locus-tag	class	description
TRUGW13939_00001	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_00009	COG1053	succinate dehydrogenase
TRUGW13939_00066	COG0017	Asparaginyl-tRNA synthetase
TRUGW13939_00084	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TRUGW13939_00132	COG0513	Belongs to the DEAD box helicase family
TRUGW13939_00137	COG0534	Mate efflux family protein
TRUGW13939_00139	COG0513	Belongs to the DEAD box helicase family
TRUGW13939_00165	COG2205	protein histidine kinase activity
TRUGW13939_00165	COG0784	Response regulator, receiver
TRUGW13939_00217	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TRUGW13939_00236	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TRUGW13939_00236	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_00236	COG3321	synthase
TRUGW13939_00236	COG0318	PFAM AMP-dependent synthetase and ligase
TRUGW13939_00236	COG0300	oxidoreductase activity
TRUGW13939_00257	COG0666	response to abiotic stimulus
TRUGW13939_00262	COG2808	Putative FMN-binding domain
TRUGW13939_00270	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_00274	COG1051	belongs to the nudix hydrolase family
TRUGW13939_00293	COG0604	alcohol dehydrogenase
TRUGW13939_00295	COG1012	belongs to the aldehyde dehydrogenase family
TRUGW13939_00342	COG0833	amino acid
TRUGW13939_00364	COG1418	mRNA catabolic process
TRUGW13939_00370	COG0363	glucosamine-6-phosphate deaminase activity
TRUGW13939_00389	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TRUGW13939_00476	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_00483	COG4178	(ABC) transporter
TRUGW13939_00508	COG0037	tRNA processing
TRUGW13939_00686	COG0688	phosphatidylethanolamine metabolic process
TRUGW13939_00687	COG2813	Specifically methylates the guanine in position
TRUGW13939_00698	COG0251	oxidation-reduction process
TRUGW13939_00710	COG0484	heat shock protein binding
TRUGW13939_00793	COG0109	protoheme IX farnesyltransferase activity
TRUGW13939_00801	COG3693	PFAM glycoside hydrolase, family 10
TRUGW13939_00862	COG1902	pentaerythritol trinitrate reductase activity
TRUGW13939_00893	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_00900	COG2814	Major facilitator Superfamily
TRUGW13939_00916	COG1472	Belongs to the glycosyl hydrolase 3 family
TRUGW13939_00945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TRUGW13939_00954	COG2267	carboxylic ester hydrolase activity
TRUGW13939_00977	COG0318	PFAM AMP-dependent synthetase and ligase
TRUGW13939_00998	COG0673	inositol 2-dehydrogenase activity
TRUGW13939_01004	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TRUGW13939_01253	COG3791	Glutathione-dependent formaldehyde-activating
TRUGW13939_01256	COG2814	Major facilitator Superfamily
TRUGW13939_01352	COG0667	Aldo Keto reductase
TRUGW13939_01370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TRUGW13939_01411	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TRUGW13939_01418	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_01465	COG1335	isochorismatase
TRUGW13939_01514	COG0133	tryptophan synthase activity
TRUGW13939_01592	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TRUGW13939_01626	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TRUGW13939_01696	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TRUGW13939_01703	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TRUGW13939_01734	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TRUGW13939_01761	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TRUGW13939_01785	COG3976	FMN-binding domain protein
TRUGW13939_01785	COG1053	succinate dehydrogenase
TRUGW13939_01797	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TRUGW13939_01809	COG2072	flavoprotein involved in K transport
TRUGW13939_01908	COG2815	serine threonine protein kinase
TRUGW13939_01908	COG0515	serine threonine protein kinase
TRUGW13939_01909	COG2814	Major facilitator Superfamily
TRUGW13939_01934	COG0736	holo-[acyl-carrier-protein] synthase activity
TRUGW13939_01979	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TRUGW13939_02068	COG2814	Major facilitator Superfamily
TRUGW13939_02068	COG0477	Major facilitator Superfamily
TRUGW13939_02092	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TRUGW13939_02118	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TRUGW13939_02192	COG0156	8-amino-7-oxononanoate synthase activity
TRUGW13939_02222	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TRUGW13939_02223	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TRUGW13939_02243	COG0596	Alpha beta hydrolase
TRUGW13939_02344	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TRUGW13939_02354	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TRUGW13939_02468	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_02469	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_02474	COG3321	synthase
TRUGW13939_02474	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_02474	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TRUGW13939_02474	COG0318	PFAM AMP-dependent synthetase and ligase
TRUGW13939_02474	COG0300	oxidoreductase activity
TRUGW13939_02518	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_02534	COG0625	glutathione transferase activity
TRUGW13939_02583	COG1063	alcohol dehydrogenase
TRUGW13939_02597	COG1899	peptidyl-lysine modification to peptidyl-hypusine
TRUGW13939_02603	COG1113	amino acid transport
TRUGW13939_02642	COG0237	dephospho-CoA kinase activity
TRUGW13939_02666	COG2814	Major facilitator Superfamily
TRUGW13939_02668	COG0277	FAD linked oxidase domain protein
TRUGW13939_02698	COG2217	Heavy metal translocating P-type atpase
TRUGW13939_02728	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TRUGW13939_02735	COG0666	response to abiotic stimulus
TRUGW13939_02766	COG0316	Belongs to the HesB IscA family
TRUGW13939_02771	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TRUGW13939_02792	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TRUGW13939_02813	COG1902	pentaerythritol trinitrate reductase activity
TRUGW13939_02951	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TRUGW13939_02954	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TRUGW13939_03008	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TRUGW13939_03012	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_03028	COG0473	3-isopropylmalate dehydrogenase activity
TRUGW13939_03050	COG0542	response to heat
TRUGW13939_03126	COG2814	Major facilitator Superfamily
TRUGW13939_03159	COG5441	Belongs to the UPF0261 family
TRUGW13939_03293	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TRUGW13939_03293	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TRUGW13939_03398	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TRUGW13939_03473	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TRUGW13939_03483	COG0285	dihydrofolate synthase activity
TRUGW13939_03565	COG1231	oxidoreductase activity
TRUGW13939_03608	COG0017	Asparaginyl-tRNA synthetase
TRUGW13939_03676	COG1404	Belongs to the peptidase S8 family
TRUGW13939_03746	COG4221	oxidoreductase activity
TRUGW13939_03773	COG0484	heat shock protein binding
TRUGW13939_03783	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TRUGW13939_03869	COG1793	dna ligase
TRUGW13939_03889	COG2351	hydroxyisourate hydrolase activity
TRUGW13939_03961	COG1881	PFAM PEBP family protein
TRUGW13939_03982	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TRUGW13939_04023	COG1078	dGTPase activity
TRUGW13939_04081	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TRUGW13939_04169	COG1448	Aminotransferase
TRUGW13939_04209	COG2814	Major facilitator Superfamily
TRUGW13939_04227	COG0625	glutathione transferase activity
TRUGW13939_04277	COG0488	(ABC) transporter
TRUGW13939_04391	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_04394	COG5265	(ABC) transporter
TRUGW13939_04399	COG0515	serine threonine protein kinase
TRUGW13939_04435	COG1064	alcohol dehydrogenase
TRUGW13939_04464	COG0101	tRNA pseudouridine synthase activity
TRUGW13939_04536	COG1446	asparaginase
TRUGW13939_04545	COG1073	alpha beta
TRUGW13939_04553	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TRUGW13939_04570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TRUGW13939_04620	COG3961	Belongs to the TPP enzyme family
TRUGW13939_04631	COG4221	oxidoreductase activity
TRUGW13939_04667	COG1335	isochorismatase
TRUGW13939_04674	COG0071	Belongs to the small heat shock protein (HSP20) family
TRUGW13939_04693	COG2755	lipolytic protein G-D-S-L family
TRUGW13939_04693	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
TRUGW13939_04735	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
TRUGW13939_04776	COG2271	Major facilitator Superfamily
TRUGW13939_04795	COG2124	cytochrome p450
TRUGW13939_04814	COG0688	phosphatidylethanolamine metabolic process
