locus-tag	class	description
SGLY_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SGLY_RS00010	COG0592	DNA-directed DNA polymerase activity
SGLY_RS00025	COG0187	DNA topoisomerase II activity
SGLY_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SGLY_RS00035	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SGLY_RS00040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SGLY_RS00060	COG0590	tRNA wobble adenosine to inosine editing
SGLY_RS00075	COG1373	ATPase (AAA superfamily
SGLY_RS00100	COG0582	viral genome integration into host DNA
SGLY_RS00110	COG2337	Toxic component of a toxin-antitoxin (TA) module
SGLY_RS00120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGLY_RS00130	COG2217	Heavy metal translocating P-type atpase
SGLY_RS00160	COG0798	PFAM Bile acid sodium symporter
SGLY_RS00215	COG0739	heme binding
SGLY_RS00215	COG0741	lytic transglycosylase activity
SGLY_RS00215	COG1196	nuclear chromosome segregation
SGLY_RS00265	COG0582	viral genome integration into host DNA
SGLY_RS00345	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SGLY_RS00365	COG2088	sporulation resulting in formation of a cellular spore
SGLY_RS00420	COG0582	viral genome integration into host DNA
SGLY_RS00430	COG3177	Filamentation induced by cAMP protein fic
SGLY_RS00435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SGLY_RS00440	COG0210	DNA helicase
SGLY_RS00490	COG3177	Filamentation induced by cAMP protein fic
SGLY_RS00500	COG1595	DNA-templated transcription, initiation
SGLY_RS00520	COG1191	sigma factor activity
SGLY_RS00555	COG1131	(ABC) transporter
SGLY_RS00585	COG1918	ferrous iron import across plasma membrane
SGLY_RS00610	COG0840	transmembrane signaling receptor activity
SGLY_RS00620	COG0651	ATP synthesis coupled electron transport
SGLY_RS00625	COG0650	Formate hydrogenlyase subunit 4
SGLY_RS00635	COG0651	ATP synthesis coupled electron transport
SGLY_RS00640	COG3261	NADH dehydrogenase
SGLY_RS00640	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SGLY_RS00645	COG3260	NADH ubiquinone oxidoreductase 20
SGLY_RS00655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGLY_RS00660	COG0573	inorganic phosphate transmembrane transporter activity
SGLY_RS00665	COG0581	inorganic phosphate transmembrane transporter activity
SGLY_RS00670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SGLY_RS00675	COG0704	Plays a role in the regulation of phosphate uptake
SGLY_RS00680	COG0745	RESPONSE REGULATOR receiver
SGLY_RS00690	COG3300	MHYT domain
SGLY_RS00690	COG5001	Diguanylate cyclase
SGLY_RS00695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SGLY_RS00705	COG0741	lytic transglycosylase activity
SGLY_RS00715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SGLY_RS00720	COG1131	(ABC) transporter
SGLY_RS00725	COG1131	(ABC) transporter
SGLY_RS00730	COG0842	Transport permease protein
SGLY_RS00745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SGLY_RS00750	COG0248	Ppx GppA phosphatase
SGLY_RS00760	COG0667	Aldo Keto reductase
SGLY_RS00770	COG1233	COG1233 Phytoene dehydrogenase and related
SGLY_RS00785	COG0701	Predicted permease
SGLY_RS00790	COG0523	cobalamin synthesis protein
SGLY_RS00795	COG0735	belongs to the Fur family
SGLY_RS00800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGLY_RS00805	COG1121	(ABC) transporter
SGLY_RS00810	COG0803	Belongs to the bacterial solute-binding protein 9 family
SGLY_RS00815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SGLY_RS00820	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SGLY_RS00835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SGLY_RS00835	COG1013	pyruvate-flavodoxin oxidoreductase activity
SGLY_RS00835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SGLY_RS00835	COG0674	pyruvate-flavodoxin oxidoreductase activity
SGLY_RS00850	COG1982	Orn Lys Arg decarboxylase major
SGLY_RS00855	COG0470	DNA polymerase III
SGLY_RS00860	COG1774	PSP1 C-terminal conserved region
SGLY_RS00865	COG4467	Involved in initiation control of chromosome replication
SGLY_RS00870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SGLY_RS00875	COG2002	toxin-antitoxin pair type II binding
SGLY_RS00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGLY_RS00880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SGLY_RS00885	COG0084	hydrolase, TatD family'
SGLY_RS00935	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SGLY_RS00945	COG0840	transmembrane signaling receptor activity
SGLY_RS00955	COG4242	Belongs to the peptidase S51 family
SGLY_RS00960	COG0189	ligase activity
SGLY_RS00960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGLY_RS00970	COG1802	Transcriptional regulator
SGLY_RS00975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SGLY_RS00990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SGLY_RS01005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SGLY_RS01010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SGLY_RS01015	COG2002	toxin-antitoxin pair type II binding
SGLY_RS01020	COG3956	TIGRFAM MazG family protein
SGLY_RS01030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SGLY_RS01060	COG0037	tRNA processing
SGLY_RS01085	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SGLY_RS01090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SGLY_RS01095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SGLY_RS01100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SGLY_RS01115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SGLY_RS01120	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SGLY_RS01135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SGLY_RS01140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SGLY_RS01145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SGLY_RS01180	COG2195	Cleaves the N-terminal amino acid of tripeptides
SGLY_RS01190	COG1215	transferase activity, transferring glycosyl groups
SGLY_RS01205	COG2814	Major facilitator Superfamily
SGLY_RS01285	COG3949	Membrane
SGLY_RS01300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SGLY_RS01305	COG3481	metal-dependent phosphohydrolase, HD sub domain
SGLY_RS01310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SGLY_RS01320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SGLY_RS01325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGLY_RS01350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SGLY_RS01355	COG0826	peptidase U32
SGLY_RS01360	COG1193	negative regulation of DNA recombination
SGLY_RS01370	COG1309	transcriptional regulator
SGLY_RS01375	COG5002	protein histidine kinase activity
SGLY_RS01380	COG0745	RESPONSE REGULATOR receiver
SGLY_RS01385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SGLY_RS01385	COG4499	WXG100 protein secretion system (Wss), protein YukC
SGLY_RS01390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SGLY_RS01420	COG0235	Class ii aldolase
SGLY_RS01440	COG3546	catalase activity
SGLY_RS01450	COG3458	cephalosporin-C deacetylase activity
SGLY_RS01460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGLY_RS01465	COG3152	Membrane
SGLY_RS01480	COG1136	(ABC) transporter
SGLY_RS01490	COG1136	(ABC) transporter
SGLY_RS01500	COG1785	Belongs to the alkaline phosphatase family
SGLY_RS01515	COG1132	(ABC) transporter
SGLY_RS01540	COG1331	Highly conserved protein containing a thioredoxin domain
SGLY_RS01570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SGLY_RS01575	COG0542	response to heat
SGLY_RS01580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SGLY_RS01590	COG4956	integral membrane protein (PIN domain superfamily)
SGLY_RS01595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SGLY_RS01605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SGLY_RS01615	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SGLY_RS01625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SGLY_RS01655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SGLY_RS01675	COG1444	tRNA N-acetyltransferase activity
SGLY_RS01700	COG2002	toxin-antitoxin pair type II binding
SGLY_RS01935	COG3655	Transcriptional regulator
SGLY_RS01940	COG2333	competence protein COMEC
SGLY_RS01940	COG0658	competence protein
SGLY_RS01970	COG0840	transmembrane signaling receptor activity
SGLY_RS01975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGLY_RS01980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SGLY_RS01985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SGLY_RS01990	COG0250	Participates in transcription elongation, termination and antitermination
SGLY_RS01995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SGLY_RS02005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SGLY_RS02015	COG0085	RNA polymerase activity
SGLY_RS02020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SGLY_RS02025	COG1358	cellular component organization or biogenesis
SGLY_RS02040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGLY_RS02055	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SGLY_RS02060	COG0088	Forms part of the polypeptide exit tunnel
SGLY_RS02065	COG0089	rRNA binding
SGLY_RS02080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SGLY_RS02085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SGLY_RS02090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SGLY_RS02100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SGLY_RS02105	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SGLY_RS02110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SGLY_RS02135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SGLY_RS02145	COG0200	Binds to the 23S rRNA
SGLY_RS02150	COG0201	protein transport
SGLY_RS02165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SGLY_RS02190	COG0203	ribosomal protein L17
SGLY_RS02195	COG0101	tRNA pseudouridine synthase activity
SGLY_RS02215	COG0861	Integral membrane protein TerC family
SGLY_RS02220	COG0589	response to stress
SGLY_RS02225	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS02230	COG1473	amidohydrolase
SGLY_RS02235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SGLY_RS02240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SGLY_RS02245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SGLY_RS02250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SGLY_RS02255	COG0505	Belongs to the CarA family
SGLY_RS02260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SGLY_RS02265	COG0436	Aminotransferase
SGLY_RS02280	COG1983	PspC domain protein
SGLY_RS02305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SGLY_RS02315	COG2059	Chromate
SGLY_RS02320	COG2059	Chromate
SGLY_RS02325	COG0501	Belongs to the peptidase M48B family
SGLY_RS02330	COG0861	Integral membrane protein TerC family
SGLY_RS02340	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
SGLY_RS02345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SGLY_RS02365	COG0681	Belongs to the peptidase S26 family
SGLY_RS02380	COG2155	Conserved Protein
SGLY_RS02400	COG0436	Aminotransferase
SGLY_RS02405	COG1191	sigma factor activity
SGLY_RS02430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGLY_RS02435	COG4149	molybdate abc transporter
SGLY_RS02440	COG0725	ABC transporter, periplasmic molybdate-binding protein
SGLY_RS02445	COG1910	domain protein
SGLY_RS02460	COG0564	pseudouridine synthase activity
SGLY_RS02470	COG5002	protein histidine kinase activity
SGLY_RS02475	COG0745	RESPONSE REGULATOR receiver
SGLY_RS02510	COG1694	Mazg nucleotide pyrophosphohydrolase
SGLY_RS02515	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SGLY_RS02525	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SGLY_RS02530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGLY_RS02535	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SGLY_RS02540	COG0517	IMP dehydrogenase activity
SGLY_RS02540	COG4175	Glycine betaine
SGLY_RS02545	COG4176	ABC-type proline glycine betaine transport system permease component
SGLY_RS02550	COG2113	Glycine betaine
SGLY_RS02555	COG0038	chloride channel
SGLY_RS02560	COG0569	domain protein
SGLY_RS02565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SGLY_RS02570	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SGLY_RS02575	COG2720	vancomycin resistance protein
SGLY_RS02590	COG0745	RESPONSE REGULATOR receiver
SGLY_RS02595	COG5002	protein histidine kinase activity
SGLY_RS02600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
SGLY_RS02605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SGLY_RS02610	COG4208	sulfate ABC transporter
SGLY_RS02625	COG0175	sulfate reduction
SGLY_RS02645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SGLY_RS02660	COG0425	Belongs to the sulfur carrier protein TusA family
SGLY_RS02665	COG2873	o-acetylhomoserine
SGLY_RS02680	COG1648	precorrin-2 dehydrogenase activity
SGLY_RS02680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SGLY_RS02780	COG4383	Mu-like prophage protein gp29
SGLY_RS02785	COG2369	cell adhesion
SGLY_RS02800	COG4397	Mu-like prophage major head subunit gpT
SGLY_RS02940	COG1215	transferase activity, transferring glycosyl groups
SGLY_RS02945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGLY_RS02950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGLY_RS02955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGLY_RS02970	COG2747	anti-sigma28 factor FlgM
SGLY_RS02980	COG4786	Flagellar basal body rod
SGLY_RS02980	COG1256	bacterial-type flagellum assembly
SGLY_RS02995	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SGLY_RS03015	COG0463	Glycosyl transferase, family 2
SGLY_RS03015	COG0457	Tetratricopeptide repeat
SGLY_RS03020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SGLY_RS03035	COG1516	flagellar protein fliS
SGLY_RS03045	COG2198	Histidine kinase
SGLY_RS03045	COG0643	Histidine kinase
SGLY_RS03055	COG2201	protein-glutamate methylesterase activity
SGLY_RS03060	COG1558	bacterial-type flagellum-dependent cell motility
SGLY_RS03070	COG1766	The M ring may be actively involved in energy transduction
SGLY_RS03075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SGLY_RS03085	COG1157	protein secretion by the type III secretion system
SGLY_RS03105	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SGLY_RS03110	COG1776	CheC inhibitor of MCP methylation
SGLY_RS03110	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SGLY_RS03115	COG2201	protein-glutamate methylesterase activity
SGLY_RS03125	COG1338	Plays a role in the flagellum-specific transport system
SGLY_RS03130	COG1987	bacterial-type flagellum assembly
SGLY_RS03135	COG1684	flagellar biosynthetic protein fliR
SGLY_RS03140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SGLY_RS03145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SGLY_RS03150	COG1419	protein localization to endoplasmic reticulum
SGLY_RS03165	COG1776	CheC inhibitor of MCP methylation
SGLY_RS03180	COG1191	sigma factor activity
SGLY_RS03190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SGLY_RS03195	COG4786	Flagellar basal body rod
SGLY_RS03200	COG4786	Flagellar basal body rod
SGLY_RS03205	COG1815	bacterial-type flagellum-dependent cell motility
SGLY_RS03225	COG4862	establishment of competence for transformation
SGLY_RS03235	COG1316	TRANSCRIPTIONal
SGLY_RS03255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SGLY_RS03260	COG2221	Nitrite and sulphite reductase 4Fe-4S
SGLY_RS03265	COG0735	belongs to the Fur family
SGLY_RS03285	COG2001	Belongs to the MraZ family
SGLY_RS03300	COG0768	penicillin binding
SGLY_RS03305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SGLY_RS03310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SGLY_RS03325	COG0772	Belongs to the SEDS family
SGLY_RS03330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGLY_RS03335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SGLY_RS03340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGLY_RS03345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SGLY_RS03350	COG3856	small basic protein
SGLY_RS03355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SGLY_RS03365	COG1191	sigma factor activity
SGLY_RS03370	COG1191	sigma factor activity
SGLY_RS03375	COG1873	PFAM PRC-barrel domain
SGLY_RS03390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SGLY_RS03395	COG1799	cell septum assembly
SGLY_RS03425	COG0840	transmembrane signaling receptor activity
SGLY_RS03430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGLY_RS03445	COG4869	propanediol catabolic process
SGLY_RS03455	COG0564	pseudouridine synthase activity
SGLY_RS03460	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SGLY_RS03470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SGLY_RS03475	COG0505	Belongs to the CarA family
SGLY_RS03485	COG0543	2 iron, 2 sulfur cluster binding
SGLY_RS03490	COG0167	dihydroorotate dehydrogenase activity
SGLY_RS03495	COG0284	orotidine-5'-phosphate decarboxylase activity
SGLY_RS03500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SGLY_RS03520	COG5002	protein histidine kinase activity
SGLY_RS03530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SGLY_RS03540	COG1561	YicC-like family, N-terminal region
SGLY_RS03550	COG0194	GDP metabolic process
SGLY_RS03560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGLY_RS03570	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SGLY_RS03585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGLY_RS03590	COG2210	Belongs to the sulfur carrier protein TusA family
SGLY_RS03595	COG0372	Belongs to the citrate synthase family
SGLY_RS03610	COG2720	vancomycin resistance protein
SGLY_RS03620	COG4496	protein, YerC YecD
SGLY_RS03625	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SGLY_RS03640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SGLY_RS03650	COG0131	Imidazoleglycerol-phosphate dehydratase
SGLY_RS03670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SGLY_RS03670	COG0140	phosphoribosyl-ATP diphosphatase activity
SGLY_RS03680	COG0210	DNA helicase
SGLY_RS03690	COG0837	glucose binding
SGLY_RS03695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGLY_RS03720	COG0154	amidase activity
SGLY_RS03725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SGLY_RS03730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLY_RS03770	COG3328	transposase activity
SGLY_RS03790	COG4585	Histidine kinase
SGLY_RS03795	COG2197	response regulator
SGLY_RS04020	COG3778	Protein conserved in bacteria
SGLY_RS04070	COG4978	Transcriptional regulator
SGLY_RS04070	COG0789	Transcriptional regulator
SGLY_RS04095	COG1116	anion transmembrane transporter activity
SGLY_RS04105	COG3665	Urea carboxylase-associated protein
SGLY_RS04110	COG0439	Biotin carboxylase
SGLY_RS04120	COG1268	BioY protein
SGLY_RS04125	COG1122	ATPase activity
SGLY_RS04130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGLY_RS04150	COG4942	peptidase
SGLY_RS04180	COG1595	DNA-templated transcription, initiation
SGLY_RS04210	COG2226	methyltransferase
SGLY_RS04215	COG1131	(ABC) transporter
SGLY_RS04240	COG2197	response regulator
SGLY_RS04245	COG4585	Histidine kinase
SGLY_RS04255	COG0142	geranyltranstransferase activity
SGLY_RS04260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLY_RS04330	COG3290	protein histidine kinase activity
SGLY_RS04340	COG3279	Response regulator of the LytR AlgR family
SGLY_RS04350	COG0644	oxidoreductase
SGLY_RS04355	COG0463	Glycosyl transferase, family 2
SGLY_RS04365	COG0535	radical SAM domain protein
SGLY_RS04370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SGLY_RS04395	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SGLY_RS04395	COG0662	Cupin 2, conserved barrel domain protein
SGLY_RS04415	COG1136	(ABC) transporter
SGLY_RS04415	COG0577	efflux transmembrane transporter activity
SGLY_RS04435	COG1201	RNA secondary structure unwinding
SGLY_RS04460	COG3279	Response regulator of the LytR AlgR family
SGLY_RS04470	COG0745	RESPONSE REGULATOR receiver
SGLY_RS04475	COG5002	protein histidine kinase activity
SGLY_RS04480	COG1368	sulfuric ester hydrolase activity
SGLY_RS04495	COG2249	NAD(P)H dehydrogenase (quinone) activity
SGLY_RS04515	COG2814	Major facilitator Superfamily
SGLY_RS04570	COG1518	maintenance of DNA repeat elements
SGLY_RS04585	COG2873	o-acetylhomoserine
SGLY_RS04625	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGLY_RS04635	COG0655	NAD(P)H dehydrogenase (quinone) activity
SGLY_RS04640	COG3344	reverse transcriptase
SGLY_RS04660	COG2094	Belongs to the DNA glycosylase MPG family
SGLY_RS04670	COG1473	amidohydrolase
SGLY_RS04695	COG0626	cystathionine gamma-synthase activity
SGLY_RS04715	COG0500	methyltransferase
SGLY_RS04715	COG3615	Tellurite resistance protein tehB
SGLY_RS04735	COG1132	(ABC) transporter
SGLY_RS04740	COG1132	(ABC) transporter
SGLY_RS04755	COG1131	(ABC) transporter
SGLY_RS04770	COG3214	Protein conserved in bacteria
SGLY_RS04800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SGLY_RS04830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SGLY_RS04835	COG1619	proteins homologs of microcin C7 resistance protein MccF
SGLY_RS04840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGLY_RS04845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SGLY_RS04850	COG2515	1-aminocyclopropane-1-carboxylate deaminase
SGLY_RS04875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLY_RS04880	COG1846	Transcriptional regulator
SGLY_RS04885	COG2814	Major facilitator Superfamily
SGLY_RS04895	COG0347	Belongs to the P(II) protein family
SGLY_RS04905	COG1116	anion transmembrane transporter activity
SGLY_RS04915	COG0010	Belongs to the arginase family
SGLY_RS04925	COG3835	regulator
SGLY_RS04930	COG0831	urea catabolic process
SGLY_RS04935	COG0832	Belongs to the urease beta subunit family
SGLY_RS04940	COG0804	urea catabolic process
SGLY_RS04945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SGLY_RS04950	COG0830	nickel cation binding
SGLY_RS04960	COG0829	nickel cation binding
SGLY_RS04970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLY_RS04975	COG0577	efflux transmembrane transporter activity
SGLY_RS04975	COG1136	(ABC) transporter
SGLY_RS04980	COG1136	(ABC) transporter
SGLY_RS04990	COG5002	protein histidine kinase activity
SGLY_RS04995	COG0745	RESPONSE REGULATOR receiver
SGLY_RS05005	COG1393	Belongs to the ArsC family
SGLY_RS05025	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS05035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS05045	COG0500	methyltransferase
SGLY_RS05055	COG3335	DDE superfamily endonuclease
SGLY_RS05090	COG4895	conserved protein (DUF2196)
SGLY_RS05100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SGLY_RS05105	COG0242	peptide deformylase activity
SGLY_RS05110	COG1132	(ABC) transporter
SGLY_RS05115	COG1132	(ABC) transporter
SGLY_RS05130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS05140	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
SGLY_RS05165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SGLY_RS05175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SGLY_RS05235	COG0577	efflux transmembrane transporter activity
SGLY_RS05235	COG1136	(ABC) transporter
SGLY_RS05255	COG1136	(ABC) transporter
SGLY_RS05255	COG0577	efflux transmembrane transporter activity
SGLY_RS05305	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SGLY_RS05340	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SGLY_RS05340	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SGLY_RS05390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGLY_RS05390	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SGLY_RS05435	COG0564	pseudouridine synthase activity
SGLY_RS05450	COG1595	DNA-templated transcription, initiation
SGLY_RS05460	COG0515	serine threonine protein kinase
SGLY_RS05470	COG0745	RESPONSE REGULATOR receiver
SGLY_RS05475	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SGLY_RS05480	COG1749	Flagellar hook protein flgE
SGLY_RS05485	COG1256	bacterial-type flagellum assembly
SGLY_RS05485	COG4786	Flagellar basal body rod
SGLY_RS05490	COG1256	bacterial-type flagellum assembly
SGLY_RS05490	COG4786	Flagellar basal body rod
SGLY_RS05500	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SGLY_RS05510	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SGLY_RS05525	COG5002	protein histidine kinase activity
SGLY_RS05530	COG0745	RESPONSE REGULATOR receiver
SGLY_RS05575	COG0765	amino acid transport
SGLY_RS05580	COG0765	amino acid transport
SGLY_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SGLY_RS05595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGLY_RS05600	COG1140	nitrate reductase beta subunit
SGLY_RS05610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SGLY_RS05610	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGLY_RS05620	COG1126	abc transporter atp-binding protein
SGLY_RS05625	COG1253	flavin adenine dinucleotide binding
SGLY_RS05640	COG2766	serine protein kinase
SGLY_RS05645	COG2718	Belongs to the UPF0229 family
SGLY_RS05650	COG2719	SpoVR family
SGLY_RS05670	COG2814	Major facilitator Superfamily
SGLY_RS05675	COG2030	dehydratase
SGLY_RS05690	COG0318	PFAM AMP-dependent synthetase and ligase
SGLY_RS05705	COG1960	acyl-CoA dehydrogenase activity
SGLY_RS05710	COG0644	oxidoreductase
SGLY_RS05725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SGLY_RS05735	COG1012	belongs to the aldehyde dehydrogenase family
SGLY_RS05740	COG0513	Belongs to the DEAD box helicase family
SGLY_RS05745	COG1595	DNA-templated transcription, initiation
SGLY_RS05775	COG0745	RESPONSE REGULATOR receiver
SGLY_RS05780	COG2205	protein histidine kinase activity
SGLY_RS05785	COG1136	(ABC) transporter
SGLY_RS05790	COG0577	efflux transmembrane transporter activity
SGLY_RS05795	COG1309	transcriptional regulator
SGLY_RS05810	COG1335	isochorismatase
SGLY_RS05825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLY_RS05855	COG1129	ABC transporter
SGLY_RS05875	COG3123	guanosine phosphorylase activity
SGLY_RS05895	COG2197	response regulator
SGLY_RS05900	COG2198	Histidine kinase
SGLY_RS05900	COG0643	Histidine kinase
SGLY_RS05905	COG0835	chemotaxis
SGLY_RS05915	COG2201	protein-glutamate methylesterase activity
SGLY_RS05920	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SGLY_RS05930	COG2201	protein-glutamate methylesterase activity
SGLY_RS05935	COG0840	transmembrane signaling receptor activity
SGLY_RS05940	COG2199	diguanylate cyclase activity
SGLY_RS05940	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SGLY_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
SGLY_RS05965	COG2378	regulation of single-species biofilm formation
SGLY_RS05985	COG1136	(ABC) transporter
SGLY_RS05995	COG0745	RESPONSE REGULATOR receiver
SGLY_RS06025	COG0668	transmembrane transport
SGLY_RS06030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SGLY_RS06040	COG2409	Drug exporters of the RND superfamily
SGLY_RS06040	COG1033	growth of symbiont in host cell
SGLY_RS06060	COG0446	pyridine nucleotide-disulphide oxidoreductase
SGLY_RS06060	COG1902	pentaerythritol trinitrate reductase activity
SGLY_RS06065	COG1129	ABC transporter
SGLY_RS06095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGLY_RS06150	COG2378	regulation of single-species biofilm formation
SGLY_RS06175	COG4591	ABC-type transport system involved in lipoprotein release permease component
SGLY_RS06175	COG1136	(ABC) transporter
SGLY_RS06180	COG5002	protein histidine kinase activity
SGLY_RS06185	COG0745	RESPONSE REGULATOR receiver
SGLY_RS06195	COG1132	(ABC) transporter
SGLY_RS06195	COG2375	cellular response to nickel ion
SGLY_RS06210	COG1309	transcriptional regulator
SGLY_RS06215	COG1131	(ABC) transporter
SGLY_RS06255	COG1136	(ABC) transporter
SGLY_RS06265	COG0745	RESPONSE REGULATOR receiver
SGLY_RS06280	COG1131	(ABC) transporter
SGLY_RS06300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SGLY_RS06315	COG0420	3'-5' exonuclease activity
SGLY_RS06320	COG0419	ATPase involved in DNA repair
SGLY_RS06330	COG1937	Protein conserved in bacteria
SGLY_RS06450	COG1131	(ABC) transporter
SGLY_RS06460	COG1595	DNA-templated transcription, initiation
SGLY_RS06485	COG1595	DNA-templated transcription, initiation
SGLY_RS06520	COG2378	regulation of single-species biofilm formation
SGLY_RS06530	COG0426	domain, Protein
SGLY_RS06530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGLY_RS06535	COG2378	regulation of single-species biofilm formation
SGLY_RS06580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SGLY_RS06590	COG1124	(ABC) transporter
SGLY_RS06600	COG0601	transmembrane transport
SGLY_RS06625	COG2226	methyltransferase
SGLY_RS06645	COG1122	ATPase activity
SGLY_RS06650	COG1122	ATPase activity
SGLY_RS06655	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGLY_RS06670	COG3620	sequence-specific DNA binding
SGLY_RS06705	COG1120	ATPase activity
SGLY_RS06710	COG1609	Transcriptional regulator
SGLY_RS06710	COG2207	Transcriptional regulator
SGLY_RS06715	COG1132	(ABC) transporter
SGLY_RS06715	COG2375	cellular response to nickel ion
SGLY_RS06720	COG1132	(ABC) transporter
SGLY_RS06800	COG1131	(ABC) transporter
SGLY_RS06820	COG2807	transmembrane transport
SGLY_RS06835	COG5646	InterPro IPR014922
SGLY_RS06865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SGLY_RS06870	COG1454	alcohol dehydrogenase
SGLY_RS06890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SGLY_RS06890	COG0167	dihydroorotate dehydrogenase activity
SGLY_RS06895	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SGLY_RS06905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS06945	COG1518	maintenance of DNA repeat elements
SGLY_RS06950	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SGLY_RS06965	COG2205	protein histidine kinase activity
SGLY_RS06970	COG0745	RESPONSE REGULATOR receiver
SGLY_RS06980	COG1136	(ABC) transporter
SGLY_RS06995	COG0386	Belongs to the glutathione peroxidase family
SGLY_RS07000	COG1846	Transcriptional regulator
SGLY_RS07010	COG2183	response to ionizing radiation
SGLY_RS07020	COG1131	(ABC) transporter
SGLY_RS07025	COG0753	catalase activity
SGLY_RS07025	COG0693	protein deglycase activity
SGLY_RS07035	COG0535	radical SAM domain protein
SGLY_RS07040	COG0535	radical SAM domain protein
SGLY_RS07045	COG1522	sequence-specific DNA binding
SGLY_RS07050	COG1316	TRANSCRIPTIONal
SGLY_RS07115	COG1342	Belongs to the UPF0251 family
SGLY_RS07120	COG0157	Belongs to the NadC ModD family
SGLY_RS07125	COG0025	NhaP-type Na H and K H
SGLY_RS07135	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SGLY_RS07140	COG2814	Major facilitator Superfamily
SGLY_RS07150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SGLY_RS07170	COG2873	o-acetylhomoserine
SGLY_RS07190	COG2873	o-acetylhomoserine
SGLY_RS07195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGLY_RS07200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS07215	COG3177	Filamentation induced by cAMP protein fic
SGLY_RS07245	COG1131	(ABC) transporter
SGLY_RS07330	COG1253	flavin adenine dinucleotide binding
SGLY_RS07355	COG0641	radical SAM
SGLY_RS07360	COG2186	Transcriptional regulator
SGLY_RS07365	COG4988	ABC transporter
SGLY_RS07370	COG1132	(ABC) transporter
SGLY_RS07380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGLY_RS07385	COG1122	ATPase activity
SGLY_RS07415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGLY_RS07435	COG1120	ATPase activity
SGLY_RS07465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGLY_RS07475	COG1321	iron dependent repressor
SGLY_RS07480	COG0803	Belongs to the bacterial solute-binding protein 9 family
SGLY_RS07485	COG1121	(ABC) transporter
SGLY_RS07490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGLY_RS07495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SGLY_RS07500	COG2247	cell wall binding repeat
SGLY_RS07500	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS07505	COG3437	response regulator, receiver
SGLY_RS07520	COG3944	biosynthesis protein
SGLY_RS07525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGLY_RS07565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGLY_RS07570	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SGLY_RS07590	COG0582	viral genome integration into host DNA
SGLY_RS07595	COG2217	Heavy metal translocating P-type atpase
SGLY_RS07600	COG0640	Transcriptional regulator
SGLY_RS07615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SGLY_RS07635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGLY_RS07650	COG1132	(ABC) transporter
SGLY_RS07660	COG0583	DNA-binding transcription factor activity
SGLY_RS07665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SGLY_RS07670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS07675	COG1116	anion transmembrane transporter activity
SGLY_RS07695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGLY_RS07700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLY_RS07705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SGLY_RS07710	COG0789	Transcriptional regulator
SGLY_RS07730	COG0463	Glycosyl transferase, family 2
SGLY_RS07730	COG0457	Tetratricopeptide repeat
SGLY_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
SGLY_RS07805	COG0110	maltose O-acetyltransferase activity
SGLY_RS07850	COG1132	(ABC) transporter
SGLY_RS07850	COG2375	cellular response to nickel ion
SGLY_RS07855	COG1132	(ABC) transporter
SGLY_RS07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SGLY_RS07870	COG0723	plastoquinol--plastocyanin reductase activity
SGLY_RS07890	COG2199	diguanylate cyclase activity
SGLY_RS07890	COG2203	Gaf domain
SGLY_RS07895	COG0531	amino acid
SGLY_RS07900	COG0671	phosphoesterase, PA-phosphatase related
SGLY_RS07915	COG2326	polyphosphate kinase activity
SGLY_RS07920	COG1704	LemA family
SGLY_RS07930	COG4224	UPF0291 protein
SGLY_RS07935	COG0538	isocitrate dehydrogenase activity
SGLY_RS07940	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS07940	COG2247	cell wall binding repeat
SGLY_RS07950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SGLY_RS07960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SGLY_RS07960	COG0517	IMP dehydrogenase activity
SGLY_RS07965	COG0561	phosphatase activity
SGLY_RS07980	COG0463	Glycosyl transferase, family 2
SGLY_RS07985	COG0438	transferase activity, transferring glycosyl groups
SGLY_RS07990	COG1215	transferase activity, transferring glycosyl groups
SGLY_RS08030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SGLY_RS08045	COG3944	biosynthesis protein
SGLY_RS08050	COG0489	protein tyrosine kinase activity
SGLY_RS08060	COG0367	asparagine synthase
SGLY_RS08080	COG1132	(ABC) transporter
SGLY_RS08085	COG1408	metallophosphoesterase
SGLY_RS08100	COG0590	tRNA wobble adenosine to inosine editing
SGLY_RS08110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGLY_RS08115	COG1253	flavin adenine dinucleotide binding
SGLY_RS08125	COG1307	EDD domain protein, DegV family
SGLY_RS08130	COG2050	protein possibly involved in aromatic compounds catabolism
SGLY_RS08135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SGLY_RS08140	COG1454	alcohol dehydrogenase
SGLY_RS08145	COG2814	Major facilitator Superfamily
SGLY_RS08160	COG1136	(ABC) transporter
SGLY_RS08165	COG0577	efflux transmembrane transporter activity
SGLY_RS08165	COG1136	(ABC) transporter
SGLY_RS08170	COG2247	cell wall binding repeat
SGLY_RS08170	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS08180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SGLY_RS08190	COG5002	protein histidine kinase activity
SGLY_RS08195	COG0463	Glycosyl transferase, family 2
SGLY_RS08210	COG0784	Response regulator, receiver
SGLY_RS08210	COG0835	chemotaxis
SGLY_RS08215	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SGLY_RS08220	COG1773	rubredoxin
SGLY_RS08220	COG1592	Rubrerythrin
SGLY_RS08230	COG2022	thiamine diphosphate biosynthetic process
SGLY_RS08235	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGLY_RS08240	COG0352	thiamine-phosphate diphosphorylase activity
SGLY_RS08245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SGLY_RS08255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SGLY_RS08260	COG2188	Transcriptional regulator
SGLY_RS08265	COG1131	(ABC) transporter
SGLY_RS08285	COG1136	(ABC) transporter
SGLY_RS08290	COG0577	efflux transmembrane transporter activity
SGLY_RS08305	COG0306	phosphate transporter
SGLY_RS08320	COG0735	belongs to the Fur family
SGLY_RS08325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SGLY_RS08330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SGLY_RS08340	COG3874	Sporulation protein YtfJ
SGLY_RS08345	COG2715	membrane protein required for spore maturation
SGLY_RS08350	COG0700	Nucleoside recognition
SGLY_RS08355	COG1187	pseudouridine synthase activity
SGLY_RS08360	COG2186	Transcriptional regulator
SGLY_RS08365	COG2186	Transcriptional regulator
SGLY_RS08375	COG2081	HI0933 family
SGLY_RS08415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SGLY_RS08415	COG0539	negative regulation of cytoplasmic translation
SGLY_RS08420	COG0772	Belongs to the SEDS family
SGLY_RS08430	COG1160	GTP binding
SGLY_RS08435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SGLY_RS08440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SGLY_RS08445	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SGLY_RS08450	COG4492	Belongs to the UPF0735 family
SGLY_RS08485	COG0598	Magnesium transport protein CorA
SGLY_RS08505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SGLY_RS08510	COG0805	protein transport
SGLY_RS08515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGLY_RS08520	COG0142	geranyltranstransferase activity
SGLY_RS08530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SGLY_RS08555	COG0726	polysaccharide deacetylase
SGLY_RS08575	COG0163	prenyltransferase activity
SGLY_RS08605	COG0564	pseudouridine synthase activity
SGLY_RS08625	COG0436	Aminotransferase
SGLY_RS08650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SGLY_RS08655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SGLY_RS08660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SGLY_RS08670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SGLY_RS08690	COG1131	(ABC) transporter
SGLY_RS08710	COG1309	transcriptional regulator
SGLY_RS08740	COG1388	LysM domain
SGLY_RS08750	COG1181	Belongs to the D-alanine--D-alanine ligase family
SGLY_RS08760	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SGLY_RS08765	COG0464	growth
SGLY_RS08775	COG1923	regulation of RNA biosynthetic process
SGLY_RS08780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SGLY_RS08785	COG2136	Putative SAM-dependent methyltransferase
SGLY_RS08785	COG2521	methyltransferase
SGLY_RS08790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SGLY_RS08805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SGLY_RS08820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLY_RS08825	COG1307	EDD domain protein, DegV family
SGLY_RS08850	COG1691	(AIR) carboxylase
SGLY_RS08860	COG1363	Peptidase, m42
SGLY_RS08870	COG0768	penicillin binding
SGLY_RS08875	COG0457	Tetratricopeptide repeat
SGLY_RS08875	COG0705	Rhomboid family
SGLY_RS08885	COG1615	UPF0182 protein
SGLY_RS08890	COG2197	response regulator
SGLY_RS08900	COG1484	DNA-dependent DNA replication
SGLY_RS08905	COG3935	DnaD domain protein
SGLY_RS08915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SGLY_RS08940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGLY_RS08940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SGLY_RS08950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGLY_RS08950	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SGLY_RS08960	COG2267	carboxylic ester hydrolase activity
SGLY_RS08980	COG0778	Nitroreductase
SGLY_RS08990	COG1131	(ABC) transporter
SGLY_RS08995	COG1725	Transcriptional regulator
SGLY_RS09005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLY_RS09015	COG1132	(ABC) transporter
SGLY_RS09020	COG1132	(ABC) transporter
SGLY_RS09020	COG2375	cellular response to nickel ion
SGLY_RS09025	COG0747	negative chemotaxis
SGLY_RS09030	COG1124	(ABC) transporter
SGLY_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLY_RS09045	COG0601	transmembrane transport
SGLY_RS09050	COG1917	Cupin 2, conserved barrel domain protein
SGLY_RS09050	COG2207	Transcriptional regulator
SGLY_RS09055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGLY_RS09060	COG0542	response to heat
SGLY_RS09065	COG0484	heat shock protein binding
SGLY_RS09070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SGLY_RS09070	COG2755	lipolytic protein G-D-S-L family
SGLY_RS09075	COG0745	RESPONSE REGULATOR receiver
SGLY_RS09080	COG5002	protein histidine kinase activity
SGLY_RS09100	COG0347	Belongs to the P(II) protein family
SGLY_RS09105	COG0668	transmembrane transport
SGLY_RS09120	COG2962	Rard protein
SGLY_RS09155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGLY_RS09165	COG0133	tryptophan synthase activity
SGLY_RS09175	COG2721	sulfolactate sulfo-lyase activity
SGLY_RS09180	COG2721	sulfolactate sulfo-lyase activity
SGLY_RS09185	COG0367	asparagine synthase
SGLY_RS09200	COG2323	membrane
SGLY_RS09210	COG1295	ribonuclease BN
SGLY_RS09220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SGLY_RS09230	COG0180	Tryptophanyl-tRNA synthetase
SGLY_RS09235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGLY_RS09235	COG3620	sequence-specific DNA binding
SGLY_RS09235	COG0617	tRNA 3'-terminal CCA addition
SGLY_RS09250	COG0697	spore germination
SGLY_RS09260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGLY_RS09270	COG1366	Belongs to the anti-sigma-factor antagonist family
SGLY_RS09275	COG2172	sigma factor antagonist activity
SGLY_RS09285	COG1686	Belongs to the peptidase S11 family
SGLY_RS09300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SGLY_RS09310	COG4974	Belongs to the 'phage' integrase family
SGLY_RS09315	COG1300	Membrane
SGLY_RS09320	COG0494	nUDIX hydrolase
SGLY_RS09325	COG0745	RESPONSE REGULATOR receiver
SGLY_RS09330	COG0750	zinc metalloprotease
SGLY_RS09355	COG1216	Glycosyl transferase, family 2
SGLY_RS09360	COG0497	DNA recombination
SGLY_RS09375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SGLY_RS09380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SGLY_RS09385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SGLY_RS09390	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SGLY_RS09400	COG1722	exodeoxyribonuclease VII activity
SGLY_RS09405	COG1570	exodeoxyribonuclease VII activity
SGLY_RS09410	COG3404	Formiminotransferase-cyclodeaminase
SGLY_RS09415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SGLY_RS09455	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SGLY_RS09470	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SGLY_RS09475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGLY_RS09495	COG1302	Protein conserved in bacteria
SGLY_RS09535	COG3854	ATPases associated with a variety of cellular activities
SGLY_RS09545	COG0006	proline dipeptidase activity
SGLY_RS09575	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SGLY_RS09580	COG2165	general secretion pathway protein
SGLY_RS09585	COG1459	type II secretion system
SGLY_RS09590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SGLY_RS09610	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SGLY_RS09620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SGLY_RS09655	COG0826	peptidase U32
SGLY_RS09660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SGLY_RS09665	COG3906	Belongs to the UPF0473 family
SGLY_RS09685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SGLY_RS09690	COG0628	permease
SGLY_RS09705	COG0822	iron-sulfur transferase activity
SGLY_RS09715	COG1959	2 iron, 2 sulfur cluster binding
SGLY_RS09750	COG0322	excinuclease ABC activity
SGLY_RS09755	COG0739	heme binding
SGLY_RS09765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SGLY_RS09775	COG1164	Oligoendopeptidase f
SGLY_RS09785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGLY_RS09795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SGLY_RS09810	COG0791	NLP P60 protein
SGLY_RS09810	COG1388	LysM domain
SGLY_RS09815	COG1368	sulfuric ester hydrolase activity
SGLY_RS09865	COG0789	Transcriptional regulator
SGLY_RS09880	COG3655	Transcriptional regulator
SGLY_RS09890	COG1937	Protein conserved in bacteria
SGLY_RS09895	COG2217	Heavy metal translocating P-type atpase
SGLY_RS09900	COG0488	(ABC) transporter
SGLY_RS09920	COG2261	transglycosylase associated protein
SGLY_RS09930	COG1136	(ABC) transporter
SGLY_RS09935	COG1136	(ABC) transporter
SGLY_RS09935	COG0577	efflux transmembrane transporter activity
SGLY_RS09940	COG3706	GGDEF domain
SGLY_RS09940	COG5001	Diguanylate cyclase
SGLY_RS09940	COG4251	negative regulation of phosphorylation
SGLY_RS09940	COG2203	Gaf domain
SGLY_RS09975	COG1131	(ABC) transporter
SGLY_RS09995	COG0024	Methionine aminopeptidase
SGLY_RS10050	COG2226	methyltransferase
SGLY_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
SGLY_RS10060	COG2996	Protein conserved in bacteria
SGLY_RS10065	COG0551	DNA topoisomerase type I activity
SGLY_RS10065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGLY_RS10085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGLY_RS10095	COG1139	Iron-sulfur cluster binding protein
SGLY_RS10145	COG0463	Glycosyl transferase, family 2
SGLY_RS10145	COG0457	Tetratricopeptide repeat
SGLY_RS10150	COG3459	Glycosyltransferase 36 associated
SGLY_RS10170	COG3328	transposase activity
SGLY_RS10190	COG1595	DNA-templated transcription, initiation
SGLY_RS10210	COG0409	Hydrogenase expression formation protein
SGLY_RS10225	COG0375	protein maturation
SGLY_RS10235	COG0649	NAD binding
SGLY_RS10245	COG3260	NADH ubiquinone oxidoreductase 20
SGLY_RS10250	COG0650	Formate hydrogenlyase subunit 4
SGLY_RS10255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SGLY_RS10255	COG2111	Na H antiporter
SGLY_RS10260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SGLY_RS10265	COG2244	polysaccharide biosynthetic process
SGLY_RS10280	COG0302	gtp cyclohydrolase
SGLY_RS10300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SGLY_RS10315	COG0849	cell division
SGLY_RS10320	COG0205	6-phosphofructokinase activity
SGLY_RS10325	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SGLY_RS10355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SGLY_RS10365	COG1595	DNA-templated transcription, initiation
SGLY_RS10375	COG0739	heme binding
SGLY_RS10400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SGLY_RS10405	COG0745	RESPONSE REGULATOR receiver
SGLY_RS10410	COG1141	Ferredoxin
SGLY_RS10420	COG1183	phosphatidylcholine synthase activity
SGLY_RS10425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SGLY_RS10425	COG1199	ATP-dependent helicase activity
SGLY_RS10435	COG2257	FlhB HrpN YscU SpaS Family
SGLY_RS10450	COG1937	Protein conserved in bacteria
SGLY_RS10455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SGLY_RS10465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGLY_RS10470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SGLY_RS10475	COG1490	D-aminoacyl-tRNA deacylase activity
SGLY_RS10480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SGLY_RS10485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SGLY_RS10485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SGLY_RS10500	COG0440	acetolactate synthase activity
SGLY_RS10505	COG0028	Belongs to the TPP enzyme family
SGLY_RS10510	COG1234	tRNA 3'-trailer cleavage
SGLY_RS10515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLY_RS10520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SGLY_RS10525	COG1862	Preprotein translocase
SGLY_RS10540	COG2385	sporulation resulting in formation of a cellular spore
SGLY_RS10550	COG0632	four-way junction helicase activity
SGLY_RS10565	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SGLY_RS10570	COG3177	Filamentation induced by cAMP protein fic
SGLY_RS10575	COG1132	(ABC) transporter
SGLY_RS10580	COG1132	(ABC) transporter
SGLY_RS10580	COG2375	cellular response to nickel ion
SGLY_RS10585	COG0747	negative chemotaxis
SGLY_RS10610	COG2207	Transcriptional regulator
SGLY_RS10615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SGLY_RS10625	COG2207	Transcriptional regulator
SGLY_RS10690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGLY_RS10695	COG1116	anion transmembrane transporter activity
SGLY_RS10700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS10705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SGLY_RS10710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SGLY_RS10720	COG0473	3-isopropylmalate dehydrogenase activity
SGLY_RS10725	COG0066	3-isopropylmalate dehydratase activity
SGLY_RS10730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SGLY_RS10735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLY_RS10745	COG0440	acetolactate synthase activity
SGLY_RS10750	COG0028	Belongs to the TPP enzyme family
SGLY_RS10760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SGLY_RS10765	COG0460	homoserine dehydrogenase
SGLY_RS10775	COG0741	lytic transglycosylase activity
SGLY_RS10775	COG0739	heme binding
SGLY_RS10775	COG1196	nuclear chromosome segregation
SGLY_RS10780	COG0237	dephospho-CoA kinase activity
SGLY_RS10790	COG0488	(ABC) transporter
SGLY_RS10815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLY_RS10820	COG1739	Uncharacterized protein family UPF0029
SGLY_RS10835	COG0517	IMP dehydrogenase activity
SGLY_RS10840	COG0004	ammonium transporteR
SGLY_RS10845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SGLY_RS10850	COG2226	methyltransferase
SGLY_RS10880	COG5557	Pfam Polysulphide reductase, NrfD
SGLY_RS10885	COG0437	4 iron, 4 sulfur cluster binding
SGLY_RS10885	COG3064	Membrane
SGLY_RS10895	COG5557	Pfam Polysulphide reductase, NrfD
SGLY_RS10900	COG0437	4 iron, 4 sulfur cluster binding
SGLY_RS10900	COG3064	Membrane
SGLY_RS10915	COG0281	malic enzyme
SGLY_RS10925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SGLY_RS10940	COG0328	RNA-DNA hybrid ribonuclease activity
SGLY_RS10945	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SGLY_RS10955	COG0704	Plays a role in the regulation of phosphate uptake
SGLY_RS10970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SGLY_RS10980	COG0436	Aminotransferase
SGLY_RS10995	COG2359	stage V sporulation protein S
SGLY_RS11000	COG1692	metallophosphoesterase
SGLY_RS11010	COG1418	mRNA catabolic process
SGLY_RS11020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SGLY_RS11025	COG1058	Belongs to the CinA family
SGLY_RS11025	COG1546	Belongs to the CinA family
SGLY_RS11030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SGLY_RS11035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLY_RS11040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SGLY_RS11045	COG1426	Protein conserved in bacteria
SGLY_RS11050	COG1674	ftsk spoiiie
SGLY_RS11055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SGLY_RS11060	COG0166	Belongs to the GPI family
SGLY_RS11090	COG0804	urea catabolic process
SGLY_RS11095	COG0832	Belongs to the urease beta subunit family
SGLY_RS11100	COG0831	urea catabolic process
SGLY_RS11120	COG0559	Belongs to the binding-protein-dependent transport system permease family
SGLY_RS11130	COG2207	Transcriptional regulator
SGLY_RS11130	COG4753	response regulator
SGLY_RS11140	COG4251	negative regulation of phosphorylation
SGLY_RS11215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SGLY_RS11220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SGLY_RS11225	COG0527	aspartate kinase activity
SGLY_RS11230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SGLY_RS11235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SGLY_RS11240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SGLY_RS11250	COG1873	PFAM PRC-barrel domain
SGLY_RS11265	COG0612	Peptidase, M16
SGLY_RS11270	COG1686	Belongs to the peptidase S11 family
SGLY_RS11285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SGLY_RS11290	COG0196	riboflavin kinase activity
SGLY_RS11300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SGLY_RS11310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGLY_RS11310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SGLY_RS11320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SGLY_RS11325	COG0195	Participates in both transcription termination and antitermination
SGLY_RS11330	COG0779	Required for maturation of 30S ribosomal subunits
SGLY_RS11345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SGLY_RS11350	COG0750	zinc metalloprotease
SGLY_RS11365	COG4589	Belongs to the CDS family
SGLY_RS11370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SGLY_RS11380	COG0233	cytoplasmic translational termination
SGLY_RS11385	COG0528	UMP kinase activity
SGLY_RS11420	COG4974	Belongs to the 'phage' integrase family
SGLY_RS11425	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SGLY_RS11430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SGLY_RS11435	COG0758	DNA mediated transformation
SGLY_RS11445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SGLY_RS11450	COG0791	NLP P60 protein
SGLY_RS11450	COG1388	LysM domain
SGLY_RS11460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SGLY_RS11465	COG0482	sulfurtransferase activity
SGLY_RS11470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SGLY_RS11475	COG1045	serine acetyltransferase
SGLY_RS11485	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SGLY_RS11500	COG2720	vancomycin resistance protein
SGLY_RS11505	COG1742	UPF0060 membrane protein
SGLY_RS11525	COG0606	chelatase, subunit chli
SGLY_RS11530	COG0840	transmembrane signaling receptor activity
SGLY_RS11545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SGLY_RS11555	COG4752	Belongs to the RNA methyltransferase TrmD family
SGLY_RS11560	COG0336	Belongs to the RNA methyltransferase TrmD family
SGLY_RS11565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SGLY_RS11570	COG1837	Belongs to the UPF0109 family
SGLY_RS11580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SGLY_RS11590	COG0402	S-adenosylhomocysteine deaminase activity
SGLY_RS11600	COG0552	protein localization to endoplasmic reticulum
SGLY_RS11605	COG1196	nuclear chromosome segregation
SGLY_RS11610	COG0571	ribonuclease III activity
SGLY_RS11625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SGLY_RS11640	COG3314	Sporulation integral membrane protein YlbJ
SGLY_RS11650	COG0742	ribosomal rna small subunit methyltransferase
SGLY_RS11655	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SGLY_RS11665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SGLY_RS11670	COG1760	l-serine dehydratase
SGLY_RS11675	COG1760	l-serine dehydratase
SGLY_RS11680	COG1461	Dihydroxyacetone kinase
SGLY_RS11685	COG1302	Protein conserved in bacteria
SGLY_RS11695	COG1564	THIamine pyrophosphokinase
SGLY_RS11700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SGLY_RS11705	COG1162	GTPase activity
SGLY_RS11710	COG0515	serine threonine protein kinase
SGLY_RS11710	COG2815	serine threonine protein kinase
SGLY_RS11715	COG0768	penicillin binding
SGLY_RS11725	COG0631	protein serine/threonine phosphatase activity
SGLY_RS11740	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SGLY_RS11745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGLY_RS11750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SGLY_RS11755	COG0242	peptide deformylase activity
SGLY_RS11760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SGLY_RS11775	COG0789	Transcriptional regulator
SGLY_RS11800	COG0640	Transcriptional regulator
SGLY_RS11810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SGLY_RS11820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SGLY_RS11825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGLY_RS11830	COG0047	phosphoribosylformylglycinamidine synthase activity
SGLY_RS11835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SGLY_RS11840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SGLY_RS11845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SGLY_RS11850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SGLY_RS11870	COG0251	oxidation-reduction process
SGLY_RS11875	COG1606	tRNA processing
SGLY_RS11885	COG1605	Chorismate mutase
SGLY_RS11885	COG0077	Prephenate dehydratase
SGLY_RS11890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SGLY_RS11895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SGLY_RS11900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SGLY_RS11910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SGLY_RS11920	COG1322	Protein conserved in bacteria
SGLY_RS11930	COG2959	enzyme of heme biosynthesis
SGLY_RS11965	COG0351	phosphomethylpyrimidine kinase
SGLY_RS11975	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SGLY_RS11980	COG0352	thiamine-phosphate diphosphorylase activity
SGLY_RS11990	COG1882	Formate acetyltransferase
SGLY_RS11995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGLY_RS12010	COG0697	spore germination
SGLY_RS12015	COG0436	Aminotransferase
SGLY_RS12035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SGLY_RS12040	COG2384	SAM-dependent methyltransferase
SGLY_RS12055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SGLY_RS12060	COG0358	DNA primase activity
SGLY_RS12065	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SGLY_RS12075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SGLY_RS12080	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SGLY_RS12115	COG3041	Addiction module toxin RelE StbE family
SGLY_RS12125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SGLY_RS12125	COG0574	Belongs to the PEP-utilizing enzyme family
SGLY_RS12135	COG0517	IMP dehydrogenase activity
SGLY_RS12150	COG1381	Involved in DNA repair and RecF pathway recombination
SGLY_RS12160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SGLY_RS12170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SGLY_RS12180	COG1480	7TM receptor with intracellular HD hydrolase
SGLY_RS12185	COG1702	phosphate starvation-inducible protein PhoH
SGLY_RS12210	COG0537	adenosine 5'-monophosphoramidase activity
SGLY_RS12220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SGLY_RS12225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SGLY_RS12230	COG2264	protein methyltransferase activity
SGLY_RS12245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SGLY_RS12255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SGLY_RS12265	COG0728	peptidoglycan biosynthetic process
SGLY_RS12295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SGLY_RS12305	COG1555	photosystem II stabilization
SGLY_RS12305	COG1596	polysaccharide export
SGLY_RS12320	COG0799	negative regulation of ribosome biogenesis
SGLY_RS12330	COG0724	RNA recognition motif
SGLY_RS12335	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SGLY_RS12340	COG1534	Rna-binding protein
SGLY_RS12360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SGLY_RS12380	COG4942	peptidase
SGLY_RS12385	COG0772	Belongs to the SEDS family
SGLY_RS12395	COG2894	cell division
SGLY_RS12415	COG1077	Cell shape determining protein MreB Mrl
SGLY_RS12425	COG0424	maF-like protein
SGLY_RS12430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLY_RS12450	COG0285	dihydrofolate synthase activity
SGLY_RS12455	COG0525	valine-tRNA ligase activity
SGLY_RS12465	COG2076	Multidrug Resistance protein
SGLY_RS12470	COG1216	Glycosyl transferase, family 2
SGLY_RS12495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SGLY_RS12500	COG1067	ATP-dependent peptidase activity
SGLY_RS12500	COG0470	DNA polymerase III
SGLY_RS12515	COG0544	peptidyl-prolyl cis-trans isomerase activity
SGLY_RS12520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SGLY_RS12525	COG1272	protein, Hemolysin III
SGLY_RS12535	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SGLY_RS12560	COG2894	cell division
SGLY_RS12585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SGLY_RS12600	COG1342	Belongs to the UPF0251 family
SGLY_RS12615	COG0252	asparaginase activity
SGLY_RS12620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS12625	COG2188	Transcriptional regulator
SGLY_RS12650	COG0277	FAD linked oxidase domain protein
SGLY_RS12660	COG0247	lactate metabolic process
SGLY_RS12670	COG3958	Transketolase
SGLY_RS12675	COG3959	Transketolase, thiamine diphosphate binding domain
SGLY_RS12685	COG1414	Transcriptional regulator
SGLY_RS12700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SGLY_RS12720	COG1609	Transcriptional regulator
SGLY_RS12730	COG1882	Formate acetyltransferase
SGLY_RS12735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGLY_RS12750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLY_RS12755	COG5012	cobalamin binding
SGLY_RS12760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLY_RS12775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLY_RS12790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS12820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SGLY_RS12840	COG0823	Involved in the tonB-independent uptake of proteins
SGLY_RS12840	COG1506	peptidase
SGLY_RS12840	COG4946	Tricorn protease homolog
SGLY_RS12845	COG4608	Belongs to the ABC transporter superfamily
SGLY_RS12850	COG0444	Belongs to the ABC transporter superfamily
SGLY_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
SGLY_RS12865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SGLY_RS12875	COG0747	negative chemotaxis
SGLY_RS12900	COG3620	sequence-specific DNA binding
SGLY_RS12910	COG0464	growth
SGLY_RS12925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SGLY_RS12930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SGLY_RS12940	COG4122	O-methyltransferase activity
SGLY_RS12945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SGLY_RS12945	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SGLY_RS12960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SGLY_RS12965	COG1846	Transcriptional regulator
SGLY_RS12970	COG5401	PFAM Sporulation and spore germination
SGLY_RS12980	COG0428	transporter
SGLY_RS13010	COG3409	Peptidoglycan-binding domain 1 protein
SGLY_RS13010	COG0793	Belongs to the peptidase S41A family
SGLY_RS13015	COG0628	permease
SGLY_RS13150	COG4397	Mu-like prophage major head subunit gpT
SGLY_RS13165	COG2369	cell adhesion
SGLY_RS13170	COG4383	Mu-like prophage protein gp29
SGLY_RS13290	COG0463	Glycosyl transferase, family 2
SGLY_RS13300	COG1360	Flagellar Motor Protein
SGLY_RS13305	COG2234	aminopeptidase activity
SGLY_RS13305	COG4935	Belongs to the peptidase S8 family
SGLY_RS13310	COG1728	Protein conserved in bacteria
SGLY_RS13315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SGLY_RS13325	COG1131	(ABC) transporter
SGLY_RS13365	COG0582	viral genome integration into host DNA
SGLY_RS13370	COG1476	TRANSCRIPTIONal
SGLY_RS13375	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SGLY_RS13400	COG0519	Catalyzes the synthesis of GMP from XMP
SGLY_RS13400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGLY_RS13405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SGLY_RS13415	COG0488	(ABC) transporter
SGLY_RS13435	COG0459	protein refolding
SGLY_RS13450	COG0347	Belongs to the P(II) protein family
SGLY_RS13470	COG1846	Transcriptional regulator
SGLY_RS13480	COG3383	formate dehydrogenase (NAD+) activity
SGLY_RS13495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SGLY_RS13500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SGLY_RS13505	COG0456	acetyltransferase
SGLY_RS13510	COG1214	PFAM Peptidase M22, glycoprotease
SGLY_RS13515	COG0802	atpase or kinase
SGLY_RS13520	COG1228	amidohydrolase
SGLY_RS13525	COG2337	Toxic component of a toxin-antitoxin (TA) module
SGLY_RS13545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SGLY_RS13560	COG0493	'glutamate synthase
SGLY_RS13565	COG0067	glutamate synthase
SGLY_RS13565	COG0070	glutamate synthase
SGLY_RS13565	COG0069	glutamate synthase activity
SGLY_RS13570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SGLY_RS13575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SGLY_RS13575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SGLY_RS13580	COG0736	holo-[acyl-carrier-protein] synthase activity
SGLY_RS13590	COG1509	lysine 2,3-aminomutase activity
SGLY_RS13595	COG1242	4 iron, 4 sulfur cluster binding
SGLY_RS13600	COG3300	MHYT domain
SGLY_RS13600	COG5001	Diguanylate cyclase
SGLY_RS13605	COG0004	ammonium transporteR
SGLY_RS13610	COG3885	ferrous iron binding
SGLY_RS13610	COG2078	PFAM AMMECR1 domain protein
SGLY_RS13630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGLY_RS13635	COG1027	Aspartate ammonia-lyase
SGLY_RS13640	COG1160	GTP binding
SGLY_RS13695	COG1012	belongs to the aldehyde dehydrogenase family
SGLY_RS13695	COG1454	alcohol dehydrogenase
SGLY_RS13715	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SGLY_RS13730	COG2814	Major facilitator Superfamily
SGLY_RS13775	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS13840	COG1132	(ABC) transporter
SGLY_RS13845	COG1132	(ABC) transporter
SGLY_RS13845	COG2375	cellular response to nickel ion
SGLY_RS13850	COG1309	transcriptional regulator
SGLY_RS13860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SGLY_RS13865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS13870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS13880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS13920	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS13925	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS13930	COG2197	response regulator
SGLY_RS13935	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS13945	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS13980	COG0626	cystathionine gamma-synthase activity
SGLY_RS13985	COG0626	cystathionine gamma-synthase activity
SGLY_RS14000	COG5012	cobalamin binding
SGLY_RS14005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SGLY_RS14010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SGLY_RS14020	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS14025	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS14035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGLY_RS14055	COG1132	(ABC) transporter
SGLY_RS14060	COG1132	(ABC) transporter
SGLY_RS14075	COG0840	transmembrane signaling receptor activity
SGLY_RS14085	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SGLY_RS14095	COG1464	Belongs to the NlpA lipoprotein family
SGLY_RS14100	COG2011	ABC-type metal ion transport system permease component
SGLY_RS14105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SGLY_RS14110	COG1433	Dinitrogenase iron-molybdenum cofactor
SGLY_RS14110	COG0535	radical SAM domain protein
SGLY_RS14115	COG0626	cystathionine gamma-synthase activity
SGLY_RS14125	COG0646	methionine synthase
SGLY_RS14125	COG1410	methionine synthase
SGLY_RS14130	COG1151	hydroxylamine reductase activity
SGLY_RS14135	COG0011	TIGRFAM Protein of
SGLY_RS14140	COG0326	Molecular chaperone. Has ATPase activity
SGLY_RS14150	COG0586	Pfam SNARE associated Golgi protein
SGLY_RS14160	COG4942	peptidase
SGLY_RS14170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SGLY_RS14200	COG1217	gtp-binding protein TYPA
SGLY_RS14210	COG1959	2 iron, 2 sulfur cluster binding
SGLY_RS14215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SGLY_RS14240	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
SGLY_RS14250	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS14255	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SGLY_RS14260	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SGLY_RS14265	COG0347	Belongs to the P(II) protein family
SGLY_RS14270	COG0347	Belongs to the P(II) protein family
SGLY_RS14305	COG0347	Belongs to the P(II) protein family
SGLY_RS14320	COG1910	domain protein
SGLY_RS14330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGLY_RS14335	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGLY_RS14340	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SGLY_RS14350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SGLY_RS14355	COG0583	DNA-binding transcription factor activity
SGLY_RS14370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SGLY_RS14370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SGLY_RS14395	COG0159	tryptophan synthase activity
SGLY_RS14405	COG0135	phosphoribosylanthranilate isomerase activity
SGLY_RS14410	COG0134	indole-3-glycerol-phosphate synthase activity
SGLY_RS14415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGLY_RS14420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SGLY_RS14420	COG0512	Glutamine amidotransferase of anthranilate synthase
SGLY_RS14450	COG1492	cobalamin metabolic process
SGLY_RS14460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SGLY_RS14465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SGLY_RS14470	COG1797	cobyrinic acid a,c-diamide synthase activity
SGLY_RS14485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SGLY_RS14490	COG0113	porphobilinogen synthase activity
SGLY_RS14520	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SGLY_RS14525	COG1122	ATPase activity
SGLY_RS14540	COG0310	cobalt ion transport
SGLY_RS14545	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SGLY_RS14555	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SGLY_RS14565	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SGLY_RS14575	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGLY_RS14580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SGLY_RS14595	COG1132	(ABC) transporter
SGLY_RS14635	COG0514	ATP-dependent DNA helicase (RecQ)
SGLY_RS14640	COG1132	(ABC) transporter
SGLY_RS14645	COG1994	Peptidase M50
SGLY_RS14650	COG0494	nUDIX hydrolase
SGLY_RS14665	COG0745	RESPONSE REGULATOR receiver
SGLY_RS14670	COG5002	protein histidine kinase activity
SGLY_RS14680	COG1131	(ABC) transporter
SGLY_RS14690	COG2814	Major facilitator Superfamily
SGLY_RS14695	COG0519	Catalyzes the synthesis of GMP from XMP
SGLY_RS14695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SGLY_RS14700	COG1074	ATP-dependent DNA helicase activity
SGLY_RS14705	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SGLY_RS14710	COG1733	regulation of RNA biosynthetic process
SGLY_RS14715	COG0655	NAD(P)H dehydrogenase (quinone) activity
SGLY_RS14720	COG0688	phosphatidylethanolamine metabolic process
SGLY_RS14725	COG5001	Diguanylate cyclase
SGLY_RS14725	COG3300	MHYT domain
SGLY_RS14730	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SGLY_RS14735	COG0577	efflux transmembrane transporter activity
SGLY_RS14735	COG1136	(ABC) transporter
SGLY_RS14865	COG4397	Mu-like prophage major head subunit gpT
SGLY_RS14880	COG2369	cell adhesion
SGLY_RS14885	COG4383	Mu-like prophage protein gp29
SGLY_RS15000	COG1309	transcriptional regulator
SGLY_RS15005	COG2247	cell wall binding repeat
SGLY_RS15005	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS15025	COG1404	Belongs to the peptidase S8 family
SGLY_RS15030	COG2247	cell wall binding repeat
SGLY_RS15030	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS15040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SGLY_RS15060	COG0438	transferase activity, transferring glycosyl groups
SGLY_RS15095	COG1086	Polysaccharide biosynthesis protein
SGLY_RS15105	COG2247	cell wall binding repeat
SGLY_RS15105	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS15110	COG2385	sporulation resulting in formation of a cellular spore
SGLY_RS15110	COG2247	cell wall binding repeat
SGLY_RS15125	COG0640	Transcriptional regulator
SGLY_RS15150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SGLY_RS15155	COG0740	serine-type endopeptidase activity
SGLY_RS15160	COG1620	l-lactate permease
SGLY_RS15165	COG1620	l-lactate permease
SGLY_RS15175	COG0825	malonyl-CoA metabolic process
SGLY_RS15175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGLY_RS15180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SGLY_RS15185	COG0439	Biotin carboxylase
SGLY_RS15190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SGLY_RS15195	COG0511	ligase activity, forming carbon-carbon bonds
SGLY_RS15200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SGLY_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
SGLY_RS15210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SGLY_RS15215	COG2070	2-Nitropropane dioxygenase
SGLY_RS15220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SGLY_RS15225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SGLY_RS15235	COG0531	amino acid
SGLY_RS15255	COG1592	Rubrerythrin
SGLY_RS15260	COG2033	superoxide reductase activity
SGLY_RS15265	COG0426	domain, Protein
SGLY_RS15270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SGLY_RS15270	COG1773	rubredoxin
SGLY_RS15285	COG0513	Belongs to the DEAD box helicase family
SGLY_RS15290	COG0583	DNA-binding transcription factor activity
SGLY_RS15295	COG2807	transmembrane transport
SGLY_RS15300	COG0589	response to stress
SGLY_RS15330	COG1846	Transcriptional regulator
SGLY_RS15345	COG1346	cytolysis
SGLY_RS15350	COG1380	Effector of murein hydrolase LrgA
SGLY_RS15360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SGLY_RS15365	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SGLY_RS15380	COG4632	Exopolysaccharide biosynthesis protein
SGLY_RS15380	COG5434	Belongs to the glycosyl hydrolase 28 family
SGLY_RS15390	COG3973	AAA domain
SGLY_RS15395	COG1388	LysM domain
SGLY_RS15395	COG3942	CHAP domain
SGLY_RS15400	COG2827	Endonuclease containing a URI domain
SGLY_RS15420	COG0521	Mo-molybdopterin cofactor biosynthetic process
SGLY_RS15425	COG0315	cyclic pyranopterin monophosphate synthase activity
SGLY_RS15430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SGLY_RS15435	COG0303	'Molybdopterin
SGLY_RS15465	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SGLY_RS15470	COG1122	ATPase activity
SGLY_RS15475	COG1122	ATPase activity
SGLY_RS15485	COG1929	Belongs to the glycerate kinase type-1 family
SGLY_RS15490	COG2084	Dehydrogenase
SGLY_RS15495	COG3622	Belongs to the hyi family
SGLY_RS15500	COG3960	tartronate-semialdehyde synthase activity
SGLY_RS15505	COG0588	phosphoglycerate mutase activity
SGLY_RS15510	COG2814	Major facilitator Superfamily
SGLY_RS15535	COG1120	ATPase activity
SGLY_RS15540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SGLY_RS15545	COG1720	tRNA m6t6A37 methyltransferase activity
SGLY_RS15555	COG0444	Belongs to the ABC transporter superfamily
SGLY_RS15565	COG4129	membrane
SGLY_RS15570	COG0586	Pfam SNARE associated Golgi protein
SGLY_RS15575	COG1283	sodium-dependent phosphate transmembrane transporter activity
SGLY_RS15580	COG0602	queuosine metabolic process
SGLY_RS15585	COG0720	synthase
SGLY_RS15590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SGLY_RS15595	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SGLY_RS15730	COG4397	Mu-like prophage major head subunit gpT
SGLY_RS15745	COG2369	cell adhesion
SGLY_RS15750	COG4383	Mu-like prophage protein gp29
SGLY_RS15845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SGLY_RS15845	COG2199	diguanylate cyclase activity
SGLY_RS15855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SGLY_RS15875	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SGLY_RS15880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SGLY_RS15890	COG5002	protein histidine kinase activity
SGLY_RS15895	COG0745	RESPONSE REGULATOR receiver
SGLY_RS15905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SGLY_RS15910	COG1982	Orn Lys Arg decarboxylase major
SGLY_RS15935	COG0582	viral genome integration into host DNA
SGLY_RS15940	COG1194	a g-specific adenine glycosylase
SGLY_RS15945	COG3585	molybdate ion transport
SGLY_RS15950	COG2267	carboxylic ester hydrolase activity
SGLY_RS15975	COG2378	regulation of single-species biofilm formation
SGLY_RS15995	COG0586	Pfam SNARE associated Golgi protein
SGLY_RS16000	COG0589	response to stress
SGLY_RS16005	COG0861	Integral membrane protein TerC family
SGLY_RS16060	COG2226	methyltransferase
SGLY_RS16065	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SGLY_RS16070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SGLY_RS16075	COG0148	phosphopyruvate hydratase activity
SGLY_RS16085	COG0149	triose-phosphate isomerase activity
SGLY_RS16090	COG0126	phosphoglycerate kinase activity
SGLY_RS16095	COG1283	sodium-dependent phosphate transmembrane transporter activity
SGLY_RS16105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SGLY_RS16125	COG0561	phosphatase activity
SGLY_RS16140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SGLY_RS16145	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SGLY_RS16190	COG2949	membrane
SGLY_RS16195	COG0024	Methionine aminopeptidase
SGLY_RS16210	COG1329	Transcriptional regulator
SGLY_RS16220	COG1162	GTPase activity
SGLY_RS16225	COG0288	reversible hydration of carbon dioxide
SGLY_RS16230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SGLY_RS16235	COG0556	nucleotide-excision repair
SGLY_RS16245	COG3409	Peptidoglycan-binding domain 1 protein
SGLY_RS16245	COG0793	Belongs to the peptidase S41A family
SGLY_RS16250	COG0741	lytic transglycosylase activity
SGLY_RS16250	COG1196	nuclear chromosome segregation
SGLY_RS16250	COG0739	heme binding
SGLY_RS16255	COG2177	Part of the ABC transporter FtsEX involved in
SGLY_RS16260	COG2884	Cell division ATP-binding protein ftsE
SGLY_RS16265	COG3958	Transketolase
SGLY_RS16270	COG3959	Transketolase, thiamine diphosphate binding domain
SGLY_RS16275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SGLY_RS16290	COG0653	protein targeting
SGLY_RS16295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SGLY_RS16305	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SGLY_RS16320	COG0438	transferase activity, transferring glycosyl groups
SGLY_RS16330	COG1077	Cell shape determining protein MreB Mrl
SGLY_RS16335	COG1609	Transcriptional regulator
SGLY_RS16340	COG2385	sporulation resulting in formation of a cellular spore
SGLY_RS16345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SGLY_RS16380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SGLY_RS16385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SGLY_RS16390	COG0356	it plays a direct role in the translocation of protons across the membrane
SGLY_RS16405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SGLY_RS16420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SGLY_RS16425	COG0698	ribose 5-phosphate isomerase
SGLY_RS16435	COG1971	Probably functions as a manganese efflux pump
SGLY_RS16440	COG0009	L-threonylcarbamoyladenylate synthase
SGLY_RS16445	COG2890	protein-(glutamine-N5) methyltransferase activity
SGLY_RS16450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SGLY_RS16455	COG3872	metal-dependent enzyme
SGLY_RS16465	COG1494	fructose-1,6-bisphosphatase
SGLY_RS16485	COG2204	response regulator
SGLY_RS16490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SGLY_RS16495	COG2348	transferase activity, transferring amino-acyl groups
SGLY_RS16500	COG0504	CTP synthase activity
SGLY_RS16510	COG2959	enzyme of heme biosynthesis
SGLY_RS16520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SGLY_RS16530	COG0116	Belongs to the methyltransferase superfamily
SGLY_RS16535	COG0745	RESPONSE REGULATOR receiver
SGLY_RS16550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SGLY_RS16555	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SGLY_RS16565	COG2119	membrane
SGLY_RS16575	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SGLY_RS16580	COG2188	Transcriptional regulator
SGLY_RS16585	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SGLY_RS16590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SGLY_RS16605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SGLY_RS16610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SGLY_RS16615	COG3383	formate dehydrogenase (NAD+) activity
SGLY_RS16650	COG1122	ATPase activity
SGLY_RS16675	COG1131	(ABC) transporter
SGLY_RS16685	COG2197	response regulator
SGLY_RS16690	COG4585	Histidine kinase
SGLY_RS16695	COG1442	glycosyl transferase family 8
SGLY_RS16695	COG1216	Glycosyl transferase, family 2
SGLY_RS16710	COG1131	(ABC) transporter
SGLY_RS16725	COG0772	Belongs to the SEDS family
SGLY_RS16730	COG1695	Transcriptional regulator
SGLY_RS16740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SGLY_RS16745	COG0305	Participates in initiation and elongation during chromosome replication
SGLY_RS16750	COG0470	DNA polymerase III
SGLY_RS16750	COG1067	ATP-dependent peptidase activity
SGLY_RS16770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SGLY_RS16775	COG0629	single-stranded DNA binding
SGLY_RS16785	COG0012	GTP binding
SGLY_RS16800	COG0683	leucine binding
SGLY_RS16810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SGLY_RS16825	COG1475	DNA binding
SGLY_RS16830	COG1192	Involved in chromosome partitioning
SGLY_RS16835	COG0357	Ribosomal RNA small subunit methyltransferase G
SGLY_RS16840	COG0445	tRNA wobble uridine modification
SGLY_RS16845	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SGLY_RS16850	COG1847	R3H domain protein
SGLY_RS16855	COG0706	membrane insertase activity
SGLY_RS16860	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SGLY_RS16865	COG0594	ribonuclease P activity
SGLY_RS16885	COG0582	viral genome integration into host DNA
SGLY_RS16900	COG0456	acetyltransferase
SGLY_RS16915	COG3773	Cell wall hydrolase
SGLY_RS16930	COG2226	methyltransferase
SGLY_RS16965	COG3328	transposase activity
SGLY_RS17000	COG1482	cell wall glycoprotein biosynthetic process
SGLY_RS17005	COG1482	cell wall glycoprotein biosynthetic process
SGLY_RS17035	COG2385	sporulation resulting in formation of a cellular spore
SGLY_RS17035	COG2247	cell wall binding repeat
SGLY_RS17075	COG1129	ABC transporter
SGLY_RS17110	COG2247	cell wall binding repeat
SGLY_RS17110	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS17115	COG5039	Polysaccharide pyruvyl transferase
SGLY_RS17135	COG2608	mercury ion transmembrane transporter activity
SGLY_RS17170	COG2247	cell wall binding repeat
SGLY_RS17170	COG0860	N-Acetylmuramoyl-L-alanine amidase
SGLY_RS17175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SGLY_RS17185	COG3773	Cell wall hydrolase
SGLY_RS17185	COG3409	Peptidoglycan-binding domain 1 protein
SGLY_RS17235	COG2247	cell wall binding repeat
SGLY_RS17235	COG2385	sporulation resulting in formation of a cellular spore
SGLY_RS17245	COG0840	transmembrane signaling receptor activity
SGLY_RS17285	COG3852	Histidine kinase