locus-tag	class	description
D082_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D082_RS00040	COG1657	PFAM Prenyltransferase squalene oxidase
D082_RS00045	COG3347	Dehydrogenase
D082_RS00045	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS00060	COG2203	Gaf domain
D082_RS00060	COG3706	GGDEF domain
D082_RS00060	COG4251	negative regulation of phosphorylation
D082_RS00060	COG5001	Diguanylate cyclase
D082_RS00070	COG0784	Response regulator, receiver
D082_RS00080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D082_RS00085	COG2239	Acts as a magnesium transporter
D082_RS00115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D082_RS00150	COG0616	signal peptide processing
D082_RS00160	COG0596	Alpha beta hydrolase
D082_RS00165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D082_RS00190	COG0745	RESPONSE REGULATOR receiver
D082_RS00195	COG0860	N-Acetylmuramoyl-L-alanine amidase
D082_RS00250	COG0312	modulator of DNA gyrase
D082_RS00255	COG0482	sulfurtransferase activity
D082_RS00265	COG0366	Alpha amylase catalytic
D082_RS00270	COG0488	(ABC) transporter
D082_RS00315	COG0114	fumarate hydratase activity
D082_RS00320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D082_RS00330	COG0312	modulator of DNA gyrase
D082_RS00350	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D082_RS00365	COG0424	maF-like protein
D082_RS00375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D082_RS00390	COG2140	Oxalate decarboxylase
D082_RS00395	COG0058	SHG alpha-glucan phosphorylase activity
D082_RS00410	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
D082_RS00410	COG0662	Cupin 2, conserved barrel domain protein
D082_RS00415	COG1799	cell septum assembly
D082_RS00420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D082_RS00445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D082_RS00450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D082_RS00460	COG3000	fatty acid hydroxylase
D082_RS00460	COG0300	oxidoreductase activity
D082_RS00470	COG1215	transferase activity, transferring glycosyl groups
D082_RS00480	COG2082	Precorrin-8x methylmutase
D082_RS00490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D082_RS00495	COG0594	ribonuclease P activity
D082_RS00505	COG0706	membrane insertase activity
D082_RS00515	COG0484	heat shock protein binding
D082_RS00525	COG1131	(ABC) transporter
D082_RS00540	COG0358	DNA primase activity
D082_RS00545	COG0539	negative regulation of cytoplasmic translation
D082_RS00560	COG2208	phosphoserine phosphatase activity
D082_RS00560	COG2770	Histidine kinase
D082_RS00580	COG1316	TRANSCRIPTIONal
D082_RS00610	COG0789	Transcriptional regulator
D082_RS00645	COG0538	isocitrate dehydrogenase activity
D082_RS00655	COG2814	Major facilitator Superfamily
D082_RS00665	COG0552	protein localization to endoplasmic reticulum
D082_RS00680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D082_RS00685	COG0581	inorganic phosphate transmembrane transporter activity
D082_RS00690	COG0573	inorganic phosphate transmembrane transporter activity
D082_RS00695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D082_RS00705	COG0435	Glutathione S-transferase
D082_RS00725	COG1049	propionate catabolic process, 2-methylcitrate cycle
D082_RS00735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D082_RS00745	COG1166	arginine decarboxylase activity
D082_RS00750	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D082_RS00750	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D082_RS00755	COG0602	queuosine metabolic process
D082_RS00760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D082_RS00765	COG0612	Peptidase, M16
D082_RS00770	COG0612	Peptidase, M16
D082_RS00780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D082_RS00785	COG0187	DNA topoisomerase II activity
D082_RS00785	COG1372	Participates in initiation and elongation during chromosome replication
D082_RS00800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D082_RS00800	COG0646	methionine synthase
D082_RS00815	COG1968	undecaprenyl-diphosphatase activity
D082_RS00820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D082_RS00840	COG0739	heme binding
D082_RS00850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D082_RS00855	COG0483	inositol monophosphate 1-phosphatase activity
D082_RS00860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D082_RS00870	COG0791	NLP P60 protein
D082_RS00885	COG0540	Belongs to the ATCase OTCase family
D082_RS00890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D082_RS00900	COG0716	FMN binding
D082_RS00905	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D082_RS00910	COG3536	Protein conserved in bacteria
D082_RS00915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D082_RS00920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D082_RS00935	COG0316	Belongs to the HesB IscA family
D082_RS00945	COG1136	(ABC) transporter
D082_RS00945	COG0577	efflux transmembrane transporter activity
D082_RS00970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS00975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS00980	COG2197	response regulator
D082_RS00995	COG0798	PFAM Bile acid sodium symporter
D082_RS01000	COG0431	NADPH-dependent FMN reductase
D082_RS01005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D082_RS01020	COG0488	(ABC) transporter
D082_RS01070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D082_RS01080	COG1492	cobalamin metabolic process
D082_RS01090	COG0804	urea catabolic process
D082_RS01100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D082_RS01120	COG1090	epimerase
D082_RS01125	COG3842	ATPase activity
D082_RS01140	COG2203	Gaf domain
D082_RS01140	COG4251	negative regulation of phosphorylation
D082_RS01140	COG3706	GGDEF domain
D082_RS01140	COG5001	Diguanylate cyclase
D082_RS01145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS01155	COG2205	protein histidine kinase activity
D082_RS01160	COG4279	zinc finger
D082_RS01180	COG0745	RESPONSE REGULATOR receiver
D082_RS01185	COG0583	DNA-binding transcription factor activity
D082_RS01190	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
D082_RS01205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D082_RS01205	COG1754	DNA topoisomerase type I activity
D082_RS01210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D082_RS01215	COG0640	Transcriptional regulator
D082_RS01220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D082_RS01235	COG2188	Transcriptional regulator
D082_RS01250	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D082_RS01265	COG0363	glucosamine-6-phosphate deaminase activity
D082_RS01305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D082_RS01320	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS01325	COG0805	protein transport
D082_RS01330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D082_RS01355	COG0564	pseudouridine synthase activity
D082_RS01370	COG0501	Belongs to the peptidase M48B family
D082_RS01385	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D082_RS01415	COG0456	acetyltransferase
D082_RS01425	COG0784	Response regulator, receiver
D082_RS01425	COG2205	protein histidine kinase activity
D082_RS01430	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS01440	COG1840	ABC-type Fe3 transport system, periplasmic component
D082_RS01445	COG0811	peptide transport
D082_RS01450	COG0848	biopolymer transport protein
D082_RS01455	COG0848	biopolymer transport protein
D082_RS01460	COG0251	oxidation-reduction process
D082_RS01465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D082_RS01470	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D082_RS01475	COG0392	lysyltransferase activity
D082_RS01495	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D082_RS01505	COG0343	queuine tRNA-ribosyltransferase activity
D082_RS01525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D082_RS01540	COG0587	DNA-directed DNA polymerase activity
D082_RS01555	COG1012	belongs to the aldehyde dehydrogenase family
D082_RS01560	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D082_RS01560	COG3264	Mechanosensitive ion channel
D082_RS01565	COG0586	Pfam SNARE associated Golgi protein
D082_RS01570	COG0436	Aminotransferase
D082_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS01595	COG0515	serine threonine protein kinase
D082_RS01610	COG0586	Pfam SNARE associated Golgi protein
D082_RS01615	COG3118	belongs to the thioredoxin family
D082_RS01620	COG1713	HD superfamily hydrolase involved in NAD metabolism
D082_RS01625	COG0799	negative regulation of ribosome biogenesis
D082_RS01650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D082_RS01655	COG1178	ABC-type Fe3 transport system permease component
D082_RS01670	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS01675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D082_RS01680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D082_RS01685	COG0668	transmembrane transport
D082_RS01690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D082_RS01695	COG2886	Uncharacterised protein family (UPF0175)
D082_RS01720	COG0077	Prephenate dehydratase
D082_RS01720	COG1605	Chorismate mutase
D082_RS01730	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D082_RS01745	COG2205	protein histidine kinase activity
D082_RS01750	COG0741	lytic transglycosylase activity
D082_RS01760	COG0483	inositol monophosphate 1-phosphatase activity
D082_RS01765	COG0546	phosphoglycolate phosphatase activity
D082_RS01770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D082_RS01780	COG0233	cytoplasmic translational termination
D082_RS01785	COG0528	UMP kinase activity
D082_RS01790	COG0542	response to heat
D082_RS01795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D082_RS01805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D082_RS01815	COG3956	TIGRFAM MazG family protein
D082_RS01830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D082_RS01835	COG0010	Belongs to the arginase family
D082_RS01840	COG0123	including yeast histone deacetylase and acetoin utilization protein
D082_RS01845	COG0589	response to stress
D082_RS01855	COG0011	TIGRFAM Protein of
D082_RS01860	COG1187	pseudouridine synthase activity
D082_RS01865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D082_RS01895	COG1012	belongs to the aldehyde dehydrogenase family
D082_RS01905	COG3384	dioxygenase
D082_RS01925	COG3659	wide pore channel activity
D082_RS01935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D082_RS01950	COG0515	serine threonine protein kinase
D082_RS01960	COG1187	pseudouridine synthase activity
D082_RS01965	COG0142	geranyltranstransferase activity
D082_RS01975	COG0523	cobalamin synthesis protein
D082_RS01980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D082_RS01980	COG0140	phosphoribosyl-ATP diphosphatase activity
D082_RS02000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D082_RS02015	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS02020	COG0023	Translation Initiation Factor
D082_RS02025	COG3063	Type IV pilus biogenesis stability protein PilW
D082_RS02030	COG0450	alkyl hydroperoxide reductase
D082_RS02035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D082_RS02045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D082_RS02055	COG1231	oxidoreductase activity
D082_RS02060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D082_RS02060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D082_RS02215	COG0700	Nucleoside recognition
D082_RS02225	COG0673	inositol 2-dehydrogenase activity
D082_RS02230	COG0436	Aminotransferase
D082_RS02235	COG1597	lipid kinase activity
D082_RS02235	COG1803	Methylglyoxal synthase
D082_RS02240	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D082_RS02250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D082_RS02265	COG3794	PFAM blue (type 1) copper domain protein
D082_RS02275	COG0445	tRNA wobble uridine modification
D082_RS02280	COG5002	protein histidine kinase activity
D082_RS02285	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D082_RS02300	COG0751	glycine-tRNA ligase activity
D082_RS02310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D082_RS02315	COG5322	oxidoreductase activity
D082_RS02320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D082_RS02335	COG0628	permease
D082_RS02340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D082_RS02345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D082_RS02350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D082_RS02370	COG0047	phosphoribosylformylglycinamidine synthase activity
D082_RS02375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D082_RS02385	COG0589	response to stress
D082_RS02390	COG2226	methyltransferase
D082_RS02400	COG1381	Involved in DNA repair and RecF pathway recombination
D082_RS02405	COG1619	proteins homologs of microcin C7 resistance protein MccF
D082_RS02415	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D082_RS02420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D082_RS02420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D082_RS02425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D082_RS02430	COG1268	BioY protein
D082_RS02435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D082_RS02445	COG0601	transmembrane transport
D082_RS02450	COG0124	histidyl-tRNA synthetase
D082_RS02495	COG0463	Glycosyl transferase, family 2
D082_RS02525	COG0542	response to heat
D082_RS02535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D082_RS02540	COG0191	fructose-bisphosphate aldolase activity
D082_RS02545	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D082_RS02550	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D082_RS02565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D082_RS02585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D082_RS02590	COG1446	asparaginase
D082_RS02595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D082_RS02605	COG0832	Belongs to the urease beta subunit family
D082_RS02610	COG2226	methyltransferase
D082_RS02625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D082_RS02630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D082_RS02640	COG1191	sigma factor activity
D082_RS02645	COG3001	Fructosamine kinase
D082_RS02650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D082_RS02655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D082_RS02660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D082_RS02675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D082_RS02685	COG2211	Major facilitator Superfamily
D082_RS02700	COG3659	wide pore channel activity
D082_RS02710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D082_RS02715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D082_RS02745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D082_RS02755	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D082_RS02765	COG0745	RESPONSE REGULATOR receiver
D082_RS02770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D082_RS02805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D082_RS02820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D082_RS02825	COG0347	Belongs to the P(II) protein family
D082_RS02835	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D082_RS02840	COG0339	signal peptide processing
D082_RS02860	COG1234	tRNA 3'-trailer cleavage
D082_RS02885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
D082_RS02890	COG3706	GGDEF domain
D082_RS02890	COG5001	Diguanylate cyclase
D082_RS02890	COG2203	Gaf domain
D082_RS02890	COG4251	negative regulation of phosphorylation
D082_RS02900	COG3273	potassium ion transport
D082_RS02900	COG0471	metal ion transport
D082_RS02940	COG2205	protein histidine kinase activity
D082_RS02940	COG2202	Pas domain
D082_RS02955	COG4783	chaperone-mediated protein folding
D082_RS02960	COG4999	Histidine kinase
D082_RS02960	COG3437	response regulator, receiver
D082_RS02960	COG3850	Histidine kinase
D082_RS02960	COG2205	protein histidine kinase activity
D082_RS02970	COG4956	integral membrane protein (PIN domain superfamily)
D082_RS02990	COG0577	efflux transmembrane transporter activity
D082_RS02990	COG1136	(ABC) transporter
D082_RS02995	COG2197	response regulator
D082_RS03000	COG4251	negative regulation of phosphorylation
D082_RS03005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D082_RS03015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D082_RS03020	COG0443	Heat shock 70 kDa protein
D082_RS03035	COG0443	Heat shock 70 kDa protein
D082_RS03040	COG0131	Imidazoleglycerol-phosphate dehydratase
D082_RS03060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D082_RS03070	COG1160	GTP binding
D082_RS03090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D082_RS03095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D082_RS03105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D082_RS03110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D082_RS03130	COG2319	Wd-40 repeat
D082_RS03135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D082_RS03150	COG0463	Glycosyl transferase, family 2
D082_RS03155	COG2268	Band 7 protein
D082_RS03160	COG0861	Integral membrane protein TerC family
D082_RS03165	COG0045	succinate-CoA ligase (ADP-forming) activity
D082_RS03175	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D082_RS03185	COG1054	Belongs to the UPF0176 family
D082_RS03190	COG2247	cell wall binding repeat
D082_RS03190	COG2385	sporulation resulting in formation of a cellular spore
D082_RS03200	COG0792	nuclease activity
D082_RS03205	COG1546	Belongs to the CinA family
D082_RS03205	COG1058	Belongs to the CinA family
D082_RS03210	COG0302	gtp cyclohydrolase
D082_RS03215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D082_RS03225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D082_RS03235	COG1598	PFAM Uncharacterised protein family UPF0150
D082_RS03250	COG0438	transferase activity, transferring glycosyl groups
D082_RS03265	COG0643	Histidine kinase
D082_RS03265	COG0784	Response regulator, receiver
D082_RS03265	COG2198	Histidine kinase
D082_RS03275	COG0840	transmembrane signaling receptor activity
D082_RS03275	COG2203	Gaf domain
D082_RS03290	COG0784	Response regulator, receiver
D082_RS03300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D082_RS03305	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D082_RS03325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D082_RS03335	COG1234	tRNA 3'-trailer cleavage
D082_RS03350	COG0788	formyltetrahydrofolate deformylase activity
D082_RS03370	COG0625	glutathione transferase activity
D082_RS03380	COG0440	acetolactate synthase activity
D082_RS03390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D082_RS03395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D082_RS03405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D082_RS03420	COG0628	permease
D082_RS03460	COG0563	adenylate kinase activity
D082_RS03465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D082_RS03470	COG3118	belongs to the thioredoxin family
D082_RS03475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D082_RS03485	COG0494	nUDIX hydrolase
D082_RS03490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D082_RS03495	COG0194	GDP metabolic process
D082_RS03500	COG0406	alpha-ribazole phosphatase activity
D082_RS03520	COG0714	Associated with various cellular activities
D082_RS03525	COG0305	Participates in initiation and elongation during chromosome replication
D082_RS03525	COG1372	Participates in initiation and elongation during chromosome replication
D082_RS03535	COG1842	Phage shock protein A
D082_RS03545	COG5002	protein histidine kinase activity
D082_RS03555	COG1596	polysaccharide export
D082_RS03565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D082_RS03580	COG2385	sporulation resulting in formation of a cellular spore
D082_RS03590	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
D082_RS03620	COG1032	radical SAM domain protein
D082_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS03635	COG3548	integral membrane protein
D082_RS03645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D082_RS03650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D082_RS03655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D082_RS03660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D082_RS03665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D082_RS03670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D082_RS03675	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D082_RS03680	COG5398	heme oxygenase
D082_RS03685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D082_RS03695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D082_RS03700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D082_RS03715	COG2197	response regulator
D082_RS03720	COG3437	response regulator, receiver
D082_RS03725	COG1122	ATPase activity
D082_RS03730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D082_RS03745	COG1842	Phage shock protein A
D082_RS03755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D082_RS03780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D082_RS03785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D082_RS03790	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D082_RS03795	COG0116	Belongs to the methyltransferase superfamily
D082_RS03800	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D082_RS03810	COG2119	membrane
D082_RS03815	COG0653	protein targeting
D082_RS03825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D082_RS03830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D082_RS03840	COG0758	DNA mediated transformation
D082_RS03840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D082_RS03845	COG0393	Putative heavy-metal-binding
D082_RS03855	COG0450	alkyl hydroperoxide reductase
D082_RS03860	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D082_RS03875	COG1175	transmembrane transport
D082_RS03885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D082_RS03935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D082_RS03940	COG1116	anion transmembrane transporter activity
D082_RS03945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D082_RS03945	COG1116	anion transmembrane transporter activity
D082_RS03950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D082_RS03955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D082_RS03960	COG0583	DNA-binding transcription factor activity
D082_RS03965	COG0857	belongs to the CobB CobQ family
D082_RS03980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D082_RS03990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D082_RS03995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D082_RS04005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D082_RS04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D082_RS04015	COG1132	(ABC) transporter
D082_RS04025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D082_RS04030	COG1132	(ABC) transporter
D082_RS04045	COG0811	peptide transport
D082_RS04050	COG0848	biopolymer transport protein
D082_RS04060	COG2226	methyltransferase
D082_RS04065	COG2207	Transcriptional regulator
D082_RS04075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D082_RS04080	COG1120	ATPase activity
D082_RS04095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D082_RS04105	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D082_RS04110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D082_RS04125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D082_RS04130	COG0629	single-stranded DNA binding
D082_RS04150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D082_RS04170	COG0469	pyruvate kinase activity
D082_RS04175	COG1672	PFAM Archaeal ATPase
D082_RS04180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D082_RS04190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D082_RS04210	COG0556	nucleotide-excision repair
D082_RS04235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D082_RS04245	COG0525	valine-tRNA ligase activity
D082_RS04250	COG5002	protein histidine kinase activity
D082_RS04260	COG0728	peptidoglycan biosynthetic process
D082_RS04265	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D082_RS04285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D082_RS04295	COG4636	protein conserved in cyanobacteria
D082_RS04300	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D082_RS04305	COG0557	exoribonuclease II activity
D082_RS04310	COG0784	Response regulator, receiver
D082_RS04325	COG2203	Gaf domain
D082_RS04325	COG0840	transmembrane signaling receptor activity
D082_RS04330	COG0643	Histidine kinase
D082_RS04330	COG0784	Response regulator, receiver
D082_RS04330	COG2198	Histidine kinase
D082_RS04350	COG2954	triphosphatase activity
D082_RS04365	COG0617	tRNA 3'-terminal CCA addition
D082_RS04375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D082_RS04390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D082_RS04400	COG1959	2 iron, 2 sulfur cluster binding
D082_RS04405	COG5001	Diguanylate cyclase
D082_RS04405	COG2203	Gaf domain
D082_RS04405	COG4251	negative regulation of phosphorylation
D082_RS04405	COG3706	GGDEF domain
D082_RS04415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D082_RS04425	COG0357	Ribosomal RNA small subunit methyltransferase G
D082_RS04440	COG0719	Fe-S assembly protein
D082_RS04445	COG0396	ATPase activity
D082_RS04450	COG0719	Fe-S assembly protein
D082_RS04455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D082_RS04460	COG0003	Pfam Anion-transporting ATPase
D082_RS04645	COG0523	cobalamin synthesis protein
D082_RS04650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D082_RS04655	COG1121	(ABC) transporter
D082_RS04660	COG0803	Belongs to the bacterial solute-binding protein 9 family
D082_RS04695	COG1615	UPF0182 protein
D082_RS04710	COG1166	arginine decarboxylase activity
D082_RS04720	COG0587	DNA-directed DNA polymerase activity
D082_RS04725	COG0390	transport system, permease component
D082_RS04730	COG0571	ribonuclease III activity
D082_RS04745	COG3850	Histidine kinase
D082_RS04745	COG4999	Histidine kinase
D082_RS04745	COG3437	response regulator, receiver
D082_RS04745	COG2205	protein histidine kinase activity
D082_RS04755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D082_RS04780	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D082_RS04785	COG2852	Protein conserved in bacteria
D082_RS04790	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
D082_RS04800	COG1543	Belongs to the glycosyl hydrolase 57 family
D082_RS04815	COG5001	Diguanylate cyclase
D082_RS04815	COG1716	ATPase activity
D082_RS04825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D082_RS04830	COG1494	fructose-1,6-bisphosphatase
D082_RS04855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D082_RS04855	COG0519	Catalyzes the synthesis of GMP from XMP
D082_RS04865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D082_RS04875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D082_RS04880	COG0280	phosphate acetyltransferase
D082_RS04880	COG0857	belongs to the CobB CobQ family
D082_RS04885	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS04890	COG1045	serine acetyltransferase
D082_RS04895	COG0288	reversible hydration of carbon dioxide
D082_RS04900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D082_RS04900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D082_RS04905	COG0459	protein refolding
D082_RS04910	COG1131	(ABC) transporter
D082_RS04945	COG2208	phosphoserine phosphatase activity
D082_RS04945	COG2770	Histidine kinase
D082_RS04960	COG1366	Belongs to the anti-sigma-factor antagonist family
D082_RS04985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D082_RS05000	COG1082	Xylose isomerase domain protein TIM barrel
D082_RS05005	COG0596	Alpha beta hydrolase
D082_RS05020	COG2319	Wd-40 repeat
D082_RS05025	COG2319	Wd-40 repeat
D082_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS05040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D082_RS05050	COG0137	argininosuccinate synthase activity
D082_RS05055	COG1064	alcohol dehydrogenase
D082_RS05060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D082_RS05095	COG0702	epimerase
D082_RS05100	COG0326	Molecular chaperone. Has ATPase activity
D082_RS05105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D082_RS05120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D082_RS05125	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D082_RS05130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D082_RS05140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D082_RS05145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D082_RS05160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D082_RS05185	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D082_RS05190	COG1122	ATPase activity
D082_RS05200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D082_RS05215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D082_RS05215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D082_RS05220	COG0848	biopolymer transport protein
D082_RS05225	COG0811	peptide transport
D082_RS05230	COG0529	Catalyzes the synthesis of activated sulfate
D082_RS05240	COG0737	Belongs to the 5'-nucleotidase family
D082_RS05250	COG0745	RESPONSE REGULATOR receiver
D082_RS05255	COG0004	ammonium transporteR
D082_RS05260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D082_RS05265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D082_RS05275	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D082_RS05290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D082_RS05310	COG0515	serine threonine protein kinase
D082_RS05315	COG4658	electron transport chain
D082_RS05350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D082_RS05355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D082_RS05360	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D082_RS05370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D082_RS05385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D082_RS05415	COG0107	imidazoleglycerol-phosphate synthase activity
D082_RS05425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D082_RS05425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D082_RS05435	COG3631	Ketosteroid isomerase-related protein
D082_RS05440	COG1716	ATPase activity
D082_RS05440	COG5001	Diguanylate cyclase
D082_RS05450	COG0386	Belongs to the glutathione peroxidase family
D082_RS05455	COG2119	membrane
D082_RS05465	COG0371	Dehydrogenase
D082_RS05470	COG0644	oxidoreductase
D082_RS05480	COG0438	transferase activity, transferring glycosyl groups
D082_RS05485	COG2046	Belongs to the sulfate adenylyltransferase family
D082_RS05490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D082_RS05495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D082_RS05500	COG0438	transferase activity, transferring glycosyl groups
D082_RS05545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D082_RS05555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D082_RS05560	COG0438	transferase activity, transferring glycosyl groups
D082_RS05565	COG0742	ribosomal rna small subunit methyltransferase
D082_RS05570	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
D082_RS05590	COG0271	Belongs to the BolA IbaG family
D082_RS05595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D082_RS05600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D082_RS05605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D082_RS05610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D082_RS05615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D082_RS05620	COG0443	Heat shock 70 kDa protein
D082_RS05625	COG0628	permease
D082_RS05695	COG1006	Multisubunit Na H antiporter MnhC subunit
D082_RS05700	COG0651	ATP synthesis coupled electron transport
D082_RS05705	COG1006	Multisubunit Na H antiporter MnhC subunit
D082_RS05720	COG0181	hydroxymethylbilane synthase activity
D082_RS05725	COG0427	acetyl-CoA hydrolase
D082_RS05750	COG0557	exoribonuclease II activity
D082_RS05760	COG2208	phosphoserine phosphatase activity
D082_RS05770	COG0165	Argininosuccinate lyase
D082_RS05805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D082_RS05820	COG0438	transferase activity, transferring glycosyl groups
D082_RS05830	COG0500	methyltransferase
D082_RS05915	COG0542	response to heat
D082_RS06055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D082_RS06070	COG1230	cation diffusion facilitator family transporter
D082_RS06075	COG2166	iron-sulfur cluster assembly
D082_RS06080	COG1070	Carbohydrate kinase
D082_RS06115	COG0418	dihydroorotase activity
D082_RS06120	COG2226	methyltransferase
D082_RS06135	COG1672	PFAM Archaeal ATPase
D082_RS06135	COG2319	Wd-40 repeat
D082_RS06145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D082_RS06150	COG4372	Transposase
D082_RS06160	COG0442	prolyl-tRNA aminoacylation
D082_RS06170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D082_RS06180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D082_RS06210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D082_RS06215	COG0473	3-isopropylmalate dehydrogenase activity
D082_RS06225	COG1575	Belongs to the MenA family. Type 1 subfamily
D082_RS06235	COG0656	L-ascorbic acid biosynthetic process
D082_RS06240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D082_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D082_RS06250	COG0416	fatty acid biosynthetic process
D082_RS06260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D082_RS06265	COG0438	transferase activity, transferring glycosyl groups
D082_RS06275	COG0459	protein refolding
D082_RS06280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D082_RS06285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D082_RS06295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D082_RS06310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D082_RS06320	COG0398	Pfam SNARE associated Golgi protein
D082_RS06330	COG2226	methyltransferase
D082_RS06335	COG3706	GGDEF domain
D082_RS06340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D082_RS06340	COG0574	Belongs to the PEP-utilizing enzyme family
D082_RS06345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D082_RS06345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D082_RS06365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D082_RS06385	COG0105	UTP biosynthetic process
D082_RS06395	COG0318	PFAM AMP-dependent synthetase and ligase
D082_RS06405	COG0784	Response regulator, receiver
D082_RS06410	COG4251	negative regulation of phosphorylation
D082_RS06420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D082_RS06435	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS06440	COG0183	Belongs to the thiolase family
D082_RS06450	COG0386	Belongs to the glutathione peroxidase family
D082_RS06465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D082_RS06470	COG2264	protein methyltransferase activity
D082_RS06480	COG1309	transcriptional regulator
D082_RS06490	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D082_RS06495	COG5002	protein histidine kinase activity
D082_RS06500	COG0489	protein tyrosine kinase activity
D082_RS06505	COG0612	Peptidase, M16
D082_RS06510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D082_RS06510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D082_RS06555	COG4636	protein conserved in cyanobacteria
D082_RS06575	COG0667	Aldo Keto reductase
D082_RS06580	COG0628	permease
D082_RS06590	COG1051	belongs to the nudix hydrolase family
D082_RS06590	COG1056	cytidyltransferase-related domain
D082_RS06635	COG1231	oxidoreductase activity
D082_RS06650	COG0277	FAD linked oxidase domain protein
D082_RS06670	COG0066	3-isopropylmalate dehydratase activity
D082_RS06675	COG0504	CTP synthase activity
D082_RS06720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D082_RS06725	COG0740	serine-type endopeptidase activity
D082_RS06730	COG0740	serine-type endopeptidase activity
D082_RS06735	COG3038	cytochrome b561
D082_RS06745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D082_RS06765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D082_RS06785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D082_RS06795	COG0765	amino acid transport
D082_RS06800	COG3659	wide pore channel activity
D082_RS06815	COG0310	cobalt ion transport
D082_RS06825	COG1122	ATPase activity
D082_RS06835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D082_RS06845	COG0589	response to stress
D082_RS06845	COG0475	glutathione-regulated potassium exporter activity
D082_RS06855	COG0406	alpha-ribazole phosphatase activity
D082_RS06865	COG1104	cysteine desulfurase activity
D082_RS06875	COG1376	ErfK ybiS ycfS ynhG family protein
D082_RS06890	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D082_RS06900	COG3659	wide pore channel activity
D082_RS06905	COG0477	Major facilitator Superfamily
D082_RS06910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D082_RS06915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D082_RS06920	COG0668	transmembrane transport
D082_RS06930	COG0745	RESPONSE REGULATOR receiver
D082_RS06935	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D082_RS06935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D082_RS06940	COG3937	granule-associated protein
D082_RS06955	COG2226	methyltransferase
D082_RS06965	COG0681	Belongs to the peptidase S26 family
D082_RS06975	COG1271	oxidase subunit
D082_RS06980	COG1294	oxidase, subunit
D082_RS06985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D082_RS06990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D082_RS06995	COG0412	Dienelactone hydrolase
D082_RS07015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D082_RS07020	COG0725	ABC transporter, periplasmic molybdate-binding protein
D082_RS07040	COG2304	oxidoreductase activity
D082_RS07050	COG1192	Involved in chromosome partitioning
D082_RS07065	COG1473	amidohydrolase
D082_RS07075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D082_RS07090	COG0148	phosphopyruvate hydratase activity
D082_RS07095	COG0457	Tetratricopeptide repeat
D082_RS07100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D082_RS07105	COG0018	arginyl-trna synthetase
D082_RS07120	COG1160	GTP binding
D082_RS07125	COG0019	diaminopimelate decarboxylase activity
D082_RS07130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D082_RS07135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D082_RS07140	COG0598	Magnesium transport protein CorA
D082_RS07200	COG4581	dead DEAH box helicase
D082_RS07220	COG1104	cysteine desulfurase activity
D082_RS07245	COG0582	viral genome integration into host DNA
D082_RS07255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D082_RS07255	COG2022	thiamine diphosphate biosynthetic process
D082_RS07315	COG3604	Transcriptional regulator
D082_RS07350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D082_RS07360	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D082_RS07370	COG3237	CsbD-like
D082_RS07380	COG3237	CsbD-like
D082_RS07390	COG5635	Nacht domain
D082_RS07390	COG2319	Wd-40 repeat
D082_RS07400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D082_RS07415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D082_RS07435	COG0025	NhaP-type Na H and K H
D082_RS07460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D082_RS07470	COG0384	phenazine biosynthesis protein PhzF
D082_RS07495	COG0534	Mate efflux family protein
D082_RS07500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D082_RS07510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D082_RS07520	COG0762	integral membrane protein
D082_RS07530	COG0426	domain, Protein
D082_RS07530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D082_RS07535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D082_RS07545	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D082_RS07565	COG0678	peroxiredoxin activity
D082_RS07575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D082_RS07580	COG2197	response regulator
D082_RS07590	COG2197	response regulator
D082_RS07595	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D082_RS07610	COG0205	6-phosphofructokinase activity
D082_RS07630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D082_RS07630	COG0674	pyruvate-flavodoxin oxidoreductase activity
D082_RS07630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D082_RS07630	COG1013	pyruvate-flavodoxin oxidoreductase activity
D082_RS07650	COG0793	Belongs to the peptidase S41A family
D082_RS07655	COG0009	L-threonylcarbamoyladenylate synthase
D082_RS07660	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
D082_RS07665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D082_RS07670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D082_RS07680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D082_RS07685	COG2205	protein histidine kinase activity
D082_RS07690	COG0012	GTP binding
D082_RS07725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D082_RS07735	COG1640	4-alpha-glucanotransferase
D082_RS07740	COG2715	membrane protein required for spore maturation
D082_RS07750	COG2010	Cytochrome c
D082_RS07755	COG0359	binds to the 23S rRNA
D082_RS07765	COG1032	radical SAM domain protein
D082_RS07790	COG0298	carbon dioxide binding
D082_RS07795	COG0109	protoheme IX farnesyltransferase activity
D082_RS07800	COG1612	heme a metabolic process
D082_RS07805	COG2197	response regulator
D082_RS07820	COG1132	(ABC) transporter
D082_RS07835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D082_RS07840	COG0672	)-iron permease
D082_RS07845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D082_RS07850	COG2255	four-way junction helicase activity
D082_RS07855	COG2022	thiamine diphosphate biosynthetic process
D082_RS07855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D082_RS07860	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
D082_RS07870	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D082_RS07875	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D082_RS07895	COG0697	spore germination
D082_RS07925	COG0583	DNA-binding transcription factor activity
D082_RS07965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D082_RS07975	COG3063	Type IV pilus biogenesis stability protein PilW
D082_RS07980	COG2217	Heavy metal translocating P-type atpase
D082_RS07985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D082_RS07990	COG0745	RESPONSE REGULATOR receiver
D082_RS08000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D082_RS08005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D082_RS08015	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D082_RS08025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D082_RS08035	COG1489	DNA binding
D082_RS08050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D082_RS08055	COG0222	ribosome binding
D082_RS08060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D082_RS08065	COG0081	regulation of translation
D082_RS08070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D082_RS08075	COG0250	Participates in transcription elongation, termination and antitermination
D082_RS08080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D082_RS08090	COG0335	large ribosomal subunit rRNA binding
D082_RS08100	COG0596	Alpha beta hydrolase
D082_RS08120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D082_RS08125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D082_RS08130	COG2203	Gaf domain
D082_RS08130	COG5001	Diguanylate cyclase
D082_RS08130	COG3706	GGDEF domain
D082_RS08130	COG4251	negative regulation of phosphorylation
D082_RS08150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D082_RS08160	COG1214	PFAM Peptidase M22, glycoprotease
D082_RS08175	COG2133	pyrroloquinoline quinone binding
D082_RS08180	COG1797	cobyrinic acid a,c-diamide synthase activity
D082_RS08185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D082_RS08190	COG1022	Amp-dependent synthetase and ligase
D082_RS08195	COG0784	Response regulator, receiver
D082_RS08210	COG0840	transmembrane signaling receptor activity
D082_RS08210	COG2203	Gaf domain
D082_RS08215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D082_RS08220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D082_RS08225	COG5001	Diguanylate cyclase
D082_RS08225	COG3706	GGDEF domain
D082_RS08225	COG2203	Gaf domain
D082_RS08225	COG4251	negative regulation of phosphorylation
D082_RS08230	COG0419	ATPase involved in DNA repair
D082_RS08235	COG0484	heat shock protein binding
D082_RS08240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D082_RS08250	COG2314	TM2 domain
D082_RS08270	COG0017	Asparaginyl-tRNA synthetase
D082_RS08295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D082_RS08305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D082_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS08330	COG2197	response regulator
D082_RS08335	COG4251	negative regulation of phosphorylation
D082_RS08335	COG5001	Diguanylate cyclase
D082_RS08335	COG2203	Gaf domain
D082_RS08335	COG3706	GGDEF domain
D082_RS08345	COG0589	response to stress
D082_RS08360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D082_RS08365	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS08365	COG0515	serine threonine protein kinase
D082_RS08370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D082_RS08370	COG0072	phenylalanine-tRNA ligase activity
D082_RS08380	COG0784	Response regulator, receiver
D082_RS08385	COG4251	negative regulation of phosphorylation
D082_RS08385	COG3706	GGDEF domain
D082_RS08385	COG2203	Gaf domain
D082_RS08385	COG5001	Diguanylate cyclase
D082_RS08390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D082_RS08390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D082_RS08400	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D082_RS08410	COG0745	RESPONSE REGULATOR receiver
D082_RS08415	COG1304	FMN binding
D082_RS08425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D082_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
D082_RS08455	COG0346	lactoylglutathione lyase activity
D082_RS08470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D082_RS08475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D082_RS08480	COG0237	dephospho-CoA kinase activity
D082_RS08485	COG0237	dephospho-CoA kinase activity
D082_RS08515	COG0515	serine threonine protein kinase
D082_RS08525	COG2988	succinylglutamate desuccinylase activity
D082_RS08530	COG1473	amidohydrolase
D082_RS08535	COG0170	dolichyl monophosphate biosynthetic process
D082_RS08540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D082_RS08550	COG0517	IMP dehydrogenase activity
D082_RS08550	COG0617	tRNA 3'-terminal CCA addition
D082_RS08550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D082_RS08570	COG0058	SHG alpha-glucan phosphorylase activity
D082_RS08580	COG0575	Belongs to the CDS family
D082_RS08590	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D082_RS08605	COG0752	glycyl-tRNA synthetase alpha subunit
D082_RS08610	COG0668	transmembrane transport
D082_RS08615	COG5002	protein histidine kinase activity
D082_RS08620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D082_RS08630	COG1597	lipid kinase activity
D082_RS08640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D082_RS08665	COG2385	sporulation resulting in formation of a cellular spore
D082_RS08670	COG0649	NAD binding
D082_RS08685	COG0429	hydrolase of the alpha beta-hydrolase fold
D082_RS08695	COG2154	pterin-4-alpha-carbinolamine dehydratase
D082_RS08705	COG0592	DNA-directed DNA polymerase activity
D082_RS08710	COG0159	tryptophan synthase activity
D082_RS08725	COG0436	Aminotransferase
D082_RS08735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D082_RS08755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D082_RS08760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D082_RS08775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D082_RS08785	COG5398	heme oxygenase
D082_RS08790	COG0408	coproporphyrinogen oxidase activity
D082_RS08800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D082_RS08840	COG0494	nUDIX hydrolase
D082_RS08845	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D082_RS08850	COG0039	L-malate dehydrogenase activity
D082_RS08865	COG0193	aminoacyl-tRNA hydrolase activity
D082_RS08900	COG0024	Methionine aminopeptidase
D082_RS08905	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
D082_RS08910	COG0596	Alpha beta hydrolase
D082_RS08920	COG4243	Vitamin k epoxide reductase
D082_RS08925	COG0426	domain, Protein
D082_RS08925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D082_RS08940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D082_RS08960	COG0539	negative regulation of cytoplasmic translation
D082_RS08965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D082_RS08970	COG1132	(ABC) transporter
D082_RS08975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D082_RS08980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D082_RS08985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D082_RS08990	COG0167	dihydroorotate dehydrogenase activity
D082_RS08995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D082_RS09005	COG1748	Saccharopine dehydrogenase
D082_RS09045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D082_RS09050	COG0745	RESPONSE REGULATOR receiver
D082_RS09055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D082_RS09065	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D082_RS09090	COG1902	pentaerythritol trinitrate reductase activity
D082_RS09100	COG0300	oxidoreductase activity
D082_RS09115	COG4991	sh3 domain protein
D082_RS09115	COG0515	serine threonine protein kinase
D082_RS09115	COG3064	Membrane
D082_RS09130	COG0515	serine threonine protein kinase
D082_RS09130	COG4991	sh3 domain protein
D082_RS09130	COG3064	Membrane
D082_RS09155	COG1217	gtp-binding protein TYPA
D082_RS09165	COG5001	Diguanylate cyclase
D082_RS09165	COG1716	ATPase activity
D082_RS09175	COG0589	response to stress
D082_RS09185	COG0163	prenyltransferase activity
D082_RS09200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D082_RS09205	COG0297	glycogen (starch) synthase activity
D082_RS09210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D082_RS09225	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
D082_RS09230	COG0303	'Molybdopterin
D082_RS09235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D082_RS09240	COG0315	cyclic pyranopterin monophosphate synthase activity
D082_RS09240	COG0746	molybdenum cofactor guanylyltransferase activity
D082_RS09250	COG0314	molybdopterin synthase activity
D082_RS09255	COG0157	Belongs to the NadC ModD family
D082_RS09270	COG2082	Precorrin-8x methylmutase
D082_RS09275	COG0612	Peptidase, M16
D082_RS09280	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D082_RS09295	COG0656	L-ascorbic acid biosynthetic process
D082_RS09300	COG3588	fructose-bisphosphate aldolase
D082_RS09320	COG4191	Histidine kinase
D082_RS09320	COG0784	Response regulator, receiver
D082_RS09335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D082_RS09340	COG1530	ribonuclease E activity
D082_RS09350	COG0330	HflC and HflK could
D082_RS09370	COG2099	Precorrin-6x reductase
D082_RS09400	COG0569	domain protein
D082_RS09405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D082_RS09410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D082_RS09415	COG0629	single-stranded DNA binding
D082_RS09425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D082_RS09440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D082_RS09445	COG0484	heat shock protein binding
D082_RS09460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D082_RS09465	COG0003	Pfam Anion-transporting ATPase
D082_RS09475	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D082_RS09480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D082_RS09490	COG1420	regulation of RNA biosynthetic process
D082_RS09495	COG0175	sulfate reduction
D082_RS09500	COG1981	membrane
D082_RS09510	COG0745	RESPONSE REGULATOR receiver
D082_RS09515	COG0385	Bile acid
D082_RS09525	COG0776	regulation of translation
D082_RS09540	COG0514	ATP-dependent DNA helicase (RecQ)
D082_RS09555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D082_RS09565	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D082_RS09570	COG0701	Predicted permease
D082_RS09590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D082_RS09595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D082_RS09600	COG4636	protein conserved in cyanobacteria
D082_RS09605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D082_RS09625	COG0489	protein tyrosine kinase activity
D082_RS09625	COG3206	protein involved in exopolysaccharide biosynthesis
D082_RS09650	COG1132	(ABC) transporter
D082_RS09670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D082_RS09700	COG0110	maltose O-acetyltransferase activity
D082_RS09725	COG0463	Glycosyl transferase, family 2
D082_RS09770	COG1216	Glycosyl transferase, family 2
D082_RS09775	COG0438	transferase activity, transferring glycosyl groups
D082_RS09780	COG0275	rRNA processing
D082_RS09805	COG0438	transferase activity, transferring glycosyl groups
D082_RS09815	COG0438	transferase activity, transferring glycosyl groups
D082_RS09835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D082_RS09840	COG0110	maltose O-acetyltransferase activity
D082_RS09860	COG3264	Mechanosensitive ion channel
D082_RS09860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D082_RS09865	COG2052	Domain of unknown function (DUF370)
D082_RS09870	COG1496	oxidoreductase activity
D082_RS09875	COG2226	methyltransferase
D082_RS09880	COG3185	4-Hydroxyphenylpyruvate dioxygenase
D082_RS09885	COG1012	belongs to the aldehyde dehydrogenase family
D082_RS09890	COG1216	Glycosyl transferase, family 2
D082_RS09895	COG0484	heat shock protein binding
D082_RS09905	COG0659	secondary active sulfate transmembrane transporter activity
D082_RS09935	COG1970	mechanosensitive ion channel activity
D082_RS09940	COG0632	four-way junction helicase activity
D082_RS09945	COG1836	PFAM Integral membrane protein DUF92
D082_RS09950	COG0446	pyridine nucleotide-disulphide oxidoreductase
D082_RS09955	COG0724	RNA recognition motif
D082_RS09960	COG0154	amidase activity
D082_RS09965	COG0739	heme binding
D082_RS09970	COG0509	glycine decarboxylation via glycine cleavage system
D082_RS09975	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D082_RS10010	COG1316	TRANSCRIPTIONal
D082_RS10020	COG3706	GGDEF domain
D082_RS10020	COG4251	negative regulation of phosphorylation
D082_RS10020	COG5001	Diguanylate cyclase
D082_RS10020	COG2203	Gaf domain
D082_RS10025	COG0659	secondary active sulfate transmembrane transporter activity
D082_RS10030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D082_RS10040	COG0457	Tetratricopeptide repeat
D082_RS10045	COG1160	GTP binding
D082_RS10060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D082_RS10070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D082_RS10075	COG0052	Belongs to the universal ribosomal protein uS2 family
D082_RS10085	COG0174	glutamine synthetase
D082_RS10090	COG1247	-acetyltransferase
D082_RS10095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D082_RS10145	COG0454	-acetyltransferase
D082_RS10150	COG0737	Belongs to the 5'-nucleotidase family
D082_RS10170	COG1233	COG1233 Phytoene dehydrogenase and related
D082_RS10175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D082_RS10180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D082_RS10185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D082_RS10195	COG0515	serine threonine protein kinase
D082_RS10220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D082_RS10220	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
D082_RS10225	COG1562	ergosterol biosynthetic process
D082_RS10230	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D082_RS10235	COG0831	urea catabolic process
D082_RS10245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D082_RS10250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D082_RS10260	COG2066	Belongs to the glutaminase family
D082_RS10270	COG0222	ribosome binding
D082_RS10280	COG0745	RESPONSE REGULATOR receiver
D082_RS10295	COG1192	Involved in chromosome partitioning
D082_RS10300	COG0784	Response regulator, receiver
D082_RS10300	COG2205	protein histidine kinase activity
D082_RS10305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D082_RS10320	COG3339	Conserved Protein
D082_RS10325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D082_RS10330	COG0572	uridine kinase
D082_RS10335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D082_RS10340	COG0561	phosphatase activity
D082_RS10350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D082_RS10390	COG1131	(ABC) transporter
D082_RS10400	COG2048	Heterodisulfide reductase, subunit B
D082_RS10415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D082_RS10420	COG0121	glutamine amidotransferase
D082_RS10435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D082_RS10445	COG1252	NADH dehydrogenase
D082_RS10460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D082_RS10480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D082_RS10485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D082_RS10500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D082_RS10505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D082_RS10510	COG0581	inorganic phosphate transmembrane transporter activity
D082_RS10520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D082_RS10525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D082_RS10540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D082_RS10550	COG1595	DNA-templated transcription, initiation
D082_RS10565	COG0415	Belongs to the DNA photolyase family
D082_RS10585	COG4948	Mandelate Racemase Muconate Lactonizing
D082_RS10590	COG0824	Thioesterase
D082_RS10595	COG4399	Belongs to the UPF0754 family
D082_RS10620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D082_RS10630	COG1234	tRNA 3'-trailer cleavage
D082_RS10635	COG2358	TRAP transporter, solute receptor (TAXI family
D082_RS10655	COG0460	homoserine dehydrogenase
D082_RS10660	COG2091	lysine biosynthetic process via aminoadipic acid
D082_RS10670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D082_RS10710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D082_RS10735	COG4447	cellulose binding
D082_RS10740	COG1773	rubredoxin
D082_RS10745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D082_RS10760	COG0803	Belongs to the bacterial solute-binding protein 9 family
D082_RS10765	COG1121	(ABC) transporter
D082_RS10770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D082_RS10825	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D082_RS10825	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
D082_RS10830	COG0439	Biotin carboxylase
D082_RS10840	COG0590	tRNA wobble adenosine to inosine editing
D082_RS10845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D082_RS10850	COG0024	Methionine aminopeptidase
D082_RS10855	COG0156	8-amino-7-oxononanoate synthase activity
D082_RS10865	COG1982	Orn Lys Arg decarboxylase major
D082_RS10870	COG0686	Belongs to the AlaDH PNT family
D082_RS10875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D082_RS10895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D082_RS10905	COG0497	DNA recombination
D082_RS10915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D082_RS10925	COG1253	flavin adenine dinucleotide binding
D082_RS10935	COG0083	homoserine kinase activity
D082_RS10940	COG1196	nuclear chromosome segregation
D082_RS10955	COG0284	orotidine-5'-phosphate decarboxylase activity
D082_RS10995	COG1162	GTPase activity
D082_RS11020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D082_RS11025	COG0375	protein maturation
D082_RS11040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D082_RS11045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D082_RS11050	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
D082_RS11065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D082_RS11075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D082_RS11090	COG0662	Cupin 2, conserved barrel domain protein
D082_RS11090	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
D082_RS11100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D082_RS11105	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D082_RS11110	COG0237	dephospho-CoA kinase activity
D082_RS11110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D082_RS11135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS11145	COG0516	GMP reductase activity
D082_RS11145	COG0517	IMP dehydrogenase activity
D082_RS11155	COG1937	Protein conserved in bacteria
D082_RS11165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D082_RS11175	COG4257	antibiotic catabolic process
D082_RS11185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D082_RS11190	COG0443	Heat shock 70 kDa protein
D082_RS11195	COG0484	heat shock protein binding
D082_RS11210	COG1587	Uroporphyrinogen-III synthase
D082_RS11215	COG2319	Wd-40 repeat
D082_RS11260	COG0205	6-phosphofructokinase activity
D082_RS11265	COG0336	Belongs to the RNA methyltransferase TrmD family
D082_RS11275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D082_RS11280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D082_RS11285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D082_RS11305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D082_RS11310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D082_RS11315	COG0254	rRNA binding
D082_RS11320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D082_RS11325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D082_RS11330	COG0101	tRNA pseudouridine synthase activity
D082_RS11335	COG0203	ribosomal protein L17
D082_RS11340	COG0202	RNA polymerase activity
D082_RS11345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D082_RS11350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D082_RS11355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D082_RS11360	COG0563	adenylate kinase activity
D082_RS11365	COG0201	protein transport
D082_RS11370	COG0200	Binds to the 23S rRNA
D082_RS11375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D082_RS11380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D082_RS11385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D082_RS11390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D082_RS11395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D082_RS11400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D082_RS11405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D082_RS11410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D082_RS11415	COG0255	Belongs to the universal ribosomal protein uL29 family
D082_RS11420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D082_RS11425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D082_RS11430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D082_RS11435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D082_RS11440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D082_RS11445	COG0089	rRNA binding
D082_RS11450	COG0088	Forms part of the polypeptide exit tunnel
D082_RS11455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D082_RS11460	COG0783	Belongs to the Dps family
D082_RS11525	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D082_RS11535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D082_RS11540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D082_RS11545	COG0513	Belongs to the DEAD box helicase family
D082_RS11550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D082_RS11555	COG0745	RESPONSE REGULATOR receiver
D082_RS11580	COG2308	Evidence 4 Homologs of previously reported genes of
D082_RS11585	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D082_RS11590	COG5002	protein histidine kinase activity
D082_RS11595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D082_RS11600	COG0443	Heat shock 70 kDa protein
D082_RS11610	COG0616	signal peptide processing
D082_RS11630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D082_RS11635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D082_RS11640	COG0436	Aminotransferase
D082_RS11660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D082_RS11670	COG0195	Participates in both transcription termination and antitermination
D082_RS11675	COG0779	Required for maturation of 30S ribosomal subunits
D082_RS11680	COG0704	Plays a role in the regulation of phosphate uptake
D082_RS11700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D082_RS11710	COG5002	protein histidine kinase activity
D082_RS11720	COG1192	Involved in chromosome partitioning
D082_RS11750	COG3228	Belongs to the MtfA family
D082_RS11755	COG4999	Histidine kinase
D082_RS11755	COG3850	Histidine kinase
D082_RS11755	COG3437	response regulator, receiver
D082_RS11755	COG2205	protein histidine kinase activity
D082_RS11760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D082_RS11775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D082_RS11780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D082_RS11785	COG0720	synthase
D082_RS11800	COG0328	RNA-DNA hybrid ribonuclease activity
D082_RS11805	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D082_RS11810	COG0085	RNA polymerase activity
D082_RS11815	COG0084	hydrolase, TatD family'
D082_RS11820	COG0268	Binds directly to 16S ribosomal RNA
D082_RS11825	COG5002	protein histidine kinase activity
D082_RS11835	COG0210	DNA helicase
D082_RS11835	COG0210	DNA helicase
D082_RS11840	COG3128	pkhd-type hydroxylase
D082_RS11850	COG0113	porphobilinogen synthase activity
D082_RS11860	COG0438	transferase activity, transferring glycosyl groups
D082_RS11870	COG2205	protein histidine kinase activity
D082_RS11870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D082_RS11875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D082_RS11880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D082_RS11885	COG0612	Peptidase, M16
D082_RS11890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D082_RS11895	COG3259	Nickel-dependent hydrogenase
D082_RS11905	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
D082_RS11910	COG1034	ATP synthesis coupled electron transport
D082_RS11940	COG0409	Hydrogenase expression formation protein
D082_RS11945	COG0322	excinuclease ABC activity
D082_RS11960	COG0860	N-Acetylmuramoyl-L-alanine amidase
D082_RS11960	COG3103	Sh3 type 3 domain protein
D082_RS11960	COG3103	Sh3 type 3 domain protein
D082_RS11960	COG4991	sh3 domain protein
D082_RS11960	COG0860	N-Acetylmuramoyl-L-alanine amidase
D082_RS11960	COG4991	sh3 domain protein
D082_RS11980	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D082_RS11990	COG3258	Cytochrome c
D082_RS11995	COG0723	plastoquinol--plastocyanin reductase activity
D082_RS12020	COG0051	transcription antitermination factor activity, RNA binding
D082_RS12025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D082_RS12030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D082_RS12035	COG0049	tRNA binding
D082_RS12040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D082_RS12050	COG0151	Belongs to the GarS family
D082_RS12065	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS12070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D082_RS12080	COG0724	RNA recognition motif
D082_RS12085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D082_RS12090	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D082_RS12110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D082_RS12135	COG4232	protein-disulfide reductase activity
D082_RS12140	COG1595	DNA-templated transcription, initiation
D082_RS12170	COG1132	(ABC) transporter
D082_RS12175	COG0837	glucose binding
D082_RS12185	COG0546	phosphoglycolate phosphatase activity
D082_RS12190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D082_RS12195	COG2193	ferroxidase activity
D082_RS12215	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
D082_RS12230	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D082_RS12235	COG0463	Glycosyl transferase, family 2
D082_RS12240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D082_RS12245	COG1280	lysine exporter protein (LysE YggA)
D082_RS12250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D082_RS12260	COG1472	Belongs to the glycosyl hydrolase 3 family
D082_RS12270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D082_RS12275	COG0583	DNA-binding transcription factor activity
D082_RS12280	COG0126	phosphoglycerate kinase activity
D082_RS12290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D082_RS12295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D082_RS12305	COG0113	porphobilinogen synthase activity
D082_RS12315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D082_RS12325	COG0505	Belongs to the CarA family
D082_RS12330	COG0070	glutamate synthase
D082_RS12330	COG0069	glutamate synthase activity
D082_RS12330	COG0067	glutamate synthase
D082_RS12350	COG4251	negative regulation of phosphorylation
D082_RS12350	COG2203	Gaf domain
D082_RS12350	COG5001	Diguanylate cyclase
D082_RS12350	COG3706	GGDEF domain
D082_RS12360	COG0475	glutathione-regulated potassium exporter activity
D082_RS12390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D082_RS12395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D082_RS12410	COG0549	Belongs to the carbamate kinase family
D082_RS12415	COG4251	negative regulation of phosphorylation
D082_RS12415	COG5001	Diguanylate cyclase
D082_RS12415	COG3706	GGDEF domain
D082_RS12415	COG2203	Gaf domain
D082_RS12445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D082_RS12465	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS12470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D082_RS12475	COG0583	DNA-binding transcription factor activity
D082_RS12480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D082_RS12490	COG0247	lactate metabolic process
D082_RS12500	COG0768	penicillin binding
D082_RS12510	COG0237	dephospho-CoA kinase activity
D082_RS12520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D082_RS12525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D082_RS12530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D082_RS12540	COG0544	peptidyl-prolyl cis-trans isomerase activity
D082_RS12545	COG0740	serine-type endopeptidase activity
D082_RS12550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D082_RS12560	COG0569	domain protein
D082_RS12565	COG0004	ammonium transporteR
D082_RS12570	COG0134	indole-3-glycerol-phosphate synthase activity
D082_RS12575	COG1218	3'(2'),5'-bisphosphate nucleotidase
D082_RS12580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D082_RS12585	COG0484	heat shock protein binding
D082_RS12595	COG1162	GTPase activity
D082_RS12605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D082_RS12610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D082_RS12615	COG2119	membrane
D082_RS12635	COG0515	serine threonine protein kinase
D082_RS12655	COG0138	bifunctional purine biosynthesis protein purh
D082_RS12665	COG2205	protein histidine kinase activity
D082_RS12665	COG2202	Pas domain
D082_RS12670	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D082_RS12685	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D082_RS12690	COG0180	Tryptophanyl-tRNA synthetase
D082_RS12705	COG3659	wide pore channel activity
D082_RS12710	COG0493	'glutamate synthase
D082_RS12715	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS12720	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS12725	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
D082_RS12735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D082_RS12740	COG0631	protein serine/threonine phosphatase activity
D082_RS12750	COG0579	oxidoreductase
D082_RS12760	COG3854	ATPases associated with a variety of cellular activities
D082_RS12765	COG0352	thiamine-phosphate diphosphorylase activity
D082_RS12770	COG0434	BtpA family
D082_RS12795	COG0564	pseudouridine synthase activity
D082_RS12805	COG1741	Belongs to the pirin family
D082_RS12810	COG0583	DNA-binding transcription factor activity
D082_RS12815	COG1193	negative regulation of DNA recombination
D082_RS12825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D082_RS12840	COG3937	granule-associated protein
D082_RS12855	COG1181	Belongs to the D-alanine--D-alanine ligase family
D082_RS12860	COG3932	Exopolysaccharide synthesis, ExoD
D082_RS12865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D082_RS12875	COG0360	Binds together with S18 to 16S ribosomal RNA
D082_RS12880	COG0179	Fumarylacetoacetate (FAA) hydrolase
D082_RS12885	COG1413	lyase activity
D082_RS12890	COG0641	radical SAM
D082_RS12920	COG0196	riboflavin kinase activity
D082_RS12930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS12935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D082_RS12945	COG2885	chlorophyll binding
D082_RS12950	COG2885	chlorophyll binding
D082_RS12960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D082_RS12965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS12975	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D082_RS12985	COG3243	poly(R)-hydroxyalkanoic acid synthase
D082_RS12995	COG0606	chelatase, subunit chli
D082_RS13005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D082_RS13010	COG1716	ATPase activity
D082_RS13015	COG0850	regulation of cytokinetic process
D082_RS13020	COG2894	cell division
D082_RS13025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D082_RS13035	COG0076	glutamate decarboxylase activity
D082_RS13040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D082_RS13045	COG0829	nickel cation binding
D082_RS13060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D082_RS13065	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D082_RS13090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D082_RS13100	COG1834	amidinotransferase
D082_RS13105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D082_RS13110	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
D082_RS13115	COG0129	dihydroxy-acid dehydratase activity
D082_RS13130	COG0463	Glycosyl transferase, family 2
D082_RS13135	COG0505	Belongs to the CarA family
D082_RS13140	COG0740	serine-type endopeptidase activity
D082_RS13145	COG0133	tryptophan synthase activity
D082_RS13155	COG2203	Gaf domain
D082_RS13155	COG5001	Diguanylate cyclase
D082_RS13155	COG4251	negative regulation of phosphorylation
D082_RS13155	COG3706	GGDEF domain
D082_RS13170	COG0387	Pfam Sodium calcium exchanger
D082_RS13175	COG0717	Belongs to the dCTP deaminase family
D082_RS13180	COG0475	glutathione-regulated potassium exporter activity
D082_RS13195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D082_RS13200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D082_RS13205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D082_RS13210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D082_RS13215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D082_RS13220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D082_RS13225	COG0356	it plays a direct role in the translocation of protons across the membrane
D082_RS13240	COG5002	protein histidine kinase activity
D082_RS13250	COG0714	Associated with various cellular activities
D082_RS13255	COG0316	Belongs to the HesB IscA family
D082_RS13260	COG0697	spore germination
D082_RS13270	COG1127	ABC transporter
D082_RS13285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D082_RS13305	COG0004	ammonium transporteR
D082_RS13320	COG1480	7TM receptor with intracellular HD hydrolase
D082_RS13335	COG0347	Belongs to the P(II) protein family
D082_RS13340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D082_RS13380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D082_RS13390	COG3239	Fatty acid desaturase
D082_RS13395	COG0166	Belongs to the GPI family
D082_RS13400	COG0511	ligase activity, forming carbon-carbon bonds
D082_RS13405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D082_RS13410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D082_RS13415	COG0577	efflux transmembrane transporter activity
D082_RS13415	COG1136	(ABC) transporter
D082_RS13420	COG0735	belongs to the Fur family
D082_RS13435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D082_RS13445	COG1410	methionine synthase
D082_RS13445	COG0646	methionine synthase
D082_RS13455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D082_RS13465	COG0784	Response regulator, receiver
D082_RS13465	COG0784	Response regulator, receiver
D082_RS13465	COG0643	Histidine kinase
D082_RS13465	COG2198	Histidine kinase
D082_RS13465	COG0643	Histidine kinase
D082_RS13465	COG2198	Histidine kinase
D082_RS13470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D082_RS13475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D082_RS13490	COG0297	glycogen (starch) synthase activity
D082_RS13505	COG0321	lipoyl(octanoyl) transferase activity
D082_RS13510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D082_RS13520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D082_RS13525	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
D082_RS13530	COG0217	transcriptional regulatory protein
D082_RS13540	COG2217	Heavy metal translocating P-type atpase
D082_RS13550	COG0508	dehydrogenase complex catalyzes the overall conversion of
D082_RS13565	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D082_RS13575	COG0463	Glycosyl transferase, family 2
D082_RS13585	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
D082_RS13590	COG2890	protein-(glutamine-N5) methyltransferase activity
D082_RS13595	COG0312	modulator of DNA gyrase
D082_RS13620	COG1459	type II secretion system
D082_RS13625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D082_RS13635	COG0259	pyridoxamine-phosphate oxidase activity
D082_RS13650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D082_RS13670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D082_RS13675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D082_RS13700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D082_RS13700	COG0189	ligase activity
D082_RS13705	COG4242	Belongs to the peptidase S51 family
D082_RS13715	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D082_RS13715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D082_RS13730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D082_RS13740	COG3239	Fatty acid desaturase
D082_RS13750	COG1950	PFAM Membrane protein of
D082_RS13760	COG1253	flavin adenine dinucleotide binding
D082_RS13765	COG0228	four-way junction DNA binding
D082_RS13785	COG2010	Cytochrome c
D082_RS13800	COG0802	atpase or kinase
D082_RS13805	COG0825	malonyl-CoA metabolic process
D082_RS13835	COG4251	negative regulation of phosphorylation
D082_RS13840	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
D082_RS13850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
D082_RS13855	COG0571	ribonuclease III activity
D082_RS13870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D082_RS13875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D082_RS13890	COG0628	permease
D082_RS13895	COG0149	triose-phosphate isomerase activity
D082_RS13905	COG2205	protein histidine kinase activity
D082_RS13915	COG0070	glutamate synthase
D082_RS13915	COG0067	glutamate synthase
D082_RS13915	COG0069	glutamate synthase activity
D082_RS13950	COG1487	ribonuclease activity
D082_RS13990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D082_RS14000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D082_RS14005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D082_RS14010	COG3659	wide pore channel activity
D082_RS14015	COG1929	Belongs to the glycerate kinase type-1 family
D082_RS14020	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS14025	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
D082_RS14030	COG0022	dehydrogenase e1 component
D082_RS14030	COG0508	dehydrogenase complex catalyzes the overall conversion of
D082_RS14035	COG0745	RESPONSE REGULATOR receiver
D082_RS14055	COG1132	(ABC) transporter
D082_RS14065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D082_RS14080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D082_RS14095	COG1702	phosphate starvation-inducible protein PhoH
D082_RS14100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D082_RS14105	COG1121	(ABC) transporter
D082_RS14120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D082_RS14140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D082_RS14145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D082_RS14150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D082_RS14160	COG2897	thiosulfate sulfurtransferase activity
D082_RS14165	COG0671	phosphoesterase, PA-phosphatase related
D082_RS14170	COG0121	glutamine amidotransferase
D082_RS14195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D082_RS14200	COG0583	DNA-binding transcription factor activity
D082_RS14215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D082_RS14220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D082_RS14225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D082_RS14230	COG4208	sulfate ABC transporter
D082_RS14235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D082_RS14255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D082_RS14270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D082_RS14300	COG1429	ligase activity, forming nitrogen-metal bonds
D082_RS14340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D082_RS14350	COG0242	peptide deformylase activity
D082_RS14355	COG2010	Cytochrome c
D082_RS14365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D082_RS14370	COG0830	nickel cation binding
D082_RS14375	COG0481	GTPase activity
D082_RS14390	COG0277	FAD linked oxidase domain protein
D082_RS14405	COG1131	(ABC) transporter
D082_RS14415	COG1994	Peptidase M50
D082_RS14415	COG0517	IMP dehydrogenase activity
D082_RS14420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D082_RS14455	COG0525	valine-tRNA ligase activity
D082_RS14460	COG0713	ATP synthesis coupled electron transport
D082_RS14465	COG0839	Belongs to the complex I subunit 6 family
D082_RS14470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS14475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D082_RS14485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D082_RS14490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D082_RS14495	COG1845	cytochrome c oxidase, subunit III
D082_RS14500	COG3118	belongs to the thioredoxin family
D082_RS14505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D082_RS14510	COG1116	anion transmembrane transporter activity
D082_RS14515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D082_RS14530	COG0375	protein maturation
D082_RS14535	COG0010	Belongs to the arginase family
D082_RS14550	COG3706	GGDEF domain
D082_RS14555	COG0420	3'-5' exonuclease activity
D082_RS14585	COG1074	ATP-dependent DNA helicase activity
D082_RS14600	COG0495	leucyl-tRNA aminoacylation
D082_RS14605	COG0786	glutamate:sodium symporter activity
D082_RS14615	COG2205	protein histidine kinase activity
D082_RS14635	COG1606	tRNA processing
D082_RS14645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D082_RS14655	COG2045	Belongs to the ComB family
D082_RS14660	COG0778	Nitroreductase
D082_RS14665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D082_RS14675	COG0516	GMP reductase activity
D082_RS14680	COG0395	ABC-type sugar transport system, permease component
D082_RS14690	COG2205	protein histidine kinase activity
D082_RS14705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D082_RS14710	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D082_RS14730	COG2046	Belongs to the sulfate adenylyltransferase family
D082_RS14730	COG0529	Catalyzes the synthesis of activated sulfate
D082_RS14735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D082_RS14745	COG0824	Thioesterase
D082_RS14755	COG4178	(ABC) transporter
D082_RS14760	COG1333	cytochrome c biogenesis protein
D082_RS14765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D082_RS14770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D082_RS14790	COG0436	Aminotransferase
D082_RS14795	COG0372	Belongs to the citrate synthase family
D082_RS14800	COG2062	phosphohistidine phosphatase, SixA
D082_RS14805	COG0596	Alpha beta hydrolase
D082_RS14825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D082_RS14830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D082_RS14835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D082_RS14840	COG0561	phosphatase activity
D082_RS14845	COG1366	Belongs to the anti-sigma-factor antagonist family
D082_RS14850	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D082_RS14855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D082_RS14865	COG0215	cysteine-tRNA ligase activity
D082_RS14870	COG0243	molybdopterin cofactor binding
D082_RS14880	COG1116	anion transmembrane transporter activity
D082_RS14885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D082_RS14885	COG1116	anion transmembrane transporter activity
D082_RS14890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D082_RS14895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D082_RS14900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D082_RS14910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D082_RS14915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D082_RS14925	COG0793	Belongs to the peptidase S41A family
D082_RS14935	COG0275	rRNA processing
D082_RS14945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
D082_RS14955	COG2003	Belongs to the UPF0758 family
D082_RS14960	COG1054	Belongs to the UPF0176 family
D082_RS14985	COG1131	(ABC) transporter
D082_RS14995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D082_RS15005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D082_RS15020	COG0793	Belongs to the peptidase S41A family
D082_RS15025	COG1850	ribulose-bisphosphate carboxylase activity
D082_RS15035	COG4451	ribulose bisphosphate carboxylase, small
D082_RS15050	COG2211	Major facilitator Superfamily
D082_RS15070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D082_RS15080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS15085	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS15090	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D082_RS15095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D082_RS15100	COG0037	tRNA processing
D082_RS15140	COG3659	wide pore channel activity
D082_RS15155	COG0405	Gamma-glutamyltransferase
D082_RS15160	COG0772	Belongs to the SEDS family
D082_RS15170	COG2192	nodulation
D082_RS15175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D082_RS15180	COG2274	protein secretion by the type I secretion system
D082_RS15185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D082_RS15190	COG0723	plastoquinol--plastocyanin reductase activity
D082_RS15200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D082_RS15230	COG0463	Glycosyl transferase, family 2
D082_RS15230	COG0457	Tetratricopeptide repeat
D082_RS15250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D082_RS15265	COG3118	belongs to the thioredoxin family
D082_RS15270	COG2081	HI0933 family
D082_RS15275	COG0469	pyruvate kinase activity
D082_RS15285	COG0135	phosphoribosylanthranilate isomerase activity
D082_RS15290	COG0697	spore germination
D082_RS15295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D082_RS15320	COG2205	protein histidine kinase activity
D082_RS15325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D082_RS15330	COG0750	zinc metalloprotease
D082_RS15345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D082_RS15350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D082_RS15355	COG1357	PFAM Pentapeptide repeats (8 copies)
D082_RS15385	COG1555	photosystem II stabilization
D082_RS15390	COG1289	transmembrane transporter activity
D082_RS15400	COG0590	tRNA wobble adenosine to inosine editing
D082_RS15410	COG0415	Belongs to the DNA photolyase family
D082_RS15420	COG3429	Glucose-6-phosphate dehydrogenase subunit
D082_RS15420	COG3409	Peptidoglycan-binding domain 1 protein
D082_RS15430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D082_RS15450	COG0745	RESPONSE REGULATOR receiver
D082_RS15485	COG1840	ABC-type Fe3 transport system, periplasmic component
D082_RS15495	COG1132	(ABC) transporter
D082_RS15515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D082_RS15520	COG0443	Heat shock 70 kDa protein
D082_RS15525	COG0484	heat shock protein binding
D082_RS15530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D082_RS15540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D082_RS15545	COG0673	inositol 2-dehydrogenase activity
D082_RS15560	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D082_RS15570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D082_RS15585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D082_RS15590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D082_RS15600	COG0189	ligase activity
D082_RS15605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D082_RS15630	COG0402	S-adenosylhomocysteine deaminase activity
D082_RS15660	COG0537	adenosine 5'-monophosphoramidase activity
D082_RS15665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
D082_RS15680	COG0025	NhaP-type Na H and K H
D082_RS15690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D082_RS15730	COG2165	general secretion pathway protein
D082_RS15755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D082_RS15760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D082_RS15765	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D082_RS15780	COG0681	Belongs to the peptidase S26 family
D082_RS15785	COG1185	polyribonucleotide nucleotidyltransferase activity
D082_RS15790	COG0494	nUDIX hydrolase
D082_RS15810	COG0739	heme binding
D082_RS15815	COG1691	(AIR) carboxylase
D082_RS15825	COG2319	Wd-40 repeat
D082_RS15830	COG0154	amidase activity
D082_RS15835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D082_RS15840	COG2226	methyltransferase
D082_RS15845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D082_RS15850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D082_RS15855	COG0730	response to heat
D082_RS15860	COG1413	lyase activity
D082_RS15865	COG1007	ATP synthesis coupled electron transport
D082_RS15880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D082_RS15885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D082_RS15890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D082_RS15895	COG0006	proline dipeptidase activity
D082_RS16025	COG4191	Histidine kinase
D082_RS16160	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D082_RS16680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D082_RS16690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D082_RS16880	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D082_RS16885	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
D082_RS16930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D082_RS17050	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D082_RS17095	COG1657	PFAM Prenyltransferase squalene oxidase
D082_RS17235	COG0616	signal peptide processing
D082_RS17280	COG3328	transposase activity
D082_RS17295	COG3128	pkhd-type hydroxylase
D082_RS17325	COG3063	Type IV pilus biogenesis stability protein PilW
D082_RS17350	COG2911	Protein conserved in bacteria
D082_RS17350	COG1361	Conserved repeat domain
D082_RS17350	COG3266	domain, Protein
D082_RS17360	COG1733	regulation of RNA biosynthetic process
D082_RS17365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D082_RS17385	COG0463	Glycosyl transferase, family 2
D082_RS17385	COG1216	Glycosyl transferase, family 2
D082_RS17390	COG1215	transferase activity, transferring glycosyl groups
D082_RS17420	COG1136	(ABC) transporter
D082_RS17445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA