locus-tag	class	description
CFI11_RS00005	COG0424	maF-like protein
CFI11_RS00010	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFI11_RS00015	COG0237	dephospho-CoA kinase activity
CFI11_RS00020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFI11_RS00025	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFI11_RS00030	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFI11_RS00060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFI11_RS00065	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFI11_RS00080	COG1074	ATP-dependent DNA helicase activity
CFI11_RS00090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFI11_RS00095	COG3178	'Phosphotransferase
CFI11_RS00115	COG1999	signal sequence binding
CFI11_RS00120	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFI11_RS00130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFI11_RS00145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFI11_RS00175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFI11_RS00180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFI11_RS00210	COG0028	Belongs to the TPP enzyme family
CFI11_RS00210	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CFI11_RS00255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFI11_RS00270	COG1122	ATPase activity
CFI11_RS00275	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFI11_RS00280	COG1268	BioY protein
CFI11_RS00285	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS00295	COG2814	Major facilitator Superfamily
CFI11_RS00300	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS00305	COG0300	oxidoreductase activity
CFI11_RS00365	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS00385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_RS00390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_RS00395	COG1136	(ABC) transporter
CFI11_RS00415	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS00420	COG2091	lysine biosynthetic process via aminoadipic acid
CFI11_RS00425	COG2207	Transcriptional regulator
CFI11_RS00425	COG3708	Transcriptional regulator
CFI11_RS00430	COG1706	bacterial-type flagellum-dependent cell motility
CFI11_RS00450	COG1360	Flagellar Motor Protein
CFI11_RS00455	COG1338	Plays a role in the flagellum-specific transport system
CFI11_RS00460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFI11_RS00470	COG1766	The M ring may be actively involved in energy transduction
CFI11_RS00490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFI11_RS00505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFI11_RS00515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFI11_RS00530	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFI11_RS00540	COG4786	Flagellar basal body rod
CFI11_RS00545	COG4786	Flagellar basal body rod
CFI11_RS00550	COG1987	bacterial-type flagellum assembly
CFI11_RS00555	COG1677	Flagellar hook-basal body complex protein FliE
CFI11_RS00560	COG1558	bacterial-type flagellum-dependent cell motility
CFI11_RS00565	COG1815	bacterial-type flagellum-dependent cell motility
CFI11_RS00580	COG5443	negative regulation of bacterial-type flagellum assembly
CFI11_RS00590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFI11_RS00615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS00620	COG1177	transmembrane transport
CFI11_RS00625	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_RS00630	COG3842	ATPase activity
CFI11_RS00640	COG1802	Transcriptional regulator
CFI11_RS00650	COG3842	ATPase activity
CFI11_RS00660	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_RS00665	COG1177	transmembrane transport
CFI11_RS00675	COG2951	lytic endotransglycosylase activity
CFI11_RS00680	COG2378	regulation of single-species biofilm formation
CFI11_RS00700	COG2072	flavoprotein involved in K transport
CFI11_RS00730	COG1846	Transcriptional regulator
CFI11_RS00735	COG0745	RESPONSE REGULATOR receiver
CFI11_RS00740	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFI11_RS00745	COG1722	exodeoxyribonuclease VII activity
CFI11_RS00750	COG0142	geranyltranstransferase activity
CFI11_RS00755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFI11_RS00775	COG3396	Phenylacetate-CoA oxygenase
CFI11_RS00780	COG3460	Phenylacetate-CoA oxygenase
CFI11_RS00785	COG3396	Phenylacetate-CoA oxygenase
CFI11_RS00790	COG2151	metal-sulfur cluster biosynthetic enzyme
CFI11_RS00800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFI11_RS00820	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS00825	COG0235	Class ii aldolase
CFI11_RS00825	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CFI11_RS00845	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFI11_RS00850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFI11_RS00890	COG1132	(ABC) transporter
CFI11_RS00900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_RS00905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_RS00920	COG0697	spore germination
CFI11_RS00940	COG0560	Phosphoserine phosphatase
CFI11_RS00945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFI11_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFI11_RS00955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFI11_RS00960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFI11_RS00965	COG1063	alcohol dehydrogenase
CFI11_RS00970	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_RS00975	COG1396	sequence-specific DNA binding
CFI11_RS00980	COG0183	Belongs to the thiolase family
CFI11_RS00990	COG2226	methyltransferase
CFI11_RS00995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFI11_RS01000	COG1024	Enoyl-CoA hydratase
CFI11_RS01005	COG0268	Binds directly to 16S ribosomal RNA
CFI11_RS01010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFI11_RS01020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFI11_RS01050	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFI11_RS01065	COG1054	Belongs to the UPF0176 family
CFI11_RS01075	COG1335	isochorismatase
CFI11_RS01085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFI11_RS01095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFI11_RS01105	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFI11_RS01125	COG0514	ATP-dependent DNA helicase (RecQ)
CFI11_RS01130	COG3022	response to hydroperoxide
CFI11_RS01135	COG5002	protein histidine kinase activity
CFI11_RS01135	COG2205	protein histidine kinase activity
CFI11_RS01135	COG0784	Response regulator, receiver
CFI11_RS01140	COG2373	Large extracellular alpha-helical protein
CFI11_RS01145	COG4953	penicillin-binding protein 1C
CFI11_RS01175	COG0714	Associated with various cellular activities
CFI11_RS01205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFI11_RS01205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFI11_RS01235	COG1131	(ABC) transporter
CFI11_RS01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFI11_RS01255	COG0793	Belongs to the peptidase S41A family
CFI11_RS01265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS01275	COG0800	Aldolase
CFI11_RS01280	COG0129	dihydroxy-acid dehydratase activity
CFI11_RS01300	COG0129	dihydroxy-acid dehydratase activity
CFI11_RS01305	COG2274	protein secretion by the type I secretion system
CFI11_RS01310	COG1266	CAAX protease self-immunity
CFI11_RS01315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFI11_RS01320	COG0285	dihydrofolate synthase activity
CFI11_RS01325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFI11_RS01335	COG2423	ornithine cyclodeaminase activity
CFI11_RS01345	COG1671	Belongs to the UPF0178 family
CFI11_RS01350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFI11_RS01355	COG0679	Auxin Efflux Carrier
CFI11_RS01375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFI11_RS01380	COG2814	Major facilitator Superfamily
CFI11_RS01400	COG2610	gluconate transmembrane transporter activity
CFI11_RS01415	COG0183	Belongs to the thiolase family
CFI11_RS01420	COG2050	protein possibly involved in aromatic compounds catabolism
CFI11_RS01425	COG2030	dehydratase
CFI11_RS01425	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_RS01430	COG3327	negative regulation of DNA-templated transcription, initiation
CFI11_RS01435	COG2172	sigma factor antagonist activity
CFI11_RS01465	COG0583	DNA-binding transcription factor activity
CFI11_RS01480	COG0583	DNA-binding transcription factor activity
CFI11_RS01485	COG0456	acetyltransferase
CFI11_RS01495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_RS01505	COG1917	Cupin 2, conserved barrel domain protein
CFI11_RS01510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFI11_RS01515	COG0527	aspartate kinase activity
CFI11_RS01520	COG3473	Maleate cis-trans isomerase
CFI11_RS01550	COG0791	NLP P60 protein
CFI11_RS01555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFI11_RS01565	COG0288	reversible hydration of carbon dioxide
CFI11_RS01590	COG3971	2-oxopent-4-enoate hydratase activity
CFI11_RS01625	COG2308	Evidence 4 Homologs of previously reported genes of
CFI11_RS01635	COG1305	Transglutaminase-like
CFI11_RS01650	COG0254	rRNA binding
CFI11_RS01655	COG0335	large ribosomal subunit rRNA binding
CFI11_RS01660	COG0336	Belongs to the RNA methyltransferase TrmD family
CFI11_RS01665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFI11_RS01670	COG0778	Nitroreductase
CFI11_RS01675	COG0228	four-way junction DNA binding
CFI11_RS01710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFI11_RS01765	COG1802	Transcriptional regulator
CFI11_RS01770	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFI11_RS01780	COG3237	CsbD-like
CFI11_RS01795	COG0784	Response regulator, receiver
CFI11_RS01810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_RS01815	COG1295	ribonuclease BN
CFI11_RS01825	COG0400	carboxylic ester hydrolase activity
CFI11_RS01830	COG0346	lactoylglutathione lyase activity
CFI11_RS01840	COG2116	formate transmembrane transporter activity
CFI11_RS01855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFI11_RS01885	COG0583	DNA-binding transcription factor activity
CFI11_RS01895	COG0356	it plays a direct role in the translocation of protons across the membrane
CFI11_RS01900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFI11_RS01905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFI11_RS01910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFI11_RS01915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFI11_RS01945	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CFI11_RS01960	COG0435	Glutathione S-transferase
CFI11_RS01975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CFI11_RS01980	COG0242	peptide deformylase activity
CFI11_RS01985	COG0242	peptide deformylase activity
CFI11_RS01990	COG0242	peptide deformylase activity
CFI11_RS01995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFI11_RS02005	COG0328	RNA-DNA hybrid ribonuclease activity
CFI11_RS02010	COG4106	trans-aconitate 2-methyltransferase activity
CFI11_RS02030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFI11_RS02040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFI11_RS02045	COG1758	RNA polymerase activity
CFI11_RS02060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFI11_RS02065	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS02075	COG0736	holo-[acyl-carrier-protein] synthase activity
CFI11_RS02080	COG0681	Belongs to the peptidase S26 family
CFI11_RS02085	COG0571	ribonuclease III activity
CFI11_RS02090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFI11_RS02100	COG1381	Involved in DNA repair and RecF pathway recombination
CFI11_RS02130	COG1648	precorrin-2 dehydrogenase activity
CFI11_RS02130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_RS02135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFI11_RS02140	COG0243	molybdopterin cofactor binding
CFI11_RS02145	COG2146	nitrite reductase [NAD(P)H] activity
CFI11_RS02150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFI11_RS02155	COG1116	anion transmembrane transporter activity
CFI11_RS02160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS02165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_RS02175	COG1116	anion transmembrane transporter activity
CFI11_RS02175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_RS02180	COG3707	response regulator
CFI11_RS02185	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFI11_RS02190	COG0745	RESPONSE REGULATOR receiver
CFI11_RS02195	COG2205	protein histidine kinase activity
CFI11_RS02200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFI11_RS02205	COG1660	Displays ATPase and GTPase activities
CFI11_RS02215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFI11_RS02225	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_RS02255	COG0300	oxidoreductase activity
CFI11_RS02265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFI11_RS02270	COG2124	cytochrome p450
CFI11_RS02280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFI11_RS02295	COG0110	maltose O-acetyltransferase activity
CFI11_RS02300	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFI11_RS02305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_RS02400	COG4974	Belongs to the 'phage' integrase family
CFI11_RS02465	COG0250	Participates in transcription elongation, termination and antitermination
CFI11_RS02470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFI11_RS02475	COG0081	regulation of translation
CFI11_RS02480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFI11_RS02485	COG0222	ribosome binding
CFI11_RS02490	COG0085	RNA polymerase activity
CFI11_RS02495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFI11_RS02500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS02510	COG3842	ATPase activity
CFI11_RS02515	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS02555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFI11_RS02560	COG0049	tRNA binding
CFI11_RS02565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFI11_RS02575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFI11_RS02580	COG0051	transcription antitermination factor activity, RNA binding
CFI11_RS02585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFI11_RS02590	COG0088	Forms part of the polypeptide exit tunnel
CFI11_RS02595	COG0089	rRNA binding
CFI11_RS02605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFI11_RS02610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFI11_RS02615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFI11_RS02620	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFI11_RS02625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFI11_RS02635	COG0255	Belongs to the universal ribosomal protein uL29 family
CFI11_RS02640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFI11_RS02645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFI11_RS02650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFI11_RS02655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFI11_RS02660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFI11_RS02665	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFI11_RS02670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFI11_RS02675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFI11_RS02680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFI11_RS02685	COG1841	ribosomal large subunit assembly
CFI11_RS02705	COG0200	Binds to the 23S rRNA
CFI11_RS02710	COG0201	protein transport
CFI11_RS02715	COG0563	adenylate kinase activity
CFI11_RS02720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFI11_RS02725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFI11_RS02730	COG0202	RNA polymerase activity
CFI11_RS02735	COG0203	ribosomal protein L17
CFI11_RS02740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFI11_RS02745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFI11_RS02750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFI11_RS02755	COG0564	pseudouridine synthase activity
CFI11_RS02760	COG0546	phosphoglycolate phosphatase activity
CFI11_RS02770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFI11_RS02775	COG4597	amino acid ABC transporter
CFI11_RS02780	COG0765	amino acid transport
CFI11_RS02785	COG1126	abc transporter atp-binding protein
CFI11_RS02805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFI11_RS02810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFI11_RS02820	COG0706	membrane insertase activity
CFI11_RS02825	COG2200	EAL domain
CFI11_RS02830	COG0037	tRNA processing
CFI11_RS02845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFI11_RS02850	COG0594	ribonuclease P activity
CFI11_RS02855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFI11_RS02865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFI11_RS02870	COG3852	Histidine kinase
CFI11_RS02885	COG0235	Class ii aldolase
CFI11_RS02890	COG3395	kinase activity
CFI11_RS02900	COG0473	3-isopropylmalate dehydrogenase activity
CFI11_RS02920	COG1802	Transcriptional regulator
CFI11_RS02970	COG0577	efflux transmembrane transporter activity
CFI11_RS02970	COG1136	(ABC) transporter
CFI11_RS03000	COG1175	transmembrane transport
CFI11_RS03005	COG0395	ABC-type sugar transport system, permease component
CFI11_RS03055	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFI11_RS03125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CFI11_RS03130	COG1177	transmembrane transport
CFI11_RS03140	COG3842	ATPase activity
CFI11_RS03155	COG0583	DNA-binding transcription factor activity
CFI11_RS03165	COG0251	oxidation-reduction process
CFI11_RS03170	COG2072	flavoprotein involved in K transport
CFI11_RS03180	COG0583	DNA-binding transcription factor activity
CFI11_RS03185	COG0450	alkyl hydroperoxide reductase
CFI11_RS03200	COG2391	methyltransferase activity
CFI11_RS03230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS03250	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS03275	COG1477	protein flavinylation
CFI11_RS03280	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CFI11_RS03285	COG1805	sodium ion transport
CFI11_RS03295	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CFI11_RS03315	COG2084	Dehydrogenase
CFI11_RS03320	COG3386	PFAM SMP-30 Gluconolaconase
CFI11_RS03325	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS03330	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS03335	COG1129	ABC transporter
CFI11_RS03345	COG1609	Transcriptional regulator
CFI11_RS03370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFI11_RS03375	COG0772	Belongs to the SEDS family
CFI11_RS03380	COG0768	penicillin binding
CFI11_RS03425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS03445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_RS03460	COG1959	2 iron, 2 sulfur cluster binding
CFI11_RS03470	COG4181	ATPase activity
CFI11_RS03485	COG1278	Cold shock
CFI11_RS03500	COG1376	ErfK ybiS ycfS ynhG family protein
CFI11_RS03520	COG0488	(ABC) transporter
CFI11_RS03525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFI11_RS03540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CFI11_RS03565	COG1192	Involved in chromosome partitioning
CFI11_RS03585	COG0589	response to stress
CFI11_RS03595	COG0556	nucleotide-excision repair
CFI11_RS03605	COG0454	-acetyltransferase
CFI11_RS03620	COG1522	sequence-specific DNA binding
CFI11_RS03635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS03640	COG0747	negative chemotaxis
CFI11_RS03645	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_RS03650	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS03655	COG4608	Belongs to the ABC transporter superfamily
CFI11_RS03660	COG0028	Belongs to the TPP enzyme family
CFI11_RS03665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFI11_RS03675	COG0765	amino acid transport
CFI11_RS03680	COG0765	amino acid transport
CFI11_RS03690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFI11_RS03695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFI11_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS03740	COG2010	Cytochrome c
CFI11_RS03745	COG0583	DNA-binding transcription factor activity
CFI11_RS03750	COG0348	domain, Protein
CFI11_RS03770	COG1686	Belongs to the peptidase S11 family
CFI11_RS03785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFI11_RS03800	COG0408	coproporphyrinogen oxidase activity
CFI11_RS03815	COG0181	hydroxymethylbilane synthase activity
CFI11_RS03820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFI11_RS03840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_RS03840	COG1648	precorrin-2 dehydrogenase activity
CFI11_RS03845	COG1797	cobyrinic acid a,c-diamide synthase activity
CFI11_RS03850	COG2875	Belongs to the precorrin methyltransferase family
CFI11_RS03865	COG2099	Precorrin-6x reductase
CFI11_RS03940	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS03965	COG1178	ABC-type Fe3 transport system permease component
CFI11_RS03975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFI11_RS03980	COG0583	DNA-binding transcription factor activity
CFI11_RS03985	COG2267	carboxylic ester hydrolase activity
CFI11_RS03990	COG0747	negative chemotaxis
CFI11_RS03995	COG0601	transmembrane transport
CFI11_RS04000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS04010	COG4608	Belongs to the ABC transporter superfamily
CFI11_RS04015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFI11_RS04030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFI11_RS04040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFI11_RS04045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFI11_RS04055	COG0469	pyruvate kinase activity
CFI11_RS04080	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_RS04110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFI11_RS04125	COG0789	Transcriptional regulator
CFI11_RS04145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFI11_RS04150	COG0142	geranyltranstransferase activity
CFI11_RS04160	COG2264	protein methyltransferase activity
CFI11_RS04175	COG0583	DNA-binding transcription factor activity
CFI11_RS04195	COG2818	Glycosylase
CFI11_RS04220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFI11_RS04225	COG0165	Argininosuccinate lyase
CFI11_RS04245	COG0019	diaminopimelate decarboxylase activity
CFI11_RS04260	COG2884	Cell division ATP-binding protein ftsE
CFI11_RS04280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_RS04300	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_RS04320	COG0045	succinate-CoA ligase (ADP-forming) activity
CFI11_RS04330	COG0039	L-malate dehydrogenase activity
CFI11_RS04360	COG2030	dehydratase
CFI11_RS04385	COG0811	peptide transport
CFI11_RS04400	COG3720	iron ion transport
CFI11_RS04405	COG4558	Periplasmic binding protein
CFI11_RS04410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_RS04415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFI11_RS04490	COG0825	malonyl-CoA metabolic process
CFI11_RS04495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS04535	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS04545	COG0583	DNA-binding transcription factor activity
CFI11_RS04560	COG0705	Rhomboid family
CFI11_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS04580	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFI11_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS04605	COG4638	Rieske (2fe-2S)
CFI11_RS04630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_RS04655	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS04660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS04665	COG0601	transmembrane transport
CFI11_RS04670	COG0747	negative chemotaxis
CFI11_RS04680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CFI11_RS04685	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_RS04695	COG1984	allophanate hydrolase subunit 2
CFI11_RS04705	COG0439	Biotin carboxylase
CFI11_RS04715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFI11_RS04720	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS04725	COG1129	ABC transporter
CFI11_RS04730	COG1879	ABC-type sugar transport system periplasmic component
CFI11_RS04740	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFI11_RS04745	COG0697	spore germination
CFI11_RS04760	COG1104	cysteine desulfurase activity
CFI11_RS04770	COG0583	DNA-binding transcription factor activity
CFI11_RS04780	COG0601	transmembrane transport
CFI11_RS04785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS04815	COG0297	glycogen (starch) synthase activity
CFI11_RS04820	COG0483	inositol monophosphate 1-phosphatase activity
CFI11_RS04845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_RS04845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_RS04855	COG1072	(Pantothenic acid kinase))
CFI11_RS04865	COG2217	Heavy metal translocating P-type atpase
CFI11_RS04900	COG1609	Transcriptional regulator
CFI11_RS04910	COG0673	inositol 2-dehydrogenase activity
CFI11_RS04920	COG1175	transmembrane transport
CFI11_RS04925	COG0395	ABC-type sugar transport system, permease component
CFI11_RS04935	COG3842	ATPase activity
CFI11_RS04955	COG1070	Carbohydrate kinase
CFI11_RS04960	COG2115	Belongs to the xylose isomerase family
CFI11_RS04965	COG0747	negative chemotaxis
CFI11_RS04990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS05000	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS05005	COG4608	Belongs to the ABC transporter superfamily
CFI11_RS05015	COG1414	Transcriptional regulator
CFI11_RS05020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFI11_RS05025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFI11_RS05030	COG3616	Alanine racemase, N-terminal domain
CFI11_RS05035	COG2423	ornithine cyclodeaminase activity
CFI11_RS05045	COG3769	mannosylglycerate metabolic process
CFI11_RS05050	COG1215	transferase activity, transferring glycosyl groups
CFI11_RS05060	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFI11_RS05065	COG0830	nickel cation binding
CFI11_RS05070	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFI11_RS05085	COG0804	urea catabolic process
CFI11_RS05110	COG0832	Belongs to the urease beta subunit family
CFI11_RS05115	COG0831	urea catabolic process
CFI11_RS05120	COG0829	nickel cation binding
CFI11_RS05125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_RS05125	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_RS05135	COG0174	glutamine synthetase
CFI11_RS05140	COG2205	protein histidine kinase activity
CFI11_RS05240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFI11_RS05245	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CFI11_RS05250	COG0535	radical SAM domain protein
CFI11_RS05255	COG0535	radical SAM domain protein
CFI11_RS05260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_RS05265	COG1414	Transcriptional regulator
CFI11_RS05285	COG5441	Belongs to the UPF0261 family
CFI11_RS05295	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_RS05325	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_RS05325	COG1024	Enoyl-CoA hydratase
CFI11_RS05330	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS05335	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS05345	COG1024	Enoyl-CoA hydratase
CFI11_RS05350	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS05365	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CFI11_RS05375	COG3639	organic phosphonate transmembrane transporter activity
CFI11_RS05380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_RS05385	COG2188	Transcriptional regulator
CFI11_RS05390	COG3624	Phosphonate C-P lyase system protein PhnG
CFI11_RS05395	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFI11_RS05400	COG3626	phosphonate metabolism
CFI11_RS05405	COG3627	carbon phosphorus lyase activity
CFI11_RS05410	COG2226	methyltransferase
CFI11_RS05410	COG0596	Alpha beta hydrolase
CFI11_RS05410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_RS05415	COG4107	phosphonate C-P lyase system protein PhnK
CFI11_RS05420	COG4778	phosphonate C-P lyase system protein PhnL
CFI11_RS05435	COG3454	Phosphonate metabolism
CFI11_RS05470	COG0588	phosphoglycerate mutase activity
CFI11_RS05475	COG0438	transferase activity, transferring glycosyl groups
CFI11_RS05490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFI11_RS05495	COG0668	transmembrane transport
CFI11_RS05505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS05510	COG0601	transmembrane transport
CFI11_RS05520	COG4172	Belongs to the ABC transporter superfamily
CFI11_RS05540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS05545	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_RS05555	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFI11_RS05560	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFI11_RS05580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFI11_RS05590	COG3002	Belongs to the UPF0753 family
CFI11_RS05595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFI11_RS05610	COG1522	sequence-specific DNA binding
CFI11_RS05615	COG4412	M6 family metalloprotease domain protein
CFI11_RS05615	COG1404	Belongs to the peptidase S8 family
CFI11_RS05635	COG1132	(ABC) transporter
CFI11_RS05640	COG0745	RESPONSE REGULATOR receiver
CFI11_RS05645	COG2205	protein histidine kinase activity
CFI11_RS05650	COG1132	(ABC) transporter
CFI11_RS05650	COG2375	cellular response to nickel ion
CFI11_RS05665	COG0154	amidase activity
CFI11_RS05670	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_RS05690	COG3485	protocatechuate 3,4-dioxygenase
CFI11_RS05695	COG3485	protocatechuate 3,4-dioxygenase
CFI11_RS05700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_RS05705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_RS05730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFI11_RS05735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFI11_RS05740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFI11_RS05765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFI11_RS05780	COG1702	phosphate starvation-inducible protein PhoH
CFI11_RS05785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFI11_RS05790	COG1253	flavin adenine dinucleotide binding
CFI11_RS05795	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFI11_RS05800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFI11_RS05815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFI11_RS05825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFI11_RS05830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFI11_RS05840	COG0539	negative regulation of cytoplasmic translation
CFI11_RS05845	COG0776	regulation of translation
CFI11_RS05855	COG0135	phosphoribosylanthranilate isomerase activity
CFI11_RS05865	COG0133	tryptophan synthase activity
CFI11_RS05895	COG0193	aminoacyl-tRNA hydrolase activity
CFI11_RS05900	COG2329	Antibiotic biosynthesis monooxygenase
CFI11_RS05905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFI11_RS05920	COG1304	FMN binding
CFI11_RS05935	COG2030	dehydratase
CFI11_RS05940	COG0159	tryptophan synthase activity
CFI11_RS05945	COG0012	GTP binding
CFI11_RS05955	COG0577	efflux transmembrane transporter activity
CFI11_RS05955	COG1136	(ABC) transporter
CFI11_RS05965	COG1566	PFAM secretion protein HlyD family protein
CFI11_RS06065	COG0625	glutathione transferase activity
CFI11_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS06090	COG0583	DNA-binding transcription factor activity
CFI11_RS06115	COG4974	Belongs to the 'phage' integrase family
CFI11_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS06175	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_RS06180	COG0022	dehydrogenase e1 component
CFI11_RS06200	COG0583	DNA-binding transcription factor activity
CFI11_RS06220	COG0300	oxidoreductase activity
CFI11_RS06305	COG2197	response regulator
CFI11_RS06315	COG5002	protein histidine kinase activity
CFI11_RS06315	COG0784	Response regulator, receiver
CFI11_RS06315	COG2198	Histidine kinase
CFI11_RS06340	COG0800	Aldolase
CFI11_RS06345	COG3734	2-keto-3-deoxy-galactonokinase
CFI11_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS06360	COG0395	ABC-type sugar transport system, permease component
CFI11_RS06365	COG1175	transmembrane transport
CFI11_RS06375	COG1414	Transcriptional regulator
CFI11_RS06385	COG4136	ATPase activity
CFI11_RS06390	COG4135	transport system, permease component
CFI11_RS06395	COG4134	Bacterial extracellular solute-binding protein
CFI11_RS06420	COG1175	transmembrane transport
CFI11_RS06425	COG0395	ABC-type sugar transport system, permease component
CFI11_RS06430	COG3842	ATPase activity
CFI11_RS06450	COG4221	oxidoreductase activity
CFI11_RS06460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFI11_RS06475	COG0662	Cupin 2, conserved barrel domain protein
CFI11_RS06475	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CFI11_RS06510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFI11_RS06515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFI11_RS06520	COG0287	Prephenate dehydrogenase
CFI11_RS06535	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFI11_RS06560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFI11_RS06570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFI11_RS06575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFI11_RS06580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFI11_RS06585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFI11_RS06590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFI11_RS06625	COG2983	Belongs to the UPF0260 family
CFI11_RS06630	COG0196	riboflavin kinase activity
CFI11_RS06635	COG2030	dehydratase
CFI11_RS06645	COG4176	ABC-type proline glycine betaine transport system permease component
CFI11_RS06650	COG4175	Glycine betaine
CFI11_RS06650	COG3448	diguanylate cyclase activity
CFI11_RS06660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_RS06665	COG1609	Transcriptional regulator
CFI11_RS06670	COG1227	inorganic diphosphatase activity
CFI11_RS06695	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFI11_RS06700	COG0459	protein refolding
CFI11_RS06720	COG3454	Phosphonate metabolism
CFI11_RS06725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFI11_RS06730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFI11_RS06740	COG0071	Belongs to the small heat shock protein (HSP20) family
CFI11_RS06760	COG0529	Catalyzes the synthesis of activated sulfate
CFI11_RS06760	COG2046	Belongs to the sulfate adenylyltransferase family
CFI11_RS06765	COG0492	ferredoxin-NADP+ reductase activity
CFI11_RS06770	COG1522	sequence-specific DNA binding
CFI11_RS06780	COG1496	oxidoreductase activity
CFI11_RS06790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFI11_RS06810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_RS06820	COG1435	thymidine kinase activity
CFI11_RS06825	COG0431	NADPH-dependent FMN reductase
CFI11_RS06850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFI11_RS06855	COG1032	radical SAM domain protein
CFI11_RS06860	COG1719	4-vinyl reductase, 4VR
CFI11_RS06865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_RS06870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFI11_RS06895	COG0346	lactoylglutathione lyase activity
CFI11_RS06905	COG0625	glutathione transferase activity
CFI11_RS06915	COG0778	Nitroreductase
CFI11_RS06950	COG2175	clavaminate synthase activity
CFI11_RS06970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFI11_RS06975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFI11_RS06990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_RS07020	COG0842	Transport permease protein
CFI11_RS07050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_RS07060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFI11_RS07065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFI11_RS07070	COG0251	oxidation-reduction process
CFI11_RS07075	COG0583	DNA-binding transcription factor activity
CFI11_RS07080	COG0589	response to stress
CFI11_RS07090	COG2111	Na H antiporter
CFI11_RS07090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFI11_RS07095	COG2111	Na H antiporter
CFI11_RS07100	COG1006	Multisubunit Na H antiporter MnhC subunit
CFI11_RS07105	COG0651	ATP synthesis coupled electron transport
CFI11_RS07110	COG1863	multisubunit Na H antiporter MnhE subunit
CFI11_RS07115	COG2212	antiporter activity
CFI11_RS07120	COG1320	monovalent cation:proton antiporter activity
CFI11_RS07140	COG0625	glutathione transferase activity
CFI11_RS07145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFI11_RS07150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFI11_RS07160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFI11_RS07170	COG1643	Atp-dependent helicase
CFI11_RS07175	COG1703	isobutyryl-CoA mutase activity
CFI11_RS07180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_RS07210	COG1733	regulation of RNA biosynthetic process
CFI11_RS07225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFI11_RS07240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFI11_RS07245	COG0583	DNA-binding transcription factor activity
CFI11_RS07250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFI11_RS07255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFI11_RS07275	COG0481	GTPase activity
CFI11_RS07290	COG1943	Transposase
CFI11_RS07310	COG0596	Alpha beta hydrolase
CFI11_RS07320	COG3739	integral membrane protein
CFI11_RS07325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFI11_RS07330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFI11_RS07335	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS07340	COG0154	amidase activity
CFI11_RS07350	COG0280	phosphate acetyltransferase
CFI11_RS07350	COG0281	malic enzyme
CFI11_RS07360	COG0295	cytidine deaminase activity
CFI11_RS07365	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFI11_RS07370	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFI11_RS07375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFI11_RS07390	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_RS07410	COG1024	Enoyl-CoA hydratase
CFI11_RS07420	COG0183	Belongs to the thiolase family
CFI11_RS07430	COG0435	Glutathione S-transferase
CFI11_RS07445	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS07450	COG0789	Transcriptional regulator
CFI11_RS07470	COG0534	Mate efflux family protein
CFI11_RS07490	COG0737	Belongs to the 5'-nucleotidase family
CFI11_RS07495	COG2135	peptidase activity
CFI11_RS07505	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFI11_RS07510	COG1984	allophanate hydrolase subunit 2
CFI11_RS07535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_RS07540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS07560	COG3842	ATPase activity
CFI11_RS07575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFI11_RS07585	COG0395	ABC-type sugar transport system, permease component
CFI11_RS07590	COG1175	transmembrane transport
CFI11_RS07595	COG3842	ATPase activity
CFI11_RS07600	COG3842	ATPase activity
CFI11_RS07640	COG1132	(ABC) transporter
CFI11_RS07645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CFI11_RS07650	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS07665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS07675	COG4166	transmembrane transport
CFI11_RS07680	COG1929	Belongs to the glycerate kinase type-1 family
CFI11_RS07685	COG0471	metal ion transport
CFI11_RS07695	COG2379	hydroxypyruvate reductase
CFI11_RS07735	COG3853	Toxic anion resistance protein (TelA)
CFI11_RS07745	COG1187	pseudouridine synthase activity
CFI11_RS07750	COG0590	tRNA wobble adenosine to inosine editing
CFI11_RS07765	COG0385	Bile acid
CFI11_RS07770	COG0490	domain, Protein
CFI11_RS07770	COG0471	metal ion transport
CFI11_RS07775	COG0217	transcriptional regulatory protein
CFI11_RS07795	COG1132	(ABC) transporter
CFI11_RS07800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFI11_RS07810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFI11_RS07820	COG1024	Enoyl-CoA hydratase
CFI11_RS07825	COG0525	valine-tRNA ligase activity
CFI11_RS07850	COG0583	DNA-binding transcription factor activity
CFI11_RS07860	COG2130	NADP-dependent
CFI11_RS07865	COG2130	NADP-dependent
CFI11_RS07875	COG0483	inositol monophosphate 1-phosphatase activity
CFI11_RS07895	COG1522	sequence-specific DNA binding
CFI11_RS07910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_RS07920	COG2353	YceI-like domain
CFI11_RS07925	COG0667	Aldo Keto reductase
CFI11_RS07935	COG3246	L-lysine catabolic process to acetate
CFI11_RS07940	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFI11_RS07940	COG0824	Thioesterase
CFI11_RS08080	COG0297	glycogen (starch) synthase activity
CFI11_RS08155	COG4650	regulator
CFI11_RS08165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFI11_RS08170	COG1494	fructose-1,6-bisphosphatase
CFI11_RS08220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFI11_RS08230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS08235	COG4311	Sarcosine oxidase, delta subunit
CFI11_RS08240	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_RS08240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_RS08255	COG0358	DNA primase activity
CFI11_RS08260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFI11_RS08275	COG0432	Pfam Uncharacterised protein family UPF0047
CFI11_RS08285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_RS08285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFI11_RS08315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFI11_RS08315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFI11_RS08320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFI11_RS08325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFI11_RS08345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFI11_RS08350	COG1304	FMN binding
CFI11_RS08355	COG0210	DNA helicase
CFI11_RS08370	COG2001	Belongs to the MraZ family
CFI11_RS08375	COG0275	rRNA processing
CFI11_RS08390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFI11_RS08395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFI11_RS08400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFI11_RS08415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFI11_RS08420	COG2081	HI0933 family
CFI11_RS08430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFI11_RS08435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFI11_RS08445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFI11_RS08450	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFI11_RS08455	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFI11_RS08460	COG0849	cell division
CFI11_RS08465	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFI11_RS08470	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CFI11_RS08475	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_RS08480	COG0497	DNA recombination
CFI11_RS08550	COG0235	Class ii aldolase
CFI11_RS08565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFI11_RS08575	COG0596	Alpha beta hydrolase
CFI11_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS08590	COG0308	aminopeptidase N
CFI11_RS08600	COG0415	Belongs to the DNA photolyase family
CFI11_RS08615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFI11_RS08625	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFI11_RS08630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFI11_RS08630	COG2010	Cytochrome c
CFI11_RS08645	COG3483	tryptophan 2,3-dioxygenase activity
CFI11_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS08685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFI11_RS08710	COG2391	methyltransferase activity
CFI11_RS08720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS08725	COG0601	transmembrane transport
CFI11_RS08735	COG4172	Belongs to the ABC transporter superfamily
CFI11_RS08745	COG1473	amidohydrolase
CFI11_RS08750	COG1473	amidohydrolase
CFI11_RS08760	COG1519	Transferase
CFI11_RS08765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFI11_RS08790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFI11_RS08795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_RS08800	COG0546	phosphoglycolate phosphatase activity
CFI11_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS08815	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS08820	COG3047	cAMP biosynthetic process
CFI11_RS08825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFI11_RS08845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFI11_RS08855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_RS08865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_RS08870	COG0649	NAD binding
CFI11_RS08880	COG3743	rRNA binding
CFI11_RS08880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFI11_RS08930	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFI11_RS08940	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFI11_RS08960	COG0713	ATP synthesis coupled electron transport
CFI11_RS08975	COG1007	ATP synthesis coupled electron transport
CFI11_RS08985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CFI11_RS08995	COG0513	Belongs to the DEAD box helicase family
CFI11_RS09025	COG0243	molybdopterin cofactor binding
CFI11_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS09040	COG4335	DNA alkylation repair
CFI11_RS09045	COG3842	ATPase activity
CFI11_RS09050	COG2226	methyltransferase
CFI11_RS09060	COG2378	regulation of single-species biofilm formation
CFI11_RS09070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFI11_RS09075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFI11_RS09080	COG0805	protein transport
CFI11_RS09095	COG1388	LysM domain
CFI11_RS09095	COG0739	heme binding
CFI11_RS09100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFI11_RS09105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFI11_RS09110	COG4221	oxidoreductase activity
CFI11_RS09120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFI11_RS09145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_RS09155	COG1127	ABC transporter
CFI11_RS09160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFI11_RS09165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFI11_RS09175	COG0305	Participates in initiation and elongation during chromosome replication
CFI11_RS09180	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFI11_RS09185	COG0418	dihydroorotase activity
CFI11_RS09225	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFI11_RS09250	COG2814	Major facilitator Superfamily
CFI11_RS09260	COG0367	asparagine synthase
CFI11_RS09270	COG0506	proline dehydrogenase activity
CFI11_RS09280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFI11_RS09290	COG2814	Major facilitator Superfamily
CFI11_RS09305	COG0175	sulfate reduction
CFI11_RS09310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFI11_RS09320	COG1648	precorrin-2 dehydrogenase activity
CFI11_RS09320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFI11_RS09325	COG1522	sequence-specific DNA binding
CFI11_RS09340	COG2204	response regulator
CFI11_RS09345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS09350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFI11_RS09355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS09360	COG0149	triose-phosphate isomerase activity
CFI11_RS09370	COG0316	Belongs to the HesB IscA family
CFI11_RS09380	COG2151	metal-sulfur cluster biosynthetic enzyme
CFI11_RS09385	COG0343	queuine tRNA-ribosyltransferase activity
CFI11_RS09390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFI11_RS09405	COG0406	alpha-ribazole phosphatase activity
CFI11_RS09410	COG1741	Belongs to the pirin family
CFI11_RS09450	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_RS09460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFI11_RS09475	COG0436	Aminotransferase
CFI11_RS09485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFI11_RS09495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFI11_RS09500	COG0154	amidase activity
CFI11_RS09515	COG4638	Rieske (2fe-2S)
CFI11_RS09530	COG0440	acetolactate synthase activity
CFI11_RS09545	COG0028	Belongs to the TPP enzyme family
CFI11_RS09565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFI11_RS09575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS09585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_RS09620	COG0346	lactoylglutathione lyase activity
CFI11_RS09625	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFI11_RS09725	COG4397	Mu-like prophage major head subunit gpT
CFI11_RS09770	COG4373	Mu-like prophage FluMu protein gp28
CFI11_RS09910	COG2801	Transposase and inactivated derivatives
CFI11_RS09950	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFI11_RS09975	COG2124	cytochrome p450
CFI11_RS10010	COG3268	Saccharopine dehydrogenase
CFI11_RS10045	COG0542	response to heat
CFI11_RS10055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_RS10080	COG0316	Belongs to the HesB IscA family
CFI11_RS10085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFI11_RS10090	COG0018	arginyl-trna synthetase
CFI11_RS10100	COG1472	Belongs to the glycosyl hydrolase 3 family
CFI11_RS10105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFI11_RS10110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFI11_RS10130	COG0717	Belongs to the dCTP deaminase family
CFI11_RS10145	COG0776	regulation of translation
CFI11_RS10150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFI11_RS10155	COG0416	fatty acid biosynthetic process
CFI11_RS10160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFI11_RS10180	COG0488	(ABC) transporter
CFI11_RS10205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFI11_RS10210	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFI11_RS10240	COG0148	phosphopyruvate hydratase activity
CFI11_RS10245	COG0697	spore germination
CFI11_RS10260	COG0513	Belongs to the DEAD box helicase family
CFI11_RS10275	COG0697	spore germination
CFI11_RS10280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFI11_RS10305	COG3956	TIGRFAM MazG family protein
CFI11_RS10310	COG1473	amidohydrolase
CFI11_RS10315	COG0010	Belongs to the arginase family
CFI11_RS10335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFI11_RS10340	COG2890	protein-(glutamine-N5) methyltransferase activity
CFI11_RS10350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFI11_RS10355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFI11_RS10365	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFI11_RS10380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFI11_RS10390	COG3577	Aspartyl protease
CFI11_RS10395	COG0488	(ABC) transporter
CFI11_RS10400	COG0105	UTP biosynthetic process
CFI11_RS10455	COG0215	cysteine-tRNA ligase activity
CFI11_RS10460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_RS10470	COG2814	Major facilitator Superfamily
CFI11_RS10485	COG1187	pseudouridine synthase activity
CFI11_RS10495	COG2423	ornithine cyclodeaminase activity
CFI11_RS10500	COG0010	Belongs to the arginase family
CFI11_RS10510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFI11_RS10515	COG1238	metal cluster binding
CFI11_RS10530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_RS10555	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS10560	COG4536	flavin adenine dinucleotide binding
CFI11_RS10565	COG4974	Belongs to the 'phage' integrase family
CFI11_RS10575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFI11_RS10580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFI11_RS10590	COG0629	single-stranded DNA binding
CFI11_RS10595	COG1196	nuclear chromosome segregation
CFI11_RS10595	COG0741	lytic transglycosylase activity
CFI11_RS10595	COG0739	heme binding
CFI11_RS10620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS10625	COG0601	transmembrane transport
CFI11_RS10640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFI11_RS10645	COG0528	UMP kinase activity
CFI11_RS10650	COG0233	cytoplasmic translational termination
CFI11_RS10655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFI11_RS10665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFI11_RS10670	COG0750	zinc metalloprotease
CFI11_RS10675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_RS10685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFI11_RS10690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_RS10695	COG3494	Protein of unknown function (DUF1009)
CFI11_RS10700	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_RS10725	COG0482	sulfurtransferase activity
CFI11_RS10735	COG0745	RESPONSE REGULATOR receiver
CFI11_RS10740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFI11_RS10755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFI11_RS10760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_RS10765	COG2264	protein methyltransferase activity
CFI11_RS10770	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFI11_RS10795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFI11_RS10800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFI11_RS10805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFI11_RS10815	COG1309	transcriptional regulator
CFI11_RS10820	COG2326	polyphosphate kinase activity
CFI11_RS10825	COG0596	Alpha beta hydrolase
CFI11_RS10830	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFI11_RS10850	COG0697	spore germination
CFI11_RS10855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_RS10855	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_RS10860	COG5598	trimethylamine methyltransferase
CFI11_RS10880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFI11_RS10885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CFI11_RS10890	COG2867	negative regulation of translational initiation
CFI11_RS10900	COG1546	Belongs to the CinA family
CFI11_RS10905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFI11_RS10910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFI11_RS10910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFI11_RS10915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFI11_RS10920	COG3852	Histidine kinase
CFI11_RS10925	COG2204	response regulator
CFI11_RS10930	COG5000	phosphorelay sensor kinase activity
CFI11_RS10935	COG2204	response regulator
CFI11_RS10945	COG0569	domain protein
CFI11_RS10950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_RS10955	COG1923	regulation of RNA biosynthetic process
CFI11_RS10960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFI11_RS10970	COG2084	Dehydrogenase
CFI11_RS10995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFI11_RS11005	COG2814	Major facilitator Superfamily
CFI11_RS11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_RS11050	COG4166	transmembrane transport
CFI11_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS11075	COG2313	pseudouridylate synthase activity
CFI11_RS11095	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFI11_RS11100	COG0352	thiamine-phosphate diphosphorylase activity
CFI11_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS11115	COG1612	heme a metabolic process
CFI11_RS11120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CFI11_RS11135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFI11_RS11140	COG5425	PFAM Usg family protein
CFI11_RS11145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFI11_RS11155	COG0166	Belongs to the GPI family
CFI11_RS11160	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS11185	COG0516	GMP reductase activity
CFI11_RS11185	COG0517	IMP dehydrogenase activity
CFI11_RS11205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFI11_RS11210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFI11_RS11220	COG1217	gtp-binding protein TYPA
CFI11_RS11230	COG0538	isocitrate dehydrogenase activity
CFI11_RS11245	COG2945	thiolester hydrolase activity
CFI11_RS11250	COG1959	2 iron, 2 sulfur cluster binding
CFI11_RS11255	COG1104	cysteine desulfurase activity
CFI11_RS11260	COG0719	Fe-S assembly protein
CFI11_RS11280	COG0396	ATPase activity
CFI11_RS11285	COG0719	Fe-S assembly protein
CFI11_RS11300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_RS11310	COG0583	DNA-binding transcription factor activity
CFI11_RS11325	COG0702	epimerase
CFI11_RS11330	COG0596	Alpha beta hydrolase
CFI11_RS11335	COG0583	DNA-binding transcription factor activity
CFI11_RS11345	COG2948	multi-organism process
CFI11_RS11355	COG3701	Conjugal transfer protein
CFI11_RS11360	COG3846	protein secretion by the type IV secretion system
CFI11_RS11375	COG3451	type IV secretory pathway VirB4
CFI11_RS11390	COG4962	Type ii secretion system protein e
CFI11_RS11395	COG0583	DNA-binding transcription factor activity
CFI11_RS11430	COG0741	lytic transglycosylase activity
CFI11_RS11480	COG5489	Protein of unknown function (DUF736)
CFI11_RS11565	COG4974	Belongs to the 'phage' integrase family
CFI11_RS11570	COG3108	Peptidase M15
CFI11_RS11575	COG2989	Protein conserved in bacteria
CFI11_RS11580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFI11_RS11585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFI11_RS11600	COG0433	COG0433 Predicted ATPase
CFI11_RS11650	COG2133	pyrroloquinoline quinone binding
CFI11_RS11665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFI11_RS11675	COG1561	YicC-like family, N-terminal region
CFI11_RS11680	COG0194	GDP metabolic process
CFI11_RS11695	COG5002	protein histidine kinase activity
CFI11_RS11705	COG0573	inorganic phosphate transmembrane transporter activity
CFI11_RS11715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFI11_RS11720	COG0704	Plays a role in the regulation of phosphate uptake
CFI11_RS11725	COG0745	RESPONSE REGULATOR receiver
CFI11_RS11730	COG0583	DNA-binding transcription factor activity
CFI11_RS11735	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS11745	COG0028	Belongs to the TPP enzyme family
CFI11_RS11750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_RS11765	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CFI11_RS11770	COG2943	transferase activity, transferring hexosyl groups
CFI11_RS11785	COG0729	surface antigen
CFI11_RS11810	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS11825	COG1946	Acyl-CoA thioesterase
CFI11_RS11830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_RS11845	COG0625	glutathione transferase activity
CFI11_RS11885	COG0583	DNA-binding transcription factor activity
CFI11_RS11900	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS11915	COG1131	(ABC) transporter
CFI11_RS11960	COG0183	Belongs to the thiolase family
CFI11_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS11975	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS11980	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS11995	COG2130	NADP-dependent
CFI11_RS12005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFI11_RS12010	COG2771	luxR family
CFI11_RS12020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFI11_RS12025	COG0052	Belongs to the universal ribosomal protein uS2 family
CFI11_RS12050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFI11_RS12055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFI11_RS12060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFI11_RS12090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFI11_RS12095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFI11_RS12095	COG3743	rRNA binding
CFI11_RS12125	COG3811	Belongs to the UPF0386 family
CFI11_RS12130	COG0673	inositol 2-dehydrogenase activity
CFI11_RS12145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_RS12160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFI11_RS12170	COG0248	Ppx GppA phosphatase
CFI11_RS12175	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFI11_RS12205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_RS12205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFI11_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS12275	COG1129	ABC transporter
CFI11_RS12285	COG1335	isochorismatase
CFI11_RS12305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_RS12310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_RS12315	COG1802	Transcriptional regulator
CFI11_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS12340	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS12345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS12355	COG0747	negative chemotaxis
CFI11_RS12410	COG1846	Transcriptional regulator
CFI11_RS12450	COG1309	transcriptional regulator
CFI11_RS12460	COG0287	Prephenate dehydrogenase
CFI11_RS12470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFI11_RS12485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_RS12495	COG0583	DNA-binding transcription factor activity
CFI11_RS12505	COG0435	Glutathione S-transferase
CFI11_RS12525	COG1177	transmembrane transport
CFI11_RS12530	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_RS12535	COG3842	ATPase activity
CFI11_RS12580	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_RS12590	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFI11_RS12590	COG3264	Mechanosensitive ion channel
CFI11_RS12600	COG0494	nUDIX hydrolase
CFI11_RS12610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_RS12615	COG0415	Belongs to the DNA photolyase family
CFI11_RS12620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_RS12625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFI11_RS12630	COG0604	alcohol dehydrogenase
CFI11_RS12635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_RS12655	COG2186	Transcriptional regulator
CFI11_RS12700	COG0114	fumarate hydratase activity
CFI11_RS12720	COG3588	fructose-bisphosphate aldolase
CFI11_RS12725	COG2124	cytochrome p450
CFI11_RS12735	COG0785	Cytochrome C biogenesis protein
CFI11_RS12740	COG0425	Belongs to the sulfur carrier protein TusA family
CFI11_RS12745	COG1530	ribonuclease E activity
CFI11_RS12760	COG2204	response regulator
CFI11_RS12770	COG0047	phosphoribosylformylglycinamidine synthase activity
CFI11_RS12775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFI11_RS12780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFI11_RS12790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFI11_RS12790	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFI11_RS12795	COG0646	methionine synthase
CFI11_RS12795	COG1410	methionine synthase
CFI11_RS12805	COG5012	cobalamin binding
CFI11_RS12815	COG2166	iron-sulfur cluster assembly
CFI11_RS12825	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFI11_RS12830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFI11_RS12835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFI11_RS12855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFI11_RS12870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFI11_RS12885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_RS12885	COG2169	Transcriptional regulator
CFI11_RS12920	COG1192	Involved in chromosome partitioning
CFI11_RS12940	COG3772	lysozyme
CFI11_RS13055	COG4695	Portal protein
CFI11_RS13125	COG0582	viral genome integration into host DNA
CFI11_RS13200	COG1278	Cold shock
CFI11_RS13205	COG0259	pyridoxamine-phosphate oxidase activity
CFI11_RS13210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFI11_RS13215	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS13220	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS13225	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFI11_RS13240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFI11_RS13260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFI11_RS13265	COG0134	indole-3-glycerol-phosphate synthase activity
CFI11_RS13270	COG0315	cyclic pyranopterin monophosphate synthase activity
CFI11_RS13275	COG0303	'Molybdopterin
CFI11_RS13280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFI11_RS13285	COG2333	competence protein COMEC
CFI11_RS13285	COG0658	competence protein
CFI11_RS13290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFI11_RS13295	COG0372	Belongs to the citrate synthase family
CFI11_RS13320	COG1024	Enoyl-CoA hydratase
CFI11_RS13325	COG3088	subunit of a heme lyase
CFI11_RS13330	COG1138	Cytochrome C-type biogenesis protein
CFI11_RS13345	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFI11_RS13350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFI11_RS13355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFI11_RS13385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFI11_RS13400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFI11_RS13415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFI11_RS13425	COG2354	Protein conserved in bacteria
CFI11_RS13435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFI11_RS13470	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS13485	COG3287	FIST C domain
CFI11_RS13485	COG2199	diguanylate cyclase activity
CFI11_RS13485	COG2200	EAL domain
CFI11_RS13495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFI11_RS13505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFI11_RS13520	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFI11_RS13530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFI11_RS13535	COG2833	Protein of unknown function (DUF455)
CFI11_RS13540	COG0739	heme binding
CFI11_RS13550	COG0477	Major facilitator Superfamily
CFI11_RS13570	COG0126	phosphoglycerate kinase activity
CFI11_RS13575	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CFI11_RS13580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFI11_RS13585	COG0022	dehydrogenase e1 component
CFI11_RS13585	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_RS13590	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_RS13675	COG4695	Portal protein
CFI11_RS13690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFI11_RS13695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFI11_RS13705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFI11_RS13715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFI11_RS13725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFI11_RS13730	COG3038	cytochrome b561
CFI11_RS13735	COG2353	YceI-like domain
CFI11_RS13745	COG0360	Binds together with S18 to 16S ribosomal RNA
CFI11_RS13750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFI11_RS13755	COG0359	binds to the 23S rRNA
CFI11_RS13760	COG3655	Transcriptional regulator
CFI11_RS13785	COG0737	Belongs to the 5'-nucleotidase family
CFI11_RS13790	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFI11_RS13810	COG1840	ABC-type Fe3 transport system, periplasmic component
CFI11_RS13855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFI11_RS13865	COG3609	addiction module antidote protein, CC2985 family
CFI11_RS13920	COG1686	Belongs to the peptidase S11 family
CFI11_RS13950	COG0513	Belongs to the DEAD box helicase family
CFI11_RS13955	COG1278	Cold shock
CFI11_RS13975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFI11_RS13985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_RS14095	COG0321	lipoyl(octanoyl) transferase activity
CFI11_RS14130	COG0505	Belongs to the CarA family
CFI11_RS14140	COG1802	Transcriptional regulator
CFI11_RS14170	COG1522	sequence-specific DNA binding
CFI11_RS14180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFI11_RS14190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFI11_RS14195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFI11_RS14200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFI11_RS14210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFI11_RS14210	COG0574	Belongs to the PEP-utilizing enzyme family
CFI11_RS14215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS14230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_RS14235	COG0563	adenylate kinase activity
CFI11_RS14245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFI11_RS14250	COG0517	IMP dehydrogenase activity
CFI11_RS14250	COG0516	GMP reductase activity
CFI11_RS14260	COG2176	DNA-directed DNA polymerase activity
CFI11_RS14260	COG5002	protein histidine kinase activity
CFI11_RS14265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFI11_RS14280	COG0489	protein tyrosine kinase activity
CFI11_RS14320	COG3383	formate dehydrogenase (NAD+) activity
CFI11_RS14320	COG0243	molybdopterin cofactor binding
CFI11_RS14325	COG0437	4 iron, 4 sulfur cluster binding
CFI11_RS14350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS14355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS14380	COG1309	transcriptional regulator
CFI11_RS14435	COG2873	o-acetylhomoserine
CFI11_RS14440	COG2968	Membrane
CFI11_RS14470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFI11_RS14475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFI11_RS14480	COG1329	Transcriptional regulator
CFI11_RS14485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFI11_RS14520	COG1793	dna ligase
CFI11_RS14555	COG0564	pseudouridine synthase activity
CFI11_RS14570	COG0456	acetyltransferase
CFI11_RS14595	COG0640	Transcriptional regulator
CFI11_RS14610	COG1126	abc transporter atp-binding protein
CFI11_RS14635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS14655	COG0626	cystathionine gamma-synthase activity
CFI11_RS14665	COG0765	amino acid transport
CFI11_RS14670	COG4597	amino acid ABC transporter
CFI11_RS14675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFI11_RS14765	COG0131	Imidazoleglycerol-phosphate dehydratase
CFI11_RS14770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFI11_RS14795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFI11_RS14810	COG0107	imidazoleglycerol-phosphate synthase activity
CFI11_RS14830	COG1832	CoA-binding protein
CFI11_RS14845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFI11_RS14865	COG1175	transmembrane transport
CFI11_RS14895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFI11_RS14895	COG1618	nucleotide phosphatase activity, acting on free nucleotides
CFI11_RS14900	COG0303	'Molybdopterin
CFI11_RS14925	COG1858	cytochrome C peroxidase
CFI11_RS14940	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFI11_RS14945	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS14975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS14995	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFI11_RS15005	COG3842	ATPase activity
CFI11_RS15040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_RS15045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_RS15050	COG1120	ATPase activity
CFI11_RS15055	COG1132	(ABC) transporter
CFI11_RS15060	COG4774	siderophore transport
CFI11_RS15075	COG1309	transcriptional regulator
CFI11_RS15085	COG1846	Transcriptional regulator
CFI11_RS15095	COG0251	oxidation-reduction process
CFI11_RS15110	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFI11_RS15115	COG4149	molybdate abc transporter
CFI11_RS15120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFI11_RS15125	COG3750	Belongs to the UPF0335 family
CFI11_RS15155	COG5002	protein histidine kinase activity
CFI11_RS15165	COG0745	RESPONSE REGULATOR receiver
CFI11_RS15170	COG3800	Transcriptional regulator
CFI11_RS15170	COG1396	sequence-specific DNA binding
CFI11_RS15180	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS15195	COG0410	ABC transporter
CFI11_RS15210	COG0511	ligase activity, forming carbon-carbon bonds
CFI11_RS15215	COG0439	Biotin carboxylase
CFI11_RS15220	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFI11_RS15245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_RS15250	COG0740	serine-type endopeptidase activity
CFI11_RS15270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS15290	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFI11_RS15300	COG0022	dehydrogenase e1 component
CFI11_RS15320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFI11_RS15325	COG0737	Belongs to the 5'-nucleotidase family
CFI11_RS15330	COG3258	Cytochrome c
CFI11_RS15355	COG0785	Cytochrome C biogenesis protein
CFI11_RS15375	COG2391	methyltransferase activity
CFI11_RS15385	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CFI11_RS15400	COG3246	L-lysine catabolic process to acetate
CFI11_RS15425	COG0477	Major facilitator Superfamily
CFI11_RS15445	COG1686	Belongs to the peptidase S11 family
CFI11_RS15450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFI11_RS15460	COG0084	hydrolase, TatD family'
CFI11_RS15465	COG1234	tRNA 3'-trailer cleavage
CFI11_RS15480	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CFI11_RS15490	COG1116	anion transmembrane transporter activity
CFI11_RS15495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS15500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFI11_RS15505	COG3604	Transcriptional regulator
CFI11_RS15515	COG1131	(ABC) transporter
CFI11_RS15610	COG0523	cobalamin synthesis protein
CFI11_RS15615	COG0523	cobalamin synthesis protein
CFI11_RS15655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFI11_RS15665	COG0589	response to stress
CFI11_RS15670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_RS15695	COG0747	negative chemotaxis
CFI11_RS15700	COG0601	transmembrane transport
CFI11_RS15705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS15710	COG0405	Gamma-glutamyltransferase
CFI11_RS15720	COG2186	Transcriptional regulator
CFI11_RS15735	COG4166	transmembrane transport
CFI11_RS15740	COG0601	transmembrane transport
CFI11_RS15745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS15755	COG1473	amidohydrolase
CFI11_RS15770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFI11_RS15775	COG3608	succinylglutamate desuccinylase aspartoacylase
CFI11_RS15775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFI11_RS15805	COG5001	Diguanylate cyclase
CFI11_RS15805	COG3300	MHYT domain
CFI11_RS15830	COG0601	transmembrane transport
CFI11_RS15835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS15870	COG2951	lytic endotransglycosylase activity
CFI11_RS15880	COG3209	COG3209 Rhs family protein
CFI11_RS15905	COG0673	inositol 2-dehydrogenase activity
CFI11_RS15925	COG0006	proline dipeptidase activity
CFI11_RS15955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFI11_RS15960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFI11_RS15965	COG0751	glycine-tRNA ligase activity
CFI11_RS15975	COG0752	glycyl-tRNA synthetase alpha subunit
CFI11_RS15990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_RS16010	COG1469	GTP cyclohydrolase I activity
CFI11_RS16025	COG0625	glutathione transferase activity
CFI11_RS16030	COG2917	probably involved in intracellular septation
CFI11_RS16040	COG0552	protein localization to endoplasmic reticulum
CFI11_RS16065	COG0151	Belongs to the GarS family
CFI11_RS16095	COG0330	HflC and HflK could
CFI11_RS16110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFI11_RS16125	COG1760	l-serine dehydratase
CFI11_RS16150	COG0789	Transcriptional regulator
CFI11_RS16160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFI11_RS16165	COG2746	aminoglycoside 3-N-acetyltransferase activity
CFI11_RS16175	COG0189	ligase activity
CFI11_RS16200	COG0504	CTP synthase activity
CFI11_RS16245	COG4215	(ABC) transporter
CFI11_RS16255	COG0174	glutamine synthetase
CFI11_RS16260	COG0519	Catalyzes the synthesis of GMP from XMP
CFI11_RS16260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFI11_RS16265	COG0174	glutamine synthetase
CFI11_RS16270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS16275	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFI11_RS16295	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFI11_RS16325	COG0640	Transcriptional regulator
CFI11_RS16350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFI11_RS16360	COG3220	belongs to the UPF0276 family
CFI11_RS16380	COG1393	Belongs to the ArsC family
CFI11_RS16385	COG1278	Cold shock
CFI11_RS16405	COG2124	cytochrome p450
CFI11_RS16410	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CFI11_RS16435	COG1846	Transcriptional regulator
CFI11_RS16460	COG0534	Mate efflux family protein
CFI11_RS16465	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFI11_RS16480	COG0305	Participates in initiation and elongation during chromosome replication
CFI11_RS16485	COG0596	Alpha beta hydrolase
CFI11_RS16495	COG2268	Band 7 protein
CFI11_RS16510	COG0187	DNA topoisomerase II activity
CFI11_RS16545	COG2010	Cytochrome c
CFI11_RS16555	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFI11_RS16560	COG1136	(ABC) transporter
CFI11_RS16585	COG0442	prolyl-tRNA aminoacylation
CFI11_RS16590	COG0628	permease
CFI11_RS16600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFI11_RS16610	COG0248	Ppx GppA phosphatase
CFI11_RS16625	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CFI11_RS16640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFI11_RS16640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFI11_RS16655	COG4770	biotin carboxylase activity
CFI11_RS16690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFI11_RS16700	COG1396	sequence-specific DNA binding
CFI11_RS16700	COG3800	Transcriptional regulator
CFI11_RS16720	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_RS16725	COG3119	arylsulfatase activity
CFI11_RS16730	COG1309	transcriptional regulator
CFI11_RS16750	COG4175	Glycine betaine
CFI11_RS16775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFI11_RS16790	COG1492	cobalamin metabolic process
CFI11_RS16805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFI11_RS16845	COG2072	flavoprotein involved in K transport
CFI11_RS16860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFI11_RS16870	COG2986	histidine ammonia-lyase
CFI11_RS16875	COG1228	amidohydrolase
CFI11_RS16880	COG0471	metal ion transport
CFI11_RS16880	COG3273	potassium ion transport
CFI11_RS16890	COG1692	metallophosphoesterase
CFI11_RS16895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFI11_RS16900	COG2239	Acts as a magnesium transporter
CFI11_RS16905	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_RS16930	COG0583	DNA-binding transcription factor activity
CFI11_RS16940	COG0670	Belongs to the BI1 family
CFI11_RS16955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFI11_RS16985	COG0154	amidase activity
CFI11_RS16990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFI11_RS16995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_RS17005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFI11_RS17010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFI11_RS17050	COG0659	secondary active sulfate transmembrane transporter activity
CFI11_RS17055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFI11_RS17060	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS17065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFI11_RS17070	COG0277	FAD linked oxidase domain protein
CFI11_RS17085	COG0612	Peptidase, M16
CFI11_RS17105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFI11_RS17110	COG0109	protoheme IX farnesyltransferase activity
CFI11_RS17120	COG0312	modulator of DNA gyrase
CFI11_RS17130	COG0758	DNA mediated transformation
CFI11_RS17135	COG1754	DNA topoisomerase type I activity
CFI11_RS17135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFI11_RS17145	COG3920	Histidine kinase
CFI11_RS17175	COG4964	Belongs to the GSP D family
CFI11_RS17230	COG1201	RNA secondary structure unwinding
CFI11_RS17245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFI11_RS17255	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CFI11_RS17265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFI11_RS17270	COG0037	tRNA processing
CFI11_RS17280	COG2885	chlorophyll binding
CFI11_RS17305	COG0824	Thioesterase
CFI11_RS17315	COG2255	four-way junction helicase activity
CFI11_RS17320	COG0632	four-way junction helicase activity
CFI11_RS17340	COG2264	protein methyltransferase activity
CFI11_RS17355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFI11_RS17365	COG4974	Belongs to the 'phage' integrase family
CFI11_RS17370	COG1183	phosphatidylcholine synthase activity
CFI11_RS17380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_RS17390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFI11_RS17395	COG0492	ferredoxin-NADP+ reductase activity
CFI11_RS17395	COG3118	belongs to the thioredoxin family
CFI11_RS17400	COG3768	UPF0283 membrane protein
CFI11_RS17410	COG3106	COG3106 Predicted ATPase
CFI11_RS17415	COG0101	tRNA pseudouridine synthase activity
CFI11_RS17440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFI11_RS17440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFI11_RS17445	COG0509	glycine decarboxylation via glycine cleavage system
CFI11_RS17450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_RS17470	COG0251	oxidation-reduction process
CFI11_RS17480	COG1129	ABC transporter
CFI11_RS17510	COG1024	Enoyl-CoA hydratase
CFI11_RS17520	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS17545	COG1796	DNA polymerase
CFI11_RS17545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CFI11_RS17550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFI11_RS17580	COG2070	2-Nitropropane dioxygenase
CFI11_RS17620	COG0784	Response regulator, receiver
CFI11_RS17620	COG4191	Histidine kinase
CFI11_RS17630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFI11_RS17645	COG2022	thiamine diphosphate biosynthetic process
CFI11_RS17655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFI11_RS17660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFI11_RS17710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFI11_RS17715	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFI11_RS17720	COG0124	histidyl-tRNA synthetase
CFI11_RS17725	COG1024	Enoyl-CoA hydratase
CFI11_RS17750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFI11_RS17760	COG3845	ABC transporter
CFI11_RS17765	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS17770	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS17780	COG0517	IMP dehydrogenase activity
CFI11_RS17785	COG0667	Aldo Keto reductase
CFI11_RS17805	COG0277	FAD linked oxidase domain protein
CFI11_RS17810	COG0405	Gamma-glutamyltransferase
CFI11_RS17825	COG0596	Alpha beta hydrolase
CFI11_RS17830	COG0604	alcohol dehydrogenase
CFI11_RS17845	COG0789	Transcriptional regulator
CFI11_RS17865	COG3591	Belongs to the peptidase S1B family
CFI11_RS17865	COG1864	DNA RNA non-specific endonuclease
CFI11_RS17870	COG1917	Cupin 2, conserved barrel domain protein
CFI11_RS17870	COG2207	Transcriptional regulator
CFI11_RS17880	COG3842	ATPase activity
CFI11_RS17885	COG0395	ABC-type sugar transport system, permease component
CFI11_RS17895	COG1653	transport
CFI11_RS17900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS17905	COG1116	anion transmembrane transporter activity
CFI11_RS17915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS17920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_RS17925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFI11_RS17930	COG0028	Belongs to the TPP enzyme family
CFI11_RS17935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFI11_RS17940	COG2855	membrane
CFI11_RS17945	COG0243	molybdopterin cofactor binding
CFI11_RS17955	COG0437	4 iron, 4 sulfur cluster binding
CFI11_RS17965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFI11_RS17970	COG0741	lytic transglycosylase activity
CFI11_RS17980	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFI11_RS17980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS17990	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFI11_RS18005	COG2885	chlorophyll binding
CFI11_RS18010	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS18015	COG2169	Transcriptional regulator
CFI11_RS18015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFI11_RS18020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFI11_RS18025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFI11_RS18035	COG1051	belongs to the nudix hydrolase family
CFI11_RS18040	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_RS18040	COG1902	pentaerythritol trinitrate reductase activity
CFI11_RS18075	COG0583	DNA-binding transcription factor activity
CFI11_RS18095	COG1546	Belongs to the CinA family
CFI11_RS18095	COG1058	Belongs to the CinA family
CFI11_RS18100	COG1489	DNA binding
CFI11_RS18105	COG0024	Methionine aminopeptidase
CFI11_RS18115	COG0742	ribosomal rna small subunit methyltransferase
CFI11_RS18125	COG0678	peroxiredoxin activity
CFI11_RS18130	COG3920	Histidine kinase
CFI11_RS18135	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFI11_RS18155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_RS18160	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFI11_RS18165	COG2853	Lipoprotein
CFI11_RS18185	COG0004	ammonium transporteR
CFI11_RS18195	COG2897	thiosulfate sulfurtransferase activity
CFI11_RS18205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFI11_RS18280	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_RS18295	COG3591	Belongs to the peptidase S1B family
CFI11_RS18300	COG0247	lactate metabolic process
CFI11_RS18310	COG0277	FAD linked oxidase domain protein
CFI11_RS18315	COG0277	FAD linked oxidase domain protein
CFI11_RS18325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFI11_RS18330	COG0799	negative regulation of ribosome biogenesis
CFI11_RS18340	COG3264	Mechanosensitive ion channel
CFI11_RS18340	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFI11_RS18365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFI11_RS18370	COG0066	3-isopropylmalate dehydratase activity
CFI11_RS18395	COG0473	3-isopropylmalate dehydrogenase activity
CFI11_RS18415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFI11_RS18415	COG3008	intermembrane lipid transfer
CFI11_RS18420	COG2995	paraquat-inducible protein a
CFI11_RS18435	COG2188	Transcriptional regulator
CFI11_RS18440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS18455	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFI11_RS18460	COG1530	ribonuclease E activity
CFI11_RS18470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFI11_RS18475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_RS18500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFI11_RS18510	COG0454	-acetyltransferase
CFI11_RS18510	COG0456	acetyltransferase
CFI11_RS18515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFI11_RS18520	COG5328	Belongs to the UPF0262 family
CFI11_RS18540	COG1959	2 iron, 2 sulfur cluster binding
CFI11_RS18545	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFI11_RS18575	COG1404	Belongs to the peptidase S8 family
CFI11_RS18600	COG1414	Transcriptional regulator
CFI11_RS18655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFI11_RS18665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFI11_RS18670	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFI11_RS18675	COG4133	protoheme IX ABC transporter activity
CFI11_RS18680	COG3737	Protein of unknown function (DUF498/DUF598)
CFI11_RS18685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFI11_RS18690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFI11_RS18695	COG1862	Preprotein translocase
CFI11_RS18705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFI11_RS18720	COG3239	Fatty acid desaturase
CFI11_RS18725	COG1160	GTP binding
CFI11_RS18745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFI11_RS18750	COG5265	(ABC) transporter
CFI11_RS18765	COG2962	Rard protein
CFI11_RS18775	COG1408	metallophosphoesterase
CFI11_RS18795	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFI11_RS18795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFI11_RS18820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFI11_RS18825	COG4235	cytochrome complex assembly
CFI11_RS18830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFI11_RS18845	COG0730	response to heat
CFI11_RS18850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFI11_RS18890	COG3038	cytochrome b561
CFI11_RS18935	COG0501	Belongs to the peptidase M48B family
CFI11_RS18965	COG2204	response regulator
CFI11_RS19005	COG1295	ribonuclease BN
CFI11_RS19090	COG4638	Rieske (2fe-2S)
CFI11_RS19100	COG4176	ABC-type proline glycine betaine transport system permease component
CFI11_RS19105	COG4175	Glycine betaine
CFI11_RS19115	COG1309	transcriptional regulator
CFI11_RS19125	COG4974	Belongs to the 'phage' integrase family
CFI11_RS19135	COG0717	Belongs to the dCTP deaminase family
CFI11_RS19225	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS19235	COG0583	DNA-binding transcription factor activity
CFI11_RS19255	COG2814	Major facilitator Superfamily
CFI11_RS19270	COG0477	Major facilitator Superfamily
CFI11_RS19275	COG1959	2 iron, 2 sulfur cluster binding
CFI11_RS19300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_RS19315	COG0633	Ferredoxin
CFI11_RS19350	COG0737	Belongs to the 5'-nucleotidase family
CFI11_RS19395	COG0534	Mate efflux family protein
CFI11_RS19400	COG0569	domain protein
CFI11_RS19405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFI11_RS19410	COG0668	transmembrane transport
CFI11_RS19445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFI11_RS19470	COG4789	Type iii secretion
CFI11_RS19510	COG1450	Type ii and iii secretion system protein
CFI11_RS19515	COG4792	protein secretion
CFI11_RS19525	COG4794	Type iii secretion
CFI11_RS19530	COG4790	Type iii secretion
CFI11_RS19545	COG1157	protein secretion by the type III secretion system
CFI11_RS19580	COG0745	RESPONSE REGULATOR receiver
CFI11_RS19585	COG2205	protein histidine kinase activity
CFI11_RS19590	COG1917	Cupin 2, conserved barrel domain protein
CFI11_RS19590	COG2169	Transcriptional regulator
CFI11_RS19600	COG2814	Major facilitator Superfamily
CFI11_RS19610	COG0583	DNA-binding transcription factor activity
CFI11_RS19650	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CFI11_RS19655	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CFI11_RS19660	COG0714	Associated with various cellular activities
CFI11_RS19665	COG3831	ATPase activity
CFI11_RS19690	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CFI11_RS19695	COG0028	Belongs to the TPP enzyme family
CFI11_RS19700	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS19710	COG2267	carboxylic ester hydrolase activity
CFI11_RS19725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFI11_RS19750	COG1414	Transcriptional regulator
CFI11_RS19775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFI11_RS19780	COG0318	PFAM AMP-dependent synthetase and ligase
CFI11_RS19800	COG4585	Histidine kinase
CFI11_RS19805	COG2197	response regulator
CFI11_RS19825	COG0642	Histidine kinase
CFI11_RS19830	COG0745	RESPONSE REGULATOR receiver
CFI11_RS19860	COG4264	IucA IucC family
CFI11_RS19880	COG0251	oxidation-reduction process
CFI11_RS19910	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_RS19930	COG2133	pyrroloquinoline quinone binding
CFI11_RS19935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_RS19940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFI11_RS19945	COG4172	Belongs to the ABC transporter superfamily
CFI11_RS19950	COG4239	(ABC) transporter, permease
CFI11_RS19955	COG4174	ABC transporter (Permease)
CFI11_RS19960	COG4166	transmembrane transport
CFI11_RS19965	COG3474	cytochrome
CFI11_RS19980	COG2816	NAD+ diphosphatase activity
CFI11_RS19985	COG0737	Belongs to the 5'-nucleotidase family
CFI11_RS20005	COG1309	transcriptional regulator
CFI11_RS20025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFI11_RS20035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFI11_RS20045	COG1335	isochorismatase
CFI11_RS20050	COG0583	DNA-binding transcription factor activity
CFI11_RS20085	COG1063	alcohol dehydrogenase
CFI11_RS20100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFI11_RS20105	COG0154	amidase activity
CFI11_RS20110	COG2207	Transcriptional regulator
CFI11_RS20120	COG1522	sequence-specific DNA binding
CFI11_RS20125	COG0686	Belongs to the AlaDH PNT family
CFI11_RS20130	COG1970	mechanosensitive ion channel activity
CFI11_RS20135	COG0625	glutathione transferase activity
CFI11_RS20145	COG0072	phenylalanine-tRNA ligase activity
CFI11_RS20145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFI11_RS20165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFI11_RS20195	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFI11_RS20200	COG0746	molybdenum cofactor guanylyltransferase activity
CFI11_RS20240	COG1960	acyl-CoA dehydrogenase activity
CFI11_RS20245	COG0009	L-threonylcarbamoyladenylate synthase
CFI11_RS20250	COG1678	Uncharacterized ACR, COG1678
CFI11_RS20275	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFI11_RS20280	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS20285	COG1573	uracil-dna glycosylase
CFI11_RS20290	COG0540	Belongs to the ATCase OTCase family
CFI11_RS20310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFI11_RS20315	COG1505	serine-type exopeptidase activity
CFI11_RS20350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFI11_RS20370	COG0314	molybdopterin synthase activity
CFI11_RS20380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFI11_RS20385	COG0322	excinuclease ABC activity
CFI11_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS20400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_RS20400	COG0616	signal peptide processing
CFI11_RS20405	COG0842	Transport permease protein
CFI11_RS20410	COG1131	(ABC) transporter
CFI11_RS20415	COG0697	spore germination
CFI11_RS20420	COG1024	Enoyl-CoA hydratase
CFI11_RS20435	COG4977	sequence-specific DNA binding
CFI11_RS20435	COG1917	Cupin 2, conserved barrel domain protein
CFI11_RS20450	COG0339	signal peptide processing
CFI11_RS20455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CFI11_RS20460	COG0756	dUTP diphosphatase activity
CFI11_RS20465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFI11_RS20495	COG0606	chelatase, subunit chli
CFI11_RS20510	COG0792	nuclease activity
CFI11_RS20515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFI11_RS20525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFI11_RS20540	COG0180	Tryptophanyl-tRNA synthetase
CFI11_RS20570	COG0018	arginyl-trna synthetase
CFI11_RS20575	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFI11_RS20590	COG1744	ABC transporter substrate-binding protein PnrA-like
CFI11_RS20595	COG3845	ABC transporter
CFI11_RS20600	COG4603	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS20605	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFI11_RS20610	COG0730	response to heat
CFI11_RS20620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFI11_RS20640	COG0604	alcohol dehydrogenase
CFI11_RS20650	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFI11_RS20650	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CFI11_RS20660	COG0813	purine-nucleoside phosphorylase activity
CFI11_RS20715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFI11_RS20715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS20725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS20730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFI11_RS20735	COG0277	FAD linked oxidase domain protein
CFI11_RS20735	COG0247	lactate metabolic process
CFI11_RS20740	COG1802	Transcriptional regulator
CFI11_RS20790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFI11_RS20795	COG1120	ATPase activity
CFI11_RS20800	COG1309	transcriptional regulator
CFI11_RS20805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFI11_RS20815	COG0625	glutathione transferase activity
CFI11_RS20845	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_RS20850	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CFI11_RS20870	COG2211	Major facilitator Superfamily
CFI11_RS20880	COG1024	Enoyl-CoA hydratase
CFI11_RS20890	COG2080	2 iron, 2 sulfur cluster binding
CFI11_RS20925	COG0747	negative chemotaxis
CFI11_RS20945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS20975	COG1595	DNA-templated transcription, initiation
CFI11_RS21010	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFI11_RS21015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFI11_RS21020	COG0069	glutamate synthase activity
CFI11_RS21030	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_RS21035	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CFI11_RS21055	COG0284	orotidine-5'-phosphate decarboxylase activity
CFI11_RS21080	COG4191	Histidine kinase
CFI11_RS21085	COG0745	RESPONSE REGULATOR receiver
CFI11_RS21100	COG3383	formate dehydrogenase (NAD+) activity
CFI11_RS21110	COG0625	glutathione transferase activity
CFI11_RS21125	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS21150	COG1595	DNA-templated transcription, initiation
CFI11_RS21155	COG3806	Anti-sigma factor
CFI11_RS21185	COG1294	oxidase, subunit
CFI11_RS21190	COG1271	oxidase subunit
CFI11_RS21200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_RS21210	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFI11_RS21215	COG3257	ureidoglycine aminohydrolase activity
CFI11_RS21225	COG2351	hydroxyisourate hydrolase activity
CFI11_RS21230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFI11_RS21235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFI11_RS21235	COG1321	iron dependent repressor
CFI11_RS21240	COG1121	(ABC) transporter
CFI11_RS21245	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFI11_RS21250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFI11_RS21255	COG1012	belongs to the aldehyde dehydrogenase family
CFI11_RS21265	COG0612	Peptidase, M16
CFI11_RS21270	COG0612	Peptidase, M16
CFI11_RS21280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFI11_RS21295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFI11_RS21295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFI11_RS21310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFI11_RS21315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFI11_RS21320	COG3698	Phosphodiester glycosidase
CFI11_RS21325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFI11_RS21340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFI11_RS21350	COG1185	polyribonucleotide nucleotidyltransferase activity
CFI11_RS21360	COG0450	alkyl hydroperoxide reductase
CFI11_RS21375	COG0564	pseudouridine synthase activity
CFI11_RS21405	COG1280	lysine exporter protein (LysE YggA)
CFI11_RS21425	COG1366	Belongs to the anti-sigma-factor antagonist family
CFI11_RS21430	COG1366	Belongs to the anti-sigma-factor antagonist family
CFI11_RS21430	COG2208	phosphoserine phosphatase activity
CFI11_RS21430	COG2172	sigma factor antagonist activity
CFI11_RS21435	COG0405	Gamma-glutamyltransferase
CFI11_RS21460	COG1674	ftsk spoiiie
CFI11_RS21465	COG0436	Aminotransferase
CFI11_RS21470	COG0154	amidase activity
CFI11_RS21475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFI11_RS21480	COG2835	tetraacyldisaccharide 4'-kinase activity
CFI11_RS21495	COG0708	Exodeoxyribonuclease III
CFI11_RS21510	COG0745	RESPONSE REGULATOR receiver
CFI11_RS21530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFI11_RS21550	COG0495	leucyl-tRNA aminoacylation
CFI11_RS21565	COG0625	glutathione transferase activity
CFI11_RS21570	COG2081	HI0933 family
CFI11_RS21595	COG0312	modulator of DNA gyrase
CFI11_RS21615	COG1663	tetraacyldisaccharide 4'-kinase activity
CFI11_RS21625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFI11_RS21625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFI11_RS21635	COG1194	a g-specific adenine glycosylase
CFI11_RS21675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFI11_RS21690	COG3046	protein related to deoxyribodipyrimidine photolyase
CFI11_RS21705	COG0583	DNA-binding transcription factor activity
CFI11_RS21840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFI11_RS21850	COG1609	Transcriptional regulator
CFI11_RS21855	COG3214	Protein conserved in bacteria
CFI11_RS21865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFI11_RS21900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFI11_RS21920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS21975	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS22005	COG2226	methyltransferase
CFI11_RS22020	COG3842	ATPase activity
CFI11_RS22030	COG1175	transmembrane transport
CFI11_RS22035	COG0395	ABC-type sugar transport system, permease component
CFI11_RS22050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFI11_RS22055	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS22060	COG1609	Transcriptional regulator
CFI11_RS22090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFI11_RS22100	COG2358	TRAP transporter, solute receptor (TAXI family
CFI11_RS22120	COG3976	FMN-binding domain protein
CFI11_RS22120	COG1053	succinate dehydrogenase
CFI11_RS22170	COG0028	Belongs to the TPP enzyme family
CFI11_RS22190	COG3220	belongs to the UPF0276 family
CFI11_RS22225	COG1022	Amp-dependent synthetase and ligase
CFI11_RS22225	COG3320	Male sterility
CFI11_RS22235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CFI11_RS22245	COG0028	Belongs to the TPP enzyme family
CFI11_RS22290	COG0747	negative chemotaxis
CFI11_RS22300	COG0601	transmembrane transport
CFI11_RS22305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS22310	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS22315	COG4608	Belongs to the ABC transporter superfamily
CFI11_RS22320	COG4166	transmembrane transport
CFI11_RS22325	COG0601	transmembrane transport
CFI11_RS22330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS22330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS22335	COG4172	Belongs to the ABC transporter superfamily
CFI11_RS22340	COG1129	ABC transporter
CFI11_RS22365	COG0583	DNA-binding transcription factor activity
CFI11_RS22375	COG0489	protein tyrosine kinase activity
CFI11_RS22380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFI11_RS22385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFI11_RS22390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_RS22395	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFI11_RS22425	COG3119	arylsulfatase activity
CFI11_RS22435	COG2358	TRAP transporter, solute receptor (TAXI family
CFI11_RS22440	COG0583	DNA-binding transcription factor activity
CFI11_RS22465	COG5002	protein histidine kinase activity
CFI11_RS22470	COG1858	cytochrome C peroxidase
CFI11_RS22480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFI11_RS22485	COG0583	DNA-binding transcription factor activity
CFI11_RS22575	COG0515	serine threonine protein kinase
CFI11_RS22575	COG2815	serine threonine protein kinase
CFI11_RS22590	COG0628	permease
CFI11_RS22635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFI11_RS22640	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFI11_RS22655	COG2264	protein methyltransferase activity
CFI11_RS22670	COG0438	transferase activity, transferring glycosyl groups
CFI11_RS22685	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS22690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS22705	COG1802	Transcriptional regulator
CFI11_RS22715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFI11_RS22720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFI11_RS22725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFI11_RS22745	COG0625	glutathione transferase activity
CFI11_RS22750	COG2808	Putative FMN-binding domain
CFI11_RS22760	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFI11_RS22770	COG4143	(ABC) transporter
CFI11_RS22775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFI11_RS22780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFI11_RS22805	COG2171	N-acyltransferase activity
CFI11_RS22825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFI11_RS22830	COG0557	exoribonuclease II activity
CFI11_RS22850	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CFI11_RS22885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFI11_RS22895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFI11_RS22925	COG1968	undecaprenyl-diphosphatase activity
CFI11_RS22950	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFI11_RS22955	COG0517	IMP dehydrogenase activity
CFI11_RS22955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFI11_RS22970	COG1137	ATPase activity
CFI11_RS22975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFI11_RS22980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFI11_RS23005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFI11_RS23020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFI11_RS23025	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFI11_RS23050	COG0443	Heat shock 70 kDa protein
CFI11_RS23055	COG0484	heat shock protein binding
CFI11_RS23065	COG2003	Belongs to the UPF0758 family
CFI11_RS23070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFI11_RS23080	COG0653	protein targeting
CFI11_RS23085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFI11_RS23090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFI11_RS23095	COG0494	nUDIX hydrolase
CFI11_RS23100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFI11_RS23115	COG0779	Required for maturation of 30S ribosomal subunits
CFI11_RS23130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFI11_RS23140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFI11_RS23145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFI11_RS23155	COG2226	methyltransferase
CFI11_RS23180	COG3034	peptidoglycan biosynthetic process
CFI11_RS23190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFI11_RS23195	COG1132	(ABC) transporter
CFI11_RS23200	COG1132	(ABC) transporter
CFI11_RS23210	COG0494	nUDIX hydrolase
CFI11_RS23220	COG0494	nUDIX hydrolase
CFI11_RS23225	COG0745	RESPONSE REGULATOR receiver
CFI11_RS23240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFI11_RS23250	COG0137	argininosuccinate synthase activity
CFI11_RS23270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFI11_RS23275	COG1105	Belongs to the carbohydrate kinase PfkB family
CFI11_RS23280	COG0280	phosphate acetyltransferase
CFI11_RS23280	COG0281	malic enzyme
CFI11_RS23285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFI11_RS23290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFI11_RS23295	COG1420	regulation of RNA biosynthetic process
CFI11_RS23300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFI11_RS23305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFI11_RS23310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFI11_RS23325	COG0357	Ribosomal RNA small subunit methyltransferase G
CFI11_RS23330	COG0445	tRNA wobble uridine modification
CFI11_RS23335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFI11_RS23340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFI11_RS23345	COG1981	membrane
CFI11_RS23355	COG1475	DNA binding
CFI11_RS23365	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CFI11_RS23370	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CFI11_RS23380	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_RS23385	COG1562	ergosterol biosynthetic process
CFI11_RS23390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CFI11_RS23395	COG5621	secreted hydrolase
CFI11_RS23400	COG1233	COG1233 Phytoene dehydrogenase and related
CFI11_RS23405	COG0142	geranyltranstransferase activity
CFI11_RS23410	COG0500	methyltransferase
CFI11_RS23415	COG1063	alcohol dehydrogenase
CFI11_RS23420	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CFI11_RS23425	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_RS23430	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_RS23465	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFI11_RS23470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFI11_RS23475	COG3191	aminopeptidase activity
CFI11_RS23480	COG0662	Cupin 2, conserved barrel domain protein
CFI11_RS23505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS23515	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFI11_RS23520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFI11_RS23525	COG1230	cation diffusion facilitator family transporter
CFI11_RS23535	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFI11_RS23540	COG2211	Major facilitator Superfamily
CFI11_RS23545	COG0644	oxidoreductase
CFI11_RS23550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CFI11_RS23560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_RS23590	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFI11_RS23605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFI11_RS23615	COG3842	ATPase activity
CFI11_RS23630	COG0395	ABC-type sugar transport system, permease component
CFI11_RS23650	COG1063	alcohol dehydrogenase
CFI11_RS23655	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS23660	COG2084	Dehydrogenase
CFI11_RS23670	COG0402	S-adenosylhomocysteine deaminase activity
CFI11_RS23675	COG2188	Transcriptional regulator
CFI11_RS23680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFI11_RS23685	COG0747	negative chemotaxis
CFI11_RS23710	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_RS23715	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CFI11_RS23720	COG1429	ligase activity, forming nitrogen-metal bonds
CFI11_RS23725	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CFI11_RS23760	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CFI11_RS23770	COG0156	8-amino-7-oxononanoate synthase activity
CFI11_RS23775	COG3474	cytochrome
CFI11_RS23780	COG0457	Tetratricopeptide repeat
CFI11_RS23785	COG1487	ribonuclease activity
CFI11_RS23810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CFI11_RS23815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_RS23825	COG1216	Glycosyl transferase, family 2
CFI11_RS23840	COG1216	Glycosyl transferase, family 2
CFI11_RS23905	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFI11_RS24010	COG1192	Involved in chromosome partitioning
CFI11_RS24015	COG1192	Involved in chromosome partitioning
CFI11_RS24030	COG4948	Mandelate Racemase Muconate Lactonizing
CFI11_RS24035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFI11_RS24050	COG1609	Transcriptional regulator
CFI11_RS24055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFI11_RS24060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFI11_RS24070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFI11_RS24070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFI11_RS24075	COG3395	kinase activity
CFI11_RS24080	COG0235	Class ii aldolase
CFI11_RS24085	COG3622	Belongs to the hyi family
CFI11_RS24100	COG0747	negative chemotaxis
CFI11_RS24105	COG0601	transmembrane transport
CFI11_RS24110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFI11_RS24115	COG0444	Belongs to the ABC transporter superfamily
CFI11_RS24120	COG4608	Belongs to the ABC transporter superfamily
CFI11_RS24135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFI11_RS24140	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFI11_RS24145	COG0129	dihydroxy-acid dehydratase activity
CFI11_RS24150	COG1028	Short-chain dehydrogenase reductase Sdr
CFI11_RS24160	COG1802	Transcriptional regulator
CFI11_RS24180	COG2721	sulfolactate sulfo-lyase activity
CFI11_RS24185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFI11_RS24195	COG0697	spore germination
CFI11_RS24200	COG0246	Mannitol dehydrogenase
CFI11_RS24205	COG1904	glucuronate isomerase
CFI11_RS24220	COG0673	inositol 2-dehydrogenase activity
CFI11_RS24225	COG1312	Catalyzes the dehydration of D-mannonate