locus-tag	class	description
F9Y86_RS00010	COG0463	Glycosyl transferase, family 2
F9Y86_RS00025	COG4974	Belongs to the 'phage' integrase family
F9Y86_RS00055	COG1183	phosphatidylcholine synthase activity
F9Y86_RS00070	COG0805	protein transport
F9Y86_RS00075	COG0517	IMP dehydrogenase activity
F9Y86_RS00075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9Y86_RS00080	COG0514	ATP-dependent DNA helicase (RecQ)
F9Y86_RS00100	COG0686	Belongs to the AlaDH PNT family
F9Y86_RS00105	COG0802	atpase or kinase
F9Y86_RS00110	COG2204	response regulator
F9Y86_RS00115	COG1078	dGTPase activity
F9Y86_RS00120	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9Y86_RS00125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F9Y86_RS00125	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F9Y86_RS00130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9Y86_RS00135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F9Y86_RS00145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F9Y86_RS00150	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS00205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F9Y86_RS00210	COG1690	Belongs to the RtcB family
F9Y86_RS00240	COG0300	oxidoreductase activity
F9Y86_RS00255	COG1741	Belongs to the pirin family
F9Y86_RS00295	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F9Y86_RS00305	COG1061	Type III restriction enzyme res subunit
F9Y86_RS00315	COG0542	response to heat
F9Y86_RS00325	COG3047	cAMP biosynthetic process
F9Y86_RS00330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F9Y86_RS00340	COG0424	maF-like protein
F9Y86_RS00345	COG3958	Transketolase
F9Y86_RS00355	COG0545	Peptidyl-prolyl cis-trans isomerase
F9Y86_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9Y86_RS00365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
F9Y86_RS00370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F9Y86_RS00390	COG0590	tRNA wobble adenosine to inosine editing
F9Y86_RS00415	COG2814	Major facilitator Superfamily
F9Y86_RS00425	COG1522	sequence-specific DNA binding
F9Y86_RS00445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9Y86_RS00460	COG1739	Uncharacterized protein family UPF0029
F9Y86_RS00465	COG0697	spore germination
F9Y86_RS00470	COG1011	Hydrolase
F9Y86_RS00475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9Y86_RS00475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9Y86_RS00490	COG2890	protein-(glutamine-N5) methyltransferase activity
F9Y86_RS00535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9Y86_RS00550	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F9Y86_RS00555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9Y86_RS00560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9Y86_RS00560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9Y86_RS00600	COG0012	GTP binding
F9Y86_RS00605	COG4206	TonB-dependent receptor
F9Y86_RS00605	COG1629	transport
F9Y86_RS00610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9Y86_RS00620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F9Y86_RS00625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9Y86_RS00635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F9Y86_RS00640	COG0322	excinuclease ABC activity
F9Y86_RS00645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9Y86_RS00650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F9Y86_RS00665	COG1217	gtp-binding protein TYPA
F9Y86_RS00680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F9Y86_RS00685	COG1196	nuclear chromosome segregation
F9Y86_RS00685	COG3264	Mechanosensitive ion channel
F9Y86_RS00690	COG0783	Belongs to the Dps family
F9Y86_RS00720	COG0438	transferase activity, transferring glycosyl groups
F9Y86_RS00725	COG3959	Transketolase, thiamine diphosphate binding domain
F9Y86_RS00765	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9Y86_RS00780	COG0359	binds to the 23S rRNA
F9Y86_RS00785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F9Y86_RS00790	COG0360	Binds together with S18 to 16S ribosomal RNA
F9Y86_RS00820	COG0140	phosphoribosyl-ATP diphosphatase activity
F9Y86_RS00820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9Y86_RS00825	COG0107	imidazoleglycerol-phosphate synthase activity
F9Y86_RS00830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F9Y86_RS00840	COG0131	Imidazoleglycerol-phosphate dehydratase
F9Y86_RS00845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9Y86_RS00850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9Y86_RS00855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F9Y86_RS00875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9Y86_RS00885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9Y86_RS00910	COG0076	glutamate decarboxylase activity
F9Y86_RS00920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9Y86_RS00930	COG3547	Transposase (IS116 IS110 IS902 family)
F9Y86_RS00935	COG1204	response to ionizing radiation
F9Y86_RS00975	COG0527	aspartate kinase activity
F9Y86_RS00975	COG0460	homoserine dehydrogenase
F9Y86_RS00980	COG0083	homoserine kinase activity
F9Y86_RS00985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9Y86_RS00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9Y86_RS01000	COG3275	phosphorelay sensor kinase activity
F9Y86_RS01005	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS01020	COG0564	pseudouridine synthase activity
F9Y86_RS01025	COG2270	Major facilitator Superfamily
F9Y86_RS01050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9Y86_RS01055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F9Y86_RS01090	COG2003	Belongs to the UPF0758 family
F9Y86_RS01095	COG3340	Belongs to the peptidase S51 family
F9Y86_RS01165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F9Y86_RS01180	COG0167	dihydroorotate dehydrogenase activity
F9Y86_RS01210	COG1363	Peptidase, m42
F9Y86_RS01270	COG0488	(ABC) transporter
F9Y86_RS01280	COG0513	Belongs to the DEAD box helicase family
F9Y86_RS01295	COG1045	serine acetyltransferase
F9Y86_RS01300	COG0633	Ferredoxin
F9Y86_RS01305	COG0492	ferredoxin-NADP+ reductase activity
F9Y86_RS01310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9Y86_RS01310	COG1648	precorrin-2 dehydrogenase activity
F9Y86_RS01320	COG1648	precorrin-2 dehydrogenase activity
F9Y86_RS01320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9Y86_RS01330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9Y86_RS01340	COG0175	sulfate reduction
F9Y86_RS01345	COG0175	sulfate reduction
F9Y86_RS01355	COG1959	2 iron, 2 sulfur cluster binding
F9Y86_RS01365	COG0527	aspartate kinase activity
F9Y86_RS01365	COG0460	homoserine dehydrogenase
F9Y86_RS01375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F9Y86_RS01380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9Y86_RS01385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9Y86_RS01390	COG0517	IMP dehydrogenase activity
F9Y86_RS01390	COG0516	GMP reductase activity
F9Y86_RS01410	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS01415	COG2205	protein histidine kinase activity
F9Y86_RS01460	COG1595	DNA-templated transcription, initiation
F9Y86_RS01480	COG0525	valine-tRNA ligase activity
F9Y86_RS01490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9Y86_RS01495	COG0436	Aminotransferase
F9Y86_RS01500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F9Y86_RS01520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9Y86_RS01535	COG3876	Protein conserved in bacteria
F9Y86_RS01560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F9Y86_RS01580	COG0714	Associated with various cellular activities
F9Y86_RS01625	COG0534	Mate efflux family protein
F9Y86_RS01640	COG1131	(ABC) transporter
F9Y86_RS01670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F9Y86_RS01670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9Y86_RS01680	COG0644	oxidoreductase
F9Y86_RS01690	COG0646	methionine synthase
F9Y86_RS01690	COG1410	methionine synthase
F9Y86_RS01695	COG0646	methionine synthase
F9Y86_RS01695	COG1410	methionine synthase
F9Y86_RS01700	COG2986	histidine ammonia-lyase
F9Y86_RS01705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9Y86_RS01785	COG0433	COG0433 Predicted ATPase
F9Y86_RS01790	COG0602	queuosine metabolic process
F9Y86_RS01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9Y86_RS01820	COG0825	malonyl-CoA metabolic process
F9Y86_RS01835	COG0343	queuine tRNA-ribosyltransferase activity
F9Y86_RS01840	COG1187	pseudouridine synthase activity
F9Y86_RS01865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F9Y86_RS01870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9Y86_RS01870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9Y86_RS01885	COG1858	cytochrome C peroxidase
