locus-tag	class	description
CA604_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CA604_RS00025	COG4608	Belongs to the ABC transporter superfamily
CA604_RS00030	COG0601	transmembrane transport
CA604_RS00035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA604_RS00040	COG0444	Belongs to the ABC transporter superfamily
CA604_RS00045	COG4166	transmembrane transport
CA604_RS00055	COG1074	ATP-dependent DNA helicase activity
CA604_RS00070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CA604_RS00070	COG0551	DNA topoisomerase type I activity
CA604_RS00075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA604_RS00085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA604_RS00090	COG2922	Belongs to the Smg family
CA604_RS00110	COG0018	arginyl-trna synthetase
CA604_RS00120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CA604_RS00150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CA604_RS00170	COG1160	GTP binding
CA604_RS00190	COG2431	L-lysine efflux transmembrane transporter activity
CA604_RS00205	COG4160	amino acid transport
CA604_RS00210	COG4598	ABC transporter
CA604_RS00215	COG0730	response to heat
CA604_RS00230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CA604_RS00240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CA604_RS00250	COG1994	Peptidase M50
CA604_RS00255	COG0859	PFAM glycosyl transferase family 9
CA604_RS00270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CA604_RS00280	COG2945	thiolester hydrolase activity
CA604_RS00285	COG1686	Belongs to the peptidase S11 family
CA604_RS00295	COG2921	Belongs to the UPF0250 family
CA604_RS00315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CA604_RS00320	COG1088	dTDP-glucose 4,6-dehydratase activity
CA604_RS00325	COG2814	Major facilitator Superfamily
CA604_RS00350	COG0513	Belongs to the DEAD box helicase family
CA604_RS00355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CA604_RS00360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA604_RS00360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA604_RS00375	COG2204	response regulator
CA604_RS00380	COG0569	domain protein
CA604_RS00390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CA604_RS00395	COG1040	competence protein
CA604_RS00400	COG2226	methyltransferase
CA604_RS00720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CA604_RS00725	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CA604_RS00730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CA604_RS00740	COG0588	phosphoglycerate mutase activity
CA604_RS00745	COG4942	peptidase
CA604_RS00750	COG0793	Belongs to the peptidase S41A family
CA604_RS00755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CA604_RS00760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CA604_RS00775	COG0356	it plays a direct role in the translocation of protons across the membrane
CA604_RS00790	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CA604_RS00795	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CA604_RS00800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CA604_RS00805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CA604_RS00810	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CA604_RS00830	COG1131	(ABC) transporter
CA604_RS00860	COG0523	cobalamin synthesis protein
CA604_RS00865	COG0735	belongs to the Fur family
CA604_RS00870	COG1121	(ABC) transporter
CA604_RS00875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CA604_RS00885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CA604_RS00895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CA604_RS00900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA604_RS00910	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CA604_RS00915	COG1077	Cell shape determining protein MreB Mrl
CA604_RS00930	COG0768	penicillin binding
CA604_RS00935	COG0772	Belongs to the SEDS family
CA604_RS00940	COG2177	Part of the ABC transporter FtsEX involved in
CA604_RS00945	COG2884	Cell division ATP-binding protein ftsE
CA604_RS00950	COG4597	amino acid ABC transporter
CA604_RS00955	COG0765	amino acid transport
CA604_RS00960	COG1126	abc transporter atp-binding protein
CA604_RS00975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CA604_RS01000	COG0237	dephospho-CoA kinase activity
CA604_RS01005	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CA604_RS01010	COG1045	serine acetyltransferase
CA604_RS01025	COG0142	geranyltranstransferase activity
CA604_RS01030	COG0129	dihydroxy-acid dehydratase activity
CA604_RS01035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CA604_RS01050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CA604_RS01055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CA604_RS01075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CA604_RS01080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CA604_RS01085	COG0179	Fumarylacetoacetate (FAA) hydrolase
CA604_RS01095	COG0826	peptidase U32
CA604_RS01110	COG1518	maintenance of DNA repeat elements
CA604_RS01145	COG0601	transmembrane transport
CA604_RS01150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA604_RS01160	COG4608	Belongs to the ABC transporter superfamily
CA604_RS01180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CA604_RS01190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CA604_RS01195	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CA604_RS01200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CA604_RS01210	COG2823	Periplasmic or secreted lipoprotein
CA604_RS01215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CA604_RS01220	COG0792	nuclease activity
CA604_RS01235	COG1660	Displays ATPase and GTPase activities
CA604_RS01240	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CA604_RS01250	COG1137	ATPase activity
CA604_RS01265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CA604_RS01275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CA604_RS01280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CA604_RS01290	COG0745	RESPONSE REGULATOR receiver
CA604_RS01295	COG2226	methyltransferase
