locus-tag	class	description
FBF28_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FBF28_RS00010	COG0592	DNA-directed DNA polymerase activity
FBF28_RS00105	COG0071	Belongs to the small heat shock protein (HSP20) family
FBF28_RS00115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FBF28_RS00160	COG0525	valine-tRNA ligase activity
FBF28_RS00170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FBF28_RS00185	COG1470	cell adhesion involved in biofilm formation
FBF28_RS00185	COG0366	Alpha amylase catalytic
FBF28_RS00215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF28_RS00225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FBF28_RS00230	COG0459	protein refolding
FBF28_RS00240	COG2222	sugar isomerase
FBF28_RS00245	COG0577	efflux transmembrane transporter activity
FBF28_RS00250	COG1136	(ABC) transporter
FBF28_RS00270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF28_RS00295	COG0018	arginyl-trna synthetase
FBF28_RS00310	COG0528	UMP kinase activity
FBF28_RS00320	COG2315	Protein conserved in bacteria
FBF28_RS00330	COG0358	DNA primase activity
FBF28_RS00335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FBF28_RS00345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF28_RS00345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF28_RS00355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FBF28_RS00380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FBF28_RS00390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FBF28_RS00410	COG1185	polyribonucleotide nucleotidyltransferase activity
FBF28_RS00420	COG1573	uracil-dna glycosylase
FBF28_RS00425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FBF28_RS00445	COG0360	Binds together with S18 to 16S ribosomal RNA
FBF28_RS00450	COG0629	single-stranded DNA binding
FBF28_RS00455	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FBF28_RS00460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FBF28_RS00465	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FBF28_RS00510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FBF28_RS00525	COG4969	Belongs to the N-Me-Phe pilin family
FBF28_RS00555	COG4974	Belongs to the 'phage' integrase family
FBF28_RS00600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FBF28_RS00610	COG3695	enzyme binding
FBF28_RS00615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FBF28_RS00630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FBF28_RS00635	COG1994	Peptidase M50
FBF28_RS00645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FBF28_RS00650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FBF28_RS00695	COG0187	DNA topoisomerase II activity
FBF28_RS00700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF28_RS00735	COG0167	dihydroorotate dehydrogenase activity
FBF28_RS00765	COG1940	carbohydrate kinase activity
FBF28_RS00775	COG0539	negative regulation of cytoplasmic translation
FBF28_RS00780	COG3170	Tfp pilus assembly protein FimV
FBF28_RS00780	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FBF28_RS00800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FBF28_RS00805	COG0242	peptide deformylase activity
FBF28_RS00810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FBF28_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FBF28_RS00820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FBF28_RS00835	COG1610	YqeY-like protein
FBF28_RS00840	COG0563	adenylate kinase activity
FBF28_RS00855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FBF28_RS00860	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FBF28_RS00895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FBF28_RS00915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FBF28_RS00920	COG1192	Involved in chromosome partitioning
FBF28_RS00925	COG1475	DNA binding
FBF28_RS00945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF28_RS00950	COG2890	protein-(glutamine-N5) methyltransferase activity
FBF28_RS00960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FBF28_RS00970	COG0254	rRNA binding
FBF28_RS00980	COG0052	Belongs to the universal ribosomal protein uS2 family
FBF28_RS00985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FBF28_RS01000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FBF28_RS01010	COG0233	cytoplasmic translational termination
FBF28_RS01020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FBF28_RS01035	COG0442	prolyl-tRNA aminoacylation
FBF28_RS01055	COG4536	flavin adenine dinucleotide binding
FBF28_RS01060	COG0577	efflux transmembrane transporter activity
FBF28_RS01060	COG1136	(ABC) transporter
FBF28_RS01065	COG1136	(ABC) transporter
FBF28_RS01070	COG1695	Transcriptional regulator
FBF28_RS01080	COG1968	undecaprenyl-diphosphatase activity
FBF28_RS01085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FBF28_RS01090	COG0577	efflux transmembrane transporter activity
FBF28_RS01105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FBF28_RS01115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FBF28_RS01120	COG0653	protein targeting
FBF28_RS01135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FBF28_RS01155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FBF28_RS01165	COG2884	Cell division ATP-binding protein ftsE
FBF28_RS01170	COG2177	Part of the ABC transporter FtsEX involved in
FBF28_RS01175	COG3942	CHAP domain
FBF28_RS01180	COG0793	Belongs to the peptidase S41A family
FBF28_RS01185	COG0745	RESPONSE REGULATOR receiver
FBF28_RS01190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FBF28_RS01210	COG1570	exodeoxyribonuclease VII activity
FBF28_RS01220	COG2264	protein methyltransferase activity
FBF28_RS01230	COG2205	protein histidine kinase activity
FBF28_RS01240	COG1381	Involved in DNA repair and RecF pathway recombination
FBF28_RS01250	COG0423	glycine-tRNA ligase activity
FBF28_RS01305	COG0019	diaminopimelate decarboxylase activity
FBF28_RS01315	COG0328	RNA-DNA hybrid ribonuclease activity
FBF28_RS01325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FBF28_RS01330	COG2723	6-phospho-beta-galactosidase activity
FBF28_RS01335	COG2001	Belongs to the MraZ family
FBF28_RS01340	COG0275	rRNA processing
FBF28_RS01355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FBF28_RS01360	COG0772	Belongs to the SEDS family
FBF28_RS01365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FBF28_RS01415	COG0758	DNA mediated transformation
FBF28_RS01440	COG0701	Predicted permease
FBF28_RS01475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FBF28_RS01495	COG1051	belongs to the nudix hydrolase family
FBF28_RS01500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FBF28_RS01505	COG1136	(ABC) transporter
FBF28_RS01560	COG0456	acetyltransferase
FBF28_RS01560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FBF28_RS01565	COG5002	protein histidine kinase activity
FBF28_RS01570	COG0745	RESPONSE REGULATOR receiver
FBF28_RS01575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FBF28_RS01580	COG5002	protein histidine kinase activity
FBF28_RS01585	COG0745	RESPONSE REGULATOR receiver
FBF28_RS01595	COG4152	abc transporter atp-binding protein
FBF28_RS01610	COG0215	cysteine-tRNA ligase activity
FBF28_RS01625	COG1160	GTP binding
FBF28_RS01635	COG1187	pseudouridine synthase activity
FBF28_RS01640	COG0745	RESPONSE REGULATOR receiver
FBF28_RS01645	COG5002	protein histidine kinase activity
FBF28_RS01655	COG0577	efflux transmembrane transporter activity
FBF28_RS01655	COG1136	(ABC) transporter
FBF28_RS01660	COG0456	acetyltransferase
FBF28_RS01750	COG1136	(ABC) transporter
FBF28_RS01780	COG0745	RESPONSE REGULATOR receiver
FBF28_RS01785	COG5002	protein histidine kinase activity
FBF28_RS01790	COG1470	cell adhesion involved in biofilm formation
FBF28_RS01795	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FBF28_RS01795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FBF28_RS01835	COG1876	peptidase activity
FBF28_RS01840	COG1876	peptidase activity
FBF28_RS01845	COG0708	Exodeoxyribonuclease III
FBF28_RS01850	COG0297	glycogen (starch) synthase activity
FBF28_RS01850	COG0438	transferase activity, transferring glycosyl groups
FBF28_RS01860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FBF28_RS01875	COG0488	(ABC) transporter
FBF28_RS01915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FBF28_RS01920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FBF28_RS01930	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FBF28_RS01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FBF28_RS01945	COG3177	Filamentation induced by cAMP protein fic
FBF28_RS01980	COG1136	(ABC) transporter
FBF28_RS01985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FBF28_RS01990	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FBF28_RS02000	COG0305	Participates in initiation and elongation during chromosome replication
FBF28_RS02005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FBF28_RS02020	COG0222	ribosome binding
FBF28_RS02025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FBF28_RS02030	COG0081	regulation of translation
FBF28_RS02040	COG0148	phosphopyruvate hydratase activity
FBF28_RS02045	COG0009	L-threonylcarbamoyladenylate synthase
FBF28_RS02050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FBF28_RS02060	COG0250	Participates in transcription elongation, termination and antitermination
FBF28_RS02070	COG5002	protein histidine kinase activity
FBF28_RS02160	COG0470	DNA polymerase III
FBF28_RS02165	COG0564	pseudouridine synthase activity
FBF28_RS02170	COG0180	Tryptophanyl-tRNA synthetase
FBF28_RS02185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FBF28_RS02190	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FBF28_RS02195	COG0203	ribosomal protein L17
FBF28_RS02200	COG0202	RNA polymerase activity
FBF28_RS02205	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FBF28_RS02210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FBF28_RS02220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FBF28_RS02225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FBF28_RS02240	COG0200	Binds to the 23S rRNA
FBF28_RS02245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FBF28_RS02255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FBF28_RS02260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FBF28_RS02270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FBF28_RS02275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FBF28_RS02280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FBF28_RS02285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FBF28_RS02290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FBF28_RS02295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FBF28_RS02300	COG0255	Belongs to the universal ribosomal protein uL29 family
FBF28_RS02305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FBF28_RS02310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FBF28_RS02315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FBF28_RS02320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FBF28_RS02325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FBF28_RS02330	COG0089	rRNA binding
FBF28_RS02335	COG0088	Forms part of the polypeptide exit tunnel
FBF28_RS02340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FBF28_RS02350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FBF28_RS02360	COG1666	GTP binding
FBF28_RS02365	COG0049	tRNA binding
FBF28_RS02370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FBF28_RS02375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FBF28_RS02380	COG0085	RNA polymerase activity
FBF28_RS02390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FBF28_RS02410	COG0740	serine-type endopeptidase activity
FBF28_RS02460	COG0277	FAD linked oxidase domain protein
FBF28_RS02480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FBF28_RS02495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FBF28_RS02505	COG1181	Belongs to the D-alanine--D-alanine ligase family
FBF28_RS02510	COG0330	HflC and HflK could
FBF28_RS02515	COG2267	carboxylic ester hydrolase activity
FBF28_RS02560	COG2988	succinylglutamate desuccinylase activity
FBF28_RS02575	COG0366	Alpha amylase catalytic
FBF28_RS02585	COG0742	ribosomal rna small subunit methyltransferase
FBF28_RS02595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FBF28_RS02605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FBF28_RS02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF28_RS02615	COG4956	integral membrane protein (PIN domain superfamily)
FBF28_RS02620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FBF28_RS02635	COG0195	Participates in both transcription termination and antitermination
FBF28_RS02660	COG0492	ferredoxin-NADP+ reductase activity
FBF28_RS02670	COG1132	(ABC) transporter
FBF28_RS02675	COG0072	phenylalanine-tRNA ligase activity
FBF28_RS02675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF28_RS02730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FBF28_RS02765	COG0336	Belongs to the RNA methyltransferase TrmD family
FBF28_RS02770	COG1837	Belongs to the UPF0109 family
FBF28_RS02775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FBF28_RS02780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FBF28_RS02790	COG0849	cell division
FBF28_RS02800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FBF28_RS02810	COG0228	four-way junction DNA binding
FBF28_RS02835	COG0613	PHP domain protein
FBF28_RS02850	COG1104	cysteine desulfurase activity
FBF28_RS02865	COG0084	hydrolase, TatD family'
FBF28_RS02870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF28_RS02920	COG0149	triose-phosphate isomerase activity
FBF28_RS02925	COG0126	phosphoglycerate kinase activity
FBF28_RS02930	COG0469	pyruvate kinase activity
FBF28_RS02935	COG0571	ribonuclease III activity
FBF28_RS02960	COG0495	leucyl-tRNA aminoacylation
FBF28_RS02970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF28_RS02980	COG0280	phosphate acetyltransferase
FBF28_RS02995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FBF28_RS03005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FBF28_RS03015	COG0501	Belongs to the peptidase M48B family
FBF28_RS03020	COG1704	LemA family
FBF28_RS03030	COG1131	(ABC) transporter
FBF28_RS03040	COG3613	nucleoside 2-deoxyribosyltransferase
FBF28_RS03050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FBF28_RS03055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FBF28_RS03060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FBF28_RS03065	COG0302	gtp cyclohydrolase
FBF28_RS03120	COG1950	PFAM Membrane protein of
FBF28_RS03130	COG0322	excinuclease ABC activity
FBF28_RS03160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FBF28_RS03170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FBF28_RS03180	COG0154	amidase activity
FBF28_RS03200	COG0556	nucleotide-excision repair
FBF28_RS03205	COG1611	Belongs to the LOG family
FBF28_RS03215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FBF28_RS03220	COG0191	fructose-bisphosphate aldolase activity
FBF28_RS03225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FBF28_RS03230	COG3959	Transketolase, thiamine diphosphate binding domain
FBF28_RS03240	COG0698	ribose 5-phosphate isomerase
FBF28_RS03260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FBF28_RS03270	COG0335	large ribosomal subunit rRNA binding
FBF28_RS03275	COG0281	malic enzyme
FBF28_RS03280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FBF28_RS03300	COG0051	transcription antitermination factor activity, RNA binding
FBF28_RS03325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FBF28_RS03330	COG0343	queuine tRNA-ribosyltransferase activity
FBF28_RS03340	COG1573	uracil-dna glycosylase
FBF28_RS03370	COG1132	(ABC) transporter
FBF28_RS03375	COG0586	Pfam SNARE associated Golgi protein
FBF28_RS03380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FBF28_RS03400	COG1136	(ABC) transporter
FBF28_RS03415	COG2925	Exonuclease
FBF28_RS03420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FBF28_RS03425	COG3942	CHAP domain
FBF28_RS03425	COG1388	LysM domain
FBF28_RS03455	COG5002	protein histidine kinase activity
FBF28_RS03465	COG2204	response regulator
FBF28_RS03470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FBF28_RS03505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FBF28_RS03510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FBF28_RS03535	COG4968	Prepilin-type N-terminal cleavage methylation domain
FBF28_RS03540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FBF28_RS03560	COG0542	response to heat
FBF28_RS03615	COG0588	phosphoglycerate mutase activity
FBF28_RS03620	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FBF28_RS03625	COG1418	mRNA catabolic process
FBF28_RS03630	COG1214	PFAM Peptidase M22, glycoprotease
FBF28_RS03635	COG0802	atpase or kinase
FBF28_RS03665	COG1459	type II secretion system
FBF28_RS03685	COG0572	uridine kinase
FBF28_RS03690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FBF28_RS03695	COG0668	transmembrane transport
FBF28_RS03720	COG1194	a g-specific adenine glycosylase
FBF28_RS03735	COG0494	nUDIX hydrolase
FBF28_RS03740	COG0300	oxidoreductase activity
FBF28_RS03750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FBF28_RS03755	COG2255	four-way junction helicase activity
FBF28_RS03770	COG0632	four-way junction helicase activity
FBF28_RS03775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF28_RS03780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FBF28_RS03795	COG0217	transcriptional regulatory protein
FBF28_RS03825	COG0189	ligase activity
FBF28_RS03870	COG0443	Heat shock 70 kDa protein
FBF28_RS03875	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FBF28_RS03895	COG0194	GDP metabolic process
FBF28_RS03915	COG0481	GTPase activity
FBF28_RS03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF28_RS03945	COG0037	tRNA processing
FBF28_RS03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FBF28_RS03980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FBF28_RS03985	COG1365	unkown
FBF28_RS03990	COG1324	tolerance protein
FBF28_RS04070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FBF28_RS04075	COG2137	regulation of response to DNA damage stimulus
FBF28_RS04085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FBF28_RS04105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FBF28_RS04105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FBF28_RS04115	COG0477	Major facilitator Superfamily
FBF28_RS04130	COG1131	(ABC) transporter
FBF28_RS04155	COG1288	antiporter activity
FBF28_RS04160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FBF28_RS04195	COG1204	response to ionizing radiation
FBF28_RS04205	COG1132	(ABC) transporter
FBF28_RS04220	COG0494	nUDIX hydrolase
FBF28_RS04245	COG0765	amino acid transport
FBF28_RS04250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF28_RS04260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FBF28_RS04275	COG0542	response to heat
FBF28_RS04285	COG1136	(ABC) transporter
FBF28_RS04305	COG0726	polysaccharide deacetylase
FBF28_RS04310	COG1872	DUF167
FBF28_RS04315	COG3620	sequence-specific DNA binding
FBF28_RS04345	COG2003	Belongs to the UPF0758 family
FBF28_RS04370	COG1328	CTP reductase activity
FBF28_RS04370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FBF28_RS04385	COG1131	(ABC) transporter
FBF28_RS04390	COG3850	Histidine kinase
FBF28_RS04390	COG5002	protein histidine kinase activity
FBF28_RS04395	COG5002	protein histidine kinase activity
FBF28_RS04405	COG1619	proteins homologs of microcin C7 resistance protein MccF
FBF28_RS04415	COG1619	proteins homologs of microcin C7 resistance protein MccF
FBF28_RS04445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FBF28_RS04535	COG1215	transferase activity, transferring glycosyl groups
FBF28_RS04585	COG0297	glycogen (starch) synthase activity
FBF28_RS04590	COG0438	transferase activity, transferring glycosyl groups
FBF28_RS04610	COG0594	ribonuclease P activity
FBF28_RS04615	COG0230	Belongs to the bacterial ribosomal protein bL34 family