RS10515	COG2165	general secretion pathway protein
C7I86_RS10525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7I86_RS10565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7I86_RS10585	COG0105	UTP biosynthetic process
C7I86_RS10610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7I86_RS10615	COG2937	Belongs to the GPAT DAPAT family
C7I86_RS10625	COG0501	Belongs to the peptidase M48B family
C7I86_RS10645	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_RS10655	COG0463	Glycosyl transferase, family 2
C7I86_RS10665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7I86_RS10680	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7I86_RS10690	COG2217	Heavy metal translocating P-type atpase
C7I86_RS10700	COG0217	transcriptional regulatory protein
C7I86_RS10705	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C7I86_RS10710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7I86_RS10715	COG0739	heme binding
C7I86_RS10720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7I86_RS10725	COG0321	lipoyl(octanoyl) transferase activity
C7I86_RS10740	COG0297	glycogen (starch) synthase activity
C7I86_RS10755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_RS10760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7I86_RS10765	COG2198	Histidine kinase
C7I86_RS10765	COG0784	Response regulator, receiver
C7I86_RS10765	COG0643	Histidine kinase
C7I86_RS10765	COG0643	Histidine kinase
C7I86_RS10765	COG0784	Response regulator, receiver
C7I86_RS10765	COG2198	Histidine kinase
C7I86_RS10785	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS10800	COG1178	ABC-type Fe3 transport system permease component
C7I86_RS10805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7I86_RS10830	COG2197	response regulator
C7I86_RS10835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS10840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS10865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_RS10865	COG0237	dephospho-CoA kinase activity
C7I86_RS10905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS10915	COG0516	GMP reductase activity
C7I86_RS10915	COG0517	IMP dehydrogenase activity
C7I86_RS10925	COG1937	Protein conserved in bacteria
C7I86_RS10940	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C7I86_RS10960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7I86_RS10965	COG0443	Heat shock 70 kDa protein
C7I86_RS10985	COG1587	Uroporphyrinogen-III synthase
C7I86_RS10990	COG2319	Wd-40 repeat
C7I86_RS11010	COG3385	transposase activity
C7I86_RS11020	COG1381	Involved in DNA repair and RecF pathway recombination
C7I86_RS11040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7I86_RS11060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7I86_RS11065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7I86_RS11070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7I86_RS11075	COG5001	Diguanylate cyclase
C7I86_RS11085	COG1187	pseudouridine synthase activity
C7I86_RS11090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7I86_RS11120	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_RS11125	COG5002	protein histidine kinase activity
C7I86_RS11130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7I86_RS11135	COG2308	Evidence 4 Homologs of previously reported genes of
C7I86_RS11165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7I86_RS11175	COG0346	lactoylglutathione lyase activity
C7I86_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS11190	COG0742	ribosomal rna small subunit methyltransferase
C7I86_RS11195	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS11205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7I86_RS11225	COG1104	cysteine desulfurase activity
C7I86_RS11230	COG1040	competence protein
C7I86_RS11235	COG1376	ErfK ybiS ycfS ynhG family protein
C7I86_RS11250	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_RS11260	COG3659	wide pore channel activity
C7I86_RS11265	COG0477	Major facilitator Superfamily
C7I86_RS11270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7I86_RS11275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7I86_RS11280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_RS11285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7I86_RS11290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7I86_RS11295	COG2003	Belongs to the UPF0758 family
C7I86_RS11300	COG1054	Belongs to the UPF0176 family
C7I86_RS11310	COG0411	ABC transporter
C7I86_RS11330	COG1131	(ABC) transporter
C7I86_RS11340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7I86_RS11350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7I86_RS11360	COG0450	alkyl hydroperoxide reductase
C7I86_RS11365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7I86_RS11375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7I86_RS11385	COG1231	oxidoreductase activity
C7I86_RS11390	COG2205	protein histidine kinase activity
C7I86_RS11400	COG0149	triose-phosphate isomerase activity
C7I86_RS11405	COG0628	permease
C7I86_RS11420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7I86_RS11425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7I86_RS11440	COG0571	ribonuclease III activity
C7I86_RS11445	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C7I86_RS11470	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7I86_RS11515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_RS11520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7I86_RS11545	COG1748	Saccharopine dehydrogenase
C7I86_RS11555	COG0601	transmembrane transport
C7I86_RS11560	COG0124	histidyl-tRNA synthetase
C7I86_RS11605	COG0542	response to heat
C7I86_RS11610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7I86_RS11615	COG0191	fructose-bisphosphate aldolase activity
C7I86_RS11620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7I86_RS11640	COG0793	Belongs to the peptidase S41A family
C7I86_RS11645	COG1850	ribulose-bisphosphate carboxylase activity
C7I86_RS11655	COG4451	ribulose bisphosphate carboxylase, small
C7I86_RS11665	COG1285	pathogenesis
C7I86_RS11675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_RS11680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7I86_RS11690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7I86_RS11695	COG0114	fumarate hydratase activity
C7I86_RS11725	COG0436	Aminotransferase
C7I86_RS11730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_RS11735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7I86_RS11740	COG0616	signal peptide processing
C7I86_RS11745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7I86_RS11760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7I86_RS11760	COG0519	Catalyzes the synthesis of GMP from XMP
C7I86_RS11770	COG1968	undecaprenyl-diphosphatase activity
C7I86_RS11790	COG5322	oxidoreductase activity
C7I86_RS11795	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7I86_RS11805	COG0751	glycine-tRNA ligase activity
C7I86_RS11820	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7I86_RS11825	COG5002	protein histidine kinase activity
C7I86_RS11830	COG0445	tRNA wobble uridine modification
C7I86_RS11845	COG3794	PFAM blue (type 1) copper domain protein
C7I86_RS11860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_RS11865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7I86_RS11870	COG0805	protein transport
C7I86_RS11875	COG2084	Dehydrogenase
C7I86_RS11890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7I86_RS11900	COG0586	Pfam SNARE associated Golgi protein
C7I86_RS11905	COG3118	belongs to the thioredoxin family
C7I86_RS11910	COG3751	2OG-Fe(II) oxygenase superfamily
C7I86_RS11915	COG0459	protein refolding
C7I86_RS11920	COG1131	(ABC) transporter
C7I86_RS11945	COG4399	Belongs to the UPF0754 family
C7I86_RS11950	COG0824	Thioesterase
C7I86_RS11955	COG4948	Mandelate Racemase Muconate Lactonizing
C7I86_RS11960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7I86_RS11965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7I86_RS11970	COG0511	ligase activity, forming carbon-carbon bonds
C7I86_RS11975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C7I86_RS12000	COG0277	FAD linked oxidase domain protein
C7I86_RS12030	COG0436	Aminotransferase
C7I86_RS12035	COG0372	Belongs to the citrate synthase family
C7I86_RS12040	COG2062	phosphohistidine phosphatase, SixA
C7I86_RS12045	COG0596	Alpha beta hydrolase
C7I86_RS12060	COG1234	tRNA 3'-trailer cleavage
C7I86_RS12075	COG0788	formyltetrahydrofolate deformylase activity
C7I86_RS12095	COG0625	glutathione transferase activity
C7I86_RS12105	COG0440	acetolactate synthase activity
C7I86_RS12115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7I86_RS12120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7I86_RS12130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_RS12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7I86_RS12145	COG0628	permease
C7I86_RS12180	COG0628	permease
C7I86_RS12185	COG0443	Heat shock 70 kDa protein
C7I86_RS12190	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7I86_RS12195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7I86_RS12200	COG0116	Belongs to the methyltransferase superfamily
C7I86_RS12210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7I86_RS12210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7I86_RS12220	COG0612	Peptidase, M16
C7I86_RS12225	COG0489	protein tyrosine kinase activity
C7I86_RS12230	COG0439	Biotin carboxylase
C7I86_RS12235	COG3224	Antibiotic biosynthesis monooxygenase
C7I86_RS12240	COG0590	tRNA wobble adenosine to inosine editing
