locus-tag	class	description
B2J85_RS00020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B2J85_RS00030	COG1461	Dihydroxyacetone kinase
B2J85_RS00035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B2J85_RS00040	COG0416	fatty acid biosynthetic process
B2J85_RS00045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2J85_RS00050	COG0571	ribonuclease III activity
B2J85_RS00055	COG1196	nuclear chromosome segregation
B2J85_RS00060	COG0561	phosphatase activity
B2J85_RS00065	COG0552	protein localization to endoplasmic reticulum
B2J85_RS00085	COG2918	glutathione biosynthetic process
B2J85_RS00085	COG1181	Belongs to the D-alanine--D-alanine ligase family
B2J85_RS00100	COG0519	Catalyzes the synthesis of GMP from XMP
B2J85_RS00110	COG4493	Belongs to the UPF0637 family
B2J85_RS00115	COG1268	BioY protein
B2J85_RS00125	COG3279	Response regulator of the LytR AlgR family
B2J85_RS00140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B2J85_RS00150	COG0561	phosphatase activity
B2J85_RS00185	COG1692	metallophosphoesterase
B2J85_RS00190	COG4550	Control of competence regulator ComK, YlbF/YmcA
B2J85_RS00195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B2J85_RS00230	COG0632	four-way junction helicase activity
B2J85_RS00235	COG2255	four-way junction helicase activity
B2J85_RS00240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B2J85_RS00250	COG1114	Component of the transport system for branched-chain amino acids
B2J85_RS00255	COG1126	abc transporter atp-binding protein
B2J85_RS00260	COG0765	amino acid transport
B2J85_RS00275	COG0110	maltose O-acetyltransferase activity
B2J85_RS00280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B2J85_RS00285	COG2011	ABC-type metal ion transport system permease component
B2J85_RS00290	COG1464	Belongs to the NlpA lipoprotein family
B2J85_RS00295	COG0242	peptide deformylase activity
B2J85_RS00305	COG4149	molybdate abc transporter
B2J85_RS00315	COG0521	Mo-molybdopterin cofactor biosynthetic process
B2J85_RS00325	COG0725	ABC transporter, periplasmic molybdate-binding protein
B2J85_RS00340	COG1132	(ABC) transporter
B2J85_RS00345	COG1131	(ABC) transporter
B2J85_RS00350	COG4473	ABC transporter
B2J85_RS00360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B2J85_RS00365	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS00375	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS00380	COG0561	phosphatase activity
B2J85_RS00390	COG0589	response to stress
B2J85_RS00420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B2J85_RS00425	COG2094	Belongs to the DNA glycosylase MPG family
B2J85_RS00430	COG2264	protein methyltransferase activity
B2J85_RS00435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B2J85_RS00440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B2J85_RS00445	COG1490	D-aminoacyl-tRNA deacylase activity
B2J85_RS00470	COG0531	amino acid
B2J85_RS00475	COG3853	Toxic anion resistance protein (TelA)
B2J85_RS00495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2J85_RS00500	COG3590	peptidase
B2J85_RS00515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B2J85_RS00520	COG1104	cysteine desulfurase activity
B2J85_RS00530	COG0482	sulfurtransferase activity
B2J85_RS00565	COG3842	ATPase activity
B2J85_RS00570	COG2508	Transcriptional regulator
B2J85_RS00575	COG0765	amino acid transport
B2J85_RS00580	COG1126	abc transporter atp-binding protein
B2J85_RS00585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2J85_RS00590	COG1674	ftsk spoiiie
B2J85_RS00595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B2J85_RS00600	COG4166	transmembrane transport
B2J85_RS00605	COG4166	transmembrane transport
B2J85_RS00615	COG0601	transmembrane transport
B2J85_RS00620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2J85_RS00625	COG0444	Belongs to the ABC transporter superfamily
B2J85_RS00630	COG4608	Belongs to the ABC transporter superfamily
B2J85_RS00640	COG2239	Acts as a magnesium transporter
B2J85_RS00655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2J85_RS00655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2J85_RS00660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B2J85_RS00675	COG0488	(ABC) transporter
B2J85_RS00680	COG2706	6-phosphogluconolactonase activity
B2J85_RS00690	COG0628	permease
B2J85_RS00700	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B2J85_RS00705	COG1185	polyribonucleotide nucleotidyltransferase activity
B2J85_RS00725	COG0719	Fe-S assembly protein
B2J85_RS00730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B2J85_RS00745	COG1132	(ABC) transporter
B2J85_RS00750	COG1132	(ABC) transporter
B2J85_RS00760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2J85_RS00780	COG0114	fumarate hydratase activity
B2J85_RS00795	COG2610	gluconate transmembrane transporter activity
B2J85_RS00800	COG1070	Carbohydrate kinase
B2J85_RS00805	COG1053	succinate dehydrogenase
B2J85_RS00805	COG3976	FMN-binding domain protein
B2J85_RS00805	COG0431	NADPH-dependent FMN reductase
B2J85_RS00815	COG1428	Deoxynucleoside kinase
B2J85_RS00820	COG3104	oligopeptide transport
B2J85_RS00830	COG1132	(ABC) transporter
B2J85_RS00835	COG1174	glycine betaine transport
B2J85_RS00850	COG2226	methyltransferase
B2J85_RS00870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2J85_RS00875	COG3527	Alpha-acetolactate decarboxylase
B2J85_RS00880	COG0693	protein deglycase activity
B2J85_RS00885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B2J85_RS00890	COG0626	cystathionine gamma-synthase activity
B2J85_RS00895	COG1045	serine acetyltransferase
B2J85_RS00925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS00925	COG3711	transcriptional antiterminator
B2J85_RS00935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS00935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS00935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS00940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS00950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS00965	COG0719	Fe-S assembly protein
B2J85_RS00970	COG3608	succinylglutamate desuccinylase aspartoacylase
B2J85_RS00970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B2J85_RS00995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B2J85_RS01000	COG3608	succinylglutamate desuccinylase aspartoacylase
B2J85_RS01000	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B2J85_RS01010	COG0402	S-adenosylhomocysteine deaminase activity
B2J85_RS01020	COG0716	FMN binding
B2J85_RS01025	COG0543	2 iron, 2 sulfur cluster binding
B2J85_RS01030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B2J85_RS01030	COG0493	'glutamate synthase
B2J85_RS01040	COG0028	Belongs to the TPP enzyme family
B2J85_RS01045	COG2171	N-acyltransferase activity
B2J85_RS01050	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B2J85_RS01055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2J85_RS01060	COG1473	amidohydrolase
B2J85_RS01065	COG0019	diaminopimelate decarboxylase activity
B2J85_RS01070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B2J85_RS01075	COG2738	Putative neutral zinc metallopeptidase
B2J85_RS01085	COG0590	tRNA wobble adenosine to inosine editing
B2J85_RS01100	COG0737	Belongs to the 5'-nucleotidase family
B2J85_RS01105	COG4470	Protein conserved in bacteria
B2J85_RS01110	COG0647	UMP catabolic process
B2J85_RS01125	COG0095	Lipoate-protein ligase
B2J85_RS01135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B2J85_RS01140	COG4656	Part of a membrane complex involved in electron transport
B2J85_RS01145	COG4658	electron transport chain
B2J85_RS01155	COG1131	(ABC) transporter
B2J85_RS01170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B2J85_RS01180	COG2827	Endonuclease containing a URI domain
B2J85_RS01185	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B2J85_RS01190	COG0204	Acyl-transferase
B2J85_RS01195	COG0420	3'-5' exonuclease activity
B2J85_RS01200	COG0419	ATPase involved in DNA repair
B2J85_RS01205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2J85_RS01215	COG1393	Belongs to the ArsC family
B2J85_RS01220	COG4862	establishment of competence for transformation
B2J85_RS01230	COG1164	Oligoendopeptidase f
B2J85_RS01235	COG4116	CYTH
B2J85_RS01240	COG2357	RelA SpoT domain protein
B2J85_RS01245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B2J85_RS01250	COG0564	pseudouridine synthase activity
B2J85_RS01255	COG2239	Acts as a magnesium transporter
B2J85_RS01260	COG3142	Participates in the control of copper homeostasis
B2J85_RS01265	COG0500	methyltransferase
B2J85_RS01270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B2J85_RS01280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B2J85_RS01285	COG4708	membrane
B2J85_RS01295	COG1597	lipid kinase activity
B2J85_RS01305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B2J85_RS01310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2J85_RS01315	COG0250	Participates in transcription elongation, termination and antitermination
B2J85_RS01330	COG0081	regulation of translation
B2J85_RS01335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B2J85_RS01340	COG0222	ribosome binding
B2J85_RS01345	COG2910	NAD(P)H-binding
B2J85_RS01350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS01355	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS01360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B2J85_RS01365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B2J85_RS01370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B2J85_RS01375	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B2J85_RS01380	COG3870	Protein conserved in bacteria
B2J85_RS01385	COG0470	DNA polymerase III
B2J85_RS01390	COG1774	PSP1 C-terminal conserved region
B2J85_RS01395	COG4467	Involved in initiation control of chromosome replication
B2J85_RS01410	COG0602	queuosine metabolic process
B2J85_RS01420	COG0095	Lipoate-protein ligase
B2J85_RS01425	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS01430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2J85_RS01435	COG4122	O-methyltransferase activity
B2J85_RS01445	COG3385	transposase activity
B2J85_RS01450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B2J85_RS01460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B2J85_RS01470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS01470	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS01475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS01475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS01485	COG3715	PTS system
B2J85_RS01490	COG3716	PTS system mannose fructose sorbose family IID component
B2J85_RS01505	COG4864	UPF0365 protein
B2J85_RS01515	COG0006	proline dipeptidase activity
B2J85_RS01520	COG1302	Protein conserved in bacteria
B2J85_RS01525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2J85_RS01530	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B2J85_RS01535	COG1570	exodeoxyribonuclease VII activity
B2J85_RS01540	COG1722	exodeoxyribonuclease VII activity
B2J85_RS01550	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B2J85_RS01555	COG1438	arginine binding
B2J85_RS01560	COG0497	DNA recombination
B2J85_RS01580	COG2001	Belongs to the MraZ family
B2J85_RS01595	COG0768	penicillin binding
B2J85_RS01605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B2J85_RS01630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B2J85_RS01635	COG1799	cell septum assembly
B2J85_RS01640	COG0762	integral membrane protein
B2J85_RS01645	COG2302	S4 RNA-binding domain
B2J85_RS01650	COG3599	regulation of cell shape
B2J85_RS01655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B2J85_RS01660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B2J85_RS01670	COG2309	aminopeptidase activity
B2J85_RS01675	COG1309	transcriptional regulator
B2J85_RS01680	COG0716	FMN binding
B2J85_RS01685	COG0024	Methionine aminopeptidase
B2J85_RS01690	COG1295	ribonuclease BN
B2J85_RS01695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2J85_RS01700	COG3682	Transcriptional regulator
B2J85_RS01705	COG2608	mercury ion transmembrane transporter activity
B2J85_RS01715	COG0436	Aminotransferase
B2J85_RS01720	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B2J85_RS01725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2J85_RS01740	COG0655	NAD(P)H dehydrogenase (quinone) activity
B2J85_RS01745	COG0228	four-way junction DNA binding
B2J85_RS01750	COG1837	Belongs to the UPF0109 family
B2J85_RS01760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B2J85_RS01765	COG0511	ligase activity, forming carbon-carbon bonds
B2J85_RS01790	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B2J85_RS01800	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B2J85_RS01805	COG3052	prosthetic group binding
B2J85_RS01835	COG0336	Belongs to the RNA methyltransferase TrmD family
B2J85_RS01840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B2J85_RS01850	COG3830	Belongs to the UPF0237 family
B2J85_RS01855	COG2848	UPF0210 protein
B2J85_RS01860	COG1956	GAF domain-containing protein
B2J85_RS01870	COG0582	viral genome integration into host DNA
B2J85_RS01925	COG0584	glycerophosphoryl diester phosphodiesterase
B2J85_RS01955	COG0745	RESPONSE REGULATOR receiver
B2J85_RS01960	COG3850	Histidine kinase
B2J85_RS01960	COG5002	protein histidine kinase activity
B2J85_RS01975	COG1368	sulfuric ester hydrolase activity
B2J85_RS01980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B2J85_RS01985	COG0710	3-dehydroquinate dehydratase activity
B2J85_RS01990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B2J85_RS01995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B2J85_RS02000	COG0166	Belongs to the GPI family
B2J85_RS02040	COG0561	phosphatase activity
B2J85_RS02045	COG2252	PERMEase
B2J85_RS02055	COG0587	DNA-directed DNA polymerase activity
B2J85_RS02060	COG0205	6-phosphofructokinase activity
B2J85_RS02070	COG1399	metal-binding, possibly nucleic acid-binding protein
B2J85_RS02075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B2J85_RS02090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B2J85_RS02095	COG0745	RESPONSE REGULATOR receiver
B2J85_RS02100	COG5002	protein histidine kinase activity
B2J85_RS02180	COG2190	(PTS) system
B2J85_RS02195	COG3344	reverse transcriptase
B2J85_RS02200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B2J85_RS02205	COG1349	DNA-binding transcription factor activity
B2J85_RS02210	COG1882	Formate acetyltransferase
B2J85_RS02225	COG1464	Belongs to the NlpA lipoprotein family
B2J85_RS02230	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS02240	COG3425	synthase
B2J85_RS02260	COG0741	lytic transglycosylase activity
B2J85_RS02270	COG0358	DNA primase activity
B2J85_RS02275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B2J85_RS02290	COG2996	Protein conserved in bacteria
B2J85_RS02295	COG0735	belongs to the Fur family
B2J85_RS02300	COG4974	Belongs to the 'phage' integrase family
B2J85_RS02305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B2J85_RS02310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B2J85_RS02315	COG1187	pseudouridine synthase activity
B2J85_RS02320	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B2J85_RS02325	COG1141	Ferredoxin
B2J85_RS02335	COG0514	ATP-dependent DNA helicase (RecQ)
B2J85_RS02355	COG0539	negative regulation of cytoplasmic translation
B2J85_RS02360	COG1160	GTP binding
B2J85_RS02365	COG0776	regulation of translation
B2J85_RS02375	COG0457	Tetratricopeptide repeat
B2J85_RS02380	COG5582	Belongs to the UPF0302 family
B2J85_RS02385	COG1694	Mazg nucleotide pyrophosphohydrolase
B2J85_RS02390	COG0617	tRNA 3'-terminal CCA addition
B2J85_RS02410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B2J85_RS02415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B2J85_RS02430	COG1940	carbohydrate kinase activity
B2J85_RS02435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2J85_RS02445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B2J85_RS02450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B2J85_RS02455	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B2J85_RS02460	COG1609	Transcriptional regulator
B2J85_RS02465	COG0110	maltose O-acetyltransferase activity
B2J85_RS02470	COG1609	Transcriptional regulator
B2J85_RS02505	COG1214	PFAM Peptidase M22, glycoprotease
B2J85_RS02520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B2J85_RS02525	COG0052	Belongs to the universal ribosomal protein uS2 family
B2J85_RS02530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B2J85_RS02535	COG0528	UMP kinase activity
B2J85_RS02540	COG0233	cytoplasmic translational termination
B2J85_RS02545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B2J85_RS02550	COG4589	Belongs to the CDS family
B2J85_RS02555	COG0750	zinc metalloprotease
B2J85_RS02560	COG0442	prolyl-tRNA aminoacylation
B2J85_RS02570	COG2137	regulation of response to DNA damage stimulus
B2J85_RS02580	COG3557	Belongs to the UPF0374 family
B2J85_RS02590	COG1253	flavin adenine dinucleotide binding
B2J85_RS02595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B2J85_RS02605	COG0542	response to heat
B2J85_RS02615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS02620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2J85_RS02635	COG0438	transferase activity, transferring glycosyl groups
B2J85_RS02640	COG2084	Dehydrogenase
B2J85_RS02645	COG4703	Protein of unknown function (DUF1797)
B2J85_RS02650	COG1428	Deoxynucleoside kinase
B2J85_RS02660	COG1846	Transcriptional regulator
B2J85_RS02665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B2J85_RS02670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2J85_RS02675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B2J85_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
B2J85_RS02690	COG0511	ligase activity, forming carbon-carbon bonds
B2J85_RS02695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B2J85_RS02700	COG0439	Biotin carboxylase
B2J85_RS02705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B2J85_RS02710	COG0825	malonyl-CoA metabolic process
B2J85_RS02715	COG1607	acyl-coa hydrolase
B2J85_RS02735	COG4152	abc transporter atp-binding protein
B2J85_RS02740	COG1668	transmembrane transport
B2J85_RS02745	COG2084	Dehydrogenase
B2J85_RS02750	COG0583	DNA-binding transcription factor activity
B2J85_RS02760	COG3344	reverse transcriptase
B2J85_RS02790	COG1725	Transcriptional regulator
B2J85_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2J85_RS02815	COG3394	polysaccharide catabolic process
B2J85_RS02820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B2J85_RS02845	COG2188	Transcriptional regulator
B2J85_RS02850	COG0366	Alpha amylase catalytic
B2J85_RS02870	COG2182	Extracellular solute-binding protein
B2J85_RS02875	COG1175	transmembrane transport
B2J85_RS02885	COG1175	transmembrane transport
B2J85_RS02890	COG3833	ABC-type maltose transport systems, permease component
B2J85_RS02900	COG1349	DNA-binding transcription factor activity
B2J85_RS02905	COG0191	fructose-bisphosphate aldolase activity
B2J85_RS02910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS02910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS02910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS02915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS02930	COG1070	Carbohydrate kinase
B2J85_RS02935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2J85_RS02940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS02970	COG1373	ATPase (AAA superfamily
B2J85_RS02975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2J85_RS02980	COG0765	amino acid transport
B2J85_RS03035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B2J85_RS03045	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS03050	COG3775	system Galactitol-specific IIC component
B2J85_RS03080	COG4684	Psort location CytoplasmicMembrane, score
B2J85_RS03085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B2J85_RS03095	COG0604	alcohol dehydrogenase
B2J85_RS03100	COG0346	lactoylglutathione lyase activity
B2J85_RS03110	COG0686	Belongs to the AlaDH PNT family
B2J85_RS03115	COG0488	(ABC) transporter
B2J85_RS03120	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B2J85_RS03125	COG4472	Bacterial protein of unknown function (DUF965)
B2J85_RS03130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B2J85_RS03135	COG3906	Belongs to the UPF0473 family
B2J85_RS03145	COG1464	Belongs to the NlpA lipoprotein family
B2J85_RS03150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2J85_RS03155	COG4175	Glycine betaine
B2J85_RS03155	COG3448	diguanylate cyclase activity
B2J85_RS03180	COG2059	Chromate
B2J85_RS03190	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B2J85_RS03205	COG1193	negative regulation of DNA recombination
B2J85_RS03210	COG3118	belongs to the thioredoxin family
B2J85_RS03220	COG0346	lactoylglutathione lyase activity
B2J85_RS03230	COG2816	NAD+ diphosphatase activity
B2J85_RS03235	COG1078	dGTPase activity
B2J85_RS03240	COG0095	Lipoate-protein ligase
B2J85_RS03255	COG0584	glycerophosphoryl diester phosphodiesterase
B2J85_RS03270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B2J85_RS03275	COG2390	Transcriptional regulator
B2J85_RS03285	COG0126	phosphoglycerate kinase activity
B2J85_RS03290	COG0149	triose-phosphate isomerase activity
B2J85_RS03295	COG0148	phosphopyruvate hydratase activity
B2J85_RS03300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B2J85_RS03310	COG0557	exoribonuclease II activity
B2J85_RS03315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B2J85_RS03320	COG0356	it plays a direct role in the translocation of protons across the membrane
B2J85_RS03325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2J85_RS03330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B2J85_RS03335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2J85_RS03340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B2J85_RS03345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B2J85_RS03350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B2J85_RS03355	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B2J85_RS03365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2J85_RS03375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B2J85_RS03395	COG2188	Transcriptional regulator
B2J85_RS03400	COG1739	Uncharacterized protein family UPF0029
B2J85_RS03410	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS03415	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B2J85_RS03430	COG0653	protein targeting
B2J85_RS03435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B2J85_RS03440	COG2884	Cell division ATP-binding protein ftsE
B2J85_RS03445	COG2177	Part of the ABC transporter FtsEX involved in
B2J85_RS03460	COG0573	inorganic phosphate transmembrane transporter activity
B2J85_RS03465	COG0581	inorganic phosphate transmembrane transporter activity
B2J85_RS03470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B2J85_RS03475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B2J85_RS03480	COG0704	Plays a role in the regulation of phosphate uptake
B2J85_RS03495	COG1950	PFAM Membrane protein of
B2J85_RS03500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B2J85_RS03505	COG5002	protein histidine kinase activity
B2J85_RS03510	COG0745	RESPONSE REGULATOR receiver
B2J85_RS03535	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B2J85_RS03540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B2J85_RS03545	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B2J85_RS03550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2J85_RS03580	COG1609	Transcriptional regulator
B2J85_RS03600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B2J85_RS03610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B2J85_RS03615	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS03620	COG3763	UPF0154 protein
B2J85_RS03625	COG1737	Transcriptional regulator
B2J85_RS03635	COG0561	phosphatase activity
B2J85_RS03640	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS03645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2J85_RS03650	COG0640	Transcriptional regulator
B2J85_RS03660	COG0083	homoserine kinase activity
B2J85_RS03665	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B2J85_RS03670	COG0735	belongs to the Fur family
B2J85_RS03675	COG4536	flavin adenine dinucleotide binding
B2J85_RS03685	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B2J85_RS03690	COG1610	YqeY-like protein
B2J85_RS03695	COG1702	phosphate starvation-inducible protein PhoH
B2J85_RS03705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B2J85_RS03710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B2J85_RS03715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B2J85_RS03720	COG1381	Involved in DNA repair and RecF pathway recombination
B2J85_RS03725	COG0752	glycyl-tRNA synthetase alpha subunit
B2J85_RS03730	COG0751	glycine-tRNA ligase activity
B2J85_RS03745	COG1254	Belongs to the acylphosphatase family
B2J85_RS03750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2J85_RS03770	COG1686	Belongs to the peptidase S11 family
B2J85_RS03780	COG0673	inositol 2-dehydrogenase activity
B2J85_RS03785	COG0513	Belongs to the DEAD box helicase family
B2J85_RS03790	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS03790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS03795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS03800	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2J85_RS03840	COG1619	proteins homologs of microcin C7 resistance protein MccF
B2J85_RS03865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2J85_RS03885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B2J85_RS03905	COG2217	Heavy metal translocating P-type atpase
B2J85_RS03910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B2J85_RS03920	COG1278	Cold shock
B2J85_RS03930	COG1199	ATP-dependent helicase activity
B2J85_RS03930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B2J85_RS03940	COG0436	Aminotransferase
B2J85_RS03970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B2J85_RS03985	COG1215	transferase activity, transferring glycosyl groups
B2J85_RS03985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B2J85_RS04040	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B2J85_RS04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B2J85_RS04055	COG4585	Histidine kinase
B2J85_RS04060	COG2197	response regulator
B2J85_RS04065	COG0569	domain protein
B2J85_RS04070	COG4841	protein insertion into membrane
B2J85_RS04080	COG0463	Glycosyl transferase, family 2
B2J85_RS04090	COG5521	maltodextrose utilization protein MalA
B2J85_RS04095	COG2246	polysaccharide biosynthetic process
B2J85_RS04100	COG2246	polysaccharide biosynthetic process
B2J85_RS04105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B2J85_RS04115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B2J85_RS04120	COG1134	teichoic acid transport
B2J85_RS04125	COG1682	transport, permease protein
B2J85_RS04130	COG1316	TRANSCRIPTIONal
B2J85_RS04135	COG0768	penicillin binding
B2J85_RS04140	COG0488	(ABC) transporter
B2J85_RS04145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B2J85_RS04160	COG1272	protein, Hemolysin III
B2J85_RS04165	COG0371	Dehydrogenase
B2J85_RS04170	COG1307	EDD domain protein, DegV family
B2J85_RS04175	COG2755	lipolytic protein G-D-S-L family
B2J85_RS04180	COG4698	Protein conserved in bacteria
B2J85_RS04190	COG4479	Belongs to the UPF0346 family
B2J85_RS04195	COG0793	Belongs to the peptidase S41A family
B2J85_RS04195	COG3409	Peptidoglycan-binding domain 1 protein
B2J85_RS04200	COG0681	Belongs to the peptidase S26 family
B2J85_RS04205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B2J85_RS04245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B2J85_RS04250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B2J85_RS04255	COG0758	DNA mediated transformation
B2J85_RS04260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B2J85_RS04270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B2J85_RS04275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B2J85_RS04290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B2J85_RS04295	COG1832	CoA-binding protein
B2J85_RS04300	COG0187	DNA topoisomerase II activity
B2J85_RS04305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B2J85_RS04315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B2J85_RS04320	COG1227	inorganic diphosphatase activity
B2J85_RS04335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B2J85_RS04340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B2J85_RS04345	COG3385	transposase activity
B2J85_RS04370	COG0667	Aldo Keto reductase
B2J85_RS04385	COG0436	Aminotransferase
B2J85_RS04415	COG1876	peptidase activity
B2J85_RS04430	COG3275	phosphorelay sensor kinase activity
B2J85_RS04435	COG3279	Response regulator of the LytR AlgR family
B2J85_RS04440	COG1966	Carbon starvation protein
B2J85_RS04445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2J85_RS04450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B2J85_RS04455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B2J85_RS04460	COG4989	oxidoreductase activity
B2J85_RS04465	COG0516	GMP reductase activity
B2J85_RS04470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B2J85_RS04500	COG4476	Belongs to the UPF0223 family
B2J85_RS04505	COG0483	inositol monophosphate 1-phosphatase activity
B2J85_RS04510	COG1217	gtp-binding protein TYPA
B2J85_RS04515	COG4838	Belongs to the UPF0358 family
B2J85_RS04520	COG0772	Belongs to the SEDS family
B2J85_RS04525	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B2J85_RS04535	COG3679	Belongs to the UPF0342 family
B2J85_RS04540	COG4471	UPF0298 protein
B2J85_RS04545	COG0742	ribosomal rna small subunit methyltransferase
B2J85_RS04550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B2J85_RS04555	COG3480	Lon protease (S16) C-terminal proteolytic domain
B2J85_RS04575	COG2183	response to ionizing radiation
B2J85_RS04580	COG3091	SprT-like family
B2J85_RS04585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B2J85_RS04600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2J85_RS04600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2J85_RS04605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B2J85_RS04610	COG0237	dephospho-CoA kinase activity
B2J85_RS04615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B2J85_RS04625	COG1484	DNA-dependent DNA replication
B2J85_RS04630	COG2384	SAM-dependent methyltransferase
B2J85_RS04635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B2J85_RS04640	COG2195	Cleaves the N-terminal amino acid of tripeptides
B2J85_RS04650	COG0542	response to heat
B2J85_RS04655	COG0628	permease
B2J85_RS04665	COG0481	GTPase activity
B2J85_RS04685	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B2J85_RS04690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B2J85_RS04695	COG0402	S-adenosylhomocysteine deaminase activity
B2J85_RS04705	COG2365	Tyrosine phosphatase family
B2J85_RS04715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B2J85_RS04735	COG0544	peptidyl-prolyl cis-trans isomerase activity
B2J85_RS04740	COG3344	reverse transcriptase
B2J85_RS04750	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B2J85_RS04755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B2J85_RS04760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS04760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS04760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS04765	COG1105	Belongs to the carbohydrate kinase PfkB family
B2J85_RS04770	COG1349	DNA-binding transcription factor activity
B2J85_RS04775	COG0038	chloride channel
B2J85_RS04780	COG0210	DNA helicase
B2J85_RS04785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B2J85_RS04790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2J85_RS04795	COG0154	amidase activity
B2J85_RS04800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B2J85_RS04810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B2J85_RS04815	COG0702	epimerase
B2J85_RS04825	COG0519	Catalyzes the synthesis of GMP from XMP
B2J85_RS04830	COG0765	amino acid transport
B2J85_RS04835	COG1126	abc transporter atp-binding protein
B2J85_RS04840	COG0436	Aminotransferase
B2J85_RS04850	COG1596	polysaccharide export
B2J85_RS04850	COG1555	photosystem II stabilization
B2J85_RS04855	COG2131	deaminase
B2J85_RS04860	COG0658	competence protein
B2J85_RS04860	COG2333	competence protein COMEC
B2J85_RS04865	COG1466	dna polymerase III delta subunit
B2J85_RS04870	COG0268	Binds directly to 16S ribosomal RNA
B2J85_RS04880	COG0306	phosphate transporter
B2J85_RS04885	COG1392	Phosphate transport regulator
B2J85_RS04890	COG1968	undecaprenyl-diphosphatase activity
B2J85_RS04900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B2J85_RS04905	COG1199	ATP-dependent helicase activity
B2J85_RS04910	COG2151	metal-sulfur cluster biosynthetic enzyme
B2J85_RS04945	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2J85_RS04960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B2J85_RS04975	COG1388	LysM domain
B2J85_RS04995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B2J85_RS05010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B2J85_RS05020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B2J85_RS05025	COG0456	acetyltransferase
B2J85_RS05045	COG2124	cytochrome p450
B2J85_RS05050	COG1307	EDD domain protein, DegV family
B2J85_RS05060	COG0077	Prephenate dehydratase
B2J85_RS05065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B2J85_RS05075	COG0287	Prephenate dehydrogenase
B2J85_RS05080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B2J85_RS05085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B2J85_RS05090	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B2J85_RS05095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B2J85_RS05105	COG4120	Belongs to the binding-protein-dependent transport system permease family
B2J85_RS05120	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B2J85_RS05135	COG0284	orotidine-5'-phosphate decarboxylase activity
B2J85_RS05140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B2J85_RS05145	COG0505	Belongs to the CarA family
B2J85_RS05150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B2J85_RS05155	COG0540	Belongs to the ATCase OTCase family
B2J85_RS05170	COG0564	pseudouridine synthase activity
B2J85_RS05175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B2J85_RS05185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B2J85_RS05195	COG0328	RNA-DNA hybrid ribonuclease activity
B2J85_RS05210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B2J85_RS05225	COG0513	Belongs to the DEAD box helicase family
B2J85_RS05235	COG1418	mRNA catabolic process
B2J85_RS05240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B2J85_RS05255	COG1028	Short-chain dehydrogenase reductase Sdr
B2J85_RS05265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B2J85_RS05275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2J85_RS05300	COG0116	Belongs to the methyltransferase superfamily
B2J85_RS05310	COG3599	regulation of cell shape
B2J85_RS05315	COG4474	Belongs to the UPF0398 family
B2J85_RS05320	COG3331	DNA recombination
B2J85_RS05325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2J85_RS05330	COG3344	reverse transcriptase
B2J85_RS05335	COG3935	DnaD domain protein
B2J85_RS05340	COG0735	belongs to the Fur family
B2J85_RS05345	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2J85_RS05345	COG1388	LysM domain
B2J85_RS05355	COG4224	UPF0291 protein
B2J85_RS05360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B2J85_RS05370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2J85_RS05375	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B2J85_RS05375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B2J85_RS05380	COG5416	Lipopolysaccharide assembly protein A domain
B2J85_RS05385	COG0300	oxidoreductase activity
B2J85_RS05390	COG1234	tRNA 3'-trailer cleavage
B2J85_RS05400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B2J85_RS05415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B2J85_RS05420	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B2J85_RS05425	COG0668	transmembrane transport
B2J85_RS05430	COG0517	IMP dehydrogenase activity
B2J85_RS05440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B2J85_RS05445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B2J85_RS05455	COG0765	amino acid transport
B2J85_RS05460	COG0765	amino acid transport
B2J85_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2J85_RS05470	COG1126	abc transporter atp-binding protein
B2J85_RS05475	COG0180	Tryptophanyl-tRNA synthetase
B2J85_RS05480	COG0072	phenylalanine-tRNA ligase activity
B2J85_RS05480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2J85_RS05485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B2J85_RS05490	COG1733	regulation of RNA biosynthetic process
B2J85_RS05495	COG1074	ATP-dependent DNA helicase activity
B2J85_RS05500	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B2J85_RS05530	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B2J85_RS05540	COG1481	regulation of sporulation
B2J85_RS05545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B2J85_RS05550	COG1660	Displays ATPase and GTPase activities
B2J85_RS05555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B2J85_RS05560	COG0556	nucleotide-excision repair
B2J85_RS05565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2J85_RS05570	COG1126	abc transporter atp-binding protein
B2J85_RS05595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2J85_RS05615	COG0196	riboflavin kinase activity
B2J85_RS05620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B2J85_RS05625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B2J85_RS05640	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B2J85_RS05645	COG0195	Participates in both transcription termination and antitermination
B2J85_RS05650	COG0779	Required for maturation of 30S ribosomal subunits
B2J85_RS05655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B2J85_RS05670	COG3189	MarR family transcriptional regulator
B2J85_RS05695	COG3973	AAA domain
B2J85_RS05710	COG0475	glutathione-regulated potassium exporter activity
B2J85_RS05710	COG0569	domain protein
B2J85_RS05720	COG0217	transcriptional regulatory protein
B2J85_RS05725	COG1323	Belongs to the UPF0348 family
B2J85_RS05730	COG2226	methyltransferase
B2J85_RS05735	COG0799	negative regulation of ribosome biogenesis
B2J85_RS05740	COG1713	HD superfamily hydrolase involved in NAD metabolism
B2J85_RS05745	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B2J85_RS05750	COG1534	Rna-binding protein
B2J85_RS05755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B2J85_RS05760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B2J85_RS05785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2J85_RS05790	COG2096	Adenosyltransferase
B2J85_RS05805	COG0165	Argininosuccinate lyase
B2J85_RS05810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2J85_RS05825	COG2217	Heavy metal translocating P-type atpase
B2J85_RS05835	COG1737	Transcriptional regulator
B2J85_RS05840	COG1486	melibiose metabolic process
B2J85_RS05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS05845	COG1263	PTS System
B2J85_RS05865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS05870	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS05885	COG4166	transmembrane transport
B2J85_RS05890	COG1394	ATPase activity, coupled to movement of substances
B2J85_RS05895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS05895	COG2190	(PTS) system
B2J85_RS05895	COG1263	PTS System
B2J85_RS05915	COG0673	inositol 2-dehydrogenase activity
B2J85_RS05955	COG0366	Alpha amylase catalytic
B2J85_RS05965	COG1609	Transcriptional regulator
B2J85_RS05970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS05970	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS05980	COG3716	PTS system mannose fructose sorbose family IID component
B2J85_RS05985	COG3715	PTS system
B2J85_RS06005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2J85_RS06025	COG3711	transcriptional antiterminator
B2J85_RS06060	COG0366	Alpha amylase catalytic
B2J85_RS06065	COG1609	Transcriptional regulator
B2J85_RS06095	COG0277	FAD linked oxidase domain protein
B2J85_RS06100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06120	COG1129	ABC transporter
B2J85_RS06135	COG0583	DNA-binding transcription factor activity
B2J85_RS06140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2J85_RS06165	COG3716	PTS system mannose fructose sorbose family IID component
B2J85_RS06180	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS06200	COG3684	Belongs to the aldolase LacD family
B2J85_RS06205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS06205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS06205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS06210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS06210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS06210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2J85_RS06230	COG1063	alcohol dehydrogenase
B2J85_RS06235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B2J85_RS06245	COG0673	inositol 2-dehydrogenase activity
B2J85_RS06250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B2J85_RS06265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
B2J85_RS06270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS06290	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS06300	COG1609	Transcriptional regulator
B2J85_RS06305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06320	COG1929	Belongs to the glycerate kinase type-1 family
B2J85_RS06325	COG2610	gluconate transmembrane transporter activity
B2J85_RS06330	COG0425	Belongs to the sulfur carrier protein TusA family
B2J85_RS06345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B2J85_RS06365	COG0802	atpase or kinase
B2J85_RS06370	COG0280	phosphate acetyltransferase
B2J85_RS06375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B2J85_RS06380	COG0561	phosphatase activity
B2J85_RS06395	COG1780	Probably involved in ribonucleotide reductase function
B2J85_RS06400	COG0583	DNA-binding transcription factor activity
B2J85_RS06405	COG1368	sulfuric ester hydrolase activity
B2J85_RS06410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B2J85_RS06415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B2J85_RS06440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B2J85_RS06455	COG5002	protein histidine kinase activity
B2J85_RS06460	COG0745	RESPONSE REGULATOR receiver
B2J85_RS06485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B2J85_RS06490	COG3385	transposase activity
B2J85_RS06515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B2J85_RS06570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06585	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2J85_RS06590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS06595	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS06600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS06600	COG3711	transcriptional antiterminator
B2J85_RS06605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2J85_RS06610	COG1063	alcohol dehydrogenase
B2J85_RS06620	COG0604	alcohol dehydrogenase
B2J85_RS06645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2J85_RS06650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B2J85_RS06680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2J85_RS06685	COG2169	Transcriptional regulator
B2J85_RS06690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B2J85_RS06700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2J85_RS06705	COG1464	Belongs to the NlpA lipoprotein family
B2J85_RS06710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B2J85_RS06715	COG2130	NADP-dependent
B2J85_RS06725	COG1902	pentaerythritol trinitrate reductase activity
B2J85_RS06730	COG1733	regulation of RNA biosynthetic process
B2J85_RS06735	COG1136	(ABC) transporter
B2J85_RS06755	COG5002	protein histidine kinase activity
B2J85_RS06760	COG0745	RESPONSE REGULATOR receiver
B2J85_RS06770	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B2J85_RS06785	COG0167	dihydroorotate dehydrogenase activity
B2J85_RS06785	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B2J85_RS06790	COG0493	'glutamate synthase
B2J85_RS06840	COG0604	alcohol dehydrogenase
B2J85_RS06850	COG0640	Transcriptional regulator
B2J85_RS06860	COG4106	trans-aconitate 2-methyltransferase activity
B2J85_RS06880	COG0366	Alpha amylase catalytic
B2J85_RS06895	COG0583	DNA-binding transcription factor activity
B2J85_RS06945	COG2390	Transcriptional regulator
B2J85_RS06970	COG0254	rRNA binding
B2J85_RS06975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B2J85_RS06980	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B2J85_RS06990	COG0504	CTP synthase activity
B2J85_RS07000	COG0789	Transcriptional regulator
B2J85_RS07005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B2J85_RS07010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B2J85_RS07015	COG0584	glycerophosphoryl diester phosphodiesterase
B2J85_RS07025	COG0740	serine-type endopeptidase activity
B2J85_RS07030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B2J85_RS07040	COG1132	(ABC) transporter
B2J85_RS07050	COG5503	Protein of unknown function (DUF1447)
B2J85_RS07060	COG1278	Cold shock
B2J85_RS07065	COG2003	Belongs to the UPF0758 family
B2J85_RS07070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2J85_RS07075	COG0285	dihydrofolate synthase activity
B2J85_RS07080	COG0525	valine-tRNA ligase activity
B2J85_RS07085	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B2J85_RS07090	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B2J85_RS07095	COG0301	tRNA thio-modification
B2J85_RS07100	COG1104	cysteine desulfurase activity
B2J85_RS07105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B2J85_RS07115	COG3344	reverse transcriptase
B2J85_RS07120	COG4166	transmembrane transport
B2J85_RS07125	COG4876	unkown
B2J85_RS07135	COG0561	phosphatase activity
B2J85_RS07140	COG1801	Protein of unknown function DUF72
B2J85_RS07160	COG1823	symporter activity
B2J85_RS07165	COG2814	Major facilitator Superfamily
B2J85_RS07185	COG3579	cysteine-type endopeptidase activity
B2J85_RS07190	COG3594	Acyltransferase
B2J85_RS07220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B2J85_RS07245	COG1917	Cupin 2, conserved barrel domain protein
B2J85_RS07245	COG2207	Transcriptional regulator
B2J85_RS07250	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS07255	COG0640	Transcriptional regulator
B2J85_RS07260	COG2814	Major facilitator Superfamily
B2J85_RS07275	COG0693	protein deglycase activity
B2J85_RS07280	COG2217	Heavy metal translocating P-type atpase
B2J85_RS07295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2J85_RS07300	COG0783	Belongs to the Dps family
B2J85_RS07385	COG1098	S1 RNA binding domain
B2J85_RS07390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B2J85_RS07400	COG0492	ferredoxin-NADP+ reductase activity
B2J85_RS07405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2J85_RS07410	COG0477	Major facilitator Superfamily
B2J85_RS07415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2J85_RS07420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2J85_RS07425	COG1120	ATPase activity
B2J85_RS07430	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B2J85_RS07435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS07445	COG2233	PERMEase
B2J85_RS07450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2J85_RS07455	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B2J85_RS07460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2J85_RS07465	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS07465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS07470	COG2222	sugar isomerase
B2J85_RS07475	COG3716	PTS system mannose fructose sorbose family IID component
B2J85_RS07480	COG3715	PTS system
B2J85_RS07495	COG0235	Class ii aldolase
B2J85_RS07505	COG3775	system Galactitol-specific IIC component
B2J85_RS07510	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS07515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07520	COG3711	transcriptional antiterminator
B2J85_RS07550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07560	COG3711	transcriptional antiterminator
B2J85_RS07560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07565	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
B2J85_RS07570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS07570	COG1263	PTS System
B2J85_RS07575	COG1486	melibiose metabolic process
B2J85_RS07580	COG1737	Transcriptional regulator
B2J85_RS07590	COG2610	gluconate transmembrane transporter activity
B2J85_RS07605	COG0698	ribose 5-phosphate isomerase
B2J85_RS07615	COG1349	DNA-binding transcription factor activity
B2J85_RS07625	COG1461	Dihydroxyacetone kinase
B2J85_RS07630	COG2376	Dihydroxyacetone kinase
B2J85_RS07635	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B2J85_RS07640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B2J85_RS07645	COG1063	alcohol dehydrogenase
B2J85_RS07650	COG1454	alcohol dehydrogenase
B2J85_RS07650	COG1012	belongs to the aldehyde dehydrogenase family
B2J85_RS07670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B2J85_RS07675	COG4297	protein containing double-stranded beta helix domain
B2J85_RS07685	COG2271	Major facilitator Superfamily
B2J85_RS07695	COG0657	acetylesterase activity
B2J85_RS07695	COG2755	lipolytic protein G-D-S-L family
B2J85_RS07700	COG2390	Transcriptional regulator
B2J85_RS07705	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B2J85_RS07710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B2J85_RS07725	COG0549	Belongs to the carbamate kinase family
B2J85_RS07740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07740	COG3711	transcriptional antiterminator
B2J85_RS07745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS07750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS07755	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS07760	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2J85_RS07770	COG1929	Belongs to the glycerate kinase type-1 family
B2J85_RS07775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2J85_RS07780	COG4948	Mandelate Racemase Muconate Lactonizing
B2J85_RS07785	COG2084	Dehydrogenase
B2J85_RS07790	COG2721	sulfolactate sulfo-lyase activity
B2J85_RS07795	COG2610	gluconate transmembrane transporter activity
B2J85_RS07810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B2J85_RS07825	COG2217	Heavy metal translocating P-type atpase
B2J85_RS07835	COG1131	(ABC) transporter
B2J85_RS07840	COG1131	(ABC) transporter
B2J85_RS07855	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS07860	COG2190	(PTS) system
B2J85_RS07860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS07860	COG1263	PTS System
B2J85_RS07885	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B2J85_RS07915	COG1914	H( )-stimulated, divalent metal cation uptake system
B2J85_RS07920	COG1472	Belongs to the glycosyl hydrolase 3 family
B2J85_RS07925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B2J85_RS07940	COG3711	transcriptional antiterminator
B2J85_RS07940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07945	COG4821	SIS domain
B2J85_RS07965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS07965	COG3711	transcriptional antiterminator
B2J85_RS07970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS07970	COG1263	PTS System
B2J85_RS07980	COG1486	melibiose metabolic process
B2J85_RS07985	COG1737	Transcriptional regulator
B2J85_RS08000	COG2059	Chromate
B2J85_RS08020	COG3715	PTS system
B2J85_RS08025	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS08025	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS08035	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS08035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS08040	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS08040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS08045	COG0668	transmembrane transport
B2J85_RS08060	COG1953	Uracil, thiamine, allantoin
B2J85_RS08075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B2J85_RS08080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2J85_RS08090	COG1461	Dihydroxyacetone kinase
B2J85_RS08095	COG2376	Dihydroxyacetone kinase
B2J85_RS08115	COG0405	Gamma-glutamyltransferase
B2J85_RS08130	COG2188	Transcriptional regulator
B2J85_RS08135	COG2190	(PTS) system
B2J85_RS08135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS08135	COG1263	PTS System
B2J85_RS08140	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS08155	COG1472	Belongs to the glycosyl hydrolase 3 family
B2J85_RS08180	COG0318	PFAM AMP-dependent synthetase and ligase
B2J85_RS08185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B2J85_RS08190	COG2050	protein possibly involved in aromatic compounds catabolism
B2J85_RS08205	COG1869	D-ribose catabolic process
B2J85_RS08230	COG2814	Major facilitator Superfamily
B2J85_RS08235	COG2801	Transposase and inactivated derivatives
B2J85_RS08250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS08250	COG3711	transcriptional antiterminator
B2J85_RS08255	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS08260	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2J85_RS08265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS08275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS08295	COG2017	converts alpha-aldose to the beta-anomer
B2J85_RS08305	COG2814	Major facilitator Superfamily
B2J85_RS08305	COG0477	Major facilitator Superfamily
B2J85_RS08310	COG1070	Carbohydrate kinase
B2J85_RS08325	COG1879	ABC-type sugar transport system periplasmic component
B2J85_RS08330	COG1172	Belongs to the binding-protein-dependent transport system permease family
B2J85_RS08335	COG1129	ABC transporter
B2J85_RS08340	COG1869	D-ribose catabolic process
B2J85_RS08345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B2J85_RS08350	COG1609	Transcriptional regulator
B2J85_RS08355	COG2957	Belongs to the agmatine deiminase family
B2J85_RS08365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B2J85_RS08385	COG1609	Transcriptional regulator
B2J85_RS08390	COG2017	converts alpha-aldose to the beta-anomer
B2J85_RS08400	COG2160	L-arabinose isomerase activity
B2J85_RS08435	COG1454	alcohol dehydrogenase
B2J85_RS08440	COG1012	belongs to the aldehyde dehydrogenase family
B2J85_RS08445	COG1510	regulation of RNA biosynthetic process
B2J85_RS08450	COG2113	Glycine betaine
B2J85_RS08490	COG2188	Transcriptional regulator
B2J85_RS08500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2J85_RS08505	COG0783	Belongs to the Dps family
B2J85_RS08515	COG2217	Heavy metal translocating P-type atpase
B2J85_RS08530	COG0582	viral genome integration into host DNA
B2J85_RS08545	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
B2J85_RS08605	COG2217	Heavy metal translocating P-type atpase
B2J85_RS08625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2J85_RS08630	COG0783	Belongs to the Dps family
B2J85_RS08635	COG3328	transposase activity
B2J85_RS08645	COG0390	transport system, permease component
B2J85_RS08650	COG4619	ABC transporter
B2J85_RS08655	COG0662	Cupin 2, conserved barrel domain protein
B2J85_RS08680	COG2213	PTS system mannitol-specific
B2J85_RS08695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2J85_RS08700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS08705	COG1349	DNA-binding transcription factor activity
B2J85_RS08725	COG2160	L-arabinose isomerase activity
B2J85_RS08740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2J85_RS08745	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B2J85_RS08750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS08755	COG0517	IMP dehydrogenase activity
B2J85_RS08755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2J85_RS08765	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS08770	COG3775	system Galactitol-specific IIC component
B2J85_RS08780	COG3711	transcriptional antiterminator
B2J85_RS08790	COG0517	IMP dehydrogenase activity
B2J85_RS08790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B2J85_RS08800	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS08805	COG3775	system Galactitol-specific IIC component
B2J85_RS08810	COG0698	ribose 5-phosphate isomerase
B2J85_RS08855	COG3177	Filamentation induced by cAMP protein fic
B2J85_RS08890	COG2002	toxin-antitoxin pair type II binding
B2J85_RS08945	COG1937	Protein conserved in bacteria
B2J85_RS08950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2J85_RS08955	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2J85_RS08975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B2J85_RS09055	COG1567	CRISPR-associated RAMP protein, Csm4 family
B2J85_RS09060	COG1337	RAMP superfamily
B2J85_RS09105	COG0210	DNA helicase
B2J85_RS09110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B2J85_RS09130	COG3385	transposase activity
B2J85_RS09165	COG1442	glycosyl transferase family 8
B2J85_RS09165	COG1216	Glycosyl transferase, family 2
B2J85_RS09175	COG0438	transferase activity, transferring glycosyl groups
B2J85_RS09195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B2J85_RS09200	COG4464	protein tyrosine phosphatase activity
B2J85_RS09205	COG0489	protein tyrosine kinase activity
B2J85_RS09215	COG1316	TRANSCRIPTIONal
B2J85_RS09230	COG3764	Sortase (surface protein transpeptidase)
B2J85_RS09245	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2J85_RS09245	COG3942	CHAP domain
B2J85_RS09250	COG0628	permease
B2J85_RS09255	COG0716	FMN binding
B2J85_RS09270	COG2249	NAD(P)H dehydrogenase (quinone) activity
B2J85_RS09300	COG2261	transglycosylase associated protein
B2J85_RS09305	COG5039	Polysaccharide pyruvyl transferase
B2J85_RS09310	COG5039	Polysaccharide pyruvyl transferase
B2J85_RS09325	COG4175	Glycine betaine
B2J85_RS09325	COG3448	diguanylate cyclase activity
B2J85_RS09355	COG1472	Belongs to the glycosyl hydrolase 3 family
B2J85_RS09360	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B2J85_RS09365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B2J85_RS09370	COG1288	antiporter activity
B2J85_RS09390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B2J85_RS09395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B2J85_RS09400	COG0084	hydrolase, TatD family'
B2J85_RS09405	COG1408	metallophosphoesterase
B2J85_RS09440	COG1053	succinate dehydrogenase
B2J85_RS09445	COG1082	Xylose isomerase domain protein TIM barrel
B2J85_RS09450	COG0531	amino acid
B2J85_RS09460	COG3001	Fructosamine kinase
B2J85_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
B2J85_RS09475	COG3344	reverse transcriptase
B2J85_RS09485	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B2J85_RS09490	COG4109	DRTGG domain
B2J85_RS09495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B2J85_RS09500	COG0363	glucosamine-6-phosphate deaminase activity
B2J85_RS09505	COG0246	Mannitol dehydrogenase
B2J85_RS09510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2J85_RS09515	COG3711	transcriptional antiterminator
B2J85_RS09520	COG2213	PTS system mannitol-specific
B2J85_RS09530	COG0471	metal ion transport
B2J85_RS09540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B2J85_RS09545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B2J85_RS09560	COG3448	diguanylate cyclase activity
B2J85_RS09560	COG4175	Glycine betaine
B2J85_RS09565	COG2188	Transcriptional regulator
B2J85_RS09590	COG3344	reverse transcriptase
B2J85_RS09615	COG0367	asparagine synthase
B2J85_RS09635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B2J85_RS09645	COG1136	(ABC) transporter
B2J85_RS09645	COG0577	efflux transmembrane transporter activity
B2J85_RS09645	COG1136	(ABC) transporter
B2J85_RS09645	COG0577	efflux transmembrane transporter activity
B2J85_RS09650	COG0488	(ABC) transporter
B2J85_RS09660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B2J85_RS09665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B2J85_RS09670	COG1695	Transcriptional regulator
B2J85_RS09680	COG1940	carbohydrate kinase activity
B2J85_RS09705	COG1054	Belongs to the UPF0176 family
B2J85_RS09710	COG1073	alpha beta
B2J85_RS09715	COG1394	ATPase activity, coupled to movement of substances
B2J85_RS09720	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
B2J85_RS09725	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
B2J85_RS09735	COG1527	subunit (C
B2J85_RS09740	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
B2J85_RS09745	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2J85_RS09750	COG1269	ATP hydrolysis coupled proton transport
B2J85_RS09765	COG1285	pathogenesis
B2J85_RS09775	COG2217	Heavy metal translocating P-type atpase
B2J85_RS09785	COG0702	epimerase
B2J85_RS09800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B2J85_RS09815	COG3716	PTS system mannose fructose sorbose family IID component
B2J85_RS09820	COG3715	PTS system
B2J85_RS09835	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B2J85_RS09835	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B2J85_RS09845	COG2222	sugar isomerase
B2J85_RS09850	COG2188	Transcriptional regulator
B2J85_RS09855	COG3684	Belongs to the aldolase LacD family
B2J85_RS09860	COG1063	alcohol dehydrogenase
B2J85_RS09865	COG3775	system Galactitol-specific IIC component
B2J85_RS09870	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS09880	COG1349	DNA-binding transcription factor activity
B2J85_RS09895	COG1461	Dihydroxyacetone kinase
B2J85_RS09900	COG2376	Dihydroxyacetone kinase
B2J85_RS09905	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
B2J85_RS09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2J85_RS09920	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B2J85_RS09930	COG3118	belongs to the thioredoxin family
B2J85_RS09935	COG0386	Belongs to the glutathione peroxidase family
B2J85_RS09940	COG1846	Transcriptional regulator
B2J85_RS09945	COG0492	ferredoxin-NADP+ reductase activity
B2J85_RS09965	COG0322	excinuclease ABC activity
B2J85_RS09980	COG3711	transcriptional antiterminator
B2J85_RS09985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B2J85_RS09995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B2J85_RS10000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2J85_RS10005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2J85_RS10010	COG0589	response to stress
B2J85_RS10015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2J85_RS10020	COG1363	Peptidase, m42
B2J85_RS10040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B2J85_RS10045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B2J85_RS10075	COG4537	Required for transformation and DNA binding
B2J85_RS10080	COG1459	type II secretion system
B2J85_RS10085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B2J85_RS10090	COG2755	lipolytic protein G-D-S-L family
B2J85_RS10090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B2J85_RS10095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2J85_RS10100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B2J85_RS10105	COG0124	histidyl-tRNA synthetase
B2J85_RS10110	COG0824	Thioesterase
B2J85_RS10125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B2J85_RS10130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B2J85_RS10135	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B2J85_RS10140	COG4166	transmembrane transport
B2J85_RS10145	COG2508	Transcriptional regulator
B2J85_RS10150	COG0402	S-adenosylhomocysteine deaminase activity
B2J85_RS10155	COG0402	S-adenosylhomocysteine deaminase activity
B2J85_RS10160	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2J85_RS10165	COG1428	Deoxynucleoside kinase
B2J85_RS10170	COG0083	homoserine kinase activity
B2J85_RS10185	COG1304	FMN binding
B2J85_RS10195	COG0343	queuine tRNA-ribosyltransferase activity
B2J85_RS10210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B2J85_RS10235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B2J85_RS10245	COG2337	Toxic component of a toxin-antitoxin (TA) module
B2J85_RS10250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B2J85_RS10255	COG0736	holo-[acyl-carrier-protein] synthase activity
B2J85_RS10265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B2J85_RS10270	COG1181	Belongs to the D-alanine--D-alanine ligase family
B2J85_RS10275	COG1671	Belongs to the UPF0178 family
B2J85_RS10290	COG3385	transposase activity
B2J85_RS10300	COG0572	uridine kinase
B2J85_RS10305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B2J85_RS10315	COG1393	Belongs to the ArsC family
B2J85_RS10320	COG0772	Belongs to the SEDS family
B2J85_RS10340	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B2J85_RS10345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B2J85_RS10350	COG0009	L-threonylcarbamoyladenylate synthase
B2J85_RS10355	COG2890	protein-(glutamine-N5) methyltransferase activity
B2J85_RS10360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B2J85_RS10365	COG1435	thymidine kinase activity
B2J85_RS10380	COG0071	Belongs to the small heat shock protein (HSP20) family
B2J85_RS10390	COG0681	Belongs to the peptidase S26 family
B2J85_RS10400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B2J85_RS10405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B2J85_RS10410	COG3442	glutamine amidotransferase
B2J85_RS10415	COG2190	(PTS) system
B2J85_RS10415	COG1263	PTS System
B2J85_RS10415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS10425	COG1482	cell wall glycoprotein biosynthetic process
B2J85_RS10440	COG0537	adenosine 5'-monophosphoramidase activity
B2J85_RS10450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B2J85_RS10455	COG3481	metal-dependent phosphohydrolase, HD sub domain
B2J85_RS10480	COG3383	formate dehydrogenase (NAD+) activity
B2J85_RS10495	COG2116	formate transmembrane transporter activity
B2J85_RS10500	COG0746	molybdenum cofactor guanylyltransferase activity
B2J85_RS10535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B2J85_RS10550	COG0315	cyclic pyranopterin monophosphate synthase activity
B2J85_RS10555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B2J85_RS10560	COG3679	Belongs to the UPF0342 family
B2J85_RS10565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2J85_RS10570	COG0564	pseudouridine synthase activity
B2J85_RS10575	COG1187	pseudouridine synthase activity
B2J85_RS10580	COG2244	polysaccharide biosynthetic process
B2J85_RS10585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B2J85_RS10595	COG1764	response to oxidative stress
B2J85_RS10600	COG0495	leucyl-tRNA aminoacylation
B2J85_RS10605	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2J85_RS10605	COG1388	LysM domain
B2J85_RS10610	COG0671	phosphoesterase, PA-phosphatase related
B2J85_RS10615	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B2J85_RS10635	COG3775	system Galactitol-specific IIC component
B2J85_RS10640	COG3414	Phosphotransferase system galactitol-specific IIB component
B2J85_RS10645	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B2J85_RS10650	COG0693	protein deglycase activity
B2J85_RS10660	COG0488	(ABC) transporter
B2J85_RS10665	COG1464	Belongs to the NlpA lipoprotein family
B2J85_RS10670	COG1028	Short-chain dehydrogenase reductase Sdr
B2J85_RS10680	COG2205	protein histidine kinase activity
B2J85_RS10695	COG0745	RESPONSE REGULATOR receiver
B2J85_RS10700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2J85_RS10705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B2J85_RS10730	COG4939	FMN-binding domain protein
B2J85_RS10745	COG0142	geranyltranstransferase activity
B2J85_RS10750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2J85_RS10755	COG0456	acetyltransferase
B2J85_RS10760	COG0826	peptidase U32
B2J85_RS10775	COG0542	response to heat
B2J85_RS10780	COG4463	regulation of RNA biosynthetic process
B2J85_RS10785	COG0515	serine threonine protein kinase
B2J85_RS10785	COG2815	serine threonine protein kinase
B2J85_RS10795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2J85_RS10795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2J85_RS10800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B2J85_RS10805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B2J85_RS10810	COG1758	RNA polymerase activity
B2J85_RS10815	COG0194	GDP metabolic process
B2J85_RS10835	COG0351	phosphomethylpyrimidine kinase
B2J85_RS10845	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B2J85_RS10865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B2J85_RS10870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B2J85_RS10875	COG0105	UTP biosynthetic process
B2J85_RS10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2J85_RS10885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B2J85_RS10890	COG1121	(ABC) transporter
B2J85_RS10895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B2J85_RS10910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B2J85_RS10915	COG2188	Transcriptional regulator
B2J85_RS10920	COG1418	mRNA catabolic process
B2J85_RS10925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B2J85_RS10930	COG1058	Belongs to the CinA family
B2J85_RS10930	COG1546	Belongs to the CinA family
B2J85_RS10935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B2J85_RS10940	COG1426	Protein conserved in bacteria
B2J85_RS10945	COG0612	Peptidase, M16
B2J85_RS10950	COG0612	Peptidase, M16
B2J85_RS10960	COG1970	mechanosensitive ion channel activity
B2J85_RS10965	COG4466	Protein conserved in bacteria
B2J85_RS10975	COG3688	RNA-binding protein containing a PIN domain
B2J85_RS10980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2J85_RS10985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B2J85_RS10990	COG0215	cysteine-tRNA ligase activity
B2J85_RS10995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B2J85_RS11000	COG4956	integral membrane protein (PIN domain superfamily)
B2J85_RS11010	COG0756	dUTP diphosphatase activity
B2J85_RS11015	COG0656	L-ascorbic acid biosynthetic process
B2J85_RS11020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B2J85_RS11025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B2J85_RS11035	COG0488	(ABC) transporter
B2J85_RS11045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B2J85_RS11050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
B2J85_RS11055	COG0305	Participates in initiation and elongation during chromosome replication
B2J85_RS11060	COG0359	binds to the 23S rRNA
B2J85_RS11070	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B2J85_RS11080	COG0360	Binds together with S18 to 16S ribosomal RNA
B2J85_RS11090	COG0187	DNA topoisomerase II activity
B2J85_RS11095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B2J85_RS11105	COG0592	DNA-directed DNA polymerase activity
B2J85_RS11110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B2J85_RS11120	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B2J85_RS11125	COG0594	ribonuclease P activity
B2J85_RS11130	COG0706	membrane insertase activity
B2J85_RS11145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B2J85_RS11150	COG0445	tRNA wobble uridine modification
B2J85_RS11155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2J85_RS11175	COG1380	Effector of murein hydrolase LrgA
B2J85_RS11185	COG1304	FMN binding
B2J85_RS11190	COG3385	transposase activity
B2J85_RS11210	COG0798	PFAM Bile acid sodium symporter
B2J85_RS11230	COG1442	glycosyl transferase family 8
B2J85_RS11250	COG0357	Ribosomal RNA small subunit methyltransferase G
B2J85_RS11255	COG1192	Involved in chromosome partitioning
B2J85_RS11260	COG1475	DNA binding
B2J85_RS11265	COG4481	Protein conserved in bacteria
B2J85_RS11270	COG0012	GTP binding
B2J85_RS11280	COG0517	IMP dehydrogenase activity
B2J85_RS11280	COG0516	GMP reductase activity
B2J85_RS11285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B2J85_RS11360	COG1162	GTPase activity
B2J85_RS11365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B2J85_RS11395	COG0783	Belongs to the Dps family
B2J85_RS11400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B2J85_RS11405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B2J85_RS11410	COG2267	carboxylic ester hydrolase activity
B2J85_RS11430	COG1349	DNA-binding transcription factor activity
B2J85_RS11465	COG3684	Belongs to the aldolase LacD family
B2J85_RS11475	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2J85_RS11480	COG2723	6-phospho-beta-galactosidase activity
B2J85_RS11485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS11485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2J85_RS11490	COG1438	arginine binding
B2J85_RS11495	COG1438	arginine binding
B2J85_RS11500	COG2235	arginine
B2J85_RS11505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B2J85_RS11510	COG0549	Belongs to the carbamate kinase family
B2J85_RS11515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2J85_RS11520	COG1288	antiporter activity
B2J85_RS11525	COG1846	Transcriptional regulator
B2J85_RS11540	COG2153	protein acetylation
B2J85_RS11545	COG0018	arginyl-trna synthetase
B2J85_RS11555	COG4975	Glucose uptake
B2J85_RS11570	COG1271	oxidase subunit
B2J85_RS11575	COG1294	oxidase, subunit
B2J85_RS11580	COG4988	ABC transporter
B2J85_RS11585	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B2J85_RS11595	COG3443	Belongs to the bacterial solute-binding protein 9 family
B2J85_RS11595	COG0803	Belongs to the bacterial solute-binding protein 9 family
B2J85_RS11605	COG4166	transmembrane transport
B2J85_RS11625	COG1252	NADH dehydrogenase
B2J85_RS11635	COG2814	Major facilitator Superfamily
B2J85_RS11645	COG1012	belongs to the aldehyde dehydrogenase family
B2J85_RS11655	COG0217	transcriptional regulatory protein
B2J85_RS11665	COG0039	L-malate dehydrogenase activity
B2J85_RS11670	COG0193	aminoacyl-tRNA hydrolase activity
B2J85_RS11675	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B2J85_RS11680	COG2244	polysaccharide biosynthetic process
B2J85_RS11685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B2J85_RS11695	COG1098	S1 RNA binding domain
B2J85_RS11700	COG0037	tRNA processing
B2J85_RS11705	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B2J85_RS11715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B2J85_RS11720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B2J85_RS11870	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B2J85_RS11905	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B2J85_RS11910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS11910	COG1263	PTS System
B2J85_RS11920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B2J85_RS11925	COG1737	Transcriptional regulator
B2J85_RS11930	COG0039	L-malate dehydrogenase activity
B2J85_RS11935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B2J85_RS11940	COG0517	IMP dehydrogenase activity
B2J85_RS11945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2J85_RS11945	COG0574	Belongs to the PEP-utilizing enzyme family
B2J85_RS11970	COG1309	transcriptional regulator
B2J85_RS11980	COG1309	transcriptional regulator
B2J85_RS11985	COG2409	Drug exporters of the RND superfamily
B2J85_RS11985	COG1033	growth of symbiont in host cell
B2J85_RS12015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B2J85_RS12020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B2J85_RS12025	COG0435	Glutathione S-transferase
B2J85_RS12030	COG0714	Associated with various cellular activities
B2J85_RS12040	COG1305	Transglutaminase-like
B2J85_RS12045	COG2340	Cysteine-rich secretory protein family
B2J85_RS12055	COG1263	PTS System
B2J85_RS12055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2J85_RS12055	COG2190	(PTS) system
B2J85_RS12060	COG1388	LysM domain
B2J85_RS12065	COG1968	undecaprenyl-diphosphatase activity
B2J85_RS12070	COG0471	metal ion transport
B2J85_RS12075	COG0473	3-isopropylmalate dehydrogenase activity
B2J85_RS12090	COG1388	LysM domain
B2J85_RS12100	COG1286	toxin biosynthetic process
B2J85_RS12105	COG0789	Transcriptional regulator
B2J85_RS12115	COG2267	carboxylic ester hydrolase activity
B2J85_RS12125	COG1694	Mazg nucleotide pyrophosphohydrolase
B2J85_RS12135	COG0693	protein deglycase activity
B2J85_RS12140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B2J85_RS12145	COG0625	glutathione transferase activity
B2J85_RS12150	COG0765	amino acid transport
B2J85_RS12155	COG1126	abc transporter atp-binding protein
B2J85_RS12165	COG0561	phosphatase activity
B2J85_RS12170	COG0471	metal ion transport
B2J85_RS12175	COG0628	permease
B2J85_RS12180	COG0708	Exodeoxyribonuclease III
B2J85_RS12185	COG1181	Belongs to the D-alanine--D-alanine ligase family
B2J85_RS12190	COG3385	transposase activity
B2J85_RS12195	COG0640	Transcriptional regulator
B2J85_RS12220	COG3344	reverse transcriptase
B2J85_RS12230	COG3576	pyridoxamine 5-phosphate
B2J85_RS12290	COG3385	transposase activity
B2J85_RS12310	COG1114	Component of the transport system for branched-chain amino acids
B2J85_RS12325	COG1396	sequence-specific DNA binding
B2J85_RS12335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B2J85_RS12335	COG0519	Catalyzes the synthesis of GMP from XMP
B2J85_RS12340	COG1072	(Pantothenic acid kinase))
B2J85_RS12345	COG2813	Specifically methylates the guanine in position
B2J85_RS12350	COG1609	Transcriptional regulator
B2J85_RS12355	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B2J85_RS12360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B2J85_RS12365	COG0295	cytidine deaminase activity
B2J85_RS12370	COG1744	ABC transporter substrate-binding protein PnrA-like
B2J85_RS12375	COG3845	ABC transporter
B2J85_RS12380	COG4603	Belongs to the binding-protein-dependent transport system permease family
B2J85_RS12385	COG1079	Belongs to the binding-protein-dependent transport system permease family
B2J85_RS12395	COG0813	purine-nucleoside phosphorylase activity
B2J85_RS12405	COG1979	alcohol dehydrogenase
B2J85_RS12410	COG0588	phosphoglycerate mutase activity
B2J85_RS12415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B2J85_RS12420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B2J85_RS12425	COG0049	tRNA binding
B2J85_RS12430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B2J85_RS12435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B2J85_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2J85_RS12455	COG0051	transcription antitermination factor activity, RNA binding
B2J85_RS12460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B2J85_RS12465	COG0088	Forms part of the polypeptide exit tunnel
B2J85_RS12470	COG0089	rRNA binding
B2J85_RS12475	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B2J85_RS12480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B2J85_RS12485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B2J85_RS12490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B2J85_RS12500	COG0255	Belongs to the universal ribosomal protein uL29 family
B2J85_RS12505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B2J85_RS12510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B2J85_RS12515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B2J85_RS12520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B2J85_RS12525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B2J85_RS12530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B2J85_RS12535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B2J85_RS12540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B2J85_RS12545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B2J85_RS12550	COG1841	ribosomal large subunit assembly
B2J85_RS12555	COG0200	Binds to the 23S rRNA
B2J85_RS12565	COG0563	adenylate kinase activity
B2J85_RS12570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B2J85_RS12575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B2J85_RS12580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B2J85_RS12585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B2J85_RS12590	COG0202	RNA polymerase activity
B2J85_RS12595	COG0203	ribosomal protein L17
B2J85_RS12600	COG1122	ATPase activity
B2J85_RS12605	COG1122	ATPase activity
B2J85_RS12615	COG0101	tRNA pseudouridine synthase activity
B2J85_RS12620	COG0174	glutamine synthetase
B2J85_RS12625	COG4485	Bacterial membrane protein, YfhO
B2J85_RS12660	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B2J85_RS12665	COG3385	transposase activity