locus-tag	class	description
LPB73_RS00070	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS00080	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS00090	COG0515	serine threonine protein kinase
LPB73_RS00090	COG2815	serine threonine protein kinase
LPB73_RS00095	COG2116	formate transmembrane transporter activity
LPB73_RS00100	COG2146	nitrite reductase [NAD(P)H] activity
LPB73_RS00105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB73_RS00120	COG2309	aminopeptidase activity
LPB73_RS00125	COG4977	sequence-specific DNA binding
LPB73_RS00135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPB73_RS00140	COG2218	PFAM glutamate synthase alpha subunit domain protein
LPB73_RS00145	COG0069	glutamate synthase activity
LPB73_RS00150	COG0174	glutamine synthetase
LPB73_RS00170	COG2271	Major facilitator Superfamily
LPB73_RS00175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LPB73_RS00180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPB73_RS00190	COG1121	(ABC) transporter
LPB73_RS00200	COG0803	Belongs to the bacterial solute-binding protein 9 family
LPB73_RS00205	COG0523	cobalamin synthesis protein
LPB73_RS00225	COG4689	acetoacetate decarboxylase
LPB73_RS00235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LPB73_RS00240	COG0251	oxidation-reduction process
LPB73_RS00275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LPB73_RS00280	COG0330	HflC and HflK could
LPB73_RS00315	COG5001	Diguanylate cyclase
LPB73_RS00315	COG4251	negative regulation of phosphorylation
LPB73_RS00315	COG3706	GGDEF domain
LPB73_RS00315	COG2203	Gaf domain
LPB73_RS00320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LPB73_RS00325	COG2951	lytic endotransglycosylase activity
LPB73_RS00340	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS00345	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS00350	COG3237	CsbD-like
LPB73_RS00385	COG0067	glutamate synthase
LPB73_RS00385	COG0069	glutamate synthase activity
LPB73_RS00385	COG0070	glutamate synthase
LPB73_RS00395	COG0071	Belongs to the small heat shock protein (HSP20) family
LPB73_RS00405	COG1280	lysine exporter protein (LysE YggA)
LPB73_RS00415	COG0583	DNA-binding transcription factor activity
LPB73_RS00420	COG0483	inositol monophosphate 1-phosphatase activity
LPB73_RS00445	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LPB73_RS00460	COG0765	amino acid transport
LPB73_RS00465	COG0765	amino acid transport
LPB73_RS00470	COG1126	abc transporter atp-binding protein
LPB73_RS00480	COG0840	transmembrane signaling receptor activity
LPB73_RS00495	COG0840	transmembrane signaling receptor activity
LPB73_RS00500	COG0840	transmembrane signaling receptor activity
LPB73_RS00505	COG2192	nodulation
LPB73_RS00515	COG1902	pentaerythritol trinitrate reductase activity
LPB73_RS00530	COG0181	hydroxymethylbilane synthase activity
LPB73_RS00545	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS00550	COG2900	Belongs to the SlyX family
LPB73_RS00555	COG1054	Belongs to the UPF0176 family
LPB73_RS00560	COG3237	CsbD-like
LPB73_RS00570	COG0154	amidase activity
LPB73_RS00580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS00585	COG1116	anion transmembrane transporter activity
LPB73_RS00590	COG0028	Belongs to the TPP enzyme family
LPB73_RS00595	COG2072	flavoprotein involved in K transport
LPB73_RS00610	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LPB73_RS00615	COG0519	Catalyzes the synthesis of GMP from XMP
LPB73_RS00620	COG0354	folic acid binding
LPB73_RS00625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS00635	COG2733	membrane
LPB73_RS00640	COG0596	Alpha beta hydrolase
LPB73_RS00650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS00665	COG2186	Transcriptional regulator
LPB73_RS00675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPB73_RS00710	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS00715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LPB73_RS00725	COG0668	transmembrane transport
LPB73_RS00745	COG1764	response to oxidative stress
LPB73_RS00750	COG0469	pyruvate kinase activity
LPB73_RS00765	COG3750	Belongs to the UPF0335 family
LPB73_RS00770	COG3108	Peptidase M15
LPB73_RS00775	COG2989	Protein conserved in bacteria
LPB73_RS00780	COG2204	response regulator
LPB73_RS00785	COG0861	Integral membrane protein TerC family
LPB73_RS00845	COG0387	Pfam Sodium calcium exchanger
LPB73_RS00865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LPB73_RS00870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LPB73_RS00875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LPB73_RS00910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS00915	COG5001	Diguanylate cyclase
LPB73_RS00915	COG3300	MHYT domain
LPB73_RS00920	COG3842	ATPase activity
LPB73_RS00925	COG1176	ABC-type spermidine putrescine transport system, permease component I
LPB73_RS00930	COG1177	transmembrane transport
LPB73_RS00960	COG1840	ABC-type Fe3 transport system, periplasmic component
LPB73_RS00965	COG4774	siderophore transport
LPB73_RS00975	COG0642	Histidine kinase
LPB73_RS00995	COG2205	protein histidine kinase activity
LPB73_RS01075	COG1192	Involved in chromosome partitioning
LPB73_RS01080	COG3300	MHYT domain
LPB73_RS01080	COG5001	Diguanylate cyclase
LPB73_RS01085	COG1937	Protein conserved in bacteria
LPB73_RS01095	COG0583	DNA-binding transcription factor activity
LPB73_RS01100	COG0492	ferredoxin-NADP+ reductase activity
LPB73_RS01105	COG1522	sequence-specific DNA binding
LPB73_RS01115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LPB73_RS01120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LPB73_RS01125	COG2814	Major facilitator Superfamily
LPB73_RS01145	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS01150	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS01155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS01210	COG0583	DNA-binding transcription factor activity
LPB73_RS01240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB73_RS01265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS01265	COG1116	anion transmembrane transporter activity
LPB73_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS01285	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LPB73_RS01295	COG1129	ABC transporter
LPB73_RS01305	COG0683	leucine binding
LPB73_RS01325	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LPB73_RS01335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LPB73_RS01340	COG0408	coproporphyrinogen oxidase activity
LPB73_RS01345	COG5398	heme oxygenase
LPB73_RS01355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LPB73_RS01370	COG0400	carboxylic ester hydrolase activity
LPB73_RS01375	COG0346	lactoylglutathione lyase activity
LPB73_RS01380	COG0583	DNA-binding transcription factor activity
LPB73_RS01385	COG0210	DNA helicase
LPB73_RS01395	COG0784	Response regulator, receiver
LPB73_RS01395	COG2205	protein histidine kinase activity
LPB73_RS01425	COG0010	Belongs to the arginase family
LPB73_RS01435	COG0366	Alpha amylase catalytic
LPB73_RS01440	COG0747	negative chemotaxis
LPB73_RS01445	COG4166	transmembrane transport
LPB73_RS01450	COG0601	transmembrane transport
LPB73_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS01460	COG4608	Belongs to the ABC transporter superfamily
LPB73_RS01470	COG0154	amidase activity
LPB73_RS01475	COG0444	Belongs to the ABC transporter superfamily
LPB73_RS01480	COG1546	Belongs to the CinA family
LPB73_RS01480	COG1058	Belongs to the CinA family
LPB73_RS01490	COG0583	DNA-binding transcription factor activity
LPB73_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS01510	COG0583	DNA-binding transcription factor activity
LPB73_RS01515	COG1024	Enoyl-CoA hydratase
LPB73_RS01525	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS01530	COG2267	carboxylic ester hydrolase activity
LPB73_RS01535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPB73_RS01540	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LPB73_RS01550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LPB73_RS01560	COG1722	exodeoxyribonuclease VII activity
LPB73_RS01565	COG0123	including yeast histone deacetylase and acetoin utilization protein
LPB73_RS01570	COG5001	Diguanylate cyclase
LPB73_RS01570	COG5002	protein histidine kinase activity
LPB73_RS01580	COG1024	Enoyl-CoA hydratase
LPB73_RS01585	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS01610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LPB73_RS01630	COG1131	(ABC) transporter
LPB73_RS01715	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LPB73_RS01720	COG3791	Glutathione-dependent formaldehyde-activating
LPB73_RS01745	COG0251	oxidation-reduction process
LPB73_RS01775	COG4177	L-phenylalanine transmembrane transporter activity
LPB73_RS01780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LPB73_RS01800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPB73_RS01805	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LPB73_RS01820	COG1127	ABC transporter
LPB73_RS01825	COG3218	ABC-type transport auxiliary lipoprotein component
LPB73_RS01825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LPB73_RS01835	COG0747	negative chemotaxis
LPB73_RS01850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB73_RS01860	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS01870	COG0183	Belongs to the thiolase family
LPB73_RS01875	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LPB73_RS01895	COG1850	ribulose-bisphosphate carboxylase activity
LPB73_RS01900	COG4451	ribulose bisphosphate carboxylase, small
LPB73_RS01910	COG4191	Histidine kinase
LPB73_RS01910	COG0784	Response regulator, receiver
LPB73_RS01960	COG1278	Cold shock
LPB73_RS01990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPB73_RS02000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS02005	COG0765	amino acid transport
LPB73_RS02010	COG0765	amino acid transport
LPB73_RS02060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LPB73_RS02065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPB73_RS02100	COG1794	racemase activity, acting on amino acids and derivatives
LPB73_RS02130	COG0601	transmembrane transport
LPB73_RS02135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS02140	COG0444	Belongs to the ABC transporter superfamily
LPB73_RS02145	COG4608	Belongs to the ABC transporter superfamily
LPB73_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS02155	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02160	COG1522	sequence-specific DNA binding
LPB73_RS02175	COG0492	ferredoxin-NADP+ reductase activity
LPB73_RS02195	COG1309	transcriptional regulator
LPB73_RS02210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPB73_RS02220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LPB73_RS02225	COG5328	Belongs to the UPF0262 family
LPB73_RS02230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPB73_RS02235	COG0424	maF-like protein
LPB73_RS02240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LPB73_RS02250	COG0582	viral genome integration into host DNA
LPB73_RS02315	COG0583	DNA-binding transcription factor activity
LPB73_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02340	COG2267	carboxylic ester hydrolase activity
LPB73_RS02345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS02365	COG2207	Transcriptional regulator
LPB73_RS02380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LPB73_RS02410	COG4191	Histidine kinase
LPB73_RS02415	COG4566	intracellular signal transduction
LPB73_RS02435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LPB73_RS02450	COG5002	protein histidine kinase activity
LPB73_RS02460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB73_RS02475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB73_RS02480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS02515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPB73_RS02520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB73_RS02525	COG0071	Belongs to the small heat shock protein (HSP20) family
LPB73_RS02535	COG5001	Diguanylate cyclase
LPB73_RS02535	COG3300	MHYT domain
LPB73_RS02555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS02565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS02585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS02590	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02610	COG3321	synthase
LPB73_RS02610	COG0604	alcohol dehydrogenase
LPB73_RS02615	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LPB73_RS02620	COG3246	L-lysine catabolic process to acetate
LPB73_RS02625	COG0167	dihydroorotate dehydrogenase activity
LPB73_RS02675	COG2249	NAD(P)H dehydrogenase (quinone) activity
LPB73_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS02770	COG3920	Histidine kinase
LPB73_RS02820	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LPB73_RS02830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB73_RS02835	COG0071	Belongs to the small heat shock protein (HSP20) family
LPB73_RS02845	COG0776	regulation of translation
LPB73_RS02885	COG0628	permease
LPB73_RS02960	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LPB73_RS02965	COG2943	transferase activity, transferring hexosyl groups
LPB73_RS03065	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS03085	COG1335	isochorismatase
LPB73_RS03095	COG2080	2 iron, 2 sulfur cluster binding
LPB73_RS03100	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LPB73_RS03105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LPB73_RS03120	COG4191	Histidine kinase
LPB73_RS03120	COG0784	Response regulator, receiver
LPB73_RS03190	COG0784	Response regulator, receiver
LPB73_RS03190	COG4191	Histidine kinase
LPB73_RS03290	COG1595	DNA-templated transcription, initiation
LPB73_RS03295	COG3806	Anti-sigma factor
LPB73_RS03305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LPB73_RS03390	COG3327	negative regulation of DNA-templated transcription, initiation
LPB73_RS03395	COG3396	Phenylacetate-CoA oxygenase
LPB73_RS03400	COG3460	Phenylacetate-CoA oxygenase
LPB73_RS03405	COG3396	Phenylacetate-CoA oxygenase
LPB73_RS03410	COG2151	metal-sulfur cluster biosynthetic enzyme
LPB73_RS03415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPB73_RS03435	COG2030	dehydratase
LPB73_RS03435	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS03450	COG2050	protein possibly involved in aromatic compounds catabolism
LPB73_RS03455	COG1024	Enoyl-CoA hydratase
LPB73_RS03465	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS03505	COG1129	ABC transporter
LPB73_RS03510	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS03515	COG3246	L-lysine catabolic process to acetate
LPB73_RS03525	COG1609	Transcriptional regulator
LPB73_RS03530	COG3485	protocatechuate 3,4-dioxygenase
LPB73_RS03560	COG1879	ABC-type sugar transport system periplasmic component
LPB73_RS03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS03575	COG1129	ABC transporter
LPB73_RS03600	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS03605	COG2084	Dehydrogenase
LPB73_RS03610	COG3485	protocatechuate 3,4-dioxygenase
LPB73_RS03615	COG0277	FAD linked oxidase domain protein
LPB73_RS03620	COG1129	ABC transporter
LPB73_RS03625	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS03630	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS03650	COG1396	sequence-specific DNA binding
LPB73_RS03650	COG3800	Transcriptional regulator
LPB73_RS03660	COG2080	2 iron, 2 sulfur cluster binding
LPB73_RS03675	COG0446	pyridine nucleotide-disulphide oxidoreductase
LPB73_RS03695	COG3258	Cytochrome c
LPB73_RS03705	COG0505	Belongs to the CarA family
LPB73_RS03720	COG2852	Protein conserved in bacteria
LPB73_RS03725	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS03735	COG1388	LysM domain
LPB73_RS03735	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS03745	COG0598	Magnesium transport protein CorA
LPB73_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS03755	COG0259	pyridoxamine-phosphate oxidase activity
LPB73_RS03780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LPB73_RS03785	COG0406	alpha-ribazole phosphatase activity
LPB73_RS03805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LPB73_RS03820	COG1797	cobyrinic acid a,c-diamide synthase activity
LPB73_RS03850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LPB73_RS03860	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS03865	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS03875	COG1024	Enoyl-CoA hydratase
LPB73_RS03965	COG1024	Enoyl-CoA hydratase
LPB73_RS03970	COG3321	synthase
LPB73_RS03970	COG0300	oxidoreductase activity
LPB73_RS03970	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS03970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LPB73_RS04050	COG0784	Response regulator, receiver
LPB73_RS04060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS04065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS04075	COG0583	DNA-binding transcription factor activity
LPB73_RS04110	COG0628	permease
LPB73_RS04115	COG1388	LysM domain
LPB73_RS04115	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS04125	COG0840	transmembrane signaling receptor activity
LPB73_RS04130	COG0840	transmembrane signaling receptor activity
LPB73_RS04140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LPB73_RS04145	COG4208	sulfate ABC transporter
LPB73_RS04160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LPB73_RS04160	COG1648	precorrin-2 dehydrogenase activity
LPB73_RS04170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB73_RS04185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LPB73_RS04190	COG4208	sulfate ABC transporter
LPB73_RS04195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LPB73_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS04225	COG1678	Uncharacterized ACR, COG1678
LPB73_RS04230	COG5001	Diguanylate cyclase
LPB73_RS04235	COG0604	alcohol dehydrogenase
LPB73_RS04250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LPB73_RS04250	COG2755	lipolytic protein G-D-S-L family
LPB73_RS04265	COG0254	rRNA binding
LPB73_RS04270	COG1132	(ABC) transporter
LPB73_RS04275	COG0456	acetyltransferase
LPB73_RS04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS04305	COG0483	inositol monophosphate 1-phosphatase activity
LPB73_RS04315	COG0352	thiamine-phosphate diphosphorylase activity
LPB73_RS04320	COG3588	fructose-bisphosphate aldolase
LPB73_RS04335	COG0126	phosphoglycerate kinase activity
LPB73_RS04370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPB73_RS04375	COG1692	metallophosphoesterase
LPB73_RS04405	COG0840	transmembrane signaling receptor activity
LPB73_RS04420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LPB73_RS04425	COG0632	four-way junction helicase activity
LPB73_RS04435	COG2255	four-way junction helicase activity
LPB73_RS04445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB73_RS04450	COG1615	UPF0182 protein
LPB73_RS04455	COG0824	Thioesterase
LPB73_RS04465	COG2188	Transcriptional regulator
LPB73_RS04470	COG3624	Phosphonate C-P lyase system protein PhnG
LPB73_RS04475	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LPB73_RS04480	COG3626	phosphonate metabolism
LPB73_RS04485	COG3627	carbon phosphorus lyase activity
LPB73_RS04490	COG4107	phosphonate C-P lyase system protein PhnK
LPB73_RS04495	COG4778	phosphonate C-P lyase system protein PhnL
LPB73_RS04500	COG3454	Phosphonate metabolism
LPB73_RS04505	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LPB73_RS04540	COG4638	Rieske (2fe-2S)
LPB73_RS04550	COG0683	leucine binding
LPB73_RS04645	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS04685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS04690	COG2072	flavoprotein involved in K transport
LPB73_RS04695	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS04705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LPB73_RS04710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPB73_RS04715	COG4558	Periplasmic binding protein
LPB73_RS04725	COG4771	TonB-dependent receptor
LPB73_RS04775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LPB73_RS04775	COG2066	Belongs to the glutaminase family
LPB73_RS04780	COG0297	glycogen (starch) synthase activity
LPB73_RS04785	COG2814	Major facilitator Superfamily
LPB73_RS04810	COG1704	LemA family
LPB73_RS04825	COG0625	glutathione transferase activity
LPB73_RS04845	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LPB73_RS04870	COG1278	Cold shock
LPB73_RS04890	COG3768	UPF0283 membrane protein
LPB73_RS04895	COG3106	COG3106 Predicted ATPase
LPB73_RS04900	COG1272	protein, Hemolysin III
LPB73_RS04920	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LPB73_RS04930	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS04945	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS04950	COG4221	oxidoreductase activity
LPB73_RS04960	COG3300	MHYT domain
LPB73_RS04960	COG5001	Diguanylate cyclase
LPB73_RS04970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LPB73_RS04975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LPB73_RS05005	COG1492	cobalamin metabolic process
LPB73_RS05025	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LPB73_RS05030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LPB73_RS05045	COG2873	o-acetylhomoserine
LPB73_RS05080	COG2233	PERMEase
LPB73_RS05090	COG2080	2 iron, 2 sulfur cluster binding
LPB73_RS05090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LPB73_RS05120	COG4603	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS05125	COG3845	ABC transporter
LPB73_RS05145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB73_RS05160	COG1301	dicarboxylic acid transport
LPB73_RS05165	COG1396	sequence-specific DNA binding
LPB73_RS05175	COG3485	protocatechuate 3,4-dioxygenase
LPB73_RS05185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS05190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS05195	COG1116	anion transmembrane transporter activity
LPB73_RS05210	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB73_RS05215	COG0243	molybdopterin cofactor binding
LPB73_RS05220	COG3833	ABC-type maltose transport systems, permease component
LPB73_RS05225	COG1175	transmembrane transport
LPB73_RS05230	COG1653	transport
LPB73_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS05255	COG1053	succinate dehydrogenase
LPB73_RS05265	COG0745	RESPONSE REGULATOR receiver
LPB73_RS05270	COG0784	Response regulator, receiver
LPB73_RS05270	COG2198	Histidine kinase
LPB73_RS05270	COG5002	protein histidine kinase activity
LPB73_RS05290	COG1129	ABC transporter
LPB73_RS05310	COG0656	L-ascorbic acid biosynthetic process
LPB73_RS05315	COG0697	spore germination
LPB73_RS05320	COG5001	Diguanylate cyclase
LPB73_RS05320	COG3300	MHYT domain
LPB73_RS05325	COG1522	sequence-specific DNA binding
LPB73_RS05330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LPB73_RS05340	COG0351	phosphomethylpyrimidine kinase
LPB73_RS05400	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS05415	COG2814	Major facilitator Superfamily
LPB73_RS05420	COG4948	Mandelate Racemase Muconate Lactonizing
LPB73_RS05425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LPB73_RS05430	COG1127	ABC transporter
LPB73_RS05435	COG3218	ABC-type transport auxiliary lipoprotein component
LPB73_RS05435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LPB73_RS05460	COG0633	Ferredoxin
LPB73_RS05470	COG0492	ferredoxin-NADP+ reductase activity
LPB73_RS05490	COG0583	DNA-binding transcription factor activity
LPB73_RS05495	COG0477	Major facilitator Superfamily
LPB73_RS05510	COG3685	Protein conserved in bacteria
LPB73_RS05535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS05535	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LPB73_RS05540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB73_RS05545	COG1749	Flagellar hook protein flgE
LPB73_RS05550	COG1256	bacterial-type flagellum assembly
LPB73_RS05600	COG1706	bacterial-type flagellum-dependent cell motility
LPB73_RS05635	COG4786	Flagellar basal body rod
LPB73_RS05640	COG4786	Flagellar basal body rod
LPB73_RS05670	COG1338	Plays a role in the flagellum-specific transport system
LPB73_RS05680	COG1815	bacterial-type flagellum-dependent cell motility
LPB73_RS05685	COG1558	bacterial-type flagellum-dependent cell motility
LPB73_RS05690	COG1677	Flagellar hook-basal body complex protein FliE
LPB73_RS05695	COG1987	bacterial-type flagellum assembly
LPB73_RS05700	COG1684	flagellar biosynthetic protein fliR
LPB73_RS05705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPB73_RS05745	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LPB73_RS05745	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LPB73_RS05765	COG2917	probably involved in intracellular septation
LPB73_RS05780	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
LPB73_RS05795	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS05800	COG1802	Transcriptional regulator
LPB73_RS05920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPB73_RS05925	COG4608	Belongs to the ABC transporter superfamily
LPB73_RS05930	COG0444	Belongs to the ABC transporter superfamily
LPB73_RS05935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS05945	COG0747	negative chemotaxis
LPB73_RS05950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS05965	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LPB73_RS05965	COG2124	cytochrome p450
LPB73_RS05970	COG2267	carboxylic ester hydrolase activity
LPB73_RS06015	COG1024	Enoyl-CoA hydratase
LPB73_RS06040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LPB73_RS06045	COG3386	PFAM SMP-30 Gluconolaconase
LPB73_RS06055	COG0477	Major facilitator Superfamily
LPB73_RS06060	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS06095	COG3145	DNA-N1-methyladenine dioxygenase activity
LPB73_RS06110	COG0028	Belongs to the TPP enzyme family
LPB73_RS06115	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS06135	COG3971	2-oxopent-4-enoate hydratase activity
LPB73_RS06140	COG1846	Transcriptional regulator
LPB73_RS06150	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS06165	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LPB73_RS06180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS06205	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS06210	COG2721	sulfolactate sulfo-lyase activity
LPB73_RS06230	COG2081	HI0933 family
LPB73_RS06235	COG4303	Ethanolamine ammonia lyase large subunit
LPB73_RS06265	COG1562	ergosterol biosynthetic process
LPB73_RS06270	COG1562	ergosterol biosynthetic process
LPB73_RS06275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LPB73_RS06280	COG1657	PFAM Prenyltransferase squalene oxidase
LPB73_RS06285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPB73_RS06295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LPB73_RS06320	COG1595	DNA-templated transcription, initiation
LPB73_RS06340	COG1473	amidohydrolase
LPB73_RS06345	COG3685	Protein conserved in bacteria
LPB73_RS06350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPB73_RS06350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LPB73_RS06355	COG0509	glycine decarboxylation via glycine cleavage system
LPB73_RS06360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LPB73_RS06365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPB73_RS06370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LPB73_RS06370	COG4651	solute:proton antiporter activity
LPB73_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS06385	COG1505	serine-type exopeptidase activity
LPB73_RS06390	COG0538	isocitrate dehydrogenase activity
LPB73_RS06425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LPB73_RS06450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS06455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS06460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS06460	COG1116	anion transmembrane transporter activity
LPB73_RS06465	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LPB73_RS06475	COG3708	Transcriptional regulator
LPB73_RS06475	COG2207	Transcriptional regulator
LPB73_RS06495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS06500	COG1840	ABC-type Fe3 transport system, periplasmic component
LPB73_RS06505	COG4774	siderophore transport
LPB73_RS06515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LPB73_RS06520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPB73_RS06525	COG0047	phosphoribosylformylglycinamidine synthase activity
LPB73_RS06530	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS06540	COG2610	gluconate transmembrane transporter activity
LPB73_RS06550	COG0583	DNA-binding transcription factor activity
LPB73_RS06570	COG4829	muconolactone delta-isomerase
LPB73_RS06580	COG0384	phenazine biosynthesis protein PhzF
LPB73_RS06595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LPB73_RS06620	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LPB73_RS06625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LPB73_RS06635	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LPB73_RS06650	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LPB73_RS06655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LPB73_RS06685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPB73_RS06720	COG3191	aminopeptidase activity
LPB73_RS06725	COG0785	Cytochrome C biogenesis protein
LPB73_RS06770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LPB73_RS06775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS06780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPB73_RS06815	COG3608	succinylglutamate desuccinylase aspartoacylase
LPB73_RS06815	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LPB73_RS06820	COG2068	MobA-Related Protein
LPB73_RS06860	COG0463	Glycosyl transferase, family 2
LPB73_RS06870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB73_RS06880	COG3186	Phenylalanine-4-hydroxylase
LPB73_RS06895	COG1959	2 iron, 2 sulfur cluster binding
LPB73_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS06965	COG0640	Transcriptional regulator
LPB73_RS06970	COG0251	oxidation-reduction process
LPB73_RS06975	COG0459	protein refolding
LPB73_RS06980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPB73_RS06985	COG5425	PFAM Usg family protein
LPB73_RS07000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LPB73_RS07005	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS07030	COG2308	Evidence 4 Homologs of previously reported genes of
LPB73_RS07035	COG1058	Belongs to the CinA family
LPB73_RS07035	COG1546	Belongs to the CinA family
LPB73_RS07040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LPB73_RS07050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPB73_RS07055	COG0625	glutathione transferase activity
LPB73_RS07075	COG1024	Enoyl-CoA hydratase
LPB73_RS07080	COG1473	amidohydrolase
LPB73_RS07095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS07100	COG0601	transmembrane transport
LPB73_RS07110	COG0747	negative chemotaxis
LPB73_RS07120	COG0747	negative chemotaxis
LPB73_RS07130	COG0251	oxidation-reduction process
LPB73_RS07135	COG0477	Major facilitator Superfamily
LPB73_RS07155	COG3395	kinase activity
LPB73_RS07160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LPB73_RS07165	COG1349	DNA-binding transcription factor activity
LPB73_RS07195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS07210	COG0596	Alpha beta hydrolase
LPB73_RS07225	COG2197	response regulator
LPB73_RS07445	COG3750	Belongs to the UPF0335 family
LPB73_RS07455	COG3756	Protein conserved in bacteria
LPB73_RS07630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LPB73_RS07735	COG1752	Esterase of the alpha-beta hydrolase superfamily
LPB73_RS07745	COG5001	Diguanylate cyclase
LPB73_RS07760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPB73_RS07765	COG2814	Major facilitator Superfamily
LPB73_RS07780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LPB73_RS07800	COG0302	gtp cyclohydrolase
LPB73_RS07805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LPB73_RS07840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPB73_RS07905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPB73_RS07940	COG0640	Transcriptional regulator
LPB73_RS07950	COG0785	Cytochrome C biogenesis protein
LPB73_RS07965	COG2010	Cytochrome c
LPB73_RS07970	COG3258	Cytochrome c
LPB73_RS07990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LPB73_RS08015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB73_RS08030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS08045	COG1176	ABC-type spermidine putrescine transport system, permease component I
LPB73_RS08050	COG1177	transmembrane transport
LPB73_RS08055	COG3842	ATPase activity
LPB73_RS08065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPB73_RS08070	COG1063	alcohol dehydrogenase
LPB73_RS08090	COG3706	GGDEF domain
LPB73_RS08115	COG4149	molybdate abc transporter
LPB73_RS08130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LPB73_RS08135	COG2723	6-phospho-beta-galactosidase activity
LPB73_RS08145	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LPB73_RS08160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS08165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS08170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPB73_RS08175	COG2011	ABC-type metal ion transport system permease component
LPB73_RS08180	COG1464	Belongs to the NlpA lipoprotein family
LPB73_RS08195	COG4221	oxidoreductase activity
LPB73_RS08245	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS08290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPB73_RS08320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LPB73_RS08330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPB73_RS08335	COG0081	regulation of translation
LPB73_RS08340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB73_RS08375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPB73_RS08380	COG0222	ribosome binding
LPB73_RS08385	COG0085	RNA polymerase activity
LPB73_RS08390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPB73_RS08405	COG1132	(ABC) transporter
LPB73_RS08415	COG0251	oxidation-reduction process
LPB73_RS08420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LPB73_RS08430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPB73_RS08435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPB73_RS08440	COG0051	transcription antitermination factor activity, RNA binding
LPB73_RS08445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LPB73_RS08450	COG0088	Forms part of the polypeptide exit tunnel
LPB73_RS08455	COG0089	rRNA binding
LPB73_RS08460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPB73_RS08465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPB73_RS08470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LPB73_RS08475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LPB73_RS08480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LPB73_RS08485	COG0255	Belongs to the universal ribosomal protein uL29 family
LPB73_RS08490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPB73_RS08495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPB73_RS08500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPB73_RS08505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPB73_RS08510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPB73_RS08515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPB73_RS08520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LPB73_RS08525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LPB73_RS08530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPB73_RS08535	COG1841	ribosomal large subunit assembly
LPB73_RS08540	COG0200	Binds to the 23S rRNA
LPB73_RS08545	COG0201	protein transport
LPB73_RS08550	COG0563	adenylate kinase activity
LPB73_RS08555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPB73_RS08560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPB73_RS08565	COG0202	RNA polymerase activity
LPB73_RS08570	COG0203	ribosomal protein L17
LPB73_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS08590	COG1733	regulation of RNA biosynthetic process
LPB73_RS08595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB73_RS08600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LPB73_RS08610	COG0778	Nitroreductase
LPB73_RS08630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPB73_RS08655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPB73_RS08680	COG2860	membrane
LPB73_RS08695	COG2267	carboxylic ester hydrolase activity
LPB73_RS08725	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LPB73_RS08740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LPB73_RS08745	COG1192	Involved in chromosome partitioning
LPB73_RS08765	COG1686	Belongs to the peptidase S11 family
LPB73_RS08780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LPB73_RS08820	COG1720	tRNA m6t6A37 methyltransferase activity
LPB73_RS08825	COG0537	adenosine 5'-monophosphoramidase activity
LPB73_RS08855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS08860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS08870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB73_RS08890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPB73_RS08900	COG0784	Response regulator, receiver
LPB73_RS08915	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LPB73_RS08920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS08925	COG0583	DNA-binding transcription factor activity
LPB73_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS08950	COG0557	exoribonuclease II activity
LPB73_RS08955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPB73_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS08980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LPB73_RS08985	COG1733	regulation of RNA biosynthetic process
LPB73_RS08990	COG0758	DNA mediated transformation
LPB73_RS09005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LPB73_RS09010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS09015	COG0540	Belongs to the ATCase OTCase family
LPB73_RS09025	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS09035	COG0679	Auxin Efflux Carrier
LPB73_RS09060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPB73_RS09070	COG0154	amidase activity
LPB73_RS09075	COG3920	Histidine kinase
LPB73_RS09095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS09105	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPB73_RS09125	COG2207	Transcriptional regulator
LPB73_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS09140	COG1335	isochorismatase
LPB73_RS09160	COG0741	lytic transglycosylase activity
LPB73_RS09165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB73_RS09170	COG1970	mechanosensitive ion channel activity
LPB73_RS09175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LPB73_RS09195	COG1758	RNA polymerase activity
LPB73_RS09205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LPB73_RS09210	COG0736	holo-[acyl-carrier-protein] synthase activity
LPB73_RS09215	COG0681	Belongs to the peptidase S26 family
LPB73_RS09220	COG0571	ribonuclease III activity
LPB73_RS09225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPB73_RS09235	COG1381	Involved in DNA repair and RecF pathway recombination
LPB73_RS09270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPB73_RS09275	COG1393	Belongs to the ArsC family
LPB73_RS09295	COG1253	flavin adenine dinucleotide binding
LPB73_RS09300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS09315	COG2814	Major facilitator Superfamily
LPB73_RS09330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LPB73_RS09340	COG1914	H( )-stimulated, divalent metal cation uptake system
LPB73_RS09360	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LPB73_RS09370	COG0113	porphobilinogen synthase activity
LPB73_RS09380	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS09415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPB73_RS09420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPB73_RS09425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPB73_RS09425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LPB73_RS09435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LPB73_RS09440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPB73_RS09445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LPB73_RS09450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LPB73_RS09470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LPB73_RS09475	COG0697	spore germination
LPB73_RS09505	COG2130	NADP-dependent
LPB73_RS09530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LPB73_RS09530	COG0519	Catalyzes the synthesis of GMP from XMP
LPB73_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS09560	COG0583	DNA-binding transcription factor activity
LPB73_RS09565	COG1049	propionate catabolic process, 2-methylcitrate cycle
LPB73_RS09630	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LPB73_RS09660	COG0242	peptide deformylase activity
LPB73_RS09670	COG0596	Alpha beta hydrolase
LPB73_RS09690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LPB73_RS09700	COG1846	Transcriptional regulator
LPB73_RS09710	COG1393	Belongs to the ArsC family
LPB73_RS09740	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS09745	COG4214	carbohydrate transport
LPB73_RS09750	COG1392	Phosphate transport regulator
LPB73_RS09755	COG0306	phosphate transporter
LPB73_RS09795	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS09805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LPB73_RS09830	COG2020	methyltransferase activity
LPB73_RS09845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS09850	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
LPB73_RS09890	COG0300	oxidoreductase activity
LPB73_RS09895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LPB73_RS09900	COG1286	toxin biosynthetic process
LPB73_RS09925	COG3300	MHYT domain
LPB73_RS09925	COG5001	Diguanylate cyclase
LPB73_RS09940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPB73_RS09945	COG0305	Participates in initiation and elongation during chromosome replication
LPB73_RS09955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LPB73_RS09965	COG0359	binds to the 23S rRNA
LPB73_RS09975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPB73_RS09980	COG0360	Binds together with S18 to 16S ribosomal RNA
LPB73_RS09985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LPB73_RS10000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPB73_RS10005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPB73_RS10010	COG1561	YicC-like family, N-terminal region
LPB73_RS10015	COG0194	GDP metabolic process
LPB73_RS10030	COG3842	ATPase activity
LPB73_RS10040	COG1178	ABC-type Fe3 transport system permease component
LPB73_RS10070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LPB73_RS10075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LPB73_RS10085	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LPB73_RS10100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LPB73_RS10115	COG0488	(ABC) transporter
LPB73_RS10130	COG0105	UTP biosynthetic process
LPB73_RS10135	COG0861	Integral membrane protein TerC family
LPB73_RS10145	COG1278	Cold shock
LPB73_RS10155	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LPB73_RS10160	COG1309	transcriptional regulator
LPB73_RS10170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS10180	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LPB73_RS10185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LPB73_RS10200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LPB73_RS10215	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LPB73_RS10220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LPB73_RS10235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LPB73_RS10240	COG0280	phosphate acetyltransferase
LPB73_RS10240	COG0281	malic enzyme
LPB73_RS10260	COG0386	Belongs to the glutathione peroxidase family
LPB73_RS10270	COG3045	CreA protein
LPB73_RS10340	COG1285	pathogenesis
LPB73_RS10345	COG0513	Belongs to the DEAD box helicase family
LPB73_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS10355	COG2814	Major facilitator Superfamily
LPB73_RS10365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS10405	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS10425	COG4753	response regulator
LPB73_RS10425	COG2207	Transcriptional regulator
LPB73_RS10440	COG0625	glutathione transferase activity
LPB73_RS10475	COG0789	Transcriptional regulator
LPB73_RS10485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPB73_RS10495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LPB73_RS10505	COG1309	transcriptional regulator
LPB73_RS10550	COG2837	iron assimilation
LPB73_RS10620	COG1304	FMN binding
LPB73_RS10655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPB73_RS10660	COG0697	spore germination
LPB73_RS10665	COG3038	cytochrome b561
LPB73_RS10675	COG2205	protein histidine kinase activity
LPB73_RS10695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LPB73_RS10700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LPB73_RS10705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LPB73_RS10710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS10725	COG0657	acetylesterase activity
LPB73_RS10740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LPB73_RS10745	COG1252	NADH dehydrogenase
LPB73_RS10750	COG0471	metal ion transport
LPB73_RS10755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPB73_RS10780	COG3920	Histidine kinase
LPB73_RS10785	COG0784	Response regulator, receiver
LPB73_RS10790	COG5002	protein histidine kinase activity
LPB73_RS10805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LPB73_RS10825	COG4993	Dehydrogenase
LPB73_RS10845	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LPB73_RS10875	COG0436	Aminotransferase
LPB73_RS10880	COG1268	BioY protein
LPB73_RS10885	COG1301	dicarboxylic acid transport
LPB73_RS10890	COG1530	ribonuclease E activity
LPB73_RS10890	COG1530	ribonuclease E activity
LPB73_RS10895	COG0860	N-Acetylmuramoyl-L-alanine amidase
LPB73_RS10900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LPB73_RS10925	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS10935	COG2192	nodulation
LPB73_RS10940	COG0739	heme binding
LPB73_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS10985	COG0840	transmembrane signaling receptor activity
LPB73_RS10995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPB73_RS11000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LPB73_RS11010	COG2945	thiolester hydrolase activity
LPB73_RS11015	COG1104	cysteine desulfurase activity
LPB73_RS11020	COG0719	Fe-S assembly protein
LPB73_RS11030	COG0396	ATPase activity
LPB73_RS11035	COG0719	Fe-S assembly protein
LPB73_RS11040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LPB73_RS11050	COG0316	Belongs to the HesB IscA family
LPB73_RS11060	COG3706	GGDEF domain
LPB73_RS11065	COG0513	Belongs to the DEAD box helicase family
LPB73_RS11090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS11110	COG0187	DNA topoisomerase II activity
LPB73_RS11120	COG0586	Pfam SNARE associated Golgi protein
LPB73_RS11140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LPB73_RS11150	COG0174	glutamine synthetase
LPB73_RS11160	COG2066	Belongs to the glutaminase family
LPB73_RS11170	COG3243	poly(R)-hydroxyalkanoic acid synthase
LPB73_RS11180	COG0436	Aminotransferase
LPB73_RS11200	COG0546	phosphoglycolate phosphatase activity
LPB73_RS11205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LPB73_RS11210	COG2188	Transcriptional regulator
LPB73_RS11215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPB73_RS11225	COG0114	fumarate hydratase activity
LPB73_RS11235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPB73_RS11240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LPB73_RS11245	COG1509	lysine 2,3-aminomutase activity
LPB73_RS11305	COG0625	glutathione transferase activity
LPB73_RS11400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LPB73_RS11430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPB73_RS11445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS11480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS11505	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LPB73_RS11530	COG4771	TonB-dependent receptor
LPB73_RS11535	COG4178	(ABC) transporter
LPB73_RS11570	COG2373	Large extracellular alpha-helical protein
LPB73_RS11575	COG4953	penicillin-binding protein 1C
LPB73_RS11590	COG0463	Glycosyl transferase, family 2
LPB73_RS11600	COG0626	cystathionine gamma-synthase activity
LPB73_RS11605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB73_RS11610	COG4597	amino acid ABC transporter
LPB73_RS11615	COG0765	amino acid transport
LPB73_RS11620	COG1126	abc transporter atp-binding protein
LPB73_RS11625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LPB73_RS11630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LPB73_RS11635	COG1538	Outer membrane efflux protein
LPB73_RS11645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB73_RS11685	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS11690	COG1129	ABC transporter
LPB73_RS11710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LPB73_RS11725	COG0525	valine-tRNA ligase activity
LPB73_RS11730	COG2094	Belongs to the DNA glycosylase MPG family
LPB73_RS11735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LPB73_RS11740	COG2867	negative regulation of translational initiation
LPB73_RS11750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LPB73_RS11750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LPB73_RS11770	COG5000	phosphorelay sensor kinase activity
LPB73_RS11775	COG2204	response regulator
LPB73_RS11785	COG1923	regulation of RNA biosynthetic process
LPB73_RS11790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LPB73_RS11800	COG3956	TIGRFAM MazG family protein
LPB73_RS11805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LPB73_RS11810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB73_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS11820	COG2186	Transcriptional regulator
LPB73_RS11825	COG0277	FAD linked oxidase domain protein
LPB73_RS11840	COG3005	denitrification pathway
LPB73_RS11850	COG0243	molybdopterin cofactor binding
LPB73_RS11860	COG4459	periplasmic nitrate reductase
LPB73_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS11905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS11910	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LPB73_RS11915	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS11925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LPB73_RS11925	COG0321	lipoyl(octanoyl) transferase activity
LPB73_RS11930	COG0084	hydrolase, TatD family'
LPB73_RS11935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB73_RS11945	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LPB73_RS11950	COG1686	Belongs to the peptidase S11 family
