locus-tag	class	description
TF3313_RS00015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TF3313_RS00025	COG0335	large ribosomal subunit rRNA binding
TF3313_RS00045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TF3313_RS00060	COG3590	peptidase
TF3313_RS00075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TF3313_RS00080	COG1120	ATPase activity
TF3313_RS00095	COG0543	2 iron, 2 sulfur cluster binding
TF3313_RS00100	COG0167	dihydroorotate dehydrogenase activity
TF3313_RS00115	COG1285	pathogenesis
TF3313_RS00125	COG0101	tRNA pseudouridine synthase activity
TF3313_RS00135	COG1797	cobyrinic acid a,c-diamide synthase activity
TF3313_RS00140	COG5297	Belongs to the glycosyl hydrolase family 6
TF3313_RS00140	COG3250	beta-galactosidase activity
TF3313_RS00150	COG1629	transport
TF3313_RS00150	COG4206	TonB-dependent receptor
TF3313_RS00165	COG1629	transport
TF3313_RS00180	COG1215	transferase activity, transferring glycosyl groups
TF3313_RS00190	COG2385	sporulation resulting in formation of a cellular spore
TF3313_RS00190	COG2247	cell wall binding repeat
TF3313_RS00195	COG2211	Major facilitator Superfamily
TF3313_RS00200	COG3876	Protein conserved in bacteria
TF3313_RS00215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TF3313_RS00220	COG0561	phosphatase activity
TF3313_RS00290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TF3313_RS00320	COG2274	protein secretion by the type I secretion system
TF3313_RS00340	COG0438	transferase activity, transferring glycosyl groups
TF3313_RS00400	COG2274	protein secretion by the type I secretion system
TF3313_RS00440	COG1187	pseudouridine synthase activity
TF3313_RS00465	COG1132	(ABC) transporter
TF3313_RS00470	COG1132	(ABC) transporter
TF3313_RS00480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
TF3313_RS00495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TF3313_RS00515	COG2223	nitrite transmembrane transporter activity
TF3313_RS00520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TF3313_RS00530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TF3313_RS00535	COG0543	2 iron, 2 sulfur cluster binding
TF3313_RS00540	COG0493	'glutamate synthase
TF3313_RS00545	COG3015	lipoprotein NlpE involved in copper resistance
TF3313_RS00550	COG1051	belongs to the nudix hydrolase family
TF3313_RS00555	COG1970	mechanosensitive ion channel activity
TF3313_RS00560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TF3313_RS00570	COG2972	Histidine kinase
TF3313_RS00570	COG0745	RESPONSE REGULATOR receiver
TF3313_RS00585	COG1136	(ABC) transporter
TF3313_RS00585	COG4591	ABC-type transport system involved in lipoprotein release permease component
TF3313_RS00655	COG0438	transferase activity, transferring glycosyl groups
TF3313_RS00665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TF3313_RS00680	COG0237	dephospho-CoA kinase activity
TF3313_RS00690	COG1862	Preprotein translocase
TF3313_RS00695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TF3313_RS00700	COG0252	asparaginase activity
TF3313_RS00720	COG1629	transport
TF3313_RS00740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TF3313_RS00750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TF3313_RS00760	COG1011	Hydrolase
TF3313_RS00765	COG1595	DNA-templated transcription, initiation
TF3313_RS00835	COG3189	MarR family transcriptional regulator
TF3313_RS00845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TF3313_RS00855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TF3313_RS00860	COG0235	Class ii aldolase
TF3313_RS00870	COG4806	L-rhamnose isomerase
TF3313_RS00875	COG1070	Carbohydrate kinase
TF3313_RS00890	COG0442	prolyl-tRNA aminoacylation
TF3313_RS00895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TF3313_RS00905	COG1704	LemA family
TF3313_RS00910	COG0501	Belongs to the peptidase M48B family
TF3313_RS00915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TF3313_RS00920	COG0126	phosphoglycerate kinase activity
TF3313_RS00925	COG0534	Mate efflux family protein
TF3313_RS00965	COG0484	heat shock protein binding
TF3313_RS00970	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TF3313_RS00975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS00980	COG1193	negative regulation of DNA recombination
TF3313_RS00990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TF3313_RS01000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TF3313_RS01020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TF3313_RS01030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TF3313_RS01045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
TF3313_RS01050	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TF3313_RS01065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TF3313_RS01085	COG2264	protein methyltransferase activity
TF3313_RS01105	COG1373	ATPase (AAA superfamily
TF3313_RS01110	COG4804	nuclease activity
TF3313_RS01135	COG3152	Membrane
TF3313_RS01170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TF3313_RS01175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TF3313_RS01180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TF3313_RS01205	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
TF3313_RS01210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TF3313_RS01230	COG4771	TonB-dependent receptor
TF3313_RS01235	COG0702	epimerase
TF3313_RS01240	COG3250	beta-galactosidase activity
TF3313_RS01250	COG2431	L-lysine efflux transmembrane transporter activity
TF3313_RS01255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TF3313_RS01260	COG3339	Conserved Protein
TF3313_RS01270	COG0738	Major facilitator superfamily
TF3313_RS01275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TF3313_RS01275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TF3313_RS01280	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TF3313_RS01285	COG2885	chlorophyll binding
TF3313_RS01290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TF3313_RS01290	COG1333	cytochrome c biogenesis protein
TF3313_RS01295	COG1506	peptidase
TF3313_RS01295	COG0823	Involved in the tonB-independent uptake of proteins
TF3313_RS01305	COG3537	Alpha-1,2-mannosidase
TF3313_RS01315	COG0534	Mate efflux family protein
TF3313_RS01320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TF3313_RS01325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TF3313_RS01330	COG0297	glycogen (starch) synthase activity
TF3313_RS01460	COG0681	Belongs to the peptidase S26 family
TF3313_RS01495	COG0681	Belongs to the peptidase S26 family
TF3313_RS01505	COG1216	Glycosyl transferase, family 2
TF3313_RS01505	COG0463	Glycosyl transferase, family 2
TF3313_RS01510	COG3591	Belongs to the peptidase S1B family
TF3313_RS01525	COG2255	four-way junction helicase activity
TF3313_RS01590	COG2860	membrane
TF3313_RS01595	COG4771	TonB-dependent receptor
TF3313_RS01605	COG1610	YqeY-like protein
TF3313_RS01610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TF3313_RS01625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TF3313_RS01630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TF3313_RS01635	COG0772	Belongs to the SEDS family
TF3313_RS01640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TF3313_RS01645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TF3313_RS01650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TF3313_RS01655	COG0768	penicillin binding
TF3313_RS01665	COG0275	rRNA processing
TF3313_RS01680	COG0698	ribose 5-phosphate isomerase
TF3313_RS01685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TF3313_RS01690	COG0427	acetyl-CoA hydrolase
TF3313_RS01695	COG0546	phosphoglycolate phosphatase activity
TF3313_RS01735	COG1595	DNA-templated transcription, initiation
TF3313_RS01745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TF3313_RS01750	COG2333	competence protein COMEC
