locus-tag	class	description
BCB71_RS00040	COG4865	methylaspartate mutase activity
BCB71_RS00050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCB71_RS00065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCB71_RS00065	COG4651	solute:proton antiporter activity
BCB71_RS00075	COG0251	oxidation-reduction process
BCB71_RS00120	COG1408	metallophosphoesterase
BCB71_RS00125	COG1408	metallophosphoesterase
BCB71_RS00130	COG4139	cobalamin transport
BCB71_RS00140	COG0519	Catalyzes the synthesis of GMP from XMP
BCB71_RS00145	COG2323	membrane
BCB71_RS00150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCB71_RS00175	COG0793	Belongs to the peptidase S41A family
BCB71_RS00205	COG1245	4Fe-4S binding domain
BCB71_RS00205	COG2878	Part of a membrane complex involved in electron transport
BCB71_RS00210	COG4656	Part of a membrane complex involved in electron transport
BCB71_RS00215	COG4658	electron transport chain
BCB71_RS00220	COG4659	FMN binding
BCB71_RS00225	COG4660	Part of a membrane complex involved in electron transport
BCB71_RS00230	COG4657	Part of a membrane complex involved in electron transport
BCB71_RS00235	COG0656	L-ascorbic acid biosynthetic process
BCB71_RS00240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCB71_RS00250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCB71_RS00255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCB71_RS00255	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCB71_RS00260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCB71_RS00270	COG2966	Psort location CytoplasmicMembrane, score
BCB71_RS00290	COG1733	regulation of RNA biosynthetic process
BCB71_RS00300	COG1704	LemA family
BCB71_RS00320	COG0616	signal peptide processing
BCB71_RS00325	COG1663	tetraacyldisaccharide 4'-kinase activity
BCB71_RS00330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCB71_RS00335	COG0328	RNA-DNA hybrid ribonuclease activity
BCB71_RS00335	COG3341	Caulimovirus viroplasmin
BCB71_RS00340	COG0513	Belongs to the DEAD box helicase family
BCB71_RS00350	COG0517	IMP dehydrogenase activity
BCB71_RS00350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCB71_RS00390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCB71_RS00410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCB71_RS00415	COG0193	aminoacyl-tRNA hydrolase activity
BCB71_RS00420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCB71_RS00430	COG0302	gtp cyclohydrolase
BCB71_RS00440	COG0149	triose-phosphate isomerase activity
BCB71_RS00455	COG0739	heme binding
BCB71_RS00465	COG0066	3-isopropylmalate dehydratase activity
BCB71_RS00470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCB71_RS00475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCB71_RS00480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCB71_RS00490	COG0440	acetolactate synthase activity
BCB71_RS00495	COG0028	Belongs to the TPP enzyme family
BCB71_RS00500	COG0129	dihydroxy-acid dehydratase activity
BCB71_RS00510	COG0737	Belongs to the 5'-nucleotidase family
BCB71_RS00520	COG1028	Short-chain dehydrogenase reductase Sdr
BCB71_RS00525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCB71_RS00550	COG0116	Belongs to the methyltransferase superfamily
BCB71_RS00570	COG1629	transport
BCB71_RS00570	COG4206	TonB-dependent receptor
BCB71_RS00580	COG3940	Belongs to the glycosyl hydrolase 43 family
BCB71_RS00600	COG0545	Peptidyl-prolyl cis-trans isomerase
BCB71_RS00605	COG0545	Peptidyl-prolyl cis-trans isomerase
BCB71_RS00610	COG2204	response regulator
BCB71_RS00625	COG0366	Alpha amylase catalytic
BCB71_RS00630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCB71_RS00645	COG0525	valine-tRNA ligase activity
BCB71_RS00680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCB71_RS00685	COG1519	Transferase
BCB71_RS00695	COG2843	Capsule synthesis protein
BCB71_RS00700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCB71_RS00705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCB71_RS00710	COG4974	Belongs to the 'phage' integrase family
BCB71_RS00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCB71_RS00740	COG0250	Participates in transcription elongation, termination and antitermination
BCB71_RS00745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCB71_RS00750	COG0081	regulation of translation
BCB71_RS00755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCB71_RS00760	COG0222	ribosome binding
BCB71_RS00765	COG0085	RNA polymerase activity
BCB71_RS00775	COG0433	COG0433 Predicted ATPase
BCB71_RS00785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCB71_RS00790	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCB71_RS00790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCB71_RS00895	COG3344	reverse transcriptase
BCB71_RS00950	COG4974	Belongs to the 'phage' integrase family
BCB71_RS00965	COG4804	nuclease activity
BCB71_RS00970	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCB71_RS01025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCB71_RS01045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCB71_RS01070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCB71_RS01120	COG1012	belongs to the aldehyde dehydrogenase family
BCB71_RS01125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCB71_RS01130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCB71_RS01145	COG1773	rubredoxin
BCB71_RS01150	COG0318	PFAM AMP-dependent synthetase and ligase
BCB71_RS01170	COG0702	epimerase
BCB71_RS01175	COG1629	transport
BCB71_RS01225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCB71_RS01235	COG0228	four-way junction DNA binding
BCB71_RS01255	COG0424	maF-like protein
BCB71_RS01260	COG0823	Involved in the tonB-independent uptake of proteins
BCB71_RS01260	COG1506	peptidase
BCB71_RS01310	COG1132	(ABC) transporter
BCB71_RS01315	COG1132	(ABC) transporter
BCB71_RS01335	COG4974	Belongs to the 'phage' integrase family
BCB71_RS01340	COG4974	Belongs to the 'phage' integrase family
BCB71_RS01345	COG1309	transcriptional regulator
BCB71_RS01350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCB71_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
BCB71_RS01365	COG0564	pseudouridine synthase activity
BCB71_RS01370	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BCB71_RS01385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCB71_RS01435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCB71_RS01460	COG1595	DNA-templated transcription, initiation
BCB71_RS01475	COG0402	S-adenosylhomocysteine deaminase activity
BCB71_RS01535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCB71_RS01550	COG0813	purine-nucleoside phosphorylase activity
BCB71_RS01570	COG2843	Capsule synthesis protein
BCB71_RS01585	COG1132	(ABC) transporter
BCB71_RS01595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCB71_RS01620	COG3645	SOS response
BCB71_RS01625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCB71_RS01645	COG3177	Filamentation induced by cAMP protein fic
BCB71_RS01690	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCB71_RS01695	COG1047	Peptidyl-prolyl cis-trans
BCB71_RS01700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCB71_RS01705	COG3409	Peptidoglycan-binding domain 1 protein
BCB71_RS01705	COG0793	Belongs to the peptidase S41A family
BCB71_RS01710	COG0156	8-amino-7-oxononanoate synthase activity
BCB71_RS01715	COG1774	PSP1 C-terminal conserved region
BCB71_RS01725	COG0138	bifunctional purine biosynthesis protein purh
BCB71_RS01745	COG0768	penicillin binding
BCB71_RS01750	COG0772	Belongs to the SEDS family
BCB71_RS01765	COG0575	Belongs to the CDS family
BCB71_RS01770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCB71_RS01775	COG0799	negative regulation of ribosome biogenesis
BCB71_RS01790	COG1151	hydroxylamine reductase activity
BCB71_RS01795	COG0783	Belongs to the Dps family
BCB71_RS01800	COG0463	Glycosyl transferase, family 2
BCB71_RS01815	COG0307	riboflavin synthase, alpha
BCB71_RS01820	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BCB71_RS01840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCB71_RS01855	COG4974	Belongs to the 'phage' integrase family
BCB71_RS01860	COG4974	Belongs to the 'phage' integrase family
BCB71_RS01875	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCB71_RS01890	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCB71_RS01940	COG1115	amino acid carrier protein
BCB71_RS01945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCB71_RS01990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCB71_RS01995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCB71_RS02020	COG0194	GDP metabolic process
BCB71_RS02025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCB71_RS02055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCB71_RS02060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCB71_RS02065	COG0442	prolyl-tRNA aminoacylation
BCB71_RS02090	COG0180	Tryptophanyl-tRNA synthetase
BCB71_RS02110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BCB71_RS02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCB71_RS02125	COG0497	DNA recombination
BCB71_RS02170	COG2217	Heavy metal translocating P-type atpase
BCB71_RS02175	COG4974	Belongs to the 'phage' integrase family
BCB71_RS02180	COG0582	viral genome integration into host DNA
BCB71_RS02200	COG0592	DNA-directed DNA polymerase activity
BCB71_RS02210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCB71_RS02215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCB71_RS02240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BCB71_RS02245	COG0346	lactoylglutathione lyase activity
BCB71_RS02260	COG3015	lipoprotein NlpE involved in copper resistance
BCB71_RS02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCB71_RS02275	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BCB71_RS02285	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCB71_RS02290	COG0564	pseudouridine synthase activity
BCB71_RS02300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCB71_RS02305	COG0671	phosphoesterase, PA-phosphatase related
BCB71_RS02315	COG0217	transcriptional regulatory protein
BCB71_RS02350	COG0242	peptide deformylase activity
BCB71_RS02355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCB71_RS02370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCB71_RS02405	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCB71_RS02415	COG2027	D-alanyl-D-alanine carboxypeptidase
BCB71_RS02450	COG0793	Belongs to the peptidase S41A family
BCB71_RS02455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCB71_RS02470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCB71_RS02480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCB71_RS02485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCB71_RS02490	COG0811	peptide transport
BCB71_RS02495	COG0848	biopolymer transport protein
BCB71_RS02505	COG0693	protein deglycase activity
BCB71_RS02530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCB71_RS02535	COG1649	PFAM Uncharacterised BCR, COG1649
BCB71_RS02545	COG1022	Amp-dependent synthetase and ligase
BCB71_RS02555	COG0750	zinc metalloprotease
BCB71_RS02560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCB71_RS02570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCB71_RS02575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCB71_RS02585	COG0668	transmembrane transport
BCB71_RS02590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCB71_RS02600	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BCB71_RS02605	COG0540	Belongs to the ATCase OTCase family
BCB71_RS02610	COG1970	mechanosensitive ion channel activity
BCB71_RS02620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCB71_RS02625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCB71_RS02650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCB71_RS02685	COG0363	glucosamine-6-phosphate deaminase activity
BCB71_RS02730	COG1131	(ABC) transporter
BCB71_RS02750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCB71_RS02765	COG1032	radical SAM domain protein
BCB71_RS02795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCB71_RS02800	COG2086	electron transfer activity
BCB71_RS02805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCB71_RS02810	COG0187	DNA topoisomerase II activity
BCB71_RS02820	COG0268	Binds directly to 16S ribosomal RNA
BCB71_RS02830	COG1739	Uncharacterized protein family UPF0029
BCB71_RS02845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCB71_RS02865	COG1114	Component of the transport system for branched-chain amino acids
BCB71_RS02870	COG0612	Peptidase, M16
BCB71_RS02875	COG4771	TonB-dependent receptor
BCB71_RS02895	COG3876	Protein conserved in bacteria
BCB71_RS02910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCB71_RS02910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCB71_RS02915	COG2890	protein-(glutamine-N5) methyltransferase activity
BCB71_RS02930	COG1160	GTP binding
BCB71_RS02935	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCB71_RS02940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCB71_RS02945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCB71_RS02955	COG1040	competence protein
BCB71_RS02980	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BCB71_RS02995	COG2205	protein histidine kinase activity
BCB71_RS03000	COG0745	RESPONSE REGULATOR receiver
BCB71_RS03020	COG0196	riboflavin kinase activity
BCB71_RS03035	COG4974	Belongs to the 'phage' integrase family
BCB71_RS03040	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCB71_RS03055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCB71_RS03065	COG1121	(ABC) transporter
BCB71_RS03075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCB71_RS03085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCB71_RS03095	COG1629	transport
BCB71_RS03095	COG4206	TonB-dependent receptor
BCB71_RS03100	COG0436	Aminotransferase
BCB71_RS03115	COG4974	Belongs to the 'phage' integrase family
BCB71_RS03205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCB71_RS03210	COG4771	TonB-dependent receptor
BCB71_RS03280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCB71_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCB71_RS03310	COG4206	TonB-dependent receptor
BCB71_RS03310	COG1629	transport
BCB71_RS03330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCB71_RS03355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCB71_RS03390	COG4771	TonB-dependent receptor
BCB71_RS03395	COG1575	Belongs to the MenA family. Type 1 subfamily
BCB71_RS03455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCB71_RS03465	COG0546	phosphoglycolate phosphatase activity
BCB71_RS03480	COG4771	TonB-dependent receptor
BCB71_RS03525	COG0561	phosphatase activity
BCB71_RS03530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCB71_RS03540	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCB71_RS03560	COG1228	amidohydrolase
BCB71_RS03570	COG3404	Formiminotransferase-cyclodeaminase
BCB71_RS03575	COG2986	histidine ammonia-lyase
BCB71_RS03585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BCB71_RS03600	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BCB71_RS03610	COG0716	FMN binding
BCB71_RS03620	COG0148	phosphopyruvate hydratase activity
BCB71_RS03625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCB71_RS03645	COG4822	anaerobic cobalamin biosynthetic process
BCB71_RS03650	COG4771	TonB-dependent receptor
BCB71_RS03655	COG4771	TonB-dependent receptor
BCB71_RS03665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCB71_RS03680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCB71_RS03685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCB71_RS03705	COG2873	o-acetylhomoserine
BCB71_RS03710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCB71_RS03715	COG0450	alkyl hydroperoxide reductase
BCB71_RS03725	COG3956	TIGRFAM MazG family protein
BCB71_RS03730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCB71_RS03745	COG1131	(ABC) transporter
BCB71_RS03750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCB71_RS03755	COG0563	adenylate kinase activity
BCB71_RS03760	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCB71_RS03770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCB71_RS03780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCB71_RS03800	COG0252	asparaginase activity
BCB71_RS03810	COG3059	membrane
BCB71_RS03835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCB71_RS03855	COG1295	ribonuclease BN
BCB71_RS03880	COG0756	dUTP diphosphatase activity
BCB71_RS03960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCB71_RS03960	COG5549	protein import
BCB71_RS04080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCB71_RS04080	COG1333	cytochrome c biogenesis protein
BCB71_RS04090	COG3292	Two component regulator propeller
BCB71_RS04090	COG2205	protein histidine kinase activity
BCB71_RS04090	COG0745	RESPONSE REGULATOR receiver
BCB71_RS04095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCB71_RS04100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCB71_RS04125	COG0776	regulation of translation
BCB71_RS04130	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCB71_RS04140	COG1678	Uncharacterized ACR, COG1678
BCB71_RS04150	COG3852	Histidine kinase
BCB71_RS04155	COG0039	L-malate dehydrogenase activity
BCB71_RS04160	COG1045	serine acetyltransferase
BCB71_RS04175	COG2096	Adenosyltransferase
BCB71_RS04190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCB71_RS04230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCB71_RS04235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCB71_RS04245	COG1830	Aldolase
BCB71_RS04250	COG0588	phosphoglycerate mutase activity
BCB71_RS04280	COG1082	Xylose isomerase domain protein TIM barrel
BCB71_RS04285	COG1629	transport
BCB71_RS04285	COG4206	TonB-dependent receptor
BCB71_RS04290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BCB71_RS04300	COG1058	Belongs to the CinA family
BCB71_RS04300	COG1546	Belongs to the CinA family
BCB71_RS04305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCB71_RS04310	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCB71_RS04315	COG0166	Belongs to the GPI family
BCB71_RS04320	COG0488	(ABC) transporter
BCB71_RS04330	COG0542	response to heat
BCB71_RS04340	COG4206	TonB-dependent receptor
BCB71_RS04340	COG1629	transport
BCB71_RS04355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCB71_RS04360	COG1233	COG1233 Phytoene dehydrogenase and related
BCB71_RS04370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCB71_RS04375	COG0463	Glycosyl transferase, family 2
BCB71_RS04380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCB71_RS04565	COG4383	Mu-like prophage protein gp29
BCB71_RS04590	COG3344	reverse transcriptase
BCB71_RS04600	COG0443	Heat shock 70 kDa protein
BCB71_RS04620	COG0475	glutathione-regulated potassium exporter activity
BCB71_RS04630	COG0702	epimerase
BCB71_RS04635	COG4771	TonB-dependent receptor
BCB71_RS04640	COG4974	Belongs to the 'phage' integrase family
BCB71_RS04645	COG4974	Belongs to the 'phage' integrase family
BCB71_RS04675	COG0714	Associated with various cellular activities
BCB71_RS04695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCB71_RS04700	COG1482	cell wall glycoprotein biosynthetic process
BCB71_RS04710	COG2860	membrane
BCB71_RS04740	COG0017	Asparaginyl-tRNA synthetase
BCB71_RS04765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCB71_RS04775	COG1538	Outer membrane efflux protein
BCB71_RS04785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCB71_RS04795	COG0513	Belongs to the DEAD box helicase family
BCB71_RS04800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCB71_RS04825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCB71_RS04830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCB71_RS04840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCB71_RS04850	COG2816	NAD+ diphosphatase activity
BCB71_RS04860	COG0481	GTPase activity
BCB71_RS04870	COG0470	DNA polymerase III
BCB71_RS04875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCB71_RS04880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCB71_RS04890	COG1640	4-alpha-glucanotransferase
BCB71_RS04905	COG0657	acetylesterase activity
BCB71_RS04905	COG2755	lipolytic protein G-D-S-L family
BCB71_RS04910	COG1530	ribonuclease E activity
BCB71_RS04915	COG0776	regulation of translation
BCB71_RS04930	COG0534	Mate efflux family protein
BCB71_RS04950	COG0297	glycogen (starch) synthase activity
BCB71_RS04960	COG2985	domain, Protein
BCB71_RS04960	COG0569	domain protein
BCB71_RS05010	COG1629	transport
BCB71_RS05010	COG4206	TonB-dependent receptor
BCB71_RS05035	COG0823	Involved in the tonB-independent uptake of proteins
BCB71_RS05035	COG1506	peptidase
BCB71_RS05050	COG2268	Band 7 protein
BCB71_RS05065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCB71_RS05070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCB71_RS05075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCB71_RS05110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCB71_RS05115	COG0321	lipoyl(octanoyl) transferase activity
BCB71_RS05145	COG0556	nucleotide-excision repair
BCB71_RS05170	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCB71_RS05190	COG3590	peptidase
BCB71_RS05200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCB71_RS05235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCB71_RS05285	COG4383	Mu-like prophage protein gp29
BCB71_RS05490	COG4974	Belongs to the 'phage' integrase family
BCB71_RS05495	COG0582	viral genome integration into host DNA
BCB71_RS05500	COG4221	oxidoreductase activity
BCB71_RS05510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCB71_RS05510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCB71_RS05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCB71_RS05520	COG0357	Ribosomal RNA small subunit methyltransferase G
BCB71_RS05545	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCB71_RS05570	COG1192	Involved in chromosome partitioning
BCB71_RS05575	COG1475	DNA binding
BCB71_RS05585	COG1388	LysM domain
BCB71_RS05585	COG3584	3D domain protein
BCB71_RS05595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCB71_RS05600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCB71_RS05600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCB71_RS05610	COG1002	Type II restriction enzyme, methylase subunits
BCB71_RS05630	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCB71_RS05640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCB71_RS05645	COG2873	o-acetylhomoserine
BCB71_RS05650	COG4452	Inner membrane protein CreD
BCB71_RS05655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCB71_RS05665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCB71_RS05670	COG2226	methyltransferase
BCB71_RS05675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCB71_RS05690	COG2252	PERMEase
BCB71_RS05715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCB71_RS05720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCB71_RS05725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCB71_RS05730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCB71_RS05730	COG1321	iron dependent repressor
BCB71_RS05755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCB71_RS05785	COG0515	serine threonine protein kinase
BCB71_RS05785	COG2815	serine threonine protein kinase
BCB71_RS05905	COG4383	Mu-like prophage protein gp29
BCB71_RS06020	COG0577	efflux transmembrane transporter activity
BCB71_RS06020	COG1136	(ABC) transporter
BCB71_RS06050	COG1368	sulfuric ester hydrolase activity
BCB71_RS06090	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BCB71_RS06130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCB71_RS06160	COG1505	serine-type exopeptidase activity
BCB71_RS06165	COG0006	proline dipeptidase activity
BCB71_RS06170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCB71_RS06180	COG0552	protein localization to endoplasmic reticulum
BCB71_RS06185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCB71_RS06190	COG0776	regulation of translation
BCB71_RS06200	COG0582	viral genome integration into host DNA
BCB71_RS06205	COG4974	Belongs to the 'phage' integrase family
BCB71_RS06225	COG2217	Heavy metal translocating P-type atpase
BCB71_RS06375	COG4974	Belongs to the 'phage' integrase family
BCB71_RS06380	COG0582	viral genome integration into host DNA
BCB71_RS06395	COG4953	penicillin-binding protein 1C
BCB71_RS06415	COG0038	chloride channel
BCB71_RS06420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCB71_RS06425	COG0009	L-threonylcarbamoyladenylate synthase
BCB71_RS06440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCB71_RS06455	COG0714	Associated with various cellular activities
BCB71_RS06470	COG2304	oxidoreductase activity
BCB71_RS06475	COG2304	oxidoreductase activity
BCB71_RS06500	COG0671	phosphoesterase, PA-phosphatase related
BCB71_RS06530	COG1183	phosphatidylcholine synthase activity
BCB71_RS06535	COG0688	phosphatidylethanolamine metabolic process
BCB71_RS06540	COG1074	ATP-dependent DNA helicase activity
BCB71_RS06555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCB71_RS06560	COG0612	Peptidase, M16
BCB71_RS06590	COG0300	oxidoreductase activity
BCB71_RS06600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCB71_RS06610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCB71_RS06615	COG1051	belongs to the nudix hydrolase family
BCB71_RS06620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCB71_RS06640	COG2264	protein methyltransferase activity
BCB71_RS06645	COG0484	heat shock protein binding
BCB71_RS06650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCB71_RS06660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCB71_RS06665	COG0784	Response regulator, receiver
BCB71_RS06665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCB71_RS06665	COG2198	Histidine kinase
BCB71_RS06665	COG2205	protein histidine kinase activity
BCB71_RS06690	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCB71_RS06705	COG0745	RESPONSE REGULATOR receiver
BCB71_RS06710	COG5002	protein histidine kinase activity
BCB71_RS06720	COG0793	Belongs to the peptidase S41A family
BCB71_RS06740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCB71_RS06745	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BCB71_RS06755	COG3033	Beta-eliminating lyase
BCB71_RS06765	COG0310	cobalt ion transport
BCB71_RS06770	COG1116	anion transmembrane transporter activity
BCB71_RS06775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCB71_RS06785	COG1151	hydroxylamine reductase activity
BCB71_RS06810	COG1193	negative regulation of DNA recombination
BCB71_RS06820	COG0574	Belongs to the PEP-utilizing enzyme family
BCB71_RS06820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCB71_RS06825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCB71_RS06840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BCB71_RS06845	COG2059	Chromate
BCB71_RS06860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCB71_RS06865	COG1252	NADH dehydrogenase
BCB71_RS06870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCB71_RS06875	COG1882	Formate acetyltransferase
BCB71_RS06900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCB71_RS06925	COG0745	RESPONSE REGULATOR receiver
BCB71_RS06930	COG5002	protein histidine kinase activity
BCB71_RS06935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCB71_RS06940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCB71_RS06945	COG3142	Participates in the control of copper homeostasis
BCB71_RS07000	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BCB71_RS07005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCB71_RS07015	COG0305	Participates in initiation and elongation during chromosome replication
BCB71_RS07020	COG0363	glucosamine-6-phosphate deaminase activity
BCB71_RS07025	COG0426	domain, Protein
BCB71_RS07030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCB71_RS07035	COG0673	inositol 2-dehydrogenase activity
BCB71_RS07050	COG1381	Involved in DNA repair and RecF pathway recombination
BCB71_RS07055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCB71_RS07080	COG0156	8-amino-7-oxononanoate synthase activity
BCB71_RS07095	COG3942	CHAP domain
BCB71_RS07095	COG1388	LysM domain
BCB71_RS07105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BCB71_RS07125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCB71_RS07180	COG4771	TonB-dependent receptor
BCB71_RS07190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCB71_RS07195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCB71_RS07210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCB71_RS07215	COG0110	maltose O-acetyltransferase activity
BCB71_RS07220	COG1757	Na H antiporter
BCB71_RS07250	COG0126	phosphoglycerate kinase activity
BCB71_RS07260	COG0534	Mate efflux family protein
BCB71_RS07275	COG0058	SHG alpha-glucan phosphorylase activity
BCB71_RS07330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCB71_RS07335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCB71_RS07340	COG0739	heme binding
BCB71_RS07360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCB71_RS07385	COG1120	ATPase activity
BCB71_RS07390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCB71_RS07390	COG1918	ferrous iron import across plasma membrane
BCB71_RS07405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BCB71_RS07405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCB71_RS07415	COG0489	protein tyrosine kinase activity
BCB71_RS07420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCB71_RS07465	COG2373	Large extracellular alpha-helical protein
BCB71_RS07500	COG0629	single-stranded DNA binding
BCB71_RS07555	COG2755	lipolytic protein G-D-S-L family
BCB71_RS07555	COG0657	acetylesterase activity
BCB71_RS07580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCB71_RS07585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BCB71_RS07590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCB71_RS07595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCB71_RS07600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCB71_RS07610	COG2003	Belongs to the UPF0758 family
BCB71_RS07615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCB71_RS07620	COG0101	tRNA pseudouridine synthase activity
BCB71_RS07625	COG1797	cobyrinic acid a,c-diamide synthase activity
BCB71_RS07670	COG4771	TonB-dependent receptor
BCB71_RS07725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCB71_RS07745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCB71_RS07770	COG0438	transferase activity, transferring glycosyl groups
BCB71_RS07775	COG3475	LICD family
BCB71_RS07785	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BCB71_RS07790	COG1805	sodium ion transport
BCB71_RS07795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BCB71_RS07805	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BCB71_RS07820	COG2885	chlorophyll binding
BCB71_RS07830	COG4974	Belongs to the 'phage' integrase family
BCB71_RS07835	COG4974	Belongs to the 'phage' integrase family
BCB71_RS07840	COG5549	protein import
BCB71_RS07840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCB71_RS07915	COG4974	Belongs to the 'phage' integrase family
BCB71_RS07920	COG4974	Belongs to the 'phage' integrase family
BCB71_RS07930	COG2715	membrane protein required for spore maturation
BCB71_RS07935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCB71_RS07970	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCB71_RS07985	COG0738	Major facilitator superfamily
BCB71_RS07990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCB71_RS08015	COG0577	efflux transmembrane transporter activity
BCB71_RS08015	COG1136	(ABC) transporter
BCB71_RS08020	COG1136	(ABC) transporter
BCB71_RS08030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCB71_RS08030	COG0519	Catalyzes the synthesis of GMP from XMP
BCB71_RS08035	COG2217	Heavy metal translocating P-type atpase
BCB71_RS08085	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BCB71_RS08105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCB71_RS08110	COG4771	TonB-dependent receptor
BCB71_RS08120	COG1480	7TM receptor with intracellular HD hydrolase
BCB71_RS08155	COG4974	Belongs to the 'phage' integrase family
BCB71_RS08160	COG4974	Belongs to the 'phage' integrase family
BCB71_RS08235	COG4974	Belongs to the 'phage' integrase family
BCB71_RS08240	COG0582	viral genome integration into host DNA
BCB71_RS08265	COG0742	ribosomal rna small subunit methyltransferase
BCB71_RS08275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCB71_RS08285	COG0427	acetyl-CoA hydrolase
BCB71_RS08310	COG0167	dihydroorotate dehydrogenase activity
BCB71_RS08330	COG0335	large ribosomal subunit rRNA binding
BCB71_RS08335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCB71_RS08340	COG0393	Putative heavy-metal-binding
BCB71_RS08345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCB71_RS08350	COG2166	iron-sulfur cluster assembly
BCB71_RS08355	COG2234	aminopeptidase activity
BCB71_RS08390	COG1139	Iron-sulfur cluster binding protein
BCB71_RS08400	COG1620	l-lactate permease
BCB71_RS08435	COG1522	sequence-specific DNA binding
BCB71_RS08455	COG0811	peptide transport
BCB71_RS08465	COG0084	hydrolase, TatD family'
BCB71_RS08485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BCB71_RS08495	COG0346	lactoylglutathione lyase activity
BCB71_RS08500	COG0259	pyridoxamine-phosphate oxidase activity
BCB71_RS08510	COG1629	transport
BCB71_RS08520	COG1137	ATPase activity
BCB71_RS08525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCB71_RS08530	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCB71_RS08530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCB71_RS08535	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCB71_RS08545	COG0659	secondary active sulfate transmembrane transporter activity
BCB71_RS08560	COG0297	glycogen (starch) synthase activity
BCB71_RS08565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCB71_RS08570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCB71_RS08575	COG0534	Mate efflux family protein
BCB71_RS08595	COG1418	mRNA catabolic process
BCB71_RS08600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCB71_RS08620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCB71_RS08620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCB71_RS08625	COG0514	ATP-dependent DNA helicase (RecQ)
BCB71_RS08635	COG1649	PFAM Uncharacterised BCR, COG1649
BCB71_RS08640	COG0492	ferredoxin-NADP+ reductase activity
BCB71_RS08645	COG2249	NAD(P)H dehydrogenase (quinone) activity
BCB71_RS08655	COG1674	ftsk spoiiie
BCB71_RS08670	COG2986	histidine ammonia-lyase
BCB71_RS08680	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BCB71_RS08690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCB71_RS08695	COG3339	Conserved Protein
BCB71_RS08700	COG0534	Mate efflux family protein
BCB71_RS08725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCB71_RS08735	COG3015	lipoprotein NlpE involved in copper resistance
BCB71_RS08740	COG0493	'glutamate synthase
BCB71_RS08745	COG0543	2 iron, 2 sulfur cluster binding
BCB71_RS08750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCB71_RS08755	COG0564	pseudouridine synthase activity
BCB71_RS08760	COG1253	flavin adenine dinucleotide binding
BCB71_RS08765	COG1760	l-serine dehydratase
BCB71_RS08810	COG0363	glucosamine-6-phosphate deaminase activity
BCB71_RS08815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCB71_RS08840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCB71_RS08845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCB71_RS08850	COG1185	polyribonucleotide nucleotidyltransferase activity
BCB71_RS08855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCB71_RS08855	COG0047	phosphoribosylformylglycinamidine synthase activity
BCB71_RS08860	COG1280	lysine exporter protein (LysE YggA)
BCB71_RS08870	COG0859	PFAM glycosyl transferase family 9
BCB71_RS08875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCB71_RS08880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCB71_RS08895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCB71_RS08935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCB71_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
BCB71_RS08945	COG0009	L-threonylcarbamoyladenylate synthase
BCB71_RS08965	COG4206	TonB-dependent receptor
BCB71_RS08980	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCB71_RS08990	COG0471	metal ion transport
BCB71_RS08995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCB71_RS09010	COG3344	reverse transcriptase
BCB71_RS09030	COG4974	Belongs to the 'phage' integrase family
BCB71_RS09065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCB71_RS09070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCB71_RS09095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCB71_RS09100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCB71_RS09120	COG0359	binds to the 23S rRNA
BCB71_RS09125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCB71_RS09130	COG0360	Binds together with S18 to 16S ribosomal RNA
BCB71_RS09145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCB71_RS09150	COG2177	Part of the ABC transporter FtsEX involved in
BCB71_RS09160	COG1968	undecaprenyl-diphosphatase activity
BCB71_RS09165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCB71_RS09170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCB71_RS09175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCB71_RS09190	COG3041	Addiction module toxin RelE StbE family
BCB71_RS09195	COG0632	four-way junction helicase activity
BCB71_RS09220	COG2885	chlorophyll binding
BCB71_RS09230	COG0612	Peptidase, M16
BCB71_RS09270	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BCB71_RS09275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCB71_RS09305	COG0531	amino acid
BCB71_RS09325	COG0463	Glycosyl transferase, family 2
BCB71_RS09345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCB71_RS09365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCB71_RS09370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCB71_RS09375	COG0037	tRNA processing
BCB71_RS09385	COG0779	Required for maturation of 30S ribosomal subunits
BCB71_RS09390	COG0195	Participates in both transcription termination and antitermination
BCB71_RS09390	COG2251	uridine kinase activity
BCB71_RS09395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCB71_RS09395	COG3266	domain, Protein
BCB71_RS09405	COG0719	Fe-S assembly protein
BCB71_RS09415	COG0396	ATPase activity
BCB71_RS09420	COG0719	Fe-S assembly protein
BCB71_RS09430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCB71_RS09435	COG3177	Filamentation induced by cAMP protein fic
BCB71_RS09445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCB71_RS09445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCB71_RS09450	COG0436	Aminotransferase
BCB71_RS09470	COG0018	arginyl-trna synthetase
BCB71_RS09490	COG0653	protein targeting
BCB71_RS09505	COG2095	MarC family integral membrane protein
BCB71_RS09520	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCB71_RS09530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCB71_RS09540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCB71_RS09560	COG1205	dead DEAH box helicase
BCB71_RS09560	COG1111	helicase
BCB71_RS09585	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCB71_RS09590	COG0740	serine-type endopeptidase activity
BCB71_RS09595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCB71_RS09600	COG0514	ATP-dependent DNA helicase (RecQ)
BCB71_RS09630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCB71_RS09635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCB71_RS09640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCB71_RS09645	COG3189	MarR family transcriptional regulator
BCB71_RS09680	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BCB71_RS09680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCB71_RS09685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCB71_RS09695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCB71_RS09700	COG0826	peptidase U32
BCB71_RS09705	COG0542	response to heat
BCB71_RS09710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCB71_RS09715	COG0488	(ABC) transporter
BCB71_RS09720	COG4206	TonB-dependent receptor
BCB71_RS09720	COG1629	transport
BCB71_RS09730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCB71_RS09745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCB71_RS09750	COG2855	membrane
BCB71_RS09755	COG2502	aspartate--ammonia ligase
BCB71_RS09760	COG0617	tRNA 3'-terminal CCA addition
BCB71_RS09770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCB71_RS09780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCB71_RS09780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCB71_RS09785	COG0427	acetyl-CoA hydrolase
BCB71_RS09790	COG2255	four-way junction helicase activity
BCB71_RS09810	COG3591	Belongs to the peptidase S1B family
BCB71_RS09815	COG0463	Glycosyl transferase, family 2
BCB71_RS09815	COG1216	Glycosyl transferase, family 2
BCB71_RS09855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCB71_RS09880	COG4974	Belongs to the 'phage' integrase family
BCB71_RS09885	COG4974	Belongs to the 'phage' integrase family
BCB71_RS09890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCB71_RS09900	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BCB71_RS09905	COG3005	denitrification pathway
BCB71_RS09925	COG1335	isochorismatase
BCB71_RS09955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCB71_RS09965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCB71_RS09990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCB71_RS09995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCB71_RS10000	COG1748	Saccharopine dehydrogenase
BCB71_RS10010	COG1011	Hydrolase
BCB71_RS10020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCB71_RS10025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCB71_RS10030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCB71_RS10070	COG1595	DNA-templated transcription, initiation
BCB71_RS10080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCB71_RS10095	COG4191	Histidine kinase
BCB71_RS10115	COG1131	(ABC) transporter
BCB71_RS10120	COG1131	(ABC) transporter
BCB71_RS10130	COG0842	Transport permease protein
BCB71_RS10155	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BCB71_RS10160	COG1492	cobalamin metabolic process
BCB71_RS10165	COG0539	negative regulation of cytoplasmic translation
BCB71_RS10175	COG0488	(ABC) transporter
BCB71_RS10185	COG0436	Aminotransferase
BCB71_RS10190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCB71_RS10195	COG0287	Prephenate dehydrogenase
BCB71_RS10215	COG0726	polysaccharide deacetylase
BCB71_RS10225	COG1053	succinate dehydrogenase
BCB71_RS10235	COG0758	DNA mediated transformation
BCB71_RS10235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCB71_RS10255	COG1215	transferase activity, transferring glycosyl groups
BCB71_RS10260	COG2211	Major facilitator Superfamily
BCB71_RS10265	COG3876	Protein conserved in bacteria
BCB71_RS10275	COG0527	aspartate kinase activity
BCB71_RS10275	COG0460	homoserine dehydrogenase
BCB71_RS10300	COG0514	ATP-dependent DNA helicase (RecQ)
BCB71_RS10320	COG0124	histidyl-tRNA synthetase
BCB71_RS10325	COG2738	Putative neutral zinc metallopeptidase
BCB71_RS10330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCB71_RS10335	COG0735	belongs to the Fur family
BCB71_RS10345	COG1940	carbohydrate kinase activity
BCB71_RS10360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCB71_RS10365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCB71_RS10385	COG0280	phosphate acetyltransferase
BCB71_RS10390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCB71_RS10395	COG0336	Belongs to the RNA methyltransferase TrmD family
BCB71_RS10400	COG1127	ABC transporter
BCB71_RS10405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCB71_RS10420	COG2321	neutral zinc metallopeptidase
BCB71_RS10425	COG0012	GTP binding
BCB71_RS10435	COG0793	Belongs to the peptidase S41A family
BCB71_RS10435	COG4946	Tricorn protease homolog
BCB71_RS10445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCB71_RS10455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCB71_RS10480	COG0516	GMP reductase activity
BCB71_RS10495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCB71_RS10500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCB71_RS10510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCB71_RS10540	COG1570	exodeoxyribonuclease VII activity
BCB71_RS10550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCB71_RS10560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BCB71_RS10565	COG0706	membrane insertase activity
BCB71_RS10570	COG0504	CTP synthase activity
BCB71_RS10575	COG2333	competence protein COMEC
BCB71_RS10575	COG0658	competence protein
BCB71_RS10585	COG2226	methyltransferase
BCB71_RS10595	COG1442	glycosyl transferase family 8
BCB71_RS10615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCB71_RS10685	COG3759	membrane
BCB71_RS10695	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCB71_RS10700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCB71_RS10705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCB71_RS10720	COG0237	dephospho-CoA kinase activity
BCB71_RS10730	COG1862	Preprotein translocase
BCB71_RS10735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCB71_RS10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCB71_RS10745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCB71_RS10750	COG2205	protein histidine kinase activity
BCB71_RS10855	COG0142	geranyltranstransferase activity
BCB71_RS10860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCB71_RS10860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCB71_RS10880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCB71_RS10890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCB71_RS10910	COG0295	cytidine deaminase activity
BCB71_RS10920	COG1595	DNA-templated transcription, initiation
BCB71_RS10935	COG1694	Mazg nucleotide pyrophosphohydrolase
BCB71_RS10940	COG1490	D-aminoacyl-tRNA deacylase activity
BCB71_RS10945	COG0322	excinuclease ABC activity
BCB71_RS10950	COG0445	tRNA wobble uridine modification
BCB71_RS10965	COG0628	permease
BCB71_RS10970	COG0346	lactoylglutathione lyase activity
BCB71_RS10975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCB71_RS10990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BCB71_RS10995	COG0205	6-phosphofructokinase activity
BCB71_RS11020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCB71_RS11025	COG3386	PFAM SMP-30 Gluconolaconase
BCB71_RS11030	COG0557	exoribonuclease II activity
BCB71_RS11055	COG4771	TonB-dependent receptor
BCB71_RS11075	COG1785	Belongs to the alkaline phosphatase family
BCB71_RS11085	COG0006	proline dipeptidase activity
BCB71_RS11100	COG2957	Belongs to the agmatine deiminase family
BCB71_RS11105	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCB71_RS11115	COG1668	transmembrane transport
BCB71_RS11125	COG4152	abc transporter atp-binding protein
BCB71_RS11135	COG0305	Participates in initiation and elongation during chromosome replication
BCB71_RS11135	COG0358	DNA primase activity
BCB71_RS11145	COG1162	GTPase activity
BCB71_RS11150	COG0233	cytoplasmic translational termination
BCB71_RS11155	COG0528	UMP kinase activity
BCB71_RS11160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCB71_RS11165	COG0495	leucyl-tRNA aminoacylation
BCB71_RS11170	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BCB71_RS11205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCB71_RS11210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCB71_RS11215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCB71_RS11235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCB71_RS11245	COG0275	rRNA processing
BCB71_RS11260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCB71_RS11265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCB71_RS11270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCB71_RS11275	COG0772	Belongs to the SEDS family
BCB71_RS11280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCB71_RS11285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCB71_RS11295	COG0849	cell division
BCB71_RS11300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCB71_RS11325	COG3118	belongs to the thioredoxin family
BCB71_RS11335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCB71_RS11340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCB71_RS11345	COG0052	Belongs to the universal ribosomal protein uS2 family
BCB71_RS11350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCB71_RS11360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCB71_RS11365	COG1136	(ABC) transporter
BCB71_RS11380	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BCB71_RS11385	COG0571	ribonuclease III activity
BCB71_RS11390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCB71_RS11395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCB71_RS11450	COG0151	Belongs to the GarS family
BCB71_RS11460	COG1238	metal cluster binding
BCB71_RS11465	COG0612	Peptidase, M16
BCB71_RS11475	COG0598	Magnesium transport protein CorA
BCB71_RS11480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCB71_RS11500	COG4771	TonB-dependent receptor
BCB71_RS11510	COG1703	isobutyryl-CoA mutase activity
BCB71_RS11535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCB71_RS11540	COG0793	Belongs to the peptidase S41A family
BCB71_RS11545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCB71_RS11550	COG0482	sulfurtransferase activity
BCB71_RS11555	COG1217	gtp-binding protein TYPA
BCB71_RS11560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCB71_RS11570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCB71_RS11580	COG0423	glycine-tRNA ligase activity
BCB71_RS11600	COG1696	Membrane protein involved in D-alanine export
BCB71_RS11605	COG0792	nuclease activity
BCB71_RS11630	COG0205	6-phosphofructokinase activity
BCB71_RS11635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCB71_RS11645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCB71_RS11660	COG1477	protein flavinylation
BCB71_RS11665	COG0778	Nitroreductase
BCB71_RS11720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCB71_RS11720	COG0758	DNA mediated transformation
BCB71_RS11725	COG2194	sulfuric ester hydrolase activity
BCB71_RS11730	COG0501	Belongs to the peptidase M48B family
BCB71_RS11740	COG0826	peptidase U32
BCB71_RS11750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCB71_RS11755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCB71_RS11760	COG0509	glycine decarboxylation via glycine cleavage system
BCB71_RS11770	COG1234	tRNA 3'-trailer cleavage
BCB71_RS11800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BCB71_RS11815	COG2884	Cell division ATP-binding protein ftsE
BCB71_RS11820	COG0527	aspartate kinase activity
BCB71_RS11830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCB71_RS11835	COG0049	tRNA binding
BCB71_RS11840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCB71_RS11845	COG0051	transcription antitermination factor activity, RNA binding
BCB71_RS11850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCB71_RS11855	COG0088	Forms part of the polypeptide exit tunnel
BCB71_RS11860	COG0089	rRNA binding
BCB71_RS11865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCB71_RS11870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCB71_RS11875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCB71_RS11880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCB71_RS11885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCB71_RS11890	COG0255	Belongs to the universal ribosomal protein uL29 family
BCB71_RS11895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCB71_RS11900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCB71_RS11905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCB71_RS11910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCB71_RS11915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCB71_RS11920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCB71_RS11925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCB71_RS11930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCB71_RS11935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCB71_RS11940	COG1841	ribosomal large subunit assembly
BCB71_RS11945	COG0200	Binds to the 23S rRNA
BCB71_RS11950	COG0201	protein transport
BCB71_RS11955	COG0024	Methionine aminopeptidase
BCB71_RS11960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCB71_RS11965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCB71_RS11970	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCB71_RS11975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCB71_RS11980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCB71_RS11985	COG0202	RNA polymerase activity
BCB71_RS11990	COG0203	ribosomal protein L17
BCB71_RS12050	COG2211	Major facilitator Superfamily
BCB71_RS12090	COG3344	reverse transcriptase
BCB71_RS12160	COG4974	Belongs to the 'phage' integrase family
BCB71_RS12165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCB71_RS12220	COG3344	reverse transcriptase
BCB71_RS12275	COG3344	reverse transcriptase
BCB71_RS12285	COG4974	Belongs to the 'phage' integrase family
BCB71_RS12290	COG4974	Belongs to the 'phage' integrase family
BCB71_RS12410	COG4974	Belongs to the 'phage' integrase family
BCB71_RS12435	COG0159	tryptophan synthase activity
BCB71_RS12440	COG0135	phosphoribosylanthranilate isomerase activity
BCB71_RS12445	COG0134	indole-3-glycerol-phosphate synthase activity
BCB71_RS12450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCB71_RS12455	COG0512	Glutamine amidotransferase of anthranilate synthase
BCB71_RS12460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCB71_RS12465	COG0133	tryptophan synthase activity
BCB71_RS12480	COG0594	ribonuclease P activity
BCB71_RS12485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCB71_RS12490	COG0084	hydrolase, TatD family'
BCB71_RS12500	COG0463	Glycosyl transferase, family 2
BCB71_RS12510	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCB71_RS12810	COG1621	beta-fructofuranosidase activity
BCB71_RS12860	COG1187	pseudouridine synthase activity
BCB71_RS12935	COG0343	queuine tRNA-ribosyltransferase activity
BCB71_RS12990	COG1216	Glycosyl transferase, family 2
BCB71_RS13135	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCB71_RS13240	COG1705	Flagellar rod assembly protein muramidase FlgJ
BCB71_RS13240	COG3951	Flagellar rod assembly protein muramidase FlgJ
BCB71_RS13245	COG5549	protein import
BCB71_RS13245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCB71_RS13250	COG5549	protein import
BCB71_RS13250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCB71_RS13260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCB71_RS13265	COG5549	protein import
BCB71_RS13265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain