locus-tag	class	description
AOY38_RS00005	COG0142	geranyltranstransferase activity
AOY38_RS00010	COG1187	pseudouridine synthase activity
AOY38_RS00020	COG0515	serine threonine protein kinase
AOY38_RS00025	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AOY38_RS00030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY38_RS00035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AOY38_RS00045	COG1166	arginine decarboxylase activity
AOY38_RS00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOY38_RS00060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOY38_RS00065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOY38_RS00070	COG1120	ATPase activity
AOY38_RS00075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOY38_RS00085	COG4977	sequence-specific DNA binding
AOY38_RS00110	COG2207	Transcriptional regulator
AOY38_RS00115	COG2226	methyltransferase
AOY38_RS00125	COG0848	biopolymer transport protein
AOY38_RS00130	COG0811	peptide transport
AOY38_RS00145	COG1132	(ABC) transporter
AOY38_RS00160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOY38_RS00165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOY38_RS00175	COG1132	(ABC) transporter
AOY38_RS00220	COG0409	Hydrogenase expression formation protein
AOY38_RS00225	COG1091	dTDP-4-dehydrorhamnose reductase activity
AOY38_RS00230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOY38_RS00235	COG0297	glycogen (starch) synthase activity
AOY38_RS00250	COG1131	(ABC) transporter
AOY38_RS00265	COG2318	DinB family
AOY38_RS00270	COG4106	trans-aconitate 2-methyltransferase activity
AOY38_RS00285	COG1214	PFAM Peptidase M22, glycoprotease
AOY38_RS00305	COG1615	UPF0182 protein
AOY38_RS00320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AOY38_RS00325	COG0563	adenylate kinase activity
AOY38_RS00330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOY38_RS00350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOY38_RS00365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOY38_RS00370	COG0194	GDP metabolic process
AOY38_RS00375	COG0406	alpha-ribazole phosphatase activity
AOY38_RS00385	COG0730	response to heat
AOY38_RS00390	COG1413	lyase activity
AOY38_RS00405	COG0330	HflC and HflK could
AOY38_RS00410	COG1530	ribonuclease E activity
AOY38_RS00415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOY38_RS00420	COG0494	nUDIX hydrolase
AOY38_RS00425	COG1185	polyribonucleotide nucleotidyltransferase activity
AOY38_RS00430	COG0681	Belongs to the peptidase S26 family
AOY38_RS00445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOY38_RS00455	COG1401	restriction endodeoxyribonuclease activity
AOY38_RS00460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOY38_RS00465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOY38_RS00510	COG1104	cysteine desulfurase activity
AOY38_RS00535	COG0582	viral genome integration into host DNA
AOY38_RS00545	COG2022	thiamine diphosphate biosynthetic process
AOY38_RS00545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOY38_RS00560	COG5002	protein histidine kinase activity
AOY38_RS00570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOY38_RS00590	COG0704	Plays a role in the regulation of phosphate uptake
AOY38_RS00595	COG0779	Required for maturation of 30S ribosomal subunits
AOY38_RS00600	COG0195	Participates in both transcription termination and antitermination
AOY38_RS00605	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AOY38_RS00645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOY38_RS00655	COG0011	TIGRFAM Protein of
AOY38_RS00665	COG0589	response to stress
AOY38_RS00675	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOY38_RS00680	COG0010	Belongs to the arginase family
AOY38_RS00685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOY38_RS00725	COG2099	Precorrin-6x reductase
AOY38_RS00740	COG1007	ATP synthesis coupled electron transport
AOY38_RS00755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOY38_RS00760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOY38_RS00765	COG0426	domain, Protein
AOY38_RS00765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOY38_RS00775	COG0426	domain, Protein
AOY38_RS00775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOY38_RS00785	COG0793	Belongs to the peptidase S41A family
AOY38_RS00790	COG0009	L-threonylcarbamoyladenylate synthase
AOY38_RS00795	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AOY38_RS00800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AOY38_RS00805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AOY38_RS00810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOY38_RS00815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOY38_RS00820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOY38_RS00825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOY38_RS00830	COG0356	it plays a direct role in the translocation of protons across the membrane
AOY38_RS00840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOY38_RS00855	COG0714	Associated with various cellular activities
AOY38_RS00860	COG0316	Belongs to the HesB IscA family
AOY38_RS00865	COG0697	spore germination
AOY38_RS00875	COG1127	ABC transporter
AOY38_RS00885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOY38_RS00910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOY38_RS00925	COG0163	prenyltransferase activity
AOY38_RS00935	COG0589	response to stress
AOY38_RS00945	COG1716	ATPase activity
AOY38_RS00945	COG5001	Diguanylate cyclase
AOY38_RS00955	COG1217	gtp-binding protein TYPA
AOY38_RS00970	COG1234	tRNA 3'-trailer cleavage
AOY38_RS00980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOY38_RS00995	COG0631	protein serine/threonine phosphatase activity
AOY38_RS01000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOY38_RS01010	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AOY38_RS01015	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS01020	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS01025	COG0493	'glutamate synthase
AOY38_RS01070	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AOY38_RS01070	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AOY38_RS01085	COG1982	Orn Lys Arg decarboxylase major
AOY38_RS01090	COG0686	Belongs to the AlaDH PNT family
AOY38_RS01095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOY38_RS01115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY38_RS01125	COG0673	inositol 2-dehydrogenase activity
AOY38_RS01130	COG0700	Nucleoside recognition
AOY38_RS01135	COG2715	membrane protein required for spore maturation
AOY38_RS01140	COG1640	4-alpha-glucanotransferase
AOY38_RS01150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOY38_RS01165	COG5001	Diguanylate cyclase
AOY38_RS01165	COG4251	negative regulation of phosphorylation
AOY38_RS01165	COG3706	GGDEF domain
AOY38_RS01165	COG2203	Gaf domain
AOY38_RS01170	COG2205	protein histidine kinase activity
AOY38_RS01170	COG0784	Response regulator, receiver
AOY38_RS01185	COG1981	membrane
AOY38_RS01190	COG0175	sulfate reduction
AOY38_RS01195	COG1420	regulation of RNA biosynthetic process
AOY38_RS01205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AOY38_RS01210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOY38_RS01220	COG0003	Pfam Anion-transporting ATPase
AOY38_RS01225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOY38_RS01240	COG0484	heat shock protein binding
AOY38_RS01245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOY38_RS01255	COG1216	Glycosyl transferase, family 2
AOY38_RS01255	COG0463	Glycosyl transferase, family 2
AOY38_RS01265	COG0077	Prephenate dehydratase
AOY38_RS01265	COG1605	Chorismate mutase
AOY38_RS01275	COG4251	negative regulation of phosphorylation
AOY38_RS01275	COG5001	Diguanylate cyclase
AOY38_RS01275	COG3706	GGDEF domain
AOY38_RS01275	COG2203	Gaf domain
AOY38_RS01290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOY38_RS01320	COG0589	response to stress
AOY38_RS01325	COG2226	methyltransferase
AOY38_RS01340	COG0538	isocitrate dehydrogenase activity
AOY38_RS01345	COG4636	protein conserved in cyanobacteria
AOY38_RS01355	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS01370	COG0762	integral membrane protein
AOY38_RS01375	COG1840	ABC-type Fe3 transport system, periplasmic component
AOY38_RS01380	COG0336	Belongs to the RNA methyltransferase TrmD family
AOY38_RS01385	COG0205	6-phosphofructokinase activity
AOY38_RS01390	COG1289	transmembrane transporter activity
AOY38_RS01395	COG1555	photosystem II stabilization
AOY38_RS01405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOY38_RS01410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY38_RS01415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOY38_RS01440	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOY38_RS01445	COG0277	FAD linked oxidase domain protein
AOY38_RS01465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOY38_RS01475	COG0408	coproporphyrinogen oxidase activity
AOY38_RS01480	COG5398	heme oxygenase
AOY38_RS01490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AOY38_RS01510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOY38_RS01515	COG0672	)-iron permease
AOY38_RS01520	COG0592	DNA-directed DNA polymerase activity
AOY38_RS01525	COG0159	tryptophan synthase activity
AOY38_RS01540	COG0436	Aminotransferase
AOY38_RS01550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AOY38_RS01565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AOY38_RS01575	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AOY38_RS01580	COG0701	Predicted permease
AOY38_RS01600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AOY38_RS01605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOY38_RS01610	COG4636	protein conserved in cyanobacteria
AOY38_RS01615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOY38_RS01635	COG3206	protein involved in exopolysaccharide biosynthesis
AOY38_RS01635	COG0489	protein tyrosine kinase activity
AOY38_RS01675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOY38_RS01715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOY38_RS01720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOY38_RS01725	COG1088	dTDP-glucose 4,6-dehydratase activity
AOY38_RS01730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY38_RS01750	COG1215	transferase activity, transferring glycosyl groups
AOY38_RS01760	COG1215	transferase activity, transferring glycosyl groups
AOY38_RS01765	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS01790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY38_RS01815	COG0297	glycogen (starch) synthase activity
AOY38_RS01820	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS01825	COG1598	PFAM Uncharacterised protein family UPF0150
AOY38_RS01835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOY38_RS01870	COG0110	maltose O-acetyltransferase activity
AOY38_RS01885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOY38_RS01895	COG3781	membrane
AOY38_RS01900	COG0045	succinate-CoA ligase (ADP-forming) activity
AOY38_RS01905	COG0861	Integral membrane protein TerC family
AOY38_RS01910	COG2268	Band 7 protein
AOY38_RS01915	COG0463	Glycosyl transferase, family 2
AOY38_RS01920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOY38_RS01925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOY38_RS01930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AOY38_RS01935	COG0004	ammonium transporteR
AOY38_RS01940	COG0745	RESPONSE REGULATOR receiver
AOY38_RS01955	COG0737	Belongs to the 5'-nucleotidase family
AOY38_RS01965	COG0529	Catalyzes the synthesis of activated sulfate
AOY38_RS01970	COG0811	peptide transport
AOY38_RS01975	COG0848	biopolymer transport protein
AOY38_RS01980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOY38_RS01980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOY38_RS01990	COG0530	calcium, potassium:sodium antiporter activity
AOY38_RS01995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOY38_RS02010	COG0745	RESPONSE REGULATOR receiver