TF3313_RS01750	COG0658	competence protein
TF3313_RS01755	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TF3313_RS01760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS01785	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TF3313_RS01785	COG0519	Catalyzes the synthesis of GMP from XMP
TF3313_RS01800	COG0501	Belongs to the peptidase M48B family
TF3313_RS01805	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TF3313_RS01810	COG0534	Mate efflux family protein
TF3313_RS01815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TF3313_RS01835	COG0312	modulator of DNA gyrase
TF3313_RS01845	COG3250	beta-galactosidase activity
TF3313_RS01850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TF3313_RS01870	COG0363	glucosamine-6-phosphate deaminase activity
TF3313_RS01895	COG0577	efflux transmembrane transporter activity
TF3313_RS01895	COG1136	(ABC) transporter
TF3313_RS01900	COG1136	(ABC) transporter
TF3313_RS01910	COG4974	Belongs to the 'phage' integrase family
TF3313_RS01930	COG3645	SOS response
TF3313_RS01935	COG0693	protein deglycase activity
TF3313_RS01950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TF3313_RS01950	COG2207	Transcriptional regulator
TF3313_RS01975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TF3313_RS02020	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TF3313_RS02040	COG4953	penicillin-binding protein 1C
TF3313_RS02045	COG2373	Large extracellular alpha-helical protein
TF3313_RS02050	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TF3313_RS02060	COG0165	Argininosuccinate lyase
TF3313_RS02075	COG0328	RNA-DNA hybrid ribonuclease activity
TF3313_RS02075	COG3341	Caulimovirus viroplasmin
TF3313_RS02085	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
TF3313_RS02095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TF3313_RS02105	COG1160	GTP binding
TF3313_RS02110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TF3313_RS02115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TF3313_RS02125	COG3537	Alpha-1,2-mannosidase
TF3313_RS02140	COG3940	Belongs to the glycosyl hydrolase 43 family
TF3313_RS02150	COG4771	TonB-dependent receptor
TF3313_RS02160	COG1506	peptidase
TF3313_RS02160	COG4946	Tricorn protease homolog
TF3313_RS02160	COG0823	Involved in the tonB-independent uptake of proteins
TF3313_RS02170	COG1629	transport
TF3313_RS02170	COG4206	TonB-dependent receptor
TF3313_RS02200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TF3313_RS02205	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TF3313_RS02220	COG0180	Tryptophanyl-tRNA synthetase
TF3313_RS02235	COG0039	L-malate dehydrogenase activity
TF3313_RS02240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TF3313_RS02245	COG0569	domain protein
TF3313_RS02250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TF3313_RS02260	COG4206	TonB-dependent receptor
TF3313_RS02300	COG1396	sequence-specific DNA binding
TF3313_RS02310	COG3550	peptidyl-serine autophosphorylation
TF3313_RS02315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TF3313_RS02325	COG0556	nucleotide-excision repair
TF3313_RS02340	COG3142	Participates in the control of copper homeostasis
TF3313_RS02365	COG0535	radical SAM domain protein
TF3313_RS02380	COG3475	LICD family
TF3313_RS02390	COG0584	glycerophosphoryl diester phosphodiesterase
TF3313_RS02405	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TF3313_RS02425	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TF3313_RS02440	COG4585	Histidine kinase
TF3313_RS02445	COG2197	response regulator
TF3313_RS02455	COG2852	Protein conserved in bacteria
TF3313_RS02500	COG0084	hydrolase, TatD family'
TF3313_RS02505	COG0594	ribonuclease P activity
TF3313_RS02520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TF3313_RS02535	COG1629	transport
TF3313_RS02540	COG0702	epimerase
TF3313_RS02550	COG0659	secondary active sulfate transmembrane transporter activity
TF3313_RS02555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TF3313_RS02895	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TF3313_RS02905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TF3313_RS02920	COG0793	Belongs to the peptidase S41A family
TF3313_RS02930	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TF3313_RS02935	COG0194	GDP metabolic process
TF3313_RS02940	COG1561	YicC-like family, N-terminal region
TF3313_RS02970	COG1022	Amp-dependent synthetase and ligase
TF3313_RS02975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TF3313_RS02985	COG1215	transferase activity, transferring glycosyl groups
TF3313_RS03005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TF3313_RS03010	COG0792	nuclease activity
TF3313_RS03025	COG3940	Belongs to the glycosyl hydrolase 43 family
TF3313_RS03030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TF3313_RS03035	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TF3313_RS03040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TF3313_RS03045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TF3313_RS03050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TF3313_RS03055	COG0356	it plays a direct role in the translocation of protons across the membrane
TF3313_RS03065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TF3313_RS03070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TF3313_RS03085	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
TF3313_RS03090	COG1091	dTDP-4-dehydrorhamnose reductase activity
TF3313_RS03105	COG0612	Peptidase, M16
TF3313_RS03110	COG1696	Membrane protein involved in D-alanine export
TF3313_RS03130	COG0443	Heat shock 70 kDa protein
TF3313_RS03260	COG5549	protein import
TF3313_RS03260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS03265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TF3313_RS03270	COG3386	PFAM SMP-30 Gluconolaconase
TF3313_RS03300	COG0778	Nitroreductase
TF3313_RS03300	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
TF3313_RS03310	COG2884	Cell division ATP-binding protein ftsE
TF3313_RS03315	COG0527	aspartate kinase activity
TF3313_RS03320	COG0019	diaminopimelate decarboxylase activity
TF3313_RS03335	COG0673	inositol 2-dehydrogenase activity
TF3313_RS03340	COG4771	TonB-dependent receptor
TF3313_RS03345	COG0702	epimerase
TF3313_RS03350	COG3119	arylsulfatase activity
TF3313_RS03375	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TF3313_RS03385	COG2986	histidine ammonia-lyase
TF3313_RS03410	COG4206	TonB-dependent receptor
TF3313_RS03440	COG0793	Belongs to the peptidase S41A family
TF3313_RS03445	COG1192	Involved in chromosome partitioning
TF3313_RS03450	COG1475	DNA binding
TF3313_RS03460	COG1388	LysM domain
TF3313_RS03460	COG3942	CHAP domain
TF3313_RS03465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TF3313_RS03485	COG0739	heme binding
TF3313_RS03490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TF3313_RS03495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TF3313_RS03505	COG3119	arylsulfatase activity
TF3313_RS03515	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TF3313_RS03530	COG4676	Protein conserved in bacteria
TF3313_RS03540	COG1228	amidohydrolase
TF3313_RS03550	COG3404	Formiminotransferase-cyclodeaminase
TF3313_RS03555	COG2986	histidine ammonia-lyase
TF3313_RS03575	COG2996	Protein conserved in bacteria
TF3313_RS03600	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
TF3313_RS03605	COG1136	(ABC) transporter
TF3313_RS03610	COG0733	neurotransmitter:sodium symporter activity
TF3313_RS03620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TF3313_RS03660	COG0758	DNA mediated transformation
TF3313_RS03665	COG2194	sulfuric ester hydrolase activity
TF3313_RS03670	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TF3313_RS03675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TF3313_RS03675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TF3313_RS03730	COG1482	cell wall glycoprotein biosynthetic process
TF3313_RS03735	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TF3313_RS03745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TF3313_RS03750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TF3313_RS03760	COG0066	3-isopropylmalate dehydratase activity
TF3313_RS03790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TF3313_RS03810	COG0475	glutathione-regulated potassium exporter activity
TF3313_RS03820	COG0826	peptidase U32
TF3313_RS03825	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TF3313_RS03830	COG1058	Belongs to the CinA family
TF3313_RS03830	COG1546	Belongs to the CinA family
TF3313_RS03835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TF3313_RS03855	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TF3313_RS03860	COG0540	Belongs to the ATCase OTCase family
TF3313_RS03960	COG0745	RESPONSE REGULATOR receiver
TF3313_RS03985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TF3313_RS03990	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TF3313_RS04010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TF3313_RS04015	COG1373	ATPase (AAA superfamily
TF3313_RS04045	COG1595	DNA-templated transcription, initiation
TF3313_RS04060	COG2204	response regulator
TF3313_RS04065	COG0802	atpase or kinase
TF3313_RS04075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TF3313_RS04075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TF3313_RS04120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TF3313_RS04130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TF3313_RS04135	COG2715	membrane protein required for spore maturation
TF3313_RS04140	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TF3313_RS04150	COG0495	leucyl-tRNA aminoacylation
TF3313_RS04155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TF3313_RS04160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TF3313_RS04175	COG1022	Amp-dependent synthetase and ligase
TF3313_RS04180	COG1280	lysine exporter protein (LysE YggA)
TF3313_RS04185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TF3313_RS04190	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TF3313_RS04210	COG0084	hydrolase, TatD family'
TF3313_RS04220	COG0811	peptide transport
TF3313_RS04245	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TF3313_RS04250	COG0511	ligase activity, forming carbon-carbon bonds
TF3313_RS04260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TF3313_RS04265	COG0346	lactoylglutathione lyase activity
TF3313_RS04270	COG0528	UMP kinase activity
TF3313_RS04285	COG4771	TonB-dependent receptor
TF3313_RS04290	COG0561	phosphatase activity
TF3313_RS04300	COG1482	cell wall glycoprotein biosynthetic process
TF3313_RS04305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TF3313_RS04325	COG1629	transport
TF3313_RS04330	COG0702	epimerase
TF3313_RS04355	COG0420	3'-5' exonuclease activity
TF3313_RS04365	COG1940	carbohydrate kinase activity
TF3313_RS04370	COG1703	isobutyryl-CoA mutase activity
TF3313_RS04385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TF3313_RS04390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
TF3313_RS04395	COG2233	PERMEase
TF3313_RS04400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TF3313_RS04405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TF3313_RS04405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TF3313_RS04410	COG0142	geranyltranstransferase activity
TF3313_RS04430	COG1506	peptidase
TF3313_RS04430	COG0823	Involved in the tonB-independent uptake of proteins
TF3313_RS04435	COG0116	Belongs to the methyltransferase superfamily
TF3313_RS04455	COG4948	Mandelate Racemase Muconate Lactonizing
TF3313_RS04470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TF3313_RS04470	COG0731	radical SAM domain protein
TF3313_RS04495	COG4206	TonB-dependent receptor
TF3313_RS04495	COG1629	transport
TF3313_RS04500	COG1233	COG1233 Phytoene dehydrogenase and related
TF3313_RS04505	COG2814	Major facilitator Superfamily
TF3313_RS04530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TF3313_RS04540	COG0517	IMP dehydrogenase activity
TF3313_RS04540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TF3313_RS04545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TF3313_RS04555	COG2195	Cleaves the N-terminal amino acid of tripeptides
TF3313_RS04560	COG1185	polyribonucleotide nucleotidyltransferase activity
TF3313_RS04575	COG0438	transferase activity, transferring glycosyl groups
TF3313_RS04585	COG0438	transferase activity, transferring glycosyl groups
TF3313_RS04595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TF3313_RS04600	COG3177	Filamentation induced by cAMP protein fic
TF3313_RS04610	COG0367	asparagine synthase
TF3313_RS04640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TF3313_RS04650	COG1083	cytidylyl-transferase
TF3313_RS04660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TF3313_RS04665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TF3313_RS04670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TF3313_RS04675	COG2089	acid synthase
TF3313_RS04685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TF3313_RS04685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TF3313_RS04695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TF3313_RS04700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TF3313_RS04705	COG2244	polysaccharide biosynthetic process
TF3313_RS04715	COG0673	inositol 2-dehydrogenase activity
TF3313_RS04725	COG0793	Belongs to the peptidase S41A family
TF3313_RS04725	COG3409	Peptidoglycan-binding domain 1 protein
TF3313_RS04730	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TF3313_RS04770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TF3313_RS04775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TF3313_RS04780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TF3313_RS04785	COG0571	ribonuclease III activity
TF3313_RS04795	COG0205	6-phosphofructokinase activity
TF3313_RS04800	COG0737	Belongs to the 5'-nucleotidase family
TF3313_RS04810	COG0445	tRNA wobble uridine modification
TF3313_RS04815	COG0322	excinuclease ABC activity
TF3313_RS04820	COG1490	D-aminoacyl-tRNA deacylase activity
TF3313_RS04825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS04825	COG5549	protein import
TF3313_RS04850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS04850	COG5549	protein import
TF3313_RS04865	COG5549	protein import
TF3313_RS04865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS04875	COG1234	tRNA 3'-trailer cleavage
TF3313_RS04885	COG0509	glycine decarboxylation via glycine cleavage system
TF3313_RS04890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TF3313_RS04895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TF3313_RS04925	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TF3313_RS04935	COG2204	response regulator
TF3313_RS04955	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TF3313_RS04960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TF3313_RS04970	COG2076	Multidrug Resistance protein
TF3313_RS04980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TF3313_RS04990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TF3313_RS05010	COG1944	ATP diphosphatase activity
TF3313_RS05020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TF3313_RS05025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TF3313_RS05030	COG3119	arylsulfatase activity
TF3313_RS05040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TF3313_RS05055	COG1904	glucuronate isomerase
TF3313_RS05060	COG0205	6-phosphofructokinase activity
TF3313_RS05090	COG0714	Associated with various cellular activities
TF3313_RS05100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS05100	COG5549	protein import
TF3313_RS05110	COG5549	protein import
TF3313_RS05110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS05125	COG5549	protein import
TF3313_RS05125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS05145	COG2095	MarC family integral membrane protein
TF3313_RS05150	COG0151	Belongs to the GarS family
TF3313_RS05175	COG2706	6-phosphogluconolactonase activity
TF3313_RS05195	COG1755	Isoprenylcysteine carboxyl methyltransferase
TF3313_RS05200	COG4771	TonB-dependent receptor
TF3313_RS05205	COG0702	epimerase
TF3313_RS05235	COG4771	TonB-dependent receptor
TF3313_RS05255	COG1629	transport
TF3313_RS05255	COG4206	TonB-dependent receptor
TF3313_RS05270	COG2197	response regulator
TF3313_RS05285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TF3313_RS05300	COG0423	glycine-tRNA ligase activity
TF3313_RS05315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TF3313_RS05315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TF3313_RS05390	COG4206	TonB-dependent receptor
TF3313_RS05390	COG1629	transport
TF3313_RS05410	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TF3313_RS05415	COG0745	RESPONSE REGULATOR receiver
TF3313_RS05415	COG2205	protein histidine kinase activity
TF3313_RS05415	COG3292	Two component regulator propeller
TF3313_RS05420	COG5434	Belongs to the glycosyl hydrolase 28 family
TF3313_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
TF3313_RS05435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TF3313_RS05470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TF3313_RS05490	COG2096	Adenosyltransferase
TF3313_RS05505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TF3313_RS05540	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TF3313_RS05575	COG0233	cytoplasmic translational termination
TF3313_RS05580	COG1162	GTPase activity
TF3313_RS05585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TF3313_RS05590	COG4771	TonB-dependent receptor
TF3313_RS05600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TF3313_RS05605	COG0280	phosphate acetyltransferase
TF3313_RS05610	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TF3313_RS05615	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TF3313_RS05620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TF3313_RS05635	COG0826	peptidase U32
TF3313_RS05730	COG0582	viral genome integration into host DNA
TF3313_RS05735	COG4974	Belongs to the 'phage' integrase family
TF3313_RS05770	COG1012	belongs to the aldehyde dehydrogenase family
TF3313_RS05775	COG0813	purine-nucleoside phosphorylase activity
TF3313_RS05785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TF3313_RS05795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TF3313_RS05800	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
TF3313_RS05800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TF3313_RS05805	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TF3313_RS05815	COG0284	orotidine-5'-phosphate decarboxylase activity
TF3313_RS05820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TF3313_RS05825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TF3313_RS05855	COG3956	TIGRFAM MazG family protein
TF3313_RS05860	COG3250	beta-galactosidase activity
TF3313_RS05890	COG4974	Belongs to the 'phage' integrase family
TF3313_RS05900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TF3313_RS05905	COG0598	Magnesium transport protein CorA
TF3313_RS05910	COG0606	chelatase, subunit chli
TF3313_RS05935	COG1629	transport
TF3313_RS05935	COG4206	TonB-dependent receptor
TF3313_RS05950	COG0463	Glycosyl transferase, family 2
TF3313_RS05975	COG4771	TonB-dependent receptor
TF3313_RS05995	COG4771	TonB-dependent receptor
TF3313_RS06000	COG0012	GTP binding
TF3313_RS06060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TF3313_RS06070	COG2003	Belongs to the UPF0758 family
TF3313_RS06075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TF3313_RS06095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TF3313_RS06115	COG2890	protein-(glutamine-N5) methyltransferase activity
TF3313_RS06120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TF3313_RS06120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TF3313_RS06135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TF3313_RS06155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TF3313_RS06170	COG1121	(ABC) transporter
TF3313_RS06175	COG4591	ABC-type transport system involved in lipoprotein release permease component
TF3313_RS06180	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TF3313_RS06190	COG0702	epimerase
TF3313_RS06195	COG1629	transport
TF3313_RS06220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TF3313_RS06240	COG1956	GAF domain-containing protein
TF3313_RS06245	COG0517	IMP dehydrogenase activity
TF3313_RS06245	COG0617	tRNA 3'-terminal CCA addition
TF3313_RS06245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TF3313_RS06255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TF3313_RS06285	COG0427	acetyl-CoA hydrolase
TF3313_RS06290	COG1454	alcohol dehydrogenase
TF3313_RS06295	COG1012	belongs to the aldehyde dehydrogenase family
TF3313_RS06300	COG1960	acyl-CoA dehydrogenase activity
TF3313_RS06305	COG2086	electron transfer activity
TF3313_RS06310	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TF3313_RS06320	COG1137	ATPase activity
TF3313_RS06330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TF3313_RS06355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TF3313_RS06360	COG0514	ATP-dependent DNA helicase (RecQ)
TF3313_RS06365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TF3313_RS06370	COG0740	serine-type endopeptidase activity
TF3313_RS06375	COG0544	peptidyl-prolyl cis-trans isomerase activity
TF3313_RS06405	COG4206	TonB-dependent receptor
TF3313_RS06410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TF3313_RS06430	COG0756	dUTP diphosphatase activity
TF3313_RS06450	COG4771	TonB-dependent receptor
TF3313_RS06465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TF3313_RS06485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TF3313_RS06495	COG0124	histidyl-tRNA synthetase
TF3313_RS06500	COG1404	Belongs to the peptidase S8 family
TF3313_RS06520	COG0551	DNA topoisomerase type I activity
TF3313_RS06520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TF3313_RS06525	COG1595	DNA-templated transcription, initiation
TF3313_RS06535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TF3313_RS06540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TF3313_RS06545	COG0049	tRNA binding
TF3313_RS06550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TF3313_RS06555	COG0051	transcription antitermination factor activity, RNA binding
TF3313_RS06560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TF3313_RS06565	COG0088	Forms part of the polypeptide exit tunnel
TF3313_RS06570	COG0089	rRNA binding
TF3313_RS06575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TF3313_RS06580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TF3313_RS06590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TF3313_RS06595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TF3313_RS06600	COG0255	Belongs to the universal ribosomal protein uL29 family
TF3313_RS06605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TF3313_RS06610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TF3313_RS06615	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TF3313_RS06620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TF3313_RS06625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TF3313_RS06630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TF3313_RS06635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TF3313_RS06640	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TF3313_RS06645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TF3313_RS06650	COG0200	Binds to the 23S rRNA
TF3313_RS06655	COG0201	protein transport
TF3313_RS06665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TF3313_RS06670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TF3313_RS06675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TF3313_RS06680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TF3313_RS06685	COG0202	RNA polymerase activity
TF3313_RS06690	COG0203	ribosomal protein L17
TF3313_RS06695	COG1127	ABC transporter
TF3313_RS06700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TF3313_RS06710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TF3313_RS06715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TF3313_RS06760	COG0366	Alpha amylase catalytic
TF3313_RS06765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TF3313_RS06775	COG0482	sulfurtransferase activity
TF3313_RS06790	COG4771	TonB-dependent receptor
TF3313_RS06820	COG1943	Transposase
TF3313_RS06850	COG0428	transporter
TF3313_RS06860	COG2226	methyltransferase
TF3313_RS06865	COG2226	methyltransferase
TF3313_RS06880	COG2226	methyltransferase
TF3313_RS06900	COG1132	(ABC) transporter
TF3313_RS06910	COG1132	(ABC) transporter
TF3313_RS06915	COG2066	Belongs to the glutaminase family
TF3313_RS06930	COG0196	riboflavin kinase activity
TF3313_RS06955	COG5492	domain, Protein
TF3313_RS06960	COG0641	radical SAM
TF3313_RS06970	COG1053	succinate dehydrogenase
TF3313_RS06980	COG0018	arginyl-trna synthetase
TF3313_RS06990	COG0525	valine-tRNA ligase activity
TF3313_RS07020	COG1242	4 iron, 4 sulfur cluster binding
TF3313_RS07040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TF3313_RS07065	COG0436	Aminotransferase
TF3313_RS07070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TF3313_RS07070	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TF3313_RS07085	COG0779	Required for maturation of 30S ribosomal subunits
TF3313_RS07090	COG0195	Participates in both transcription termination and antitermination
TF3313_RS07090	COG2251	uridine kinase activity
TF3313_RS07095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TF3313_RS07105	COG0719	Fe-S assembly protein
TF3313_RS07110	COG0396	ATPase activity
TF3313_RS07115	COG0719	Fe-S assembly protein
TF3313_RS07135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TF3313_RS07140	COG0436	Aminotransferase
TF3313_RS07165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TF3313_RS07175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TF3313_RS07180	COG2166	iron-sulfur cluster assembly
TF3313_RS07190	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TF3313_RS07195	COG0187	DNA topoisomerase II activity
TF3313_RS07200	COG2274	protein secretion by the type I secretion system
TF3313_RS07230	COG1216	Glycosyl transferase, family 2
TF3313_RS07230	COG0463	Glycosyl transferase, family 2
TF3313_RS07275	COG0268	Binds directly to 16S ribosomal RNA
TF3313_RS07290	COG1629	transport
TF3313_RS07290	COG4206	TonB-dependent receptor
TF3313_RS07300	COG4771	TonB-dependent receptor
TF3313_RS07310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TF3313_RS07320	COG3118	belongs to the thioredoxin family
TF3313_RS07350	COG0228	four-way junction DNA binding
TF3313_RS07365	COG0514	ATP-dependent DNA helicase (RecQ)
TF3313_RS07370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TF3313_RS07370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TF3313_RS07380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TF3313_RS07395	COG1253	flavin adenine dinucleotide binding
TF3313_RS07400	COG1760	l-serine dehydratase
TF3313_RS07405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TF3313_RS07410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TF3313_RS07415	COG0612	Peptidase, M16
TF3313_RS07450	COG1940	carbohydrate kinase activity
TF3313_RS07500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TF3313_RS07505	COG0674	pyruvate-flavodoxin oxidoreductase activity
TF3313_RS07505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TF3313_RS07510	COG1013	pyruvate-flavodoxin oxidoreductase activity
TF3313_RS07515	COG2177	Part of the ABC transporter FtsEX involved in
TF3313_RS07525	COG1968	undecaprenyl-diphosphatase activity
TF3313_RS07530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TF3313_RS07535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TF3313_RS07540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TF3313_RS07580	COG1595	DNA-templated transcription, initiation
TF3313_RS07595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TF3313_RS07600	COG1151	hydroxylamine reductase activity
TF3313_RS07605	COG1217	gtp-binding protein TYPA
TF3313_RS07610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TF3313_RS07615	COG1509	lysine 2,3-aminomutase activity
TF3313_RS07635	COG1271	oxidase subunit
TF3313_RS07645	COG1595	DNA-templated transcription, initiation
TF3313_RS07655	COG1629	transport
TF3313_RS07665	COG0673	inositol 2-dehydrogenase activity
TF3313_RS07680	COG0612	Peptidase, M16
TF3313_RS07685	COG0038	chloride channel
TF3313_RS07690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TF3313_RS07695	COG0009	L-threonylcarbamoyladenylate synthase
TF3313_RS07705	COG0363	glucosamine-6-phosphate deaminase activity
TF3313_RS07715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TF3313_RS07715	COG0426	domain, Protein
TF3313_RS07720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TF3313_RS07725	COG0673	inositol 2-dehydrogenase activity
TF3313_RS07730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TF3313_RS07735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TF3313_RS07740	COG0137	argininosuccinate synthase activity
TF3313_RS07750	COG1438	arginine binding
TF3313_RS07760	COG2211	Major facilitator Superfamily
TF3313_RS07765	COG1032	radical SAM domain protein
TF3313_RS07780	COG1131	(ABC) transporter
TF3313_RS07795	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TF3313_RS07800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TF3313_RS07805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TF3313_RS07810	COG0742	ribosomal rna small subunit methyltransferase
TF3313_RS07835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TF3313_RS07845	COG1011	Hydrolase
TF3313_RS07850	COG1492	cobalamin metabolic process
TF3313_RS07855	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TF3313_RS07860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TF3313_RS07865	COG0251	oxidation-reduction process
TF3313_RS07875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TF3313_RS07880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TF3313_RS07895	COG3209	COG3209 Rhs family protein
TF3313_RS07905	COG3209	COG3209 Rhs family protein
TF3313_RS07970	COG0336	Belongs to the RNA methyltransferase TrmD family
TF3313_RS07975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TF3313_RS07975	COG0072	phenylalanine-tRNA ligase activity
TF3313_RS07980	COG0217	transcriptional regulatory protein
TF3313_RS08005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TF3313_RS08010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TF3313_RS08015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TF3313_RS08020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TF3313_RS08025	COG0791	NLP P60 protein
TF3313_RS08030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TF3313_RS08035	COG1408	metallophosphoesterase
TF3313_RS08060	COG4139	cobalamin transport
TF3313_RS08080	COG0632	four-way junction helicase activity
TF3313_RS08090	COG1074	ATP-dependent DNA helicase activity
TF3313_RS08095	COG0688	phosphatidylethanolamine metabolic process
TF3313_RS08100	COG1183	phosphatidylcholine synthase activity
TF3313_RS08110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TF3313_RS08145	COG0737	Belongs to the 5'-nucleotidase family
TF3313_RS08165	COG0745	RESPONSE REGULATOR receiver
TF3313_RS08165	COG2205	protein histidine kinase activity
TF3313_RS08165	COG3292	Two component regulator propeller
TF3313_RS08170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TF3313_RS08175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TF3313_RS08190	COG1381	Involved in DNA repair and RecF pathway recombination
TF3313_RS08200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TF3313_RS08210	COG2843	Capsule synthesis protein
TF3313_RS08215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
TF3313_RS08220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TF3313_RS08225	COG4974	Belongs to the 'phage' integrase family
TF3313_RS08245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TF3313_RS08260	COG0250	Participates in transcription elongation, termination and antitermination
TF3313_RS08265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TF3313_RS08270	COG0081	regulation of translation
TF3313_RS08275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TF3313_RS08280	COG0222	ribosome binding
TF3313_RS08285	COG0085	RNA polymerase activity
TF3313_RS08290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TF3313_RS08295	COG0433	COG0433 Predicted ATPase
TF3313_RS08305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TF3313_RS08310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TF3313_RS08315	COG4948	Mandelate Racemase Muconate Lactonizing
TF3313_RS08330	COG4974	Belongs to the 'phage' integrase family
TF3313_RS08345	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TF3313_RS08350	COG4804	nuclease activity
TF3313_RS08355	COG0732	type I restriction modification DNA specificity domain
TF3313_RS08375	COG0732	type I restriction modification DNA specificity domain
TF3313_RS08425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TF3313_RS08495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TF3313_RS08545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TF3313_RS08590	COG4771	TonB-dependent receptor
TF3313_RS08595	COG0702	epimerase
TF3313_RS08605	COG4221	oxidoreductase activity
TF3313_RS08620	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TF3313_RS08625	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TF3313_RS08625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TF3313_RS08630	COG1368	sulfuric ester hydrolase activity
TF3313_RS08635	COG1047	Peptidyl-prolyl cis-trans
TF3313_RS08640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TF3313_RS08645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS08660	COG0750	zinc metalloprotease
TF3313_RS08665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TF3313_RS08670	COG4942	peptidase
TF3313_RS08675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TF3313_RS08685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TF3313_RS08690	COG2183	response to ionizing radiation
TF3313_RS08725	COG0516	GMP reductase activity
TF3313_RS08730	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TF3313_RS08730	COG1918	ferrous iron import across plasma membrane
TF3313_RS08740	COG3275	phosphorelay sensor kinase activity
TF3313_RS08745	COG3279	Response regulator of the LytR AlgR family
TF3313_RS08800	COG4974	Belongs to the 'phage' integrase family
TF3313_RS08805	COG0582	viral genome integration into host DNA
TF3313_RS08825	COG0148	phosphopyruvate hydratase activity
TF3313_RS08835	COG0716	FMN binding
TF3313_RS08860	COG4771	TonB-dependent receptor
TF3313_RS08865	COG4771	TonB-dependent receptor
TF3313_RS08880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TF3313_RS08885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TF3313_RS08905	COG3876	Protein conserved in bacteria
TF3313_RS08915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TF3313_RS08920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TF3313_RS08925	COG0052	Belongs to the universal ribosomal protein uS2 family
TF3313_RS08930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TF3313_RS08975	COG1629	transport
TF3313_RS08980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TF3313_RS08995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TF3313_RS08995	COG4651	solute:proton antiporter activity
TF3313_RS09005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TF3313_RS09025	COG1418	mRNA catabolic process
TF3313_RS09030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TF3313_RS09035	COG0488	(ABC) transporter
TF3313_RS09055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TF3313_RS09085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TF3313_RS09100	COG3876	Protein conserved in bacteria
TF3313_RS09105	COG2871	sodium ion transport
TF3313_RS09110	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
TF3313_RS09115	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
TF3313_RS09120	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
TF3313_RS09125	COG1805	sodium ion transport
TF3313_RS09130	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
TF3313_RS09145	COG0739	heme binding
TF3313_RS09150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TF3313_RS09155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TF3313_RS09160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TF3313_RS09165	COG0563	adenylate kinase activity
TF3313_RS09175	COG3845	ABC transporter
TF3313_RS09185	COG0346	lactoylglutathione lyase activity
TF3313_RS09200	COG0463	Glycosyl transferase, family 2
TF3313_RS09210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TF3313_RS09215	COG4452	Inner membrane protein CreD
TF3313_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
TF3313_RS09255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TF3313_RS09260	COG1309	transcriptional regulator
TF3313_RS09290	COG2885	chlorophyll binding
TF3313_RS09295	COG0542	response to heat
TF3313_RS09340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TF3313_RS09350	COG2271	Major facilitator Superfamily
TF3313_RS09355	COG4206	TonB-dependent receptor
TF3313_RS09355	COG1629	transport
TF3313_RS09360	COG0702	epimerase
TF3313_RS09370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
TF3313_RS09400	COG4822	anaerobic cobalamin biosynthetic process
TF3313_RS09415	COG4771	TonB-dependent receptor
TF3313_RS09420	COG1477	protein flavinylation
TF3313_RS09435	COG1480	7TM receptor with intracellular HD hydrolase
TF3313_RS09565	COG1072	(Pantothenic acid kinase))
TF3313_RS09585	COG1131	(ABC) transporter
TF3313_RS09590	COG1131	(ABC) transporter
TF3313_RS09595	COG0842	Transport permease protein
TF3313_RS09620	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
TF3313_RS09625	COG4206	TonB-dependent receptor
TF3313_RS09625	COG1629	transport
TF3313_RS09630	COG1082	Xylose isomerase domain protein TIM barrel
TF3313_RS09640	COG0343	queuine tRNA-ribosyltransferase activity
TF3313_RS09650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TF3313_RS09660	COG1773	rubredoxin
TF3313_RS09665	COG0583	DNA-binding transcription factor activity
TF3313_RS09675	COG0668	transmembrane transport
TF3313_RS09680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TF3313_RS09690	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TF3313_RS09695	COG4771	TonB-dependent receptor
TF3313_RS09705	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
TF3313_RS09710	COG4677	pectinesterase activity
TF3313_RS09715	COG3119	arylsulfatase activity
TF3313_RS09730	COG1028	Short-chain dehydrogenase reductase Sdr
TF3313_RS09740	COG2271	Major facilitator Superfamily
TF3313_RS09825	COG1570	exodeoxyribonuclease VII activity
TF3313_RS09835	COG2502	aspartate--ammonia ligase
TF3313_RS09845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TF3313_RS09845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TF3313_RS09850	COG1752	Esterase of the alpha-beta hydrolase superfamily
TF3313_RS09860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TF3313_RS09915	COG3177	Filamentation induced by cAMP protein fic
TF3313_RS09930	COG1353	crispr-associated protein
TF3313_RS09940	COG1337	RAMP superfamily
TF3313_RS10085	COG3617	BRO family, N-terminal domain
TF3313_RS10200	COG1518	maintenance of DNA repeat elements
TF3313_RS10205	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TF3313_RS10235	COG1528	Iron-storage protein
TF3313_RS10240	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TF3313_RS10255	COG0776	regulation of translation
TF3313_RS10260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TF3313_RS10270	COG1640	4-alpha-glucanotransferase
TF3313_RS10290	COG4589	Belongs to the CDS family
TF3313_RS10295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TF3313_RS10300	COG0799	negative regulation of ribosome biogenesis
TF3313_RS10330	COG4206	TonB-dependent receptor
TF3313_RS10330	COG1629	transport
TF3313_RS10350	COG0285	dihydrofolate synthase activity
TF3313_RS10355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TF3313_RS10365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TF3313_RS10415	COG0497	DNA recombination
TF3313_RS10420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TF3313_RS10425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TF3313_RS10430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TF3313_RS10435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TF3313_RS10440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TF3313_RS10450	COG2195	Cleaves the N-terminal amino acid of tripeptides
TF3313_RS10465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TF3313_RS10470	COG1979	alcohol dehydrogenase
TF3313_RS10490	COG3250	beta-galactosidase activity
TF3313_RS10495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TF3313_RS10510	COG0470	DNA polymerase III
TF3313_RS10515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TF3313_RS10525	COG0534	Mate efflux family protein
TF3313_RS10530	COG4771	TonB-dependent receptor
TF3313_RS10565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TF3313_RS10570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TF3313_RS10575	COG1748	Saccharopine dehydrogenase
TF3313_RS10590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TF3313_RS10595	COG1216	Glycosyl transferase, family 2
TF3313_RS10660	COG3209	COG3209 Rhs family protein
TF3313_RS10670	COG3209	COG3209 Rhs family protein
TF3313_RS10715	COG4206	TonB-dependent receptor
TF3313_RS10715	COG1629	transport
TF3313_RS10745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TF3313_RS10755	COG0739	heme binding
TF3313_RS10770	COG0149	triose-phosphate isomerase activity
TF3313_RS10780	COG0302	gtp cyclohydrolase
TF3313_RS10785	COG0009	L-threonylcarbamoyladenylate synthase
TF3313_RS10800	COG4690	dipeptidase activity
TF3313_RS10825	COG0545	Peptidyl-prolyl cis-trans isomerase
TF3313_RS10830	COG0545	Peptidyl-prolyl cis-trans isomerase
TF3313_RS10875	COG1629	transport
TF3313_RS10875	COG4206	TonB-dependent receptor
TF3313_RS10890	COG0823	Involved in the tonB-independent uptake of proteins
TF3313_RS10900	COG0463	Glycosyl transferase, family 2
TF3313_RS10905	COG1649	PFAM Uncharacterised BCR, COG1649
TF3313_RS10910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TF3313_RS10920	COG0860	N-Acetylmuramoyl-L-alanine amidase
TF3313_RS10920	COG1388	LysM domain
TF3313_RS10930	COG0741	lytic transglycosylase activity
TF3313_RS10930	COG1388	LysM domain
TF3313_RS10935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TF3313_RS10945	COG1739	Uncharacterized protein family UPF0029
TF3313_RS10955	COG0006	proline dipeptidase activity
TF3313_RS10960	COG1785	Belongs to the alkaline phosphatase family
TF3313_RS10980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS10980	COG5549	protein import
TF3313_RS10990	COG5549	protein import
TF3313_RS10990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS10995	COG5549	protein import
TF3313_RS10995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS11005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TF3313_RS11005	COG5549	protein import
TF3313_RS11035	COG1649	PFAM Uncharacterised BCR, COG1649
TF3313_RS11045	COG0492	ferredoxin-NADP+ reductase activity
TF3313_RS11055	COG1674	ftsk spoiiie
TF3313_RS11060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TF3313_RS11065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TF3313_RS11075	COG0037	tRNA processing
TF3313_RS11095	COG2197	response regulator
TF3313_RS11100	COG0569	domain protein
TF3313_RS11100	COG2985	domain, Protein
TF3313_RS11130	COG1620	l-lactate permease
TF3313_RS11135	COG1556	Lactate utilization protein
TF3313_RS11140	COG1139	Iron-sulfur cluster binding protein
TF3313_RS11180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TF3313_RS11185	COG0321	lipoyl(octanoyl) transferase activity
TF3313_RS11195	COG1774	PSP1 C-terminal conserved region
TF3313_RS11200	COG0156	8-amino-7-oxononanoate synthase activity
TF3313_RS11205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TF3313_RS11215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TF3313_RS11220	COG0402	S-adenosylhomocysteine deaminase activity
TF3313_RS11265	COG4206	TonB-dependent receptor
TF3313_RS11265	COG1629	transport
TF3313_RS11270	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
TF3313_RS11280	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TF3313_RS11285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TF3313_RS11285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TF3313_RS11290	COG0488	(ABC) transporter
TF3313_RS11300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
TF3313_RS11305	COG0706	membrane insertase activity
TF3313_RS11310	COG0504	CTP synthase activity
TF3313_RS11315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TF3313_RS11330	COG1245	4Fe-4S binding domain
TF3313_RS11330	COG2878	Part of a membrane complex involved in electron transport
TF3313_RS11335	COG4656	Part of a membrane complex involved in electron transport
TF3313_RS11340	COG4658	electron transport chain
TF3313_RS11345	COG4659	FMN binding
TF3313_RS11350	COG4660	Part of a membrane complex involved in electron transport
TF3313_RS11355	COG4657	Part of a membrane complex involved in electron transport
TF3313_RS11385	COG2252	PERMEase
TF3313_RS11405	COG3119	arylsulfatase activity
TF3313_RS11415	COG2096	Adenosyltransferase
TF3313_RS11435	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TF3313_RS11460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TF3313_RS11505	COG1629	transport
TF3313_RS11505	COG4206	TonB-dependent receptor
TF3313_RS11530	COG2115	Belongs to the xylose isomerase family
TF3313_RS11535	COG2814	Major facilitator Superfamily
TF3313_RS11535	COG0477	Major facilitator Superfamily
TF3313_RS11555	COG4771	TonB-dependent receptor
TF3313_RS11620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TF3313_RS11625	COG1032	radical SAM domain protein
TF3313_RS11630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TF3313_RS11635	COG0513	Belongs to the DEAD box helicase family
TF3313_RS11690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TF3313_RS11695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TF3313_RS11700	COG1663	tetraacyldisaccharide 4'-kinase activity
TF3313_RS11705	COG0616	signal peptide processing
TF3313_RS11710	COG0534	Mate efflux family protein
TF3313_RS11720	COG1505	serine-type exopeptidase activity
TF3313_RS11730	COG3292	Two component regulator propeller
TF3313_RS11730	COG0745	RESPONSE REGULATOR receiver
TF3313_RS11730	COG2205	protein histidine kinase activity
TF3313_RS11780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TF3313_RS11780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TF3313_RS11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TF3313_RS11790	COG0357	Ribosomal RNA small subunit methyltransferase G
TF3313_RS11800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TF3313_RS11820	COG0671	phosphoesterase, PA-phosphatase related
TF3313_RS11840	COG2304	oxidoreductase activity
TF3313_RS11845	COG2304	oxidoreductase activity
TF3313_RS11860	COG0714	Associated with various cellular activities
TF3313_RS11870	COG0776	regulation of translation
TF3313_RS11875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TF3313_RS11880	COG0552	protein localization to endoplasmic reticulum
TF3313_RS11925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TF3313_RS11945	COG1530	ribonuclease E activity
TF3313_RS11950	COG0776	regulation of translation
TF3313_RS11960	COG0629	single-stranded DNA binding
TF3313_RS11995	COG0702	epimerase
TF3313_RS12000	COG1629	transport
TF3313_RS12015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TF3313_RS12020	COG0671	phosphoesterase, PA-phosphatase related
TF3313_RS12040	COG0673	inositol 2-dehydrogenase activity
TF3313_RS12045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TF3313_RS12050	COG2195	Cleaves the N-terminal amino acid of tripeptides
TF3313_RS12060	COG0463	Glycosyl transferase, family 2
TF3313_RS12075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TF3313_RS12085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TF3313_RS12095	COG1611	Belongs to the LOG family
TF3313_RS12100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TF3313_RS12115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TF3313_RS12135	COG3537	Alpha-1,2-mannosidase
TF3313_RS12140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TF3313_RS12145	COG2226	methyltransferase
TF3313_RS12150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TF3313_RS12165	COG0006	proline dipeptidase activity
TF3313_RS12215	COG3250	beta-galactosidase activity
TF3313_RS12225	COG0481	GTPase activity
TF3313_RS12230	COG4771	TonB-dependent receptor
TF3313_RS12235	COG0702	epimerase
TF3313_RS12240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
TF3313_RS12245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TF3313_RS12250	COG0574	Belongs to the PEP-utilizing enzyme family
TF3313_RS12250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TF3313_RS12295	COG1629	transport
TF3313_RS12315	COG0156	8-amino-7-oxononanoate synthase activity
TF3313_RS12340	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TF3313_RS12360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TF3313_RS12390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TF3313_RS12395	COG0489	protein tyrosine kinase activity
TF3313_RS12405	COG0793	Belongs to the peptidase S41A family
TF3313_RS12410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TF3313_RS12440	COG2194	sulfuric ester hydrolase activity
TF3313_RS12480	COG0300	oxidoreductase activity
TF3313_RS12490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TF3313_RS12500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TF3313_RS12505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TF3313_RS12530	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
TF3313_RS12535	COG0653	protein targeting
TF3313_RS12540	COG3292	Two component regulator propeller
TF3313_RS12540	COG2205	protein histidine kinase activity
TF3313_RS12540	COG0745	RESPONSE REGULATOR receiver
TF3313_RS12550	COG0242	peptide deformylase activity
TF3313_RS12555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TF3313_RS12560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TF3313_RS12570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TF3313_RS12575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TF3313_RS12585	COG0436	Aminotransferase
TF3313_RS12595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TF3313_RS12610	COG2873	o-acetylhomoserine
TF3313_RS12615	COG1668	transmembrane transport
TF3313_RS12620	COG0358	DNA primase activity
TF3313_RS12680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TF3313_RS12695	COG1506	peptidase
TF3313_RS12695	COG0823	Involved in the tonB-independent uptake of proteins
TF3313_RS12700	COG0424	maF-like protein
TF3313_RS12705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TF3313_RS12720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TF3313_RS12725	COG0193	aminoacyl-tRNA hydrolase activity
TF3313_RS12730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TF3313_RS12795	COG0681	Belongs to the peptidase S26 family
TF3313_RS12800	COG1132	(ABC) transporter
TF3313_RS12845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TF3313_RS12880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TF3313_RS12885	COG2268	Band 7 protein
TF3313_RS12905	COG0490	domain, Protein
TF3313_RS12905	COG2985	domain, Protein
TF3313_RS12980	COG1295	ribonuclease BN
TF3313_RS12985	COG0527	aspartate kinase activity
TF3313_RS12985	COG0460	homoserine dehydrogenase
TF3313_RS12990	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TF3313_RS13000	COG1242	4 iron, 4 sulfur cluster binding
TF3313_RS13015	COG0363	glucosamine-6-phosphate deaminase activity
TF3313_RS13020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TF3313_RS13050	COG2832	Protein of unknown function (DUF454)
TF3313_RS13065	COG0778	Nitroreductase
TF3313_RS13070	COG0318	PFAM AMP-dependent synthetase and ligase
TF3313_RS13105	COG1309	transcriptional regulator
TF3313_RS13155	COG1373	ATPase (AAA superfamily
TF3313_RS13180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TF3313_RS13180	COG0731	radical SAM domain protein
TF3313_RS13270	COG0740	serine-type endopeptidase activity
TF3313_RS13290	COG4383	Mu-like prophage protein gp29
TF3313_RS13505	COG1192	Involved in chromosome partitioning
TF3313_RS13570	COG0739	heme binding
TF3313_RS13585	COG1373	ATPase (AAA superfamily
TF3313_RS13665	COG0564	pseudouridine synthase activity
TF3313_RS13670	COG1181	Belongs to the D-alanine--D-alanine ligase family
TF3313_RS13680	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TF3313_RS13685	COG0179	Fumarylacetoacetate (FAA) hydrolase
TF3313_RS13705	COG0793	Belongs to the peptidase S41A family
TF3313_RS13705	COG4946	Tricorn protease homolog
TF3313_RS13710	COG3250	beta-galactosidase activity
TF3313_RS13720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TF3313_RS13745	COG0058	SHG alpha-glucan phosphorylase activity
TF3313_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
TF3313_RS13775	COG3022	response to hydroperoxide
TF3313_RS13790	COG1061	Type III restriction enzyme res subunit
TF3313_RS13795	COG1629	transport
TF3313_RS13800	COG0702	epimerase
TF3313_RS13830	COG4771	TonB-dependent receptor
TF3313_RS13855	COG0254	rRNA binding
TF3313_RS13860	COG0191	fructose-bisphosphate aldolase activity
TF3313_RS13865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TF3313_RS13885	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TF3313_RS13895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TF3313_RS13910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TF3313_RS13915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TF3313_RS13920	COG0805	protein transport
TF3313_RS13925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TF3313_RS13930	COG0305	Participates in initiation and elongation during chromosome replication
TF3313_RS13940	COG0488	(ABC) transporter
TF3313_RS13945	COG0138	bifunctional purine biosynthesis protein purh
TF3313_RS13970	COG0772	Belongs to the SEDS family
TF3313_RS13975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TF3313_RS13980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TF3313_RS13985	COG0166	Belongs to the GPI family
TF3313_RS13995	COG0360	Binds together with S18 to 16S ribosomal RNA
TF3313_RS14000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TF3313_RS14005	COG0359	binds to the 23S rRNA
TF3313_RS14010	COG0860	N-Acetylmuramoyl-L-alanine amidase