TRUGW13939_04855	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_04858	COG0446	pyridine nucleotide-disulphide oxidoreductase
TRUGW13939_04866	COG4689	acetoacetate decarboxylase
TRUGW13939_04867	COG1132	(ABC) transporter
TRUGW13939_04912	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TRUGW13939_04927	COG3345	alpha-galactosidase
TRUGW13939_04943	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TRUGW13939_04979	COG0657	acetylesterase activity
TRUGW13939_04994	COG0515	serine threonine protein kinase
TRUGW13939_04994	COG0457	Tetratricopeptide repeat
TRUGW13939_05032	COG1228	amidohydrolase
TRUGW13939_05065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRUGW13939_05065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRUGW13939_05124	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRUGW13939_05124	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRUGW13939_05159	COG1404	Belongs to the peptidase S8 family
TRUGW13939_05316	COG1902	pentaerythritol trinitrate reductase activity
TRUGW13939_05323	COG4122	O-methyltransferase activity
TRUGW13939_05349	COG0076	glutamate decarboxylase activity
TRUGW13939_05358	COG0823	Involved in the tonB-independent uptake of proteins
TRUGW13939_05552	COG0513	Belongs to the DEAD box helicase family
TRUGW13939_05594	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TRUGW13939_05611	COG0363	glucosamine-6-phosphate deaminase activity
TRUGW13939_05620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TRUGW13939_05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TRUGW13939_05704	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TRUGW13939_05704	COG0512	Glutamine amidotransferase of anthranilate synthase
TRUGW13939_05807	COG2843	Capsule synthesis protein
TRUGW13939_05840	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TRUGW13939_05887	COG1012	belongs to the aldehyde dehydrogenase family
TRUGW13939_05891	COG0179	Fumarylacetoacetate (FAA) hydrolase
TRUGW13939_05901	COG2272	Belongs to the type-B carboxylesterase lipase family
TRUGW13939_05924	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TRUGW13939_05950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TRUGW13939_05954	COG0076	glutamate decarboxylase activity
TRUGW13939_06000	COG1473	amidohydrolase
TRUGW13939_06025	COG0009	L-threonylcarbamoyladenylate synthase
TRUGW13939_06027	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TRUGW13939_06283	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_06304	COG0017	Asparaginyl-tRNA synthetase
TRUGW13939_06367	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TRUGW13939_06383	COG0484	heat shock protein binding
TRUGW13939_06511	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TRUGW13939_06511	COG0517	IMP dehydrogenase activity
TRUGW13939_06541	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TRUGW13939_06545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TRUGW13939_06577	COG1252	NADH dehydrogenase
TRUGW13939_06609	COG3903	Transcriptional regulator
TRUGW13939_06609	COG3629	intracellular signal transduction
TRUGW13939_06623	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TRUGW13939_06642	COG0402	S-adenosylhomocysteine deaminase activity
TRUGW13939_06644	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TRUGW13939_06644	COG2124	cytochrome p450
TRUGW13939_06645	COG2124	cytochrome p450
TRUGW13939_06673	COG1063	alcohol dehydrogenase
TRUGW13939_06675	COG1643	Atp-dependent helicase
TRUGW13939_06679	COG0492	ferredoxin-NADP+ reductase activity
TRUGW13939_06685	COG0393	Putative heavy-metal-binding
TRUGW13939_06686	COG0667	Aldo Keto reductase
TRUGW13939_06713	COG1228	amidohydrolase
TRUGW13939_06795	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_06810	COG2814	Major facilitator Superfamily
TRUGW13939_06824	COG0833	amino acid
TRUGW13939_06853	COG0174	glutamine synthetase
TRUGW13939_06863	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TRUGW13939_06866	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_06886	COG1073	alpha beta
TRUGW13939_06922	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TRUGW13939_06980	COG0477	Major facilitator Superfamily
TRUGW13939_07030	COG0714	Associated with various cellular activities
TRUGW13939_07080	COG2226	methyltransferase
TRUGW13939_07093	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TRUGW13939_07203	COG0445	tRNA wobble uridine modification
TRUGW13939_07332	COG0667	Aldo Keto reductase
TRUGW13939_07516	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_07520	COG3345	alpha-galactosidase
TRUGW13939_07589	COG0477	Major facilitator Superfamily
TRUGW13939_07697	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TRUGW13939_07774	COG0698	ribose 5-phosphate isomerase
TRUGW13939_07775	COG0149	triose-phosphate isomerase activity
TRUGW13939_07776	COG0167	dihydroorotate dehydrogenase activity
TRUGW13939_07787	COG0246	Mannitol dehydrogenase
TRUGW13939_07801	COG1111	helicase
TRUGW13939_07801	COG1205	dead DEAH box helicase
TRUGW13939_07813	COG2814	Major facilitator Superfamily
TRUGW13939_07827	COG1012	belongs to the aldehyde dehydrogenase family
TRUGW13939_07854	COG0667	Aldo Keto reductase
TRUGW13939_07863	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TRUGW13939_07939	COG3119	arylsulfatase activity
TRUGW13939_07991	COG0193	aminoacyl-tRNA hydrolase activity
TRUGW13939_08009	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TRUGW13939_08062	COG1160	GTP binding
TRUGW13939_08063	COG0438	transferase activity, transferring glycosyl groups
TRUGW13939_08071	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TRUGW13939_08083	COG2169	Transcriptional regulator
TRUGW13939_08083	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TRUGW13939_08086	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TRUGW13939_08087	COG4948	Mandelate Racemase Muconate Lactonizing
TRUGW13939_08088	COG2815	serine threonine protein kinase
TRUGW13939_08088	COG0515	serine threonine protein kinase
TRUGW13939_08129	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TRUGW13939_08140	COG5383	Protein conserved in bacteria
TRUGW13939_08152	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TRUGW13939_08199	COG0430	RNA-3'-phosphate cyclase activity
TRUGW13939_08272	COG0163	prenyltransferase activity
TRUGW13939_08287	COG1362	aminopeptidase activity
TRUGW13939_08294	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TRUGW13939_08307	COG0402	S-adenosylhomocysteine deaminase activity
TRUGW13939_08349	COG0596	Alpha beta hydrolase
TRUGW13939_08462	COG3119	arylsulfatase activity
TRUGW13939_08527	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TRUGW13939_08544	COG0028	Belongs to the TPP enzyme family
TRUGW13939_08544	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TRUGW13939_08564	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_08665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TRUGW13939_08722	COG0513	Belongs to the DEAD box helicase family
TRUGW13939_08741	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TRUGW13939_08766	COG0174	glutamine synthetase
TRUGW13939_08768	COG1132	(ABC) transporter
TRUGW13939_08794	COG5265	(ABC) transporter
TRUGW13939_08802	COG1012	belongs to the aldehyde dehydrogenase family
TRUGW13939_08857	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TRUGW13939_08875	COG0028	Belongs to the TPP enzyme family
TRUGW13939_08901	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TRUGW13939_08944	COG0477	Major facilitator Superfamily
TRUGW13939_08988	COG2814	Major facilitator Superfamily
TRUGW13939_08999	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TRUGW13939_09041	COG0277	FAD linked oxidase domain protein
TRUGW13939_09055	COG0667	Aldo Keto reductase
TRUGW13939_09072	COG0443	Heat shock 70 kDa protein
TRUGW13939_09082	COG0542	response to heat
TRUGW13939_09098	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_09136	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_09143	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TRUGW13939_09152	COG0604	alcohol dehydrogenase
TRUGW13939_09161	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TRUGW13939_09187	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TRUGW13939_09194	COG0424	maF-like protein
TRUGW13939_09248	COG1024	Enoyl-CoA hydratase
TRUGW13939_09251	COG0673	inositol 2-dehydrogenase activity
TRUGW13939_09273	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TRUGW13939_09283	COG4336	lyase activity
TRUGW13939_09347	COG2814	Major facilitator Superfamily
TRUGW13939_09369	COG1902	pentaerythritol trinitrate reductase activity
TRUGW13939_09418	COG0667	Aldo Keto reductase
TRUGW13939_09513	COG0571	ribonuclease III activity
TRUGW13939_09539	COG3239	Fatty acid desaturase
TRUGW13939_09550	COG0833	amino acid
TRUGW13939_09557	COG1473	amidohydrolase
TRUGW13939_09708	COG3903	Transcriptional regulator
TRUGW13939_09708	COG3629	intracellular signal transduction
TRUGW13939_09820	COG5002	protein histidine kinase activity
TRUGW13939_09874	COG1132	(ABC) transporter
TRUGW13939_09889	COG2070	2-Nitropropane dioxygenase
TRUGW13939_09898	COG0523	cobalamin synthesis protein
TRUGW13939_09934	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TRUGW13939_09995	COG0123	including yeast histone deacetylase and acetoin utilization protein
TRUGW13939_10018	COG0604	alcohol dehydrogenase
TRUGW13939_10085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TRUGW13939_10123	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TRUGW13939_10151	COG0300	oxidoreductase activity
TRUGW13939_10177	COG2217	Heavy metal translocating P-type atpase
TRUGW13939_10186	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TRUGW13939_10197	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TRUGW13939_10199	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TRUGW13939_10200	COG4266	Belongs to the allantoicase family
TRUGW13939_10217	COG2130	NADP-dependent
TRUGW13939_10247	COG0366	Alpha amylase catalytic
TRUGW13939_10278	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TRUGW13939_10308	COG0477	Major facilitator Superfamily
TRUGW13939_10354	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_10355	COG0514	ATP-dependent DNA helicase (RecQ)
TRUGW13939_10407	COG2814	Major facilitator Superfamily
TRUGW13939_10431	COG2267	carboxylic ester hydrolase activity
TRUGW13939_10432	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TRUGW13939_10443	COG0833	amino acid
TRUGW13939_10461	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TRUGW13939_10462	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TRUGW13939_10539	COG3118	belongs to the thioredoxin family
TRUGW13939_10578	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TRUGW13939_10590	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_10590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TRUGW13939_10590	COG0318	PFAM AMP-dependent synthetase and ligase
TRUGW13939_10590	COG0300	oxidoreductase activity
TRUGW13939_10590	COG3321	synthase
TRUGW13939_10615	COG2267	carboxylic ester hydrolase activity
TRUGW13939_10646	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TRUGW13939_10719	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TRUGW13939_10720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TRUGW13939_10775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TRUGW13939_10815	COG0047	phosphoribosylformylglycinamidine synthase activity
TRUGW13939_10815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TRUGW13939_10849	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TRUGW13939_10864	COG1132	(ABC) transporter
TRUGW13939_10886	COG2132	Multicopper oxidase
TRUGW13939_10889	COG1472	Belongs to the glycosyl hydrolase 3 family
TRUGW13939_10930	COG3903	Transcriptional regulator
TRUGW13939_10930	COG3629	intracellular signal transduction
TRUGW13939_10961	COG2271	Major facilitator Superfamily
TRUGW13939_10963	COG3119	arylsulfatase activity
TRUGW13939_11038	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TRUGW13939_11038	COG2169	Transcriptional regulator
TRUGW13939_11049	COG0604	alcohol dehydrogenase
TRUGW13939_11115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TRUGW13939_11121	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TRUGW13939_11153	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TRUGW13939_11173	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TRUGW13939_11205	COG1024	Enoyl-CoA hydratase
TRUGW13939_11275	COG2814	Major facilitator Superfamily
TRUGW13939_11279	COG1073	alpha beta
TRUGW13939_11363	COG0156	8-amino-7-oxononanoate synthase activity
TRUGW13939_11414	COG2226	methyltransferase
TRUGW13939_11503	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TRUGW13939_11614	COG1335	isochorismatase
TRUGW13939_11621	COG0724	RNA recognition motif
TRUGW13939_11659	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_11664	COG1028	Short-chain dehydrogenase reductase Sdr
TRUGW13939_11691	COG0463	Glycosyl transferase, family 2
TRUGW13939_11715	COG1064	alcohol dehydrogenase
TRUGW13939_11857	COG1072	(Pantothenic acid kinase))
TRUGW13939_11860	COG0688	phosphatidylethanolamine metabolic process
TRUGW13939_11907	COG2814	Major facilitator Superfamily
TRUGW13939_11929	COG2271	Major facilitator Superfamily
TRUGW13939_12012	COG0514	ATP-dependent DNA helicase (RecQ)