F9Y86_RS01900	COG4585	Histidine kinase
F9Y86_RS01910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9Y86_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
F9Y86_RS01925	COG2207	Transcriptional regulator
F9Y86_RS01935	COG0783	Belongs to the Dps family
F9Y86_RS01950	COG0659	secondary active sulfate transmembrane transporter activity
F9Y86_RS01955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
F9Y86_RS01960	COG0540	Belongs to the ATCase OTCase family
F9Y86_RS01975	COG1234	tRNA 3'-trailer cleavage
F9Y86_RS01995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9Y86_RS02000	COG0326	Molecular chaperone. Has ATPase activity
F9Y86_RS02005	COG0564	pseudouridine synthase activity
F9Y86_RS02010	COG0336	Belongs to the RNA methyltransferase TrmD family
F9Y86_RS02015	COG0335	large ribosomal subunit rRNA binding
F9Y86_RS02070	COG1090	epimerase
F9Y86_RS02075	COG0454	-acetyltransferase
F9Y86_RS02080	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9Y86_RS02085	COG0408	coproporphyrinogen oxidase activity
F9Y86_RS02100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F9Y86_RS02105	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F9Y86_RS02110	COG0113	porphobilinogen synthase activity
F9Y86_RS02130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F9Y86_RS02145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F9Y86_RS02150	COG1981	membrane
F9Y86_RS02160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9Y86_RS02165	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9Y86_RS02170	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
F9Y86_RS02175	COG0405	Gamma-glutamyltransferase
F9Y86_RS02180	COG0793	Belongs to the peptidase S41A family
F9Y86_RS02180	COG4946	Tricorn protease homolog
F9Y86_RS02205	COG2326	polyphosphate kinase activity
F9Y86_RS02215	COG0592	DNA-directed DNA polymerase activity
F9Y86_RS02220	COG1192	Involved in chromosome partitioning
F9Y86_RS02225	COG1475	DNA binding
F9Y86_RS02235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F9Y86_RS02240	COG0681	Belongs to the peptidase S26 family
F9Y86_RS02275	COG2207	Transcriptional regulator
F9Y86_RS02295	COG0456	acetyltransferase
F9Y86_RS02300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9Y86_RS02325	COG1472	Belongs to the glycosyl hydrolase 3 family
F9Y86_RS02340	COG2326	polyphosphate kinase activity
F9Y86_RS02360	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS02385	COG3275	phosphorelay sensor kinase activity
F9Y86_RS02410	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F9Y86_RS02415	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F9Y86_RS02420	COG1393	Belongs to the ArsC family
F9Y86_RS02430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F9Y86_RS02475	COG1418	mRNA catabolic process
F9Y86_RS02515	COG2076	Multidrug Resistance protein
F9Y86_RS02525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F9Y86_RS02530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9Y86_RS02535	COG1120	ATPase activity
F9Y86_RS02540	COG2234	aminopeptidase activity
F9Y86_RS02545	COG0076	glutamate decarboxylase activity
F9Y86_RS02555	COG2813	Specifically methylates the guanine in position
F9Y86_RS02560	COG0069	glutamate synthase activity
F9Y86_RS02565	COG0254	rRNA binding
F9Y86_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS02590	COG3091	SprT-like family
F9Y86_RS02605	COG1663	tetraacyldisaccharide 4'-kinase activity
F9Y86_RS02610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9Y86_RS02625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F9Y86_RS02635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F9Y86_RS02635	COG3608	succinylglutamate desuccinylase aspartoacylase
F9Y86_RS02670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9Y86_RS02745	COG0045	succinate-CoA ligase (ADP-forming) activity
F9Y86_RS02755	COG1136	(ABC) transporter
F9Y86_RS02770	COG1366	Belongs to the anti-sigma-factor antagonist family
F9Y86_RS02770	COG2202	Pas domain
F9Y86_RS02785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9Y86_RS02800	COG0154	amidase activity
F9Y86_RS02805	COG1733	regulation of RNA biosynthetic process
F9Y86_RS02815	COG0552	protein localization to endoplasmic reticulum
F9Y86_RS02825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F9Y86_RS02830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F9Y86_RS02835	COG1058	Belongs to the CinA family
F9Y86_RS02835	COG1546	Belongs to the CinA family
F9Y86_RS02840	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9Y86_RS02855	COG2996	Protein conserved in bacteria
F9Y86_RS02860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
F9Y86_RS02865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F9Y86_RS02870	COG0300	oxidoreductase activity
F9Y86_RS02890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F9Y86_RS02910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F9Y86_RS02930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9Y86_RS02935	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9Y86_RS02990	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F9Y86_RS03000	COG0671	phosphoesterase, PA-phosphatase related
F9Y86_RS03005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9Y86_RS03020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F9Y86_RS03030	COG0105	UTP biosynthetic process
F9Y86_RS03075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F9Y86_RS03085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F9Y86_RS03095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9Y86_RS03160	COG4585	Histidine kinase
F9Y86_RS03180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9Y86_RS03185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F9Y86_RS03190	COG4166	transmembrane transport
F9Y86_RS03200	COG2329	Antibiotic biosynthesis monooxygenase
F9Y86_RS03210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9Y86_RS03230	COG0302	gtp cyclohydrolase
F9Y86_RS03235	COG0124	histidyl-tRNA synthetase
F9Y86_RS03240	COG1295	ribonuclease BN
F9Y86_RS03255	COG0339	signal peptide processing
F9Y86_RS03270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9Y86_RS03275	COG3128	pkhd-type hydroxylase
F9Y86_RS03355	COG1607	acyl-coa hydrolase
F9Y86_RS03385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9Y86_RS03395	COG3547	Transposase (IS116 IS110 IS902 family)
F9Y86_RS03480	COG0732	type I restriction modification DNA specificity domain
F9Y86_RS03520	COG1785	Belongs to the alkaline phosphatase family
F9Y86_RS03525	COG0702	epimerase
F9Y86_RS03530	COG4771	TonB-dependent receptor
F9Y86_RS03535	COG3292	Two component regulator propeller
F9Y86_RS03535	COG2205	protein histidine kinase activity
F9Y86_RS03535	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS03585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F9Y86_RS03595	COG0116	Belongs to the methyltransferase superfamily
F9Y86_RS03610	COG0662	Cupin 2, conserved barrel domain protein
F9Y86_RS03610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F9Y86_RS03625	COG0110	maltose O-acetyltransferase activity
F9Y86_RS03645	COG1846	Transcriptional regulator
F9Y86_RS03650	COG1764	response to oxidative stress
F9Y86_RS03660	COG0640	Transcriptional regulator
F9Y86_RS03685	COG0259	pyridoxamine-phosphate oxidase activity
F9Y86_RS03735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9Y86_RS03765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9Y86_RS03810	COG0589	response to stress
F9Y86_RS03830	COG0348	domain, Protein
F9Y86_RS03835	COG2010	Cytochrome c
F9Y86_RS03845	COG3278	Belongs to the heme-copper respiratory oxidase family
F9Y86_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9Y86_RS03860	COG0813	purine-nucleoside phosphorylase activity
F9Y86_RS03865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F9Y86_RS03885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F9Y86_RS03890	COG0085	RNA polymerase activity
F9Y86_RS03895	COG0222	ribosome binding
F9Y86_RS03900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F9Y86_RS03905	COG0081	regulation of translation
F9Y86_RS03910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F9Y86_RS03930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F9Y86_RS03965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9Y86_RS03970	COG1960	acyl-CoA dehydrogenase activity
F9Y86_RS03980	COG1115	amino acid carrier protein
F9Y86_RS03990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9Y86_RS04050	COG1611	Belongs to the LOG family
F9Y86_RS04075	COG0778	Nitroreductase
F9Y86_RS04080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9Y86_RS04090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9Y86_RS04095	COG1280	lysine exporter protein (LysE YggA)
F9Y86_RS04100	COG0583	DNA-binding transcription factor activity
F9Y86_RS04115	COG0450	alkyl hydroperoxide reductase
F9Y86_RS04120	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F9Y86_RS04145	COG2204	response regulator
F9Y86_RS04150	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F9Y86_RS04150	COG3264	Mechanosensitive ion channel
F9Y86_RS04155	COG1668	transmembrane transport
F9Y86_RS04160	COG4152	abc transporter atp-binding protein
F9Y86_RS04170	COG1024	Enoyl-CoA hydratase
F9Y86_RS04170	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9Y86_RS04175	COG0183	Belongs to the thiolase family
F9Y86_RS04185	COG1960	acyl-CoA dehydrogenase activity
F9Y86_RS04220	COG3547	Transposase (IS116 IS110 IS902 family)
F9Y86_RS04255	COG0492	ferredoxin-NADP+ reductase activity
F9Y86_RS04320	COG2207	Transcriptional regulator
F9Y86_RS04400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9Y86_RS04410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9Y86_RS04415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9Y86_RS04420	COG2204	response regulator
F9Y86_RS04425	COG4191	Histidine kinase
F9Y86_RS04445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9Y86_RS04460	COG2197	response regulator
F9Y86_RS04480	COG0101	tRNA pseudouridine synthase activity
F9Y86_RS04485	COG1132	(ABC) transporter
F9Y86_RS04495	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F9Y86_RS04500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9Y86_RS04515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F9Y86_RS04545	COG0572	uridine kinase
F9Y86_RS04555	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9Y86_RS04565	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9Y86_RS04565	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9Y86_RS04570	COG0688	phosphatidylethanolamine metabolic process
F9Y86_RS04575	COG1333	cytochrome c biogenesis protein
F9Y86_RS04575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F9Y86_RS04590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9Y86_RS04595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F9Y86_RS04605	COG0295	cytidine deaminase activity
F9Y86_RS04615	COG0519	Catalyzes the synthesis of GMP from XMP
F9Y86_RS04615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9Y86_RS04620	COG1388	LysM domain
F9Y86_RS04620	COG0860	N-Acetylmuramoyl-L-alanine amidase
F9Y86_RS04635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F9Y86_RS04640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F9Y86_RS04650	COG0438	transferase activity, transferring glycosyl groups
F9Y86_RS04695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F9Y86_RS04720	COG0285	dihydrofolate synthase activity
F9Y86_RS04735	COG0848	biopolymer transport protein
F9Y86_RS04740	COG0811	peptide transport
F9Y86_RS04755	COG1960	acyl-CoA dehydrogenase activity
F9Y86_RS04760	COG0101	tRNA pseudouridine synthase activity
F9Y86_RS04765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9Y86_RS04770	COG0857	belongs to the CobB CobQ family
F9Y86_RS04770	COG0280	phosphate acetyltransferase
F9Y86_RS04835	COG4251	negative regulation of phosphorylation
F9Y86_RS04840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F9Y86_RS04845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F9Y86_RS04850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F9Y86_RS04855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F9Y86_RS04870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F9Y86_RS04875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9Y86_RS04880	COG0563	adenylate kinase activity
F9Y86_RS04885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F9Y86_RS04905	COG4206	TonB-dependent receptor
F9Y86_RS04905	COG1629	transport
F9Y86_RS04920	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS04925	COG0791	NLP P60 protein
F9Y86_RS04930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9Y86_RS04940	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F9Y86_RS04950	COG0793	Belongs to the peptidase S41A family
F9Y86_RS04995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F9Y86_RS05000	COG2333	competence protein COMEC
F9Y86_RS05000	COG0658	competence protein
F9Y86_RS05005	COG4232	protein-disulfide reductase activity
F9Y86_RS05020	COG0823	Involved in the tonB-independent uptake of proteins
F9Y86_RS05020	COG1506	peptidase
F9Y86_RS05035	COG2081	HI0933 family
F9Y86_RS05075	COG1187	pseudouridine synthase activity
F9Y86_RS05235	COG0542	response to heat
F9Y86_RS05265	COG0138	bifunctional purine biosynthesis protein purh
F9Y86_RS05270	COG1077	Cell shape determining protein MreB Mrl
F9Y86_RS05285	COG0768	penicillin binding
F9Y86_RS05290	COG0772	Belongs to the SEDS family
F9Y86_RS05295	COG0268	Binds directly to 16S ribosomal RNA
F9Y86_RS05310	COG0442	prolyl-tRNA aminoacylation
F9Y86_RS05325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F9Y86_RS05330	COG2226	methyltransferase
F9Y86_RS05355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9Y86_RS05360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9Y86_RS05365	COG0517	IMP dehydrogenase activity
F9Y86_RS05375	COG3118	belongs to the thioredoxin family
F9Y86_RS05380	COG1271	oxidase subunit
F9Y86_RS05385	COG1294	oxidase, subunit
F9Y86_RS05410	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS05415	COG3275	phosphorelay sensor kinase activity
F9Y86_RS05445	COG4206	TonB-dependent receptor
F9Y86_RS05445	COG1629	transport
F9Y86_RS05460	COG1610	YqeY-like protein
F9Y86_RS05465	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F9Y86_RS05480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9Y86_RS05485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F9Y86_RS05495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F9Y86_RS05505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F9Y86_RS05510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9Y86_RS05515	COG0768	penicillin binding
F9Y86_RS05525	COG0275	rRNA processing
F9Y86_RS05530	COG2001	Belongs to the MraZ family
F9Y86_RS05540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F9Y86_RS05545	COG0564	pseudouridine synthase activity
F9Y86_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
F9Y86_RS05605	COG0784	Response regulator, receiver
F9Y86_RS05605	COG2198	Histidine kinase
F9Y86_RS05605	COG5002	protein histidine kinase activity
F9Y86_RS05625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F9Y86_RS05635	COG0668	transmembrane transport
F9Y86_RS05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9Y86_RS05670	COG1309	transcriptional regulator
F9Y86_RS05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9Y86_RS05730	COG0612	Peptidase, M16
F9Y86_RS05745	COG4771	TonB-dependent receptor
F9Y86_RS05795	COG1522	sequence-specific DNA binding
F9Y86_RS05800	COG0626	cystathionine gamma-synthase activity
F9Y86_RS05805	COG2095	MarC family integral membrane protein
F9Y86_RS05810	COG1757	Na H antiporter
F9Y86_RS05830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F9Y86_RS05840	COG2824	Alkylphosphonate utilization operon protein PhnA
F9Y86_RS05845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9Y86_RS05850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F9Y86_RS05855	COG0228	four-way junction DNA binding
F9Y86_RS05860	COG1278	Cold shock
F9Y86_RS05925	COG3501	Rhs element vgr protein
F9Y86_RS05960	COG1131	(ABC) transporter
F9Y86_RS05970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F9Y86_RS05980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F9Y86_RS05990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F9Y86_RS06000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F9Y86_RS06005	COG2086	electron transfer activity
F9Y86_RS06010	COG0022	dehydrogenase e1 component
F9Y86_RS06010	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9Y86_RS06015	COG4771	TonB-dependent receptor
F9Y86_RS06020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9Y86_RS06025	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F9Y86_RS06030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F9Y86_RS06040	COG2267	carboxylic ester hydrolase activity
F9Y86_RS06045	COG0037	tRNA processing
F9Y86_RS06050	COG0785	Cytochrome C biogenesis protein
F9Y86_RS06065	COG0606	chelatase, subunit chli
F9Y86_RS06070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9Y86_RS06080	COG1528	Iron-storage protein
F9Y86_RS06085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F9Y86_RS06100	COG3201	nicotinamide mononucleotide transporter
F9Y86_RS06135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9Y86_RS06140	COG0439	Biotin carboxylase
F9Y86_RS06145	COG4770	biotin carboxylase activity
F9Y86_RS06160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F9Y86_RS06165	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F9Y86_RS06170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F9Y86_RS06175	COG1805	sodium ion transport
F9Y86_RS06185	COG1858	cytochrome C peroxidase
F9Y86_RS06205	COG2967	ApaG domain
F9Y86_RS06235	COG1012	belongs to the aldehyde dehydrogenase family
F9Y86_RS06240	COG2131	deaminase
F9Y86_RS06245	COG2066	Belongs to the glutaminase family
F9Y86_RS06255	COG0513	Belongs to the DEAD box helicase family
F9Y86_RS06275	COG0357	Ribosomal RNA small subunit methyltransferase G
F9Y86_RS06280	COG3239	Fatty acid desaturase
F9Y86_RS06285	COG0436	Aminotransferase
F9Y86_RS06295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9Y86_RS06295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F9Y86_RS06305	COG2255	four-way junction helicase activity
F9Y86_RS06310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9Y86_RS06340	COG0437	4 iron, 4 sulfur cluster binding
F9Y86_RS06365	COG2166	iron-sulfur cluster assembly
F9Y86_RS06370	COG2151	metal-sulfur cluster biosynthetic enzyme
F9Y86_RS06390	COG1253	flavin adenine dinucleotide binding
F9Y86_RS06410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9Y86_RS06415	COG1573	uracil-dna glycosylase
F9Y86_RS06425	COG0513	Belongs to the DEAD box helicase family
F9Y86_RS06440	COG0084	hydrolase, TatD family'
F9Y86_RS06450	COG0590	tRNA wobble adenosine to inosine editing
F9Y86_RS06460	COG4771	TonB-dependent receptor
F9Y86_RS06470	COG4771	TonB-dependent receptor
F9Y86_RS06475	COG0714	Associated with various cellular activities
F9Y86_RS06490	COG2304	oxidoreductase activity
F9Y86_RS06495	COG2304	oxidoreductase activity
F9Y86_RS06520	COG0659	secondary active sulfate transmembrane transporter activity
F9Y86_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS06555	COG0792	nuclease activity
F9Y86_RS06565	COG1619	proteins homologs of microcin C7 resistance protein MccF
F9Y86_RS06570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9Y86_RS06570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9Y86_RS06580	COG2183	response to ionizing radiation
F9Y86_RS06595	COG0629	single-stranded DNA binding
F9Y86_RS06610	COG0516	GMP reductase activity
F9Y86_RS06620	COG0469	pyruvate kinase activity
F9Y86_RS06630	COG0571	ribonuclease III activity
F9Y86_RS06635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F9Y86_RS06640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9Y86_RS06645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9Y86_RS06650	COG3341	Caulimovirus viroplasmin
F9Y86_RS06650	COG0328	RNA-DNA hybrid ribonuclease activity
F9Y86_RS06670	COG0668	transmembrane transport
F9Y86_RS06675	COG1214	PFAM Peptidase M22, glycoprotease
F9Y86_RS06690	COG2322	membrane
F9Y86_RS06695	COG1999	signal sequence binding
F9Y86_RS06710	COG1845	cytochrome c oxidase, subunit III
F9Y86_RS06715	COG1845	cytochrome c oxidase, subunit III
F9Y86_RS06720	COG0109	protoheme IX farnesyltransferase activity
F9Y86_RS06760	COG1054	Belongs to the UPF0176 family
F9Y86_RS06775	COG2226	methyltransferase
F9Y86_RS06780	COG1619	proteins homologs of microcin C7 resistance protein MccF
F9Y86_RS06785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9Y86_RS06790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F9Y86_RS06800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F9Y86_RS06805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F9Y86_RS06810	COG0297	glycogen (starch) synthase activity
F9Y86_RS06820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9Y86_RS06840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F9Y86_RS06850	COG1115	amino acid carrier protein
F9Y86_RS06860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F9Y86_RS06870	COG0584	glycerophosphoryl diester phosphodiesterase
F9Y86_RS06875	COG1288	antiporter activity
F9Y86_RS06890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F9Y86_RS06905	COG1999	signal sequence binding
F9Y86_RS06920	COG0527	aspartate kinase activity
F9Y86_RS06920	COG0460	homoserine dehydrogenase
F9Y86_RS06930	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F9Y86_RS06945	COG1309	transcriptional regulator
F9Y86_RS06950	COG0626	cystathionine gamma-synthase activity
F9Y86_RS06995	COG1408	metallophosphoesterase
F9Y86_RS07000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9Y86_RS07000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9Y86_RS07005	COG2378	regulation of single-species biofilm formation
F9Y86_RS07025	COG1040	competence protein
F9Y86_RS07045	COG0423	glycine-tRNA ligase activity
F9Y86_RS07060	COG1629	transport
F9Y86_RS07065	COG0196	riboflavin kinase activity
F9Y86_RS07075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F9Y86_RS07095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9Y86_RS07100	COG2239	Acts as a magnesium transporter
F9Y86_RS07130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F9Y86_RS07135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F9Y86_RS07150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F9Y86_RS07155	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F9Y86_RS07160	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F9Y86_RS07165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F9Y86_RS07170	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F9Y86_RS07175	COG0356	it plays a direct role in the translocation of protons across the membrane
F9Y86_RS07215	COG4932	domain protein
F9Y86_RS07215	COG1388	LysM domain
F9Y86_RS07220	COG0708	Exodeoxyribonuclease III
F9Y86_RS07230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9Y86_RS07235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9Y86_RS07245	COG1774	PSP1 C-terminal conserved region
F9Y86_RS07250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9Y86_RS07270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9Y86_RS07290	COG0189	ligase activity
F9Y86_RS07300	COG0513	Belongs to the DEAD box helicase family
F9Y86_RS07310	COG0006	proline dipeptidase activity
F9Y86_RS07395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9Y86_RS07410	COG1053	succinate dehydrogenase
F9Y86_RS07415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9Y86_RS07430	COG4221	oxidoreductase activity
F9Y86_RS07455	COG3842	ATPase activity
F9Y86_RS07475	COG0189	ligase activity
F9Y86_RS07485	COG3590	peptidase
F9Y86_RS07490	COG1505	serine-type exopeptidase activity
F9Y86_RS07505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9Y86_RS07505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F9Y86_RS07510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F9Y86_RS07520	COG2095	MarC family integral membrane protein
F9Y86_RS07530	COG2356	endonuclease I
F9Y86_RS07535	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS07555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F9Y86_RS07590	COG1595	DNA-templated transcription, initiation
F9Y86_RS07600	COG1446	asparaginase
F9Y86_RS07605	COG1012	belongs to the aldehyde dehydrogenase family
F9Y86_RS07620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F9Y86_RS07625	COG0756	dUTP diphosphatase activity
F9Y86_RS07630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F9Y86_RS07635	COG1187	pseudouridine synthase activity
F9Y86_RS07645	COG2153	protein acetylation
F9Y86_RS07650	COG0698	ribose 5-phosphate isomerase
F9Y86_RS07655	COG1597	lipid kinase activity
F9Y86_RS07660	COG0557	exoribonuclease II activity
F9Y86_RS07675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F9Y86_RS07680	COG0393	Putative heavy-metal-binding
F9Y86_RS07695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9Y86_RS07700	COG0445	tRNA wobble uridine modification
F9Y86_RS07705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F9Y86_RS07725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9Y86_RS07765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9Y86_RS07770	COG2827	Endonuclease containing a URI domain
F9Y86_RS07785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F9Y86_RS07785	COG0758	DNA mediated transformation
F9Y86_RS07800	COG0628	permease
F9Y86_RS07820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9Y86_RS07845	COG4733	cellulase activity
F9Y86_RS07845	COG5297	Belongs to the glycosyl hydrolase family 6
F9Y86_RS07850	COG0488	(ABC) transporter
F9Y86_RS07865	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS07870	COG5002	protein histidine kinase activity
F9Y86_RS07875	COG0151	Belongs to the GarS family
F9Y86_RS07885	COG0793	Belongs to the peptidase S41A family
F9Y86_RS07890	COG0594	ribonuclease P activity
F9Y86_RS07905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F9Y86_RS07915	COG4585	Histidine kinase
F9Y86_RS07920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9Y86_RS07925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F9Y86_RS07930	COG0302	gtp cyclohydrolase
F9Y86_RS07950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F9Y86_RS07960	COG3708	Transcriptional regulator
F9Y86_RS07960	COG2207	Transcriptional regulator
F9Y86_RS07975	COG0720	synthase
F9Y86_RS07980	COG0193	aminoacyl-tRNA hydrolase activity
F9Y86_RS07985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F9Y86_RS07990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9Y86_RS08000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F9Y86_RS08005	COG0746	molybdenum cofactor guanylyltransferase activity
F9Y86_RS08005	COG0315	cyclic pyranopterin monophosphate synthase activity
F9Y86_RS08020	COG0303	'Molybdopterin
F9Y86_RS08025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9Y86_RS08030	COG0322	excinuclease ABC activity
F9Y86_RS08035	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9Y86_RS08040	COG1530	ribonuclease E activity
F9Y86_RS08045	COG0776	regulation of translation
F9Y86_RS08065	COG4771	TonB-dependent receptor
F9Y86_RS08070	COG1194	a g-specific adenine glycosylase
F9Y86_RS08075	COG0629	single-stranded DNA binding
F9Y86_RS08105	COG0612	Peptidase, M16
F9Y86_RS08110	COG0612	Peptidase, M16
F9Y86_RS08115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F9Y86_RS08120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F9Y86_RS08125	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS08130	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS08130	COG2972	Histidine kinase
F9Y86_RS08135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9Y86_RS08145	COG0826	peptidase U32
F9Y86_RS08155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F9Y86_RS08160	COG1418	mRNA catabolic process
F9Y86_RS08165	COG1024	Enoyl-CoA hydratase
F9Y86_RS08170	COG5000	phosphorelay sensor kinase activity
F9Y86_RS08180	COG0470	DNA polymerase III
F9Y86_RS08205	COG1114	Component of the transport system for branched-chain amino acids
F9Y86_RS08215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F9Y86_RS08230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9Y86_RS08245	COG0489	protein tyrosine kinase activity
F9Y86_RS08255	COG0492	ferredoxin-NADP+ reductase activity
F9Y86_RS08265	COG0633	Ferredoxin
F9Y86_RS08270	COG0076	glutamate decarboxylase activity
F9Y86_RS08275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
F9Y86_RS08320	COG1024	Enoyl-CoA hydratase
F9Y86_RS08345	COG4206	TonB-dependent receptor
F9Y86_RS08345	COG1629	transport
F9Y86_RS08360	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F9Y86_RS08365	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F9Y86_RS08385	COG0166	Belongs to the GPI family
F9Y86_RS08390	COG1629	transport
F9Y86_RS08390	COG4206	TonB-dependent receptor
F9Y86_RS08430	COG0314	molybdopterin synthase activity
F9Y86_RS08435	COG0126	phosphoglycerate kinase activity
F9Y86_RS08440	COG0667	Aldo Keto reductase
F9Y86_RS08455	COG0180	Tryptophanyl-tRNA synthetase
F9Y86_RS08465	COG1272	protein, Hemolysin III
F9Y86_RS08475	COG2954	triphosphatase activity
F9Y86_RS08480	COG1381	Involved in DNA repair and RecF pathway recombination
F9Y86_RS08490	COG2814	Major facilitator Superfamily
F9Y86_RS08510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9Y86_RS08515	COG0840	transmembrane signaling receptor activity
F9Y86_RS08520	COG0840	transmembrane signaling receptor activity
F9Y86_RS08530	COG0632	four-way junction helicase activity
F9Y86_RS08540	COG0509	glycine decarboxylation via glycine cleavage system
F9Y86_RS08570	COG1215	transferase activity, transferring glycosyl groups
F9Y86_RS08590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9Y86_RS08610	COG4717	serine-type aminopeptidase activity
F9Y86_RS08635	COG4771	TonB-dependent receptor
F9Y86_RS08655	COG0463	Glycosyl transferase, family 2
F9Y86_RS08665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9Y86_RS08680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9Y86_RS08700	COG1858	cytochrome C peroxidase
F9Y86_RS08725	COG0495	leucyl-tRNA aminoacylation
F9Y86_RS08750	COG1946	Acyl-CoA thioesterase
F9Y86_RS08795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
F9Y86_RS08795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9Y86_RS08810	COG1970	mechanosensitive ion channel activity
F9Y86_RS08820	COG1435	thymidine kinase activity
F9Y86_RS08840	COG0779	Required for maturation of 30S ribosomal subunits
F9Y86_RS08845	COG0195	Participates in both transcription termination and antitermination
F9Y86_RS08845	COG2251	uridine kinase activity
F9Y86_RS08850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F9Y86_RS08875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9Y86_RS08880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F9Y86_RS08895	COG1595	DNA-templated transcription, initiation
F9Y86_RS08925	COG4771	TonB-dependent receptor
F9Y86_RS08955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F9Y86_RS08965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F9Y86_RS09010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F9Y86_RS09025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F9Y86_RS09035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F9Y86_RS09080	COG3209	COG3209 Rhs family protein
F9Y86_RS09145	COG0567	Dehydrogenase, E1 component
F9Y86_RS09150	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9Y86_RS09165	COG2819	hydrolase of the alpha beta superfamily
F9Y86_RS09180	COG0719	Fe-S assembly protein
F9Y86_RS09185	COG0396	ATPase activity
F9Y86_RS09190	COG0719	Fe-S assembly protein
F9Y86_RS09200	COG1858	cytochrome C peroxidase
F9Y86_RS09220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9Y86_RS09225	COG1652	LysM domain
F9Y86_RS09235	COG1561	YicC-like family, N-terminal region
F9Y86_RS09240	COG0194	GDP metabolic process
F9Y86_RS09245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F9Y86_RS09250	COG4942	peptidase
F9Y86_RS09260	COG2258	MOSC domain
F9Y86_RS09275	COG0793	Belongs to the peptidase S41A family
F9Y86_RS09290	COG1522	sequence-specific DNA binding
F9Y86_RS09295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9Y86_RS09310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F9Y86_RS09315	COG2885	chlorophyll binding
F9Y86_RS09320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F9Y86_RS09340	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F9Y86_RS09360	COG2391	methyltransferase activity
F9Y86_RS09365	COG1519	Transferase
F9Y86_RS09365	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9Y86_RS09370	COG0439	Biotin carboxylase
F9Y86_RS09375	COG0511	ligase activity, forming carbon-carbon bonds
F9Y86_RS09380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9Y86_RS09385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F9Y86_RS09395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F9Y86_RS09445	COG1309	transcriptional regulator
F9Y86_RS09475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9Y86_RS09490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9Y86_RS09495	COG1968	undecaprenyl-diphosphatase activity
F9Y86_RS09505	COG2177	Part of the ABC transporter FtsEX involved in
F9Y86_RS09510	COG0346	lactoylglutathione lyase activity
F9Y86_RS09535	COG4585	Histidine kinase
F9Y86_RS09545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F9Y86_RS09550	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9Y86_RS09575	COG0481	GTPase activity
F9Y86_RS09585	COG0252	asparaginase activity
F9Y86_RS09590	COG0811	peptide transport
F9Y86_RS09625	COG0017	Asparaginyl-tRNA synthetase
F9Y86_RS09635	COG0233	cytoplasmic translational termination
F9Y86_RS09640	COG0528	UMP kinase activity
F9Y86_RS09645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F9Y86_RS09650	COG0052	Belongs to the universal ribosomal protein uS2 family
F9Y86_RS09655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F9Y86_RS09660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F9Y86_RS09675	COG1477	protein flavinylation
F9Y86_RS09680	COG2226	methyltransferase
F9Y86_RS09695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9Y86_RS09705	COG0501	Belongs to the peptidase M48B family
F9Y86_RS09730	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F9Y86_RS09780	COG0702	epimerase
F9Y86_RS09790	COG0415	Belongs to the DNA photolyase family
F9Y86_RS09795	COG3046	protein related to deoxyribodipyrimidine photolyase
F9Y86_RS09800	COG0415	Belongs to the DNA photolyase family
F9Y86_RS09820	COG0302	gtp cyclohydrolase
F9Y86_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS09840	COG0386	Belongs to the glutathione peroxidase family
F9Y86_RS09855	COG0415	Belongs to the DNA photolyase family