LPB73_RS12030	COG0583	DNA-binding transcription factor activity
LPB73_RS12055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB73_RS12060	COG0154	amidase activity
LPB73_RS12080	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LPB73_RS12085	COG1522	sequence-specific DNA binding
LPB73_RS12095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LPB73_RS12105	COG1984	allophanate hydrolase subunit 2
LPB73_RS12110	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LPB73_RS12115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LPB73_RS12125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS12130	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS12135	COG1116	anion transmembrane transporter activity
LPB73_RS12140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS12145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS12150	COG1116	anion transmembrane transporter activity
LPB73_RS12170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LPB73_RS12180	COG0175	sulfate reduction
LPB73_RS12185	COG0175	sulfate reduction
LPB73_RS12190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS12190	COG1116	anion transmembrane transporter activity
LPB73_RS12195	COG3707	response regulator
LPB73_RS12200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPB73_RS12215	COG1253	flavin adenine dinucleotide binding
LPB73_RS12220	COG1183	phosphatidylcholine synthase activity
LPB73_RS12225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS12230	COG0679	Auxin Efflux Carrier
LPB73_RS12265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPB73_RS12285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LPB73_RS12295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPB73_RS12330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPB73_RS12345	COG0697	spore germination
LPB73_RS12365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB73_RS12370	COG0343	queuine tRNA-ribosyltransferase activity
LPB73_RS12375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LPB73_RS12410	COG3158	transport of potassium into the cell
LPB73_RS12415	COG0583	DNA-binding transcription factor activity
LPB73_RS12420	COG1335	isochorismatase
LPB73_RS12425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPB73_RS12455	COG0629	single-stranded DNA binding
LPB73_RS12465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LPB73_RS12530	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LPB73_RS12555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LPB73_RS12560	COG1862	Preprotein translocase
LPB73_RS12570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPB73_RS12580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LPB73_RS12590	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LPB73_RS12600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LPB73_RS12610	COG0805	protein transport
LPB73_RS12615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPB73_RS12620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LPB73_RS12625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPB73_RS12630	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LPB73_RS12635	COG1472	Belongs to the glycosyl hydrolase 3 family
LPB73_RS12645	COG0018	arginyl-trna synthetase
LPB73_RS12650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LPB73_RS12680	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LPB73_RS12685	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS12695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB73_RS12705	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB73_RS12715	COG0022	dehydrogenase e1 component
LPB73_RS12715	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB73_RS12720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LPB73_RS12730	COG0431	NADPH-dependent FMN reductase
LPB73_RS12740	COG1280	lysine exporter protein (LysE YggA)
LPB73_RS12755	COG2020	methyltransferase activity
LPB73_RS12795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LPB73_RS12810	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LPB73_RS12840	COG0504	CTP synthase activity
LPB73_RS12850	COG0149	triose-phosphate isomerase activity
LPB73_RS12870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LPB73_RS12875	COG0134	indole-3-glycerol-phosphate synthase activity
LPB73_RS12880	COG0315	cyclic pyranopterin monophosphate synthase activity
LPB73_RS12905	COG2124	cytochrome p450
LPB73_RS12915	COG1011	Hydrolase
LPB73_RS12940	COG1982	Orn Lys Arg decarboxylase major
LPB73_RS12945	COG0456	acetyltransferase
LPB73_RS12950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPB73_RS12960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPB73_RS12965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPB73_RS12970	COG0372	Belongs to the citrate synthase family
LPB73_RS12975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB73_RS12985	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB73_RS12990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPB73_RS12995	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LPB73_RS13000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPB73_RS13005	COG0750	zinc metalloprotease
LPB73_RS13010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LPB73_RS13020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPB73_RS13025	COG0233	cytoplasmic translational termination
LPB73_RS13030	COG0528	UMP kinase activity
LPB73_RS13035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPB73_RS13040	COG0052	Belongs to the universal ribosomal protein uS2 family
LPB73_RS13055	COG1136	(ABC) transporter
LPB73_RS13065	COG0442	prolyl-tRNA aminoacylation
LPB73_RS13080	COG0346	lactoylglutathione lyase activity
LPB73_RS13095	COG1007	ATP synthesis coupled electron transport
LPB73_RS13110	COG0713	ATP synthesis coupled electron transport
LPB73_RS13120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LPB73_RS13125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LPB73_RS13135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LPB73_RS13145	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LPB73_RS13155	COG0649	NAD binding
LPB73_RS13165	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LPB73_RS13195	COG0776	regulation of translation
LPB73_RS13200	COG2195	Cleaves the N-terminal amino acid of tripeptides
LPB73_RS13205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS13215	COG2197	response regulator
LPB73_RS13220	COG3916	Acyl-homoserine-lactone synthase
LPB73_RS13240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LPB73_RS13245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LPB73_RS13250	COG0740	serine-type endopeptidase activity
LPB73_RS13255	COG0544	peptidyl-prolyl cis-trans isomerase activity
LPB73_RS13270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LPB73_RS13270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LPB73_RS13275	COG0347	Belongs to the P(II) protein family
LPB73_RS13280	COG0174	glutamine synthetase
LPB73_RS13295	COG0628	permease
LPB73_RS13315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LPB73_RS13320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPB73_RS13330	COG1024	Enoyl-CoA hydratase
LPB73_RS13345	COG0672	)-iron permease
LPB73_RS13350	COG1612	heme a metabolic process
LPB73_RS13420	COG0776	regulation of translation
LPB73_RS13425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB73_RS13430	COG0416	fatty acid biosynthetic process
LPB73_RS13450	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS13480	COG1671	Belongs to the UPF0178 family
LPB73_RS13485	COG0488	(ABC) transporter
LPB73_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS13510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPB73_RS13525	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS13540	COG1024	Enoyl-CoA hydratase
LPB73_RS13540	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS13545	COG0183	Belongs to the thiolase family
LPB73_RS13550	COG2271	Major facilitator Superfamily
LPB73_RS13555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPB73_RS13560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LPB73_RS13590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LPB73_RS13660	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS13685	COG2030	dehydratase
LPB73_RS13735	COG0656	L-ascorbic acid biosynthetic process
LPB73_RS13770	COG2239	Acts as a magnesium transporter
LPB73_RS13815	COG0321	lipoyl(octanoyl) transferase activity
LPB73_RS13820	COG1254	Belongs to the acylphosphatase family
LPB73_RS13825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LPB73_RS13830	COG4770	biotin carboxylase activity
LPB73_RS13850	COG0450	alkyl hydroperoxide reductase
LPB73_RS13855	COG0415	Belongs to the DNA photolyase family
LPB73_RS13865	COG0697	spore germination
LPB73_RS13870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LPB73_RS13875	COG0045	succinate-CoA ligase (ADP-forming) activity
LPB73_RS13875	COG1042	CoA-binding domain protein
LPB73_RS13875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPB73_RS13885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LPB73_RS13895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS13900	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS13905	COG0183	Belongs to the thiolase family
LPB73_RS13910	COG0800	Aldolase
LPB73_RS13915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB73_RS13920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB73_RS13925	COG0395	ABC-type sugar transport system, permease component
LPB73_RS13945	COG3842	ATPase activity
LPB73_RS13950	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS13955	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS13960	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS13970	COG0848	biopolymer transport protein
LPB73_RS13980	COG3128	pkhd-type hydroxylase
LPB73_RS13985	COG4774	siderophore transport
LPB73_RS13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS14020	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LPB73_RS14025	COG0840	transmembrane signaling receptor activity
LPB73_RS14030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LPB73_RS14035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LPB73_RS14040	COG0367	asparagine synthase
LPB73_RS14045	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS14050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPB73_RS14055	COG2890	protein-(glutamine-N5) methyltransferase activity
LPB73_RS14070	COG1953	Uracil, thiamine, allantoin
LPB73_RS14090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LPB73_RS14105	COG0583	DNA-binding transcription factor activity
LPB73_RS14120	COG1285	pathogenesis
LPB73_RS14135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPB73_RS14140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPB73_RS14150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LPB73_RS14155	COG0604	alcohol dehydrogenase
LPB73_RS14155	COG3321	synthase
LPB73_RS14160	COG1560	Kdo2-lipid A biosynthetic process
LPB73_RS14165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LPB73_RS14170	COG0436	Aminotransferase
LPB73_RS14180	COG3158	transport of potassium into the cell
LPB73_RS14185	COG3158	transport of potassium into the cell
LPB73_RS14195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LPB73_RS14210	COG1183	phosphatidylcholine synthase activity
LPB73_RS14215	COG0688	phosphatidylethanolamine metabolic process
LPB73_RS14220	COG5265	(ABC) transporter
LPB73_RS14240	COG0215	cysteine-tRNA ligase activity
LPB73_RS14265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LPB73_RS14270	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LPB73_RS14290	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LPB73_RS14295	COG0546	phosphoglycolate phosphatase activity
LPB73_RS14305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LPB73_RS14330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LPB73_RS14335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LPB73_RS14340	COG0489	protein tyrosine kinase activity
LPB73_RS14345	COG2084	Dehydrogenase
LPB73_RS14350	COG2202	Pas domain
LPB73_RS14350	COG2205	protein histidine kinase activity
LPB73_RS14375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB73_RS14380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS14430	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS14435	COG1024	Enoyl-CoA hydratase
LPB73_RS14440	COG0596	Alpha beta hydrolase
LPB73_RS14450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS14465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPB73_RS14475	COG1802	Transcriptional regulator
LPB73_RS14485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS14545	COG3321	synthase
LPB73_RS14545	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS14545	COG0604	alcohol dehydrogenase
LPB73_RS14550	COG2205	protein histidine kinase activity
LPB73_RS14550	COG2202	Pas domain
LPB73_RS14555	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS14560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LPB73_RS14565	COG2205	protein histidine kinase activity
LPB73_RS14595	COG0745	RESPONSE REGULATOR receiver
LPB73_RS14620	COG1802	Transcriptional regulator
LPB73_RS14630	COG2197	response regulator
LPB73_RS14635	COG2205	protein histidine kinase activity
LPB73_RS14635	COG0784	Response regulator, receiver
LPB73_RS14645	COG3088	subunit of a heme lyase
LPB73_RS14650	COG1138	Cytochrome C-type biogenesis protein
LPB73_RS14655	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LPB73_RS14660	COG4235	cytochrome complex assembly
LPB73_RS14665	COG0625	glutathione transferase activity
LPB73_RS14670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPB73_RS14670	COG1017	nitric oxide dioxygenase activity
LPB73_RS14770	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS14870	COG1222	aaa ATPase
LPB73_RS14950	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LPB73_RS14955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB73_RS14960	COG4695	Portal protein
LPB73_RS14995	COG0583	DNA-binding transcription factor activity
LPB73_RS15010	COG2814	Major facilitator Superfamily
LPB73_RS15015	COG2983	Belongs to the UPF0260 family
LPB73_RS15020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LPB73_RS15090	COG2205	protein histidine kinase activity
LPB73_RS15100	COG2166	iron-sulfur cluster assembly
LPB73_RS15105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPB73_RS15115	COG4957	zinc ion binding
LPB73_RS15160	COG4977	sequence-specific DNA binding
LPB73_RS15165	COG0235	Class ii aldolase
LPB73_RS15185	COG0433	COG0433 Predicted ATPase
LPB73_RS15200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LPB73_RS15210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LPB73_RS15245	COG1703	isobutyryl-CoA mutase activity
LPB73_RS15250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LPB73_RS15255	COG2814	Major facilitator Superfamily
LPB73_RS15275	COG1404	Belongs to the peptidase S8 family
LPB73_RS15300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB73_RS15305	COG0492	ferredoxin-NADP+ reductase activity
LPB73_RS15330	COG0427	acetyl-CoA hydrolase
LPB73_RS15340	COG4251	negative regulation of phosphorylation
LPB73_RS15355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS15365	COG0587	DNA-directed DNA polymerase activity
LPB73_RS15385	COG1573	uracil-dna glycosylase
LPB73_RS15395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB73_RS15400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS15420	COG0673	inositol 2-dehydrogenase activity
LPB73_RS15430	COG1116	anion transmembrane transporter activity
LPB73_RS15440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS15445	COG1309	transcriptional regulator
LPB73_RS15470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB73_RS15475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB73_RS15480	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS15485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB73_RS15490	COG3386	PFAM SMP-30 Gluconolaconase
LPB73_RS15505	COG2010	Cytochrome c
LPB73_RS15515	COG3909	cytochrome
LPB73_RS15525	COG0728	peptidoglycan biosynthetic process
LPB73_RS15535	COG0673	inositol 2-dehydrogenase activity
LPB73_RS15565	COG2274	protein secretion by the type I secretion system
LPB73_RS15570	COG1538	Outer membrane efflux protein
LPB73_RS15575	COG0662	Cupin 2, conserved barrel domain protein
LPB73_RS15575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LPB73_RS15590	COG1086	Polysaccharide biosynthesis protein
LPB73_RS15595	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LPB73_RS15595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LPB73_RS15605	COG0859	PFAM glycosyl transferase family 9
LPB73_RS15610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LPB73_RS15625	COG2207	Transcriptional regulator
LPB73_RS15630	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB73_RS15635	COG1132	(ABC) transporter
LPB73_RS15645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS15655	COG1404	Belongs to the peptidase S8 family
LPB73_RS15660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LPB73_RS15665	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LPB73_RS15675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LPB73_RS15680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LPB73_RS15685	COG0410	ABC transporter
LPB73_RS15745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LPB73_RS15745	COG2755	lipolytic protein G-D-S-L family
LPB73_RS15760	COG0457	Tetratricopeptide repeat
LPB73_RS15760	COG3710	Transcriptional regulator
LPB73_RS15780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS15800	COG0411	ABC transporter
LPB73_RS15820	COG1022	Amp-dependent synthetase and ligase
LPB73_RS15825	COG2852	Protein conserved in bacteria
LPB73_RS15830	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS15865	COG2942	2-epimerase
LPB73_RS15900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPB73_RS15905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LPB73_RS15915	COG2226	methyltransferase
LPB73_RS15925	COG0463	Glycosyl transferase, family 2
LPB73_RS15930	COG0367	asparagine synthase
LPB73_RS15955	COG1216	Glycosyl transferase, family 2
LPB73_RS15955	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS15975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LPB73_RS15980	COG1091	dTDP-4-dehydrorhamnose reductase activity
LPB73_RS15985	COG1088	dTDP-glucose 4,6-dehydratase activity
LPB73_RS15990	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LPB73_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS16030	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LPB73_RS16030	COG0546	phosphoglycolate phosphatase activity
LPB73_RS16035	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS16035	COG1216	Glycosyl transferase, family 2
LPB73_RS16065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS16085	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS16090	COG1024	Enoyl-CoA hydratase
LPB73_RS16095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LPB73_RS16100	COG0277	FAD linked oxidase domain protein
LPB73_RS16100	COG0247	lactate metabolic process
LPB73_RS16110	COG1408	metallophosphoesterase
LPB73_RS16115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB73_RS16125	COG0463	Glycosyl transferase, family 2
LPB73_RS16140	COG1024	Enoyl-CoA hydratase
LPB73_RS16150	COG2755	lipolytic protein G-D-S-L family
LPB73_RS16150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LPB73_RS16170	COG1414	Transcriptional regulator
LPB73_RS16180	COG1176	ABC-type spermidine putrescine transport system, permease component I
LPB73_RS16185	COG3842	ATPase activity
LPB73_RS16210	COG0235	Class ii aldolase
LPB73_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS16265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LPB73_RS16275	COG2326	polyphosphate kinase activity
LPB73_RS16290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LPB73_RS16295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS16305	COG0517	IMP dehydrogenase activity
LPB73_RS16305	COG1125	glycine betaine transport
LPB73_RS16310	COG1174	glycine betaine transport
LPB73_RS16330	COG2186	Transcriptional regulator
LPB73_RS16335	COG0300	oxidoreductase activity
LPB73_RS16345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LPB73_RS16360	COG0440	acetolactate synthase activity
LPB73_RS16365	COG0028	Belongs to the TPP enzyme family
LPB73_RS16370	COG3093	addiction module antidote protein HigA
LPB73_RS16375	COG3549	Plasmid maintenance system killer
LPB73_RS16380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPB73_RS16385	COG0560	Phosphoserine phosphatase
LPB73_RS16400	COG0330	HflC and HflK could
LPB73_RS16405	COG0330	HflC and HflK could
LPB73_RS16415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LPB73_RS16450	COG0114	fumarate hydratase activity
LPB73_RS16470	COG2271	Major facilitator Superfamily
LPB73_RS16475	COG0277	FAD linked oxidase domain protein
LPB73_RS16485	COG5487	UPF0391 membrane protein
LPB73_RS16490	COG0210	DNA helicase
LPB73_RS16500	COG1131	(ABC) transporter
LPB73_RS16505	COG0842	Transport permease protein
LPB73_RS16525	COG1233	COG1233 Phytoene dehydrogenase and related
LPB73_RS16530	COG2264	protein methyltransferase activity
LPB73_RS16540	COG0006	proline dipeptidase activity
LPB73_RS16540	COG0006	proline dipeptidase activity
LPB73_RS16545	COG2814	Major facilitator Superfamily
LPB73_RS16560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LPB73_RS16570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPB73_RS16575	COG0849	cell division
LPB73_RS16580	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LPB73_RS16585	COG1181	Belongs to the D-alanine--D-alanine ligase family
LPB73_RS16595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LPB73_RS16600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LPB73_RS16605	COG2814	Major facilitator Superfamily
LPB73_RS16610	COG0583	DNA-binding transcription factor activity
LPB73_RS16620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPB73_RS16630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPB73_RS16635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPB73_RS16645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LPB73_RS16665	COG3023	N-Acetylmuramoyl-L-alanine amidase
LPB73_RS16670	COG4941	Belongs to the sigma-70 factor family
LPB73_RS16675	COG3795	YCII-related domain
LPB73_RS16695	COG5265	(ABC) transporter
LPB73_RS16710	COG1309	transcriptional regulator
LPB73_RS16720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS16730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS16735	COG1388	LysM domain
LPB73_RS16735	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS16795	COG2022	thiamine diphosphate biosynthetic process
LPB73_RS16805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LPB73_RS16820	COG2204	response regulator
LPB73_RS16845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS16905	COG4106	trans-aconitate 2-methyltransferase activity
LPB73_RS16920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB73_RS16925	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS16935	COG2897	thiosulfate sulfurtransferase activity
LPB73_RS16950	COG2203	Gaf domain
LPB73_RS16950	COG4251	negative regulation of phosphorylation
LPB73_RS16950	COG3706	GGDEF domain
LPB73_RS16950	COG5001	Diguanylate cyclase
LPB73_RS16960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPB73_RS16975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LPB73_RS16980	COG2814	Major facilitator Superfamily
LPB73_RS17000	COG1024	Enoyl-CoA hydratase
LPB73_RS17050	COG2207	Transcriptional regulator
LPB73_RS17080	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS17085	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS17090	COG1137	ATPase activity
LPB73_RS17095	COG0410	ABC transporter
LPB73_RS17115	COG1024	Enoyl-CoA hydratase
LPB73_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS17140	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS17145	COG2267	carboxylic ester hydrolase activity
LPB73_RS17160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LPB73_RS17165	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS17170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS17175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS17190	COG0386	Belongs to the glutathione peroxidase family
LPB73_RS17195	COG0154	amidase activity
LPB73_RS17220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LPB73_RS17230	COG0535	radical SAM domain protein
LPB73_RS17235	COG0535	radical SAM domain protein
LPB73_RS17260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LPB73_RS17265	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LPB73_RS17270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPB73_RS17275	COG0363	glucosamine-6-phosphate deaminase activity
LPB73_RS17280	COG3265	gluconokinase activity
LPB73_RS17290	COG3387	PFAM Glycoside hydrolase 15-related
LPB73_RS17295	COG1640	4-alpha-glucanotransferase
LPB73_RS17300	COG0366	Alpha amylase catalytic
LPB73_RS17305	COG0366	Alpha amylase catalytic
LPB73_RS17310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LPB73_RS17320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LPB73_RS17345	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LPB73_RS17365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB73_RS17385	COG2223	nitrite transmembrane transporter activity
LPB73_RS17390	COG0425	Belongs to the sulfur carrier protein TusA family
LPB73_RS17395	COG0746	molybdenum cofactor guanylyltransferase activity
LPB73_RS17490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPB73_RS17510	COG1595	DNA-templated transcription, initiation
LPB73_RS17530	COG3766	membrane
LPB73_RS17540	COG0754	glutathionylspermidine amidase activity
LPB73_RS17550	COG2201	protein-glutamate methylesterase activity
LPB73_RS17565	COG0643	Histidine kinase
LPB73_RS17565	COG0784	Response regulator, receiver
LPB73_RS17565	COG2198	Histidine kinase
LPB73_RS17600	COG1024	Enoyl-CoA hydratase
LPB73_RS17610	COG0183	Belongs to the thiolase family
LPB73_RS17620	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS17630	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS17650	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS17665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS17675	COG1024	Enoyl-CoA hydratase
LPB73_RS17680	COG2814	Major facilitator Superfamily
LPB73_RS17685	COG0583	DNA-binding transcription factor activity
LPB73_RS17700	COG1079	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS17710	COG3845	ABC transporter
LPB73_RS17715	COG1744	ABC transporter substrate-binding protein PnrA-like
LPB73_RS17720	COG1414	Transcriptional regulator
LPB73_RS17725	COG2072	flavoprotein involved in K transport
LPB73_RS17735	COG3842	ATPase activity
LPB73_RS17760	COG0405	Gamma-glutamyltransferase
LPB73_RS17775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS17780	COG0601	transmembrane transport
LPB73_RS17785	COG0747	negative chemotaxis
LPB73_RS17815	COG0673	inositol 2-dehydrogenase activity
LPB73_RS17820	COG3842	ATPase activity
LPB73_RS17830	COG1175	transmembrane transport
LPB73_RS17840	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS17860	COG0411	ABC transporter
LPB73_RS17870	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS17890	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS17895	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS17925	COG2072	flavoprotein involved in K transport
LPB73_RS17950	COG0681	Belongs to the peptidase S26 family
LPB73_RS17975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LPB73_RS17985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB73_RS18020	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS18035	COG0747	negative chemotaxis
LPB73_RS18040	COG4608	Belongs to the ABC transporter superfamily
LPB73_RS18045	COG0444	Belongs to the ABC transporter superfamily
LPB73_RS18055	COG1802	Transcriptional regulator
LPB73_RS18075	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS18080	COG0667	Aldo Keto reductase
LPB73_RS18095	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS18100	COG0505	Belongs to the CarA family
LPB73_RS18105	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS18125	COG0583	DNA-binding transcription factor activity
LPB73_RS18155	COG1802	Transcriptional regulator
LPB73_RS18160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB73_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS18170	COG2072	flavoprotein involved in K transport
LPB73_RS18175	COG0747	negative chemotaxis
LPB73_RS18180	COG0601	transmembrane transport
LPB73_RS18185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS18200	COG4172	Belongs to the ABC transporter superfamily
LPB73_RS18205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS18210	COG0601	transmembrane transport
LPB73_RS18215	COG0747	negative chemotaxis
LPB73_RS18250	COG0028	Belongs to the TPP enzyme family
LPB73_RS18255	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS18290	COG2368	4-hydroxyphenylacetate
LPB73_RS18305	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS18330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS18350	COG0753	catalase activity
LPB73_RS18355	COG0747	negative chemotaxis
LPB73_RS18360	COG0601	transmembrane transport
LPB73_RS18365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS18370	COG4172	Belongs to the ABC transporter superfamily
LPB73_RS18375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS18390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPB73_RS18395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LPB73_RS18420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LPB73_RS18450	COG3206	protein involved in exopolysaccharide biosynthesis
LPB73_RS18450	COG0489	protein tyrosine kinase activity
LPB73_RS18495	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS18520	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LPB73_RS18530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS18555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS18560	COG0601	transmembrane transport
LPB73_RS18565	COG0747	negative chemotaxis
LPB73_RS18570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS18590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS18595	COG1116	anion transmembrane transporter activity
LPB73_RS18610	COG1464	Belongs to the NlpA lipoprotein family
LPB73_RS18615	COG1045	serine acetyltransferase
LPB73_RS18660	COG1216	Glycosyl transferase, family 2
LPB73_RS18690	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS18695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LPB73_RS18700	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS18710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS18715	COG4310	Domain of unknown function (DUF2172)
LPB73_RS18725	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LPB73_RS18730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LPB73_RS18740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB73_RS18755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB73_RS18760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LPB73_RS18780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB73_RS18785	COG0765	amino acid transport
LPB73_RS18790	COG0765	amino acid transport
LPB73_RS18800	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS18805	COG1126	abc transporter atp-binding protein
LPB73_RS18810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS18825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LPB73_RS18835	COG0523	cobalamin synthesis protein
LPB73_RS18845	COG0601	transmembrane transport
LPB73_RS18850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS18855	COG0444	Belongs to the ABC transporter superfamily
LPB73_RS18860	COG4608	Belongs to the ABC transporter superfamily
LPB73_RS18895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB73_RS18910	COG0564	pseudouridine synthase activity
LPB73_RS18915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB73_RS18925	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LPB73_RS18930	COG0830	nickel cation binding
LPB73_RS18935	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LPB73_RS18945	COG0804	urea catabolic process
LPB73_RS18950	COG2852	Protein conserved in bacteria
LPB73_RS18960	COG0832	Belongs to the urease beta subunit family
LPB73_RS18965	COG0831	urea catabolic process
LPB73_RS18970	COG0829	nickel cation binding
LPB73_RS18980	COG1129	ABC transporter
LPB73_RS19000	COG0513	Belongs to the DEAD box helicase family
LPB73_RS19005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPB73_RS19010	COG1278	Cold shock
LPB73_RS19050	COG4964	Belongs to the GSP D family
LPB73_RS19085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LPB73_RS19100	COG4172	Belongs to the ABC transporter superfamily
LPB73_RS19105	COG4239	(ABC) transporter, permease
LPB73_RS19110	COG4174	ABC transporter (Permease)
LPB73_RS19115	COG4166	transmembrane transport
LPB73_RS19120	COG4166	transmembrane transport
LPB73_RS19125	COG3474	cytochrome
LPB73_RS19130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LPB73_RS19135	COG1605	Chorismate mutase
LPB73_RS19135	COG0077	Prephenate dehydratase
LPB73_RS19140	COG3795	YCII-related domain
LPB73_RS19150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS19170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LPB73_RS19175	COG0445	tRNA wobble uridine modification
LPB73_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS19190	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS19195	COG0183	Belongs to the thiolase family
LPB73_RS19200	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS19280	COG4106	trans-aconitate 2-methyltransferase activity
LPB73_RS19295	COG2186	Transcriptional regulator
LPB73_RS19305	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS19310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS19315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS19340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB73_RS19355	COG2207	Transcriptional regulator
LPB73_RS19400	COG2514	catechol 2,3-dioxygenase activity
LPB73_RS19410	COG4774	siderophore transport
LPB73_RS19420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPB73_RS19435	COG2202	Pas domain
LPB73_RS19435	COG3920	Histidine kinase
LPB73_RS19440	COG4191	Histidine kinase
LPB73_RS19440	COG0784	Response regulator, receiver
LPB73_RS19450	COG1278	Cold shock
LPB73_RS19460	COG0384	phenazine biosynthesis protein PhzF
LPB73_RS19470	COG2140	Oxalate decarboxylase
LPB73_RS19490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPB73_RS19510	COG4774	siderophore transport
LPB73_RS19515	COG0840	transmembrane signaling receptor activity
LPB73_RS19515	COG3290	protein histidine kinase activity
LPB73_RS19550	COG0840	transmembrane signaling receptor activity
LPB73_RS19560	COG0840	transmembrane signaling receptor activity
LPB73_RS19565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB73_RS19570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LPB73_RS19580	COG0625	glutathione transferase activity
LPB73_RS19595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB73_RS19605	COG1304	FMN binding
LPB73_RS19620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPB73_RS19625	COG0659	secondary active sulfate transmembrane transporter activity
LPB73_RS19640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPB73_RS19655	COG0436	Aminotransferase
LPB73_RS19675	COG2133	pyrroloquinoline quinone binding
LPB73_RS19695	COG0667	Aldo Keto reductase
LPB73_RS19715	COG3706	GGDEF domain
LPB73_RS19725	COG0625	glutathione transferase activity
LPB73_RS19760	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LPB73_RS19770	COG0556	nucleotide-excision repair
LPB73_RS19795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB73_RS19800	COG1301	dicarboxylic acid transport
LPB73_RS19845	COG2030	dehydratase
LPB73_RS19855	COG0012	GTP binding
LPB73_RS19860	COG0193	aminoacyl-tRNA hydrolase activity
LPB73_RS19865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LPB73_RS19875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPB73_RS19885	COG1496	oxidoreductase activity
LPB73_RS19895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPB73_RS19900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LPB73_RS19910	COG0456	acetyltransferase
LPB73_RS19915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LPB73_RS19925	COG0745	RESPONSE REGULATOR receiver
LPB73_RS19930	COG1846	Transcriptional regulator
LPB73_RS19940	COG0534	Mate efflux family protein
LPB73_RS19950	COG2890	protein-(glutamine-N5) methyltransferase activity
LPB73_RS19955	COG0314	molybdopterin synthase activity
LPB73_RS19965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPB73_RS19970	COG0322	excinuclease ABC activity
LPB73_RS19980	COG1278	Cold shock
LPB73_RS19985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LPB73_RS20015	COG1942	4-Oxalocrotonate Tautomerase
LPB73_RS20020	COG0124	histidyl-tRNA synthetase
LPB73_RS20030	COG1295	ribonuclease BN
LPB73_RS20045	COG0745	RESPONSE REGULATOR receiver
LPB73_RS20050	COG0196	riboflavin kinase activity
LPB73_RS20060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPB73_RS20065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPB73_RS20075	COG0612	Peptidase, M16
LPB73_RS20080	COG0612	Peptidase, M16
LPB73_RS20085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPB73_RS20100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPB73_RS20110	COG0742	ribosomal rna small subunit methyltransferase
LPB73_RS20115	COG1187	pseudouridine synthase activity
LPB73_RS20120	COG0590	tRNA wobble adenosine to inosine editing
LPB73_RS20130	COG0151	Belongs to the GarS family
LPB73_RS20155	COG1570	exodeoxyribonuclease VII activity
LPB73_RS20165	COG1663	tetraacyldisaccharide 4'-kinase activity
LPB73_RS20170	COG1519	Transferase
LPB73_RS20185	COG0483	inositol monophosphate 1-phosphatase activity
LPB73_RS20190	COG0312	modulator of DNA gyrase
LPB73_RS20210	COG0277	FAD linked oxidase domain protein
LPB73_RS20220	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
LPB73_RS20220	COG0028	Belongs to the TPP enzyme family
LPB73_RS20230	COG0583	DNA-binding transcription factor activity
LPB73_RS20250	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LPB73_RS20255	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LPB73_RS20260	COG0463	Glycosyl transferase, family 2
LPB73_RS20285	COG3416	Protein conserved in bacteria
LPB73_RS20290	COG1388	LysM domain
LPB73_RS20290	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS20310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPB73_RS20315	COG0459	protein refolding
LPB73_RS20330	COG1620	l-lactate permease
LPB73_RS20335	COG4178	(ABC) transporter
LPB73_RS20355	COG0247	lactate metabolic process
LPB73_RS20360	COG0277	FAD linked oxidase domain protein
LPB73_RS20365	COG0277	FAD linked oxidase domain protein
LPB73_RS20370	COG3474	cytochrome
LPB73_RS20375	COG1309	transcriptional regulator
LPB73_RS20390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPB73_RS20395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LPB73_RS20395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPB73_RS20420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPB73_RS20425	COG0037	tRNA processing
LPB73_RS20435	COG2885	chlorophyll binding
LPB73_RS20445	COG5001	Diguanylate cyclase
LPB73_RS20450	COG0823	Involved in the tonB-independent uptake of proteins
LPB73_RS20460	COG0848	biopolymer transport protein
LPB73_RS20475	COG1309	transcriptional regulator
LPB73_RS20480	COG3795	YCII-related domain
LPB73_RS20495	COG0583	DNA-binding transcription factor activity
LPB73_RS20500	COG1335	isochorismatase
LPB73_RS20520	COG4774	siderophore transport
LPB73_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS20530	COG4774	siderophore transport
LPB73_RS20540	COG2814	Major facilitator Superfamily
LPB73_RS20555	COG4941	Belongs to the sigma-70 factor family
LPB73_RS20560	COG3795	YCII-related domain
LPB73_RS20570	COG0625	glutathione transferase activity
LPB73_RS20575	COG3639	organic phosphonate transmembrane transporter activity
LPB73_RS20580	COG3639	organic phosphonate transmembrane transporter activity
LPB73_RS20590	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LPB73_RS20600	COG3454	Phosphonate metabolism
LPB73_RS20605	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LPB73_RS20610	COG0523	cobalamin synthesis protein
LPB73_RS20615	COG2199	diguanylate cyclase activity
LPB73_RS20620	COG0405	Gamma-glutamyltransferase
LPB73_RS20640	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS20645	COG0583	DNA-binding transcription factor activity
LPB73_RS20650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LPB73_RS20665	COG4177	L-phenylalanine transmembrane transporter activity
LPB73_RS20680	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LPB73_RS20680	COG1082	Xylose isomerase domain protein TIM barrel
LPB73_RS20695	COG0482	sulfurtransferase activity
LPB73_RS20705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LPB73_RS20715	COG1766	The M ring may be actively involved in energy transduction
LPB73_RS20720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPB73_RS20730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPB73_RS20735	COG2204	response regulator
LPB73_RS20760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB73_RS20765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB73_RS20795	COG2951	lytic endotransglycosylase activity
LPB73_RS20825	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LPB73_RS20840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LPB73_RS20860	COG3253	May function as heme-dependent peroxidase
LPB73_RS20865	COG2814	Major facilitator Superfamily
LPB73_RS20890	COG1280	lysine exporter protein (LysE YggA)
LPB73_RS20900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPB73_RS20910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LPB73_RS20915	COG0475	glutathione-regulated potassium exporter activity
LPB73_RS20915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LPB73_RS20920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPB73_RS20920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LPB73_RS20925	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS20945	COG2706	6-phosphogluconolactonase activity
LPB73_RS20950	COG4774	siderophore transport
LPB73_RS20955	COG0864	Transcriptional regulator
LPB73_RS20960	COG0656	L-ascorbic acid biosynthetic process
LPB73_RS20965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS20975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LPB73_RS20975	COG0446	pyridine nucleotide-disulphide oxidoreductase
LPB73_RS20985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LPB73_RS20995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS21025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LPB73_RS21030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPB73_RS21045	COG0346	lactoylglutathione lyase activity
LPB73_RS21050	COG0683	leucine binding
LPB73_RS21085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LPB73_RS21085	COG0392	lysyltransferase activity
LPB73_RS21095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LPB73_RS21100	COG0395	ABC-type sugar transport system, permease component
LPB73_RS21110	COG3842	ATPase activity
LPB73_RS21125	COG2186	Transcriptional regulator
LPB73_RS21135	COG0009	L-threonylcarbamoyladenylate synthase
LPB73_RS21140	COG0277	FAD linked oxidase domain protein
LPB73_RS21145	COG0456	acetyltransferase
LPB73_RS21150	COG2135	peptidase activity
LPB73_RS21180	COG1024	Enoyl-CoA hydratase
LPB73_RS21195	COG1024	Enoyl-CoA hydratase
LPB73_RS21205	COG2072	flavoprotein involved in K transport
LPB73_RS21210	COG2070	2-Nitropropane dioxygenase
LPB73_RS21230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LPB73_RS21235	COG3395	kinase activity
LPB73_RS21240	COG3622	Belongs to the hyi family
LPB73_RS21245	COG2084	Dehydrogenase
LPB73_RS21250	COG0235	Class ii aldolase
LPB73_RS21290	COG4336	lyase activity
LPB73_RS21305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB73_RS21310	COG0473	3-isopropylmalate dehydrogenase activity
LPB73_RS21315	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS21320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LPB73_RS21335	COG1573	uracil-dna glycosylase
LPB73_RS21345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPB73_RS21370	COG0521	Mo-molybdopterin cofactor biosynthetic process
LPB73_RS21375	COG2321	neutral zinc metallopeptidase
LPB73_RS21380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LPB73_RS21385	COG0625	glutathione transferase activity
LPB73_RS21410	COG0840	transmembrane signaling receptor activity
LPB73_RS21420	COG1194	a g-specific adenine glycosylase
LPB73_RS21430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LPB73_RS21430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LPB73_RS21435	COG2076	Multidrug Resistance protein
LPB73_RS21445	COG1196	nuclear chromosome segregation
LPB73_RS21470	COG1704	LemA family
LPB73_RS21475	COG0501	Belongs to the peptidase M48B family
LPB73_RS21485	COG0604	alcohol dehydrogenase
LPB73_RS21490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LPB73_RS21515	COG0574	Belongs to the PEP-utilizing enzyme family
LPB73_RS21515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LPB73_RS21535	COG0751	glycine-tRNA ligase activity
LPB73_RS21540	COG0752	glycyl-tRNA synthetase alpha subunit
LPB73_RS21555	COG2813	Specifically methylates the guanine in position
LPB73_RS21565	COG0142	geranyltranstransferase activity
LPB73_RS21570	COG0604	alcohol dehydrogenase
LPB73_RS21590	COG0662	Cupin 2, conserved barrel domain protein
LPB73_RS21590	COG2207	Transcriptional regulator
LPB73_RS21595	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS21605	COG0154	amidase activity
LPB73_RS21610	COG0477	Major facilitator Superfamily
LPB73_RS21615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LPB73_RS21620	COG1618	nucleotide phosphatase activity, acting on free nucleotides
LPB73_RS21620	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LPB73_RS21625	COG2005	Transcriptional regulator
LPB73_RS21625	COG3585	molybdate ion transport
LPB73_RS21635	COG0655	NAD(P)H dehydrogenase (quinone) activity
LPB73_RS21640	COG1741	Belongs to the pirin family
LPB73_RS21645	COG0583	DNA-binding transcription factor activity
LPB73_RS21650	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS21660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS21685	COG1566	PFAM secretion protein HlyD family protein
LPB73_RS21715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPB73_RS21745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LPB73_RS21750	COG0385	Bile acid
LPB73_RS21755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LPB73_RS21755	COG2857	Cytochrome c1
LPB73_RS21760	COG0723	plastoquinol--plastocyanin reductase activity
LPB73_RS21765	COG4774	siderophore transport
LPB73_RS21775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LPB73_RS21790	COG0602	queuosine metabolic process
LPB73_RS21830	COG0617	tRNA 3'-terminal CCA addition
LPB73_RS21850	COG0714	Associated with various cellular activities
LPB73_RS21900	COG1051	belongs to the nudix hydrolase family
LPB73_RS21940	COG1902	pentaerythritol trinitrate reductase activity
LPB73_RS21955	COG0395	ABC-type sugar transport system, permease component
LPB73_RS21965	COG3842	ATPase activity
LPB73_RS21970	COG3842	ATPase activity
LPB73_RS21990	COG1607	acyl-coa hydrolase
LPB73_RS21995	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS21995	COG1024	Enoyl-CoA hydratase
LPB73_RS22005	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS22045	COG0443	Heat shock 70 kDa protein
LPB73_RS22050	COG2183	response to ionizing radiation
LPB73_RS22055	COG0154	amidase activity
LPB73_RS22060	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS22105	COG1253	flavin adenine dinucleotide binding
LPB73_RS22110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LPB73_RS22115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LPB73_RS22125	COG1309	transcriptional regulator
LPB73_RS22140	COG4974	Belongs to the 'phage' integrase family
LPB73_RS22155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB73_RS22180	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
LPB73_RS22190	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LPB73_RS22200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS22220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPB73_RS22225	COG0183	Belongs to the thiolase family
LPB73_RS22230	COG3485	protocatechuate 3,4-dioxygenase
LPB73_RS22235	COG3485	protocatechuate 3,4-dioxygenase
LPB73_RS22245	COG1566	PFAM secretion protein HlyD family protein
LPB73_RS22265	COG0735	belongs to the Fur family
LPB73_RS22275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LPB73_RS22300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LPB73_RS22305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LPB73_RS22320	COG3300	MHYT domain
LPB73_RS22320	COG5001	Diguanylate cyclase
LPB73_RS22350	COG1192	Involved in chromosome partitioning
LPB73_RS22390	COG2814	Major facilitator Superfamily
LPB73_RS22400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB73_RS22405	COG0235	Class ii aldolase
LPB73_RS22410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LPB73_RS22430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LPB73_RS22435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LPB73_RS22440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LPB73_RS22440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LPB73_RS22455	COG1473	amidohydrolase
LPB73_RS22480	COG0330	HflC and HflK could
LPB73_RS22500	COG1845	cytochrome c oxidase, subunit III
LPB73_RS22510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPB73_RS22515	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LPB73_RS22530	COG0251	oxidation-reduction process
LPB73_RS22535	COG3971	2-oxopent-4-enoate hydratase activity
LPB73_RS22540	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS22545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS22550	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS22560	COG2902	Dehydrogenase
LPB73_RS22570	COG3852	Histidine kinase
LPB73_RS22575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LPB73_RS22585	COG0706	membrane insertase activity
LPB73_RS22590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LPB73_RS22600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LPB73_RS22615	COG2171	N-acyltransferase activity
LPB73_RS22625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPB73_RS22630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPB73_RS22635	COG0101	tRNA pseudouridine synthase activity
LPB73_RS22640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPB73_RS22645	COG0242	peptide deformylase activity
LPB73_RS22660	COG2223	nitrite transmembrane transporter activity
LPB73_RS22670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPB73_RS22675	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LPB73_RS22680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPB73_RS22700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB73_RS22705	COG1522	sequence-specific DNA binding
LPB73_RS22710	COG2855	membrane
LPB73_RS22715	COG0583	DNA-binding transcription factor activity
LPB73_RS22720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPB73_RS22725	COG3577	Aspartyl protease
LPB73_RS22730	COG1643	Atp-dependent helicase
LPB73_RS22745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB73_RS22745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPB73_RS22755	COG1280	lysine exporter protein (LysE YggA)
LPB73_RS22760	COG0625	glutathione transferase activity
LPB73_RS22765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LPB73_RS22785	COG0058	SHG alpha-glucan phosphorylase activity
LPB73_RS22795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LPB73_RS22805	COG0745	RESPONSE REGULATOR receiver
LPB73_RS22810	COG2205	protein histidine kinase activity
LPB73_RS22815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPB73_RS22820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LPB73_RS22820	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LPB73_RS22825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LPB73_RS22835	COG0481	GTPase activity
LPB73_RS22855	COG0798	PFAM Bile acid sodium symporter
LPB73_RS22860	COG1393	Belongs to the ArsC family
LPB73_RS22865	COG0640	Transcriptional regulator
LPB73_RS22875	COG0583	DNA-binding transcription factor activity
LPB73_RS22885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS22895	COG5001	Diguanylate cyclase
LPB73_RS22900	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LPB73_RS22905	COG3585	molybdate ion transport
LPB73_RS22915	COG0725	ABC transporter, periplasmic molybdate-binding protein
LPB73_RS22920	COG4149	molybdate abc transporter
LPB73_RS22925	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LPB73_RS22935	COG1511	domain protein
LPB73_RS22935	COG3264	Mechanosensitive ion channel
LPB73_RS22940	COG1489	DNA binding
LPB73_RS22945	COG0024	Methionine aminopeptidase
LPB73_RS22950	COG2003	Belongs to the UPF0758 family
LPB73_RS22965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPB73_RS22970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS23000	COG0069	glutamate synthase activity
LPB73_RS23015	COG0285	dihydrofolate synthase activity
LPB73_RS23025	COG1301	dicarboxylic acid transport
LPB73_RS23030	COG2130	NADP-dependent
LPB73_RS23040	COG0784	Response regulator, receiver
LPB73_RS23040	COG4191	Histidine kinase
LPB73_RS23045	COG4191	Histidine kinase
LPB73_RS23045	COG0784	Response regulator, receiver
LPB73_RS23050	COG2199	diguanylate cyclase activity
LPB73_RS23050	COG2200	EAL domain
LPB73_RS23050	COG2202	Pas domain
LPB73_RS23055	COG2202	Pas domain
LPB73_RS23055	COG2200	EAL domain
LPB73_RS23055	COG2199	diguanylate cyclase activity
LPB73_RS23085	COG1228	amidohydrolase
LPB73_RS23090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LPB73_RS23105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPB73_RS23115	COG1132	(ABC) transporter
LPB73_RS23130	COG4774	siderophore transport
LPB73_RS23140	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS23145	COG0183	Belongs to the thiolase family
LPB73_RS23155	COG2176	DNA-directed DNA polymerase activity
LPB73_RS23170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LPB73_RS23175	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS23195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LPB73_RS23205	COG0156	8-amino-7-oxononanoate synthase activity
LPB73_RS23215	COG0784	Response regulator, receiver
LPB73_RS23215	COG2205	protein histidine kinase activity
LPB73_RS23215	COG2198	Histidine kinase
LPB73_RS23230	COG0432	Pfam Uncharacterised protein family UPF0047
LPB73_RS23260	COG0356	it plays a direct role in the translocation of protons across the membrane
LPB73_RS23275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPB73_RS23285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LPB73_RS23290	COG0612	Peptidase, M16
LPB73_RS23305	COG3346	SURF1 family
LPB73_RS23320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LPB73_RS23330	COG0109	protoheme IX farnesyltransferase activity
LPB73_RS23335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPB73_RS23340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LPB73_RS23365	COG1733	regulation of RNA biosynthetic process
LPB73_RS23375	COG0312	modulator of DNA gyrase
LPB73_RS23380	COG0681	Belongs to the peptidase S26 family
LPB73_RS23410	COG0625	glutathione transferase activity
LPB73_RS23415	COG1024	Enoyl-CoA hydratase
LPB73_RS23415	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS23420	COG0183	Belongs to the thiolase family
LPB73_RS23425	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS23450	COG0730	response to heat
LPB73_RS23475	COG0583	DNA-binding transcription factor activity
LPB73_RS23490	COG1201	RNA secondary structure unwinding
LPB73_RS23510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LPB73_RS23525	COG1793	dna ligase
LPB73_RS23535	COG0534	Mate efflux family protein
LPB73_RS23540	COG0167	dihydroorotate dehydrogenase activity
LPB73_RS23560	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LPB73_RS23575	COG1999	signal sequence binding
LPB73_RS23595	COG0598	Magnesium transport protein CorA
LPB73_RS23640	COG2721	sulfolactate sulfo-lyase activity
LPB73_RS23650	COG0667	Aldo Keto reductase
LPB73_RS23665	COG0717	Belongs to the dCTP deaminase family
LPB73_RS23700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LPB73_RS23705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LPB73_RS23715	COG0745	RESPONSE REGULATOR receiver
LPB73_RS23720	COG0704	Plays a role in the regulation of phosphate uptake
LPB73_RS23725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LPB73_RS23730	COG0581	inorganic phosphate transmembrane transporter activity
LPB73_RS23735	COG0573	inorganic phosphate transmembrane transporter activity
LPB73_RS23740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LPB73_RS23745	COG5002	protein histidine kinase activity
LPB73_RS23770	COG0517	IMP dehydrogenase activity
LPB73_RS23770	COG0617	tRNA 3'-terminal CCA addition
LPB73_RS23770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LPB73_RS23780	COG1335	isochorismatase
LPB73_RS23800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LPB73_RS23825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS23835	COG1522	sequence-specific DNA binding
LPB73_RS23845	COG3813	Protein conserved in bacteria
LPB73_RS23850	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LPB73_RS23925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LPB73_RS23945	COG1132	(ABC) transporter
LPB73_RS23950	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS23955	COG0025	NhaP-type Na H and K H
LPB73_RS24015	COG0243	molybdopterin cofactor binding
LPB73_RS24020	COG1902	pentaerythritol trinitrate reductase activity
LPB73_RS24030	COG0243	molybdopterin cofactor binding
LPB73_RS24030	COG0243	molybdopterin cofactor binding
LPB73_RS24035	COG0243	molybdopterin cofactor binding
LPB73_RS24050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS24055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPB73_RS24060	COG1522	sequence-specific DNA binding
LPB73_RS24065	COG0488	(ABC) transporter
LPB73_RS24080	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS24095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS24130	COG4191	Histidine kinase
LPB73_RS24135	COG4566	intracellular signal transduction
LPB73_RS24140	COG4566	intracellular signal transduction
LPB73_RS24175	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS24205	COG1309	transcriptional regulator
LPB73_RS24255	COG2894	cell division
LPB73_RS24270	COG0438	transferase activity, transferring glycosyl groups
LPB73_RS24280	COG1596	polysaccharide export
LPB73_RS24290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB73_RS24295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LPB73_RS24300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LPB73_RS24305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LPB73_RS24310	COG2197	response regulator
LPB73_RS24315	COG2197	response regulator
LPB73_RS24345	COG1749	Flagellar hook protein flgE
LPB73_RS24350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LPB73_RS24365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LPB73_RS24370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LPB73_RS24375	COG1595	DNA-templated transcription, initiation
LPB73_RS24405	COG0411	ABC transporter
LPB73_RS24435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPB73_RS24440	COG1760	l-serine dehydratase
LPB73_RS24450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LPB73_RS24450	COG0446	pyridine nucleotide-disulphide oxidoreductase
LPB73_RS24460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LPB73_RS24495	COG0583	DNA-binding transcription factor activity
LPB73_RS24500	COG4948	Mandelate Racemase Muconate Lactonizing
LPB73_RS24505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LPB73_RS24510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LPB73_RS24525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPB73_RS24530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LPB73_RS24540	COG2814	Major facilitator Superfamily
LPB73_RS24570	COG4221	oxidoreductase activity
LPB73_RS24585	COG1872	DUF167
LPB73_RS24590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPB73_RS24595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LPB73_RS24600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LPB73_RS24605	COG1247	-acetyltransferase
LPB73_RS24615	COG3011	Protein conserved in bacteria
LPB73_RS24625	COG0625	glutathione transferase activity
LPB73_RS24630	COG1217	gtp-binding protein TYPA
LPB73_RS24640	COG4774	siderophore transport
LPB73_RS24655	COG2154	pterin-4-alpha-carbinolamine dehydratase
LPB73_RS24670	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS24680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LPB73_RS24700	COG0137	argininosuccinate synthase activity
LPB73_RS24710	COG1309	transcriptional regulator
LPB73_RS24715	COG1785	Belongs to the alkaline phosphatase family
LPB73_RS24740	COG4178	(ABC) transporter
LPB73_RS24750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS24755	COG1116	anion transmembrane transporter activity
LPB73_RS24760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS24785	COG0730	response to heat
LPB73_RS24795	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS24800	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LPB73_RS24805	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LPB73_RS24810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LPB73_RS24815	COG0477	Major facilitator Superfamily
LPB73_RS24820	COG0473	3-isopropylmalate dehydrogenase activity
LPB73_RS24835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPB73_RS24840	COG0288	reversible hydration of carbon dioxide
LPB73_RS24845	COG2301	Belongs to the HpcH HpaI aldolase family
LPB73_RS24855	COG0066	3-isopropylmalate dehydratase activity
LPB73_RS24885	COG3214	Protein conserved in bacteria
LPB73_RS24895	COG0335	large ribosomal subunit rRNA binding
LPB73_RS24905	COG0702	epimerase
LPB73_RS24915	COG0228	four-way junction DNA binding
LPB73_RS24920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPB73_RS24930	COG2910	NAD(P)H-binding
LPB73_RS24950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LPB73_RS24955	COG0564	pseudouridine synthase activity
LPB73_RS24960	COG0552	protein localization to endoplasmic reticulum
LPB73_RS24965	COG2917	probably involved in intracellular septation
LPB73_RS24975	COG1185	polyribonucleotide nucleotidyltransferase activity
LPB73_RS24980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LPB73_RS24985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPB73_RS24990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LPB73_RS24995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LPB73_RS25010	COG0779	Required for maturation of 30S ribosomal subunits
LPB73_RS25025	COG0667	Aldo Keto reductase
LPB73_RS25030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LPB73_RS25045	COG1487	ribonuclease activity
LPB73_RS25055	COG2226	methyltransferase
LPB73_RS25060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS25065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LPB73_RS25070	COG2226	methyltransferase
LPB73_RS25075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LPB73_RS25080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPB73_RS25085	COG0756	dUTP diphosphatase activity
LPB73_RS25090	COG2205	protein histidine kinase activity
LPB73_RS25095	COG3178	'Phosphotransferase
LPB73_RS25105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LPB73_RS25115	COG1074	ATP-dependent DNA helicase activity
LPB73_RS25130	COG0285	dihydrofolate synthase activity
LPB73_RS25135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LPB73_RS25140	COG0159	tryptophan synthase activity
LPB73_RS25145	COG0133	tryptophan synthase activity
LPB73_RS25150	COG0135	phosphoribosylanthranilate isomerase activity
LPB73_RS25160	COG0776	regulation of translation
LPB73_RS25165	COG0616	signal peptide processing
LPB73_RS25170	COG0539	negative regulation of cytoplasmic translation
LPB73_RS25175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LPB73_RS25195	COG1846	Transcriptional regulator
LPB73_RS25200	COG1764	response to oxidative stress
LPB73_RS25205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS25210	COG1653	transport
LPB73_RS25215	COG1175	transmembrane transport
LPB73_RS25220	COG0395	ABC-type sugar transport system, permease component
LPB73_RS25225	COG3842	ATPase activity
LPB73_RS25230	COG0071	Belongs to the small heat shock protein (HSP20) family
LPB73_RS25250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LPB73_RS25255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LPB73_RS25260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LPB73_RS25265	COG1137	ATPase activity
LPB73_RS25270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LPB73_RS25295	COG2368	4-hydroxyphenylacetate
LPB73_RS25300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS25315	COG2205	protein histidine kinase activity
LPB73_RS25320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LPB73_RS25325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LPB73_RS25330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LPB73_RS25350	COG3734	2-keto-3-deoxy-galactonokinase
LPB73_RS25355	COG0800	Aldolase
LPB73_RS25370	COG1968	undecaprenyl-diphosphatase activity
LPB73_RS25380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LPB73_RS25395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LPB73_RS25405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LPB73_RS25410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LPB73_RS25415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LPB73_RS25420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPB73_RS25420	COG0072	phenylalanine-tRNA ligase activity
LPB73_RS25430	COG1234	tRNA 3'-trailer cleavage
LPB73_RS25450	COG1175	transmembrane transport
LPB73_RS25465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPB73_RS25475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPB73_RS25480	COG2814	Major facilitator Superfamily
LPB73_RS25485	COG1012	belongs to the aldehyde dehydrogenase family
LPB73_RS25490	COG1802	Transcriptional regulator
LPB73_RS25500	COG0588	phosphoglycerate mutase activity
LPB73_RS25505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LPB73_RS25515	COG0284	orotidine-5'-phosphate decarboxylase activity
LPB73_RS25520	COG0431	NADPH-dependent FMN reductase
LPB73_RS25525	COG3963	phosphatidate phosphatase activity
LPB73_RS25530	COG0484	heat shock protein binding
LPB73_RS25535	COG0443	Heat shock 70 kDa protein
LPB73_RS25545	COG1335	isochorismatase
LPB73_RS25550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPB73_RS25555	COG1420	regulation of RNA biosynthetic process
LPB73_RS25560	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LPB73_RS25565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LPB73_RS25570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LPB73_RS25580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPB73_RS25585	COG0792	nuclease activity
LPB73_RS25590	COG0189	ligase activity
LPB73_RS25600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LPB73_RS25605	COG5001	Diguanylate cyclase
LPB73_RS25605	COG3447	MASE1 domain protein
LPB73_RS25605	COG5002	protein histidine kinase activity
LPB73_RS25630	COG1072	(Pantothenic acid kinase))
LPB73_RS25635	COG0140	phosphoribosyl-ATP diphosphatase activity
LPB73_RS25645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LPB73_RS25650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LPB73_RS25660	COG0131	Imidazoleglycerol-phosphate dehydratase
LPB73_RS25665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LPB73_RS25675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LPB73_RS25685	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LPB73_RS25705	COG0237	dephospho-CoA kinase activity
LPB73_RS25710	COG0424	maF-like protein
LPB73_RS25715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LPB73_RS25720	COG1981	membrane
LPB73_RS25725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LPB73_RS25730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPB73_RS25735	COG0445	tRNA wobble uridine modification
LPB73_RS25750	COG0357	Ribosomal RNA small subunit methyltransferase G
LPB73_RS25775	COG0495	leucyl-tRNA aminoacylation
LPB73_RS25785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LPB73_RS25795	COG0745	RESPONSE REGULATOR receiver
LPB73_RS25810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LPB73_RS25815	COG1674	ftsk spoiiie
LPB73_RS25820	COG0436	Aminotransferase
LPB73_RS25825	COG0004	ammonium transporteR
LPB73_RS25830	COG0347	Belongs to the P(II) protein family
LPB73_RS25835	COG0347	Belongs to the P(II) protein family
LPB73_RS25840	COG1946	Acyl-CoA thioesterase
LPB73_RS25845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LPB73_RS25855	COG0625	glutathione transferase activity
LPB73_RS25870	COG2835	tetraacyldisaccharide 4'-kinase activity
LPB73_RS25880	COG3118	belongs to the thioredoxin family
LPB73_RS25905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPB73_RS25920	COG0534	Mate efflux family protein
LPB73_RS25940	COG2814	Major facilitator Superfamily
LPB73_RS25945	COG0405	Gamma-glutamyltransferase
LPB73_RS25955	COG0138	bifunctional purine biosynthesis protein purh
LPB73_RS25980	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS25990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LPB73_RS26000	COG2264	protein methyltransferase activity
LPB73_RS26010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LPB73_RS26015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LPB73_RS26040	COG1116	anion transmembrane transporter activity
LPB73_RS26045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS26050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS26055	COG0251	oxidation-reduction process
LPB73_RS26060	COG1335	isochorismatase
LPB73_RS26070	COG0583	DNA-binding transcription factor activity
LPB73_RS26075	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LPB73_RS26080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPB73_RS26085	COG0799	negative regulation of ribosome biogenesis
LPB73_RS26090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPB73_RS26100	COG0793	Belongs to the peptidase S41A family
LPB73_RS26110	COG1051	belongs to the nudix hydrolase family
LPB73_RS26115	COG0494	nUDIX hydrolase
LPB73_RS26120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LPB73_RS26125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPB73_RS26130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPB73_RS26135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPB73_RS26145	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LPB73_RS26160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LPB73_RS26170	COG2267	carboxylic ester hydrolase activity
LPB73_RS26180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LPB73_RS26185	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS26195	COG0508	dehydrogenase complex catalyzes the overall conversion of
LPB73_RS26205	COG1309	transcriptional regulator
LPB73_RS26225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LPB73_RS26230	COG0045	succinate-CoA ligase (ADP-forming) activity
LPB73_RS26240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LPB73_RS26245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LPB73_RS26255	COG4181	ATPase activity
LPB73_RS26260	COG0577	efflux transmembrane transporter activity
LPB73_RS26260	COG1136	(ABC) transporter
LPB73_RS26265	COG0670	Belongs to the BI1 family
LPB73_RS26285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LPB73_RS26290	COG4133	protoheme IX ABC transporter activity
LPB73_RS26295	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LPB73_RS26300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LPB73_RS26310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB73_RS26325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LPB73_RS26335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LPB73_RS26345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LPB73_RS26370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LPB73_RS26375	COG1396	sequence-specific DNA binding
LPB73_RS26380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LPB73_RS26385	COG1253	flavin adenine dinucleotide binding
LPB73_RS26390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LPB73_RS26400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LPB73_RS26405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LPB73_RS26445	COG0180	Tryptophanyl-tRNA synthetase
LPB73_RS26455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPB73_RS26505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LPB73_RS26510	COG1741	Belongs to the pirin family
LPB73_RS26520	COG0583	DNA-binding transcription factor activity
LPB73_RS26565	COG3278	Belongs to the heme-copper respiratory oxidase family
LPB73_RS26580	COG2010	Cytochrome c
LPB73_RS26605	COG0477	Major facilitator Superfamily
LPB73_RS26610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LPB73_RS26615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LPB73_RS26620	COG1845	cytochrome c oxidase, subunit III
LPB73_RS26625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LPB73_RS26630	COG3346	SURF1 family
LPB73_RS26640	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LPB73_RS26645	COG0402	S-adenosylhomocysteine deaminase activity
LPB73_RS26660	COG1116	anion transmembrane transporter activity
LPB73_RS26670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LPB73_RS26680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LPB73_RS26685	COG1024	Enoyl-CoA hydratase
LPB73_RS26710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPB73_RS26720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPB73_RS26725	COG0268	Binds directly to 16S ribosomal RNA
LPB73_RS26735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPB73_RS26750	COG0412	Dienelactone hydrolase
LPB73_RS26775	COG3181	Tripartite tricarboxylate transporter family receptor
LPB73_RS26795	COG2986	histidine ammonia-lyase
LPB73_RS26800	COG1157	protein secretion by the type III secretion system
LPB73_RS26805	COG4786	Flagellar basal body rod
LPB73_RS26815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LPB73_RS26830	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPB73_RS26835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LPB73_RS26840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPB73_RS26845	COG1815	bacterial-type flagellum-dependent cell motility
LPB73_RS26850	COG1558	bacterial-type flagellum-dependent cell motility
LPB73_RS26855	COG1677	Flagellar hook-basal body complex protein FliE
LPB73_RS26860	COG4786	Flagellar basal body rod
LPB73_RS26870	COG1706	bacterial-type flagellum-dependent cell motility
LPB73_RS26880	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LPB73_RS26890	COG1338	Plays a role in the flagellum-specific transport system
LPB73_RS26900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LPB73_RS26930	COG0741	lytic transglycosylase activity
LPB73_RS26935	COG1749	Flagellar hook protein flgE
LPB73_RS26955	COG5443	negative regulation of bacterial-type flagellum assembly
LPB73_RS26970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LPB73_RS27025	COG2226	methyltransferase
LPB73_RS27035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LPB73_RS27060	COG5001	Diguanylate cyclase
LPB73_RS27065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS27070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LPB73_RS27075	COG1116	anion transmembrane transporter activity
LPB73_RS27080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS27090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS27095	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
LPB73_RS27115	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS27145	COG0501	Belongs to the peptidase M48B family
LPB73_RS27220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LPB73_RS27235	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LPB73_RS27245	COG2514	catechol 2,3-dioxygenase activity
LPB73_RS27255	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS27260	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS27265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB73_RS27280	COG1294	oxidase, subunit
LPB73_RS27285	COG1271	oxidase subunit
LPB73_RS27300	COG3437	response regulator, receiver
LPB73_RS27300	COG0784	Response regulator, receiver
LPB73_RS27305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LPB73_RS27305	COG4191	Histidine kinase
LPB73_RS27310	COG1653	transport
LPB73_RS27315	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LPB73_RS27320	COG0848	biopolymer transport protein
LPB73_RS27340	COG0601	transmembrane transport
LPB73_RS27345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LPB73_RS27350	COG4172	Belongs to the ABC transporter superfamily
LPB73_RS27370	COG2186	Transcriptional regulator
LPB73_RS27375	COG2271	Major facilitator Superfamily
LPB73_RS27380	COG1877	trehalose-phosphatase activity
LPB73_RS27385	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LPB73_RS27405	COG2084	Dehydrogenase
LPB73_RS27410	COG2188	Transcriptional regulator
LPB73_RS27425	COG1172	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS27440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LPB73_RS27480	COG0628	permease
LPB73_RS27490	COG2197	response regulator
LPB73_RS27495	COG4585	Histidine kinase
LPB73_RS27500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LPB73_RS27515	COG2235	arginine
LPB73_RS27540	COG1320	monovalent cation:proton antiporter activity
LPB73_RS27545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LPB73_RS27545	COG2111	Na H antiporter
LPB73_RS27555	COG0651	ATP synthesis coupled electron transport
LPB73_RS27560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LPB73_RS27560	COG2111	Na H antiporter
LPB73_RS27615	COG0514	ATP-dependent DNA helicase (RecQ)
LPB73_RS27630	COG3246	L-lysine catabolic process to acetate
LPB73_RS27635	COG0129	dihydroxy-acid dehydratase activity
LPB73_RS27640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LPB73_RS27650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LPB73_RS27665	COG0840	transmembrane signaling receptor activity
LPB73_RS27685	COG0326	Molecular chaperone. Has ATPase activity
LPB73_RS27715	COG2271	Major facilitator Superfamily
LPB73_RS27720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LPB73_RS27725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LPB73_RS27730	COG3278	Belongs to the heme-copper respiratory oxidase family
LPB73_RS27745	COG2010	Cytochrome c
LPB73_RS27775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LPB73_RS27790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LPB73_RS27815	COG0559	Belongs to the binding-protein-dependent transport system permease family
LPB73_RS27865	COG0583	DNA-binding transcription factor activity
LPB73_RS27880	COG3383	formate dehydrogenase (NAD+) activity
LPB73_RS27885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LPB73_RS27905	COG3034	peptidoglycan biosynthetic process
LPB73_RS27910	COG1285	pathogenesis
LPB73_RS27915	COG0653	protein targeting
LPB73_RS27920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LPB73_RS27925	COG4221	oxidoreductase activity
LPB73_RS27930	COG4977	sequence-specific DNA binding
LPB73_RS27935	COG0825	malonyl-CoA metabolic process
LPB73_RS27965	COG5001	Diguanylate cyclase
LPB73_RS27970	COG5001	Diguanylate cyclase
LPB73_RS27970	COG4251	negative regulation of phosphorylation
LPB73_RS27970	COG3706	GGDEF domain
LPB73_RS27970	COG2203	Gaf domain
LPB73_RS27975	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS27980	COG2207	Transcriptional regulator
LPB73_RS28015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LPB73_RS28055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LPB73_RS28080	COG1024	Enoyl-CoA hydratase
LPB73_RS28095	COG1024	Enoyl-CoA hydratase
LPB73_RS28100	COG1960	acyl-CoA dehydrogenase activity
LPB73_RS28125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LPB73_RS28160	COG5001	Diguanylate cyclase
LPB73_RS28225	COG0154	amidase activity
LPB73_RS28235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LPB73_RS28285	COG2890	protein-(glutamine-N5) methyltransferase activity
LPB73_RS28290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPB73_RS28300	COG0527	aspartate kinase activity
LPB73_RS28310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LPB73_RS28370	COG1764	response to oxidative stress
LPB73_RS28375	COG1846	Transcriptional regulator
LPB73_RS28390	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS28405	COG2719	SpoVR family
LPB73_RS28410	COG2718	Belongs to the UPF0229 family
LPB73_RS28415	COG2766	serine protein kinase
LPB73_RS28430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LPB73_RS28435	COG1040	competence protein
LPB73_RS28445	COG0494	nUDIX hydrolase
LPB73_RS28455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LPB73_RS28490	COG2358	TRAP transporter, solute receptor (TAXI family
LPB73_RS28505	COG2358	TRAP transporter, solute receptor (TAXI family
LPB73_RS28530	COG3047	cAMP biosynthetic process
LPB73_RS28535	COG2824	Alkylphosphonate utilization operon protein PhnA
LPB73_RS28555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LPB73_RS28560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LPB73_RS28580	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS28585	COG1686	Belongs to the peptidase S11 family
LPB73_RS28590	COG1132	(ABC) transporter
LPB73_RS28605	COG0140	phosphoribosyl-ATP diphosphatase activity
LPB73_RS28610	COG1238	metal cluster binding
LPB73_RS28640	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LPB73_RS28645	COG4191	Histidine kinase
LPB73_RS28645	COG0784	Response regulator, receiver
LPB73_RS28660	COG0306	phosphate transporter
LPB73_RS28670	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS28680	COG0598	Magnesium transport protein CorA
LPB73_RS28690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LPB73_RS28705	COG2814	Major facilitator Superfamily
LPB73_RS28750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LPB73_RS28750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LPB73_RS28765	COG1733	regulation of RNA biosynthetic process
LPB73_RS28770	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS28780	COG0038	chloride channel
LPB73_RS28800	COG0179	Fumarylacetoacetate (FAA) hydrolase
LPB73_RS28815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LPB73_RS28825	COG4772	TonB-dependent receptor
LPB73_RS28835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LPB73_RS28840	COG1388	LysM domain
LPB73_RS28840	COG1376	ErfK ybiS ycfS ynhG family protein
LPB73_RS28850	COG1028	Short-chain dehydrogenase reductase Sdr
LPB73_RS28855	COG0583	DNA-binding transcription factor activity
LPB73_RS28860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPB73_RS28865	COG0784	Response regulator, receiver
LPB73_RS28865	COG2198	Histidine kinase
LPB73_RS28865	COG5002	protein histidine kinase activity
LPB73_RS28885	COG2086	electron transfer activity
LPB73_RS28890	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LPB73_RS28895	COG1250	3-hydroxyacyl-CoA dehydrogenase
LPB73_RS28900	COG1942	4-Oxalocrotonate Tautomerase
LPB73_RS28905	COG0583	DNA-binding transcription factor activity
LPB73_RS28930	COG5507	3-demethylubiquinone-9 3-methyltransferase
LPB73_RS28935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LPB73_RS28940	COG0165	Argininosuccinate lyase
LPB73_RS28950	COG0019	diaminopimelate decarboxylase activity
LPB73_RS28960	COG2204	response regulator
LPB73_RS28970	COG2884	Cell division ATP-binding protein ftsE
LPB73_RS29000	COG0287	Prephenate dehydrogenase
LPB73_RS29005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LPB73_RS29015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS29020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LPB73_RS29020	COG2813	Specifically methylates the guanine in position
LPB73_RS29035	COG0542	response to heat
LPB73_RS29040	COG0702	epimerase
LPB73_RS29045	COG0739	heme binding
LPB73_RS29095	COG0318	PFAM AMP-dependent synthetase and ligase
LPB73_RS29125	COG0546	phosphoglycolate phosphatase activity