locus-tag	class	description
SGL_RS00370	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGL_RS00745	COG4774	siderophore transport
SGL_RS01140	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SGL_RS01165	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SGL_RS01190	COG1166	arginine decarboxylase activity
SGL_RS01690	COG4106	trans-aconitate 2-methyltransferase activity
SGL_RS01880	COG1187	pseudouridine synthase activity
SGL_RS01890	COG0515	serine threonine protein kinase
SGL_RS01895	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SGL_RS01900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGL_RS01905	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SGL_RS01915	COG1166	arginine decarboxylase activity
SGL_RS01920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGL_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGL_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGL_RS01940	COG1120	ATPase activity
SGL_RS01945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGL_RS01955	COG4977	sequence-specific DNA binding
SGL_RS01980	COG2207	Transcriptional regulator
SGL_RS01985	COG2226	methyltransferase
SGL_RS01995	COG0848	biopolymer transport protein
SGL_RS02000	COG0811	peptide transport
SGL_RS02015	COG1132	(ABC) transporter
SGL_RS02030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGL_RS02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SGL_RS02045	COG1132	(ABC) transporter
SGL_RS02090	COG0409	Hydrogenase expression formation protein
SGL_RS02095	COG1091	dTDP-4-dehydrorhamnose reductase activity
SGL_RS02100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGL_RS02105	COG0297	glycogen (starch) synthase activity
SGL_RS02120	COG1131	(ABC) transporter
SGL_RS02135	COG2318	DinB family
SGL_RS02140	COG4106	trans-aconitate 2-methyltransferase activity
SGL_RS02155	COG1214	PFAM Peptidase M22, glycoprotease
SGL_RS02175	COG1615	UPF0182 protein
SGL_RS02190	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SGL_RS02195	COG0563	adenylate kinase activity
SGL_RS02200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SGL_RS02220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGL_RS02235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SGL_RS02240	COG0194	GDP metabolic process
SGL_RS02245	COG0406	alpha-ribazole phosphatase activity
SGL_RS02255	COG0730	response to heat
SGL_RS02260	COG1413	lyase activity
SGL_RS02275	COG0330	HflC and HflK could
SGL_RS02280	COG1530	ribonuclease E activity
SGL_RS02285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SGL_RS02290	COG0494	nUDIX hydrolase
SGL_RS02295	COG1185	polyribonucleotide nucleotidyltransferase activity
SGL_RS02300	COG0681	Belongs to the peptidase S26 family
SGL_RS02315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SGL_RS02325	COG1401	restriction endodeoxyribonuclease activity
SGL_RS02330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SGL_RS02335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SGL_RS02380	COG1104	cysteine desulfurase activity
SGL_RS02405	COG0582	viral genome integration into host DNA
SGL_RS02415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGL_RS02415	COG2022	thiamine diphosphate biosynthetic process
SGL_RS02430	COG5002	protein histidine kinase activity
SGL_RS02440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGL_RS02460	COG0704	Plays a role in the regulation of phosphate uptake
SGL_RS02465	COG0779	Required for maturation of 30S ribosomal subunits
SGL_RS02470	COG0195	Participates in both transcription termination and antitermination
SGL_RS02480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGL_RS02520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SGL_RS02530	COG0011	TIGRFAM Protein of
SGL_RS02540	COG0589	response to stress
SGL_RS02545	COG0123	including yeast histone deacetylase and acetoin utilization protein
SGL_RS02550	COG0010	Belongs to the arginase family
SGL_RS02555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGL_RS02595	COG2099	Precorrin-6x reductase
SGL_RS02610	COG1007	ATP synthesis coupled electron transport
SGL_RS02625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SGL_RS02630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGL_RS02635	COG0426	domain, Protein
SGL_RS02635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGL_RS02645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGL_RS02645	COG0426	domain, Protein
SGL_RS02655	COG0793	Belongs to the peptidase S41A family
SGL_RS02660	COG0009	L-threonylcarbamoyladenylate synthase
SGL_RS02665	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SGL_RS02670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SGL_RS02675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SGL_RS02680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGL_RS02685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGL_RS02690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGL_RS02695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGL_RS02700	COG0356	it plays a direct role in the translocation of protons across the membrane
SGL_RS02710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SGL_RS02725	COG0714	Associated with various cellular activities
SGL_RS02730	COG0316	Belongs to the HesB IscA family
SGL_RS02735	COG0697	spore germination
SGL_RS02745	COG1127	ABC transporter
SGL_RS02755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SGL_RS02780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGL_RS02795	COG0163	prenyltransferase activity
SGL_RS02805	COG0589	response to stress
SGL_RS02815	COG5001	Diguanylate cyclase
SGL_RS02815	COG1716	ATPase activity
SGL_RS02825	COG1217	gtp-binding protein TYPA
SGL_RS02840	COG1234	tRNA 3'-trailer cleavage
SGL_RS02850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SGL_RS02865	COG0631	protein serine/threonine phosphatase activity
SGL_RS02870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SGL_RS02880	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
SGL_RS02885	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS02890	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS02895	COG0493	'glutamate synthase
SGL_RS02940	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SGL_RS02940	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SGL_RS02955	COG1982	Orn Lys Arg decarboxylase major
SGL_RS02960	COG0686	Belongs to the AlaDH PNT family
SGL_RS02965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SGL_RS02985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGL_RS02995	COG0673	inositol 2-dehydrogenase activity
SGL_RS03000	COG0700	Nucleoside recognition
SGL_RS03005	COG2715	membrane protein required for spore maturation
SGL_RS03010	COG1640	4-alpha-glucanotransferase
SGL_RS03020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SGL_RS03035	COG2203	Gaf domain
SGL_RS03035	COG4251	negative regulation of phosphorylation
SGL_RS03035	COG5001	Diguanylate cyclase
SGL_RS03035	COG3706	GGDEF domain
SGL_RS03040	COG2205	protein histidine kinase activity
SGL_RS03040	COG0784	Response regulator, receiver
SGL_RS03055	COG1981	membrane
SGL_RS03060	COG0175	sulfate reduction
SGL_RS03065	COG1420	regulation of RNA biosynthetic process
SGL_RS03075	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGL_RS03080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SGL_RS03090	COG0003	Pfam Anion-transporting ATPase
SGL_RS03095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SGL_RS03110	COG0484	heat shock protein binding
SGL_RS03115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGL_RS03125	COG0463	Glycosyl transferase, family 2
SGL_RS03125	COG1216	Glycosyl transferase, family 2
SGL_RS03135	COG1605	Chorismate mutase
SGL_RS03135	COG0077	Prephenate dehydratase
SGL_RS03145	COG2203	Gaf domain
SGL_RS03145	COG4251	negative regulation of phosphorylation
SGL_RS03145	COG5001	Diguanylate cyclase
SGL_RS03145	COG3706	GGDEF domain
SGL_RS03160	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGL_RS03190	COG0589	response to stress
SGL_RS03195	COG2226	methyltransferase
SGL_RS03210	COG0538	isocitrate dehydrogenase activity
SGL_RS03215	COG4636	protein conserved in cyanobacteria
SGL_RS03225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS03240	COG0762	integral membrane protein
SGL_RS03245	COG1840	ABC-type Fe3 transport system, periplasmic component
SGL_RS03250	COG0336	Belongs to the RNA methyltransferase TrmD family
SGL_RS03255	COG0205	6-phosphofructokinase activity
SGL_RS03260	COG1289	transmembrane transporter activity
SGL_RS03265	COG1555	photosystem II stabilization
SGL_RS03275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SGL_RS03280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGL_RS03285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGL_RS03310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SGL_RS03315	COG0277	FAD linked oxidase domain protein
SGL_RS03335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SGL_RS03345	COG0408	coproporphyrinogen oxidase activity
SGL_RS03350	COG5398	heme oxygenase
SGL_RS03360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SGL_RS03380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SGL_RS03385	COG0672	)-iron permease
SGL_RS03390	COG0592	DNA-directed DNA polymerase activity
SGL_RS03395	COG0159	tryptophan synthase activity
SGL_RS03410	COG0436	Aminotransferase
SGL_RS03420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SGL_RS03435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SGL_RS03445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SGL_RS03450	COG0701	Predicted permease
SGL_RS03470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGL_RS03475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGL_RS03480	COG4636	protein conserved in cyanobacteria
SGL_RS03485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGL_RS03505	COG0489	protein tyrosine kinase activity
SGL_RS03505	COG3206	protein involved in exopolysaccharide biosynthesis
SGL_RS03545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGL_RS03585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SGL_RS03590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGL_RS03595	COG1088	dTDP-glucose 4,6-dehydratase activity
SGL_RS03600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGL_RS03620	COG1215	transferase activity, transferring glycosyl groups
SGL_RS03630	COG1215	transferase activity, transferring glycosyl groups
SGL_RS03635	COG0438	transferase activity, transferring glycosyl groups
SGL_RS03660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGL_RS03685	COG0297	glycogen (starch) synthase activity
SGL_RS03690	COG0438	transferase activity, transferring glycosyl groups
SGL_RS03695	COG1598	PFAM Uncharacterised protein family UPF0150
SGL_RS03705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGL_RS03740	COG0110	maltose O-acetyltransferase activity
SGL_RS03755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGL_RS03765	COG3781	membrane
SGL_RS03770	COG0045	succinate-CoA ligase (ADP-forming) activity
SGL_RS03775	COG0861	Integral membrane protein TerC family
SGL_RS03780	COG2268	Band 7 protein
SGL_RS03785	COG0463	Glycosyl transferase, family 2
SGL_RS03790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SGL_RS03800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGL_RS03805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGL_RS03810	COG0004	ammonium transporteR
SGL_RS03815	COG0745	RESPONSE REGULATOR receiver
SGL_RS03830	COG0737	Belongs to the 5'-nucleotidase family
SGL_RS03840	COG0529	Catalyzes the synthesis of activated sulfate
SGL_RS03845	COG0811	peptide transport
SGL_RS03850	COG0848	biopolymer transport protein
SGL_RS03855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGL_RS03855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGL_RS03865	COG0530	calcium, potassium:sodium antiporter activity
SGL_RS03870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGL_RS03885	COG0745	RESPONSE REGULATOR receiver
SGL_RS03890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGL_RS03895	COG1234	tRNA 3'-trailer cleavage
SGL_RS03920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGL_RS03925	COG5001	Diguanylate cyclase
SGL_RS03925	COG3706	GGDEF domain
SGL_RS03925	COG4251	negative regulation of phosphorylation
SGL_RS03925	COG2203	Gaf domain
SGL_RS03935	COG0471	metal ion transport
SGL_RS03935	COG3273	potassium ion transport
SGL_RS03965	COG3854	ATPases associated with a variety of cellular activities
SGL_RS03970	COG0352	thiamine-phosphate diphosphorylase activity
SGL_RS03975	COG0434	BtpA family
SGL_RS04000	COG0564	pseudouridine synthase activity
SGL_RS04005	COG5001	Diguanylate cyclase
SGL_RS04005	COG4251	negative regulation of phosphorylation
SGL_RS04005	COG3706	GGDEF domain
SGL_RS04005	COG2203	Gaf domain
SGL_RS04015	COG0475	glutathione-regulated potassium exporter activity
SGL_RS04050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SGL_RS04055	COG1733	regulation of RNA biosynthetic process
SGL_RS04060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SGL_RS04100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SGL_RS04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGL_RS04125	COG1487	ribonuclease activity
SGL_RS04145	COG2361	Protein of unknown function DUF86
SGL_RS04160	COG0070	glutamate synthase
SGL_RS04160	COG0069	glutamate synthase activity
SGL_RS04160	COG0067	glutamate synthase
SGL_RS04175	COG2133	pyrroloquinoline quinone binding
SGL_RS04180	COG1797	cobyrinic acid a,c-diamide synthase activity
SGL_RS04185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGL_RS04190	COG1022	Amp-dependent synthetase and ligase
SGL_RS04195	COG0784	Response regulator, receiver
SGL_RS04210	COG2203	Gaf domain
SGL_RS04210	COG0840	transmembrane signaling receptor activity
SGL_RS04215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SGL_RS04220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGL_RS04225	COG5001	Diguanylate cyclase
SGL_RS04225	COG4251	negative regulation of phosphorylation
SGL_RS04225	COG3706	GGDEF domain
SGL_RS04225	COG2203	Gaf domain
SGL_RS04230	COG0419	ATPase involved in DNA repair
SGL_RS04235	COG0484	heat shock protein binding
SGL_RS04240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SGL_RS04250	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SGL_RS04275	COG1429	ligase activity, forming nitrogen-metal bonds
SGL_RS04290	COG3956	TIGRFAM MazG family protein
SGL_RS04300	COG5002	protein histidine kinase activity
SGL_RS04315	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGL_RS04330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SGL_RS04335	COG1247	-acetyltransferase
SGL_RS04340	COG0174	glutamine synthetase
SGL_RS04350	COG5001	Diguanylate cyclase
SGL_RS04350	COG4251	negative regulation of phosphorylation
SGL_RS04350	COG2203	Gaf domain
SGL_RS04350	COG3706	GGDEF domain
SGL_RS04360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGL_RS04365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGL_RS04380	COG2310	stress, protein
SGL_RS04385	COG0076	glutamate decarboxylase activity
SGL_RS04400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGL_RS04405	COG0829	nickel cation binding
SGL_RS04420	COG1045	serine acetyltransferase
SGL_RS04435	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SGL_RS04450	COG0271	Belongs to the BolA IbaG family
SGL_RS04455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SGL_RS04460	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SGL_RS04465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGL_RS04470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SGL_RS04480	COG0804	urea catabolic process
SGL_RS04495	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS04515	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGL_RS04520	COG1773	rubredoxin
SGL_RS04525	COG4447	cellulose binding
SGL_RS04550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGL_RS04560	COG3385	transposase activity
SGL_RS04580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGL_RS04585	COG0784	Response regulator, receiver
SGL_RS04590	COG3228	Belongs to the MtfA family
SGL_RS04625	COG1121	(ABC) transporter
SGL_RS04630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGL_RS04645	COG1702	phosphate starvation-inducible protein PhoH
SGL_RS04660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGL_RS04680	COG0484	heat shock protein binding
SGL_RS04685	COG0443	Heat shock 70 kDa protein
SGL_RS04690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGL_RS04720	COG3659	wide pore channel activity
SGL_RS04730	COG2247	cell wall binding repeat
SGL_RS04730	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGL_RS04790	COG0768	penicillin binding
SGL_RS04800	COG0247	lactate metabolic process
SGL_RS04810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGL_RS04820	COG0583	DNA-binding transcription factor activity
SGL_RS04830	COG0384	phenazine biosynthesis protein PhzF
SGL_RS04840	COG2319	Wd-40 repeat
SGL_RS04845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGL_RS04870	COG0475	glutathione-regulated potassium exporter activity
SGL_RS04870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SGL_RS04875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGL_RS04895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SGL_RS04900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SGL_RS04915	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SGL_RS04920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SGL_RS04935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SGL_RS04940	COG0629	single-stranded DNA binding
SGL_RS04955	COG0668	transmembrane transport
SGL_RS04965	COG0745	RESPONSE REGULATOR receiver
SGL_RS04970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGL_RS04970	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SGL_RS04975	COG3937	granule-associated protein
SGL_RS04990	COG2226	methyltransferase
SGL_RS05000	COG0681	Belongs to the peptidase S26 family
SGL_RS05010	COG1271	oxidase subunit
SGL_RS05015	COG1294	oxidase, subunit
SGL_RS05020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SGL_RS05025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SGL_RS05030	COG0412	Dienelactone hydrolase
SGL_RS05075	COG0643	Histidine kinase
SGL_RS05075	COG0784	Response regulator, receiver
SGL_RS05075	COG2198	Histidine kinase
SGL_RS05080	COG2203	Gaf domain
SGL_RS05080	COG0840	transmembrane signaling receptor activity
SGL_RS05095	COG0784	Response regulator, receiver
SGL_RS05100	COG0557	exoribonuclease II activity
SGL_RS05110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGL_RS05125	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGL_RS05135	COG5002	protein histidine kinase activity
SGL_RS05140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SGL_RS05150	COG1309	transcriptional regulator
SGL_RS05175	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGL_RS05185	COG2385	sporulation resulting in formation of a cellular spore
SGL_RS05195	COG3411	Ferredoxin
SGL_RS05200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGL_RS05225	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SGL_RS05230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SGL_RS05235	COG0237	dephospho-CoA kinase activity
SGL_RS05240	COG0237	dephospho-CoA kinase activity
SGL_RS05270	COG0515	serine threonine protein kinase
SGL_RS05275	COG0515	serine threonine protein kinase
SGL_RS05285	COG2988	succinylglutamate desuccinylase activity
SGL_RS05290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGL_RS05300	COG0739	heme binding
SGL_RS05305	COG0587	DNA-directed DNA polymerase activity
SGL_RS05320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SGL_RS05350	COG1006	Multisubunit Na H antiporter MnhC subunit
SGL_RS05355	COG0651	ATP synthesis coupled electron transport
SGL_RS05360	COG1006	Multisubunit Na H antiporter MnhC subunit
SGL_RS05425	COG1132	(ABC) transporter
SGL_RS05430	COG3063	Type IV pilus biogenesis stability protein PilW
SGL_RS05435	COG2217	Heavy metal translocating P-type atpase
SGL_RS05440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGL_RS05445	COG0745	RESPONSE REGULATOR receiver
SGL_RS05455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGL_RS05460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGL_RS05470	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SGL_RS05500	COG0557	exoribonuclease II activity
SGL_RS05510	COG2208	phosphoserine phosphatase activity
SGL_RS05520	COG0165	Argininosuccinate lyase
SGL_RS05525	COG2816	NAD+ diphosphatase activity
SGL_RS05540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SGL_RS05545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGL_RS05550	COG1845	cytochrome c oxidase, subunit III
SGL_RS05555	COG3118	belongs to the thioredoxin family
SGL_RS05565	COG1116	anion transmembrane transporter activity
SGL_RS05570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGL_RS05585	COG0375	protein maturation
SGL_RS05590	COG0010	Belongs to the arginase family
SGL_RS05605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGL_RS05615	COG0495	leucyl-tRNA aminoacylation
SGL_RS05620	COG0786	glutamate:sodium symporter activity
SGL_RS05630	COG2205	protein histidine kinase activity
SGL_RS05640	COG1132	(ABC) transporter
SGL_RS05660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SGL_RS05665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGL_RS05670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGL_RS05695	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SGL_RS05700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGL_RS05710	COG0254	rRNA binding
SGL_RS05715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SGL_RS05720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SGL_RS05725	COG0101	tRNA pseudouridine synthase activity
SGL_RS05730	COG0203	ribosomal protein L17
SGL_RS05735	COG0202	RNA polymerase activity
SGL_RS05740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SGL_RS05745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SGL_RS05750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SGL_RS05755	COG0563	adenylate kinase activity
SGL_RS05760	COG0201	protein transport
SGL_RS05765	COG0200	Binds to the 23S rRNA
SGL_RS05770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SGL_RS05775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SGL_RS05780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SGL_RS05785	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SGL_RS05790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SGL_RS05795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGL_RS05800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SGL_RS05805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SGL_RS05810	COG0255	Belongs to the universal ribosomal protein uL29 family
SGL_RS05815	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SGL_RS05820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SGL_RS05825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SGL_RS05830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SGL_RS05835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SGL_RS05840	COG0089	rRNA binding
SGL_RS05845	COG0088	Forms part of the polypeptide exit tunnel
SGL_RS05850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SGL_RS05855	COG0783	Belongs to the Dps family
SGL_RS05875	COG2010	Cytochrome c
SGL_RS05885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGL_RS05890	COG0830	nickel cation binding
SGL_RS05900	COG1131	(ABC) transporter
SGL_RS05925	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGL_RS05930	COG0085	RNA polymerase activity
SGL_RS05935	COG0084	hydrolase, TatD family'
SGL_RS05940	COG0268	Binds directly to 16S ribosomal RNA
SGL_RS05945	COG5002	protein histidine kinase activity
SGL_RS05955	COG0210	DNA helicase
SGL_RS05955	COG0210	DNA helicase
SGL_RS05960	COG1196	nuclear chromosome segregation
SGL_RS05965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SGL_RS05985	COG0758	DNA mediated transformation
SGL_RS05985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SGL_RS05990	COG0393	Putative heavy-metal-binding
SGL_RS06000	COG0450	alkyl hydroperoxide reductase
SGL_RS06005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SGL_RS06020	COG1175	transmembrane transport
SGL_RS06030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGL_RS06055	COG3347	Dehydrogenase
SGL_RS06055	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS06075	COG5001	Diguanylate cyclase
SGL_RS06075	COG3706	GGDEF domain
SGL_RS06075	COG2203	Gaf domain
SGL_RS06075	COG4251	negative regulation of phosphorylation
SGL_RS06080	COG0745	RESPONSE REGULATOR receiver
SGL_RS06085	COG0784	Response regulator, receiver
SGL_RS06095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SGL_RS06105	COG2239	Acts as a magnesium transporter
SGL_RS06135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGL_RS06140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SGL_RS06145	COG1799	cell septum assembly
SGL_RS06150	COG0662	Cupin 2, conserved barrel domain protein
SGL_RS06150	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SGL_RS06165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SGL_RS06170	COG0459	protein refolding
SGL_RS06190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGL_RS06195	COG0222	ribosome binding
SGL_RS06200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SGL_RS06205	COG0081	regulation of translation
SGL_RS06210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SGL_RS06215	COG0250	Participates in transcription elongation, termination and antitermination
SGL_RS06220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SGL_RS06230	COG0335	large ribosomal subunit rRNA binding
SGL_RS06260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGL_RS06270	COG3243	poly(R)-hydroxyalkanoic acid synthase
SGL_RS06280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SGL_RS06290	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS06295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGL_RS06305	COG2885	chlorophyll binding
SGL_RS06310	COG2885	chlorophyll binding
SGL_RS06320	COG1132	(ABC) transporter
SGL_RS06330	COG0438	transferase activity, transferring glycosyl groups
SGL_RS06340	COG0745	RESPONSE REGULATOR receiver
SGL_RS06345	COG0022	dehydrogenase e1 component
SGL_RS06345	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGL_RS06350	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS06355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS06360	COG1929	Belongs to the glycerate kinase type-1 family
SGL_RS06365	COG3659	wide pore channel activity
SGL_RS06370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGL_RS06375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SGL_RS06380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGL_RS06410	COG0776	regulation of translation
SGL_RS06425	COG0514	ATP-dependent DNA helicase (RecQ)
SGL_RS06435	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SGL_RS06440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGL_RS06450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SGL_RS06500	COG0438	transferase activity, transferring glycosyl groups
SGL_RS06505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGL_RS06510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SGL_RS06515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGL_RS06530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SGL_RS06535	COG0242	peptide deformylase activity
SGL_RS06545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SGL_RS06575	COG0243	molybdopterin cofactor binding
SGL_RS06580	COG1116	anion transmembrane transporter activity
SGL_RS06585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGL_RS06585	COG1116	anion transmembrane transporter activity
SGL_RS06590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGL_RS06595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGL_RS06600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGL_RS06610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SGL_RS06615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SGL_RS06625	COG0793	Belongs to the peptidase S41A family
SGL_RS06635	COG0275	rRNA processing
SGL_RS06645	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SGL_RS06670	COG1090	epimerase
SGL_RS06675	COG3842	ATPase activity
SGL_RS06680	COG0515	serine threonine protein kinase
SGL_RS06690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGL_RS06695	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SGL_RS06700	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SGL_RS06705	COG0659	secondary active sulfate transmembrane transporter activity
SGL_RS06710	COG0589	response to stress
SGL_RS06715	COG1233	COG1233 Phytoene dehydrogenase and related
SGL_RS06730	COG1053	succinate dehydrogenase
SGL_RS06735	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGL_RS06740	COG0537	adenosine 5'-monophosphoramidase activity
SGL_RS06770	COG0402	S-adenosylhomocysteine deaminase activity
SGL_RS06785	COG2267	carboxylic ester hydrolase activity
SGL_RS06795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SGL_RS06800	COG0189	ligase activity
SGL_RS06810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SGL_RS06815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SGL_RS06840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SGL_RS06845	COG0312	modulator of DNA gyrase
SGL_RS06865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SGL_RS06875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGL_RS06875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGL_RS06890	COG2140	Oxalate decarboxylase
SGL_RS06895	COG0058	SHG alpha-glucan phosphorylase activity
SGL_RS06920	COG0515	serine threonine protein kinase
SGL_RS06940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SGL_RS06940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SGL_RS06945	COG3850	Histidine kinase
SGL_RS06945	COG4999	Histidine kinase
SGL_RS06945	COG2205	protein histidine kinase activity
SGL_RS06945	COG3437	response regulator, receiver
SGL_RS06975	COG0546	phosphoglycolate phosphatase activity
SGL_RS06980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SGL_RS06985	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SGL_RS07010	COG0539	negative regulation of cytoplasmic translation
SGL_RS07025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGL_RS07030	COG1132	(ABC) transporter
SGL_RS07035	COG0469	pyruvate kinase activity
SGL_RS07055	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGL_RS07060	COG1268	BioY protein
SGL_RS07065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SGL_RS07085	COG3659	wide pore channel activity
SGL_RS07090	COG0765	amino acid transport
SGL_RS07100	COG0058	SHG alpha-glucan phosphorylase activity
SGL_RS07110	COG0575	Belongs to the CDS family
SGL_RS07135	COG1970	mechanosensitive ion channel activity
SGL_RS07140	COG0632	four-way junction helicase activity
SGL_RS07145	COG1836	PFAM Integral membrane protein DUF92
SGL_RS07150	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGL_RS07155	COG0724	RNA recognition motif
SGL_RS07160	COG0154	amidase activity
SGL_RS07165	COG0739	heme binding
SGL_RS07170	COG0509	glycine decarboxylation via glycine cleavage system
SGL_RS07200	COG1316	TRANSCRIPTIONal
SGL_RS07215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SGL_RS07230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SGL_RS07235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SGL_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS07265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGL_RS07280	COG0322	excinuclease ABC activity
SGL_RS07305	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SGL_RS07315	COG3258	Cytochrome c
SGL_RS07320	COG0723	plastoquinol--plastocyanin reductase activity
SGL_RS07340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SGL_RS07365	COG2319	Wd-40 repeat
SGL_RS07370	COG2319	Wd-40 repeat
SGL_RS07390	COG1082	Xylose isomerase domain protein TIM barrel
SGL_RS07405	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SGL_RS07430	COG1366	Belongs to the anti-sigma-factor antagonist family
SGL_RS07445	COG2208	phosphoserine phosphatase activity
SGL_RS07445	COG2770	Histidine kinase
SGL_RS07460	COG3385	transposase activity
SGL_RS07485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGL_RS07490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGL_RS07530	COG1741	Belongs to the pirin family
SGL_RS07540	COG1193	negative regulation of DNA recombination
SGL_RS07545	COG0631	protein serine/threonine phosphatase activity
SGL_RS07550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGL_RS07560	COG3937	granule-associated protein
SGL_RS07575	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGL_RS07580	COG3932	Exopolysaccharide synthesis, ExoD
SGL_RS07585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SGL_RS07595	COG0360	Binds together with S18 to 16S ribosomal RNA
SGL_RS07600	COG0179	Fumarylacetoacetate (FAA) hydrolase
SGL_RS07605	COG1413	lyase activity
SGL_RS07610	COG0641	radical SAM
SGL_RS07645	COG0083	homoserine kinase activity
SGL_RS07655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGL_RS07660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS07670	COG0196	riboflavin kinase activity
SGL_RS07690	COG0180	Tryptophanyl-tRNA synthetase
SGL_RS07695	COG1713	HD superfamily hydrolase involved in NAD metabolism
SGL_RS07700	COG0799	negative regulation of ribosome biogenesis
SGL_RS07710	COG0181	hydroxymethylbilane synthase activity
SGL_RS07715	COG0427	acetyl-CoA hydrolase
SGL_RS07720	COG0857	belongs to the CobB CobQ family
SGL_RS07720	COG0280	phosphate acetyltransferase
SGL_RS07730	COG1489	DNA binding
SGL_RS07740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGL_RS07750	COG0602	queuosine metabolic process
SGL_RS07755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SGL_RS07760	COG0612	Peptidase, M16
SGL_RS07765	COG0612	Peptidase, M16
SGL_RS07775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SGL_RS07790	COG0187	DNA topoisomerase II activity
SGL_RS07790	COG1372	Participates in initiation and elongation during chromosome replication
SGL_RS07805	COG0646	methionine synthase
SGL_RS07805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SGL_RS07815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGL_RS07840	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS07850	COG2197	response regulator
SGL_RS07855	COG5001	Diguanylate cyclase
SGL_RS07855	COG4251	negative regulation of phosphorylation
SGL_RS07855	COG2203	Gaf domain
SGL_RS07855	COG3706	GGDEF domain
SGL_RS07865	COG0616	signal peptide processing
SGL_RS07875	COG0596	Alpha beta hydrolase
SGL_RS07880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SGL_RS07890	COG0747	negative chemotaxis
SGL_RS07900	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
SGL_RS07940	COG4968	Prepilin-type N-terminal cleavage methylation domain
SGL_RS07945	COG4968	Prepilin-type N-terminal cleavage methylation domain
SGL_RS07970	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS07975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGL_RS07980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGL_RS07990	COG2199	diguanylate cyclase activity
SGL_RS07995	COG0750	zinc metalloprotease
SGL_RS08000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SGL_RS08010	COG0590	tRNA wobble adenosine to inosine editing
SGL_RS08020	COG0415	Belongs to the DNA photolyase family
SGL_RS08030	COG3409	Peptidoglycan-binding domain 1 protein
SGL_RS08030	COG3429	Glucose-6-phosphate dehydrogenase subunit
SGL_RS08040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SGL_RS08045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SGL_RS08060	COG1122	ATPase activity
SGL_RS08065	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SGL_RS08075	COG0678	peroxiredoxin activity
SGL_RS08115	COG1252	NADH dehydrogenase
SGL_RS08125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGL_RS08150	COG0415	Belongs to the DNA photolyase family
SGL_RS08165	COG1595	DNA-templated transcription, initiation
SGL_RS08210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SGL_RS08220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SGL_RS08225	COG3339	Conserved Protein
SGL_RS08235	COG0312	modulator of DNA gyrase
SGL_RS08240	COG0482	sulfurtransferase activity
SGL_RS08255	COG0488	(ABC) transporter
SGL_RS08260	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SGL_RS08270	COG0284	orotidine-5'-phosphate decarboxylase activity
SGL_RS08315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SGL_RS08325	COG0697	spore germination
SGL_RS08360	COG0583	DNA-binding transcription factor activity
SGL_RS08385	COG2814	Major facilitator Superfamily
SGL_RS08390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGL_RS08395	COG0573	inorganic phosphate transmembrane transporter activity
SGL_RS08400	COG0581	inorganic phosphate transmembrane transporter activity
SGL_RS08405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGL_RS08410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGL_RS08415	COG2154	pterin-4-alpha-carbinolamine dehydratase
SGL_RS08440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGL_RS08440	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGL_RS08445	COG1562	ergosterol biosynthetic process
SGL_RS08450	COG3788	relative of glutathione S-transferase, MAPEG superfamily
SGL_RS08455	COG0831	urea catabolic process
SGL_RS08465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SGL_RS08485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGL_RS08490	COG0730	response to heat
SGL_RS08500	COG2188	Transcriptional regulator
SGL_RS08515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGL_RS08520	COG0640	Transcriptional regulator
SGL_RS08525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SGL_RS08530	COG1754	DNA topoisomerase type I activity
SGL_RS08530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGL_RS08565	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SGL_RS08595	COG2264	protein methyltransferase activity
SGL_RS08600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGL_RS08615	COG0386	Belongs to the glutathione peroxidase family
SGL_RS08620	COG0183	Belongs to the thiolase family
SGL_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS08635	COG4999	Histidine kinase
SGL_RS08635	COG3437	response regulator, receiver
SGL_RS08635	COG3850	Histidine kinase
SGL_RS08635	COG2205	protein histidine kinase activity
SGL_RS08655	COG4242	Belongs to the peptidase S51 family
SGL_RS08660	COG0189	ligase activity
SGL_RS08660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGL_RS08695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SGL_RS08700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGL_RS08710	COG0285	dihydrofolate synthase activity
SGL_RS08730	COG4636	protein conserved in cyanobacteria
SGL_RS08745	COG1606	tRNA processing
SGL_RS08755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SGL_RS08765	COG2045	Belongs to the ComB family
SGL_RS08770	COG0778	Nitroreductase
SGL_RS08775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SGL_RS08785	COG0516	GMP reductase activity
SGL_RS08790	COG0395	ABC-type sugar transport system, permease component
SGL_RS08795	COG3268	Saccharopine dehydrogenase
SGL_RS08810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGL_RS08815	COG1121	(ABC) transporter
SGL_RS08820	COG0803	Belongs to the bacterial solute-binding protein 9 family
SGL_RS08830	COG4251	negative regulation of phosphorylation
SGL_RS08835	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SGL_RS08845	COG0583	DNA-binding transcription factor activity
SGL_RS08850	COG0025	NhaP-type Na H and K H
SGL_RS08855	COG2197	response regulator
SGL_RS08860	COG5002	protein histidine kinase activity
SGL_RS08865	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SGL_RS08870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SGL_RS08880	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SGL_RS08885	COG2205	protein histidine kinase activity
SGL_RS08895	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGL_RS08915	COG2385	sporulation resulting in formation of a cellular spore
SGL_RS08920	COG0649	NAD binding
SGL_RS08935	COG0429	hydrolase of the alpha beta-hydrolase fold
SGL_RS08945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGL_RS08950	COG3536	Protein conserved in bacteria
SGL_RS08955	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SGL_RS08960	COG0716	FMN binding
SGL_RS08970	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGL_RS08975	COG0012	GTP binding
SGL_RS08980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGL_RS09035	COG3842	ATPase activity
SGL_RS09045	COG1840	ABC-type Fe3 transport system, periplasmic component
SGL_RS09050	COG0222	ribosome binding
SGL_RS09060	COG2066	Belongs to the glutaminase family
SGL_RS09075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SGL_RS09090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SGL_RS09095	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SGL_RS09100	COG1333	cytochrome c biogenesis protein
SGL_RS09110	COG1657	PFAM Prenyltransferase squalene oxidase
SGL_RS09160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SGL_RS09170	COG1494	fructose-1,6-bisphosphatase
SGL_RS09185	COG2346	COG2346, Truncated hemoglobins
SGL_RS09190	COG3850	Histidine kinase
SGL_RS09190	COG4999	Histidine kinase
SGL_RS09190	COG3437	response regulator, receiver
SGL_RS09190	COG2205	protein histidine kinase activity
SGL_RS09200	COG3437	response regulator, receiver
SGL_RS09205	COG1917	Cupin 2, conserved barrel domain protein
SGL_RS09210	COG0552	protein localization to endoplasmic reticulum
SGL_RS09220	COG2205	protein histidine kinase activity
SGL_RS09220	COG5002	protein histidine kinase activity
SGL_RS09220	COG0784	Response regulator, receiver
SGL_RS09225	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SGL_RS09235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGL_RS09255	COG0667	Aldo Keto reductase
SGL_RS09260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGL_RS09270	COG0442	prolyl-tRNA aminoacylation
SGL_RS09280	COG4372	Transposase
SGL_RS09285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGL_RS09310	COG0438	transferase activity, transferring glycosyl groups
SGL_RS09315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGL_RS09320	COG0416	fatty acid biosynthetic process
SGL_RS09325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGL_RS09340	COG0347	Belongs to the P(II) protein family
SGL_RS09345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGL_RS09370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SGL_RS09375	COG0473	3-isopropylmalate dehydrogenase activity
SGL_RS09385	COG1575	Belongs to the MenA family. Type 1 subfamily
SGL_RS09395	COG0656	L-ascorbic acid biosynthetic process
SGL_RS09400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGL_RS09430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SGL_RS09445	COG2161	toxin-antitoxin pair type II binding
SGL_RS09450	COG4115	mRNA cleavage
SGL_RS09465	COG3385	transposase activity
SGL_RS09480	COG3385	transposase activity
SGL_RS09490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SGL_RS09490	COG0517	IMP dehydrogenase activity
SGL_RS09505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SGL_RS09515	COG1215	transferase activity, transferring glycosyl groups
SGL_RS09540	COG1216	Glycosyl transferase, family 2
SGL_RS09545	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SGL_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS09585	COG0463	Glycosyl transferase, family 2
SGL_RS09590	COG0113	porphobilinogen synthase activity
SGL_RS09600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGL_RS09605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SGL_RS09635	COG0312	modulator of DNA gyrase
SGL_RS09640	COG2890	protein-(glutamine-N5) methyltransferase activity
SGL_RS09645	COG2205	protein histidine kinase activity
SGL_RS09660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGL_RS09665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SGL_RS09690	COG0438	transferase activity, transferring glycosyl groups
SGL_RS09700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGL_RS09700	COG2205	protein histidine kinase activity
SGL_RS09705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SGL_RS09710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SGL_RS09715	COG0612	Peptidase, M16
SGL_RS09720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGL_RS09725	COG3259	Nickel-dependent hydrogenase
SGL_RS09740	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
SGL_RS09745	COG1034	ATP synthesis coupled electron transport
SGL_RS09780	COG0702	epimerase
SGL_RS09815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGL_RS09820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGL_RS09835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SGL_RS09845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SGL_RS09850	COG0673	inositol 2-dehydrogenase activity
SGL_RS09865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SGL_RS09870	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SGL_RS09905	COG0095	Lipoate-protein ligase
SGL_RS09925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SGL_RS09935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGL_RS09945	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SGL_RS09950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGL_RS09955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGL_RS09960	COG0457	Tetratricopeptide repeat
SGL_RS09965	COG1160	GTP binding
SGL_RS09985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SGL_RS10000	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SGL_RS10005	COG0052	Belongs to the universal ribosomal protein uS2 family
SGL_RS10015	COG0387	Pfam Sodium calcium exchanger
SGL_RS10020	COG0717	Belongs to the dCTP deaminase family
SGL_RS10055	COG3385	transposase activity
SGL_RS10060	COG1253	flavin adenine dinucleotide binding
SGL_RS10070	COG3046	protein related to deoxyribodipyrimidine photolyase
SGL_RS10075	COG0517	IMP dehydrogenase activity
SGL_RS10075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGL_RS10075	COG0617	tRNA 3'-terminal CCA addition
SGL_RS10085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SGL_RS10105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SGL_RS10105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SGL_RS10110	COG0288	reversible hydration of carbon dioxide
SGL_RS10115	COG1045	serine acetyltransferase
SGL_RS10125	COG0166	Belongs to the GPI family
SGL_RS10130	COG3239	Fatty acid desaturase
SGL_RS10135	COG1672	PFAM Archaeal ATPase
SGL_RS10140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGL_RS10145	COG2010	Cytochrome c
SGL_RS10150	COG0359	binds to the 23S rRNA
SGL_RS10160	COG1032	radical SAM domain protein
SGL_RS10190	COG0298	carbon dioxide binding
SGL_RS10195	COG0109	protoheme IX farnesyltransferase activity
SGL_RS10200	COG1612	heme a metabolic process
SGL_RS10220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SGL_RS10225	COG5001	Diguanylate cyclase
SGL_RS10225	COG1716	ATPase activity
SGL_RS10230	COG3631	Ketosteroid isomerase-related protein
SGL_RS10240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGL_RS10240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGL_RS10250	COG0107	imidazoleglycerol-phosphate synthase activity
SGL_RS10275	COG2202	Pas domain
SGL_RS10275	COG2205	protein histidine kinase activity
SGL_RS10295	COG4999	Histidine kinase
SGL_RS10295	COG3850	Histidine kinase
SGL_RS10295	COG3437	response regulator, receiver
SGL_RS10295	COG2205	protein histidine kinase activity
SGL_RS10305	COG4956	integral membrane protein (PIN domain superfamily)
SGL_RS10320	COG1160	GTP binding
SGL_RS10330	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGL_RS10345	COG0432	Pfam Uncharacterised protein family UPF0047
SGL_RS10350	COG2197	response regulator
SGL_RS10355	COG3842	ATPase activity
SGL_RS10365	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGL_RS10370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SGL_RS10380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGL_RS10385	COG5398	heme oxygenase
SGL_RS10390	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SGL_RS10400	COG1316	TRANSCRIPTIONal
SGL_RS10415	COG2770	Histidine kinase
SGL_RS10415	COG2208	phosphoserine phosphatase activity
SGL_RS10420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGL_RS10430	COG0539	negative regulation of cytoplasmic translation
SGL_RS10435	COG0358	DNA primase activity
SGL_RS10445	COG0009	L-threonylcarbamoyladenylate synthase
SGL_RS10465	COG0589	response to stress
SGL_RS10490	COG2082	Precorrin-8x methylmutase
SGL_RS10500	COG0594	ribonuclease P activity
SGL_RS10510	COG0706	membrane insertase activity
SGL_RS10520	COG0484	heat shock protein binding
SGL_RS10525	COG0483	inositol monophosphate 1-phosphatase activity
SGL_RS10530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGL_RS10540	COG0791	NLP P60 protein
SGL_RS10555	COG0540	Belongs to the ATCase OTCase family
SGL_RS10570	COG1215	transferase activity, transferring glycosyl groups
SGL_RS10580	COG3000	fatty acid hydroxylase
SGL_RS10580	COG0300	oxidoreductase activity
SGL_RS10585	COG2211	Major facilitator Superfamily
SGL_RS10605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGL_RS10620	COG0723	plastoquinol--plastocyanin reductase activity
SGL_RS10625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SGL_RS10630	COG2274	protein secretion by the type I secretion system
SGL_RS10640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGL_RS10645	COG2192	nodulation
SGL_RS10655	COG0772	Belongs to the SEDS family
SGL_RS10660	COG0405	Gamma-glutamyltransferase
SGL_RS10675	COG3659	wide pore channel activity
SGL_RS10715	COG0037	tRNA processing
SGL_RS10720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGL_RS10725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS10730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS10735	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS10775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGL_RS10785	COG0628	permease
SGL_RS10800	COG0066	3-isopropylmalate dehydratase activity
SGL_RS10805	COG0504	CTP synthase activity
SGL_RS10820	COG2204	response regulator
SGL_RS10830	COG0259	pyridoxamine-phosphate oxidase activity
SGL_RS10850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SGL_RS10865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGL_RS10870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGL_RS10875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SGL_RS10875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SGL_RS10880	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SGL_RS10890	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGL_RS10895	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS10910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SGL_RS10920	COG0051	transcription antitermination factor activity, RNA binding
SGL_RS10925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SGL_RS10930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGL_RS10935	COG0049	tRNA binding
SGL_RS10940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SGL_RS10950	COG0151	Belongs to the GarS family
SGL_RS10960	COG0698	ribose 5-phosphate isomerase
SGL_RS10995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGL_RS11000	COG2046	Belongs to the sulfate adenylyltransferase family
SGL_RS11005	COG0297	glycogen (starch) synthase activity
SGL_RS11020	COG0644	oxidoreductase
SGL_RS11025	COG0371	Dehydrogenase
SGL_RS11040	COG2119	membrane
SGL_RS11045	COG0386	Belongs to the glutathione peroxidase family
SGL_RS11060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SGL_RS11080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SGL_RS11085	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SGL_RS11095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SGL_RS11100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGL_RS11110	COG0375	protein maturation
SGL_RS11125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SGL_RS11130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SGL_RS11135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SGL_RS11140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGL_RS11145	COG1134	teichoic acid transport
SGL_RS11170	COG1012	belongs to the aldehyde dehydrogenase family
SGL_RS11185	COG3385	transposase activity
SGL_RS11220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGL_RS11230	COG1304	FMN binding
SGL_RS11235	COG0745	RESPONSE REGULATOR receiver
SGL_RS11245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SGL_RS11255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGL_RS11255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGL_RS11260	COG3706	GGDEF domain
SGL_RS11260	COG2203	Gaf domain
SGL_RS11260	COG4251	negative regulation of phosphorylation
SGL_RS11260	COG5001	Diguanylate cyclase
SGL_RS11265	COG0784	Response regulator, receiver
SGL_RS11275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGL_RS11275	COG0072	phenylalanine-tRNA ligase activity
SGL_RS11280	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS11280	COG0515	serine threonine protein kinase
SGL_RS11285	COG2197	response regulator
SGL_RS11290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SGL_RS11305	COG0157	Belongs to the NadC ModD family
SGL_RS11320	COG2082	Precorrin-8x methylmutase
SGL_RS11325	COG0612	Peptidase, M16
SGL_RS11330	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGL_RS11340	COG0656	L-ascorbic acid biosynthetic process
SGL_RS11345	COG3588	fructose-bisphosphate aldolase
SGL_RS11355	COG0798	PFAM Bile acid sodium symporter
SGL_RS11360	COG0431	NADPH-dependent FMN reductase
SGL_RS11365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGL_RS11385	COG0488	(ABC) transporter
SGL_RS11395	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SGL_RS11415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SGL_RS11420	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SGL_RS11425	COG0561	phosphatase activity
SGL_RS11430	COG1366	Belongs to the anti-sigma-factor antagonist family
SGL_RS11435	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SGL_RS11440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGL_RS11450	COG0215	cysteine-tRNA ligase activity
SGL_RS11455	COG0424	maF-like protein
SGL_RS11470	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SGL_RS11475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SGL_RS11480	COG0463	Glycosyl transferase, family 2
SGL_RS11485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SGL_RS11500	COG1472	Belongs to the glycosyl hydrolase 3 family
SGL_RS11505	COG2816	NAD+ diphosphatase activity
SGL_RS11510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SGL_RS11515	COG1280	lysine exporter protein (LysE YggA)
SGL_RS11530	COG0564	pseudouridine synthase activity
SGL_RS11540	COG0438	transferase activity, transferring glycosyl groups
SGL_RS11565	COG3385	transposase activity
SGL_RS11585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SGL_RS11600	COG0438	transferase activity, transferring glycosyl groups
SGL_RS11610	COG0500	methyltransferase
SGL_RS11615	COG0542	response to heat
SGL_RS11625	COG0572	uridine kinase
SGL_RS11630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SGL_RS11635	COG0561	phosphatase activity
SGL_RS11650	COG0571	ribonuclease III activity
SGL_RS11655	COG0390	transport system, permease component
SGL_RS11660	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SGL_RS11665	COG2161	toxin-antitoxin pair type II binding
SGL_RS11680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGL_RS11685	COG0426	domain, Protein
SGL_RS11685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGL_RS11690	COG0497	DNA recombination
SGL_RS11700	COG3751	2OG-Fe(II) oxygenase superfamily
SGL_RS11730	COG2161	toxin-antitoxin pair type II binding
SGL_RS11755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGL_RS11760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGL_RS11775	COG1446	asparaginase
SGL_RS11780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGL_RS11790	COG0832	Belongs to the urease beta subunit family
SGL_RS11800	COG2226	methyltransferase
SGL_RS11815	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SGL_RS11825	COG0025	NhaP-type Na H and K H
SGL_RS11835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SGL_RS11845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SGL_RS11885	COG3239	Fatty acid desaturase
SGL_RS11895	COG1950	PFAM Membrane protein of
SGL_RS11910	COG1253	flavin adenine dinucleotide binding
SGL_RS11915	COG0228	four-way junction DNA binding
SGL_RS11935	COG2010	Cytochrome c
SGL_RS11950	COG0802	atpase or kinase
SGL_RS11955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGL_RS11955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SGL_RS11980	COG0126	phosphoglycerate kinase activity
SGL_RS11985	COG0583	DNA-binding transcription factor activity
SGL_RS11990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGL_RS12025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGL_RS12040	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SGL_RS12045	COG0347	Belongs to the P(II) protein family
SGL_RS12060	COG0135	phosphoribosylanthranilate isomerase activity
SGL_RS12065	COG0697	spore germination
SGL_RS12080	COG0418	dihydroorotase activity
SGL_RS12085	COG2226	methyltransferase
SGL_RS12100	COG1672	PFAM Archaeal ATPase
SGL_RS12100	COG2319	Wd-40 repeat
SGL_RS12145	COG0515	serine threonine protein kinase
SGL_RS12145	COG2815	serine threonine protein kinase
SGL_RS12170	COG0233	cytoplasmic translational termination
SGL_RS12175	COG0528	UMP kinase activity
SGL_RS12180	COG1598	PFAM Uncharacterised protein family UPF0150
SGL_RS12190	COG0542	response to heat
SGL_RS12215	COG1459	type II secretion system
SGL_RS12220	COG1459	type II secretion system
SGL_RS12225	COG0740	serine-type endopeptidase activity
SGL_RS12230	COG0740	serine-type endopeptidase activity
SGL_RS12235	COG0006	proline dipeptidase activity
SGL_RS12240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGL_RS12255	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
SGL_RS12265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SGL_RS12270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGL_RS12305	COG2165	general secretion pathway protein
SGL_RS12310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SGL_RS12345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SGL_RS12365	COG0105	UTP biosynthetic process
SGL_RS12395	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SGL_RS12400	COG2937	Belongs to the GPAT DAPAT family
SGL_RS12410	COG0501	Belongs to the peptidase M48B family
SGL_RS12430	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SGL_RS12440	COG0463	Glycosyl transferase, family 2
SGL_RS12450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SGL_RS12465	COG0508	dehydrogenase complex catalyzes the overall conversion of
SGL_RS12475	COG2217	Heavy metal translocating P-type atpase
SGL_RS12485	COG0217	transcriptional regulatory protein
SGL_RS12490	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SGL_RS12495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SGL_RS12500	COG0739	heme binding
SGL_RS12505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SGL_RS12510	COG0321	lipoyl(octanoyl) transferase activity
SGL_RS12525	COG0297	glycogen (starch) synthase activity
SGL_RS12540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGL_RS12545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SGL_RS12550	COG2198	Histidine kinase
SGL_RS12550	COG0784	Response regulator, receiver
SGL_RS12550	COG2198	Histidine kinase
SGL_RS12550	COG0643	Histidine kinase
SGL_RS12550	COG0784	Response regulator, receiver
SGL_RS12550	COG0643	Histidine kinase
SGL_RS12570	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS12585	COG1178	ABC-type Fe3 transport system permease component
SGL_RS12590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SGL_RS12615	COG2197	response regulator
SGL_RS12620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS12625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS12650	COG0237	dephospho-CoA kinase activity
SGL_RS12650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGL_RS12690	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS12700	COG0516	GMP reductase activity
SGL_RS12700	COG0517	IMP dehydrogenase activity
SGL_RS12710	COG1937	Protein conserved in bacteria
SGL_RS12725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SGL_RS12745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGL_RS12750	COG0443	Heat shock 70 kDa protein
SGL_RS12770	COG1587	Uroporphyrinogen-III synthase
SGL_RS12775	COG2319	Wd-40 repeat
SGL_RS12795	COG3385	transposase activity
SGL_RS12805	COG1381	Involved in DNA repair and RecF pathway recombination
SGL_RS12820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SGL_RS12840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SGL_RS12845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGL_RS12850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGL_RS12855	COG5001	Diguanylate cyclase
SGL_RS12865	COG1187	pseudouridine synthase activity
SGL_RS12870	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SGL_RS12900	COG1012	belongs to the aldehyde dehydrogenase family
SGL_RS12905	COG5002	protein histidine kinase activity
SGL_RS12910	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGL_RS12915	COG2308	Evidence 4 Homologs of previously reported genes of
SGL_RS12945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SGL_RS12955	COG0346	lactoylglutathione lyase activity
SGL_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS12970	COG0742	ribosomal rna small subunit methyltransferase
SGL_RS12975	COG0438	transferase activity, transferring glycosyl groups
SGL_RS12985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SGL_RS13005	COG1104	cysteine desulfurase activity
SGL_RS13010	COG1040	competence protein
SGL_RS13015	COG1376	ErfK ybiS ycfS ynhG family protein
SGL_RS13030	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGL_RS13040	COG3659	wide pore channel activity
SGL_RS13045	COG0477	Major facilitator Superfamily
SGL_RS13050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGL_RS13055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGL_RS13060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SGL_RS13065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGL_RS13070	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SGL_RS13075	COG2003	Belongs to the UPF0758 family
SGL_RS13080	COG1054	Belongs to the UPF0176 family
SGL_RS13090	COG0411	ABC transporter
SGL_RS13110	COG1131	(ABC) transporter
SGL_RS13120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SGL_RS13130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SGL_RS13140	COG0450	alkyl hydroperoxide reductase
SGL_RS13145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SGL_RS13155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SGL_RS13165	COG1231	oxidoreductase activity
SGL_RS13170	COG2205	protein histidine kinase activity
SGL_RS13180	COG0149	triose-phosphate isomerase activity
SGL_RS13185	COG0628	permease
SGL_RS13200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SGL_RS13205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SGL_RS13220	COG0571	ribonuclease III activity
SGL_RS13225	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SGL_RS13250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SGL_RS13270	COG3385	transposase activity
SGL_RS13290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGL_RS13315	COG1748	Saccharopine dehydrogenase
SGL_RS13325	COG0601	transmembrane transport
SGL_RS13330	COG0124	histidyl-tRNA synthetase
SGL_RS13375	COG0542	response to heat
SGL_RS13380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SGL_RS13385	COG0191	fructose-bisphosphate aldolase activity
SGL_RS13390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SGL_RS13410	COG0793	Belongs to the peptidase S41A family
SGL_RS13415	COG1850	ribulose-bisphosphate carboxylase activity
SGL_RS13425	COG4451	ribulose bisphosphate carboxylase, small
SGL_RS13435	COG1285	pathogenesis
SGL_RS13445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SGL_RS13450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SGL_RS13460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGL_RS13465	COG0114	fumarate hydratase activity
SGL_RS13490	COG0436	Aminotransferase
SGL_RS13495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGL_RS13500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGL_RS13505	COG0616	signal peptide processing
SGL_RS13510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SGL_RS13520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGL_RS13520	COG0519	Catalyzes the synthesis of GMP from XMP
SGL_RS13530	COG1968	undecaprenyl-diphosphatase activity
SGL_RS13550	COG5322	oxidoreductase activity
SGL_RS13555	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SGL_RS13565	COG0751	glycine-tRNA ligase activity
SGL_RS13580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SGL_RS13585	COG5002	protein histidine kinase activity
SGL_RS13590	COG0445	tRNA wobble uridine modification
SGL_RS13610	COG3794	PFAM blue (type 1) copper domain protein
SGL_RS13625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGL_RS13630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SGL_RS13635	COG0805	protein transport
SGL_RS13640	COG2084	Dehydrogenase
SGL_RS13655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SGL_RS13665	COG0586	Pfam SNARE associated Golgi protein
SGL_RS13670	COG3118	belongs to the thioredoxin family
SGL_RS13675	COG3751	2OG-Fe(II) oxygenase superfamily
SGL_RS13680	COG0459	protein refolding
SGL_RS13685	COG1131	(ABC) transporter
SGL_RS13710	COG4399	Belongs to the UPF0754 family
SGL_RS13715	COG0824	Thioesterase
SGL_RS13720	COG4948	Mandelate Racemase Muconate Lactonizing
SGL_RS13725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGL_RS13730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SGL_RS13735	COG0511	ligase activity, forming carbon-carbon bonds
SGL_RS13740	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SGL_RS13765	COG0277	FAD linked oxidase domain protein
SGL_RS13785	COG0436	Aminotransferase
SGL_RS13790	COG0372	Belongs to the citrate synthase family
SGL_RS13795	COG2062	phosphohistidine phosphatase, SixA
SGL_RS13800	COG0596	Alpha beta hydrolase
SGL_RS13815	COG1234	tRNA 3'-trailer cleavage
SGL_RS13830	COG0788	formyltetrahydrofolate deformylase activity
SGL_RS13850	COG0625	glutathione transferase activity
SGL_RS13860	COG0440	acetolactate synthase activity
SGL_RS13870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SGL_RS13875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SGL_RS13885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SGL_RS13890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGL_RS13900	COG0628	permease
SGL_RS13935	COG0628	permease
SGL_RS13940	COG0443	Heat shock 70 kDa protein
SGL_RS13945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SGL_RS13950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SGL_RS13955	COG0116	Belongs to the methyltransferase superfamily
SGL_RS13965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGL_RS13965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGL_RS13970	COG0612	Peptidase, M16
SGL_RS13975	COG0489	protein tyrosine kinase activity
SGL_RS13980	COG0439	Biotin carboxylase
SGL_RS13985	COG3224	Antibiotic biosynthesis monooxygenase
SGL_RS13990	COG0590	tRNA wobble adenosine to inosine editing
SGL_RS13995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGL_RS14010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SGL_RS14025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGL_RS14030	COG4251	negative regulation of phosphorylation
SGL_RS14035	COG0784	Response regulator, receiver
SGL_RS14040	COG0556	nucleotide-excision repair
SGL_RS14065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SGL_RS14070	COG2890	protein-(glutamine-N5) methyltransferase activity
SGL_RS14075	COG0525	valine-tRNA ligase activity
SGL_RS14080	COG5002	protein histidine kinase activity
SGL_RS14090	COG0728	peptidoglycan biosynthetic process
SGL_RS14105	COG0318	PFAM AMP-dependent synthetase and ligase
SGL_RS14120	COG0460	homoserine dehydrogenase
SGL_RS14125	COG2091	lysine biosynthetic process via aminoadipic acid
SGL_RS14135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SGL_RS14155	COG0475	glutathione-regulated potassium exporter activity
SGL_RS14170	COG4232	protein-disulfide reductase activity
SGL_RS14180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGL_RS14185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGL_RS14190	COG0581	inorganic phosphate transmembrane transporter activity
SGL_RS14205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGL_RS14220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SGL_RS14225	COG1842	Phage shock protein A
SGL_RS14240	COG0653	protein targeting
SGL_RS14245	COG2119	membrane
SGL_RS14255	COG2255	four-way junction helicase activity
SGL_RS14260	COG2022	thiamine diphosphate biosynthetic process
SGL_RS14260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGL_RS14270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGL_RS14280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SGL_RS14290	COG0752	glycyl-tRNA synthetase alpha subunit
SGL_RS14295	COG0668	transmembrane transport
SGL_RS14300	COG5002	protein histidine kinase activity
SGL_RS14315	COG2211	Major facilitator Superfamily
SGL_RS14330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGL_RS14335	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SGL_RS14365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGL_RS14375	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SGL_RS14385	COG0745	RESPONSE REGULATOR receiver
SGL_RS14390	COG0406	alpha-ribazole phosphatase activity
SGL_RS14400	COG0475	glutathione-regulated potassium exporter activity
SGL_RS14400	COG0589	response to stress
SGL_RS14415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGL_RS14425	COG1122	ATPase activity
SGL_RS14435	COG0310	cobalt ion transport
SGL_RS14460	COG0438	transferase activity, transferring glycosyl groups
SGL_RS14465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SGL_RS14480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGL_RS14485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SGL_RS14495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SGL_RS14505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGL_RS14520	COG1598	PFAM Uncharacterised protein family UPF0150
SGL_RS14530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGL_RS14540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SGL_RS14545	COG0302	gtp cyclohydrolase
SGL_RS14550	COG1546	Belongs to the CinA family
SGL_RS14550	COG1058	Belongs to the CinA family
SGL_RS14555	COG0792	nuclease activity
SGL_RS14565	COG2385	sporulation resulting in formation of a cellular spore
SGL_RS14565	COG2247	cell wall binding repeat
SGL_RS14570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SGL_RS14580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SGL_RS14605	COG0121	glutamine amidotransferase
SGL_RS14610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGL_RS14620	COG2048	Heterodisulfide reductase, subunit B
SGL_RS14625	COG0762	integral membrane protein
SGL_RS14635	COG4178	(ABC) transporter
SGL_RS14660	COG0824	Thioesterase
SGL_RS14665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGL_RS14690	COG2202	Pas domain
SGL_RS14690	COG2205	protein histidine kinase activity
SGL_RS14705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGL_RS14710	COG1410	methionine synthase
SGL_RS14710	COG0646	methionine synthase
SGL_RS14745	COG1410	methionine synthase
SGL_RS14745	COG0646	methionine synthase
SGL_RS14760	COG1309	transcriptional regulator
SGL_RS14765	COG0534	Mate efflux family protein
SGL_RS14780	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SGL_RS14785	COG0303	'Molybdopterin
SGL_RS14790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGL_RS14795	COG0315	cyclic pyranopterin monophosphate synthase activity
SGL_RS14795	COG0746	molybdenum cofactor guanylyltransferase activity
SGL_RS14805	COG0314	molybdopterin synthase activity
SGL_RS14815	COG0606	chelatase, subunit chli
SGL_RS14820	COG1032	radical SAM domain protein
SGL_RS14860	COG0156	8-amino-7-oxononanoate synthase activity
SGL_RS14865	COG0024	Methionine aminopeptidase
SGL_RS14875	COG0494	nUDIX hydrolase
SGL_RS14880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SGL_RS14885	COG0039	L-malate dehydrogenase activity
SGL_RS14900	COG0193	aminoacyl-tRNA hydrolase activity
SGL_RS14930	COG0024	Methionine aminopeptidase
SGL_RS14935	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SGL_RS14950	COG4243	Vitamin k epoxide reductase
SGL_RS14955	COG0426	domain, Protein
SGL_RS14955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGL_RS14960	COG0613	PHP domain protein
SGL_RS14965	COG2251	uridine kinase activity
SGL_RS14970	COG3063	Type IV pilus biogenesis stability protein PilW
SGL_RS14975	COG0023	Translation Initiation Factor
SGL_RS15015	COG2954	triphosphatase activity
SGL_RS15020	COG2124	cytochrome p450
SGL_RS15030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGL_RS15045	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SGL_RS15070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGL_RS15080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGL_RS15085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SGL_RS15095	COG3706	GGDEF domain
SGL_RS15095	COG2203	Gaf domain
SGL_RS15095	COG4251	negative regulation of phosphorylation
SGL_RS15095	COG5001	Diguanylate cyclase
SGL_RS15100	COG0659	secondary active sulfate transmembrane transporter activity
SGL_RS15105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGL_RS15120	COG0305	Participates in initiation and elongation during chromosome replication
SGL_RS15120	COG1372	Participates in initiation and elongation during chromosome replication
SGL_RS15125	COG0714	Associated with various cellular activities
SGL_RS15140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGL_RS15145	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SGL_RS15150	COG2226	methyltransferase
SGL_RS15155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SGL_RS15160	COG0154	amidase activity
SGL_RS15175	COG5001	Diguanylate cyclase
SGL_RS15175	COG4251	negative regulation of phosphorylation
SGL_RS15175	COG3706	GGDEF domain
SGL_RS15175	COG2203	Gaf domain
SGL_RS15180	COG0617	tRNA 3'-terminal CCA addition
SGL_RS15190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGL_RS15205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SGL_RS15215	COG1959	2 iron, 2 sulfur cluster binding
SGL_RS15220	COG4251	negative regulation of phosphorylation
SGL_RS15220	COG2203	Gaf domain
SGL_RS15220	COG3706	GGDEF domain
SGL_RS15220	COG5001	Diguanylate cyclase
SGL_RS15225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGL_RS15235	COG0357	Ribosomal RNA small subunit methyltransferase G
SGL_RS15250	COG0719	Fe-S assembly protein
SGL_RS15255	COG0396	ATPase activity
SGL_RS15260	COG0719	Fe-S assembly protein
SGL_RS15265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGL_RS15270	COG0003	Pfam Anion-transporting ATPase
SGL_RS15285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SGL_RS15290	COG0720	synthase
SGL_RS15305	COG0328	RNA-DNA hybrid ribonuclease activity
SGL_RS15310	COG0745	RESPONSE REGULATOR receiver
SGL_RS15315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGL_RS15320	COG0513	Belongs to the DEAD box helicase family
SGL_RS15325	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGL_RS15330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SGL_RS15335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGL_RS15340	COG0443	Heat shock 70 kDa protein
SGL_RS15350	COG2226	methyltransferase
SGL_RS15355	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SGL_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
SGL_RS15365	COG1216	Glycosyl transferase, family 2
SGL_RS15370	COG0484	heat shock protein binding
SGL_RS15380	COG0659	secondary active sulfate transmembrane transporter activity
SGL_RS15390	COG1131	(ABC) transporter
SGL_RS15395	COG0131	Imidazoleglycerol-phosphate dehydratase
SGL_RS15405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGL_RS15410	COG4251	negative regulation of phosphorylation
SGL_RS15415	COG2197	response regulator
SGL_RS15430	COG0515	serine threonine protein kinase
SGL_RS15440	COG1028	Short-chain dehydrogenase reductase Sdr
SGL_RS15455	COG0436	Aminotransferase
SGL_RS15460	COG0586	Pfam SNARE associated Golgi protein
SGL_RS15465	COG3264	Mechanosensitive ion channel
SGL_RS15465	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SGL_RS15480	COG0848	biopolymer transport protein
SGL_RS15485	COG0848	biopolymer transport protein
SGL_RS15490	COG0811	peptide transport
SGL_RS15495	COG1840	ABC-type Fe3 transport system, periplasmic component
SGL_RS15505	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS15510	COG2205	protein histidine kinase activity
SGL_RS15520	COG0456	acetyltransferase
SGL_RS15525	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGL_RS15530	COG0047	phosphoribosylformylglycinamidine synthase activity
SGL_RS15555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SGL_RS15560	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SGL_RS15565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SGL_RS15570	COG0628	permease
SGL_RS15585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGL_RS15590	COG0837	glucose binding
SGL_RS15595	COG1132	(ABC) transporter
SGL_RS15615	COG0668	transmembrane transport
SGL_RS15620	COG1492	cobalamin metabolic process
SGL_RS15640	COG0469	pyruvate kinase activity
SGL_RS15645	COG2081	HI0933 family
SGL_RS15650	COG3118	belongs to the thioredoxin family
SGL_RS15665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SGL_RS15680	COG0463	Glycosyl transferase, family 2
SGL_RS15680	COG0457	Tetratricopeptide repeat
SGL_RS15695	COG0004	ammonium transporteR
SGL_RS15700	COG0800	Aldolase
SGL_RS15710	COG1480	7TM receptor with intracellular HD hydrolase
SGL_RS15715	COG2304	oxidoreductase activity
SGL_RS15725	COG1192	Involved in chromosome partitioning
SGL_RS15740	COG1473	amidohydrolase
SGL_RS15750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SGL_RS15775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SGL_RS15780	COG0784	Response regulator, receiver
SGL_RS15780	COG2205	protein histidine kinase activity
SGL_RS15785	COG1192	Involved in chromosome partitioning
SGL_RS15805	COG0745	RESPONSE REGULATOR receiver
SGL_RS15825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SGL_RS15835	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SGL_RS15845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SGL_RS15860	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SGL_RS15865	COG2894	cell division
SGL_RS15870	COG0850	regulation of cytokinetic process
SGL_RS15875	COG1716	ATPase activity
SGL_RS15890	COG0574	Belongs to the PEP-utilizing enzyme family
SGL_RS15890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGL_RS15910	COG0398	Pfam SNARE associated Golgi protein
SGL_RS15915	COG0737	Belongs to the 5'-nucleotidase family
SGL_RS15920	COG0454	-acetyltransferase
SGL_RS15935	COG1032	radical SAM domain protein
SGL_RS15960	COG4585	Histidine kinase
SGL_RS15965	COG2197	response regulator
SGL_RS15970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SGL_RS15970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SGL_RS15975	COG2267	carboxylic ester hydrolase activity
SGL_RS15980	COG4221	oxidoreductase activity
SGL_RS16015	COG0024	Methionine aminopeptidase
SGL_RS16030	COG1056	cytidyltransferase-related domain
SGL_RS16030	COG1051	belongs to the nudix hydrolase family
SGL_RS16045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGL_RS16050	COG5002	protein histidine kinase activity
SGL_RS16075	COG2814	Major facilitator Superfamily
SGL_RS16085	COG2217	Heavy metal translocating P-type atpase
SGL_RS16090	COG1742	UPF0060 membrane protein
SGL_RS16095	COG0640	Transcriptional regulator
SGL_RS16100	COG2217	Heavy metal translocating P-type atpase
SGL_RS16105	COG5002	protein histidine kinase activity
SGL_RS16110	COG0745	RESPONSE REGULATOR receiver
SGL_RS16135	COG2144	transferase activity, transferring acyl groups
SGL_RS16160	COG2072	flavoprotein involved in K transport
SGL_RS16165	COG2197	response regulator
SGL_RS16175	COG3706	GGDEF domain
SGL_RS16175	COG5001	Diguanylate cyclase
SGL_RS16175	COG2203	Gaf domain
SGL_RS16175	COG4251	negative regulation of phosphorylation
SGL_RS16180	COG0842	Transport permease protein
SGL_RS16180	COG1716	ATPase activity
SGL_RS16180	COG1131	(ABC) transporter
SGL_RS16190	COG0515	serine threonine protein kinase
SGL_RS16190	COG4991	sh3 domain protein
SGL_RS16190	COG3064	Membrane
SGL_RS16210	COG2954	triphosphatase activity
SGL_RS16225	COG0789	Transcriptional regulator
SGL_RS16270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGL_RS16275	COG0598	Magnesium transport protein CorA
SGL_RS16290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGL_RS16290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SGL_RS16325	COG0251	oxidation-reduction process
SGL_RS16330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SGL_RS16335	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SGL_RS16340	COG0392	lysyltransferase activity
SGL_RS16360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SGL_RS16370	COG0343	queuine tRNA-ribosyltransferase activity
SGL_RS16385	COG2886	Uncharacterised protein family (UPF0175)
SGL_RS16390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGL_RS16395	COG0668	transmembrane transport
SGL_RS16400	COG0205	6-phosphofructokinase activity
SGL_RS16420	COG0674	pyruvate-flavodoxin oxidoreductase activity
SGL_RS16420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SGL_RS16420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SGL_RS16420	COG1013	pyruvate-flavodoxin oxidoreductase activity
SGL_RS16430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGL_RS16435	COG0725	ABC transporter, periplasmic molybdate-binding protein
SGL_RS16460	COG0438	transferase activity, transferring glycosyl groups
SGL_RS16475	COG0784	Response regulator, receiver
SGL_RS16475	COG0643	Histidine kinase
SGL_RS16475	COG2198	Histidine kinase
SGL_RS16480	COG0840	transmembrane signaling receptor activity
SGL_RS16485	COG2203	Gaf domain
SGL_RS16485	COG0840	transmembrane signaling receptor activity
SGL_RS16500	COG0784	Response regulator, receiver
SGL_RS16510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGL_RS16515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGL_RS16520	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SGL_RS16525	COG1597	lipid kinase activity
SGL_RS16525	COG1803	Methylglyoxal synthase
SGL_RS16530	COG0436	Aminotransferase
SGL_RS16555	COG0857	belongs to the CobB CobQ family
SGL_RS16560	COG0583	DNA-binding transcription factor activity
SGL_RS16565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGL_RS16570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGL_RS16575	COG3659	wide pore channel activity
SGL_RS16580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGL_RS16580	COG1116	anion transmembrane transporter activity
SGL_RS16585	COG1116	anion transmembrane transporter activity
SGL_RS16590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS16595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGL_RS16605	COG0724	RNA recognition motif
SGL_RS16610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SGL_RS16615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGL_RS16620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SGL_RS16625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGL_RS16630	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SGL_RS16640	COG1653	transport
SGL_RS16645	COG1175	transmembrane transport
SGL_RS16650	COG0395	ABC-type sugar transport system, permease component
SGL_RS16660	COG2205	protein histidine kinase activity
SGL_RS16665	COG0741	lytic transglycosylase activity
SGL_RS16675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGL_RS16690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SGL_RS16695	COG0598	Magnesium transport protein CorA
SGL_RS16700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGL_RS16705	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SGL_RS16710	COG0019	diaminopimelate decarboxylase activity
SGL_RS16715	COG1160	GTP binding
SGL_RS16720	COG0018	arginyl-trna synthetase
SGL_RS16725	COG0463	Glycosyl transferase, family 2
SGL_RS16735	COG0740	serine-type endopeptidase activity
SGL_RS16740	COG0133	tryptophan synthase activity
SGL_RS16750	COG1136	(ABC) transporter
SGL_RS16755	COG2314	TM2 domain
SGL_RS16775	COG0017	Asparaginyl-tRNA synthetase
SGL_RS16795	COG0569	domain protein
SGL_RS16800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGL_RS16805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGL_RS16810	COG0629	single-stranded DNA binding
SGL_RS16820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SGL_RS16830	COG1192	Involved in chromosome partitioning
SGL_RS16840	COG2119	membrane
SGL_RS16845	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SGL_RS16850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SGL_RS16860	COG1162	GTPase activity
SGL_RS16870	COG0484	heat shock protein binding
SGL_RS16875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SGL_RS16880	COG1218	3'(2'),5'-bisphosphate nucleotidase
SGL_RS16890	COG0134	indole-3-glycerol-phosphate synthase activity
SGL_RS16895	COG0004	ammonium transporteR
SGL_RS16900	COG0569	domain protein
SGL_RS16905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SGL_RS16910	COG0740	serine-type endopeptidase activity
SGL_RS16915	COG0544	peptidyl-prolyl cis-trans isomerase activity
SGL_RS16920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGL_RS16925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGL_RS16930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SGL_RS16940	COG0237	dephospho-CoA kinase activity
SGL_RS16955	COG1994	Peptidase M50
SGL_RS16955	COG0517	IMP dehydrogenase activity
SGL_RS16960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGL_RS16980	COG0525	valine-tRNA ligase activity
SGL_RS16985	COG0713	ATP synthesis coupled electron transport
SGL_RS16990	COG0839	Belongs to the complex I subunit 6 family
SGL_RS16995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SGL_RS17000	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SGL_RS17005	COG0167	dihydroorotate dehydrogenase activity
SGL_RS17010	COG2166	iron-sulfur cluster assembly
SGL_RS17015	COG1070	Carbohydrate kinase
SGL_RS17040	COG0308	aminopeptidase N
SGL_RS17045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SGL_RS17050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGL_RS17055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGL_RS17065	COG2193	ferroxidase activity
SGL_RS17075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SGL_RS17085	COG1834	amidinotransferase
SGL_RS17090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SGL_RS17120	COG0745	RESPONSE REGULATOR receiver
SGL_RS17125	COG0483	inositol monophosphate 1-phosphatase activity
SGL_RS17140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SGL_RS17145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGL_RS17150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SGL_RS17155	COG4208	sulfate ABC transporter
SGL_RS17160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGL_RS17165	COG2165	general secretion pathway protein
SGL_RS17180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SGL_RS17195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SGL_RS17200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGL_RS17205	COG0731	radical SAM domain protein
SGL_RS17210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SGL_RS17215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SGL_RS17225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SGL_RS17230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGL_RS17245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGL_RS17300	COG0339	signal peptide processing
SGL_RS17305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SGL_RS17330	COG1166	arginine decarboxylase activity
SGL_RS17340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGL_RS17360	COG1049	propionate catabolic process, 2-methylcitrate cycle
SGL_RS17380	COG0067	glutamate synthase
SGL_RS17380	COG0069	glutamate synthase activity
SGL_RS17380	COG0070	glutamate synthase
SGL_RS17385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGL_RS17390	COG0505	Belongs to the CarA family
SGL_RS17400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SGL_RS17405	COG0579	oxidoreductase
SGL_RS17415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGL_RS17420	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SGL_RS17425	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SGL_RS17430	COG3001	Fructosamine kinase
SGL_RS17440	COG1191	sigma factor activity
SGL_RS17445	COG0316	Belongs to the HesB IscA family
SGL_RS17450	COG0463	Glycosyl transferase, family 2
SGL_RS17455	COG2319	Wd-40 repeat
SGL_RS17470	COG1691	(AIR) carboxylase
SGL_RS17475	COG0739	heme binding
SGL_RS17495	COG1496	oxidoreductase activity
SGL_RS17500	COG2052	Domain of unknown function (DUF370)
SGL_RS17505	COG3264	Mechanosensitive ion channel
SGL_RS17505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SGL_RS17545	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SGL_RS17560	COG0363	glucosamine-6-phosphate deaminase activity
SGL_RS17585	COG3385	transposase activity
SGL_RS17590	COG5001	Diguanylate cyclase
SGL_RS17590	COG4251	negative regulation of phosphorylation
SGL_RS17590	COG3706	GGDEF domain
SGL_RS17590	COG2203	Gaf domain
SGL_RS17600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGL_RS17620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGL_RS17625	COG3300	MHYT domain
SGL_RS17625	COG5001	Diguanylate cyclase
SGL_RS17635	COG3842	ATPase activity
SGL_RS17645	COG1543	Belongs to the glycosyl hydrolase 57 family
SGL_RS17655	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SGL_RS17660	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGL_RS17670	COG0457	Tetratricopeptide repeat
SGL_RS17675	COG0148	phosphopyruvate hydratase activity
SGL_RS17685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SGL_RS17700	COG0825	malonyl-CoA metabolic process
SGL_RS17725	COG1598	PFAM Uncharacterised protein family UPF0150
SGL_RS17755	COG4251	negative regulation of phosphorylation
SGL_RS17760	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SGL_RS17785	COG2994	toxin metabolic process
SGL_RS17800	COG0170	dolichyl monophosphate biosynthetic process
SGL_RS17805	COG1473	amidohydrolase
SGL_RS17810	COG3659	wide pore channel activity
SGL_RS17830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGL_RS17835	COG3706	GGDEF domain
SGL_RS17835	COG5001	Diguanylate cyclase
SGL_RS17835	COG2203	Gaf domain
SGL_RS17835	COG4251	negative regulation of phosphorylation
SGL_RS17860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SGL_RS17890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SGL_RS17905	COG2197	response regulator
SGL_RS17950	COG2153	protein acetylation
SGL_RS18000	COG4581	dead DEAH box helicase
SGL_RS18010	COG0322	excinuclease ABC activity
SGL_RS18015	COG0129	dihydroxy-acid dehydratase activity
SGL_RS18020	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SGL_RS18050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SGL_RS18055	COG0546	phosphoglycolate phosphatase activity
SGL_RS18085	COG0326	Molecular chaperone. Has ATPase activity
SGL_RS18090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SGL_RS18105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SGL_RS18110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SGL_RS18120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SGL_RS18155	COG0723	plastoquinol--plastocyanin reductase activity
SGL_RS18170	COG1842	Phage shock protein A
SGL_RS18190	COG1064	alcohol dehydrogenase
SGL_RS18195	COG0137	argininosuccinate synthase activity
SGL_RS18210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SGL_RS18215	COG1357	PFAM Pentapeptide repeats (8 copies)
SGL_RS18235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGL_RS18250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SGL_RS18255	COG0549	Belongs to the carbamate kinase family
SGL_RS18275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SGL_RS18280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SGL_RS18285	COG1136	(ABC) transporter
SGL_RS18285	COG0577	efflux transmembrane transporter activity
SGL_RS18290	COG0735	belongs to the Fur family
SGL_RS18300	COG0138	bifunctional purine biosynthesis protein purh
SGL_RS18320	COG0515	serine threonine protein kinase
SGL_RS18345	COG0587	DNA-directed DNA polymerase activity
SGL_RS18350	COG0481	GTPase activity
SGL_RS18355	COG0435	Glutathione S-transferase
SGL_RS18375	COG0140	phosphoribosyl-ATP diphosphatase activity
SGL_RS18375	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SGL_RS18380	COG0523	cobalamin synthesis protein