F9Y86_RS09865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F9Y86_RS09970	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS09970	COG2972	Histidine kinase
F9Y86_RS09975	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS10000	COG2363	Small membrane protein
F9Y86_RS10010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F9Y86_RS10015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F9Y86_RS10060	COG1160	GTP binding
F9Y86_RS10070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9Y86_RS10205	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS10210	COG2972	Histidine kinase
F9Y86_RS10210	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS10230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9Y86_RS10235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9Y86_RS10245	COG1473	amidohydrolase
F9Y86_RS10255	COG3457	Alanine racemase
F9Y86_RS10265	COG2423	ornithine cyclodeaminase activity
F9Y86_RS10275	COG0006	proline dipeptidase activity
F9Y86_RS10280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9Y86_RS10285	COG3938	Belongs to the proline racemase family
F9Y86_RS10295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9Y86_RS10300	COG4977	sequence-specific DNA binding
F9Y86_RS10310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F9Y86_RS10330	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9Y86_RS10340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9Y86_RS10350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9Y86_RS10355	COG0596	Alpha beta hydrolase
F9Y86_RS10380	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9Y86_RS10390	COG1950	PFAM Membrane protein of
F9Y86_RS10395	COG0544	peptidyl-prolyl cis-trans isomerase activity
F9Y86_RS10405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F9Y86_RS10415	COG0358	DNA primase activity
F9Y86_RS10420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F9Y86_RS10435	COG1428	Deoxynucleoside kinase
F9Y86_RS10440	COG1185	polyribonucleotide nucleotidyltransferase activity
F9Y86_RS10445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F9Y86_RS10450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F9Y86_RS10455	COG0191	fructose-bisphosphate aldolase activity
F9Y86_RS10465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9Y86_RS10470	COG0641	radical SAM
F9Y86_RS10480	COG1428	Deoxynucleoside kinase
F9Y86_RS10490	COG0321	lipoyl(octanoyl) transferase activity
F9Y86_RS10500	COG1490	D-aminoacyl-tRNA deacylase activity
F9Y86_RS10505	COG1162	GTPase activity
F9Y86_RS10510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
F9Y86_RS10520	COG0436	Aminotransferase
F9Y86_RS10545	COG3118	belongs to the thioredoxin family
F9Y86_RS10550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F9Y86_RS10560	COG0616	signal peptide processing
F9Y86_RS10570	COG0519	Catalyzes the synthesis of GMP from XMP
F9Y86_RS10585	COG4221	oxidoreductase activity
F9Y86_RS10600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F9Y86_RS10615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9Y86_RS10615	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F9Y86_RS10620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F9Y86_RS10625	COG1607	acyl-coa hydrolase
F9Y86_RS10630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F9Y86_RS10640	COG1252	NADH dehydrogenase
F9Y86_RS10655	COG2363	Small membrane protein
F9Y86_RS10660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F9Y86_RS10665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F9Y86_RS10670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F9Y86_RS10675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9Y86_RS10705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F9Y86_RS10710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F9Y86_RS10715	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F9Y86_RS10735	COG0459	protein refolding
F9Y86_RS10740	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F9Y86_RS10765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9Y86_RS10780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F9Y86_RS10810	COG0488	(ABC) transporter
F9Y86_RS10830	COG0791	NLP P60 protein
F9Y86_RS10830	COG3103	Sh3 type 3 domain protein
F9Y86_RS10830	COG1388	LysM domain
F9Y86_RS10845	COG3275	phosphorelay sensor kinase activity
F9Y86_RS10850	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS10855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9Y86_RS10875	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F9Y86_RS10875	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F9Y86_RS10885	COG0542	response to heat
F9Y86_RS10900	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F9Y86_RS10925	COG1253	flavin adenine dinucleotide binding
F9Y86_RS10940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9Y86_RS10975	COG0339	signal peptide processing
F9Y86_RS10980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F9Y86_RS10985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9Y86_RS10995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9Y86_RS11010	COG3852	Histidine kinase
F9Y86_RS11035	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F9Y86_RS11040	COG2031	fatty acid transporter
F9Y86_RS11045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F9Y86_RS11070	COG1794	racemase activity, acting on amino acids and derivatives
F9Y86_RS11115	COG1032	radical SAM domain protein
F9Y86_RS11125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F9Y86_RS11145	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F9Y86_RS11165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9Y86_RS11175	COG1595	DNA-templated transcription, initiation
F9Y86_RS11185	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F9Y86_RS11210	COG2884	Cell division ATP-binding protein ftsE
F9Y86_RS11215	COG0039	L-malate dehydrogenase activity
F9Y86_RS11230	COG0187	DNA topoisomerase II activity
F9Y86_RS11240	COG0367	asparagine synthase
F9Y86_RS11250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F9Y86_RS11255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9Y86_RS11255	COG0512	Glutamine amidotransferase of anthranilate synthase
F9Y86_RS11260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9Y86_RS11270	COG0134	indole-3-glycerol-phosphate synthase activity
F9Y86_RS11275	COG0135	phosphoribosylanthranilate isomerase activity
F9Y86_RS11280	COG0133	tryptophan synthase activity
F9Y86_RS11285	COG0159	tryptophan synthase activity
F9Y86_RS11290	COG0793	Belongs to the peptidase S41A family
F9Y86_RS11290	COG4946	Tricorn protease homolog
F9Y86_RS11300	COG0514	ATP-dependent DNA helicase (RecQ)
F9Y86_RS11325	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9Y86_RS11325	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F9Y86_RS11325	COG1703	isobutyryl-CoA mutase activity
F9Y86_RS11335	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F9Y86_RS11355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F9Y86_RS11360	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS11365	COG1629	transport
F9Y86_RS11375	COG1629	transport
F9Y86_RS11385	COG0284	orotidine-5'-phosphate decarboxylase activity
F9Y86_RS11390	COG0601	transmembrane transport
F9Y86_RS11400	COG0149	triose-phosphate isomerase activity
F9Y86_RS11405	COG2264	protein methyltransferase activity
F9Y86_RS11410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F9Y86_RS11450	COG0010	Belongs to the arginase family
F9Y86_RS11455	COG1166	arginine decarboxylase activity
F9Y86_RS11475	COG0598	Magnesium transport protein CorA
F9Y86_RS11485	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9Y86_RS11495	COG2217	Heavy metal translocating P-type atpase
F9Y86_RS11505	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
F9Y86_RS11510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9Y86_RS11545	COG0174	glutamine synthetase
F9Y86_RS11585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F9Y86_RS11595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F9Y86_RS11600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9Y86_RS11605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9Y86_RS11635	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9Y86_RS11645	COG0778	Nitroreductase
F9Y86_RS11650	COG1733	regulation of RNA biosynthetic process
F9Y86_RS11655	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9Y86_RS11680	COG3591	Belongs to the peptidase S1B family
F9Y86_RS11755	COG2003	Belongs to the UPF0758 family
F9Y86_RS11805	COG3530	Putative quorum-sensing-regulated virulence factor
F9Y86_RS11815	COG4452	Inner membrane protein CreD
F9Y86_RS11845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F9Y86_RS11855	COG1404	Belongs to the peptidase S8 family
F9Y86_RS11880	COG2373	Large extracellular alpha-helical protein
F9Y86_RS11885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9Y86_RS11915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9Y86_RS11925	COG2003	Belongs to the UPF0758 family
F9Y86_RS11955	COG2855	membrane
F9Y86_RS11960	COG0583	DNA-binding transcription factor activity
F9Y86_RS11965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9Y86_RS11975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9Y86_RS11985	COG1629	transport
F9Y86_RS11985	COG4206	TonB-dependent receptor
F9Y86_RS11995	COG4206	TonB-dependent receptor
F9Y86_RS11995	COG1629	transport
F9Y86_RS12000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F9Y86_RS12005	COG0049	tRNA binding
F9Y86_RS12010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F9Y86_RS12015	COG0051	transcription antitermination factor activity, RNA binding
F9Y86_RS12020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F9Y86_RS12025	COG0088	Forms part of the polypeptide exit tunnel
F9Y86_RS12030	COG0089	rRNA binding
F9Y86_RS12035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F9Y86_RS12040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F9Y86_RS12045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F9Y86_RS12050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F9Y86_RS12055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F9Y86_RS12060	COG0255	Belongs to the universal ribosomal protein uL29 family
F9Y86_RS12065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F9Y86_RS12070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F9Y86_RS12075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F9Y86_RS12080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F9Y86_RS12085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F9Y86_RS12090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F9Y86_RS12095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F9Y86_RS12100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F9Y86_RS12105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F9Y86_RS12110	COG1841	ribosomal large subunit assembly
F9Y86_RS12115	COG0200	Binds to the 23S rRNA
F9Y86_RS12125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F9Y86_RS12130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F9Y86_RS12135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9Y86_RS12140	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F9Y86_RS12145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F9Y86_RS12150	COG0202	RNA polymerase activity
F9Y86_RS12155	COG0203	ribosomal protein L17
F9Y86_RS12160	COG0505	Belongs to the CarA family
F9Y86_RS12165	COG0148	phosphopyruvate hydratase activity
F9Y86_RS12190	COG0010	Belongs to the arginase family
F9Y86_RS12195	COG2104	thiamine diphosphate biosynthetic process
F9Y86_RS12215	COG0352	thiamine-phosphate diphosphorylase activity
F9Y86_RS12220	COG2022	thiamine diphosphate biosynthetic process
F9Y86_RS12225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F9Y86_RS12250	COG1595	DNA-templated transcription, initiation
F9Y86_RS12265	COG0215	cysteine-tRNA ligase activity
F9Y86_RS12270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F9Y86_RS12275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F9Y86_RS12285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F9Y86_RS12315	COG2217	Heavy metal translocating P-type atpase
F9Y86_RS12320	COG2207	Transcriptional regulator
F9Y86_RS12325	COG0542	response to heat
F9Y86_RS12340	COG0791	NLP P60 protein
F9Y86_RS12345	COG0183	Belongs to the thiolase family
F9Y86_RS12380	COG0697	spore germination
F9Y86_RS12385	COG1917	Cupin 2, conserved barrel domain protein
F9Y86_RS12385	COG4977	sequence-specific DNA binding
F9Y86_RS12390	COG3878	Protein conserved in bacteria
F9Y86_RS12405	COG0488	(ABC) transporter
F9Y86_RS12410	COG0653	protein targeting
F9Y86_RS12420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F9Y86_RS12420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F9Y86_RS12430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9Y86_RS12450	COG3844	kynureninase activity
F9Y86_RS12460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9Y86_RS12465	COG1396	sequence-specific DNA binding
F9Y86_RS12475	COG1842	Phage shock protein A
F9Y86_RS12490	COG2255	four-way junction helicase activity
F9Y86_RS12515	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS12520	COG0662	Cupin 2, conserved barrel domain protein
F9Y86_RS12545	COG2274	protein secretion by the type I secretion system
F9Y86_RS12555	COG3104	oligopeptide transport
F9Y86_RS12570	COG4589	Belongs to the CDS family
F9Y86_RS12580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9Y86_RS12585	COG0799	negative regulation of ribosome biogenesis
F9Y86_RS12600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F9Y86_RS12605	COG0494	nUDIX hydrolase
F9Y86_RS12610	COG0443	Heat shock 70 kDa protein
F9Y86_RS12625	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS12625	COG2972	Histidine kinase
F9Y86_RS12630	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS12650	COG1252	NADH dehydrogenase
F9Y86_RS12680	COG4656	Part of a membrane complex involved in electron transport
F9Y86_RS12705	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9Y86_RS12755	COG2814	Major facilitator Superfamily
F9Y86_RS12760	COG0656	L-ascorbic acid biosynthetic process
F9Y86_RS12770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9Y86_RS12770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9Y86_RS12785	COG1674	ftsk spoiiie
F9Y86_RS12800	COG0534	Mate efflux family protein
F9Y86_RS12830	COG0456	acetyltransferase
F9Y86_RS12850	COG0277	FAD linked oxidase domain protein
F9Y86_RS12850	COG0247	lactate metabolic process
F9Y86_RS12860	COG5383	Protein conserved in bacteria
F9Y86_RS12870	COG0556	nucleotide-excision repair
F9Y86_RS12895	COG1131	(ABC) transporter
F9Y86_RS12915	COG0237	dephospho-CoA kinase activity
F9Y86_RS12925	COG1862	Preprotein translocase
F9Y86_RS12935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9Y86_RS12945	COG1132	(ABC) transporter
F9Y86_RS12955	COG1169	isochorismate synthase
F9Y86_RS12975	COG0009	L-threonylcarbamoyladenylate synthase
F9Y86_RS13005	COG0531	amino acid
F9Y86_RS13015	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F9Y86_RS13020	COG1959	2 iron, 2 sulfur cluster binding
F9Y86_RS13040	COG0534	Mate efflux family protein
F9Y86_RS13045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F9Y86_RS13105	COG2201	protein-glutamate methylesterase activity
F9Y86_RS13110	COG4251	negative regulation of phosphorylation
F9Y86_RS13120	COG1917	Cupin 2, conserved barrel domain protein
F9Y86_RS13120	COG4977	sequence-specific DNA binding
F9Y86_RS13150	COG1678	Uncharacterized ACR, COG1678
F9Y86_RS13155	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS13160	COG3275	phosphorelay sensor kinase activity
F9Y86_RS13210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F9Y86_RS13225	COG1595	DNA-templated transcription, initiation
F9Y86_RS13230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9Y86_RS13235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9Y86_RS13255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9Y86_RS13270	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
F9Y86_RS13275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
F9Y86_RS13300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F9Y86_RS13315	COG0653	protein targeting
F9Y86_RS13325	COG2096	Adenosyltransferase
F9Y86_RS13330	COG0824	Thioesterase
F9Y86_RS13335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F9Y86_RS13340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9Y86_RS13345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F9Y86_RS13355	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9Y86_RS13360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9Y86_RS13365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F9Y86_RS13370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9Y86_RS13390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F9Y86_RS13420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9Y86_RS13425	COG1528	Iron-storage protein
F9Y86_RS13450	COG0497	DNA recombination
F9Y86_RS13460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F9Y86_RS13470	COG1216	Glycosyl transferase, family 2
F9Y86_RS13475	COG0612	Peptidase, M16
F9Y86_RS13480	COG5183	chlorophyll binding
F9Y86_RS13480	COG2133	pyrroloquinoline quinone binding
F9Y86_RS13515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9Y86_RS13525	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9Y86_RS13535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F9Y86_RS13545	COG1482	cell wall glycoprotein biosynthetic process
F9Y86_RS13555	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F9Y86_RS13560	COG1011	Hydrolase
F9Y86_RS13590	COG1595	DNA-templated transcription, initiation
F9Y86_RS13600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F9Y86_RS13600	COG0321	lipoyl(octanoyl) transferase activity
F9Y86_RS13605	COG3022	response to hydroperoxide
F9Y86_RS13610	COG2949	membrane
F9Y86_RS13615	COG1760	l-serine dehydratase
F9Y86_RS13630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9Y86_RS13635	COG0205	6-phosphofructokinase activity
F9Y86_RS13640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9Y86_RS13645	COG1803	Methylglyoxal synthase
F9Y86_RS13650	COG0251	oxidation-reduction process
F9Y86_RS13655	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F9Y86_RS13660	COG0860	N-Acetylmuramoyl-L-alanine amidase
F9Y86_RS13670	COG2181	nitrate reductase activity
F9Y86_RS13670	COG0247	lactate metabolic process
F9Y86_RS13675	COG2181	nitrate reductase activity
F9Y86_RS13675	COG0247	lactate metabolic process
F9Y86_RS13685	COG1575	Belongs to the MenA family. Type 1 subfamily
F9Y86_RS13695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F9Y86_RS13705	COG4948	Mandelate Racemase Muconate Lactonizing
F9Y86_RS13710	COG1266	CAAX protease self-immunity
F9Y86_RS13720	COG2304	oxidoreductase activity
F9Y86_RS13725	COG0217	transcriptional regulatory protein
F9Y86_RS13735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9Y86_RS13745	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9Y86_RS13795	COG1846	Transcriptional regulator
F9Y86_RS13805	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9Y86_RS13805	COG1902	pentaerythritol trinitrate reductase activity
F9Y86_RS13815	COG0488	(ABC) transporter
F9Y86_RS13830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9Y86_RS13835	COG0018	arginyl-trna synthetase
F9Y86_RS13885	COG0482	sulfurtransferase activity
F9Y86_RS13905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9Y86_RS13910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F9Y86_RS13915	COG0066	3-isopropylmalate dehydratase activity
F9Y86_RS13940	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS13955	COG1942	4-Oxalocrotonate Tautomerase
F9Y86_RS14010	COG0010	Belongs to the arginase family
F9Y86_RS14015	COG1228	amidohydrolase
F9Y86_RS14035	COG0668	transmembrane transport
F9Y86_RS14050	COG1301	dicarboxylic acid transport
F9Y86_RS14055	COG2897	thiosulfate sulfurtransferase activity
F9Y86_RS14075	COG0210	DNA helicase
F9Y86_RS14085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F9Y86_RS14095	COG0583	DNA-binding transcription factor activity
F9Y86_RS14100	COG4221	oxidoreductase activity
F9Y86_RS14115	COG0776	regulation of translation
F9Y86_RS14120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F9Y86_RS14125	COG0514	ATP-dependent DNA helicase (RecQ)
F9Y86_RS14145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9Y86_RS14150	COG0714	Associated with various cellular activities
F9Y86_RS14160	COG1733	regulation of RNA biosynthetic process
F9Y86_RS14165	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F9Y86_RS14170	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9Y86_RS14180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F9Y86_RS14190	COG0813	purine-nucleoside phosphorylase activity
F9Y86_RS14220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F9Y86_RS14235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9Y86_RS14240	COG0706	membrane insertase activity
F9Y86_RS14245	COG0504	CTP synthase activity
F9Y86_RS14250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F9Y86_RS14260	COG0716	FMN binding
F9Y86_RS14265	COG1607	acyl-coa hydrolase
F9Y86_RS14285	COG3712	iron ion homeostasis
F9Y86_RS14290	COG1595	DNA-templated transcription, initiation
F9Y86_RS14300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F9Y86_RS14305	COG1181	Belongs to the D-alanine--D-alanine ligase family
F9Y86_RS14315	COG0564	pseudouridine synthase activity
F9Y86_RS14320	COG0531	amino acid
F9Y86_RS14350	COG0165	Argininosuccinate lyase
F9Y86_RS14360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F9Y86_RS14370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9Y86_RS14375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F9Y86_RS14380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F9Y86_RS14385	COG0137	argininosuccinate synthase activity
F9Y86_RS14400	COG0129	dihydroxy-acid dehydratase activity
F9Y86_RS14405	COG0028	Belongs to the TPP enzyme family
F9Y86_RS14415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F9Y86_RS14420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9Y86_RS14425	COG3012	SEC-C Motif Domain Protein
F9Y86_RS14440	COG0784	Response regulator, receiver
F9Y86_RS14450	COG4251	negative regulation of phosphorylation
F9Y86_RS14460	COG3279	Response regulator of the LytR AlgR family
F9Y86_RS14505	COG0745	RESPONSE REGULATOR receiver
F9Y86_RS14545	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F9Y86_RS14585	COG2373	Large extracellular alpha-helical protein
F9Y86_RS14590	COG4953	penicillin-binding protein 1C
F9Y86_RS14595	COG3263	regulation of cellular component size
F9Y86_RS14600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9Y86_RS14605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9Y86_RS14625	COG1253	flavin adenine dinucleotide binding
F9Y86_RS14665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F9Y86_RS14670	COG0484	heat shock protein binding
F9Y86_RS14680	COG1049	propionate catabolic process, 2-methylcitrate cycle
F9Y86_RS14710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F9Y86_RS14740	COG0798	PFAM Bile acid sodium symporter
F9Y86_RS14760	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
F9Y86_RS14765	COG1702	phosphate starvation-inducible protein PhoH
F9Y86_RS14775	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F9Y86_RS14785	COG2010	Cytochrome c
F9Y86_RS14785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F9Y86_RS14790	COG0156	8-amino-7-oxononanoate synthase activity
F9Y86_RS14840	COG0671	phosphoesterase, PA-phosphatase related
F9Y86_RS14845	COG2259	Doxx family
F9Y86_RS14850	COG0671	phosphoesterase, PA-phosphatase related
F9Y86_RS14860	COG2207	Transcriptional regulator
F9Y86_RS14860	COG0662	Cupin 2, conserved barrel domain protein
F9Y86_RS14870	COG3547	Transposase (IS116 IS110 IS902 family)
F9Y86_RS14885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9Y86_RS14895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9Y86_RS14975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F9Y86_RS14985	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
F9Y86_RS14995	COG4206	TonB-dependent receptor
F9Y86_RS15005	COG3011	Protein conserved in bacteria
F9Y86_RS15010	COG1136	(ABC) transporter
F9Y86_RS15015	COG1136	(ABC) transporter
F9Y86_RS15015	COG0577	efflux transmembrane transporter activity
F9Y86_RS15020	COG1136	(ABC) transporter
F9Y86_RS15020	COG0577	efflux transmembrane transporter activity
F9Y86_RS15030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F9Y86_RS15035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9Y86_RS15050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9Y86_RS15075	COG1028	Short-chain dehydrogenase reductase Sdr
F9Y86_RS15080	COG3956	TIGRFAM MazG family protein
F9Y86_RS15090	COG0242	peptide deformylase activity
F9Y86_RS15095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9Y86_RS15110	COG0009	L-threonylcarbamoyladenylate synthase
F9Y86_RS15115	COG3119	arylsulfatase activity
F9Y86_RS15120	COG0517	IMP dehydrogenase activity
F9Y86_RS15120	COG0617	tRNA 3'-terminal CCA addition
F9Y86_RS15120	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F9Y86_RS15125	COG1132	(ABC) transporter
F9Y86_RS15130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9Y86_RS15135	COG0463	Glycosyl transferase, family 2
F9Y86_RS15150	COG4974	Belongs to the 'phage' integrase family
F9Y86_RS15165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F9Y86_RS15180	COG1183	phosphatidylcholine synthase activity
F9Y86_RS15195	COG0805	protein transport
F9Y86_RS15200	COG0517	IMP dehydrogenase activity
F9Y86_RS15200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9Y86_RS15205	COG0514	ATP-dependent DNA helicase (RecQ)
F9Y86_RS15225	COG0686	Belongs to the AlaDH PNT family
F9Y86_RS15230	COG0802	atpase or kinase
F9Y86_RS15235	COG2204	response regulator
F9Y86_RS15240	COG1078	dGTPase activity
F9Y86_RS15245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9Y86_RS15255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9Y86_RS15260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase