locus-tag	class	description
C7H83_RS00010	COG0589	response to stress
C7H83_RS00015	COG3344	reverse transcriptase
C7H83_RS00025	COG0561	phosphatase activity
C7H83_RS00030	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS00040	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS00045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7H83_RS00055	COG4473	ABC transporter
C7H83_RS00060	COG1131	(ABC) transporter
C7H83_RS00065	COG1132	(ABC) transporter
C7H83_RS00080	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7H83_RS00085	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7H83_RS00095	COG4149	molybdate abc transporter
C7H83_RS00110	COG0242	peptide deformylase activity
C7H83_RS00115	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS00120	COG2011	ABC-type metal ion transport system permease component
C7H83_RS00125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7H83_RS00130	COG0110	maltose O-acetyltransferase activity
C7H83_RS00145	COG0765	amino acid transport
C7H83_RS00150	COG1126	abc transporter atp-binding protein
C7H83_RS00155	COG1114	Component of the transport system for branched-chain amino acids
C7H83_RS00165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7H83_RS00170	COG2255	four-way junction helicase activity
C7H83_RS00200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7H83_RS00205	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7H83_RS00210	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7H83_RS00215	COG1692	metallophosphoesterase
C7H83_RS00230	COG0561	phosphatase activity
C7H83_RS00240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7H83_RS00255	COG3279	Response regulator of the LytR AlgR family
C7H83_RS00265	COG1268	BioY protein
C7H83_RS00270	COG4493	Belongs to the UPF0637 family
C7H83_RS00295	COG2918	glutathione biosynthetic process
C7H83_RS00295	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_RS00315	COG0552	protein localization to endoplasmic reticulum
C7H83_RS00320	COG0561	phosphatase activity
C7H83_RS00325	COG1196	nuclear chromosome segregation
C7H83_RS00330	COG0571	ribonuclease III activity
C7H83_RS00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7H83_RS00340	COG0416	fatty acid biosynthetic process
C7H83_RS00345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7H83_RS00350	COG1461	Dihydroxyacetone kinase
C7H83_RS00360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7H83_RS00380	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7H83_RS00420	COG4485	Bacterial membrane protein, YfhO
C7H83_RS00425	COG0174	glutamine synthetase
C7H83_RS00430	COG3344	reverse transcriptase
C7H83_RS00435	COG0101	tRNA pseudouridine synthase activity
C7H83_RS00445	COG1122	ATPase activity
C7H83_RS00450	COG1122	ATPase activity
C7H83_RS00455	COG0203	ribosomal protein L17
C7H83_RS00460	COG0202	RNA polymerase activity
C7H83_RS00465	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7H83_RS00470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7H83_RS00475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7H83_RS00480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7H83_RS00485	COG0563	adenylate kinase activity
C7H83_RS00495	COG0200	Binds to the 23S rRNA
C7H83_RS00500	COG1841	ribosomal large subunit assembly
C7H83_RS00505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7H83_RS00510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7H83_RS00515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7H83_RS00520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7H83_RS00525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7H83_RS00530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7H83_RS00535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7H83_RS00540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7H83_RS00545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7H83_RS00550	COG0255	Belongs to the universal ribosomal protein uL29 family
C7H83_RS00560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7H83_RS00565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7H83_RS00570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7H83_RS00575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7H83_RS00580	COG0089	rRNA binding
C7H83_RS00585	COG0088	Forms part of the polypeptide exit tunnel
C7H83_RS00590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7H83_RS00595	COG0051	transcription antitermination factor activity, RNA binding
C7H83_RS00610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7H83_RS00615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7H83_RS00620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7H83_RS00625	COG0049	tRNA binding
C7H83_RS00630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7H83_RS00640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7H83_RS00645	COG0588	phosphoglycerate mutase activity
C7H83_RS00650	COG1979	alcohol dehydrogenase
C7H83_RS00660	COG0813	purine-nucleoside phosphorylase activity
C7H83_RS00670	COG1079	Belongs to the binding-protein-dependent transport system permease family
C7H83_RS00675	COG4603	Belongs to the binding-protein-dependent transport system permease family
C7H83_RS00680	COG3845	ABC transporter
C7H83_RS00685	COG1744	ABC transporter substrate-binding protein PnrA-like
C7H83_RS00690	COG0295	cytidine deaminase activity
C7H83_RS00695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_RS00705	COG1609	Transcriptional regulator
C7H83_RS00710	COG2813	Specifically methylates the guanine in position
C7H83_RS00715	COG1072	(Pantothenic acid kinase))
C7H83_RS00720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7H83_RS00720	COG0519	Catalyzes the synthesis of GMP from XMP
C7H83_RS00725	COG3344	reverse transcriptase
C7H83_RS00745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7H83_RS00790	COG1396	sequence-specific DNA binding
C7H83_RS00855	COG1104	cysteine desulfurase activity
C7H83_RS00860	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C7H83_RS00865	COG0709	Synthesizes selenophosphate from selenide and ATP
C7H83_RS00875	COG0640	Transcriptional regulator
C7H83_RS00880	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_RS00885	COG0708	Exodeoxyribonuclease III
C7H83_RS00890	COG0628	permease
C7H83_RS00910	COG0561	phosphatase activity
C7H83_RS00920	COG1126	abc transporter atp-binding protein
C7H83_RS00945	COG2197	response regulator
C7H83_RS00950	COG4585	Histidine kinase
C7H83_RS00955	COG1968	undecaprenyl-diphosphatase activity
C7H83_RS00960	COG1388	LysM domain
C7H83_RS00975	COG2340	Cysteine-rich secretory protein family
C7H83_RS00980	COG1305	Transglutaminase-like
C7H83_RS00990	COG0714	Associated with various cellular activities
C7H83_RS00995	COG0435	Glutathione S-transferase
C7H83_RS01005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7H83_RS01010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7H83_RS01035	COG1136	(ABC) transporter
C7H83_RS01035	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7H83_RS01040	COG1309	transcriptional regulator
C7H83_RS01065	COG0574	Belongs to the PEP-utilizing enzyme family
C7H83_RS01065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7H83_RS01070	COG0517	IMP dehydrogenase activity
C7H83_RS01075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7H83_RS01080	COG0039	L-malate dehydrogenase activity
C7H83_RS01085	COG1737	Transcriptional regulator
C7H83_RS01090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7H83_RS01100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS01100	COG1263	PTS System
C7H83_RS01105	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7H83_RS01120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7H83_RS01270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7H83_RS01275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7H83_RS01285	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C7H83_RS01290	COG0037	tRNA processing
C7H83_RS01295	COG1098	S1 RNA binding domain
C7H83_RS01305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7H83_RS01310	COG2244	polysaccharide biosynthetic process
C7H83_RS01315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7H83_RS01320	COG0193	aminoacyl-tRNA hydrolase activity
C7H83_RS01325	COG0039	L-malate dehydrogenase activity
C7H83_RS01335	COG0217	transcriptional regulatory protein
C7H83_RS01345	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_RS01355	COG2814	Major facilitator Superfamily
C7H83_RS01390	COG4166	transmembrane transport
C7H83_RS01400	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7H83_RS01400	COG3443	Belongs to the bacterial solute-binding protein 9 family
C7H83_RS01410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7H83_RS01415	COG4988	ABC transporter
C7H83_RS01420	COG1294	oxidase, subunit
C7H83_RS01425	COG1271	oxidase subunit
C7H83_RS01440	COG4975	Glucose uptake
C7H83_RS01450	COG0018	arginyl-trna synthetase
C7H83_RS01460	COG2235	arginine
C7H83_RS01465	COG1438	arginine binding
C7H83_RS01470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS01470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS01475	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS01480	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_RS01485	COG3684	Belongs to the aldolase LacD family
C7H83_RS01520	COG1349	DNA-binding transcription factor activity
C7H83_RS01535	COG2267	carboxylic ester hydrolase activity
C7H83_RS01540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7H83_RS01545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7H83_RS01550	COG0783	Belongs to the Dps family
C7H83_RS01580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_RS01585	COG1162	GTPase activity
C7H83_RS01660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7H83_RS01665	COG0516	GMP reductase activity
C7H83_RS01665	COG0517	IMP dehydrogenase activity
C7H83_RS01675	COG0012	GTP binding
C7H83_RS01680	COG4481	Protein conserved in bacteria
C7H83_RS01685	COG1475	DNA binding
C7H83_RS01690	COG1192	Involved in chromosome partitioning
C7H83_RS01695	COG0357	Ribosomal RNA small subunit methyltransferase G
C7H83_RS01720	COG1442	glycosyl transferase family 8
C7H83_RS01750	COG1304	FMN binding
C7H83_RS01760	COG1380	Effector of murein hydrolase LrgA
C7H83_RS01785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7H83_RS01790	COG0445	tRNA wobble uridine modification
C7H83_RS01795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7H83_RS01810	COG0706	membrane insertase activity
C7H83_RS01815	COG0594	ribonuclease P activity
C7H83_RS01820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7H83_RS01830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7H83_RS01835	COG0592	DNA-directed DNA polymerase activity
C7H83_RS01840	COG2501	S4 domain
C7H83_RS01845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7H83_RS01850	COG0187	DNA topoisomerase II activity
C7H83_RS01860	COG0360	Binds together with S18 to 16S ribosomal RNA
C7H83_RS01870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7H83_RS01880	COG0359	binds to the 23S rRNA
C7H83_RS01885	COG0305	Participates in initiation and elongation during chromosome replication
C7H83_RS01890	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C7H83_RS01895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7H83_RS01905	COG0488	(ABC) transporter
C7H83_RS01920	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7H83_RS01925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7H83_RS01935	COG3949	Membrane
C7H83_RS01940	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS01945	COG0756	dUTP diphosphatase activity
C7H83_RS01955	COG4956	integral membrane protein (PIN domain superfamily)
C7H83_RS01960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7H83_RS01965	COG0215	cysteine-tRNA ligase activity
C7H83_RS01970	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7H83_RS01975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7H83_RS01980	COG3688	RNA-binding protein containing a PIN domain
C7H83_RS01990	COG4466	Protein conserved in bacteria
C7H83_RS01995	COG1970	mechanosensitive ion channel activity
C7H83_RS02000	COG0612	Peptidase, M16
C7H83_RS02005	COG0612	Peptidase, M16
C7H83_RS02010	COG1426	Protein conserved in bacteria
C7H83_RS02015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7H83_RS02020	COG1058	Belongs to the CinA family
C7H83_RS02020	COG1546	Belongs to the CinA family
C7H83_RS02025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7H83_RS02030	COG1418	mRNA catabolic process
C7H83_RS02035	COG2188	Transcriptional regulator
C7H83_RS02040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_RS02045	COG1554	hydrolase, family 65, central catalytic
C7H83_RS02050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS02050	COG1263	PTS System
C7H83_RS02055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7H83_RS02060	COG1121	(ABC) transporter
C7H83_RS02065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7H83_RS02070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_RS02075	COG0105	UTP biosynthetic process
C7H83_RS02080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7H83_RS02085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7H83_RS02100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7H83_RS02110	COG0351	phosphomethylpyrimidine kinase
C7H83_RS02125	COG4443	Transcriptional Coactivator p15 (PC4)
C7H83_RS02130	COG0194	GDP metabolic process
C7H83_RS02135	COG1758	RNA polymerase activity
C7H83_RS02140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7H83_RS02145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7H83_RS02150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7H83_RS02150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7H83_RS02160	COG2815	serine threonine protein kinase
C7H83_RS02160	COG0515	serine threonine protein kinase
C7H83_RS02165	COG4463	regulation of RNA biosynthetic process
C7H83_RS02170	COG0542	response to heat
C7H83_RS02185	COG0826	peptidase U32
C7H83_RS02190	COG0456	acetyltransferase
C7H83_RS02195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_RS02200	COG0142	geranyltranstransferase activity
C7H83_RS02215	COG4939	FMN-binding domain protein
C7H83_RS02240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7H83_RS02245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_RS02250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_RS02255	COG0745	RESPONSE REGULATOR receiver
C7H83_RS02270	COG2205	protein histidine kinase activity
C7H83_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS02285	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS02290	COG0488	(ABC) transporter
C7H83_RS02300	COG0693	protein deglycase activity
C7H83_RS02305	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7H83_RS02310	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_RS02315	COG3775	system Galactitol-specific IIC component
C7H83_RS02335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7H83_RS02340	COG0671	phosphoesterase, PA-phosphatase related
C7H83_RS02345	COG1388	LysM domain
C7H83_RS02345	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_RS02350	COG0495	leucyl-tRNA aminoacylation
C7H83_RS02355	COG1764	response to oxidative stress
C7H83_RS02365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7H83_RS02370	COG2244	polysaccharide biosynthetic process
C7H83_RS02375	COG1187	pseudouridine synthase activity
C7H83_RS02380	COG0564	pseudouridine synthase activity
C7H83_RS02385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_RS02390	COG3679	Belongs to the UPF0342 family
C7H83_RS02395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7H83_RS02415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7H83_RS02420	COG0746	molybdenum cofactor guanylyltransferase activity
C7H83_RS02425	COG2116	formate transmembrane transporter activity
C7H83_RS02445	COG3383	formate dehydrogenase (NAD+) activity
C7H83_RS02475	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7H83_RS02480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7H83_RS02490	COG0537	adenosine 5'-monophosphoramidase activity
C7H83_RS02505	COG1482	cell wall glycoprotein biosynthetic process
C7H83_RS02515	COG1263	PTS System
C7H83_RS02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS02515	COG2190	(PTS) system
C7H83_RS02520	COG3442	glutamine amidotransferase
C7H83_RS02525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7H83_RS02530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7H83_RS02535	COG0681	Belongs to the peptidase S26 family
C7H83_RS02540	COG0514	ATP-dependent DNA helicase (RecQ)
C7H83_RS02545	COG0071	Belongs to the small heat shock protein (HSP20) family
C7H83_RS02560	COG1435	thymidine kinase activity
C7H83_RS02565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7H83_RS02570	COG2890	protein-(glutamine-N5) methyltransferase activity
C7H83_RS02575	COG0009	L-threonylcarbamoyladenylate synthase
C7H83_RS02580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7H83_RS02585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7H83_RS02600	COG0772	Belongs to the SEDS family
C7H83_RS02615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7H83_RS02620	COG0572	uridine kinase
C7H83_RS02635	COG1671	Belongs to the UPF0178 family
C7H83_RS02640	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7H83_RS02645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7H83_RS02655	COG0736	holo-[acyl-carrier-protein] synthase activity
C7H83_RS02660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7H83_RS02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7H83_RS02675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7H83_RS02700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7H83_RS02710	COG0343	queuine tRNA-ribosyltransferase activity
C7H83_RS02720	COG1304	FMN binding
C7H83_RS02735	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7H83_RS02740	COG1428	Deoxynucleoside kinase
C7H83_RS02745	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_RS02750	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_RS02755	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_RS02760	COG2508	Transcriptional regulator
C7H83_RS02765	COG4166	transmembrane transport
C7H83_RS02770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7H83_RS02775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7H83_RS02780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7H83_RS02795	COG0824	Thioesterase
C7H83_RS02800	COG0124	histidyl-tRNA synthetase
C7H83_RS02805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7H83_RS02810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_RS02815	COG2755	lipolytic protein G-D-S-L family
C7H83_RS02815	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7H83_RS02820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7H83_RS02825	COG1459	type II secretion system
C7H83_RS02830	COG4537	Required for transformation and DNA binding
C7H83_RS02860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7H83_RS02865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7H83_RS02885	COG1363	Peptidase, m42
C7H83_RS02890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7H83_RS02895	COG0589	response to stress
C7H83_RS02900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_RS02905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7H83_RS02910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7H83_RS02915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7H83_RS02920	COG3711	transcriptional antiterminator
C7H83_RS02935	COG0322	excinuclease ABC activity
C7H83_RS02960	COG0492	ferredoxin-NADP+ reductase activity
C7H83_RS02965	COG1846	Transcriptional regulator
C7H83_RS02970	COG0386	Belongs to the glutathione peroxidase family
C7H83_RS02975	COG3118	belongs to the thioredoxin family
C7H83_RS02985	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
C7H83_RS02990	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_RS02995	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7H83_RS03000	COG2376	Dihydroxyacetone kinase
C7H83_RS03005	COG1461	Dihydroxyacetone kinase
C7H83_RS03030	COG2188	Transcriptional regulator
C7H83_RS03035	COG2222	sugar isomerase
C7H83_RS03045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7H83_RS03055	COG0702	epimerase
C7H83_RS03065	COG2217	Heavy metal translocating P-type atpase
C7H83_RS03070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_RS03070	COG0425	Belongs to the sulfur carrier protein TusA family
C7H83_RS03075	COG1285	pathogenesis
C7H83_RS03090	COG1269	ATP hydrolysis coupled proton transport
C7H83_RS03095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_RS03100	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
C7H83_RS03105	COG1527	subunit (C
C7H83_RS03115	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
C7H83_RS03120	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
C7H83_RS03125	COG1394	ATPase activity, coupled to movement of substances
C7H83_RS03130	COG1073	alpha beta
C7H83_RS03135	COG1054	Belongs to the UPF0176 family
C7H83_RS03165	COG1940	carbohydrate kinase activity
C7H83_RS03175	COG1695	Transcriptional regulator
C7H83_RS03180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7H83_RS03185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7H83_RS03210	COG1136	(ABC) transporter
C7H83_RS03210	COG0577	efflux transmembrane transporter activity
C7H83_RS03210	COG1136	(ABC) transporter
C7H83_RS03210	COG0577	efflux transmembrane transporter activity
C7H83_RS03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7H83_RS03240	COG0367	asparagine synthase
C7H83_RS03265	COG3344	reverse transcriptase
C7H83_RS03290	COG2188	Transcriptional regulator
C7H83_RS03295	COG4175	Glycine betaine
C7H83_RS03295	COG3448	diguanylate cyclase activity
C7H83_RS03320	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7H83_RS03325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7H83_RS03330	COG0471	metal ion transport
C7H83_RS03350	COG0363	glucosamine-6-phosphate deaminase activity
C7H83_RS03355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7H83_RS03360	COG4109	DRTGG domain
C7H83_RS03365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7H83_RS03380	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS03385	COG3001	Fructosamine kinase
C7H83_RS03395	COG0531	amino acid
C7H83_RS03400	COG1082	Xylose isomerase domain protein TIM barrel
C7H83_RS03405	COG1053	succinate dehydrogenase
C7H83_RS03435	COG1408	metallophosphoesterase
C7H83_RS03440	COG0084	hydrolase, TatD family'
C7H83_RS03445	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7H83_RS03450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7H83_RS03465	COG3385	transposase activity
C7H83_RS03480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7H83_RS03485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7H83_RS03490	COG1472	Belongs to the glycosyl hydrolase 3 family
C7H83_RS03515	COG3448	diguanylate cyclase activity
C7H83_RS03515	COG4175	Glycine betaine
C7H83_RS03525	COG5039	Polysaccharide pyruvyl transferase
C7H83_RS03530	COG5039	Polysaccharide pyruvyl transferase
C7H83_RS03535	COG2261	transglycosylase associated protein
C7H83_RS03545	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7H83_RS03560	COG0716	FMN binding
C7H83_RS03565	COG0628	permease
C7H83_RS03570	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_RS03570	COG3942	CHAP domain
C7H83_RS03585	COG1316	TRANSCRIPTIONal
C7H83_RS03595	COG0489	protein tyrosine kinase activity
C7H83_RS03600	COG4464	protein tyrosine phosphatase activity
C7H83_RS03610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7H83_RS03635	COG0463	Glycosyl transferase, family 2
C7H83_RS03635	COG1216	Glycosyl transferase, family 2
C7H83_RS03640	COG0438	transferase activity, transferring glycosyl groups
C7H83_RS03715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS03725	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS03730	COG1105	Belongs to the carbohydrate kinase PfkB family
C7H83_RS03735	COG1349	DNA-binding transcription factor activity
C7H83_RS03745	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_RS03810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7H83_RS03825	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_RS03830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_RS03835	COG1937	Protein conserved in bacteria
C7H83_RS03980	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_RS03985	COG3775	system Galactitol-specific IIC component
C7H83_RS04005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS04015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS04020	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS04025	COG0300	oxidoreductase activity
C7H83_RS04050	COG0662	Cupin 2, conserved barrel domain protein
C7H83_RS04055	COG4619	ABC transporter
C7H83_RS04060	COG0390	transport system, permease component
C7H83_RS04075	COG0783	Belongs to the Dps family
C7H83_RS04080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_RS04090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_RS04140	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7H83_RS04145	COG0783	Belongs to the Dps family
C7H83_RS04150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_RS04155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_RS04230	COG0582	viral genome integration into host DNA
C7H83_RS04265	COG2050	protein possibly involved in aromatic compounds catabolism
C7H83_RS04270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7H83_RS04275	COG0318	PFAM AMP-dependent synthetase and ligase
C7H83_RS04295	COG2113	Glycine betaine
C7H83_RS04300	COG1510	regulation of RNA biosynthetic process
C7H83_RS04305	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_RS04310	COG1454	alcohol dehydrogenase
C7H83_RS04340	COG2814	Major facilitator Superfamily
C7H83_RS04360	COG4975	Glucose uptake
C7H83_RS04365	COG1869	D-ribose catabolic process
C7H83_RS04375	COG2017	converts alpha-aldose to the beta-anomer
C7H83_RS04380	COG2814	Major facilitator Superfamily
C7H83_RS04400	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS04405	COG2190	(PTS) system
C7H83_RS04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS04405	COG1263	PTS System
C7H83_RS04410	COG2188	Transcriptional regulator
C7H83_RS04440	COG2376	Dihydroxyacetone kinase
C7H83_RS04445	COG1461	Dihydroxyacetone kinase
C7H83_RS04455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7H83_RS04460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7H83_RS04470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7H83_RS04475	COG2252	PERMEase
C7H83_RS04480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7H83_RS04495	COG1263	PTS System
C7H83_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS04510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7H83_RS04530	COG1744	ABC transporter substrate-binding protein PnrA-like
C7H83_RS04555	COG4989	oxidoreductase activity
C7H83_RS04560	COG3284	Transcriptional regulator
C7H83_RS04565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_RS04575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7H83_RS04580	COG0022	dehydrogenase e1 component
C7H83_RS04585	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7H83_RS04595	COG2217	Heavy metal translocating P-type atpase
C7H83_RS04605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS04605	COG1263	PTS System
C7H83_RS04610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7H83_RS04615	COG1737	Transcriptional regulator
C7H83_RS04625	COG0383	alpha-mannosidase activity
C7H83_RS04655	COG0738	Major facilitator superfamily
C7H83_RS04665	COG1609	Transcriptional regulator
C7H83_RS04680	COG3069	C4-dicarboxylate transmembrane transporter activity
C7H83_RS04690	COG2188	Transcriptional regulator
C7H83_RS04700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7H83_RS04705	COG2873	o-acetylhomoserine
C7H83_RS04725	COG0549	Belongs to the carbamate kinase family
C7H83_RS04740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_RS04745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7H83_RS04750	COG2390	Transcriptional regulator
C7H83_RS04755	COG0657	acetylesterase activity
C7H83_RS04755	COG2755	lipolytic protein G-D-S-L family
C7H83_RS04775	COG2271	Major facilitator Superfamily
C7H83_RS04785	COG4297	protein containing double-stranded beta helix domain
C7H83_RS04790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7H83_RS04810	COG1454	alcohol dehydrogenase
C7H83_RS04810	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_RS04815	COG1063	alcohol dehydrogenase
C7H83_RS04820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7H83_RS04825	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7H83_RS04830	COG2376	Dihydroxyacetone kinase
C7H83_RS04835	COG1461	Dihydroxyacetone kinase
C7H83_RS04845	COG1349	DNA-binding transcription factor activity
C7H83_RS04855	COG0698	ribose 5-phosphate isomerase
C7H83_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS04880	COG0800	Aldolase
C7H83_RS04885	COG2610	gluconate transmembrane transporter activity
C7H83_RS04890	COG2186	Transcriptional regulator
C7H83_RS04900	COG1737	Transcriptional regulator
C7H83_RS04905	COG1486	melibiose metabolic process
C7H83_RS04910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS04910	COG1263	PTS System
C7H83_RS04915	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7H83_RS04925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS04925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS04930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C7H83_RS04940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS04940	COG3711	transcriptional antiterminator
C7H83_RS04950	COG3730	PTS system glucitol sorbitol-specific
C7H83_RS04960	COG3732	PTS system glucitol sorbitol-specific
C7H83_RS04975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_RS04980	COG2233	PERMEase
C7H83_RS04990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_RS04995	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7H83_RS05000	COG1120	ATPase activity
C7H83_RS05005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7H83_RS05010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7H83_RS05015	COG0477	Major facilitator Superfamily
C7H83_RS05020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7H83_RS05025	COG0492	ferredoxin-NADP+ reductase activity
C7H83_RS05035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7H83_RS05040	COG1098	S1 RNA binding domain
C7H83_RS05120	COG0783	Belongs to the Dps family
C7H83_RS05125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_RS05140	COG2217	Heavy metal translocating P-type atpase
C7H83_RS05150	COG0693	protein deglycase activity
C7H83_RS05160	COG2814	Major facilitator Superfamily
C7H83_RS05165	COG0640	Transcriptional regulator
C7H83_RS05175	COG2207	Transcriptional regulator
C7H83_RS05175	COG1917	Cupin 2, conserved barrel domain protein
C7H83_RS05205	COG2826	transposase and inactivated derivatives, IS30 family
C7H83_RS05225	COG0667	Aldo Keto reductase
C7H83_RS05235	COG1979	alcohol dehydrogenase
C7H83_RS05255	COG0789	Transcriptional regulator
C7H83_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS05280	COG4221	oxidoreductase activity
C7H83_RS05285	COG0789	Transcriptional regulator
C7H83_RS05305	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS05310	COG0789	Transcriptional regulator
C7H83_RS05350	COG0798	PFAM Bile acid sodium symporter
C7H83_RS05370	COG5002	protein histidine kinase activity
C7H83_RS05375	COG0745	RESPONSE REGULATOR receiver
C7H83_RS05400	COG1309	transcriptional regulator
C7H83_RS05410	COG2814	Major facilitator Superfamily
C7H83_RS05415	COG0640	Transcriptional regulator
C7H83_RS05440	COG3385	transposase activity
C7H83_RS05445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7H83_RS05455	COG0559	Belongs to the binding-protein-dependent transport system permease family
C7H83_RS05475	COG0516	GMP reductase activity
C7H83_RS05475	COG0517	IMP dehydrogenase activity
C7H83_RS05485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7H83_RS05490	COG1902	pentaerythritol trinitrate reductase activity
C7H83_RS05505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7H83_RS05510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7H83_RS05540	COG3594	Acyltransferase
C7H83_RS05545	COG3579	cysteine-type endopeptidase activity
C7H83_RS05560	COG2814	Major facilitator Superfamily
C7H83_RS05570	COG1823	symporter activity
C7H83_RS05585	COG1801	Protein of unknown function DUF72
C7H83_RS05590	COG0561	phosphatase activity
C7H83_RS05600	COG4876	unkown
C7H83_RS05605	COG4166	transmembrane transport
C7H83_RS05615	COG0527	aspartate kinase activity
C7H83_RS05620	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7H83_RS05625	COG1104	cysteine desulfurase activity
C7H83_RS05630	COG0301	tRNA thio-modification
C7H83_RS05635	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7H83_RS05640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7H83_RS05650	COG0525	valine-tRNA ligase activity
C7H83_RS05655	COG0285	dihydrofolate synthase activity
C7H83_RS05660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7H83_RS05665	COG2003	Belongs to the UPF0758 family
C7H83_RS05670	COG1278	Cold shock
C7H83_RS05680	COG5503	Protein of unknown function (DUF1447)
C7H83_RS05695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7H83_RS05700	COG0745	RESPONSE REGULATOR receiver
C7H83_RS05705	COG5002	protein histidine kinase activity
C7H83_RS05705	COG3850	Histidine kinase
C7H83_RS05720	COG0740	serine-type endopeptidase activity
C7H83_RS05730	COG0584	glycerophosphoryl diester phosphodiesterase
C7H83_RS05735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7H83_RS05740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7H83_RS05745	COG0789	Transcriptional regulator
C7H83_RS05755	COG0504	CTP synthase activity
C7H83_RS05765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7H83_RS05770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7H83_RS05775	COG0254	rRNA binding
C7H83_RS05800	COG2390	Transcriptional regulator
C7H83_RS05825	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7H83_RS05855	COG0745	RESPONSE REGULATOR receiver
C7H83_RS05860	COG5002	protein histidine kinase activity
C7H83_RS05880	COG1136	(ABC) transporter
C7H83_RS05900	COG1725	Transcriptional regulator
C7H83_RS05905	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7H83_RS05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7H83_RS05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7H83_RS05920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7H83_RS05925	COG0131	Imidazoleglycerol-phosphate dehydratase
C7H83_RS05930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7H83_RS05935	COG0107	imidazoleglycerol-phosphate synthase activity
C7H83_RS05940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7H83_RS05940	COG0140	phosphoribosyl-ATP diphosphatase activity
C7H83_RS05955	COG3339	Conserved Protein
C7H83_RS05970	COG0352	thiamine-phosphate diphosphorylase activity
C7H83_RS05975	COG0351	phosphomethylpyrimidine kinase
C7H83_RS06000	COG1473	amidohydrolase
C7H83_RS06005	COG1473	amidohydrolase
C7H83_RS06010	COG0601	transmembrane transport
C7H83_RS06015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7H83_RS06025	COG0444	Belongs to the ABC transporter superfamily
C7H83_RS06030	COG4608	Belongs to the ABC transporter superfamily
C7H83_RS06040	COG1733	regulation of RNA biosynthetic process
C7H83_RS06045	COG1902	pentaerythritol trinitrate reductase activity
C7H83_RS06060	COG2130	NADP-dependent
C7H83_RS06070	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS06075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7H83_RS06090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_RS06095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7H83_RS06100	COG2169	Transcriptional regulator
C7H83_RS06105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_RS06115	COG0431	NADPH-dependent FMN reductase
C7H83_RS06125	COG3344	reverse transcriptase
C7H83_RS06130	COG0367	asparagine synthase
C7H83_RS06145	COG1595	DNA-templated transcription, initiation
C7H83_RS06155	COG1131	(ABC) transporter
C7H83_RS06180	COG3620	sequence-specific DNA binding
C7H83_RS06195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7H83_RS06200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7H83_RS06220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7H83_RS06235	COG3344	reverse transcriptase
C7H83_RS06240	COG0604	alcohol dehydrogenase
C7H83_RS06250	COG1063	alcohol dehydrogenase
C7H83_RS06255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7H83_RS06260	COG3711	transcriptional antiterminator
C7H83_RS06260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS06265	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS06275	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_RS06285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS06295	COG0561	phosphatase activity
C7H83_RS06325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7H83_RS06335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7H83_RS06340	COG0067	glutamate synthase
C7H83_RS06340	COG0069	glutamate synthase activity
C7H83_RS06340	COG0070	glutamate synthase
C7H83_RS06345	COG0493	'glutamate synthase
C7H83_RS06350	COG2826	transposase and inactivated derivatives, IS30 family
C7H83_RS06355	COG0004	ammonium transporteR
C7H83_RS06365	COG0583	DNA-binding transcription factor activity
C7H83_RS06390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7H83_RS06400	COG0789	Transcriptional regulator
C7H83_RS06405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7H83_RS06410	COG0531	amino acid
C7H83_RS06430	COG0745	RESPONSE REGULATOR receiver
C7H83_RS06435	COG5002	protein histidine kinase activity
C7H83_RS06450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7H83_RS06480	COG2188	Transcriptional regulator
C7H83_RS06485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS06490	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS06495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7H83_RS06500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7H83_RS06505	COG1368	sulfuric ester hydrolase activity
C7H83_RS06510	COG0583	DNA-binding transcription factor activity
C7H83_RS06515	COG1780	Probably involved in ribonucleotide reductase function
C7H83_RS06530	COG0561	phosphatase activity
C7H83_RS06535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7H83_RS06540	COG0280	phosphate acetyltransferase
C7H83_RS06545	COG0802	atpase or kinase
C7H83_RS06570	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS06590	COG3711	transcriptional antiterminator
C7H83_RS06595	COG1609	Transcriptional regulator
C7H83_RS06600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS06600	COG1263	PTS System
C7H83_RS06610	COG1621	beta-fructofuranosidase activity
C7H83_RS06630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7H83_RS06675	COG1403	HNH endonuclease
C7H83_RS06685	COG1783	phage Terminase large subunit
C7H83_RS06800	COG0582	viral genome integration into host DNA
C7H83_RS06825	COG1396	sequence-specific DNA binding
C7H83_RS06900	COG2610	gluconate transmembrane transporter activity
C7H83_RS06915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS06920	COG1609	Transcriptional regulator
C7H83_RS06930	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS06950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS06955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7H83_RS06970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7H83_RS07000	COG4975	Glucose uptake
C7H83_RS07010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7H83_RS07055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7H83_RS07060	COG0583	DNA-binding transcription factor activity
C7H83_RS07090	COG1129	ABC transporter
C7H83_RS07110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS07115	COG0277	FAD linked oxidase domain protein
C7H83_RS07145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7H83_RS07150	COG0366	Alpha amylase catalytic
C7H83_RS07180	COG3711	transcriptional antiterminator
C7H83_RS07200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7H83_RS07215	COG3715	PTS system
C7H83_RS07245	COG0673	inositol 2-dehydrogenase activity
C7H83_RS07265	COG1653	transport
C7H83_RS07270	COG1175	transmembrane transport
C7H83_RS07280	COG2190	(PTS) system
C7H83_RS07280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS07280	COG1263	PTS System
C7H83_RS07285	COG1394	ATPase activity, coupled to movement of substances
C7H83_RS07290	COG4166	transmembrane transport
C7H83_RS07305	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS07310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS07325	COG1263	PTS System
C7H83_RS07325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS07330	COG1486	melibiose metabolic process
C7H83_RS07335	COG1737	Transcriptional regulator
C7H83_RS07345	COG0165	Argininosuccinate lyase
C7H83_RS07360	COG2096	Adenosyltransferase
C7H83_RS07365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7H83_RS07390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7H83_RS07395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7H83_RS07400	COG1534	Rna-binding protein
C7H83_RS07405	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7H83_RS07410	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7H83_RS07415	COG0799	negative regulation of ribosome biogenesis
C7H83_RS07420	COG2226	methyltransferase
C7H83_RS07425	COG1323	Belongs to the UPF0348 family
C7H83_RS07430	COG0217	transcriptional regulatory protein
C7H83_RS07445	COG0475	glutathione-regulated potassium exporter activity
C7H83_RS07445	COG0569	domain protein
C7H83_RS07495	COG3189	MarR family transcriptional regulator
C7H83_RS07510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7H83_RS07515	COG0779	Required for maturation of 30S ribosomal subunits
C7H83_RS07520	COG0195	Participates in both transcription termination and antitermination
C7H83_RS07525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7H83_RS07540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7H83_RS07545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7H83_RS07550	COG0196	riboflavin kinase activity
C7H83_RS07570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7H83_RS07595	COG1126	abc transporter atp-binding protein
C7H83_RS07600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_RS07605	COG0556	nucleotide-excision repair
C7H83_RS07610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7H83_RS07615	COG1660	Displays ATPase and GTPase activities
C7H83_RS07620	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7H83_RS07625	COG1481	regulation of sporulation
C7H83_RS07635	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7H83_RS07645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7H83_RS07665	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7H83_RS07670	COG1074	ATP-dependent DNA helicase activity
C7H83_RS07675	COG1733	regulation of RNA biosynthetic process
C7H83_RS07680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7H83_RS07685	COG0072	phenylalanine-tRNA ligase activity
C7H83_RS07685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_RS07690	COG0180	Tryptophanyl-tRNA synthetase
C7H83_RS07695	COG1126	abc transporter atp-binding protein
C7H83_RS07700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_RS07705	COG0765	amino acid transport
C7H83_RS07710	COG0765	amino acid transport
C7H83_RS07715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7H83_RS07720	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7H83_RS07730	COG0517	IMP dehydrogenase activity
C7H83_RS07735	COG0668	transmembrane transport
C7H83_RS07740	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7H83_RS07745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7H83_RS07765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7H83_RS07775	COG1234	tRNA 3'-trailer cleavage
C7H83_RS07780	COG0300	oxidoreductase activity
C7H83_RS07785	COG5416	Lipopolysaccharide assembly protein A domain
C7H83_RS07790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7H83_RS07790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7H83_RS07795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_RS07820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7H83_RS07825	COG4224	UPF0291 protein
C7H83_RS07835	COG1388	LysM domain
C7H83_RS07835	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7H83_RS07840	COG0735	belongs to the Fur family
C7H83_RS07845	COG3935	DnaD domain protein
C7H83_RS07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_RS07855	COG3331	DNA recombination
C7H83_RS07860	COG4474	Belongs to the UPF0398 family
C7H83_RS07865	COG3599	regulation of cell shape
C7H83_RS07875	COG0116	Belongs to the methyltransferase superfamily
C7H83_RS07915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7H83_RS07920	COG2832	Protein of unknown function (DUF454)
C7H83_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS07945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7H83_RS07950	COG1418	mRNA catabolic process
C7H83_RS07960	COG0513	Belongs to the DEAD box helicase family
C7H83_RS07975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7H83_RS07990	COG0328	RNA-DNA hybrid ribonuclease activity
C7H83_RS08000	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7H83_RS08010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7H83_RS08015	COG0564	pseudouridine synthase activity
C7H83_RS08035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7H83_RS08040	COG0505	Belongs to the CarA family
C7H83_RS08045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7H83_RS08050	COG0284	orotidine-5'-phosphate decarboxylase activity
C7H83_RS08065	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7H83_RS08080	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7H83_RS08090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7H83_RS08095	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7H83_RS08100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7H83_RS08105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7H83_RS08110	COG0287	Prephenate dehydrogenase
C7H83_RS08120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7H83_RS08125	COG0077	Prephenate dehydratase
C7H83_RS08135	COG1307	EDD domain protein, DegV family
C7H83_RS08140	COG2124	cytochrome p450
C7H83_RS08165	COG0456	acetyltransferase
C7H83_RS08170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7H83_RS08180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7H83_RS08185	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_RS08190	COG0753	catalase activity
C7H83_RS08195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_RS08205	COG1012	belongs to the aldehyde dehydrogenase family
C7H83_RS08210	COG1388	LysM domain
C7H83_RS08225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7H83_RS08240	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7H83_RS08270	COG0167	dihydroorotate dehydrogenase activity
C7H83_RS08275	COG2151	metal-sulfur cluster biosynthetic enzyme
C7H83_RS08280	COG1199	ATP-dependent helicase activity
C7H83_RS08285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7H83_RS08295	COG1968	undecaprenyl-diphosphatase activity
C7H83_RS08300	COG1392	Phosphate transport regulator
C7H83_RS08305	COG0306	phosphate transporter
C7H83_RS08310	COG0268	Binds directly to 16S ribosomal RNA
C7H83_RS08315	COG1466	dna polymerase III delta subunit
C7H83_RS08320	COG2333	competence protein COMEC
C7H83_RS08320	COG0658	competence protein
C7H83_RS08325	COG2131	deaminase
C7H83_RS08330	COG1596	polysaccharide export
C7H83_RS08330	COG1555	photosystem II stabilization
C7H83_RS08340	COG0436	Aminotransferase
C7H83_RS08345	COG1126	abc transporter atp-binding protein
C7H83_RS08350	COG0765	amino acid transport
C7H83_RS08355	COG0519	Catalyzes the synthesis of GMP from XMP
C7H83_RS08365	COG0702	epimerase
C7H83_RS08370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7H83_RS08380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7H83_RS08385	COG0154	amidase activity
C7H83_RS08390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7H83_RS08395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7H83_RS08400	COG0210	DNA helicase
C7H83_RS08405	COG0038	chloride channel
C7H83_RS08410	COG1349	DNA-binding transcription factor activity
C7H83_RS08415	COG1105	Belongs to the carbohydrate kinase PfkB family
C7H83_RS08420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS08420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_RS08420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_RS08425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7H83_RS08430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7H83_RS08435	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7H83_RS08455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7H83_RS08465	COG2365	Tyrosine phosphatase family
C7H83_RS08480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7H83_RS08485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7H83_RS08505	COG0481	GTPase activity
C7H83_RS08515	COG0628	permease
C7H83_RS08520	COG0542	response to heat
C7H83_RS08530	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7H83_RS08535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7H83_RS08540	COG2384	SAM-dependent methyltransferase
C7H83_RS08545	COG1484	DNA-dependent DNA replication
C7H83_RS08555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7H83_RS08560	COG0237	dephospho-CoA kinase activity
C7H83_RS08565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7H83_RS08570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7H83_RS08570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7H83_RS08585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7H83_RS08590	COG3091	SprT-like family
C7H83_RS08595	COG2183	response to ionizing radiation
C7H83_RS08615	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7H83_RS08620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7H83_RS08625	COG0742	ribosomal rna small subunit methyltransferase
C7H83_RS08630	COG4471	UPF0298 protein
C7H83_RS08635	COG3679	Belongs to the UPF0342 family
C7H83_RS08645	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7H83_RS08650	COG0772	Belongs to the SEDS family
C7H83_RS08655	COG4838	Belongs to the UPF0358 family
C7H83_RS08660	COG1217	gtp-binding protein TYPA
C7H83_RS08665	COG0483	inositol monophosphate 1-phosphatase activity
C7H83_RS08670	COG4476	Belongs to the UPF0223 family
C7H83_RS08705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7H83_RS08710	COG0516	GMP reductase activity
C7H83_RS08715	COG4989	oxidoreductase activity
C7H83_RS08720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7H83_RS08725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7H83_RS08730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7H83_RS08735	COG1966	Carbon starvation protein
C7H83_RS08740	COG3279	Response regulator of the LytR AlgR family
C7H83_RS08745	COG3275	phosphorelay sensor kinase activity
C7H83_RS08760	COG1876	peptidase activity
C7H83_RS08790	COG0436	Aminotransferase
C7H83_RS08810	COG1227	inorganic diphosphatase activity
C7H83_RS08815	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7H83_RS08825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7H83_RS08830	COG0187	DNA topoisomerase II activity
C7H83_RS08835	COG1832	CoA-binding protein
C7H83_RS08840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7H83_RS08855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7H83_RS08860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7H83_RS08870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7H83_RS08875	COG0758	DNA mediated transformation
C7H83_RS08880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7H83_RS08885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7H83_RS08925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7H83_RS08930	COG0681	Belongs to the peptidase S26 family
C7H83_RS08935	COG3409	Peptidoglycan-binding domain 1 protein
C7H83_RS08935	COG0793	Belongs to the peptidase S41A family
C7H83_RS08940	COG4479	Belongs to the UPF0346 family
C7H83_RS08950	COG4698	Protein conserved in bacteria
C7H83_RS08955	COG2755	lipolytic protein G-D-S-L family
C7H83_RS08960	COG1307	EDD domain protein, DegV family
C7H83_RS08965	COG0371	Dehydrogenase
C7H83_RS08970	COG1272	protein, Hemolysin III
C7H83_RS08985	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7H83_RS08990	COG0488	(ABC) transporter
C7H83_RS08995	COG0768	penicillin binding
C7H83_RS09000	COG1316	TRANSCRIPTIONal
C7H83_RS09005	COG1682	transport, permease protein
C7H83_RS09010	COG1134	teichoic acid transport
C7H83_RS09015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7H83_RS09030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7H83_RS09035	COG2246	polysaccharide biosynthetic process
C7H83_RS09040	COG2246	polysaccharide biosynthetic process
C7H83_RS09045	COG3385	transposase activity
C7H83_RS09055	COG5521	maltodextrose utilization protein MalA
C7H83_RS09065	COG0463	Glycosyl transferase, family 2
C7H83_RS09085	COG4841	protein insertion into membrane
C7H83_RS09090	COG0569	domain protein
C7H83_RS09095	COG2197	response regulator
C7H83_RS09100	COG4585	Histidine kinase
C7H83_RS09110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7H83_RS09115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7H83_RS09120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7H83_RS09125	COG0438	transferase activity, transferring glycosyl groups
C7H83_RS09150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7H83_RS09165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7H83_RS09195	COG0436	Aminotransferase
C7H83_RS09205	COG1199	ATP-dependent helicase activity
C7H83_RS09205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7H83_RS09210	COG1278	Cold shock
C7H83_RS09220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7H83_RS09225	COG2217	Heavy metal translocating P-type atpase
C7H83_RS09245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7H83_RS09265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7H83_RS09285	COG2217	Heavy metal translocating P-type atpase
C7H83_RS09290	COG0640	Transcriptional regulator
C7H83_RS09320	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7H83_RS09330	COG1396	sequence-specific DNA binding
C7H83_RS09380	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7H83_RS09385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS09390	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7H83_RS09390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7H83_RS09395	COG0513	Belongs to the DEAD box helicase family
C7H83_RS09400	COG0673	inositol 2-dehydrogenase activity
C7H83_RS09410	COG1686	Belongs to the peptidase S11 family
C7H83_RS09430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7H83_RS09440	COG1254	Belongs to the acylphosphatase family
C7H83_RS09455	COG0751	glycine-tRNA ligase activity
C7H83_RS09460	COG0752	glycyl-tRNA synthetase alpha subunit
C7H83_RS09465	COG1381	Involved in DNA repair and RecF pathway recombination
C7H83_RS09470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7H83_RS09475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7H83_RS09480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7H83_RS09490	COG1702	phosphate starvation-inducible protein PhoH
C7H83_RS09495	COG1610	YqeY-like protein
C7H83_RS09500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7H83_RS09510	COG4536	flavin adenine dinucleotide binding
C7H83_RS09515	COG0735	belongs to the Fur family
C7H83_RS09520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7H83_RS09525	COG0083	homoserine kinase activity
C7H83_RS09535	COG0640	Transcriptional regulator
C7H83_RS09540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7H83_RS09545	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS09550	COG0561	phosphatase activity
C7H83_RS09570	COG3763	UPF0154 protein
C7H83_RS09575	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS09580	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7H83_RS09590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7H83_RS09595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7H83_RS09595	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7H83_RS09615	COG0436	Aminotransferase
C7H83_RS09620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7H83_RS09630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7H83_RS09635	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS09640	COG1609	Transcriptional regulator
C7H83_RS09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7H83_RS09670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7H83_RS09675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_RS09680	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7H83_RS09705	COG0745	RESPONSE REGULATOR receiver
C7H83_RS09710	COG5002	protein histidine kinase activity
C7H83_RS09715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_RS09720	COG1950	PFAM Membrane protein of
C7H83_RS09735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_RS09740	COG1950	PFAM Membrane protein of
C7H83_RS09755	COG0704	Plays a role in the regulation of phosphate uptake
C7H83_RS09760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7H83_RS09765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7H83_RS09770	COG0581	inorganic phosphate transmembrane transporter activity
C7H83_RS09775	COG0573	inorganic phosphate transmembrane transporter activity
C7H83_RS09780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7H83_RS09790	COG2177	Part of the ABC transporter FtsEX involved in
C7H83_RS09795	COG2884	Cell division ATP-binding protein ftsE
C7H83_RS09805	COG0653	protein targeting
C7H83_RS09820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7H83_RS09830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS09840	COG1739	Uncharacterized protein family UPF0029
C7H83_RS09845	COG2188	Transcriptional regulator
C7H83_RS09865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7H83_RS09875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7H83_RS09885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7H83_RS09890	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7H83_RS09895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7H83_RS09900	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7H83_RS09905	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_RS09910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7H83_RS09915	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7H83_RS09920	COG0356	it plays a direct role in the translocation of protons across the membrane
C7H83_RS09925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7H83_RS09930	COG0557	exoribonuclease II activity
C7H83_RS09940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7H83_RS09945	COG0148	phosphopyruvate hydratase activity
C7H83_RS09950	COG0149	triose-phosphate isomerase activity
C7H83_RS09955	COG0126	phosphoglycerate kinase activity
C7H83_RS09970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7H83_RS10215	COG0556	nucleotide-excision repair
C7H83_RS10285	COG0095	Lipoate-protein ligase
C7H83_RS10290	COG1078	dGTPase activity
C7H83_RS10295	COG2816	NAD+ diphosphatase activity
C7H83_RS10300	COG0346	lactoylglutathione lyase activity
C7H83_RS10310	COG3118	belongs to the thioredoxin family
C7H83_RS10315	COG1193	negative regulation of DNA recombination
C7H83_RS10330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7H83_RS10340	COG2059	Chromate
C7H83_RS10365	COG4175	Glycine betaine
C7H83_RS10365	COG3448	diguanylate cyclase activity
C7H83_RS10370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7H83_RS10375	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS10385	COG3906	Belongs to the UPF0473 family
C7H83_RS10390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7H83_RS10395	COG4472	Bacterial protein of unknown function (DUF965)
C7H83_RS10400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7H83_RS10405	COG0488	(ABC) transporter
C7H83_RS10410	COG0686	Belongs to the AlaDH PNT family
C7H83_RS10430	COG0604	alcohol dehydrogenase
C7H83_RS10440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7H83_RS10445	COG4684	Psort location CytoplasmicMembrane, score
C7H83_RS10465	COG0800	Aldolase
C7H83_RS10470	COG4948	Mandelate Racemase Muconate Lactonizing
C7H83_RS10475	COG3711	transcriptional antiterminator
C7H83_RS10475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS10485	COG3414	Phosphotransferase system galactitol-specific IIB component
C7H83_RS10550	COG0765	amino acid transport
C7H83_RS10555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_RS10560	COG1373	ATPase (AAA superfamily
C7H83_RS10605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_RS10610	COG2855	membrane
C7H83_RS10615	COG0583	DNA-binding transcription factor activity
C7H83_RS10620	COG2084	Dehydrogenase
C7H83_RS10625	COG1668	transmembrane transport
C7H83_RS10630	COG4152	abc transporter atp-binding protein
C7H83_RS10650	COG1607	acyl-coa hydrolase
C7H83_RS10655	COG0825	malonyl-CoA metabolic process
C7H83_RS10660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7H83_RS10665	COG0439	Biotin carboxylase
C7H83_RS10670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7H83_RS10675	COG0511	ligase activity, forming carbon-carbon bonds
C7H83_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
C7H83_RS10690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7H83_RS10695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7H83_RS10700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7H83_RS10705	COG1846	Transcriptional regulator
C7H83_RS10715	COG1428	Deoxynucleoside kinase
C7H83_RS10720	COG4703	Protein of unknown function (DUF1797)
C7H83_RS10725	COG2084	Dehydrogenase
C7H83_RS10730	COG0438	transferase activity, transferring glycosyl groups
C7H83_RS10745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7H83_RS10750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS10760	COG0542	response to heat
C7H83_RS10770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7H83_RS10775	COG1253	flavin adenine dinucleotide binding
C7H83_RS10785	COG3557	Belongs to the UPF0374 family
C7H83_RS10795	COG2137	regulation of response to DNA damage stimulus
C7H83_RS10805	COG0442	prolyl-tRNA aminoacylation
C7H83_RS10810	COG0750	zinc metalloprotease
C7H83_RS10815	COG4589	Belongs to the CDS family
C7H83_RS10820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7H83_RS10825	COG0233	cytoplasmic translational termination
C7H83_RS10830	COG0528	UMP kinase activity
C7H83_RS10835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7H83_RS10840	COG0052	Belongs to the universal ribosomal protein uS2 family
C7H83_RS10845	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7H83_RS10860	COG1214	PFAM Peptidase M22, glycoprotease
C7H83_RS10890	COG1609	Transcriptional regulator
C7H83_RS10900	COG1609	Transcriptional regulator
C7H83_RS10905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7H83_RS10910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7H83_RS10915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7H83_RS10920	COG2207	Transcriptional regulator
C7H83_RS10930	COG2814	Major facilitator Superfamily
C7H83_RS10940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7H83_RS10945	COG1940	carbohydrate kinase activity
C7H83_RS10960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7H83_RS10965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7H83_RS10985	COG0617	tRNA 3'-terminal CCA addition
C7H83_RS10990	COG1694	Mazg nucleotide pyrophosphohydrolase
C7H83_RS10995	COG5582	Belongs to the UPF0302 family
C7H83_RS11010	COG0776	regulation of translation
C7H83_RS11015	COG1160	GTP binding
C7H83_RS11020	COG0539	negative regulation of cytoplasmic translation
C7H83_RS11030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7H83_RS11040	COG0514	ATP-dependent DNA helicase (RecQ)
C7H83_RS11050	COG1141	Ferredoxin
C7H83_RS11055	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7H83_RS11060	COG1187	pseudouridine synthase activity
C7H83_RS11065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7H83_RS11070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7H83_RS11075	COG4974	Belongs to the 'phage' integrase family
C7H83_RS11080	COG0735	belongs to the Fur family
C7H83_RS11085	COG2996	Protein conserved in bacteria
C7H83_RS11100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7H83_RS11105	COG0358	DNA primase activity
C7H83_RS11115	COG0741	lytic transglycosylase activity
C7H83_RS11135	COG3425	synthase
C7H83_RS11145	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS11150	COG1464	Belongs to the NlpA lipoprotein family
C7H83_RS11165	COG1882	Formate acetyltransferase
C7H83_RS11170	COG1349	DNA-binding transcription factor activity
C7H83_RS11175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7H83_RS11190	COG2190	(PTS) system
C7H83_RS11200	COG0582	viral genome integration into host DNA
C7H83_RS11210	COG2207	Transcriptional regulator
C7H83_RS11235	COG3385	transposase activity
C7H83_RS11255	COG1131	(ABC) transporter
C7H83_RS11305	COG4585	Histidine kinase
C7H83_RS11355	COG0582	viral genome integration into host DNA
C7H83_RS11435	COG5002	protein histidine kinase activity
C7H83_RS11440	COG0745	RESPONSE REGULATOR receiver
C7H83_RS11445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7H83_RS11475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7H83_RS11480	COG1399	metal-binding, possibly nucleic acid-binding protein
C7H83_RS11490	COG0205	6-phosphofructokinase activity
C7H83_RS11495	COG0587	DNA-directed DNA polymerase activity
C7H83_RS11505	COG2252	PERMEase
C7H83_RS11510	COG0561	phosphatase activity
C7H83_RS11520	COG3385	transposase activity
C7H83_RS11545	COG0166	Belongs to the GPI family
C7H83_RS11550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7H83_RS11555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7H83_RS11565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7H83_RS11570	COG1368	sulfuric ester hydrolase activity
C7H83_RS11585	COG5002	protein histidine kinase activity
C7H83_RS11585	COG3850	Histidine kinase
C7H83_RS11590	COG0745	RESPONSE REGULATOR receiver
C7H83_RS11610	COG1956	GAF domain-containing protein
C7H83_RS11615	COG2848	UPF0210 protein
C7H83_RS11620	COG3830	Belongs to the UPF0237 family
C7H83_RS11630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7H83_RS11635	COG0336	Belongs to the RNA methyltransferase TrmD family
C7H83_RS11665	COG3052	prosthetic group binding
C7H83_RS11670	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C7H83_RS11680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7H83_RS11715	COG0511	ligase activity, forming carbon-carbon bonds
C7H83_RS11720	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7H83_RS11730	COG1837	Belongs to the UPF0109 family
C7H83_RS11735	COG0228	four-way junction DNA binding
C7H83_RS11740	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7H83_RS11755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7H83_RS11760	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7H83_RS11765	COG0436	Aminotransferase
C7H83_RS11775	COG2608	mercury ion transmembrane transporter activity
C7H83_RS11780	COG3682	Transcriptional regulator
C7H83_RS11785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7H83_RS11790	COG1295	ribonuclease BN
C7H83_RS11795	COG0024	Methionine aminopeptidase
C7H83_RS11800	COG0716	FMN binding
C7H83_RS11805	COG1309	transcriptional regulator
C7H83_RS11810	COG2309	aminopeptidase activity
C7H83_RS11820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7H83_RS11825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7H83_RS11840	COG3599	regulation of cell shape
C7H83_RS11845	COG2302	S4 RNA-binding domain
C7H83_RS11850	COG0762	integral membrane protein
C7H83_RS11855	COG1799	cell septum assembly
C7H83_RS11860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7H83_RS11885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7H83_RS11895	COG0768	penicillin binding
C7H83_RS11910	COG2001	Belongs to the MraZ family
C7H83_RS11930	COG0497	DNA recombination
C7H83_RS11935	COG1438	arginine binding
C7H83_RS11940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7H83_RS11950	COG1722	exodeoxyribonuclease VII activity
C7H83_RS11955	COG1570	exodeoxyribonuclease VII activity
C7H83_RS11960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7H83_RS11965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7H83_RS11970	COG1302	Protein conserved in bacteria
C7H83_RS11975	COG0006	proline dipeptidase activity
C7H83_RS11985	COG4864	UPF0365 protein
C7H83_RS12005	COG3716	PTS system mannose fructose sorbose family IID component
C7H83_RS12010	COG3715	PTS system
C7H83_RS12020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7H83_RS12020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS12025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7H83_RS12025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7H83_RS12035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7H83_RS12045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7H83_RS12055	COG4122	O-methyltransferase activity
C7H83_RS12100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7H83_RS12105	COG0563	adenylate kinase activity
C7H83_RS12115	COG2217	Heavy metal translocating P-type atpase
C7H83_RS12125	COG2217	Heavy metal translocating P-type atpase
C7H83_RS12135	COG3682	Transcriptional regulator
C7H83_RS12140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7H83_RS12145	COG0656	L-ascorbic acid biosynthetic process
C7H83_RS12150	COG0095	Lipoate-protein ligase
C7H83_RS12160	COG0602	queuosine metabolic process
C7H83_RS12180	COG4467	Involved in initiation control of chromosome replication
C7H83_RS12190	COG0470	DNA polymerase III
C7H83_RS12195	COG3870	Protein conserved in bacteria
C7H83_RS12200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7H83_RS12205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7H83_RS12210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7H83_RS12215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7H83_RS12220	COG2723	6-phospho-beta-galactosidase activity
C7H83_RS12225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7H83_RS12230	COG2910	NAD(P)H-binding
C7H83_RS12235	COG0222	ribosome binding
C7H83_RS12240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7H83_RS12245	COG0081	regulation of translation
C7H83_RS12260	COG0250	Participates in transcription elongation, termination and antitermination
C7H83_RS12265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7H83_RS12270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7H83_RS12280	COG1597	lipid kinase activity
C7H83_RS12290	COG4708	membrane
C7H83_RS12300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7H83_RS12310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7H83_RS12315	COG0500	methyltransferase
C7H83_RS12320	COG3142	Participates in the control of copper homeostasis
C7H83_RS12325	COG2239	Acts as a magnesium transporter
C7H83_RS12330	COG0564	pseudouridine synthase activity
C7H83_RS12335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7H83_RS12340	COG2357	RelA SpoT domain protein
C7H83_RS12345	COG4116	CYTH
C7H83_RS12360	COG4862	establishment of competence for transformation
C7H83_RS12365	COG1393	Belongs to the ArsC family
C7H83_RS12370	COG1132	(ABC) transporter
C7H83_RS12375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7H83_RS12380	COG0419	ATPase involved in DNA repair
C7H83_RS12385	COG0420	3'-5' exonuclease activity
C7H83_RS12390	COG0204	Acyl-transferase
C7H83_RS12395	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7H83_RS12400	COG2827	Endonuclease containing a URI domain
C7H83_RS12410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7H83_RS12425	COG1131	(ABC) transporter
C7H83_RS12435	COG4658	electron transport chain
C7H83_RS12440	COG4656	Part of a membrane complex involved in electron transport
C7H83_RS12445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7H83_RS12455	COG0095	Lipoate-protein ligase
C7H83_RS12465	COG0647	UMP catabolic process
C7H83_RS12470	COG4470	Protein conserved in bacteria
C7H83_RS12475	COG0737	Belongs to the 5'-nucleotidase family
C7H83_RS12490	COG0590	tRNA wobble adenosine to inosine editing
C7H83_RS12500	COG2738	Putative neutral zinc metallopeptidase
C7H83_RS12505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7H83_RS12510	COG0019	diaminopimelate decarboxylase activity
C7H83_RS12515	COG1473	amidohydrolase
C7H83_RS12520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7H83_RS12525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7H83_RS12530	COG2171	N-acyltransferase activity
C7H83_RS12535	COG0028	Belongs to the TPP enzyme family
C7H83_RS12550	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7H83_RS12550	COG0493	'glutamate synthase
C7H83_RS12555	COG0543	2 iron, 2 sulfur cluster binding
C7H83_RS12560	COG0716	FMN binding
C7H83_RS12570	COG0402	S-adenosylhomocysteine deaminase activity
C7H83_RS12580	COG3608	succinylglutamate desuccinylase aspartoacylase
C7H83_RS12580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7H83_RS12610	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7H83_RS12610	COG3608	succinylglutamate desuccinylase aspartoacylase
C7H83_RS12620	COG0719	Fe-S assembly protein
C7H83_RS12630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7H83_RS12640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS12645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_RS12645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7H83_RS12645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS12655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7H83_RS12655	COG3711	transcriptional antiterminator
C7H83_RS12675	COG1215	transferase activity, transferring glycosyl groups
C7H83_RS12695	COG1045	serine acetyltransferase
C7H83_RS12700	COG0626	cystathionine gamma-synthase activity
C7H83_RS12705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7H83_RS12710	COG0693	protein deglycase activity
C7H83_RS12715	COG3527	Alpha-acetolactate decarboxylase
C7H83_RS12720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7H83_RS12740	COG2226	methyltransferase
C7H83_RS12750	COG1125	glycine betaine transport
C7H83_RS12750	COG0517	IMP dehydrogenase activity
C7H83_RS12755	COG1174	glycine betaine transport
C7H83_RS12760	COG1132	(ABC) transporter
C7H83_RS12770	COG3104	oligopeptide transport
C7H83_RS12780	COG1428	Deoxynucleoside kinase
C7H83_RS12790	COG1053	succinate dehydrogenase
C7H83_RS12790	COG3976	FMN-binding domain protein
C7H83_RS12790	COG0431	NADPH-dependent FMN reductase
C7H83_RS12795	COG1070	Carbohydrate kinase
C7H83_RS12815	COG0114	fumarate hydratase activity
C7H83_RS12835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7H83_RS12845	COG1132	(ABC) transporter
C7H83_RS12850	COG1132	(ABC) transporter
C7H83_RS12865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7H83_RS12870	COG0719	Fe-S assembly protein
C7H83_RS12890	COG1185	polyribonucleotide nucleotidyltransferase activity
C7H83_RS12895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7H83_RS12905	COG0628	permease
C7H83_RS12915	COG2706	6-phosphogluconolactonase activity
C7H83_RS12920	COG0488	(ABC) transporter
C7H83_RS12930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_RS12935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_RS12935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7H83_RS12945	COG2239	Acts as a magnesium transporter
C7H83_RS12950	COG0675	Transposase, IS605 OrfB family
C7H83_RS12955	COG4608	Belongs to the ABC transporter superfamily
C7H83_RS12960	COG0444	Belongs to the ABC transporter superfamily
C7H83_RS12965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7H83_RS12970	COG0601	transmembrane transport
C7H83_RS12980	COG4166	transmembrane transport
C7H83_RS12985	COG4166	transmembrane transport
C7H83_RS12990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7H83_RS12995	COG1674	ftsk spoiiie
C7H83_RS12995	COG1280	lysine exporter protein (LysE YggA)
C7H83_RS13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7H83_RS13010	COG1126	abc transporter atp-binding protein
C7H83_RS13015	COG0765	amino acid transport
C7H83_RS13035	COG3842	ATPase activity
C7H83_RS13060	COG0482	sulfurtransferase activity
C7H83_RS13070	COG1104	cysteine desulfurase activity
C7H83_RS13075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7H83_RS13085	COG3590	peptidase
C7H83_RS13090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7H83_RS13110	COG3853	Toxic anion resistance protein (TelA)
C7H83_RS13115	COG0531	amino acid
C7H83_RS13125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7H83_RS13145	COG1490	D-aminoacyl-tRNA deacylase activity
C7H83_RS13150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7H83_RS13155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7H83_RS13160	COG2264	protein methyltransferase activity
C7H83_RS13165	COG2094	Belongs to the DNA glycosylase MPG family
C7H83_RS13170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7H83_RS13205	COG3385	transposase activity
C7H83_RS13235	COG1131	(ABC) transporter
C7H83_RS13240	COG1131	(ABC) transporter
C7H83_RS13250	COG0783	Belongs to the Dps family
C7H83_RS13255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7H83_RS13285	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7H83_RS13290	COG3576	pyridoxamine 5-phosphate
C7H83_RS13300	COG1652	LysM domain
C7H83_RS13300	COG2823	Periplasmic or secreted lipoprotein
C7H83_RS13335	COG0783	Belongs to the Dps family