AOY38_RS02015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOY38_RS02020	COG1234	tRNA 3'-trailer cleavage
AOY38_RS02045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AOY38_RS02050	COG5001	Diguanylate cyclase
AOY38_RS02050	COG2203	Gaf domain
AOY38_RS02050	COG4251	negative regulation of phosphorylation
AOY38_RS02050	COG3706	GGDEF domain
AOY38_RS02060	COG3273	potassium ion transport
AOY38_RS02060	COG0471	metal ion transport
AOY38_RS02090	COG3854	ATPases associated with a variety of cellular activities
AOY38_RS02095	COG0352	thiamine-phosphate diphosphorylase activity
AOY38_RS02100	COG0434	BtpA family
AOY38_RS02125	COG0564	pseudouridine synthase activity
AOY38_RS02130	COG2203	Gaf domain
AOY38_RS02130	COG5001	Diguanylate cyclase
AOY38_RS02130	COG4251	negative regulation of phosphorylation
AOY38_RS02130	COG3706	GGDEF domain
AOY38_RS02140	COG0475	glutathione-regulated potassium exporter activity
AOY38_RS02175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOY38_RS02180	COG1733	regulation of RNA biosynthetic process
AOY38_RS02185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOY38_RS02225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AOY38_RS02240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY38_RS02250	COG1487	ribonuclease activity
AOY38_RS02270	COG2361	Protein of unknown function DUF86
AOY38_RS02285	COG0070	glutamate synthase
AOY38_RS02285	COG0069	glutamate synthase activity
AOY38_RS02285	COG0067	glutamate synthase
AOY38_RS02300	COG2133	pyrroloquinoline quinone binding
AOY38_RS02305	COG1797	cobyrinic acid a,c-diamide synthase activity
AOY38_RS02310	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOY38_RS02315	COG1022	Amp-dependent synthetase and ligase
AOY38_RS02320	COG0784	Response regulator, receiver
AOY38_RS02335	COG2203	Gaf domain
AOY38_RS02335	COG0840	transmembrane signaling receptor activity
AOY38_RS02340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY38_RS02345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOY38_RS02350	COG2203	Gaf domain
AOY38_RS02350	COG3706	GGDEF domain
AOY38_RS02350	COG5001	Diguanylate cyclase
AOY38_RS02350	COG4251	negative regulation of phosphorylation
AOY38_RS02355	COG0419	ATPase involved in DNA repair
AOY38_RS02360	COG0484	heat shock protein binding
AOY38_RS02365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOY38_RS02375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOY38_RS02400	COG1429	ligase activity, forming nitrogen-metal bonds
AOY38_RS02415	COG3956	TIGRFAM MazG family protein
AOY38_RS02425	COG5002	protein histidine kinase activity
AOY38_RS02440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOY38_RS02455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AOY38_RS02460	COG1247	-acetyltransferase
AOY38_RS02465	COG0174	glutamine synthetase
AOY38_RS02475	COG5001	Diguanylate cyclase
AOY38_RS02475	COG4251	negative regulation of phosphorylation
AOY38_RS02475	COG3706	GGDEF domain
AOY38_RS02475	COG2203	Gaf domain
AOY38_RS02485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOY38_RS02490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOY38_RS02505	COG2310	stress, protein
AOY38_RS02510	COG0076	glutamate decarboxylase activity
AOY38_RS02525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY38_RS02530	COG0829	nickel cation binding
AOY38_RS02545	COG1045	serine acetyltransferase
AOY38_RS02560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AOY38_RS02575	COG0271	Belongs to the BolA IbaG family
AOY38_RS02580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOY38_RS02585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AOY38_RS02590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOY38_RS02595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOY38_RS02605	COG0804	urea catabolic process
AOY38_RS02620	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS02640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AOY38_RS02645	COG1773	rubredoxin
AOY38_RS02650	COG4447	cellulose binding
AOY38_RS02675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOY38_RS02680	COG3385	transposase activity
AOY38_RS02700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOY38_RS02710	COG3228	Belongs to the MtfA family
AOY38_RS02745	COG1121	(ABC) transporter
AOY38_RS02750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOY38_RS02765	COG1702	phosphate starvation-inducible protein PhoH
AOY38_RS02780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOY38_RS02800	COG0484	heat shock protein binding
AOY38_RS02805	COG0443	Heat shock 70 kDa protein
AOY38_RS02810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOY38_RS02845	COG3659	wide pore channel activity
AOY38_RS02855	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOY38_RS02855	COG2247	cell wall binding repeat
AOY38_RS02915	COG0768	penicillin binding
AOY38_RS02925	COG0247	lactate metabolic process
AOY38_RS02935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY38_RS02945	COG0583	DNA-binding transcription factor activity
AOY38_RS02955	COG0384	phenazine biosynthesis protein PhzF
AOY38_RS02965	COG2319	Wd-40 repeat
AOY38_RS02970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOY38_RS02995	COG0475	glutathione-regulated potassium exporter activity
AOY38_RS02995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOY38_RS03000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOY38_RS03020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOY38_RS03025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOY38_RS03040	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AOY38_RS03045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOY38_RS03060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOY38_RS03065	COG0629	single-stranded DNA binding
AOY38_RS03080	COG0668	transmembrane transport
AOY38_RS03090	COG0745	RESPONSE REGULATOR receiver
AOY38_RS03095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOY38_RS03095	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOY38_RS03100	COG3937	granule-associated protein
AOY38_RS03115	COG2226	methyltransferase
AOY38_RS03125	COG0681	Belongs to the peptidase S26 family
AOY38_RS03135	COG1271	oxidase subunit
AOY38_RS03140	COG1294	oxidase, subunit
AOY38_RS03145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOY38_RS03150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOY38_RS03155	COG0412	Dienelactone hydrolase
AOY38_RS03200	COG0784	Response regulator, receiver
AOY38_RS03200	COG2198	Histidine kinase
AOY38_RS03200	COG0643	Histidine kinase
AOY38_RS03205	COG2203	Gaf domain
AOY38_RS03205	COG0840	transmembrane signaling receptor activity
AOY38_RS03220	COG0784	Response regulator, receiver
AOY38_RS03230	COG0557	exoribonuclease II activity
AOY38_RS03240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY38_RS03255	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOY38_RS03265	COG5002	protein histidine kinase activity
AOY38_RS03270	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AOY38_RS03280	COG1309	transcriptional regulator
AOY38_RS03305	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOY38_RS03315	COG2385	sporulation resulting in formation of a cellular spore
AOY38_RS03325	COG3411	Ferredoxin
AOY38_RS03330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOY38_RS03355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AOY38_RS03360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOY38_RS03365	COG0237	dephospho-CoA kinase activity
AOY38_RS03370	COG0237	dephospho-CoA kinase activity
AOY38_RS03400	COG0515	serine threonine protein kinase
AOY38_RS03405	COG0515	serine threonine protein kinase
AOY38_RS03415	COG2988	succinylglutamate desuccinylase activity
AOY38_RS03420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY38_RS03430	COG0739	heme binding
AOY38_RS03435	COG0587	DNA-directed DNA polymerase activity
AOY38_RS03450	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOY38_RS03480	COG1006	Multisubunit Na H antiporter MnhC subunit
AOY38_RS03485	COG0651	ATP synthesis coupled electron transport
AOY38_RS03490	COG1006	Multisubunit Na H antiporter MnhC subunit
AOY38_RS03555	COG1132	(ABC) transporter
AOY38_RS03560	COG3063	Type IV pilus biogenesis stability protein PilW
AOY38_RS03565	COG2217	Heavy metal translocating P-type atpase
AOY38_RS03570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOY38_RS03575	COG0745	RESPONSE REGULATOR receiver
AOY38_RS03585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOY38_RS03590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOY38_RS03600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOY38_RS03630	COG0557	exoribonuclease II activity
AOY38_RS03640	COG2208	phosphoserine phosphatase activity
AOY38_RS03650	COG0165	Argininosuccinate lyase
AOY38_RS03655	COG2816	NAD+ diphosphatase activity
AOY38_RS03670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOY38_RS03675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOY38_RS03680	COG1845	cytochrome c oxidase, subunit III
AOY38_RS03685	COG3118	belongs to the thioredoxin family
AOY38_RS03695	COG1116	anion transmembrane transporter activity
AOY38_RS03700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY38_RS03715	COG0375	protein maturation
AOY38_RS03720	COG0010	Belongs to the arginase family
AOY38_RS03735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOY38_RS03745	COG0495	leucyl-tRNA aminoacylation
AOY38_RS03750	COG0786	glutamate:sodium symporter activity
AOY38_RS03760	COG2205	protein histidine kinase activity
AOY38_RS03770	COG1132	(ABC) transporter
AOY38_RS03790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOY38_RS03795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOY38_RS03800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOY38_RS03825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AOY38_RS03830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOY38_RS03840	COG0254	rRNA binding
AOY38_RS03845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOY38_RS03850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AOY38_RS03855	COG0101	tRNA pseudouridine synthase activity
AOY38_RS03860	COG0203	ribosomal protein L17
AOY38_RS03865	COG0202	RNA polymerase activity
AOY38_RS03870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AOY38_RS03875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AOY38_RS03880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOY38_RS03885	COG0563	adenylate kinase activity
AOY38_RS03890	COG0201	protein transport
AOY38_RS03895	COG0200	Binds to the 23S rRNA
AOY38_RS03900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AOY38_RS03905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOY38_RS03910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AOY38_RS03915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AOY38_RS03920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AOY38_RS03925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AOY38_RS03930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AOY38_RS03935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOY38_RS03940	COG0255	Belongs to the universal ribosomal protein uL29 family
AOY38_RS03945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AOY38_RS03950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOY38_RS03955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AOY38_RS03960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOY38_RS03965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AOY38_RS03970	COG0089	rRNA binding
AOY38_RS03975	COG0088	Forms part of the polypeptide exit tunnel
AOY38_RS03980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AOY38_RS03985	COG0783	Belongs to the Dps family
AOY38_RS04005	COG2010	Cytochrome c
AOY38_RS04015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOY38_RS04020	COG0830	nickel cation binding
AOY38_RS04030	COG1131	(ABC) transporter
AOY38_RS04055	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOY38_RS04060	COG0085	RNA polymerase activity
AOY38_RS04065	COG0084	hydrolase, TatD family'
AOY38_RS04070	COG0268	Binds directly to 16S ribosomal RNA
AOY38_RS04075	COG5002	protein histidine kinase activity
AOY38_RS04085	COG0210	DNA helicase
AOY38_RS04085	COG0210	DNA helicase
AOY38_RS04090	COG1196	nuclear chromosome segregation
AOY38_RS04095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOY38_RS04115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOY38_RS04115	COG0758	DNA mediated transformation
AOY38_RS04120	COG0393	Putative heavy-metal-binding
AOY38_RS04130	COG0450	alkyl hydroperoxide reductase
AOY38_RS04135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOY38_RS04150	COG1175	transmembrane transport
AOY38_RS04160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY38_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS04185	COG3347	Dehydrogenase
AOY38_RS04205	COG5001	Diguanylate cyclase
AOY38_RS04205	COG4251	negative regulation of phosphorylation
AOY38_RS04205	COG3706	GGDEF domain
AOY38_RS04205	COG2203	Gaf domain
AOY38_RS04210	COG0745	RESPONSE REGULATOR receiver
AOY38_RS04215	COG0784	Response regulator, receiver
AOY38_RS04225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOY38_RS04235	COG2239	Acts as a magnesium transporter
AOY38_RS04265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOY38_RS04270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOY38_RS04275	COG1799	cell septum assembly
AOY38_RS04280	COG0662	Cupin 2, conserved barrel domain protein
AOY38_RS04280	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AOY38_RS04295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AOY38_RS04300	COG0459	protein refolding
AOY38_RS04320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOY38_RS04325	COG0222	ribosome binding
AOY38_RS04330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOY38_RS04335	COG0081	regulation of translation
AOY38_RS04340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOY38_RS04345	COG0250	Participates in transcription elongation, termination and antitermination
AOY38_RS04350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOY38_RS04360	COG0335	large ribosomal subunit rRNA binding
AOY38_RS04390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY38_RS04400	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOY38_RS04410	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOY38_RS04420	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS04425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOY38_RS04435	COG2885	chlorophyll binding
AOY38_RS04440	COG2885	chlorophyll binding
AOY38_RS04450	COG1132	(ABC) transporter
AOY38_RS04460	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS04470	COG0745	RESPONSE REGULATOR receiver
AOY38_RS04475	COG0022	dehydrogenase e1 component
AOY38_RS04475	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOY38_RS04480	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS04485	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS04490	COG1929	Belongs to the glycerate kinase type-1 family
AOY38_RS04495	COG3659	wide pore channel activity
AOY38_RS04500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOY38_RS04505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOY38_RS04510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOY38_RS04540	COG0776	regulation of translation
AOY38_RS04555	COG0514	ATP-dependent DNA helicase (RecQ)
AOY38_RS04565	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AOY38_RS04570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOY38_RS04580	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AOY38_RS04630	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS04635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOY38_RS04640	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOY38_RS04645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY38_RS04660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOY38_RS04665	COG0242	peptide deformylase activity
AOY38_RS04675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOY38_RS04705	COG0243	molybdopterin cofactor binding
AOY38_RS04715	COG1116	anion transmembrane transporter activity
AOY38_RS04720	COG1116	anion transmembrane transporter activity
AOY38_RS04720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY38_RS04725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY38_RS04730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY38_RS04735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOY38_RS04745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOY38_RS04750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOY38_RS04760	COG0793	Belongs to the peptidase S41A family
AOY38_RS04770	COG0275	rRNA processing
AOY38_RS04780	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AOY38_RS04805	COG1090	epimerase
AOY38_RS04810	COG3842	ATPase activity
AOY38_RS04815	COG0515	serine threonine protein kinase
AOY38_RS04825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AOY38_RS04830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOY38_RS04835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOY38_RS04840	COG0659	secondary active sulfate transmembrane transporter activity
AOY38_RS04845	COG0589	response to stress
AOY38_RS04850	COG1233	COG1233 Phytoene dehydrogenase and related
AOY38_RS04865	COG1053	succinate dehydrogenase
AOY38_RS04870	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOY38_RS04875	COG0537	adenosine 5'-monophosphoramidase activity
AOY38_RS04905	COG0402	S-adenosylhomocysteine deaminase activity
AOY38_RS04920	COG2267	carboxylic ester hydrolase activity
AOY38_RS04930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOY38_RS04935	COG0189	ligase activity
AOY38_RS04945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOY38_RS04950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOY38_RS04975	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOY38_RS04980	COG0312	modulator of DNA gyrase
AOY38_RS05000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOY38_RS05010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOY38_RS05010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOY38_RS05025	COG2140	Oxalate decarboxylase
AOY38_RS05030	COG0058	SHG alpha-glucan phosphorylase activity
AOY38_RS05055	COG0515	serine threonine protein kinase
AOY38_RS05075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOY38_RS05075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AOY38_RS05080	COG4999	Histidine kinase
AOY38_RS05080	COG2205	protein histidine kinase activity
AOY38_RS05080	COG3850	Histidine kinase
AOY38_RS05080	COG3437	response regulator, receiver
AOY38_RS05110	COG0546	phosphoglycolate phosphatase activity
AOY38_RS05115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOY38_RS05120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOY38_RS05145	COG0539	negative regulation of cytoplasmic translation
AOY38_RS05160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOY38_RS05165	COG1132	(ABC) transporter
AOY38_RS05170	COG0469	pyruvate kinase activity
AOY38_RS05190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOY38_RS05195	COG1268	BioY protein
AOY38_RS05200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AOY38_RS05220	COG3659	wide pore channel activity
AOY38_RS05225	COG0765	amino acid transport
AOY38_RS05235	COG0058	SHG alpha-glucan phosphorylase activity
AOY38_RS05245	COG0575	Belongs to the CDS family
AOY38_RS05270	COG1970	mechanosensitive ion channel activity
AOY38_RS05275	COG0632	four-way junction helicase activity
AOY38_RS05280	COG1836	PFAM Integral membrane protein DUF92
AOY38_RS05285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOY38_RS05290	COG0724	RNA recognition motif
AOY38_RS05295	COG0154	amidase activity
AOY38_RS05300	COG0739	heme binding
AOY38_RS05305	COG0509	glycine decarboxylation via glycine cleavage system
AOY38_RS05335	COG1316	TRANSCRIPTIONal
AOY38_RS05350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOY38_RS05365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOY38_RS05370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOY38_RS05380	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS05400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY38_RS05415	COG0322	excinuclease ABC activity
AOY38_RS05440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOY38_RS05450	COG3258	Cytochrome c
AOY38_RS05455	COG0723	plastoquinol--plastocyanin reductase activity
AOY38_RS05480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AOY38_RS05505	COG2319	Wd-40 repeat
AOY38_RS05510	COG2319	Wd-40 repeat
AOY38_RS05530	COG1082	Xylose isomerase domain protein TIM barrel
AOY38_RS05545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AOY38_RS05570	COG1366	Belongs to the anti-sigma-factor antagonist family
AOY38_RS05585	COG2208	phosphoserine phosphatase activity
AOY38_RS05585	COG2770	Histidine kinase
AOY38_RS05615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOY38_RS05620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AOY38_RS05660	COG1741	Belongs to the pirin family
AOY38_RS05670	COG1193	negative regulation of DNA recombination
AOY38_RS05675	COG0631	protein serine/threonine phosphatase activity
AOY38_RS05680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY38_RS05690	COG3937	granule-associated protein
AOY38_RS05705	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOY38_RS05710	COG3932	Exopolysaccharide synthesis, ExoD
AOY38_RS05715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOY38_RS05725	COG0360	Binds together with S18 to 16S ribosomal RNA
AOY38_RS05730	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOY38_RS05735	COG1413	lyase activity
AOY38_RS05740	COG0641	radical SAM
AOY38_RS05775	COG0083	homoserine kinase activity
AOY38_RS05785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOY38_RS05790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS05800	COG0196	riboflavin kinase activity
AOY38_RS05820	COG0180	Tryptophanyl-tRNA synthetase
AOY38_RS05825	COG1713	HD superfamily hydrolase involved in NAD metabolism
AOY38_RS05830	COG0799	negative regulation of ribosome biogenesis
AOY38_RS05840	COG0181	hydroxymethylbilane synthase activity
AOY38_RS05845	COG0427	acetyl-CoA hydrolase
AOY38_RS05850	COG0857	belongs to the CobB CobQ family
AOY38_RS05850	COG0280	phosphate acetyltransferase
AOY38_RS05860	COG1489	DNA binding
AOY38_RS05870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOY38_RS05880	COG0602	queuosine metabolic process
AOY38_RS05885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOY38_RS05890	COG0612	Peptidase, M16
AOY38_RS05895	COG0612	Peptidase, M16
AOY38_RS05905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AOY38_RS05920	COG1372	Participates in initiation and elongation during chromosome replication
AOY38_RS05920	COG0187	DNA topoisomerase II activity
AOY38_RS05935	COG0646	methionine synthase
AOY38_RS05935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOY38_RS05945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOY38_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS05980	COG2197	response regulator
AOY38_RS05985	COG4251	negative regulation of phosphorylation
AOY38_RS05985	COG5001	Diguanylate cyclase
AOY38_RS05985	COG3706	GGDEF domain
AOY38_RS05985	COG2203	Gaf domain
AOY38_RS05995	COG0616	signal peptide processing
AOY38_RS06005	COG0596	Alpha beta hydrolase
AOY38_RS06010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOY38_RS06020	COG0747	negative chemotaxis
AOY38_RS06030	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOY38_RS06070	COG4968	Prepilin-type N-terminal cleavage methylation domain
AOY38_RS06075	COG4968	Prepilin-type N-terminal cleavage methylation domain
AOY38_RS06100	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS06105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOY38_RS06110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOY38_RS06120	COG2199	diguanylate cyclase activity
AOY38_RS06125	COG0750	zinc metalloprotease
AOY38_RS06130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOY38_RS06140	COG0590	tRNA wobble adenosine to inosine editing
AOY38_RS06150	COG0415	Belongs to the DNA photolyase family
AOY38_RS06160	COG3409	Peptidoglycan-binding domain 1 protein
AOY38_RS06160	COG3429	Glucose-6-phosphate dehydrogenase subunit
AOY38_RS06170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOY38_RS06175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOY38_RS06190	COG1122	ATPase activity
AOY38_RS06195	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOY38_RS06205	COG0678	peroxiredoxin activity
AOY38_RS06245	COG1252	NADH dehydrogenase
AOY38_RS06255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOY38_RS06280	COG0415	Belongs to the DNA photolyase family
AOY38_RS06295	COG1595	DNA-templated transcription, initiation
AOY38_RS06340	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AOY38_RS06350	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AOY38_RS06355	COG3339	Conserved Protein
AOY38_RS06365	COG0312	modulator of DNA gyrase
AOY38_RS06370	COG0482	sulfurtransferase activity
AOY38_RS06385	COG0488	(ABC) transporter
AOY38_RS06390	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AOY38_RS06400	COG0284	orotidine-5'-phosphate decarboxylase activity
AOY38_RS06445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOY38_RS06455	COG0697	spore germination
AOY38_RS06490	COG0583	DNA-binding transcription factor activity
AOY38_RS06510	COG2814	Major facilitator Superfamily
AOY38_RS06515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOY38_RS06520	COG0573	inorganic phosphate transmembrane transporter activity
AOY38_RS06525	COG0581	inorganic phosphate transmembrane transporter activity
AOY38_RS06530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOY38_RS06535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOY38_RS06540	COG2154	pterin-4-alpha-carbinolamine dehydratase
AOY38_RS06565	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AOY38_RS06565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOY38_RS06570	COG1562	ergosterol biosynthetic process
AOY38_RS06575	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AOY38_RS06580	COG0831	urea catabolic process
AOY38_RS06590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOY38_RS06610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOY38_RS06615	COG0730	response to heat
AOY38_RS06625	COG2188	Transcriptional regulator
AOY38_RS06640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOY38_RS06645	COG0640	Transcriptional regulator
AOY38_RS06650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOY38_RS06655	COG1754	DNA topoisomerase type I activity
AOY38_RS06655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOY38_RS06690	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AOY38_RS06720	COG2264	protein methyltransferase activity
AOY38_RS06725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOY38_RS06740	COG0386	Belongs to the glutathione peroxidase family
AOY38_RS06745	COG0183	Belongs to the thiolase family
AOY38_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS06760	COG3850	Histidine kinase
AOY38_RS06760	COG3437	response regulator, receiver
AOY38_RS06760	COG2205	protein histidine kinase activity
AOY38_RS06760	COG4999	Histidine kinase
AOY38_RS06780	COG4242	Belongs to the peptidase S51 family
AOY38_RS06785	COG0189	ligase activity
AOY38_RS06785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOY38_RS06820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOY38_RS06825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOY38_RS06835	COG0285	dihydrofolate synthase activity
AOY38_RS06855	COG4636	protein conserved in cyanobacteria
AOY38_RS06870	COG1606	tRNA processing
AOY38_RS06880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOY38_RS06890	COG2045	Belongs to the ComB family
AOY38_RS06895	COG0778	Nitroreductase
AOY38_RS06900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOY38_RS06910	COG0516	GMP reductase activity
AOY38_RS06915	COG0395	ABC-type sugar transport system, permease component
AOY38_RS06920	COG3268	Saccharopine dehydrogenase
AOY38_RS06935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOY38_RS06940	COG1121	(ABC) transporter
AOY38_RS06945	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOY38_RS06955	COG4251	negative regulation of phosphorylation
AOY38_RS06960	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AOY38_RS06970	COG0583	DNA-binding transcription factor activity
AOY38_RS06975	COG0025	NhaP-type Na H and K H
AOY38_RS06980	COG2197	response regulator
AOY38_RS06985	COG5002	protein histidine kinase activity
AOY38_RS06990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOY38_RS06995	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOY38_RS07005	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AOY38_RS07010	COG2205	protein histidine kinase activity
AOY38_RS07020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AOY38_RS07040	COG2385	sporulation resulting in formation of a cellular spore
AOY38_RS07045	COG0649	NAD binding
AOY38_RS07060	COG0429	hydrolase of the alpha beta-hydrolase fold
AOY38_RS07070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOY38_RS07075	COG3536	Protein conserved in bacteria
AOY38_RS07080	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AOY38_RS07085	COG0716	FMN binding
AOY38_RS07095	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOY38_RS07100	COG0012	GTP binding
AOY38_RS07105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOY38_RS07165	COG3842	ATPase activity
AOY38_RS07175	COG1840	ABC-type Fe3 transport system, periplasmic component
AOY38_RS07180	COG0222	ribosome binding
AOY38_RS07190	COG2066	Belongs to the glutaminase family
AOY38_RS07205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOY38_RS07220	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOY38_RS07225	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AOY38_RS07230	COG1333	cytochrome c biogenesis protein
AOY38_RS07245	COG1657	PFAM Prenyltransferase squalene oxidase
AOY38_RS07295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOY38_RS07305	COG1494	fructose-1,6-bisphosphatase
AOY38_RS07320	COG2346	COG2346, Truncated hemoglobins
AOY38_RS07325	COG2205	protein histidine kinase activity
AOY38_RS07325	COG4999	Histidine kinase
AOY38_RS07325	COG3850	Histidine kinase
AOY38_RS07325	COG3437	response regulator, receiver
AOY38_RS07335	COG3437	response regulator, receiver
AOY38_RS07340	COG1917	Cupin 2, conserved barrel domain protein
AOY38_RS07345	COG0552	protein localization to endoplasmic reticulum
AOY38_RS07355	COG0784	Response regulator, receiver
AOY38_RS07355	COG5002	protein histidine kinase activity
AOY38_RS07355	COG2205	protein histidine kinase activity
AOY38_RS07360	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOY38_RS07370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOY38_RS07390	COG0667	Aldo Keto reductase
AOY38_RS07395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOY38_RS07405	COG0442	prolyl-tRNA aminoacylation
AOY38_RS07415	COG4372	Transposase
AOY38_RS07420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY38_RS07445	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS07450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOY38_RS07455	COG0416	fatty acid biosynthetic process
AOY38_RS07460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOY38_RS07475	COG0347	Belongs to the P(II) protein family
AOY38_RS07480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOY38_RS07505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOY38_RS07510	COG0473	3-isopropylmalate dehydrogenase activity
AOY38_RS07520	COG1575	Belongs to the MenA family. Type 1 subfamily
AOY38_RS07530	COG0656	L-ascorbic acid biosynthetic process
AOY38_RS07535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOY38_RS07565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOY38_RS07580	COG2161	toxin-antitoxin pair type II binding
AOY38_RS07585	COG4115	mRNA cleavage
AOY38_RS07600	COG3385	transposase activity
AOY38_RS07615	COG3385	transposase activity
AOY38_RS07625	COG0517	IMP dehydrogenase activity
AOY38_RS07625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOY38_RS07640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOY38_RS07650	COG1215	transferase activity, transferring glycosyl groups
AOY38_RS07675	COG1216	Glycosyl transferase, family 2
AOY38_RS07680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AOY38_RS07695	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS07720	COG0463	Glycosyl transferase, family 2
AOY38_RS07725	COG0113	porphobilinogen synthase activity
AOY38_RS07735	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOY38_RS07740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOY38_RS07770	COG0312	modulator of DNA gyrase
AOY38_RS07775	COG2890	protein-(glutamine-N5) methyltransferase activity
AOY38_RS07780	COG2205	protein histidine kinase activity
AOY38_RS07795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOY38_RS07800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOY38_RS07825	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS07835	COG2205	protein histidine kinase activity
AOY38_RS07835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY38_RS07840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AOY38_RS07845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOY38_RS07850	COG0612	Peptidase, M16
AOY38_RS07855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOY38_RS07860	COG3259	Nickel-dependent hydrogenase
AOY38_RS07875	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AOY38_RS07880	COG1034	ATP synthesis coupled electron transport
AOY38_RS07915	COG0702	epimerase
AOY38_RS07950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AOY38_RS07955	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOY38_RS07970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOY38_RS07980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOY38_RS07985	COG0673	inositol 2-dehydrogenase activity
AOY38_RS08000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOY38_RS08005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AOY38_RS08040	COG0095	Lipoate-protein ligase
AOY38_RS08060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AOY38_RS08070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOY38_RS08090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AOY38_RS08095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOY38_RS08100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOY38_RS08105	COG0457	Tetratricopeptide repeat
AOY38_RS08110	COG1160	GTP binding
AOY38_RS08130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOY38_RS08145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AOY38_RS08150	COG0052	Belongs to the universal ribosomal protein uS2 family
AOY38_RS08160	COG0387	Pfam Sodium calcium exchanger
AOY38_RS08165	COG0717	Belongs to the dCTP deaminase family
AOY38_RS08200	COG3385	transposase activity
AOY38_RS08205	COG1253	flavin adenine dinucleotide binding
AOY38_RS08215	COG3046	protein related to deoxyribodipyrimidine photolyase
AOY38_RS08220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOY38_RS08220	COG0517	IMP dehydrogenase activity
AOY38_RS08220	COG0617	tRNA 3'-terminal CCA addition
AOY38_RS08230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOY38_RS08250	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AOY38_RS08250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOY38_RS08255	COG0288	reversible hydration of carbon dioxide
AOY38_RS08260	COG1045	serine acetyltransferase
AOY38_RS08270	COG0166	Belongs to the GPI family
AOY38_RS08275	COG3239	Fatty acid desaturase
AOY38_RS08280	COG1672	PFAM Archaeal ATPase
AOY38_RS08285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOY38_RS08290	COG2010	Cytochrome c
AOY38_RS08295	COG0359	binds to the 23S rRNA
AOY38_RS08305	COG1032	radical SAM domain protein
AOY38_RS08335	COG0298	carbon dioxide binding
AOY38_RS08340	COG0109	protoheme IX farnesyltransferase activity
AOY38_RS08345	COG1612	heme a metabolic process
AOY38_RS08365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AOY38_RS08375	COG3631	Ketosteroid isomerase-related protein
AOY38_RS08385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOY38_RS08385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOY38_RS08395	COG0107	imidazoleglycerol-phosphate synthase activity
AOY38_RS08420	COG2205	protein histidine kinase activity
AOY38_RS08420	COG2202	Pas domain
AOY38_RS08440	COG3850	Histidine kinase
AOY38_RS08440	COG4999	Histidine kinase
AOY38_RS08440	COG3437	response regulator, receiver
AOY38_RS08440	COG2205	protein histidine kinase activity
AOY38_RS08450	COG4956	integral membrane protein (PIN domain superfamily)
AOY38_RS08465	COG1160	GTP binding
AOY38_RS08475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOY38_RS08490	COG0432	Pfam Uncharacterised protein family UPF0047
AOY38_RS08495	COG2197	response regulator
AOY38_RS08500	COG3842	ATPase activity
AOY38_RS08510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOY38_RS08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOY38_RS08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOY38_RS08530	COG5398	heme oxygenase
AOY38_RS08535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AOY38_RS08545	COG1316	TRANSCRIPTIONal
AOY38_RS08560	COG2770	Histidine kinase
AOY38_RS08560	COG2208	phosphoserine phosphatase activity
AOY38_RS08565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOY38_RS08575	COG0539	negative regulation of cytoplasmic translation
AOY38_RS08580	COG0358	DNA primase activity
AOY38_RS08590	COG0009	L-threonylcarbamoyladenylate synthase
AOY38_RS08610	COG0589	response to stress
AOY38_RS08635	COG2082	Precorrin-8x methylmutase
AOY38_RS08645	COG0594	ribonuclease P activity
AOY38_RS08655	COG0706	membrane insertase activity
AOY38_RS08665	COG0484	heat shock protein binding
AOY38_RS08670	COG0483	inositol monophosphate 1-phosphatase activity
AOY38_RS08675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY38_RS08690	COG0791	NLP P60 protein
AOY38_RS08705	COG0540	Belongs to the ATCase OTCase family
AOY38_RS08720	COG1215	transferase activity, transferring glycosyl groups
AOY38_RS08730	COG0300	oxidoreductase activity
AOY38_RS08730	COG3000	fatty acid hydroxylase
AOY38_RS08735	COG2211	Major facilitator Superfamily
AOY38_RS08755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY38_RS08770	COG0723	plastoquinol--plastocyanin reductase activity
AOY38_RS08775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOY38_RS08780	COG2274	protein secretion by the type I secretion system
AOY38_RS08790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOY38_RS08795	COG2192	nodulation
AOY38_RS08805	COG0772	Belongs to the SEDS family
AOY38_RS08810	COG0405	Gamma-glutamyltransferase
AOY38_RS08825	COG3659	wide pore channel activity
AOY38_RS08865	COG0037	tRNA processing
AOY38_RS08870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOY38_RS08875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS08880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS08885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS08925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY38_RS08940	COG0628	permease
AOY38_RS08955	COG0066	3-isopropylmalate dehydratase activity
AOY38_RS08960	COG0504	CTP synthase activity
AOY38_RS08975	COG2204	response regulator
AOY38_RS08985	COG0259	pyridoxamine-phosphate oxidase activity
AOY38_RS09005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOY38_RS09020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOY38_RS09025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOY38_RS09030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOY38_RS09030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOY38_RS09035	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AOY38_RS09045	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOY38_RS09050	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS09065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AOY38_RS09075	COG0051	transcription antitermination factor activity, RNA binding
AOY38_RS09080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AOY38_RS09085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOY38_RS09090	COG0049	tRNA binding
AOY38_RS09095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOY38_RS09105	COG0151	Belongs to the GarS family
AOY38_RS09115	COG0698	ribose 5-phosphate isomerase
AOY38_RS09150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOY38_RS09155	COG2046	Belongs to the sulfate adenylyltransferase family
AOY38_RS09160	COG0297	glycogen (starch) synthase activity
AOY38_RS09175	COG0644	oxidoreductase
AOY38_RS09180	COG0371	Dehydrogenase
AOY38_RS09195	COG2119	membrane
AOY38_RS09200	COG0386	Belongs to the glutathione peroxidase family
AOY38_RS09215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOY38_RS09235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOY38_RS09240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOY38_RS09255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOY38_RS09260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOY38_RS09270	COG0375	protein maturation
AOY38_RS09285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AOY38_RS09290	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AOY38_RS09295	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AOY38_RS09300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOY38_RS09305	COG1134	teichoic acid transport
AOY38_RS09330	COG1012	belongs to the aldehyde dehydrogenase family
AOY38_RS09345	COG3385	transposase activity
AOY38_RS09380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOY38_RS09390	COG1304	FMN binding
AOY38_RS09395	COG0745	RESPONSE REGULATOR receiver
AOY38_RS09405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AOY38_RS09415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOY38_RS09415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOY38_RS09420	COG4251	negative regulation of phosphorylation
AOY38_RS09420	COG2203	Gaf domain
AOY38_RS09420	COG5001	Diguanylate cyclase
AOY38_RS09420	COG3706	GGDEF domain
AOY38_RS09425	COG0784	Response regulator, receiver
AOY38_RS09435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOY38_RS09435	COG0072	phenylalanine-tRNA ligase activity
AOY38_RS09440	COG0515	serine threonine protein kinase
AOY38_RS09440	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS09445	COG2197	response regulator
AOY38_RS09450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AOY38_RS09465	COG0157	Belongs to the NadC ModD family
AOY38_RS09480	COG2082	Precorrin-8x methylmutase
AOY38_RS09485	COG0612	Peptidase, M16
AOY38_RS09490	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AOY38_RS09500	COG0656	L-ascorbic acid biosynthetic process
AOY38_RS09505	COG3588	fructose-bisphosphate aldolase
AOY38_RS09515	COG0798	PFAM Bile acid sodium symporter
AOY38_RS09520	COG0431	NADPH-dependent FMN reductase
AOY38_RS09525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOY38_RS09545	COG0488	(ABC) transporter
AOY38_RS09555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AOY38_RS09575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AOY38_RS09580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AOY38_RS09585	COG0561	phosphatase activity
AOY38_RS09590	COG1366	Belongs to the anti-sigma-factor antagonist family
AOY38_RS09595	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AOY38_RS09600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOY38_RS09610	COG0215	cysteine-tRNA ligase activity
AOY38_RS09615	COG0424	maF-like protein
AOY38_RS09630	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AOY38_RS09635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOY38_RS09640	COG0463	Glycosyl transferase, family 2
AOY38_RS09645	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOY38_RS09660	COG1472	Belongs to the glycosyl hydrolase 3 family
AOY38_RS09665	COG2816	NAD+ diphosphatase activity
AOY38_RS09670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOY38_RS09675	COG1280	lysine exporter protein (LysE YggA)
AOY38_RS09690	COG0564	pseudouridine synthase activity
AOY38_RS09700	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS09740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AOY38_RS09755	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS09765	COG0500	methyltransferase
AOY38_RS09770	COG0542	response to heat
AOY38_RS09780	COG0572	uridine kinase
AOY38_RS09785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOY38_RS09790	COG0561	phosphatase activity
AOY38_RS09805	COG0571	ribonuclease III activity
AOY38_RS09810	COG0390	transport system, permease component
AOY38_RS09815	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AOY38_RS09820	COG2161	toxin-antitoxin pair type II binding
AOY38_RS09835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOY38_RS09840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOY38_RS09840	COG0426	domain, Protein
AOY38_RS09845	COG0497	DNA recombination
AOY38_RS09855	COG3751	2OG-Fe(II) oxygenase superfamily
AOY38_RS09885	COG2161	toxin-antitoxin pair type II binding
AOY38_RS09910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOY38_RS09915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOY38_RS09930	COG1446	asparaginase
AOY38_RS09935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOY38_RS09945	COG0832	Belongs to the urease beta subunit family
AOY38_RS09955	COG2226	methyltransferase
AOY38_RS09970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOY38_RS09980	COG0025	NhaP-type Na H and K H
AOY38_RS09990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOY38_RS10000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOY38_RS10040	COG3239	Fatty acid desaturase
AOY38_RS10050	COG1950	PFAM Membrane protein of
AOY38_RS10065	COG1253	flavin adenine dinucleotide binding
AOY38_RS10070	COG0228	four-way junction DNA binding
AOY38_RS10090	COG2010	Cytochrome c
AOY38_RS10105	COG0802	atpase or kinase
AOY38_RS10110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOY38_RS10110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AOY38_RS10135	COG0126	phosphoglycerate kinase activity
AOY38_RS10140	COG0583	DNA-binding transcription factor activity
AOY38_RS10145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOY38_RS10180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOY38_RS10195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AOY38_RS10200	COG0347	Belongs to the P(II) protein family
AOY38_RS10215	COG0135	phosphoribosylanthranilate isomerase activity
AOY38_RS10220	COG0697	spore germination
AOY38_RS10235	COG0418	dihydroorotase activity
AOY38_RS10240	COG2226	methyltransferase
AOY38_RS10255	COG1672	PFAM Archaeal ATPase
AOY38_RS10255	COG2319	Wd-40 repeat
AOY38_RS10305	COG0515	serine threonine protein kinase
AOY38_RS10305	COG2815	serine threonine protein kinase
AOY38_RS10330	COG0233	cytoplasmic translational termination
AOY38_RS10335	COG0528	UMP kinase activity
AOY38_RS10340	COG1598	PFAM Uncharacterised protein family UPF0150
AOY38_RS10350	COG0542	response to heat
AOY38_RS10375	COG1459	type II secretion system
AOY38_RS10380	COG0740	serine-type endopeptidase activity
AOY38_RS10385	COG0740	serine-type endopeptidase activity
AOY38_RS10390	COG0006	proline dipeptidase activity
AOY38_RS10395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AOY38_RS10420	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
AOY38_RS10430	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AOY38_RS10435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOY38_RS10470	COG2165	general secretion pathway protein
AOY38_RS10475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOY38_RS10515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOY38_RS10535	COG0105	UTP biosynthetic process
AOY38_RS10565	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AOY38_RS10570	COG2937	Belongs to the GPAT DAPAT family
AOY38_RS10580	COG0501	Belongs to the peptidase M48B family
AOY38_RS10600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AOY38_RS10610	COG0463	Glycosyl transferase, family 2
AOY38_RS10620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOY38_RS10635	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOY38_RS10645	COG2217	Heavy metal translocating P-type atpase
AOY38_RS10655	COG0217	transcriptional regulatory protein
AOY38_RS10660	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AOY38_RS10665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOY38_RS10670	COG0739	heme binding
AOY38_RS10675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOY38_RS10680	COG0321	lipoyl(octanoyl) transferase activity
AOY38_RS10695	COG0297	glycogen (starch) synthase activity
AOY38_RS10710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOY38_RS10715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOY38_RS10740	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS10755	COG1178	ABC-type Fe3 transport system permease component
AOY38_RS10760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOY38_RS10785	COG2197	response regulator
AOY38_RS10790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS10795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS10820	COG0237	dephospho-CoA kinase activity
AOY38_RS10820	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOY38_RS10855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS10865	COG0517	IMP dehydrogenase activity
AOY38_RS10865	COG0516	GMP reductase activity
AOY38_RS10875	COG1937	Protein conserved in bacteria
AOY38_RS10890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AOY38_RS10910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOY38_RS10915	COG0443	Heat shock 70 kDa protein
AOY38_RS10935	COG1587	Uroporphyrinogen-III synthase
AOY38_RS10940	COG2319	Wd-40 repeat
AOY38_RS10960	COG3385	transposase activity
AOY38_RS10970	COG1381	Involved in DNA repair and RecF pathway recombination
AOY38_RS10985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOY38_RS11005	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AOY38_RS11010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOY38_RS11015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOY38_RS11020	COG5001	Diguanylate cyclase
AOY38_RS11030	COG1187	pseudouridine synthase activity
AOY38_RS11035	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AOY38_RS11065	COG1012	belongs to the aldehyde dehydrogenase family
AOY38_RS11070	COG5002	protein histidine kinase activity
AOY38_RS11075	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AOY38_RS11080	COG2308	Evidence 4 Homologs of previously reported genes of
AOY38_RS11110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AOY38_RS11120	COG0346	lactoylglutathione lyase activity
AOY38_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS11135	COG0742	ribosomal rna small subunit methyltransferase
AOY38_RS11140	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS11145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOY38_RS11165	COG1104	cysteine desulfurase activity
AOY38_RS11170	COG1040	competence protein
AOY38_RS11175	COG1376	ErfK ybiS ycfS ynhG family protein
AOY38_RS11190	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOY38_RS11200	COG3659	wide pore channel activity
AOY38_RS11205	COG0477	Major facilitator Superfamily
AOY38_RS11210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOY38_RS11215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOY38_RS11220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOY38_RS11225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AOY38_RS11230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AOY38_RS11235	COG2003	Belongs to the UPF0758 family
AOY38_RS11240	COG1054	Belongs to the UPF0176 family
AOY38_RS11250	COG0411	ABC transporter
AOY38_RS11270	COG1131	(ABC) transporter
AOY38_RS11280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOY38_RS11290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AOY38_RS11300	COG0450	alkyl hydroperoxide reductase
AOY38_RS11305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AOY38_RS11315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AOY38_RS11325	COG1231	oxidoreductase activity
AOY38_RS11330	COG2205	protein histidine kinase activity
AOY38_RS11340	COG0149	triose-phosphate isomerase activity
AOY38_RS11345	COG0628	permease
AOY38_RS11360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOY38_RS11365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOY38_RS11380	COG0571	ribonuclease III activity
AOY38_RS11385	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AOY38_RS11410	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOY38_RS11430	COG3385	transposase activity
AOY38_RS11450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOY38_RS11475	COG1748	Saccharopine dehydrogenase
AOY38_RS11485	COG0601	transmembrane transport
AOY38_RS11490	COG0124	histidyl-tRNA synthetase
AOY38_RS11535	COG0542	response to heat
AOY38_RS11540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOY38_RS11545	COG0191	fructose-bisphosphate aldolase activity
AOY38_RS11550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AOY38_RS11570	COG0793	Belongs to the peptidase S41A family
AOY38_RS11575	COG1850	ribulose-bisphosphate carboxylase activity
AOY38_RS11585	COG4451	ribulose bisphosphate carboxylase, small
AOY38_RS11595	COG1285	pathogenesis
AOY38_RS11605	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOY38_RS11610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOY38_RS11620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOY38_RS11625	COG0114	fumarate hydratase activity
AOY38_RS11650	COG0436	Aminotransferase
AOY38_RS11655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY38_RS11660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOY38_RS11665	COG0616	signal peptide processing
AOY38_RS11670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOY38_RS11680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOY38_RS11680	COG0519	Catalyzes the synthesis of GMP from XMP
AOY38_RS11690	COG1968	undecaprenyl-diphosphatase activity
AOY38_RS11710	COG5322	oxidoreductase activity
AOY38_RS11715	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AOY38_RS11725	COG0751	glycine-tRNA ligase activity
AOY38_RS11740	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AOY38_RS11745	COG5002	protein histidine kinase activity
AOY38_RS11750	COG0445	tRNA wobble uridine modification
AOY38_RS11770	COG3794	PFAM blue (type 1) copper domain protein
AOY38_RS11785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY38_RS11790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOY38_RS11795	COG0805	protein transport
AOY38_RS11800	COG2084	Dehydrogenase
AOY38_RS11815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOY38_RS11825	COG0586	Pfam SNARE associated Golgi protein
AOY38_RS11830	COG3118	belongs to the thioredoxin family
AOY38_RS11835	COG3751	2OG-Fe(II) oxygenase superfamily
AOY38_RS11840	COG0459	protein refolding
AOY38_RS11845	COG1131	(ABC) transporter
AOY38_RS11870	COG4399	Belongs to the UPF0754 family
AOY38_RS11875	COG0824	Thioesterase
AOY38_RS11880	COG4948	Mandelate Racemase Muconate Lactonizing
AOY38_RS11885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOY38_RS11890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOY38_RS11895	COG0511	ligase activity, forming carbon-carbon bonds
AOY38_RS11900	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
AOY38_RS11925	COG0277	FAD linked oxidase domain protein
AOY38_RS11945	COG0436	Aminotransferase
AOY38_RS11950	COG0372	Belongs to the citrate synthase family
AOY38_RS11955	COG2062	phosphohistidine phosphatase, SixA
AOY38_RS11960	COG0596	Alpha beta hydrolase
AOY38_RS11975	COG1234	tRNA 3'-trailer cleavage
AOY38_RS11990	COG0788	formyltetrahydrofolate deformylase activity
AOY38_RS12010	COG0625	glutathione transferase activity
AOY38_RS12020	COG0440	acetolactate synthase activity
AOY38_RS12030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AOY38_RS12035	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOY38_RS12045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOY38_RS12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOY38_RS12060	COG0628	permease
AOY38_RS12095	COG0628	permease
AOY38_RS12100	COG0443	Heat shock 70 kDa protein
AOY38_RS12105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOY38_RS12110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOY38_RS12115	COG0116	Belongs to the methyltransferase superfamily
AOY38_RS12125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOY38_RS12125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOY38_RS12130	COG0612	Peptidase, M16
AOY38_RS12135	COG0489	protein tyrosine kinase activity
AOY38_RS12140	COG0439	Biotin carboxylase
AOY38_RS12145	COG3224	Antibiotic biosynthesis monooxygenase
AOY38_RS12150	COG0590	tRNA wobble adenosine to inosine editing
AOY38_RS12155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOY38_RS12170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AOY38_RS12185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOY38_RS12190	COG4251	negative regulation of phosphorylation
AOY38_RS12195	COG0784	Response regulator, receiver
AOY38_RS12200	COG0556	nucleotide-excision repair
AOY38_RS12225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOY38_RS12230	COG2890	protein-(glutamine-N5) methyltransferase activity
AOY38_RS12235	COG0525	valine-tRNA ligase activity
AOY38_RS12240	COG5002	protein histidine kinase activity
AOY38_RS12250	COG0728	peptidoglycan biosynthetic process
AOY38_RS12265	COG0318	PFAM AMP-dependent synthetase and ligase
AOY38_RS12280	COG0460	homoserine dehydrogenase
AOY38_RS12285	COG2091	lysine biosynthetic process via aminoadipic acid
AOY38_RS12295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AOY38_RS12315	COG0475	glutathione-regulated potassium exporter activity
AOY38_RS12330	COG4232	protein-disulfide reductase activity
AOY38_RS12340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOY38_RS12345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOY38_RS12350	COG0581	inorganic phosphate transmembrane transporter activity
AOY38_RS12365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOY38_RS12380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AOY38_RS12385	COG1842	Phage shock protein A
AOY38_RS12400	COG0653	protein targeting
AOY38_RS12405	COG2119	membrane
AOY38_RS12415	COG2255	four-way junction helicase activity
AOY38_RS12420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOY38_RS12420	COG2022	thiamine diphosphate biosynthetic process
AOY38_RS12430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AOY38_RS12440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AOY38_RS12450	COG0752	glycyl-tRNA synthetase alpha subunit
AOY38_RS12455	COG0668	transmembrane transport
AOY38_RS12460	COG5002	protein histidine kinase activity
AOY38_RS12475	COG2211	Major facilitator Superfamily
AOY38_RS12490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOY38_RS12495	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOY38_RS12525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOY38_RS12535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOY38_RS12545	COG0745	RESPONSE REGULATOR receiver
AOY38_RS12550	COG0406	alpha-ribazole phosphatase activity
AOY38_RS12560	COG0589	response to stress
AOY38_RS12560	COG0475	glutathione-regulated potassium exporter activity
AOY38_RS12575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOY38_RS12585	COG1122	ATPase activity
AOY38_RS12595	COG0310	cobalt ion transport
AOY38_RS12620	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS12625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOY38_RS12640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOY38_RS12645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOY38_RS12655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOY38_RS12665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AOY38_RS12680	COG1598	PFAM Uncharacterised protein family UPF0150
AOY38_RS12690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOY38_RS12700	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AOY38_RS12705	COG0302	gtp cyclohydrolase
AOY38_RS12710	COG1546	Belongs to the CinA family
AOY38_RS12710	COG1058	Belongs to the CinA family
AOY38_RS12715	COG0792	nuclease activity
AOY38_RS12725	COG2247	cell wall binding repeat
AOY38_RS12725	COG2385	sporulation resulting in formation of a cellular spore
AOY38_RS12730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOY38_RS12740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOY38_RS12765	COG0121	glutamine amidotransferase
AOY38_RS12770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOY38_RS12775	COG2048	Heterodisulfide reductase, subunit B
AOY38_RS12780	COG0762	integral membrane protein
AOY38_RS12790	COG4178	(ABC) transporter
AOY38_RS12815	COG0824	Thioesterase
AOY38_RS12820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOY38_RS12845	COG2205	protein histidine kinase activity
AOY38_RS12845	COG2202	Pas domain
AOY38_RS12860	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOY38_RS12865	COG1410	methionine synthase
AOY38_RS12865	COG0646	methionine synthase
AOY38_RS12895	COG0646	methionine synthase
AOY38_RS12895	COG1410	methionine synthase
AOY38_RS12910	COG1309	transcriptional regulator
AOY38_RS12915	COG0534	Mate efflux family protein
AOY38_RS12930	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOY38_RS12935	COG0303	'Molybdopterin
AOY38_RS12940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOY38_RS12945	COG0746	molybdenum cofactor guanylyltransferase activity
AOY38_RS12945	COG0315	cyclic pyranopterin monophosphate synthase activity
AOY38_RS12955	COG0314	molybdopterin synthase activity
AOY38_RS12965	COG0606	chelatase, subunit chli
AOY38_RS12970	COG1032	radical SAM domain protein
AOY38_RS13010	COG0156	8-amino-7-oxononanoate synthase activity
AOY38_RS13015	COG0024	Methionine aminopeptidase
AOY38_RS13025	COG0494	nUDIX hydrolase
AOY38_RS13030	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AOY38_RS13035	COG0039	L-malate dehydrogenase activity
AOY38_RS13050	COG0193	aminoacyl-tRNA hydrolase activity
AOY38_RS13080	COG0024	Methionine aminopeptidase
AOY38_RS13085	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
AOY38_RS13100	COG4243	Vitamin k epoxide reductase
AOY38_RS13105	COG0426	domain, Protein
AOY38_RS13105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOY38_RS13110	COG0613	PHP domain protein
AOY38_RS13115	COG2251	uridine kinase activity
AOY38_RS13120	COG3063	Type IV pilus biogenesis stability protein PilW
AOY38_RS13125	COG0023	Translation Initiation Factor
AOY38_RS13165	COG2954	triphosphatase activity
AOY38_RS13170	COG2124	cytochrome p450
AOY38_RS13180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOY38_RS13195	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AOY38_RS13220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOY38_RS13230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOY38_RS13235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AOY38_RS13240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOY38_RS13250	COG3706	GGDEF domain
AOY38_RS13250	COG2203	Gaf domain
AOY38_RS13250	COG4251	negative regulation of phosphorylation
AOY38_RS13250	COG5001	Diguanylate cyclase
AOY38_RS13255	COG0659	secondary active sulfate transmembrane transporter activity
AOY38_RS13260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOY38_RS13275	COG1372	Participates in initiation and elongation during chromosome replication
AOY38_RS13275	COG0305	Participates in initiation and elongation during chromosome replication
AOY38_RS13280	COG0714	Associated with various cellular activities
AOY38_RS13295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOY38_RS13300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AOY38_RS13305	COG2226	methyltransferase
AOY38_RS13310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOY38_RS13315	COG0154	amidase activity
AOY38_RS13330	COG5001	Diguanylate cyclase
AOY38_RS13330	COG4251	negative regulation of phosphorylation
AOY38_RS13330	COG3706	GGDEF domain
AOY38_RS13330	COG2203	Gaf domain
AOY38_RS13335	COG0617	tRNA 3'-terminal CCA addition
AOY38_RS13345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOY38_RS13360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOY38_RS13370	COG1959	2 iron, 2 sulfur cluster binding
AOY38_RS13375	COG4251	negative regulation of phosphorylation
AOY38_RS13375	COG5001	Diguanylate cyclase
AOY38_RS13375	COG3706	GGDEF domain
AOY38_RS13375	COG2203	Gaf domain
AOY38_RS13380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AOY38_RS13390	COG0357	Ribosomal RNA small subunit methyltransferase G
AOY38_RS13405	COG0719	Fe-S assembly protein
AOY38_RS13410	COG0396	ATPase activity
AOY38_RS13415	COG0719	Fe-S assembly protein
AOY38_RS13420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOY38_RS13425	COG0003	Pfam Anion-transporting ATPase
AOY38_RS13440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AOY38_RS13445	COG0720	synthase
AOY38_RS13460	COG0328	RNA-DNA hybrid ribonuclease activity
AOY38_RS13465	COG0745	RESPONSE REGULATOR receiver
AOY38_RS13470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOY38_RS13475	COG0513	Belongs to the DEAD box helicase family
AOY38_RS13480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AOY38_RS13485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOY38_RS13490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOY38_RS13495	COG0443	Heat shock 70 kDa protein
AOY38_RS13505	COG2226	methyltransferase
AOY38_RS13510	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOY38_RS13515	COG1012	belongs to the aldehyde dehydrogenase family
AOY38_RS13520	COG1216	Glycosyl transferase, family 2
AOY38_RS13525	COG0484	heat shock protein binding
AOY38_RS13535	COG0659	secondary active sulfate transmembrane transporter activity
AOY38_RS13545	COG1131	(ABC) transporter
AOY38_RS13550	COG0131	Imidazoleglycerol-phosphate dehydratase
AOY38_RS13560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY38_RS13565	COG4251	negative regulation of phosphorylation
AOY38_RS13570	COG2197	response regulator
AOY38_RS13585	COG0515	serine threonine protein kinase
AOY38_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
AOY38_RS13610	COG0436	Aminotransferase
AOY38_RS13615	COG0586	Pfam SNARE associated Golgi protein
AOY38_RS13620	COG3264	Mechanosensitive ion channel
AOY38_RS13620	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOY38_RS13635	COG0848	biopolymer transport protein
AOY38_RS13640	COG0848	biopolymer transport protein
AOY38_RS13645	COG0811	peptide transport
AOY38_RS13650	COG1840	ABC-type Fe3 transport system, periplasmic component
AOY38_RS13660	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS13665	COG2205	protein histidine kinase activity
AOY38_RS13675	COG0456	acetyltransferase
AOY38_RS13680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOY38_RS13685	COG0047	phosphoribosylformylglycinamidine synthase activity
AOY38_RS13710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOY38_RS13715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AOY38_RS13720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AOY38_RS13725	COG0628	permease
AOY38_RS13740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY38_RS13745	COG0837	glucose binding
AOY38_RS13750	COG1132	(ABC) transporter
AOY38_RS13770	COG0668	transmembrane transport
AOY38_RS13775	COG1492	cobalamin metabolic process
AOY38_RS13795	COG0469	pyruvate kinase activity
AOY38_RS13800	COG2081	HI0933 family
AOY38_RS13805	COG3118	belongs to the thioredoxin family
AOY38_RS13820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AOY38_RS13835	COG0457	Tetratricopeptide repeat
AOY38_RS13835	COG0463	Glycosyl transferase, family 2
AOY38_RS13850	COG0004	ammonium transporteR
AOY38_RS13855	COG0800	Aldolase
AOY38_RS13865	COG1480	7TM receptor with intracellular HD hydrolase
AOY38_RS13870	COG2304	oxidoreductase activity
AOY38_RS13880	COG1192	Involved in chromosome partitioning
AOY38_RS13895	COG1473	amidohydrolase
AOY38_RS13905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOY38_RS13930	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOY38_RS13935	COG0784	Response regulator, receiver
AOY38_RS13935	COG2205	protein histidine kinase activity
AOY38_RS13940	COG1192	Involved in chromosome partitioning
AOY38_RS13960	COG0745	RESPONSE REGULATOR receiver
AOY38_RS13975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AOY38_RS13985	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AOY38_RS13995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOY38_RS14010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AOY38_RS14015	COG2894	cell division
AOY38_RS14020	COG0850	regulation of cytokinetic process
AOY38_RS14025	COG1716	ATPase activity
AOY38_RS14040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOY38_RS14040	COG0574	Belongs to the PEP-utilizing enzyme family
AOY38_RS14060	COG0398	Pfam SNARE associated Golgi protein
AOY38_RS14065	COG0737	Belongs to the 5'-nucleotidase family
AOY38_RS14070	COG0454	-acetyltransferase
AOY38_RS14085	COG1032	radical SAM domain protein
AOY38_RS14105	COG4585	Histidine kinase
AOY38_RS14110	COG2197	response regulator
AOY38_RS14115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOY38_RS14115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOY38_RS14120	COG2267	carboxylic ester hydrolase activity
AOY38_RS14125	COG4221	oxidoreductase activity
AOY38_RS14160	COG0024	Methionine aminopeptidase
AOY38_RS14180	COG1056	cytidyltransferase-related domain
AOY38_RS14180	COG1051	belongs to the nudix hydrolase family
AOY38_RS14195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOY38_RS14200	COG5002	protein histidine kinase activity
AOY38_RS14225	COG2814	Major facilitator Superfamily
AOY38_RS14235	COG2217	Heavy metal translocating P-type atpase
AOY38_RS14240	COG1742	UPF0060 membrane protein
AOY38_RS14245	COG0640	Transcriptional regulator
AOY38_RS14250	COG2217	Heavy metal translocating P-type atpase
AOY38_RS14255	COG5002	protein histidine kinase activity
AOY38_RS14260	COG0745	RESPONSE REGULATOR receiver
AOY38_RS14280	COG2144	transferase activity, transferring acyl groups
AOY38_RS14305	COG2072	flavoprotein involved in K transport
AOY38_RS14310	COG2197	response regulator
AOY38_RS14325	COG5001	Diguanylate cyclase
AOY38_RS14325	COG4251	negative regulation of phosphorylation
AOY38_RS14325	COG3706	GGDEF domain
AOY38_RS14325	COG2203	Gaf domain
AOY38_RS14330	COG1716	ATPase activity
AOY38_RS14330	COG1131	(ABC) transporter
AOY38_RS14330	COG0842	Transport permease protein
AOY38_RS14340	COG4991	sh3 domain protein
AOY38_RS14340	COG0515	serine threonine protein kinase
AOY38_RS14340	COG3064	Membrane
AOY38_RS14355	COG2954	triphosphatase activity
AOY38_RS14370	COG0789	Transcriptional regulator
AOY38_RS14415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOY38_RS14420	COG0598	Magnesium transport protein CorA
AOY38_RS14430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOY38_RS14430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOY38_RS14465	COG0251	oxidation-reduction process
AOY38_RS14470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOY38_RS14475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOY38_RS14480	COG0392	lysyltransferase activity
AOY38_RS14500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOY38_RS14510	COG0343	queuine tRNA-ribosyltransferase activity
AOY38_RS14525	COG2886	Uncharacterised protein family (UPF0175)
AOY38_RS14530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOY38_RS14535	COG0668	transmembrane transport
AOY38_RS14540	COG0205	6-phosphofructokinase activity
AOY38_RS14560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOY38_RS14560	COG1013	pyruvate-flavodoxin oxidoreductase activity
AOY38_RS14560	COG0674	pyruvate-flavodoxin oxidoreductase activity
AOY38_RS14560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AOY38_RS14570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOY38_RS14575	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOY38_RS14600	COG0438	transferase activity, transferring glycosyl groups
AOY38_RS14615	COG0784	Response regulator, receiver
AOY38_RS14615	COG0643	Histidine kinase
AOY38_RS14615	COG2198	Histidine kinase
AOY38_RS14620	COG0840	transmembrane signaling receptor activity
AOY38_RS14625	COG2203	Gaf domain
AOY38_RS14625	COG0840	transmembrane signaling receptor activity
AOY38_RS14640	COG0784	Response regulator, receiver
AOY38_RS14650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOY38_RS14655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOY38_RS14660	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AOY38_RS14665	COG1597	lipid kinase activity
AOY38_RS14665	COG1803	Methylglyoxal synthase
AOY38_RS14670	COG0436	Aminotransferase
AOY38_RS14695	COG0857	belongs to the CobB CobQ family
AOY38_RS14700	COG0583	DNA-binding transcription factor activity
AOY38_RS14705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY38_RS14710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOY38_RS14715	COG3659	wide pore channel activity
AOY38_RS14720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOY38_RS14720	COG1116	anion transmembrane transporter activity
AOY38_RS14725	COG1116	anion transmembrane transporter activity
AOY38_RS14730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS14735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOY38_RS14745	COG0724	RNA recognition motif
AOY38_RS14750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOY38_RS14755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AOY38_RS14760	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOY38_RS14765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOY38_RS14770	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AOY38_RS14775	COG1653	transport
AOY38_RS14780	COG1175	transmembrane transport
AOY38_RS14785	COG0395	ABC-type sugar transport system, permease component
AOY38_RS14795	COG2205	protein histidine kinase activity
AOY38_RS14800	COG0741	lytic transglycosylase activity
AOY38_RS14810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOY38_RS14825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOY38_RS14830	COG0598	Magnesium transport protein CorA
AOY38_RS14835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOY38_RS14840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AOY38_RS14845	COG0019	diaminopimelate decarboxylase activity
AOY38_RS14850	COG1160	GTP binding
AOY38_RS14855	COG0018	arginyl-trna synthetase
AOY38_RS14860	COG0463	Glycosyl transferase, family 2
AOY38_RS14870	COG0740	serine-type endopeptidase activity
AOY38_RS14875	COG0133	tryptophan synthase activity
AOY38_RS14885	COG1136	(ABC) transporter
AOY38_RS14890	COG2314	TM2 domain
AOY38_RS14910	COG0017	Asparaginyl-tRNA synthetase
AOY38_RS14930	COG0569	domain protein
AOY38_RS14935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOY38_RS14940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOY38_RS14945	COG0629	single-stranded DNA binding
AOY38_RS14955	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOY38_RS14965	COG1192	Involved in chromosome partitioning
AOY38_RS14975	COG2119	membrane
AOY38_RS14980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOY38_RS14985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AOY38_RS14995	COG1162	GTPase activity
AOY38_RS15005	COG0484	heat shock protein binding
AOY38_RS15010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AOY38_RS15015	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOY38_RS15025	COG0134	indole-3-glycerol-phosphate synthase activity
AOY38_RS15030	COG0004	ammonium transporteR
AOY38_RS15035	COG0569	domain protein
AOY38_RS15040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOY38_RS15045	COG0740	serine-type endopeptidase activity
AOY38_RS15050	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOY38_RS15055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOY38_RS15060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOY38_RS15065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOY38_RS15075	COG0237	dephospho-CoA kinase activity
AOY38_RS15090	COG0517	IMP dehydrogenase activity
AOY38_RS15090	COG1994	Peptidase M50
AOY38_RS15095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOY38_RS15115	COG0525	valine-tRNA ligase activity
AOY38_RS15120	COG0713	ATP synthesis coupled electron transport
AOY38_RS15125	COG0839	Belongs to the complex I subunit 6 family
AOY38_RS15130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOY38_RS15135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AOY38_RS15140	COG0167	dihydroorotate dehydrogenase activity
AOY38_RS15145	COG2166	iron-sulfur cluster assembly
AOY38_RS15150	COG1070	Carbohydrate kinase
AOY38_RS15175	COG0308	aminopeptidase N
AOY38_RS15180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOY38_RS15185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOY38_RS15190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOY38_RS15200	COG2193	ferroxidase activity
AOY38_RS15210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOY38_RS15220	COG1834	amidinotransferase
AOY38_RS15225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOY38_RS15255	COG0745	RESPONSE REGULATOR receiver
AOY38_RS15260	COG0483	inositol monophosphate 1-phosphatase activity
AOY38_RS15275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOY38_RS15280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOY38_RS15285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOY38_RS15290	COG4208	sulfate ABC transporter
AOY38_RS15295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOY38_RS15300	COG2165	general secretion pathway protein
AOY38_RS15315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOY38_RS15330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOY38_RS15335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOY38_RS15340	COG0731	radical SAM domain protein
AOY38_RS15350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AOY38_RS15355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOY38_RS15365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AOY38_RS15370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOY38_RS15385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOY38_RS15440	COG0339	signal peptide processing
AOY38_RS15445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOY38_RS15470	COG1166	arginine decarboxylase activity
AOY38_RS15480	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOY38_RS15500	COG1049	propionate catabolic process, 2-methylcitrate cycle
AOY38_RS15520	COG0070	glutamate synthase
AOY38_RS15520	COG0069	glutamate synthase activity
AOY38_RS15520	COG0067	glutamate synthase
AOY38_RS15525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOY38_RS15530	COG0505	Belongs to the CarA family
AOY38_RS15540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOY38_RS15545	COG0579	oxidoreductase
AOY38_RS15555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AOY38_RS15560	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AOY38_RS15565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOY38_RS15570	COG3001	Fructosamine kinase
AOY38_RS15580	COG1191	sigma factor activity
AOY38_RS15585	COG0316	Belongs to the HesB IscA family
AOY38_RS15590	COG0463	Glycosyl transferase, family 2
AOY38_RS15595	COG2319	Wd-40 repeat
AOY38_RS15610	COG1691	(AIR) carboxylase
AOY38_RS15615	COG0739	heme binding
AOY38_RS15635	COG1496	oxidoreductase activity
AOY38_RS15640	COG2052	Domain of unknown function (DUF370)
AOY38_RS15645	COG3264	Mechanosensitive ion channel
AOY38_RS15645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOY38_RS15680	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOY38_RS15695	COG0363	glucosamine-6-phosphate deaminase activity
AOY38_RS15715	COG4251	negative regulation of phosphorylation
AOY38_RS15715	COG2203	Gaf domain
AOY38_RS15715	COG3706	GGDEF domain
AOY38_RS15715	COG5001	Diguanylate cyclase
AOY38_RS15725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOY38_RS15745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOY38_RS15750	COG3300	MHYT domain
AOY38_RS15750	COG5001	Diguanylate cyclase
AOY38_RS15760	COG3842	ATPase activity
AOY38_RS15770	COG1543	Belongs to the glycosyl hydrolase 57 family
AOY38_RS15780	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AOY38_RS15785	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AOY38_RS15795	COG0457	Tetratricopeptide repeat
AOY38_RS15800	COG0148	phosphopyruvate hydratase activity
AOY38_RS15810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOY38_RS15825	COG0825	malonyl-CoA metabolic process
AOY38_RS15850	COG1598	PFAM Uncharacterised protein family UPF0150
AOY38_RS15880	COG4251	negative regulation of phosphorylation
AOY38_RS15885	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AOY38_RS15910	COG2994	toxin metabolic process
AOY38_RS15930	COG0170	dolichyl monophosphate biosynthetic process
AOY38_RS15935	COG1473	amidohydrolase
AOY38_RS15940	COG3659	wide pore channel activity
AOY38_RS15960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOY38_RS15965	COG5001	Diguanylate cyclase
AOY38_RS15965	COG4251	negative regulation of phosphorylation
AOY38_RS15965	COG3706	GGDEF domain
AOY38_RS15965	COG2203	Gaf domain
AOY38_RS15990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOY38_RS16020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOY38_RS16035	COG2197	response regulator
AOY38_RS16080	COG2153	protein acetylation
AOY38_RS16130	COG4581	dead DEAH box helicase
AOY38_RS16140	COG0322	excinuclease ABC activity
AOY38_RS16145	COG0129	dihydroxy-acid dehydratase activity
AOY38_RS16150	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AOY38_RS16180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOY38_RS16185	COG0546	phosphoglycolate phosphatase activity
AOY38_RS16215	COG0326	Molecular chaperone. Has ATPase activity
AOY38_RS16220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOY38_RS16235	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOY38_RS16240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AOY38_RS16250	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOY38_RS16280	COG0723	plastoquinol--plastocyanin reductase activity
AOY38_RS16295	COG1842	Phage shock protein A
AOY38_RS16315	COG1064	alcohol dehydrogenase
AOY38_RS16320	COG0137	argininosuccinate synthase activity
AOY38_RS16335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOY38_RS16340	COG1357	PFAM Pentapeptide repeats (8 copies)
AOY38_RS16360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOY38_RS16375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOY38_RS16380	COG0549	Belongs to the carbamate kinase family
AOY38_RS16400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOY38_RS16405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOY38_RS16410	COG1136	(ABC) transporter
AOY38_RS16410	COG0577	efflux transmembrane transporter activity
AOY38_RS16415	COG0735	belongs to the Fur family
AOY38_RS16425	COG0138	bifunctional purine biosynthesis protein purh
AOY38_RS16445	COG0515	serine threonine protein kinase
AOY38_RS16470	COG0587	DNA-directed DNA polymerase activity
AOY38_RS16475	COG0481	GTPase activity
AOY38_RS16480	COG0435	Glutathione S-transferase
AOY38_RS16495	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOY38_RS16495	COG0140	phosphoribosyl-ATP diphosphatase activity
AOY38_RS16500	COG0523	cobalamin synthesis protein