locus-tag	class	description
FBF26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FBF26_RS00010	COG0592	DNA-directed DNA polymerase activity
FBF26_RS00105	COG0071	Belongs to the small heat shock protein (HSP20) family
FBF26_RS00115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FBF26_RS00160	COG0525	valine-tRNA ligase activity
FBF26_RS00170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FBF26_RS00210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF26_RS00225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FBF26_RS00230	COG0459	protein refolding
FBF26_RS00245	COG2222	sugar isomerase
FBF26_RS00250	COG0577	efflux transmembrane transporter activity
FBF26_RS00255	COG1136	(ABC) transporter
FBF26_RS00280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FBF26_RS00310	COG0504	CTP synthase activity
FBF26_RS00320	COG0018	arginyl-trna synthetase
FBF26_RS00335	COG0528	UMP kinase activity
FBF26_RS00350	COG2315	Protein conserved in bacteria
FBF26_RS00360	COG0358	DNA primase activity
FBF26_RS00365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FBF26_RS00375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF26_RS00375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FBF26_RS00390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FBF26_RS00415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FBF26_RS00425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FBF26_RS00450	COG1185	polyribonucleotide nucleotidyltransferase activity
FBF26_RS00460	COG1573	uracil-dna glycosylase
FBF26_RS00465	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FBF26_RS00490	COG0360	Binds together with S18 to 16S ribosomal RNA
FBF26_RS00495	COG0629	single-stranded DNA binding
FBF26_RS00500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FBF26_RS00505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FBF26_RS00510	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FBF26_RS00555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FBF26_RS00570	COG4969	Belongs to the N-Me-Phe pilin family
FBF26_RS00600	COG4974	Belongs to the 'phage' integrase family
FBF26_RS00645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FBF26_RS00655	COG3695	enzyme binding
FBF26_RS00660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FBF26_RS00675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FBF26_RS00680	COG1994	Peptidase M50
FBF26_RS00690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FBF26_RS00695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FBF26_RS00740	COG0187	DNA topoisomerase II activity
FBF26_RS00745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FBF26_RS00785	COG0167	dihydroorotate dehydrogenase activity
FBF26_RS00825	COG0539	negative regulation of cytoplasmic translation
FBF26_RS00830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FBF26_RS00830	COG3170	Tfp pilus assembly protein FimV
FBF26_RS00845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FBF26_RS00850	COG0242	peptide deformylase activity
FBF26_RS00855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FBF26_RS00865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FBF26_RS00865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FBF26_RS00880	COG1610	YqeY-like protein
FBF26_RS00885	COG0563	adenylate kinase activity
FBF26_RS00905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FBF26_RS00945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FBF26_RS00945	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FBF26_RS00950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FBF26_RS00970	COG1192	Involved in chromosome partitioning
FBF26_RS00975	COG1475	DNA binding
FBF26_RS00995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FBF26_RS01000	COG2890	protein-(glutamine-N5) methyltransferase activity
FBF26_RS01010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FBF26_RS01020	COG0254	rRNA binding
FBF26_RS01030	COG0052	Belongs to the universal ribosomal protein uS2 family
FBF26_RS01035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FBF26_RS01050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FBF26_RS01060	COG0233	cytoplasmic translational termination
FBF26_RS01070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FBF26_RS01075	COG0750	zinc metalloprotease
FBF26_RS01085	COG0442	prolyl-tRNA aminoacylation
FBF26_RS01105	COG4535	Mg2 and Co2 transporter CorC
FBF26_RS01115	COG1136	(ABC) transporter
FBF26_RS01115	COG0577	efflux transmembrane transporter activity
FBF26_RS01120	COG1136	(ABC) transporter
FBF26_RS01125	COG1695	Transcriptional regulator
FBF26_RS01135	COG1968	undecaprenyl-diphosphatase activity
FBF26_RS01140	COG1136	(ABC) transporter
FBF26_RS01145	COG0577	efflux transmembrane transporter activity
FBF26_RS01155	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FBF26_RS01160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FBF26_RS01165	COG0653	protein targeting
FBF26_RS01175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FBF26_RS01185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FBF26_RS01190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FBF26_RS01195	COG2884	Cell division ATP-binding protein ftsE
FBF26_RS01200	COG2177	Part of the ABC transporter FtsEX involved in
FBF26_RS01210	COG0793	Belongs to the peptidase S41A family
FBF26_RS01215	COG0745	RESPONSE REGULATOR receiver
FBF26_RS01240	COG1570	exodeoxyribonuclease VII activity
FBF26_RS01250	COG2264	protein methyltransferase activity
FBF26_RS01260	COG5002	protein histidine kinase activity
FBF26_RS01270	COG1381	Involved in DNA repair and RecF pathway recombination
FBF26_RS01280	COG0423	glycine-tRNA ligase activity
FBF26_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
FBF26_RS01320	COG0019	diaminopimelate decarboxylase activity
FBF26_RS01330	COG0328	RNA-DNA hybrid ribonuclease activity
FBF26_RS01340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FBF26_RS01345	COG2723	6-phospho-beta-galactosidase activity
FBF26_RS01350	COG2001	Belongs to the MraZ family
FBF26_RS01355	COG0275	rRNA processing
FBF26_RS01370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FBF26_RS01375	COG0772	Belongs to the SEDS family
FBF26_RS01380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FBF26_RS01420	COG4974	Belongs to the 'phage' integrase family
FBF26_RS01495	COG1525	nuclease
FBF26_RS01655	COG0758	DNA mediated transformation
FBF26_RS01680	COG0701	Predicted permease
FBF26_RS01710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FBF26_RS01725	COG1051	belongs to the nudix hydrolase family
FBF26_RS01735	COG1136	(ABC) transporter
FBF26_RS01780	COG0105	UTP biosynthetic process
FBF26_RS01785	COG0302	gtp cyclohydrolase
FBF26_RS01820	COG0456	acetyltransferase
FBF26_RS01820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FBF26_RS01825	COG5002	protein histidine kinase activity
FBF26_RS01830	COG0745	RESPONSE REGULATOR receiver
FBF26_RS01835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FBF26_RS01840	COG5002	protein histidine kinase activity
FBF26_RS01845	COG0745	RESPONSE REGULATOR receiver
FBF26_RS01855	COG4152	abc transporter atp-binding protein
FBF26_RS01870	COG0215	cysteine-tRNA ligase activity
FBF26_RS01895	COG1160	GTP binding
FBF26_RS01910	COG1187	pseudouridine synthase activity
FBF26_RS01915	COG0745	RESPONSE REGULATOR receiver
FBF26_RS01920	COG5002	protein histidine kinase activity
FBF26_RS01930	COG0577	efflux transmembrane transporter activity
FBF26_RS01930	COG1136	(ABC) transporter
FBF26_RS01935	COG0456	acetyltransferase
FBF26_RS01970	COG0745	RESPONSE REGULATOR receiver
FBF26_RS01975	COG5002	protein histidine kinase activity
FBF26_RS01980	COG1470	cell adhesion involved in biofilm formation
FBF26_RS01985	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FBF26_RS01985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FBF26_RS02025	COG1876	peptidase activity
FBF26_RS02030	COG1876	peptidase activity
FBF26_RS02035	COG0708	Exodeoxyribonuclease III
FBF26_RS02040	COG0297	glycogen (starch) synthase activity
FBF26_RS02040	COG0438	transferase activity, transferring glycosyl groups
FBF26_RS02050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FBF26_RS02065	COG0488	(ABC) transporter
FBF26_RS02105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FBF26_RS02110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FBF26_RS02120	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FBF26_RS02130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FBF26_RS02135	COG3177	Filamentation induced by cAMP protein fic
FBF26_RS02170	COG1136	(ABC) transporter
FBF26_RS02175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FBF26_RS02180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FBF26_RS02190	COG0305	Participates in initiation and elongation during chromosome replication
FBF26_RS02195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FBF26_RS02210	COG0222	ribosome binding
FBF26_RS02215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FBF26_RS02220	COG0081	regulation of translation
FBF26_RS02235	COG0148	phosphopyruvate hydratase activity
FBF26_RS02240	COG0009	L-threonylcarbamoyladenylate synthase
FBF26_RS02245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FBF26_RS02255	COG0250	Participates in transcription elongation, termination and antitermination
FBF26_RS02265	COG5002	protein histidine kinase activity
FBF26_RS02305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FBF26_RS02375	COG0470	DNA polymerase III
FBF26_RS02380	COG0564	pseudouridine synthase activity
FBF26_RS02385	COG0180	Tryptophanyl-tRNA synthetase
FBF26_RS02395	COG0596	Alpha beta hydrolase
FBF26_RS02405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FBF26_RS02410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FBF26_RS02415	COG0203	ribosomal protein L17
FBF26_RS02420	COG0202	RNA polymerase activity
FBF26_RS02425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FBF26_RS02430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FBF26_RS02440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FBF26_RS02445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FBF26_RS02460	COG0200	Binds to the 23S rRNA
FBF26_RS02465	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FBF26_RS02470	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FBF26_RS02475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FBF26_RS02500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FBF26_RS02505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FBF26_RS02515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FBF26_RS02520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FBF26_RS02525	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FBF26_RS02530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FBF26_RS02535	COG0255	Belongs to the universal ribosomal protein uL29 family
FBF26_RS02540	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FBF26_RS02545	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FBF26_RS02550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FBF26_RS02555	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FBF26_RS02560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FBF26_RS02565	COG0089	rRNA binding
FBF26_RS02570	COG0088	Forms part of the polypeptide exit tunnel
FBF26_RS02575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FBF26_RS02585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FBF26_RS02595	COG1666	GTP binding
FBF26_RS02600	COG0049	tRNA binding
FBF26_RS02605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FBF26_RS02610	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FBF26_RS02615	COG0085	RNA polymerase activity
FBF26_RS02625	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FBF26_RS02635	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FBF26_RS02640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FBF26_RS02645	COG0740	serine-type endopeptidase activity
FBF26_RS02655	COG0544	peptidyl-prolyl cis-trans isomerase activity
FBF26_RS02685	COG0277	FAD linked oxidase domain protein
FBF26_RS02725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FBF26_RS02735	COG1181	Belongs to the D-alanine--D-alanine ligase family
FBF26_RS02740	COG0330	HflC and HflK could
FBF26_RS02780	COG0366	Alpha amylase catalytic
FBF26_RS02805	COG0742	ribosomal rna small subunit methyltransferase
FBF26_RS02815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FBF26_RS02825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FBF26_RS02830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF26_RS02835	COG4956	integral membrane protein (PIN domain superfamily)
FBF26_RS02840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FBF26_RS02855	COG0195	Participates in both transcription termination and antitermination
FBF26_RS02880	COG0492	ferredoxin-NADP+ reductase activity
FBF26_RS02890	COG1132	(ABC) transporter
FBF26_RS02895	COG0072	phenylalanine-tRNA ligase activity
FBF26_RS02895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF26_RS02950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FBF26_RS02985	COG0336	Belongs to the RNA methyltransferase TrmD family
FBF26_RS02990	COG1837	Belongs to the UPF0109 family
FBF26_RS02995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FBF26_RS03000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FBF26_RS03010	COG0849	cell division
FBF26_RS03020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FBF26_RS03030	COG0228	four-way junction DNA binding
FBF26_RS03055	COG1104	cysteine desulfurase activity
FBF26_RS03070	COG0084	hydrolase, TatD family'
FBF26_RS03075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FBF26_RS03085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FBF26_RS03110	COG0149	triose-phosphate isomerase activity
FBF26_RS03115	COG0126	phosphoglycerate kinase activity
FBF26_RS03120	COG0469	pyruvate kinase activity
FBF26_RS03125	COG0571	ribonuclease III activity
FBF26_RS03150	COG0495	leucyl-tRNA aminoacylation
FBF26_RS03160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FBF26_RS03170	COG0280	phosphate acetyltransferase
FBF26_RS03185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FBF26_RS03200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FBF26_RS03210	COG0501	Belongs to the peptidase M48B family
FBF26_RS03215	COG1704	LemA family
FBF26_RS03225	COG1131	(ABC) transporter
FBF26_RS03255	COG0747	negative chemotaxis
FBF26_RS03265	COG1950	PFAM Membrane protein of
FBF26_RS03275	COG0322	excinuclease ABC activity
FBF26_RS03310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FBF26_RS03315	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FBF26_RS03325	COG0154	amidase activity
FBF26_RS03345	COG0556	nucleotide-excision repair
FBF26_RS03350	COG1611	Belongs to the LOG family
FBF26_RS03360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FBF26_RS03370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FBF26_RS03375	COG3959	Transketolase, thiamine diphosphate binding domain
FBF26_RS03385	COG0698	ribose 5-phosphate isomerase
FBF26_RS03405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FBF26_RS03415	COG0335	large ribosomal subunit rRNA binding
FBF26_RS03420	COG0281	malic enzyme
FBF26_RS03425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FBF26_RS03445	COG0051	transcription antitermination factor activity, RNA binding
FBF26_RS03470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FBF26_RS03475	COG0343	queuine tRNA-ribosyltransferase activity
FBF26_RS03485	COG1573	uracil-dna glycosylase
FBF26_RS03515	COG1132	(ABC) transporter
FBF26_RS03520	COG0586	Pfam SNARE associated Golgi protein
FBF26_RS03525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FBF26_RS03550	COG1136	(ABC) transporter
FBF26_RS03565	COG2925	Exonuclease
FBF26_RS03570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FBF26_RS03575	COG1388	LysM domain
FBF26_RS03575	COG3942	CHAP domain
FBF26_RS03615	COG3942	CHAP domain
FBF26_RS03650	COG1733	regulation of RNA biosynthetic process
FBF26_RS03675	COG0673	inositol 2-dehydrogenase activity
FBF26_RS03680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF26_RS03685	COG1051	belongs to the nudix hydrolase family
FBF26_RS03730	COG5002	protein histidine kinase activity
FBF26_RS03740	COG2204	response regulator
FBF26_RS03745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FBF26_RS03780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FBF26_RS03785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FBF26_RS03810	COG4968	Prepilin-type N-terminal cleavage methylation domain
FBF26_RS03815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FBF26_RS03835	COG0542	response to heat
FBF26_RS03890	COG0588	phosphoglycerate mutase activity
FBF26_RS03900	COG1418	mRNA catabolic process
FBF26_RS03905	COG1214	PFAM Peptidase M22, glycoprotease
FBF26_RS03910	COG0802	atpase or kinase
FBF26_RS03940	COG1459	type II secretion system
FBF26_RS03960	COG0572	uridine kinase
FBF26_RS03965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FBF26_RS03970	COG0668	transmembrane transport
FBF26_RS03995	COG1194	a g-specific adenine glycosylase
FBF26_RS04010	COG0300	oxidoreductase activity
FBF26_RS04020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FBF26_RS04025	COG2255	four-way junction helicase activity
FBF26_RS04040	COG0632	four-way junction helicase activity
FBF26_RS04045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FBF26_RS04050	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FBF26_RS04065	COG0217	transcriptional regulatory protein
FBF26_RS04095	COG0189	ligase activity
FBF26_RS04125	COG0484	heat shock protein binding
FBF26_RS04140	COG0443	Heat shock 70 kDa protein
FBF26_RS04145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FBF26_RS04155	COG1420	regulation of RNA biosynthetic process
FBF26_RS04165	COG0194	GDP metabolic process
FBF26_RS04185	COG0481	GTPase activity
FBF26_RS04220	COG0481	GTPase activity
FBF26_RS04230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FBF26_RS04235	COG0037	tRNA processing
FBF26_RS04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FBF26_RS04325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FBF26_RS04330	COG2137	regulation of response to DNA damage stimulus
FBF26_RS04345	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FBF26_RS04365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FBF26_RS04365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FBF26_RS04375	COG0477	Major facilitator Superfamily
FBF26_RS04380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FBF26_RS04420	COG1288	antiporter activity
FBF26_RS04425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FBF26_RS04460	COG1204	response to ionizing radiation
FBF26_RS04475	COG1132	(ABC) transporter
FBF26_RS04515	COG0765	amino acid transport
FBF26_RS04520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FBF26_RS04530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FBF26_RS04540	COG0542	response to heat
FBF26_RS04550	COG1136	(ABC) transporter
FBF26_RS04570	COG0726	polysaccharide deacetylase
FBF26_RS04575	COG1872	DUF167
FBF26_RS04580	COG3620	sequence-specific DNA binding
FBF26_RS04585	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FBF26_RS04600	COG0732	type I restriction modification DNA specificity domain
FBF26_RS04615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FBF26_RS04620	COG2003	Belongs to the UPF0758 family
FBF26_RS04645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FBF26_RS04645	COG1328	CTP reductase activity
FBF26_RS04660	COG1131	(ABC) transporter
FBF26_RS04665	COG5002	protein histidine kinase activity
FBF26_RS04665	COG3850	Histidine kinase
FBF26_RS04675	COG1619	proteins homologs of microcin C7 resistance protein MccF
FBF26_RS04705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FBF26_RS04755	COG0662	Cupin 2, conserved barrel domain protein
FBF26_RS04755	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FBF26_RS04760	COG1088	dTDP-glucose 4,6-dehydratase activity
FBF26_RS04790	COG1215	transferase activity, transferring glycosyl groups
FBF26_RS04815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FBF26_RS04835	COG1216	Glycosyl transferase, family 2
FBF26_RS04835	COG0438	transferase activity, transferring glycosyl groups
FBF26_RS04870	COG0594	ribonuclease P activity
FBF26_RS04875	COG0230	Belongs to the bacterial ribosomal protein bL34 family