C7I86_RS12245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7I86_RS12260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7I86_RS12275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7I86_RS12280	COG4251	negative regulation of phosphorylation
C7I86_RS12285	COG0784	Response regulator, receiver
C7I86_RS12290	COG0556	nucleotide-excision repair
C7I86_RS12315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7I86_RS12320	COG2890	protein-(glutamine-N5) methyltransferase activity
C7I86_RS12325	COG0525	valine-tRNA ligase activity
C7I86_RS12330	COG5002	protein histidine kinase activity
C7I86_RS12340	COG0728	peptidoglycan biosynthetic process
C7I86_RS12355	COG0318	PFAM AMP-dependent synthetase and ligase
C7I86_RS12370	COG0460	homoserine dehydrogenase
C7I86_RS12375	COG2091	lysine biosynthetic process via aminoadipic acid
C7I86_RS12385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7I86_RS12405	COG0475	glutathione-regulated potassium exporter activity
C7I86_RS12420	COG4232	protein-disulfide reductase activity
C7I86_RS12430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_RS12435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7I86_RS12440	COG0581	inorganic phosphate transmembrane transporter activity
C7I86_RS12455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7I86_RS12470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7I86_RS12475	COG1842	Phage shock protein A
C7I86_RS12490	COG0653	protein targeting
C7I86_RS12495	COG2119	membrane
C7I86_RS12505	COG2255	four-way junction helicase activity
C7I86_RS12510	COG2022	thiamine diphosphate biosynthetic process
C7I86_RS12510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7I86_RS12520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7I86_RS12530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C7I86_RS12540	COG0752	glycyl-tRNA synthetase alpha subunit
C7I86_RS12545	COG0668	transmembrane transport
C7I86_RS12550	COG5002	protein histidine kinase activity
C7I86_RS12565	COG2211	Major facilitator Superfamily
C7I86_RS12580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7I86_RS12585	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7I86_RS12615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7I86_RS12625	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C7I86_RS12635	COG0745	RESPONSE REGULATOR receiver
C7I86_RS12640	COG0406	alpha-ribazole phosphatase activity
C7I86_RS12650	COG0475	glutathione-regulated potassium exporter activity
C7I86_RS12650	COG0589	response to stress
C7I86_RS12665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7I86_RS12675	COG1122	ATPase activity
C7I86_RS12685	COG0310	cobalt ion transport
C7I86_RS12710	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS12715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7I86_RS12730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7I86_RS12735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7I86_RS12745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7I86_RS12760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7I86_RS12775	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_RS12785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7I86_RS12795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7I86_RS12800	COG0302	gtp cyclohydrolase
C7I86_RS12805	COG1058	Belongs to the CinA family
C7I86_RS12805	COG1546	Belongs to the CinA family
C7I86_RS12810	COG0792	nuclease activity
C7I86_RS12820	COG2385	sporulation resulting in formation of a cellular spore
C7I86_RS12820	COG2247	cell wall binding repeat
C7I86_RS12825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7I86_RS12835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7I86_RS12860	COG0121	glutamine amidotransferase
C7I86_RS12865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_RS12875	COG2048	Heterodisulfide reductase, subunit B
C7I86_RS12880	COG0762	integral membrane protein
C7I86_RS12895	COG4178	(ABC) transporter
C7I86_RS12920	COG0824	Thioesterase
C7I86_RS12925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7I86_RS12950	COG2205	protein histidine kinase activity
C7I86_RS12950	COG2202	Pas domain
C7I86_RS12965	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7I86_RS12970	COG0646	methionine synthase
C7I86_RS12970	COG1410	methionine synthase
C7I86_RS13005	COG0646	methionine synthase
C7I86_RS13005	COG1410	methionine synthase
C7I86_RS13020	COG1309	transcriptional regulator
C7I86_RS13025	COG0534	Mate efflux family protein
C7I86_RS13040	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
C7I86_RS13045	COG0303	'Molybdopterin
C7I86_RS13050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7I86_RS13055	COG0315	cyclic pyranopterin monophosphate synthase activity
C7I86_RS13055	COG0746	molybdenum cofactor guanylyltransferase activity
C7I86_RS13065	COG0314	molybdopterin synthase activity
C7I86_RS13075	COG0606	chelatase, subunit chli
