locus-tag	class	description
B9C57_RS00030	COG4942	peptidase
B9C57_RS00055	COG1522	sequence-specific DNA binding
B9C57_RS00065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B9C57_RS00090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B9C57_RS00110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B9C57_RS00130	COG1519	Transferase
B9C57_RS00130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B9C57_RS00140	COG0439	Biotin carboxylase
B9C57_RS00145	COG0511	ligase activity, forming carbon-carbon bonds
B9C57_RS00150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9C57_RS00155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B9C57_RS00165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B9C57_RS00195	COG0109	protoheme IX farnesyltransferase activity
B9C57_RS00200	COG1845	cytochrome c oxidase, subunit III
B9C57_RS00205	COG1845	cytochrome c oxidase, subunit III
B9C57_RS00220	COG1999	signal sequence binding
B9C57_RS00225	COG2322	membrane
B9C57_RS00245	COG0668	transmembrane transport
B9C57_RS00260	COG3341	Caulimovirus viroplasmin
B9C57_RS00260	COG0328	RNA-DNA hybrid ribonuclease activity
B9C57_RS00270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B9C57_RS00275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B9C57_RS00280	COG0571	ribonuclease III activity
B9C57_RS00290	COG0469	pyruvate kinase activity
B9C57_RS00300	COG0629	single-stranded DNA binding
B9C57_RS00310	COG0010	Belongs to the arginase family
B9C57_RS00315	COG1166	arginine decarboxylase activity
B9C57_RS00360	COG2003	Belongs to the UPF0758 family
B9C57_RS00460	COG1309	transcriptional regulator
B9C57_RS00500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9C57_RS00515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B9C57_RS00520	COG1968	undecaprenyl-diphosphatase activity
B9C57_RS00530	COG2177	Part of the ABC transporter FtsEX involved in
B9C57_RS00535	COG0346	lactoylglutathione lyase activity
B9C57_RS00540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B9C57_RS00545	COG4591	ABC-type transport system involved in lipoprotein release permease component
B9C57_RS00560	COG0481	GTPase activity
B9C57_RS00570	COG0252	asparaginase activity
B9C57_RS00575	COG0811	peptide transport
B9C57_RS00605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B9C57_RS00610	COG0017	Asparaginyl-tRNA synthetase
B9C57_RS00620	COG0233	cytoplasmic translational termination
B9C57_RS00625	COG0528	UMP kinase activity
B9C57_RS00630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B9C57_RS00635	COG0052	Belongs to the universal ribosomal protein uS2 family
B9C57_RS00640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B9C57_RS00645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B9C57_RS00660	COG1477	protein flavinylation
B9C57_RS00680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B9C57_RS00705	COG0437	4 iron, 4 sulfur cluster binding
B9C57_RS00710	COG0693	protein deglycase activity
B9C57_RS00760	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B9C57_RS00780	COG0702	epimerase
B9C57_RS00785	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS00795	COG0386	Belongs to the glutathione peroxidase family
B9C57_RS00805	COG0415	Belongs to the DNA photolyase family
B9C57_RS00825	COG0583	DNA-binding transcription factor activity
B9C57_RS00925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B9C57_RS00960	COG2363	Small membrane protein
B9C57_RS00965	COG0668	transmembrane transport
B9C57_RS00990	COG0492	ferredoxin-NADP+ reductase activity
B9C57_RS01000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9C57_RS01035	COG0137	argininosuccinate synthase activity
B9C57_RS01040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B9C57_RS01045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B9C57_RS01050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9C57_RS01060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B9C57_RS01070	COG0165	Argininosuccinate lyase
B9C57_RS01085	COG1160	GTP binding
B9C57_RS01095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B9C57_RS01150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9C57_RS01150	COG1333	cytochrome c biogenesis protein
B9C57_RS01165	COG0183	Belongs to the thiolase family
B9C57_RS01195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9C57_RS01215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B9C57_RS01225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B9C57_RS01230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B9C57_RS01260	COG0438	transferase activity, transferring glycosyl groups
B9C57_RS01270	COG0778	Nitroreductase
B9C57_RS01275	COG1012	belongs to the aldehyde dehydrogenase family
B9C57_RS01280	COG0564	pseudouridine synthase activity
B9C57_RS01285	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B9C57_RS01295	COG2001	Belongs to the MraZ family
B9C57_RS01300	COG0275	rRNA processing
B9C57_RS01310	COG0768	penicillin binding
B9C57_RS01315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B9C57_RS01320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B9C57_RS01325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B9C57_RS01335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B9C57_RS01340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9C57_RS01355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B9C57_RS01360	COG1610	YqeY-like protein
B9C57_RS01430	COG2239	Acts as a magnesium transporter
B9C57_RS01460	COG0348	domain, Protein
B9C57_RS01465	COG2010	Cytochrome c
B9C57_RS01475	COG3278	Belongs to the heme-copper respiratory oxidase family
B9C57_RS01485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9C57_RS01490	COG0813	purine-nucleoside phosphorylase activity
B9C57_RS01495	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B9C57_RS01510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B9C57_RS01515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B9C57_RS01540	COG2226	methyltransferase
B9C57_RS01545	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B9C57_RS01560	COG0442	prolyl-tRNA aminoacylation
B9C57_RS01575	COG0268	Binds directly to 16S ribosomal RNA
B9C57_RS01630	COG0772	Belongs to the SEDS family
B9C57_RS01635	COG0768	penicillin binding
B9C57_RS01650	COG1077	Cell shape determining protein MreB Mrl
B9C57_RS01655	COG0138	bifunctional purine biosynthesis protein purh
B9C57_RS01680	COG1187	pseudouridine synthase activity
B9C57_RS01705	COG0616	signal peptide processing
B9C57_RS01715	COG0519	Catalyzes the synthesis of GMP from XMP
B9C57_RS01735	COG0300	oxidoreductase activity
B9C57_RS01765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9C57_RS01775	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B9C57_RS01775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9C57_RS01780	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B9C57_RS01835	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B9C57_RS01840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B9C57_RS01845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B9C57_RS01850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B9C57_RS01860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9C57_RS01865	COG2197	response regulator
B9C57_RS01900	COG2315	Protein conserved in bacteria
B9C57_RS01910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9C57_RS01920	COG3938	Belongs to the proline racemase family
B9C57_RS01925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B9C57_RS01930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B9C57_RS02080	COG3152	Membrane
B9C57_RS02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B9C57_RS02130	COG0101	tRNA pseudouridine synthase activity
B9C57_RS02135	COG1132	(ABC) transporter
B9C57_RS02145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B9C57_RS02150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B9C57_RS02165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B9C57_RS02255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B9C57_RS02260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B9C57_RS02285	COG0459	protein refolding
B9C57_RS02290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B9C57_RS02310	COG3604	Transcriptional regulator
B9C57_RS02315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9C57_RS02325	COG0010	Belongs to the arginase family
B9C57_RS02330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9C57_RS02360	COG0488	(ABC) transporter
B9C57_RS02395	COG3279	Response regulator of the LytR AlgR family
B9C57_RS02400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B9C57_RS02420	COG3023	N-Acetylmuramoyl-L-alanine amidase
B9C57_RS02435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B9C57_RS02460	COG1253	flavin adenine dinucleotide binding
B9C57_RS02465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9C57_RS02500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B9C57_RS02505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B9C57_RS02515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B9C57_RS02520	COG0537	adenosine 5'-monophosphoramidase activity
B9C57_RS02525	COG4191	Histidine kinase
B9C57_RS02530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B9C57_RS02550	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B9C57_RS02555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B9C57_RS02580	COG0542	response to heat
B9C57_RS02655	COG3501	Rhs element vgr protein
B9C57_RS02665	COG3209	COG3209 Rhs family protein
B9C57_RS02675	COG2176	DNA-directed DNA polymerase activity
B9C57_RS02690	COG3209	COG3209 Rhs family protein
B9C57_RS02690	COG4104	PAAR repeat-containing protein
B9C57_RS02770	COG4104	PAAR repeat-containing protein
B9C57_RS02770	COG3209	COG3209 Rhs family protein
B9C57_RS02785	COG1032	radical SAM domain protein
B9C57_RS02795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B9C57_RS02820	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B9C57_RS02840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9C57_RS02850	COG0545	Peptidyl-prolyl cis-trans isomerase
B9C57_RS02875	COG2884	Cell division ATP-binding protein ftsE
B9C57_RS02905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B9C57_RS02905	COG0519	Catalyzes the synthesis of GMP from XMP
B9C57_RS02910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9C57_RS02915	COG0295	cytidine deaminase activity
B9C57_RS02930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B9C57_RS02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B9C57_RS02955	COG1333	cytochrome c biogenesis protein
B9C57_RS02955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9C57_RS02960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS02960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS02965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS02965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS02975	COG0572	uridine kinase
B9C57_RS03220	COG4974	Belongs to the 'phage' integrase family
B9C57_RS03230	COG0492	ferredoxin-NADP+ reductase activity
B9C57_RS03240	COG1960	acyl-CoA dehydrogenase activity
B9C57_RS03245	COG0183	Belongs to the thiolase family
B9C57_RS03250	COG1024	Enoyl-CoA hydratase
B9C57_RS03250	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9C57_RS03260	COG4152	abc transporter atp-binding protein
B9C57_RS03265	COG1668	transmembrane transport
B9C57_RS03275	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B9C57_RS03280	COG0450	alkyl hydroperoxide reductase
B9C57_RS03295	COG0456	acetyltransferase
B9C57_RS03310	COG0778	Nitroreductase
B9C57_RS03340	COG1611	Belongs to the LOG family
B9C57_RS03345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9C57_RS03365	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B9C57_RS03375	COG1115	amino acid carrier protein
B9C57_RS03385	COG1960	acyl-CoA dehydrogenase activity
B9C57_RS03390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B9C57_RS03445	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B9C57_RS03450	COG0081	regulation of translation
B9C57_RS03455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B9C57_RS03460	COG0222	ribosome binding
B9C57_RS03465	COG0085	RNA polymerase activity
B9C57_RS03470	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B9C57_RS03480	COG0076	glutamate decarboxylase activity
B9C57_RS03485	COG2813	Specifically methylates the guanine in position
B9C57_RS03490	COG0069	glutamate synthase activity
B9C57_RS03495	COG0254	rRNA binding
B9C57_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS03515	COG3091	SprT-like family
B9C57_RS03550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B9C57_RS03570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B9C57_RS03585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B9C57_RS03590	COG1663	tetraacyldisaccharide 4'-kinase activity
B9C57_RS03595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS03605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9C57_RS03605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B9C57_RS03730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9C57_RS03740	COG3844	kynureninase activity
B9C57_RS03745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B9C57_RS03775	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS03780	COG0662	Cupin 2, conserved barrel domain protein
B9C57_RS03855	COG1629	transport
B9C57_RS03870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS03915	COG2274	protein secretion by the type I secretion system
B9C57_RS03935	COG0688	phosphatidylethanolamine metabolic process
B9C57_RS03940	COG4589	Belongs to the CDS family
B9C57_RS03950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B9C57_RS03955	COG0799	negative regulation of ribosome biogenesis
B9C57_RS03970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B9C57_RS03975	COG0494	nUDIX hydrolase
B9C57_RS03980	COG0443	Heat shock 70 kDa protein
B9C57_RS03995	COG1252	NADH dehydrogenase
B9C57_RS04025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B9C57_RS04030	COG2197	response regulator
B9C57_RS04100	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9C57_RS04140	COG4968	Prepilin-type N-terminal cleavage methylation domain
B9C57_RS04265	COG3608	succinylglutamate desuccinylase aspartoacylase
B9C57_RS04265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B9C57_RS04275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B9C57_RS04290	COG2326	polyphosphate kinase activity
B9C57_RS04305	COG1472	Belongs to the glycosyl hydrolase 3 family
B9C57_RS04320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B9C57_RS04415	COG1230	cation diffusion facilitator family transporter
B9C57_RS04425	COG0681	Belongs to the peptidase S26 family
B9C57_RS04430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B9C57_RS04440	COG1475	DNA binding
B9C57_RS04445	COG1192	Involved in chromosome partitioning
B9C57_RS04455	COG0592	DNA-directed DNA polymerase activity
B9C57_RS04460	COG0531	amino acid
B9C57_RS04470	COG2326	polyphosphate kinase activity
B9C57_RS04490	COG1104	cysteine desulfurase activity
B9C57_RS04530	COG2223	nitrite transmembrane transporter activity
B9C57_RS04535	COG0277	FAD linked oxidase domain protein
B9C57_RS04535	COG0247	lactate metabolic process
B9C57_RS04550	COG0401	homolog of Blt101
B9C57_RS04555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9C57_RS04555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9C57_RS04575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9C57_RS04585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B9C57_RS04590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9C57_RS04600	COG1482	cell wall glycoprotein biosynthetic process
B9C57_RS04610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B9C57_RS04615	COG1011	Hydrolase
B9C57_RS04640	COG1595	DNA-templated transcription, initiation
B9C57_RS04650	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B9C57_RS04655	COG3022	response to hydroperoxide
B9C57_RS04660	COG1760	l-serine dehydratase
B9C57_RS04675	COG0205	6-phosphofructokinase activity
B9C57_RS04685	COG1803	Methylglyoxal synthase
B9C57_RS04690	COG0251	oxidation-reduction process
B9C57_RS04700	COG0860	N-Acetylmuramoyl-L-alanine amidase
B9C57_RS04715	COG2181	nitrate reductase activity
B9C57_RS04715	COG0247	lactate metabolic process
B9C57_RS04720	COG2181	nitrate reductase activity
B9C57_RS04720	COG0247	lactate metabolic process
B9C57_RS04725	COG1575	Belongs to the MenA family. Type 1 subfamily
B9C57_RS04735	COG4948	Mandelate Racemase Muconate Lactonizing
B9C57_RS04740	COG1629	transport
B9C57_RS04765	COG1266	CAAX protease self-immunity
B9C57_RS04780	COG0415	Belongs to the DNA photolyase family
B9C57_RS04785	COG3046	protein related to deoxyribodipyrimidine photolyase
B9C57_RS04790	COG0446	pyridine nucleotide-disulphide oxidoreductase
B9C57_RS04790	COG1902	pentaerythritol trinitrate reductase activity
B9C57_RS04800	COG0488	(ABC) transporter
B9C57_RS04805	COG2095	MarC family integral membrane protein
B9C57_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS04815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9C57_RS04815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B9C57_RS04830	COG1674	ftsk spoiiie
B9C57_RS04840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B9C57_RS04845	COG0534	Mate efflux family protein
B9C57_RS04855	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9C57_RS04885	COG1418	mRNA catabolic process
B9C57_RS04895	COG1104	cysteine desulfurase activity
B9C57_RS04905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9C57_RS04905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9C57_RS04910	COG0640	Transcriptional regulator
B9C57_RS04920	COG0583	DNA-binding transcription factor activity
B9C57_RS04925	COG2986	histidine ammonia-lyase
B9C57_RS04930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B9C57_RS04955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B9C57_RS04960	COG1678	Uncharacterized ACR, COG1678
B9C57_RS04965	COG3279	Response regulator of the LytR AlgR family
B9C57_RS04970	COG0745	RESPONSE REGULATOR receiver
B9C57_RS04970	COG2972	Histidine kinase
B9C57_RS05000	COG4771	TonB-dependent receptor
B9C57_RS05015	COG3340	Belongs to the peptidase S51 family
B9C57_RS05020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B9C57_RS05050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B9C57_RS05055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B9C57_RS05060	COG0564	pseudouridine synthase activity
B9C57_RS05065	COG0688	phosphatidylethanolamine metabolic process
B9C57_RS05070	COG1022	Amp-dependent synthetase and ligase
B9C57_RS05075	COG1022	Amp-dependent synthetase and ligase
B9C57_RS05080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9C57_RS05090	COG0076	glutamate decarboxylase activity
B9C57_RS05105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS05115	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B9C57_RS05155	COG1703	isobutyryl-CoA mutase activity
B9C57_RS05160	COG0215	cysteine-tRNA ligase activity
B9C57_RS05165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B9C57_RS05170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B9C57_RS05175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B9C57_RS05180	COG0083	homoserine kinase activity
B9C57_RS05185	COG0460	homoserine dehydrogenase
B9C57_RS05185	COG0527	aspartate kinase activity
B9C57_RS05215	COG0488	(ABC) transporter
B9C57_RS05220	COG0583	DNA-binding transcription factor activity
B9C57_RS05225	COG0783	Belongs to the Dps family
B9C57_RS05230	COG1253	flavin adenine dinucleotide binding
B9C57_RS05250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9C57_RS05260	COG5002	protein histidine kinase activity
B9C57_RS05265	COG0745	RESPONSE REGULATOR receiver
B9C57_RS05275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B9C57_RS05290	COG1132	(ABC) transporter
B9C57_RS05295	COG2197	response regulator
B9C57_RS05300	COG4585	Histidine kinase
B9C57_RS05315	COG0343	queuine tRNA-ribosyltransferase activity
B9C57_RS05330	COG0825	malonyl-CoA metabolic process
B9C57_RS05335	COG0602	queuosine metabolic process
B9C57_RS05350	COG0433	COG0433 Predicted ATPase
B9C57_RS05360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B9C57_RS05360	COG0662	Cupin 2, conserved barrel domain protein
B9C57_RS05375	COG0116	Belongs to the methyltransferase superfamily
B9C57_RS05380	COG0776	regulation of translation
B9C57_RS05385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B9C57_RS05390	COG0514	ATP-dependent DNA helicase (RecQ)
B9C57_RS05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B9C57_RS05420	COG0714	Associated with various cellular activities
B9C57_RS05430	COG0326	Molecular chaperone. Has ATPase activity
B9C57_RS05435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B9C57_RS05445	COG1234	tRNA 3'-trailer cleavage
B9C57_RS05460	COG0540	Belongs to the ATCase OTCase family
B9C57_RS05465	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B9C57_RS05470	COG0659	secondary active sulfate transmembrane transporter activity
B9C57_RS05475	COG0129	dihydroxy-acid dehydratase activity
B9C57_RS05480	COG0028	Belongs to the TPP enzyme family
B9C57_RS05485	COG0440	acetolactate synthase activity
B9C57_RS05490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B9C57_RS05495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B9C57_RS05550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B9C57_RS05555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9C57_RS05565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B9C57_RS05575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B9C57_RS05580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B9C57_RS05590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9C57_RS05595	COG4206	TonB-dependent receptor
B9C57_RS05595	COG1629	transport
B9C57_RS05625	COG0012	GTP binding
B9C57_RS05665	COG0791	NLP P60 protein
B9C57_RS05665	COG1388	LysM domain
B9C57_RS05680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9C57_RS05685	COG0463	Glycosyl transferase, family 2
B9C57_RS05725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B9C57_RS05745	COG1183	phosphatidylcholine synthase activity
B9C57_RS05750	COG1137	ATPase activity
B9C57_RS05760	COG0805	protein transport
B9C57_RS05765	COG0517	IMP dehydrogenase activity
B9C57_RS05765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B9C57_RS05770	COG0514	ATP-dependent DNA helicase (RecQ)
B9C57_RS05780	COG0686	Belongs to the AlaDH PNT family
B9C57_RS05790	COG2204	response regulator
B9C57_RS05795	COG1078	dGTPase activity
B9C57_RS05800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9C57_RS05805	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B9C57_RS05805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B9C57_RS05810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9C57_RS05815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B9C57_RS05820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9C57_RS05825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B9C57_RS05830	COG0612	Peptidase, M16
B9C57_RS05850	COG0702	epimerase
B9C57_RS05855	COG0778	Nitroreductase
B9C57_RS05870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B9C57_RS05875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B9C57_RS05880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B9C57_RS05885	COG0131	Imidazoleglycerol-phosphate dehydratase
B9C57_RS05895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B9C57_RS05900	COG0107	imidazoleglycerol-phosphate synthase activity
B9C57_RS05905	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B9C57_RS05905	COG0140	phosphoribosyl-ATP diphosphatase activity
B9C57_RS05910	COG0697	spore germination
B9C57_RS05915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B9C57_RS05930	COG0513	Belongs to the DEAD box helicase family
B9C57_RS05935	COG0659	secondary active sulfate transmembrane transporter activity
B9C57_RS05945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B9C57_RS05950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9C57_RS05955	COG0019	diaminopimelate decarboxylase activity
B9C57_RS05960	COG2195	Cleaves the N-terminal amino acid of tripeptides
B9C57_RS05990	COG3959	Transketolase, thiamine diphosphate binding domain
B9C57_RS05995	COG0438	transferase activity, transferring glycosyl groups
B9C57_RS06000	COG2356	endonuclease I
B9C57_RS06015	COG0167	dihydroorotate dehydrogenase activity
B9C57_RS06025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B9C57_RS06030	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS06035	COG3956	TIGRFAM MazG family protein
B9C57_RS06045	COG0242	peptide deformylase activity
B9C57_RS06050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B9C57_RS06070	COG0009	L-threonylcarbamoyladenylate synthase
B9C57_RS06075	COG0617	tRNA 3'-terminal CCA addition
B9C57_RS06085	COG3958	Transketolase
B9C57_RS06090	COG0424	maF-like protein
B9C57_RS06095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B9C57_RS06100	COG3047	cAMP biosynthetic process
B9C57_RS06110	COG0542	response to heat
B9C57_RS06135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B9C57_RS06165	COG2003	Belongs to the UPF0758 family
B9C57_RS06190	COG2814	Major facilitator Superfamily
B9C57_RS06195	COG0564	pseudouridine synthase activity
B9C57_RS06205	COG1522	sequence-specific DNA binding
B9C57_RS06215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9C57_RS06225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B9C57_RS06245	COG1739	Uncharacterized protein family UPF0029
B9C57_RS06250	COG0697	spore germination
B9C57_RS06255	COG1011	Hydrolase
B9C57_RS06260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9C57_RS06260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B9C57_RS06270	COG0456	acetyltransferase
B9C57_RS06275	COG2890	protein-(glutamine-N5) methyltransferase activity
B9C57_RS06290	COG0628	permease
B9C57_RS06300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B9C57_RS06320	COG0450	alkyl hydroperoxide reductase
B9C57_RS06330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B9C57_RS06335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9C57_RS06335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B9C57_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
B9C57_RS06360	COG1217	gtp-binding protein TYPA
B9C57_RS06370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9C57_RS06375	COG2022	thiamine diphosphate biosynthetic process
B9C57_RS06380	COG0352	thiamine-phosphate diphosphorylase activity
B9C57_RS06385	COG0352	thiamine-phosphate diphosphorylase activity
B9C57_RS06385	COG0351	phosphomethylpyrimidine kinase
B9C57_RS06395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B9C57_RS06405	COG0668	transmembrane transport
B9C57_RS06445	COG0516	GMP reductase activity
B9C57_RS06445	COG0517	IMP dehydrogenase activity
B9C57_RS06500	COG0525	valine-tRNA ligase activity
B9C57_RS06515	COG0436	Aminotransferase
B9C57_RS06520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B9C57_RS06550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B9C57_RS06565	COG3876	Protein conserved in bacteria
B9C57_RS06580	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B9C57_RS06595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B9C57_RS06605	COG0668	transmembrane transport
B9C57_RS06620	COG0437	4 iron, 4 sulfur cluster binding
B9C57_RS06635	COG0243	molybdopterin cofactor binding
B9C57_RS06660	COG0427	acetyl-CoA hydrolase
B9C57_RS06665	COG1333	cytochrome c biogenesis protein
B9C57_RS06665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B9C57_RS06670	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B9C57_RS06675	COG3005	denitrification pathway
B9C57_RS06680	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B9C57_RS06715	COG0813	purine-nucleoside phosphorylase activity
B9C57_RS06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B9C57_RS06740	COG1250	3-hydroxyacyl-CoA dehydrogenase
B9C57_RS06750	COG1136	(ABC) transporter
B9C57_RS06750	COG0577	efflux transmembrane transporter activity
B9C57_RS06755	COG1136	(ABC) transporter
B9C57_RS06755	COG0577	efflux transmembrane transporter activity
B9C57_RS06760	COG1136	(ABC) transporter
B9C57_RS06765	COG3011	Protein conserved in bacteria
B9C57_RS06775	COG4206	TonB-dependent receptor
B9C57_RS06860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9C57_RS06875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B9C57_RS06880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B9C57_RS06900	COG1629	transport
B9C57_RS06900	COG4206	TonB-dependent receptor
B9C57_RS06915	COG0359	binds to the 23S rRNA
B9C57_RS06920	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B9C57_RS06925	COG0360	Binds together with S18 to 16S ribosomal RNA
B9C57_RS06930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B9C57_RS06935	COG4628	conserved protein (DUF2132)
B9C57_RS06945	COG0006	proline dipeptidase activity
B9C57_RS06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B9C57_RS06985	COG1607	acyl-coa hydrolase
B9C57_RS06995	COG2346	COG2346, Truncated hemoglobins
B9C57_RS07000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B9C57_RS07020	COG4953	penicillin-binding protein 1C
B9C57_RS07025	COG2373	Large extracellular alpha-helical protein
B9C57_RS07030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B9C57_RS07055	COG1482	cell wall glycoprotein biosynthetic process
B9C57_RS07100	COG3279	Response regulator of the LytR AlgR family
B9C57_RS07110	COG4251	negative regulation of phosphorylation
B9C57_RS07120	COG0784	Response regulator, receiver
B9C57_RS07130	COG3012	SEC-C Motif Domain Protein
B9C57_RS07165	COG1064	alcohol dehydrogenase
B9C57_RS07180	COG2270	Major facilitator Superfamily
B9C57_RS07195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9C57_RS07205	COG0563	adenylate kinase activity
B9C57_RS07220	COG4771	TonB-dependent receptor
B9C57_RS07230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B9C57_RS07240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B9C57_RS07245	COG0484	heat shock protein binding
B9C57_RS07250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B9C57_RS07255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B9C57_RS07280	COG1301	dicarboxylic acid transport
B9C57_RS07305	COG0494	nUDIX hydrolase
B9C57_RS07315	COG1363	Peptidase, m42
B9C57_RS07320	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B9C57_RS07325	COG1228	amidohydrolase
B9C57_RS07355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B9C57_RS07360	COG1393	Belongs to the ArsC family
B9C57_RS07365	COG1216	Glycosyl transferase, family 2
B9C57_RS07365	COG0463	Glycosyl transferase, family 2
B9C57_RS07375	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9C57_RS07385	COG0497	DNA recombination
B9C57_RS07410	COG1528	Iron-storage protein
B9C57_RS07415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B9C57_RS07425	COG0737	Belongs to the 5'-nucleotidase family
B9C57_RS07430	COG0737	Belongs to the 5'-nucleotidase family
B9C57_RS07445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9C57_RS07465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B9C57_RS07470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B9C57_RS07475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9C57_RS07480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B9C57_RS07490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B9C57_RS07495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B9C57_RS07500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B9C57_RS07505	COG0824	Thioesterase
B9C57_RS07520	COG0653	protein targeting
B9C57_RS07525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B9C57_RS07535	COG1620	l-lactate permease
B9C57_RS07540	COG1304	FMN binding
B9C57_RS07545	COG1193	negative regulation of DNA recombination
B9C57_RS07550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B9C57_RS07555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B9C57_RS07560	COG0504	CTP synthase activity
B9C57_RS07565	COG0706	membrane insertase activity
B9C57_RS07580	COG0590	tRNA wobble adenosine to inosine editing
B9C57_RS07615	COG1012	belongs to the aldehyde dehydrogenase family
B9C57_RS07625	COG0473	3-isopropylmalate dehydrogenase activity
B9C57_RS07630	COG0066	3-isopropylmalate dehydratase activity
B9C57_RS07635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B9C57_RS07640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B9C57_RS07665	COG1607	acyl-coa hydrolase
B9C57_RS07805	COG1090	epimerase
B9C57_RS07815	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9C57_RS07865	COG0156	8-amino-7-oxononanoate synthase activity
B9C57_RS07870	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B9C57_RS07880	COG3781	membrane
B9C57_RS07890	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B9C57_RS07895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B9C57_RS07900	COG1702	phosphate starvation-inducible protein PhoH
B9C57_RS07905	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
B9C57_RS07995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B9C57_RS08000	COG1573	uracil-dna glycosylase
B9C57_RS08045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B9C57_RS08070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B9C57_RS08075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B9C57_RS08090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS08135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B9C57_RS08150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B9C57_RS08170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9C57_RS08225	COG0482	sulfurtransferase activity
B9C57_RS08250	COG0018	arginyl-trna synthetase
B9C57_RS08255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B9C57_RS08345	COG0564	pseudouridine synthase activity
B9C57_RS08355	COG1181	Belongs to the D-alanine--D-alanine ligase family
B9C57_RS08360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B9C57_RS08390	COG1902	pentaerythritol trinitrate reductase activity
B9C57_RS08395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9C57_RS08395	COG2207	Transcriptional regulator
B9C57_RS08405	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
B9C57_RS08410	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B9C57_RS08420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9C57_RS08440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B9C57_RS08445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B9C57_RS08450	COG5492	domain, Protein
B9C57_RS08455	COG1595	DNA-templated transcription, initiation
B9C57_RS08460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B9C57_RS08465	COG0408	coproporphyrinogen oxidase activity
B9C57_RS08480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B9C57_RS08485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B9C57_RS08490	COG0113	porphobilinogen synthase activity
B9C57_RS08495	COG0181	hydroxymethylbilane synthase activity
B9C57_RS08500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B9C57_RS08515	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B9C57_RS08520	COG1981	membrane
B9C57_RS08525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B9C57_RS08525	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
B9C57_RS08545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B9C57_RS08550	COG2195	Cleaves the N-terminal amino acid of tripeptides
B9C57_RS08555	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
B9C57_RS08560	COG0405	Gamma-glutamyltransferase
B9C57_RS08565	COG0564	pseudouridine synthase activity
B9C57_RS08590	COG0336	Belongs to the RNA methyltransferase TrmD family
B9C57_RS08595	COG0335	large ribosomal subunit rRNA binding
B9C57_RS08605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B9C57_RS08630	COG0823	Involved in the tonB-independent uptake of proteins
B9C57_RS08640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B9C57_RS08650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B9C57_RS08665	COG3279	Response regulator of the LytR AlgR family
B9C57_RS08670	COG3275	phosphorelay sensor kinase activity
B9C57_RS08675	COG5002	protein histidine kinase activity
B9C57_RS08675	COG3850	Histidine kinase
B9C57_RS08680	COG0745	RESPONSE REGULATOR receiver
B9C57_RS08730	COG1741	Belongs to the pirin family
B9C57_RS08760	COG0494	nUDIX hydrolase
B9C57_RS08775	COG1073	alpha beta
B9C57_RS08795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B9C57_RS08805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B9C57_RS08815	COG0217	transcriptional regulatory protein
B9C57_RS08845	COG0183	Belongs to the thiolase family
B9C57_RS08850	COG0791	NLP P60 protein
B9C57_RS08865	COG0542	response to heat
B9C57_RS08880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B9C57_RS08885	COG0545	Peptidyl-prolyl cis-trans isomerase
B9C57_RS08895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B9C57_RS08900	COG0105	UTP biosynthetic process
B9C57_RS08920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B9C57_RS08925	COG0457	Tetratricopeptide repeat
B9C57_RS08925	COG1477	protein flavinylation
B9C57_RS08930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B9C57_RS08940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B9C57_RS08960	COG1522	sequence-specific DNA binding
B9C57_RS08965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B9C57_RS08970	COG0747	negative chemotaxis
B9C57_RS08975	COG3015	lipoprotein NlpE involved in copper resistance
B9C57_RS08980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9C57_RS09000	COG4895	conserved protein (DUF2196)
B9C57_RS09005	COG1278	Cold shock
B9C57_RS09010	COG0302	gtp cyclohydrolase
B9C57_RS09015	COG0124	histidyl-tRNA synthetase
B9C57_RS09020	COG1295	ribonuclease BN
B9C57_RS09030	COG0339	signal peptide processing
B9C57_RS09040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B9C57_RS09060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B9C57_RS09065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B9C57_RS09070	COG1120	ATPase activity
B9C57_RS09075	COG2234	aminopeptidase activity
B9C57_RS09105	COG0488	(ABC) transporter
B9C57_RS09150	COG2197	response regulator
B9C57_RS09160	COG2197	response regulator
B9C57_RS09165	COG0494	nUDIX hydrolase
B9C57_RS09175	COG0009	L-threonylcarbamoyladenylate synthase
B9C57_RS09205	COG1132	(ABC) transporter
B9C57_RS09215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B9C57_RS09225	COG1862	Preprotein translocase
B9C57_RS09235	COG0237	dephospho-CoA kinase activity
B9C57_RS09250	COG1131	(ABC) transporter
B9C57_RS09265	COG0556	nucleotide-excision repair
B9C57_RS09270	COG0045	succinate-CoA ligase (ADP-forming) activity
B9C57_RS09365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B9C57_RS09380	COG1366	Belongs to the anti-sigma-factor antagonist family
B9C57_RS09390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B9C57_RS09395	COG0552	protein localization to endoplasmic reticulum
B9C57_RS09405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B9C57_RS09410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B9C57_RS09415	COG1058	Belongs to the CinA family
B9C57_RS09415	COG1546	Belongs to the CinA family
B9C57_RS09435	COG2996	Protein conserved in bacteria
B9C57_RS09440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B9C57_RS09445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B9C57_RS09450	COG0300	oxidoreductase activity
B9C57_RS09455	COG0259	pyridoxamine-phosphate oxidase activity
B9C57_RS09470	COG2885	chlorophyll binding
B9C57_RS09470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B9C57_RS09500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B9C57_RS09510	COG2339	peptidase activity
B9C57_RS09520	COG0010	Belongs to the arginase family
B9C57_RS09530	COG0148	phosphopyruvate hydratase activity
B9C57_RS09550	COG0505	Belongs to the CarA family
B9C57_RS09560	COG0203	ribosomal protein L17
B9C57_RS09565	COG0202	RNA polymerase activity
B9C57_RS09570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B9C57_RS09575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B9C57_RS09580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B9C57_RS09585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B9C57_RS09590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B9C57_RS09600	COG0200	Binds to the 23S rRNA
B9C57_RS09605	COG1841	ribosomal large subunit assembly
B9C57_RS09610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B9C57_RS09615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B9C57_RS09620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B9C57_RS09625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B9C57_RS09630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B9C57_RS09635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B9C57_RS09640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B9C57_RS09645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B9C57_RS09650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B9C57_RS09655	COG0255	Belongs to the universal ribosomal protein uL29 family
B9C57_RS09660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B9C57_RS09665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B9C57_RS09670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B9C57_RS09675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B9C57_RS09680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B9C57_RS09685	COG0089	rRNA binding
B9C57_RS09690	COG0088	Forms part of the polypeptide exit tunnel
B9C57_RS09695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B9C57_RS09700	COG0051	transcription antitermination factor activity, RNA binding
B9C57_RS09705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B9C57_RS09710	COG0049	tRNA binding
B9C57_RS09715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B9C57_RS09725	COG1629	transport
B9C57_RS09745	COG1629	transport
B9C57_RS09760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9C57_RS09770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B9C57_RS09790	COG1011	Hydrolase
B9C57_RS09815	COG2003	Belongs to the UPF0758 family
B9C57_RS09820	COG0569	domain protein
B9C57_RS09825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B9C57_RS09845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B9C57_RS09850	COG2373	Large extracellular alpha-helical protein
B9C57_RS09865	COG1404	Belongs to the peptidase S8 family
B9C57_RS09875	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B9C57_RS09885	COG0753	catalase activity
B9C57_RS09890	COG0583	DNA-binding transcription factor activity
B9C57_RS09895	COG3530	Putative quorum-sensing-regulated virulence factor
B9C57_RS10010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B9C57_RS10090	COG1715	Restriction endonuclease
B9C57_RS10115	COG0671	phosphoesterase, PA-phosphatase related
B9C57_RS10120	COG2194	sulfuric ester hydrolase activity
B9C57_RS10160	COG3179	chitinase
B9C57_RS10190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B9C57_RS10195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B9C57_RS10205	COG0174	glutamine synthetase
B9C57_RS10245	COG1858	cytochrome C peroxidase
B9C57_RS10275	COG2264	protein methyltransferase activity
B9C57_RS10280	COG0149	triose-phosphate isomerase activity
B9C57_RS10285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS10295	COG0601	transmembrane transport
B9C57_RS10300	COG0284	orotidine-5'-phosphate decarboxylase activity
B9C57_RS10310	COG1629	transport
B9C57_RS10315	COG3279	Response regulator of the LytR AlgR family
B9C57_RS10320	COG3275	phosphorelay sensor kinase activity
B9C57_RS10340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B9C57_RS10370	COG1703	isobutyryl-CoA mutase activity
B9C57_RS10370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS10370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B9C57_RS10390	COG4946	Tricorn protease homolog
B9C57_RS10390	COG0793	Belongs to the peptidase S41A family
B9C57_RS10400	COG0159	tryptophan synthase activity
B9C57_RS10405	COG0133	tryptophan synthase activity
B9C57_RS10410	COG0135	phosphoribosylanthranilate isomerase activity
B9C57_RS10415	COG0134	indole-3-glycerol-phosphate synthase activity
B9C57_RS10420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9C57_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
B9C57_RS10425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B9C57_RS10430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B9C57_RS10435	COG0367	asparagine synthase
B9C57_RS10450	COG0187	DNA topoisomerase II activity
B9C57_RS10475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9C57_RS10480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9C57_RS10515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B9C57_RS10520	COG2089	acid synthase
B9C57_RS10535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B9C57_RS10540	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
B9C57_RS10545	COG0667	Aldo Keto reductase
B9C57_RS10550	COG1086	Polysaccharide biosynthesis protein
B9C57_RS10575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B9C57_RS10590	COG0285	dihydrofolate synthase activity
B9C57_RS10600	COG0848	biopolymer transport protein
B9C57_RS10605	COG0811	peptide transport
B9C57_RS10610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B9C57_RS10625	COG1960	acyl-CoA dehydrogenase activity
B9C57_RS10630	COG0101	tRNA pseudouridine synthase activity
B9C57_RS10635	COG0067	glutamate synthase
B9C57_RS10635	COG0069	glutamate synthase activity
B9C57_RS10635	COG0070	glutamate synthase
B9C57_RS10645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B9C57_RS10710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B9C57_RS10715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B9C57_RS10720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B9C57_RS10725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B9C57_RS10735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B9C57_RS10740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B9C57_RS10745	COG0563	adenylate kinase activity
B9C57_RS10750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B9C57_RS10760	COG0791	NLP P60 protein
B9C57_RS10765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9C57_RS10775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B9C57_RS10780	COG0793	Belongs to the peptidase S41A family
B9C57_RS10795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B9C57_RS10800	COG0658	competence protein
B9C57_RS10800	COG2333	competence protein COMEC
B9C57_RS10805	COG4232	protein-disulfide reductase activity
B9C57_RS10815	COG3104	oligopeptide transport
B9C57_RS10820	COG0823	Involved in the tonB-independent uptake of proteins
B9C57_RS10820	COG1506	peptidase
B9C57_RS10835	COG2081	HI0933 family
B9C57_RS10865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B9C57_RS10875	COG0527	aspartate kinase activity
B9C57_RS10875	COG0460	homoserine dehydrogenase
B9C57_RS10880	COG0626	cystathionine gamma-synthase activity
B9C57_RS10885	COG1959	2 iron, 2 sulfur cluster binding
B9C57_RS10895	COG0175	sulfate reduction
B9C57_RS10900	COG0175	sulfate reduction
B9C57_RS10910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B9C57_RS10925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B9C57_RS10925	COG1648	precorrin-2 dehydrogenase activity
B9C57_RS10930	COG0492	ferredoxin-NADP+ reductase activity
B9C57_RS10940	COG1045	serine acetyltransferase
B9C57_RS10950	COG0646	methionine synthase
B9C57_RS10950	COG1410	methionine synthase
B9C57_RS10960	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B9C57_RS11005	COG0436	Aminotransferase
B9C57_RS11010	COG0287	Prephenate dehydrogenase
B9C57_RS11015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B9C57_RS11020	COG1162	GTPase activity
B9C57_RS11025	COG1490	D-aminoacyl-tRNA deacylase activity
B9C57_RS11035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B9C57_RS11060	COG0321	lipoyl(octanoyl) transferase activity
B9C57_RS11070	COG1428	Deoxynucleoside kinase
B9C57_RS11075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B9C57_RS11085	COG0191	fructose-bisphosphate aldolase activity
B9C57_RS11090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B9C57_RS11095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B9C57_RS11100	COG1185	polyribonucleotide nucleotidyltransferase activity
B9C57_RS11105	COG1428	Deoxynucleoside kinase
B9C57_RS11120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B9C57_RS11125	COG0358	DNA primase activity
B9C57_RS11135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B9C57_RS11145	COG0544	peptidyl-prolyl cis-trans isomerase activity
B9C57_RS11150	COG1950	PFAM Membrane protein of
B9C57_RS11180	COG0596	Alpha beta hydrolase
B9C57_RS11185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B9C57_RS11195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B9C57_RS11205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B9C57_RS11225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B9C57_RS11250	COG4771	TonB-dependent receptor
B9C57_RS11255	COG0702	epimerase
B9C57_RS11265	COG2186	Transcriptional regulator
B9C57_RS11275	COG2755	lipolytic protein G-D-S-L family
B9C57_RS11290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B9C57_RS11300	COG0363	glucosamine-6-phosphate deaminase activity
B9C57_RS11310	COG3501	Rhs element vgr protein
B9C57_RS11330	COG3209	COG3209 Rhs family protein
B9C57_RS11340	COG3209	COG3209 Rhs family protein
B9C57_RS11360	COG4104	PAAR repeat-containing protein
B9C57_RS11360	COG3209	COG3209 Rhs family protein
B9C57_RS11380	COG3209	COG3209 Rhs family protein
B9C57_RS11390	COG3209	COG3209 Rhs family protein
B9C57_RS11410	COG1408	metallophosphoesterase
B9C57_RS11415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9C57_RS11415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B9C57_RS11425	COG0513	Belongs to the DEAD box helicase family
B9C57_RS11450	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B9C57_RS11455	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B9C57_RS11460	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B9C57_RS11465	COG1805	sodium ion transport
B9C57_RS11480	COG2967	ApaG domain
B9C57_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
B9C57_RS11500	COG0513	Belongs to the DEAD box helicase family
B9C57_RS11505	COG4977	sequence-specific DNA binding
B9C57_RS11520	COG0357	Ribosomal RNA small subunit methyltransferase G
B9C57_RS11525	COG3239	Fatty acid desaturase
B9C57_RS11530	COG0436	Aminotransferase
B9C57_RS11540	COG0084	hydrolase, TatD family'
B9C57_RS11555	COG2258	MOSC domain
B9C57_RS11560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B9C57_RS11565	COG0714	Associated with various cellular activities
B9C57_RS11585	COG2304	oxidoreductase activity
B9C57_RS11610	COG0659	secondary active sulfate transmembrane transporter activity
B9C57_RS11645	COG0792	nuclease activity
B9C57_RS11650	COG1619	proteins homologs of microcin C7 resistance protein MccF
B9C57_RS11655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9C57_RS11655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B9C57_RS11660	COG2183	response to ionizing radiation
B9C57_RS11670	COG0596	Alpha beta hydrolase
B9C57_RS11705	COG1757	Na H antiporter
B9C57_RS11715	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B9C57_RS11730	COG2824	Alkylphosphonate utilization operon protein PhnA
B9C57_RS11735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B9C57_RS11740	COG0228	four-way junction DNA binding
B9C57_RS11745	COG1278	Cold shock
B9C57_RS11785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B9C57_RS11790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B9C57_RS11795	COG0606	chelatase, subunit chli
B9C57_RS11810	COG4232	protein-disulfide reductase activity
B9C57_RS11815	COG0037	tRNA processing
B9C57_RS11820	COG0596	Alpha beta hydrolase
B9C57_RS11835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B9C57_RS11845	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9C57_RS11845	COG0022	dehydrogenase e1 component
B9C57_RS11855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B9C57_RS11865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B9C57_RS11870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B9C57_RS11875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B9C57_RS11890	COG1054	Belongs to the UPF0176 family
B9C57_RS11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9C57_RS11895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B9C57_RS11905	COG2255	four-way junction helicase activity
B9C57_RS11910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B9C57_RS11915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B9C57_RS11940	COG0437	4 iron, 4 sulfur cluster binding
B9C57_RS11955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B9C57_RS11960	COG2251	uridine kinase activity
B9C57_RS11960	COG0195	Participates in both transcription termination and antitermination
B9C57_RS11965	COG0779	Required for maturation of 30S ribosomal subunits
B9C57_RS11995	COG4771	TonB-dependent receptor
B9C57_RS12025	COG1054	Belongs to the UPF0176 family
B9C57_RS12045	COG2226	methyltransferase
B9C57_RS12050	COG0306	phosphate transporter
B9C57_RS12100	COG4717	serine-type aminopeptidase activity
B9C57_RS12110	COG0589	response to stress
B9C57_RS12125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B9C57_RS12145	COG1215	transferase activity, transferring glycosyl groups
B9C57_RS12155	COG1609	Transcriptional regulator
B9C57_RS12185	COG0509	glycine decarboxylation via glycine cleavage system
B9C57_RS12195	COG0632	four-way junction helicase activity
B9C57_RS12200	COG0281	malic enzyme
B9C57_RS12200	COG0280	phosphate acetyltransferase
B9C57_RS12205	COG0840	transmembrane signaling receptor activity
B9C57_RS12210	COG0840	transmembrane signaling receptor activity
B9C57_RS12220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B9C57_RS12235	COG2814	Major facilitator Superfamily
B9C57_RS12245	COG1381	Involved in DNA repair and RecF pathway recombination
B9C57_RS12255	COG2954	triphosphatase activity
B9C57_RS12260	COG3275	phosphorelay sensor kinase activity
B9C57_RS12265	COG3279	Response regulator of the LytR AlgR family
B9C57_RS12270	COG1272	protein, Hemolysin III
B9C57_RS12290	COG1970	mechanosensitive ion channel activity
B9C57_RS12295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B9C57_RS12300	COG1435	thymidine kinase activity
B9C57_RS12330	COG0626	cystathionine gamma-synthase activity
B9C57_RS12340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B9C57_RS12340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B9C57_RS12355	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B9C57_RS12375	COG1074	ATP-dependent DNA helicase activity
B9C57_RS12380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9C57_RS12385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B9C57_RS12390	COG1121	(ABC) transporter
B9C57_RS12395	COG0803	Belongs to the bacterial solute-binding protein 9 family
B9C57_RS12405	COG4771	TonB-dependent receptor
B9C57_RS12450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B9C57_RS12455	COG1053	succinate dehydrogenase
B9C57_RS12485	COG0463	Glycosyl transferase, family 2
B9C57_RS12490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B9C57_RS12500	COG0702	epimerase
B9C57_RS12510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B9C57_RS12520	COG4771	TonB-dependent receptor
B9C57_RS12535	COG0495	leucyl-tRNA aminoacylation
B9C57_RS12550	COG1946	Acyl-CoA thioesterase
B9C57_RS12570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B9C57_RS12575	COG0194	GDP metabolic process
B9C57_RS12580	COG1561	YicC-like family, N-terminal region
B9C57_RS12590	COG1652	LysM domain
B9C57_RS12600	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B9C57_RS12620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B9C57_RS12625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B9C57_RS12635	COG5658	integral membrane protein
B9C57_RS12640	COG1999	signal sequence binding
B9C57_RS12660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B9C57_RS12665	COG2268	Band 7 protein
B9C57_RS12680	COG1012	belongs to the aldehyde dehydrogenase family
B9C57_RS12720	COG0508	dehydrogenase complex catalyzes the overall conversion of
B9C57_RS12730	COG0719	Fe-S assembly protein
B9C57_RS12735	COG0396	ATPase activity
B9C57_RS12740	COG0719	Fe-S assembly protein
B9C57_RS12750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B9C57_RS12765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9C57_RS12770	COG0671	phosphoesterase, PA-phosphatase related
B9C57_RS12785	COG1595	DNA-templated transcription, initiation
B9C57_RS12790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B9C57_RS12795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B9C57_RS12860	COG0667	Aldo Keto reductase
B9C57_RS12865	COG0126	phosphoglycerate kinase activity
B9C57_RS12870	COG0314	molybdopterin synthase activity
B9C57_RS12895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B9C57_RS12905	COG0527	aspartate kinase activity
B9C57_RS12920	COG2095	MarC family integral membrane protein
B9C57_RS12930	COG1404	Belongs to the peptidase S8 family
B9C57_RS12935	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B9C57_RS12940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B9C57_RS12940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B9C57_RS12955	COG1505	serine-type exopeptidase activity
B9C57_RS12960	COG3590	peptidase
B9C57_RS12970	COG0189	ligase activity
B9C57_RS12975	COG3842	ATPase activity
B9C57_RS13000	COG4221	oxidoreductase activity
B9C57_RS13045	COG1607	acyl-coa hydrolase
B9C57_RS13055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B9C57_RS13055	COG0758	DNA mediated transformation
B9C57_RS13080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B9C57_RS13090	COG0594	ribonuclease P activity
B9C57_RS13095	COG0793	Belongs to the peptidase S41A family
B9C57_RS13110	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B9C57_RS13125	COG2244	polysaccharide biosynthetic process
B9C57_RS13130	COG1216	Glycosyl transferase, family 2
B9C57_RS13160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B9C57_RS13170	COG0151	Belongs to the GarS family
B9C57_RS13175	COG5002	protein histidine kinase activity
B9C57_RS13180	COG0745	RESPONSE REGULATOR receiver
B9C57_RS13195	COG0488	(ABC) transporter
B9C57_RS13205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B9C57_RS13225	COG0527	aspartate kinase activity
B9C57_RS13230	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B9C57_RS13235	COG0534	Mate efflux family protein
B9C57_RS13240	COG0756	dUTP diphosphatase activity
B9C57_RS13245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B9C57_RS13250	COG1187	pseudouridine synthase activity
B9C57_RS13255	COG2153	protein acetylation
B9C57_RS13260	COG0698	ribose 5-phosphate isomerase
B9C57_RS13270	COG1597	lipid kinase activity
B9C57_RS13275	COG0557	exoribonuclease II activity
B9C57_RS13295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B9C57_RS13300	COG0330	HflC and HflK could
B9C57_RS13320	COG0445	tRNA wobble uridine modification
B9C57_RS13325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B9C57_RS13345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B9C57_RS13350	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B9C57_RS13365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9C57_RS13495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B9C57_RS13505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B9C57_RS13525	COG0720	synthase
B9C57_RS13535	COG0193	aminoacyl-tRNA hydrolase activity
B9C57_RS13540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B9C57_RS13545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B9C57_RS13665	COG1404	Belongs to the peptidase S8 family
B9C57_RS13705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B9C57_RS13715	COG0746	molybdenum cofactor guanylyltransferase activity
B9C57_RS13715	COG0315	cyclic pyranopterin monophosphate synthase activity
B9C57_RS13720	COG0315	cyclic pyranopterin monophosphate synthase activity
B9C57_RS13725	COG0303	'Molybdopterin
B9C57_RS13730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B9C57_RS13735	COG0322	excinuclease ABC activity
B9C57_RS13745	COG1530	ribonuclease E activity
B9C57_RS13760	COG0629	single-stranded DNA binding
B9C57_RS13790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B9C57_RS13795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B9C57_RS13805	COG3279	Response regulator of the LytR AlgR family
B9C57_RS13810	COG2972	Histidine kinase
B9C57_RS13810	COG0745	RESPONSE REGULATOR receiver
B9C57_RS13835	COG0826	peptidase U32
B9C57_RS13845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B9C57_RS13850	COG1418	mRNA catabolic process
B9C57_RS13860	COG1024	Enoyl-CoA hydratase
B9C57_RS13865	COG5000	phosphorelay sensor kinase activity
B9C57_RS13870	COG0470	DNA polymerase III
B9C57_RS13935	COG2267	carboxylic ester hydrolase activity
B9C57_RS13940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B9C57_RS13955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B9C57_RS13970	COG0489	protein tyrosine kinase activity
B9C57_RS13980	COG0492	ferredoxin-NADP+ reductase activity
B9C57_RS13990	COG0633	Ferredoxin
B9C57_RS13995	COG0716	FMN binding
B9C57_RS14000	COG0076	glutamate decarboxylase activity
B9C57_RS14005	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B9C57_RS14040	COG0657	acetylesterase activity
B9C57_RS14050	COG2207	Transcriptional regulator
B9C57_RS14050	COG1609	Transcriptional regulator
B9C57_RS14080	COG4774	siderophore transport
B9C57_RS14090	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B9C57_RS14095	COG3483	tryptophan 2,3-dioxygenase activity
B9C57_RS14110	COG0166	Belongs to the GPI family
B9C57_RS14115	COG4771	TonB-dependent receptor
B9C57_RS14140	COG0006	proline dipeptidase activity
B9C57_RS14145	COG0513	Belongs to the DEAD box helicase family
B9C57_RS14170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B9C57_RS14185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B9C57_RS14195	COG1040	competence protein
B9C57_RS14200	COG3963	phosphatidate phosphatase activity
B9C57_RS14215	COG0423	glycine-tRNA ligase activity
B9C57_RS14230	COG1629	transport
B9C57_RS14235	COG0196	riboflavin kinase activity
B9C57_RS14245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B9C57_RS14260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B9C57_RS14265	COG2239	Acts as a magnesium transporter
B9C57_RS14290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B9C57_RS14305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B9C57_RS14310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B9C57_RS14315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9C57_RS14320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B9C57_RS14325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B9C57_RS14330	COG0356	it plays a direct role in the translocation of protons across the membrane
B9C57_RS14365	COG0708	Exodeoxyribonuclease III
B9C57_RS14375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B9C57_RS14380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B9C57_RS14390	COG1774	PSP1 C-terminal conserved region
B9C57_RS14405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B9C57_RS14415	COG1115	amino acid carrier protein
B9C57_RS14425	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B9C57_RS14435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B9C57_RS14445	COG0584	glycerophosphoryl diester phosphodiesterase
B9C57_RS14450	COG1288	antiporter activity
B9C57_RS14455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B9C57_RS14465	COG2166	iron-sulfur cluster assembly
B9C57_RS14470	COG2151	metal-sulfur cluster biosynthetic enzyme
B9C57_RS14490	COG1253	flavin adenine dinucleotide binding
B9C57_RS14520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B9C57_RS14530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B9C57_RS14540	COG0297	glycogen (starch) synthase activity
B9C57_RS14545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B9C57_RS14550	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B9C57_RS14560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B9C57_RS14565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B9C57_RS14590	COG4942	peptidase