CA604_RS01305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CA604_RS01310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CA604_RS01320	COG0351	phosphomethylpyrimidine kinase
CA604_RS01325	COG2326	polyphosphate kinase activity
CA604_RS01345	COG0720	synthase
CA604_RS01350	COG0602	queuosine metabolic process
CA604_RS01380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CA604_RS01385	COG2890	protein-(glutamine-N5) methyltransferase activity
CA604_RS01390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CA604_RS01405	COG0471	metal ion transport
CA604_RS01440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CA604_RS01440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CA604_RS01450	COG2830	Protein of unknown function (DUF452)
CA604_RS01455	COG0500	methyltransferase
CA604_RS01460	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CA604_RS01465	COG0584	glycerophosphoryl diester phosphodiesterase
CA604_RS01470	COG1063	alcohol dehydrogenase
CA604_RS01485	COG2119	membrane
CA604_RS01495	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CA604_RS01495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CA604_RS01505	COG1629	transport
CA604_RS01505	COG4771	TonB-dependent receptor
CA604_RS01510	COG0037	tRNA processing
CA604_RS01520	COG0492	ferredoxin-NADP+ reductase activity
CA604_RS01525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CA604_RS01535	COG4215	(ABC) transporter
CA604_RS01550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CA604_RS01555	COG0589	response to stress
CA604_RS01565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CA604_RS01610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA604_RS01615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CA604_RS01620	COG1652	LysM domain
CA604_RS01625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CA604_RS01655	COG0717	Belongs to the dCTP deaminase family
CA604_RS01660	COG2081	HI0933 family
CA604_RS01670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CA604_RS01675	COG0509	glycine decarboxylation via glycine cleavage system
CA604_RS01680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA604_RS01680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CA604_RS01685	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CA604_RS01690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CA604_RS01695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CA604_RS01705	COG0277	FAD linked oxidase domain protein
CA604_RS01710	COG0457	Tetratricopeptide repeat
CA604_RS01715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CA604_RS01720	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CA604_RS01730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CA604_RS01735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CA604_RS01780	COG0012	GTP binding
CA604_RS01785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CA604_RS01790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CA604_RS01795	COG0742	ribosomal rna small subunit methyltransferase
CA604_RS01820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CA604_RS01825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA604_RS01830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CA604_RS01835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CA604_RS01840	COG1546	Belongs to the CinA family
CA604_RS01845	COG0284	orotidine-5'-phosphate decarboxylase activity
CA604_RS01850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CA604_RS01860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CA604_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CA604_RS01895	COG0823	Involved in the tonB-independent uptake of proteins
CA604_RS01910	COG0811	peptide transport
CA604_RS01915	COG0824	Thioesterase
CA604_RS01920	COG0442	prolyl-tRNA aminoacylation
CA604_RS01925	COG0494	nUDIX hydrolase
CA604_RS01955	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CA604_RS01955	COG0506	proline dehydrogenase activity
CA604_RS01955	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CA604_RS01960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CA604_RS01965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CA604_RS02010	COG0733	neurotransmitter:sodium symporter activity
CA604_RS02025	COG0438	transferase activity, transferring glycosyl groups
CA604_RS02060	COG0367	asparagine synthase
CA604_RS02075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CA604_RS02115	COG0418	dihydroorotase activity
CA604_RS02120	COG4122	O-methyltransferase activity
CA604_RS02130	COG0747	negative chemotaxis
CA604_RS02135	COG0747	negative chemotaxis
CA604_RS02140	COG0601	transmembrane transport
CA604_RS02145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA604_RS02150	COG0444	Belongs to the ABC transporter superfamily
CA604_RS02155	COG4608	Belongs to the ABC transporter superfamily
CA604_RS02160	COG0604	alcohol dehydrogenase
CA604_RS02160	COG3321	synthase
CA604_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
CA604_RS02170	COG0149	triose-phosphate isomerase activity
CA604_RS02175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CA604_RS02200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CA604_RS02205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA604_RS02210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA604_RS02215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA604_RS02220	COG0649	NAD binding
CA604_RS02225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CA604_RS02235	COG1034	ATP synthesis coupled electron transport
CA604_RS02240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CA604_RS02245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CA604_RS02255	COG0713	ATP synthesis coupled electron transport
CA604_RS02270	COG1007	ATP synthesis coupled electron transport
CA604_RS02280	COG0560	Phosphoserine phosphatase
CA604_RS02285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CA604_RS02290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CA604_RS02290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CA604_RS02295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CA604_RS02300	COG0450	alkyl hydroperoxide reductase
CA604_RS02305	COG2205	protein histidine kinase activity
CA604_RS02315	COG1214	PFAM Peptidase M22, glycoprotease
CA604_RS02330	COG1196	nuclear chromosome segregation
CA604_RS02340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CA604_RS02345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA604_RS02355	COG2917	probably involved in intracellular septation
CA604_RS02385	COG0410	ABC transporter
CA604_RS02390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CA604_RS02395	COG2878	Part of a membrane complex involved in electron transport
CA604_RS02400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA604_RS02410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CA604_RS02415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA604_RS02420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CA604_RS02425	COG1530	ribonuclease E activity
CA604_RS02430	COG0564	pseudouridine synthase activity
CA604_RS02445	COG0424	maF-like protein
CA604_RS02455	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CA604_RS02460	COG0416	fatty acid biosynthetic process
CA604_RS02465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CA604_RS02470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CA604_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
CA604_RS02480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CA604_RS02485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CA604_RS02495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA604_RS02505	COG0681	Belongs to the peptidase S26 family
CA604_RS02510	COG0571	ribonuclease III activity
CA604_RS02515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CA604_RS02520	COG1381	Involved in DNA repair and RecF pathway recombination
CA604_RS02525	COG0670	Belongs to the BI1 family
CA604_RS02535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CA604_RS02545	COG0583	DNA-binding transcription factor activity
CA604_RS02550	COG3226	Transcriptional regulator
CA604_RS02560	COG0791	NLP P60 protein
CA604_RS02580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CA604_RS02585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CA604_RS02600	COG0254	rRNA binding
CA604_RS02605	COG2003	Belongs to the UPF0758 family
CA604_RS02610	COG1047	Peptidyl-prolyl cis-trans
CA604_RS02615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CA604_RS02625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CA604_RS02630	COG0799	negative regulation of ribosome biogenesis
CA604_RS02635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CA604_RS02645	COG0217	transcriptional regulatory protein
CA604_RS02650	COG0433	COG0433 Predicted ATPase
CA604_RS02655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CA604_RS02660	COG0308	aminopeptidase N
CA604_RS02665	COG0312	modulator of DNA gyrase
CA604_RS02670	COG0482	sulfurtransferase activity
CA604_RS02680	COG3909	cytochrome
CA604_RS02700	COG0069	glutamate synthase activity
CA604_RS02710	COG4290	ribonuclease
CA604_RS02725	COG0488	(ABC) transporter
CA604_RS02730	COG2951	lytic endotransglycosylase activity
CA604_RS02735	COG0793	Belongs to the peptidase S41A family
CA604_RS02770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CA604_RS02775	COG1605	Chorismate mutase
CA604_RS02775	COG0077	Prephenate dehydratase
CA604_RS02780	COG0287	Prephenate dehydrogenase
CA604_RS02785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CA604_RS02795	COG0776	regulation of translation
CA604_RS02805	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CA604_RS02810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CA604_RS02815	COG1555	photosystem II stabilization
CA604_RS02815	COG1596	polysaccharide export
CA604_RS02820	COG2217	Heavy metal translocating P-type atpase
CA604_RS02820	COG2608	mercury ion transmembrane transporter activity
CA604_RS02830	COG3278	Belongs to the heme-copper respiratory oxidase family
CA604_RS02860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CA604_RS02870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CA604_RS02880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CA604_RS02895	COG1981	membrane
CA604_RS02910	COG0495	leucyl-tRNA aminoacylation
CA604_RS02915	COG2195	Cleaves the N-terminal amino acid of tripeptides
CA604_RS02920	COG2850	peptidyl-arginine hydroxylation
CA604_RS02925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CA604_RS02930	COG0668	transmembrane transport
CA604_RS02940	COG0483	inositol monophosphate 1-phosphatase activity
CA604_RS02945	COG1968	undecaprenyl-diphosphatase activity
CA604_RS02965	COG0215	cysteine-tRNA ligase activity
CA604_RS02970	COG0825	malonyl-CoA metabolic process
CA604_RS02990	COG2358	TRAP transporter, solute receptor (TAXI family
CA604_RS03010	COG4178	(ABC) transporter
CA604_RS03030	COG1666	GTP binding
CA604_RS03035	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CA604_RS03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CA604_RS03050	COG1049	propionate catabolic process, 2-methylcitrate cycle
CA604_RS03070	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CA604_RS03075	COG0671	phosphoesterase, PA-phosphatase related
CA604_RS03095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CA604_RS03125	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CA604_RS03130	COG0425	Belongs to the sulfur carrier protein TusA family
CA604_RS03135	COG0228	four-way junction DNA binding
CA604_RS03140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CA604_RS03145	COG0336	Belongs to the RNA methyltransferase TrmD family
CA604_RS03150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CA604_RS03160	COG1104	cysteine desulfurase activity
CA604_RS03165	COG0822	iron-sulfur transferase activity
CA604_RS03170	COG0316	Belongs to the HesB IscA family
CA604_RS03175	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CA604_RS03180	COG0443	Heat shock 70 kDa protein
CA604_RS03185	COG0633	Ferredoxin
CA604_RS03215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CA604_RS03220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CA604_RS03225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CA604_RS03240	COG1136	(ABC) transporter
CA604_RS03250	COG0084	hydrolase, TatD family'
CA604_RS03260	COG0613	PHP domain protein
CA604_RS03270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CA604_RS03275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA604_RS03280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CA604_RS03285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CA604_RS03290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CA604_RS03295	COG0072	phenylalanine-tRNA ligase activity
CA604_RS03295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CA604_RS03300	COG0776	regulation of translation
CA604_RS03310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CA604_RS03315	COG1304	FMN binding
CA604_RS03320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CA604_RS03330	COG0210	DNA helicase
CA604_RS03335	COG1610	YqeY-like protein
CA604_RS03345	COG1686	Belongs to the peptidase S11 family
CA604_RS03350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CA604_RS03350	COG0047	phosphoribosylformylglycinamidine synthase activity
CA604_RS03365	COG0519	Catalyzes the synthesis of GMP from XMP
CA604_RS03365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CA604_RS03400	COG4145	pantothenate transmembrane transporter activity
CA604_RS03410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CA604_RS03415	COG4166	transmembrane transport
CA604_RS03435	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CA604_RS03465	COG1132	(ABC) transporter
CA604_RS03470	COG1132	(ABC) transporter
CA604_RS03475	COG0786	glutamate:sodium symporter activity
CA604_RS03490	COG0280	phosphate acetyltransferase
CA604_RS03490	COG0281	malic enzyme
CA604_RS03495	COG0567	Dehydrogenase, E1 component
CA604_RS03500	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA604_RS03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA604_RS03510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CA604_RS03530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA604_RS03535	COG1758	RNA polymerase activity
CA604_RS03540	COG0194	GDP metabolic process
CA604_RS03545	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CA604_RS03550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CA604_RS03575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CA604_RS03585	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CA604_RS03590	COG3842	ATPase activity
CA604_RS03595	COG1176	ABC-type spermidine putrescine transport system, permease component I
CA604_RS03600	COG1177	transmembrane transport
CA604_RS03610	COG0704	Plays a role in the regulation of phosphate uptake
CA604_RS03615	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CA604_RS03620	COG1643	Atp-dependent helicase
CA604_RS03635	COG1132	(ABC) transporter
CA604_RS03640	COG1530	ribonuclease E activity
CA604_RS03645	COG0302	gtp cyclohydrolase
CA604_RS03705	COG2833	Protein of unknown function (DUF455)
CA604_RS03710	COG4178	(ABC) transporter
CA604_RS03725	COG0730	response to heat
CA604_RS03730	COG0557	exoribonuclease II activity
CA604_RS03735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA604_RS03740	COG0626	cystathionine gamma-synthase activity
CA604_RS03745	COG0776	regulation of translation
CA604_RS03755	COG1129	ABC transporter
CA604_RS03755	COG0842	Transport permease protein
CA604_RS03760	COG0842	Transport permease protein
CA604_RS03775	COG0137	argininosuccinate synthase activity
CA604_RS03780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CA604_RS03790	COG0268	Binds directly to 16S ribosomal RNA
CA604_RS03795	COG0728	peptidoglycan biosynthetic process
CA604_RS03800	COG0563	adenylate kinase activity
CA604_RS03805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CA604_RS03810	COG2835	tetraacyldisaccharide 4'-kinase activity
CA604_RS03820	COG1570	exodeoxyribonuclease VII activity
CA604_RS03825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CA604_RS03850	COG0411	ABC transporter
CA604_RS03860	COG1999	signal sequence binding
CA604_RS03865	COG0339	signal peptide processing
CA604_RS03870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CA604_RS03890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CA604_RS03895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CA604_RS03900	COG3038	cytochrome b561
CA604_RS03905	COG0285	dihydrofolate synthase activity
CA604_RS03915	COG1286	toxin biosynthetic process
CA604_RS03940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CA604_RS03945	COG0024	Methionine aminopeptidase
CA604_RS03950	COG0052	Belongs to the universal ribosomal protein uS2 family
CA604_RS03955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CA604_RS03960	COG0528	UMP kinase activity
CA604_RS03965	COG0233	cytoplasmic translational termination
CA604_RS03970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CA604_RS03975	COG0575	Belongs to the CDS family
CA604_RS03980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CA604_RS03985	COG0750	zinc metalloprotease
CA604_RS04000	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA604_RS04005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CA604_RS04010	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA604_RS04015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CA604_RS04020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CA604_RS04030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CA604_RS04035	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CA604_RS04055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CA604_RS04065	COG2914	Belongs to the UPF0125 (RnfH) family
CA604_RS04075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CA604_RS04080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CA604_RS04085	COG0470	DNA polymerase III
CA604_RS04090	COG0084	hydrolase, TatD family'
CA604_RS04100	COG1320	monovalent cation:proton antiporter activity
CA604_RS04105	COG2212	antiporter activity
CA604_RS04110	COG1863	multisubunit Na H antiporter MnhE subunit
CA604_RS04115	COG0651	ATP synthesis coupled electron transport
CA604_RS04120	COG1006	Multisubunit Na H antiporter MnhC subunit
CA604_RS04125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CA604_RS04125	COG2111	Na H antiporter
CA604_RS04150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CA604_RS04155	COG0778	Nitroreductase
CA604_RS04185	COG0697	spore germination
CA604_RS04195	COG3181	Tripartite tricarboxylate transporter family receptor
CA604_RS04205	COG0708	Exodeoxyribonuclease III
CA604_RS04215	COG1187	pseudouridine synthase activity
CA604_RS04225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CA604_RS04225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA604_RS04230	COG0165	Argininosuccinate lyase
CA604_RS04235	COG0859	PFAM glycosyl transferase family 9
CA604_RS04240	COG2137	regulation of response to DNA damage stimulus
CA604_RS04245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CA604_RS04260	COG0556	nucleotide-excision repair
CA604_RS04270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CA604_RS04280	COG2358	TRAP transporter, solute receptor (TAXI family
CA604_RS04290	COG0628	permease
CA604_RS04315	COG2171	N-acyltransferase activity
CA604_RS04320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CA604_RS04325	COG2890	protein-(glutamine-N5) methyltransferase activity
CA604_RS04330	COG0488	(ABC) transporter
CA604_RS04340	COG4120	Belongs to the binding-protein-dependent transport system permease family
CA604_RS04350	COG0101	tRNA pseudouridine synthase activity
CA604_RS04355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CA604_RS04360	COG0473	3-isopropylmalate dehydrogenase activity
CA604_RS04380	COG1295	ribonuclease BN
CA604_RS04385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CA604_RS04390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CA604_RS04395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CA604_RS04400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CA604_RS04405	COG0038	chloride channel
CA604_RS04410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CA604_RS04425	COG2086	electron transfer activity
CA604_RS04435	COG0322	excinuclease ABC activity
CA604_RS04440	COG1472	Belongs to the glycosyl hydrolase 3 family
CA604_RS04445	COG0736	holo-[acyl-carrier-protein] synthase activity
CA604_RS04450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CA604_RS04455	COG1162	GTPase activity
CA604_RS04460	COG0335	large ribosomal subunit rRNA binding
CA604_RS04485	COG4964	Belongs to the GSP D family
CA604_RS04515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CA604_RS04525	COG0582	viral genome integration into host DNA
CA604_RS04575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CA604_RS04580	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CA604_RS04585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CA604_RS04590	COG0330	HflC and HflK could
CA604_RS04595	COG0330	HflC and HflK could
CA604_RS04600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CA604_RS04605	COG1923	regulation of RNA biosynthetic process
CA604_RS04610	COG1160	GTP binding
CA604_RS04615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA604_RS04620	COG2976	Protein conserved in bacteria
CA604_RS04625	COG0124	histidyl-tRNA synthetase
CA604_RS04640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CA604_RS04645	COG0105	UTP biosynthetic process
CA604_RS04650	COG0525	valine-tRNA ligase activity
CA604_RS04660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CA604_RS04680	COG0181	hydroxymethylbilane synthase activity
CA604_RS04685	COG0861	Integral membrane protein TerC family
CA604_RS04690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CA604_RS04695	COG0045	succinate-CoA ligase (ADP-forming) activity
CA604_RS04705	COG0405	Gamma-glutamyltransferase
CA604_RS04715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CA604_RS04725	COG4942	peptidase
CA604_RS04730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CA604_RS04740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CA604_RS04745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CA604_RS04750	COG2252	PERMEase
CA604_RS04760	COG0488	(ABC) transporter
CA604_RS04765	COG1619	proteins homologs of microcin C7 resistance protein MccF
CA604_RS04800	COG1629	transport
CA604_RS04800	COG4206	TonB-dependent receptor
CA604_RS04805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CA604_RS04840	COG0523	cobalamin synthesis protein
CA604_RS04865	COG1840	ABC-type Fe3 transport system, periplasmic component
CA604_RS04885	COG0372	Belongs to the citrate synthase family
CA604_RS04890	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CA604_RS04895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CA604_RS04900	COG1053	succinate dehydrogenase
CA604_RS04915	COG0039	L-malate dehydrogenase activity
CA604_RS04950	COG3209	COG3209 Rhs family protein
CA604_RS04960	COG3209	COG3209 Rhs family protein
CA604_RS04970	COG3209	COG3209 Rhs family protein
CA604_RS04980	COG3209	COG3209 Rhs family protein
CA604_RS05040	COG0542	response to heat
CA604_RS05050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CA604_RS05055	COG0148	phosphopyruvate hydratase activity
CA604_RS05060	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CA604_RS05065	COG0504	CTP synthase activity
CA604_RS05075	COG0583	DNA-binding transcription factor activity
CA604_RS05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CA604_RS05085	COG1757	Na H antiporter
CA604_RS05090	COG1012	belongs to the aldehyde dehydrogenase family
CA604_RS05095	COG2423	ornithine cyclodeaminase activity
CA604_RS05100	COG1301	dicarboxylic acid transport
CA604_RS05105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CA604_RS05110	COG5383	Protein conserved in bacteria
CA604_RS05145	COG2841	Protein conserved in bacteria
CA604_RS05155	COG1629	transport
CA604_RS05155	COG4206	TonB-dependent receptor
CA604_RS05165	COG0748	coenzyme F420 binding
CA604_RS05180	COG1217	gtp-binding protein TYPA
CA604_RS05185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CA604_RS05190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CA604_RS05195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CA604_RS05200	COG2251	uridine kinase activity
CA604_RS05200	COG0195	Participates in both transcription termination and antitermination
CA604_RS05205	COG0779	Required for maturation of 30S ribosomal subunits
CA604_RS05210	COG1187	pseudouridine synthase activity
CA604_RS05215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CA604_RS05235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CA604_RS05245	COG0210	DNA helicase
CA604_RS05250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CA604_RS05250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CA604_RS05255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CA604_RS05260	COG0196	riboflavin kinase activity
CA604_RS05265	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CA604_RS05275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CA604_RS05285	COG0756	dUTP diphosphatase activity
CA604_RS05290	COG1629	transport
CA604_RS05290	COG4771	TonB-dependent receptor
CA604_RS05305	COG0542	response to heat
CA604_RS05310	COG1278	Cold shock
CA604_RS05320	COG0583	DNA-binding transcription factor activity
CA604_RS05325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CA604_RS05335	COG1840	ABC-type Fe3 transport system, periplasmic component
CA604_RS05340	COG1178	ABC-type Fe3 transport system permease component
CA604_RS05345	COG3842	ATPase activity
CA604_RS05360	COG0174	glutamine synthetase
CA604_RS05365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CA604_RS05370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CA604_RS05375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CA604_RS05380	COG1561	YicC-like family, N-terminal region
CA604_RS05385	COG0305	Participates in initiation and elongation during chromosome replication
CA604_RS05395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CA604_RS05405	COG0360	Binds together with S18 to 16S ribosomal RNA
CA604_RS05410	COG1469	GTP cyclohydrolase I activity
CA604_RS05415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CA604_RS05420	COG0142	geranyltranstransferase activity
CA604_RS05425	COG1722	exodeoxyribonuclease VII activity
CA604_RS05435	COG1228	amidohydrolase
CA604_RS05440	COG2986	histidine ammonia-lyase
CA604_RS05445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CA604_RS05450	COG2188	Transcriptional regulator
CA604_RS05465	COG0501	Belongs to the peptidase M48B family
CA604_RS05470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA604_RS05470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CA604_RS05475	COG1611	Belongs to the LOG family
CA604_RS05480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CA604_RS05490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CA604_RS05495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CA604_RS05505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CA604_RS05510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CA604_RS05520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CA604_RS05530	COG0740	serine-type endopeptidase activity
CA604_RS05535	COG0544	peptidyl-prolyl cis-trans isomerase activity
CA604_RS05545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CA604_RS05550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CA604_RS05590	COG3451	type IV secretory pathway VirB4
CA604_RS05830	COG0582	viral genome integration into host DNA
CA604_RS05845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CA604_RS05855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CA604_RS05860	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CA604_RS05890	COG1136	(ABC) transporter
CA604_RS05890	COG0577	efflux transmembrane transporter activity
CA604_RS05900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CA604_RS05920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CA604_RS05930	COG1185	polyribonucleotide nucleotidyltransferase activity
CA604_RS05935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CA604_RS05945	COG1115	amino acid carrier protein
CA604_RS05950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CA604_RS05955	COG0440	acetolactate synthase activity
CA604_RS05960	COG0028	Belongs to the TPP enzyme family
CA604_RS05965	COG3022	response to hydroperoxide
CA604_RS05970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CA604_RS05975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CA604_RS05985	COG1674	ftsk spoiiie
CA604_RS05990	COG0492	ferredoxin-NADP+ reductase activity
CA604_RS06000	COG2707	UPF0756 membrane protein
CA604_RS06010	COG2855	membrane
CA604_RS06025	COG0484	heat shock protein binding
CA604_RS06030	COG0443	Heat shock 70 kDa protein
CA604_RS06035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CA604_RS06045	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CA604_RS06050	COG1420	regulation of RNA biosynthetic process
CA604_RS06060	COG0497	DNA recombination
CA604_RS06065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CA604_RS06070	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CA604_RS06075	COG0735	belongs to the Fur family
CA604_RS06080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CA604_RS06090	COG1230	cation diffusion facilitator family transporter
CA604_RS06105	COG2837	iron assimilation
CA604_RS06115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CA604_RS06135	COG0248	Ppx GppA phosphatase
CA604_RS06145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CA604_RS06150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CA604_RS06155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CA604_RS06160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CA604_RS06165	COG1534	Rna-binding protein
CA604_RS06170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CA604_RS06175	COG2233	PERMEase
CA604_RS06185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CA604_RS06190	COG0505	Belongs to the CarA family
CA604_RS06195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CA604_RS06210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CA604_RS06220	COG1074	ATP-dependent DNA helicase activity
CA604_RS06240	COG3384	dioxygenase
CA604_RS06275	COG4974	Belongs to the 'phage' integrase family
CA604_RS06280	COG0802	atpase or kinase
CA604_RS06285	COG0860	N-Acetylmuramoyl-L-alanine amidase
CA604_RS06290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CA604_RS06295	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CA604_RS06300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CA604_RS06305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CA604_RS06310	COG0617	tRNA 3'-terminal CCA addition
CA604_RS06315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CA604_RS06330	COG3258	Cytochrome c
CA604_RS06370	COG0167	dihydroorotate dehydrogenase activity
CA604_RS06380	COG0513	Belongs to the DEAD box helicase family
CA604_RS06400	COG0138	bifunctional purine biosynthesis protein purh
CA604_RS06405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CA604_RS06410	COG0632	four-way junction helicase activity
CA604_RS06440	COG2022	thiamine diphosphate biosynthetic process
CA604_RS06485	COG2239	Acts as a magnesium transporter
CA604_RS06490	COG0653	protein targeting
CA604_RS06495	COG0739	heme binding
CA604_RS06505	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CA604_RS06510	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CA604_RS06520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CA604_RS06525	COG1181	Belongs to the D-alanine--D-alanine ligase family
CA604_RS06530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA604_RS06535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CA604_RS06540	COG0772	Belongs to the SEDS family
CA604_RS06545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CA604_RS06550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CA604_RS06555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CA604_RS06570	COG0275	rRNA processing
CA604_RS06575	COG2001	Belongs to the MraZ family
CA604_RS06585	COG0753	catalase activity
CA604_RS06590	COG0752	glycyl-tRNA synthetase alpha subunit
CA604_RS06595	COG0751	glycine-tRNA ligase activity
CA604_RS06600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CA604_RS06615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CA604_RS06620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CA604_RS06655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA604_RS06660	COG0850	regulation of cytokinetic process
CA604_RS06665	COG2894	cell division
CA604_RS06670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CA604_RS06680	COG0488	(ABC) transporter
CA604_RS06690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CA604_RS06695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CA604_RS06700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CA604_RS06705	COG0259	pyridoxamine-phosphate oxidase activity
CA604_RS06710	COG1858	cytochrome C peroxidase
CA604_RS06715	COG0009	L-threonylcarbamoyladenylate synthase
CA604_RS06720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CA604_RS06725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CA604_RS06730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CA604_RS06740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CA604_RS06745	COG0126	phosphoglycerate kinase activity
CA604_RS06750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CA604_RS06755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CA604_RS06760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CA604_RS06775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CA604_RS06800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CA604_RS06805	COG0343	queuine tRNA-ribosyltransferase activity
CA604_RS06810	COG1862	Preprotein translocase
CA604_RS06815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA604_RS06820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CA604_RS06825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CA604_RS06830	COG1702	phosphate starvation-inducible protein PhoH
CA604_RS06835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CA604_RS06840	COG4535	Mg2 and Co2 transporter CorC
CA604_RS06865	COG4172	Belongs to the ABC transporter superfamily
CA604_RS06870	COG0747	negative chemotaxis
CA604_RS06875	COG0601	transmembrane transport
CA604_RS06880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CA604_RS06900	COG0328	RNA-DNA hybrid ribonuclease activity
CA604_RS06910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CA604_RS06915	COG0741	lytic transglycosylase activity
CA604_RS06915	COG1388	LysM domain
CA604_RS06935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA604_RS06935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CA604_RS06940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CA604_RS06945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CA604_RS06950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CA604_RS06955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CA604_RS06960	COG0316	Belongs to the HesB IscA family
CA604_RS06970	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CA604_RS06975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CA604_RS06980	COG0312	modulator of DNA gyrase
CA604_RS06990	COG0400	carboxylic ester hydrolase activity
CA604_RS06995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CA604_RS07010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CA604_RS07020	COG2264	protein methyltransferase activity
CA604_RS07030	COG0511	ligase activity, forming carbon-carbon bonds
CA604_RS07035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CA604_RS07040	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CA604_RS07065	COG0540	Belongs to the ATCase OTCase family
CA604_RS07070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CA604_RS07080	COG1773	rubredoxin
CA604_RS07085	COG0352	thiamine-phosphate diphosphorylase activity
CA604_RS07090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CA604_RS07095	COG0513	Belongs to the DEAD box helicase family
CA604_RS07105	COG0617	tRNA 3'-terminal CCA addition
CA604_RS07130	COG3209	COG3209 Rhs family protein
CA604_RS07140	COG3209	COG3209 Rhs family protein
CA604_RS07160	COG2879	small protein
CA604_RS07165	COG1966	Carbon starvation protein
CA604_RS07180	COG3180	Ammonia monooxygenase
CA604_RS07200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CA604_RS07205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CA604_RS07210	COG1560	Kdo2-lipid A biosynthetic process
CA604_RS07215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CA604_RS07220	COG0708	Exodeoxyribonuclease III
CA604_RS07230	COG2223	nitrite transmembrane transporter activity
CA604_RS07235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CA604_RS07240	COG3245	cytochrome
CA604_RS07280	COG4566	intracellular signal transduction
CA604_RS07295	COG3258	Cytochrome c
CA604_RS07300	COG1858	cytochrome C peroxidase
CA604_RS07355	COG2969	positive regulation of protein catabolic process
CA604_RS07360	COG0625	glutathione transferase activity
CA604_RS07365	COG2857	Cytochrome c1
CA604_RS07370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CA604_RS07375	COG0723	plastoquinol--plastocyanin reductase activity
CA604_RS07380	COG1970	mechanosensitive ion channel activity
CA604_RS07385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CA604_RS07390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CA604_RS07395	COG0805	protein transport
CA604_RS07400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA604_RS07405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CA604_RS07410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CA604_RS07415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CA604_RS07425	COG0842	Transport permease protein
CA604_RS07430	COG1131	(ABC) transporter
CA604_RS07440	COG2853	Lipoprotein
CA604_RS07445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CA604_RS07450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CA604_RS07455	COG1127	ABC transporter
CA604_RS07460	COG0758	DNA mediated transformation
CA604_RS07465	COG0242	peptide deformylase activity
CA604_RS07470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CA604_RS07475	COG1253	flavin adenine dinucleotide binding
CA604_RS07505	COG2814	Major facilitator Superfamily
CA604_RS07520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CA604_RS07530	COG0019	diaminopimelate decarboxylase activity
CA604_RS07540	COG1965	Belongs to the frataxin family
CA604_RS07545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CA604_RS07550	COG1333	cytochrome c biogenesis protein
CA604_RS07560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CA604_RS07575	COG4232	protein-disulfide reductase activity
CA604_RS07585	COG0786	glutamate:sodium symporter activity
CA604_RS07590	COG0010	Belongs to the arginase family
CA604_RS07605	COG0203	ribosomal protein L17
CA604_RS07610	COG0202	RNA polymerase activity
CA604_RS07615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CA604_RS07620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CA604_RS07625	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CA604_RS07630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CA604_RS07640	COG0201	protein transport
CA604_RS07645	COG0200	Binds to the 23S rRNA
CA604_RS07650	COG1841	ribosomal large subunit assembly
CA604_RS07655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CA604_RS07660	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CA604_RS07670	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CA604_RS07675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CA604_RS07680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CA604_RS07685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CA604_RS07690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CA604_RS07695	COG2056	Na+-H+ antiporter family
CA604_RS07700	COG2056	Na+-H+ antiporter family
CA604_RS07705	COG2132	Multicopper oxidase
CA604_RS07710	COG1999	signal sequence binding
CA604_RS07720	COG2217	Heavy metal translocating P-type atpase
CA604_RS07740	COG0625	glutathione transferase activity
CA604_RS07745	COG1373	ATPase (AAA superfamily
CA604_RS07780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CA604_RS07785	COG0255	Belongs to the universal ribosomal protein uL29 family
CA604_RS07790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CA604_RS07795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CA604_RS07800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CA604_RS07805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CA604_RS07810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CA604_RS07815	COG0089	rRNA binding
CA604_RS07820	COG0088	Forms part of the polypeptide exit tunnel
CA604_RS07825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CA604_RS07830	COG1322	Protein conserved in bacteria
CA604_RS07845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CA604_RS07865	COG0051	transcription antitermination factor activity, RNA binding
CA604_RS07870	COG1132	(ABC) transporter
CA604_RS07880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA604_RS07885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CA604_RS07890	COG0049	tRNA binding
CA604_RS07895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CA604_RS07915	COG2301	Belongs to the HpcH HpaI aldolase family
CA604_RS07925	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CA604_RS07930	COG1960	acyl-CoA dehydrogenase activity
CA604_RS07955	COG3313	Fe-S protein
CA604_RS07960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CA604_RS07965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CA604_RS07970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CA604_RS07985	COG0010	Belongs to the arginase family
CA604_RS07990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CA604_RS07995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CA604_RS08000	COG0085	RNA polymerase activity
CA604_RS08005	COG0222	ribosome binding
CA604_RS08010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CA604_RS08015	COG0081	regulation of translation
CA604_RS08020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CA604_RS08040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CA604_RS08065	COG1475	DNA binding
CA604_RS08070	COG1192	Involved in chromosome partitioning
CA604_RS08075	COG0357	Ribosomal RNA small subunit methyltransferase G
CA604_RS08080	COG0445	tRNA wobble uridine modification
CA604_RS08085	COG0537	adenosine 5'-monophosphoramidase activity
CA604_RS08095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CA604_RS08100	COG0594	ribonuclease P activity
CA604_RS08105	COG0230	Belongs to the bacterial ribosomal protein bL34 family