C7I86_RS13080	COG1032	radical SAM domain protein
C7I86_RS13120	COG0156	8-amino-7-oxononanoate synthase activity
C7I86_RS13125	COG0024	Methionine aminopeptidase
C7I86_RS13135	COG0494	nUDIX hydrolase
C7I86_RS13140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7I86_RS13145	COG0039	L-malate dehydrogenase activity
C7I86_RS13160	COG0193	aminoacyl-tRNA hydrolase activity
C7I86_RS13190	COG0024	Methionine aminopeptidase
C7I86_RS13195	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
C7I86_RS13210	COG4243	Vitamin k epoxide reductase
C7I86_RS13215	COG0426	domain, Protein
C7I86_RS13215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7I86_RS13220	COG0613	PHP domain protein
C7I86_RS13225	COG2251	uridine kinase activity
C7I86_RS13230	COG3063	Type IV pilus biogenesis stability protein PilW
C7I86_RS13235	COG0023	Translation Initiation Factor
C7I86_RS13285	COG2124	cytochrome p450
C7I86_RS13295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7I86_RS13310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7I86_RS13335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_RS13345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7I86_RS13350	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7I86_RS13355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7I86_RS13365	COG2203	Gaf domain
C7I86_RS13365	COG3706	GGDEF domain
C7I86_RS13365	COG4251	negative regulation of phosphorylation
C7I86_RS13365	COG5001	Diguanylate cyclase
C7I86_RS13370	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_RS13375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7I86_RS13390	COG0305	Participates in initiation and elongation during chromosome replication
C7I86_RS13390	COG1372	Participates in initiation and elongation during chromosome replication
C7I86_RS13395	COG0714	Associated with various cellular activities
C7I86_RS13410	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_RS13415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7I86_RS13420	COG2226	methyltransferase
C7I86_RS13425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7I86_RS13430	COG0154	amidase activity
C7I86_RS13450	COG5001	Diguanylate cyclase
C7I86_RS13450	COG4251	negative regulation of phosphorylation
C7I86_RS13450	COG3706	GGDEF domain
C7I86_RS13450	COG2203	Gaf domain
C7I86_RS13455	COG0617	tRNA 3'-terminal CCA addition
C7I86_RS13465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_RS13480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7I86_RS13490	COG1959	2 iron, 2 sulfur cluster binding
C7I86_RS13495	COG2203	Gaf domain
C7I86_RS13495	COG3706	GGDEF domain
C7I86_RS13495	COG4251	negative regulation of phosphorylation
C7I86_RS13495	COG5001	Diguanylate cyclase
C7I86_RS13500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7I86_RS13510	COG0357	Ribosomal RNA small subunit methyltransferase G
C7I86_RS13525	COG0719	Fe-S assembly protein
C7I86_RS13530	COG0396	ATPase activity
C7I86_RS13535	COG0719	Fe-S assembly protein
C7I86_RS13540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7I86_RS13545	COG0003	Pfam Anion-transporting ATPase
C7I86_RS13560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7I86_RS13565	COG0720	synthase
C7I86_RS13580	COG0328	RNA-DNA hybrid ribonuclease activity
C7I86_RS13585	COG0745	RESPONSE REGULATOR receiver
C7I86_RS13590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7I86_RS13595	COG0513	Belongs to the DEAD box helicase family
C7I86_RS13600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7I86_RS13605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7I86_RS13610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7I86_RS13615	COG0443	Heat shock 70 kDa protein
C7I86_RS13625	COG2226	methyltransferase
C7I86_RS13630	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C7I86_RS13635	COG1012	belongs to the aldehyde dehydrogenase family
C7I86_RS13640	COG1216	Glycosyl transferase, family 2
C7I86_RS13645	COG0484	heat shock protein binding
C7I86_RS13655	COG0659	secondary active sulfate transmembrane transporter activity
C7I86_RS13665	COG1131	(ABC) transporter
C7I86_RS13670	COG0131	Imidazoleglycerol-phosphate dehydratase
C7I86_RS13680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_RS13685	COG4251	negative regulation of phosphorylation
C7I86_RS13690	COG2197	response regulator
C7I86_RS13705	COG0515	serine threonine protein kinase
C7I86_RS13715	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS13730	COG0436	Aminotransferase
C7I86_RS13735	COG0586	Pfam SNARE associated Golgi protein
C7I86_RS13740	COG3264	Mechanosensitive ion channel
C7I86_RS13740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7I86_RS13760	COG0848	biopolymer transport protein
C7I86_RS13765	COG0848	biopolymer transport protein
C7I86_RS13770	COG0811	peptide transport
C7I86_RS13775	COG1840	ABC-type Fe3 transport system, periplasmic component
C7I86_RS13785	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS13790	COG2205	protein histidine kinase activity
C7I86_RS13800	COG0456	acetyltransferase
C7I86_RS13810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7I86_RS13815	COG0047	phosphoribosylformylglycinamidine synthase activity
C7I86_RS13840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7I86_RS13845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7I86_RS13850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7I86_RS13855	COG0628	permease
C7I86_RS13870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_RS13875	COG0837	glucose binding
C7I86_RS13880	COG1132	(ABC) transporter
C7I86_RS13900	COG0668	transmembrane transport
C7I86_RS13905	COG1492	cobalamin metabolic process
C7I86_RS13925	COG0469	pyruvate kinase activity
C7I86_RS13930	COG2081	HI0933 family
C7I86_RS13935	COG3118	belongs to the thioredoxin family
C7I86_RS13950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7I86_RS13965	COG0457	Tetratricopeptide repeat
C7I86_RS13965	COG0463	Glycosyl transferase, family 2
C7I86_RS13980	COG0004	ammonium transporteR
C7I86_RS13985	COG0800	Aldolase
C7I86_RS13995	COG1480	7TM receptor with intracellular HD hydrolase
C7I86_RS14000	COG2304	oxidoreductase activity
C7I86_RS14010	COG1192	Involved in chromosome partitioning
C7I86_RS14025	COG1473	amidohydrolase
C7I86_RS14035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7I86_RS14060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7I86_RS14065	COG2205	protein histidine kinase activity
C7I86_RS14065	COG0784	Response regulator, receiver
C7I86_RS14070	COG1192	Involved in chromosome partitioning
C7I86_RS14090	COG0745	RESPONSE REGULATOR receiver
C7I86_RS14105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7I86_RS14115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C7I86_RS14125	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7I86_RS14140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C7I86_RS14145	COG2894	cell division
C7I86_RS14150	COG0850	regulation of cytokinetic process
C7I86_RS14155	COG1716	ATPase activity
C7I86_RS14170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7I86_RS14170	COG0574	Belongs to the PEP-utilizing enzyme family
C7I86_RS14190	COG0398	Pfam SNARE associated Golgi protein
C7I86_RS14195	COG0737	Belongs to the 5'-nucleotidase family
C7I86_RS14200	COG0454	-acetyltransferase
C7I86_RS14215	COG1032	radical SAM domain protein
C7I86_RS14240	COG4585	Histidine kinase
C7I86_RS14245	COG2197	response regulator
C7I86_RS14250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7I86_RS14250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7I86_RS14255	COG2267	carboxylic ester hydrolase activity
C7I86_RS14260	COG4221	oxidoreductase activity
C7I86_RS14295	COG0024	Methionine aminopeptidase
C7I86_RS14315	COG1051	belongs to the nudix hydrolase family
C7I86_RS14315	COG1056	cytidyltransferase-related domain
C7I86_RS14330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7I86_RS14335	COG5002	protein histidine kinase activity
C7I86_RS14360	COG2814	Major facilitator Superfamily
C7I86_RS14370	COG2217	Heavy metal translocating P-type atpase
C7I86_RS14375	COG1742	UPF0060 membrane protein
C7I86_RS14380	COG0640	Transcriptional regulator
C7I86_RS14385	COG2217	Heavy metal translocating P-type atpase
C7I86_RS14390	COG5002	protein histidine kinase activity
C7I86_RS14395	COG0745	RESPONSE REGULATOR receiver
C7I86_RS14420	COG2144	transferase activity, transferring acyl groups
C7I86_RS14445	COG2072	flavoprotein involved in K transport
C7I86_RS14450	COG2197	response regulator
C7I86_RS14465	COG2203	Gaf domain
C7I86_RS14465	COG5001	Diguanylate cyclase
C7I86_RS14465	COG4251	negative regulation of phosphorylation
C7I86_RS14465	COG3706	GGDEF domain
C7I86_RS14470	COG1131	(ABC) transporter
C7I86_RS14470	COG1716	ATPase activity
C7I86_RS14470	COG0842	Transport permease protein
C7I86_RS14480	COG0515	serine threonine protein kinase
C7I86_RS14480	COG4991	sh3 domain protein
C7I86_RS14480	COG3064	Membrane
C7I86_RS14490	COG0401	homolog of Blt101
C7I86_RS14500	COG2954	triphosphatase activity
C7I86_RS14515	COG0789	Transcriptional regulator
C7I86_RS14565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7I86_RS14570	COG0598	Magnesium transport protein CorA
C7I86_RS14585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7I86_RS14585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7I86_RS14610	COG0251	oxidation-reduction process
C7I86_RS14615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7I86_RS14620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7I86_RS14625	COG0392	lysyltransferase activity
C7I86_RS14645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7I86_RS14670	COG2886	Uncharacterised protein family (UPF0175)
C7I86_RS14675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7I86_RS14680	COG0668	transmembrane transport
C7I86_RS14685	COG0205	6-phosphofructokinase activity
C7I86_RS14705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7I86_RS14705	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7I86_RS14705	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7I86_RS14705	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7I86_RS14715	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_RS14720	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7I86_RS14745	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS14760	COG0784	Response regulator, receiver
C7I86_RS14760	COG0643	Histidine kinase
C7I86_RS14760	COG2198	Histidine kinase
C7I86_RS14765	COG0840	transmembrane signaling receptor activity
C7I86_RS14770	COG0840	transmembrane signaling receptor activity
C7I86_RS14770	COG2203	Gaf domain
C7I86_RS14785	COG0784	Response regulator, receiver
C7I86_RS14795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7I86_RS14800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7I86_RS14805	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7I86_RS14810	COG1803	Methylglyoxal synthase
C7I86_RS14810	COG1597	lipid kinase activity
C7I86_RS14815	COG0436	Aminotransferase
C7I86_RS14840	COG0857	belongs to the CobB CobQ family
C7I86_RS14845	COG0583	DNA-binding transcription factor activity
C7I86_RS14850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_RS14855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7I86_RS14860	COG3659	wide pore channel activity
C7I86_RS14865	COG1116	anion transmembrane transporter activity
C7I86_RS14865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7I86_RS14870	COG1116	anion transmembrane transporter activity
C7I86_RS14875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS14880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7I86_RS14890	COG0724	RNA recognition motif
C7I86_RS14895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7I86_RS14900	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7I86_RS14905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7I86_RS14910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7I86_RS14915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C7I86_RS14920	COG1653	transport
C7I86_RS14925	COG1175	transmembrane transport
C7I86_RS14930	COG0395	ABC-type sugar transport system, permease component
C7I86_RS14940	COG2205	protein histidine kinase activity
C7I86_RS14945	COG0741	lytic transglycosylase activity
C7I86_RS14955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7I86_RS14970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7I86_RS14975	COG0598	Magnesium transport protein CorA
C7I86_RS14980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7I86_RS14985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7I86_RS14990	COG0019	diaminopimelate decarboxylase activity
C7I86_RS14995	COG1160	GTP binding
C7I86_RS15000	COG0018	arginyl-trna synthetase
C7I86_RS15005	COG0463	Glycosyl transferase, family 2
C7I86_RS15015	COG0740	serine-type endopeptidase activity
C7I86_RS15020	COG0133	tryptophan synthase activity
C7I86_RS15030	COG1136	(ABC) transporter
C7I86_RS15035	COG2314	TM2 domain
C7I86_RS15055	COG0017	Asparaginyl-tRNA synthetase
C7I86_RS15075	COG0569	domain protein
C7I86_RS15080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7I86_RS15085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7I86_RS15090	COG0629	single-stranded DNA binding
C7I86_RS15100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7I86_RS15110	COG1192	Involved in chromosome partitioning
C7I86_RS15120	COG2119	membrane
C7I86_RS15125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7I86_RS15130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7I86_RS15140	COG1162	GTPase activity
C7I86_RS15150	COG0484	heat shock protein binding
C7I86_RS15155	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7I86_RS15160	COG1218	3'(2'),5'-bisphosphate nucleotidase
C7I86_RS15170	COG0134	indole-3-glycerol-phosphate synthase activity
C7I86_RS15175	COG0004	ammonium transporteR
C7I86_RS15180	COG0569	domain protein
C7I86_RS15185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7I86_RS15190	COG0740	serine-type endopeptidase activity
C7I86_RS15195	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7I86_RS15200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7I86_RS15205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7I86_RS15210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7I86_RS15220	COG0237	dephospho-CoA kinase activity
C7I86_RS15235	COG1994	Peptidase M50
C7I86_RS15235	COG0517	IMP dehydrogenase activity
C7I86_RS15240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7I86_RS15260	COG0525	valine-tRNA ligase activity
C7I86_RS15265	COG0713	ATP synthesis coupled electron transport
C7I86_RS15270	COG0839	Belongs to the complex I subunit 6 family
C7I86_RS15275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7I86_RS15280	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C7I86_RS15285	COG0167	dihydroorotate dehydrogenase activity
C7I86_RS15290	COG2166	iron-sulfur cluster assembly
C7I86_RS15295	COG1070	Carbohydrate kinase
C7I86_RS15320	COG0308	aminopeptidase N
C7I86_RS15325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7I86_RS15330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7I86_RS15335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7I86_RS15345	COG2193	ferroxidase activity
C7I86_RS15355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7I86_RS15365	COG1834	amidinotransferase
C7I86_RS15370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_RS15400	COG0745	RESPONSE REGULATOR receiver
C7I86_RS15405	COG0483	inositol monophosphate 1-phosphatase activity
C7I86_RS15420	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7I86_RS15425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7I86_RS15430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7I86_RS15435	COG4208	sulfate ABC transporter
C7I86_RS15440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7I86_RS15445	COG2165	general secretion pathway protein
C7I86_RS15460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7I86_RS15475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7I86_RS15480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7I86_RS15485	COG0731	radical SAM domain protein
C7I86_RS15495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7I86_RS15500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7I86_RS15510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7I86_RS15515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7I86_RS15530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7I86_RS15585	COG0339	signal peptide processing
C7I86_RS15590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7I86_RS15615	COG1166	arginine decarboxylase activity
C7I86_RS15625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7I86_RS15645	COG1049	propionate catabolic process, 2-methylcitrate cycle
C7I86_RS15670	COG0067	glutamate synthase
C7I86_RS15670	COG0069	glutamate synthase activity
C7I86_RS15670	COG0070	glutamate synthase
C7I86_RS15675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7I86_RS15680	COG0505	Belongs to the CarA family
C7I86_RS15690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7I86_RS15695	COG0579	oxidoreductase
C7I86_RS15705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7I86_RS15710	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7I86_RS15715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7I86_RS15720	COG3001	Fructosamine kinase
C7I86_RS15730	COG1191	sigma factor activity
C7I86_RS15735	COG0316	Belongs to the HesB IscA family
C7I86_RS15740	COG0463	Glycosyl transferase, family 2
C7I86_RS15745	COG2319	Wd-40 repeat
C7I86_RS15760	COG1691	(AIR) carboxylase
C7I86_RS15765	COG0739	heme binding
C7I86_RS15785	COG1496	oxidoreductase activity
C7I86_RS15790	COG2052	Domain of unknown function (DUF370)
C7I86_RS15795	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7I86_RS15795	COG3264	Mechanosensitive ion channel
C7I86_RS15835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C7I86_RS15850	COG0363	glucosamine-6-phosphate deaminase activity
C7I86_RS15875	COG3385	transposase activity
C7I86_RS15880	COG5001	Diguanylate cyclase
C7I86_RS15880	COG2203	Gaf domain
C7I86_RS15880	COG4251	negative regulation of phosphorylation
C7I86_RS15880	COG3706	GGDEF domain
C7I86_RS15890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_RS15910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7I86_RS15915	COG3300	MHYT domain
C7I86_RS15915	COG5001	Diguanylate cyclase
C7I86_RS15925	COG3842	ATPase activity
C7I86_RS15935	COG1543	Belongs to the glycosyl hydrolase 57 family
C7I86_RS15945	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
C7I86_RS15955	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
C7I86_RS15965	COG0457	Tetratricopeptide repeat
C7I86_RS15970	COG0148	phosphopyruvate hydratase activity
C7I86_RS15980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7I86_RS15995	COG0825	malonyl-CoA metabolic process
C7I86_RS16020	COG1598	PFAM Uncharacterised protein family UPF0150
C7I86_RS16045	COG4251	negative regulation of phosphorylation
C7I86_RS16050	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
C7I86_RS16075	COG2994	toxin metabolic process
C7I86_RS16090	COG0170	dolichyl monophosphate biosynthetic process
C7I86_RS16095	COG1473	amidohydrolase
C7I86_RS16100	COG3659	wide pore channel activity
C7I86_RS16120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7I86_RS16125	COG4251	negative regulation of phosphorylation
C7I86_RS16125	COG5001	Diguanylate cyclase
C7I86_RS16125	COG3706	GGDEF domain
C7I86_RS16125	COG2203	Gaf domain
C7I86_RS16150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7I86_RS16180	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7I86_RS16195	COG2197	response regulator
C7I86_RS16240	COG2153	protein acetylation
C7I86_RS16290	COG4581	dead DEAH box helicase
C7I86_RS16300	COG0322	excinuclease ABC activity
C7I86_RS16305	COG0129	dihydroxy-acid dehydratase activity
C7I86_RS16310	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7I86_RS16340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7I86_RS16345	COG0546	phosphoglycolate phosphatase activity
C7I86_RS16370	COG0326	Molecular chaperone. Has ATPase activity
C7I86_RS16375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7I86_RS16390	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C7I86_RS16395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7I86_RS16405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7I86_RS16440	COG0723	plastoquinol--plastocyanin reductase activity
C7I86_RS16455	COG1842	Phage shock protein A
C7I86_RS16475	COG1064	alcohol dehydrogenase
C7I86_RS16480	COG0137	argininosuccinate synthase activity
C7I86_RS16495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7I86_RS16500	COG1357	PFAM Pentapeptide repeats (8 copies)
C7I86_RS16520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7I86_RS16535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7I86_RS16540	COG0549	Belongs to the carbamate kinase family
C7I86_RS16560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7I86_RS16565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7I86_RS16570	COG0577	efflux transmembrane transporter activity
C7I86_RS16570	COG1136	(ABC) transporter
C7I86_RS16575	COG0735	belongs to the Fur family
C7I86_RS16585	COG0138	bifunctional purine biosynthesis protein purh
C7I86_RS16605	COG0515	serine threonine protein kinase
C7I86_RS16630	COG0587	DNA-directed DNA polymerase activity
C7I86_RS16635	COG0481	GTPase activity
C7I86_RS16640	COG0435	Glutathione S-transferase
C7I86_RS16660	COG0140	phosphoribosyl-ATP diphosphatase activity
C7I86_RS16660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7I86_RS16665	COG0523	cobalamin synthesis protein
C7I86_RS16750	COG3385	transposase activity
C7I86_RS16850	COG4453	Protein conserved in bacteria
C7I86_RS16890	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7I86_RS16950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7I86_RS17005	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7I86_RS17060	COG1518	maintenance of DNA repeat elements
C7I86_RS17155	COG1468	defense response to virus
C7I86_RS17155	COG1518	maintenance of DNA repeat elements
C7I86_RS17210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7I86_RS17350	COG1846	Transcriptional regulator
C7I86_RS17395	COG2070	2-Nitropropane dioxygenase
C7I86_RS17415	COG2319	Wd-40 repeat
C7I86_RS17415	COG3903	Transcriptional regulator
C7I86_RS17530	COG1872	DUF167
C7I86_RS17570	COG2361	Protein of unknown function DUF86
C7I86_RS17585	COG3093	addiction module antidote protein HigA
C7I86_RS17590	COG1104	cysteine desulfurase activity
C7I86_RS17655	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7I86_RS17715	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS17725	COG0438	transferase activity, transferring glycosyl groups
C7I86_RS17760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7I86_RS17775	COG0784	Response regulator, receiver
C7I86_RS17775	COG5002	protein histidine kinase activity
C7I86_RS17775	COG2205	protein histidine kinase activity
C7I86_RS17855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7I86_RS17870	COG1028	Short-chain dehydrogenase reductase Sdr
C7I86_RS17880	COG3878	Protein conserved in bacteria
C7I86_RS17910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7I86_RS18010	COG1192	Involved in chromosome partitioning
C7I86_RS18100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7I86_RS18105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7I86_RS18140	COG5001	Diguanylate cyclase
C7I86_RS18145	COG4191	Histidine kinase
C7I86_RS18145	COG0784	Response regulator, receiver
C7I86_RS18305	COG1192	Involved in chromosome partitioning
C7I86_RS18325	COG0745	RESPONSE REGULATOR receiver
C7I86_RS18415	COG2340	Cysteine-rich secretory protein family
C7I86_RS18610	COG3177	Filamentation induced by cAMP protein fic
C7I86_RS18620	COG4680	protein conserved in bacteria
C7I86_RS18630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7I86_RS18635	COG1451	nucleotide metabolic process
C7I86_RS18645	COG3385	transposase activity
C7I86_RS18655	COG2340	Cysteine-rich secretory protein family