locus-tag class description DY252_RS00025 ENOG4108JQC penicillin-binding protein 1A DY252_RS00030 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase DY252_RS00040 ENOG4105CPQ Dehydrogenase DY252_RS00045 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS00055 ENOG4105GQU Trap dicarboxylate transporter, dctp subunit DY252_RS00060 ENOG4107XBN GntR Family Transcriptional Regulator DY252_RS00070 ENOG4105DEI Mannitol dehydrogenase DY252_RS00075 ENOG4107SS6 2-dehydro-3-deoxygluconokinase DY252_RS00125 ENOG4105G47 Methyltransferase, type 11 DY252_RS00130 ENOG4107RGC Glycosyl transferase, family 2 DY252_RS00145 ENOG4108JJ6 Type I secretion system ATPase DY252_RS00155 ENOG4105E2K Glycosyl transferase (Group 1 DY252_RS00160 ENOG4105EUF amidase EC 3.5.1.4 DY252_RS00165 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase DY252_RS00170 ENOG4108JQ6 ABC transporter DY252_RS00175 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS00180 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS00190 ENOG4105MP9 class II Aldolase DY252_RS00205 ENOG4105C8Y Acetylornithine aminotransferase DY252_RS00210 ENOG4107S5T Carbohydrate kinase DY252_RS00215 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) DY252_RS00230 ENOG4105C2J ABC transporter DY252_RS00235 ENOG4105D4B ABC, transporter DY252_RS00240 ENOG4105E98 transcriptional regulator DeoR family DY252_RS00250 ENOG4105C9F isomerase DY252_RS00295 ENOG4105W1Y Transcriptional regulator DY252_RS00305 ENOG4107ZQN disulfide bond DY252_RS00315 ENOG41080T7 secreted protein DY252_RS00325 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) DY252_RS00355 ENOG4105KST dependent repressor DY252_RS00375 ENOG4107QX9 Thiol disulfide interChange protein DY252_RS00380 ENOG4107ZT5 Thiol disulfide interchange protein DY252_RS00410 ENOG4107QIV Cytochrome c biogenesis protein DY252_RS00435 ENOG4105W1Y Transcriptional regulator DY252_RS00460 ENOG4107QN2 dihydrolipoyl dehydrogenase DY252_RS00485 ENOG4108C33 Resolvase DY252_RS00505 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DY252_RS00540 ENOG4105CVJ phosphoglycerate mutase DY252_RS00545 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS00550 ENOG4108I5D sulfate abc transporter DY252_RS00560 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS00570 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC DY252_RS00580 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) DY252_RS00590 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) DY252_RS00595 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) DY252_RS00600 ENOG4105E39 Enoyl-CoA hydratase DY252_RS00605 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) DY252_RS00610 ENOG4105EJ9 Membrane DY252_RS00615 ENOG4105F27 Major Facilitator DY252_RS00620 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) DY252_RS00630 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DY252_RS00635 ENOG4105D07 Signal peptide peptidase, SppA DY252_RS00640 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DY252_RS00645 ENOG4105CAT Cytidine monophosphate kinase DY252_RS00670 ENOG4105CHM Aminotransferase DY252_RS00680 ENOG4105C5I Dehydrogenase DY252_RS00685 ENOG4105MP9 class II Aldolase DY252_RS00700 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DY252_RS00715 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DY252_RS00720 ENOG4105F8J Adenylate Guanylate cyclase DY252_RS00735 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DY252_RS00740 ENOG4107SDU Methyl-accepting chemotaxis DY252_RS00745 ENOG4107SDU Methyl-accepting chemotaxis DY252_RS00750 ENOG4108ZZ3 UPF0260 protein DY252_RS00775 ENOG4105EE8 May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity) DY252_RS00785 ENOG4105C1B dTDP-glucose 4-6-dehydratase DY252_RS00815 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) DY252_RS00855 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DY252_RS00860 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) DY252_RS00865 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) DY252_RS00875 ENOG4108IAJ Nad-dependent epimerase dehydratase DY252_RS00880 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) DY252_RS00885 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) DY252_RS00895 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) DY252_RS00910 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase DY252_RS00915 ENOG4105DVK Precorrin-2 c20-methyltransferase DY252_RS00925 ENOG4105CIA precorrin-4 C(11)-methyltransferase DY252_RS00995 ENOG4105EHG Permease protein DY252_RS01000 ENOG4105E0A ABC, transporter DY252_RS01005 ENOG4105CPD ethanolamine ammonia-lyase DY252_RS01010 ENOG4107FQ9 ethanolamine ammonia-lyase DY252_RS01020 ENOG4108RAC Rubrerythrin DY252_RS01035 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) DY252_RS01040 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) DY252_RS01045 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DY252_RS01050 ENOG4107ZGG Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) DY252_RS01055 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) DY252_RS01060 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination DY252_RS01070 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) DY252_RS01075 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) DY252_RS01080 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP DY252_RS01085 ENOG4108WRK Transcriptional regulator DY252_RS01090 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) DY252_RS01095 ENOG4107RCQ (CBS) domain DY252_RS01100 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) DY252_RS01105 ENOG4105C9A Phoh family DY252_RS01110 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DY252_RS01125 ENOG41090R7 Ferric uptake DY252_RS01140 ENOG41072GX Peptidase M22 Glycoprotease DY252_RS01145 ENOG4108UQS dipeptidase DY252_RS01165 ENOG4108JP0 extracellular solute-binding protein family 1 DY252_RS01175 ENOG4105FKQ transcriptional regulator DY252_RS01180 ENOG4108302 MgtC SapB transporter DY252_RS01190 ENOG4105N14 lysine exporter protein LysE YggA DY252_RS01200 ENOG4105D06 uba thif-type nad fad binding protein DY252_RS01205 ENOG4105C6T cysteine synthase DY252_RS01210 ENOG410847I Transcriptional regulator, BadM Rrf2 family DY252_RS01215 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) DY252_RS01235 ENOG4105BZU Histidine kinase DY252_RS01240 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) DY252_RS01245 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) DY252_RS01250 ENOG4105CPN adenine deaminase DY252_RS01255 ENOG4108T5G Adenylate DY252_RS01260 ENOG4105ECC imidazole-glycerol-phosphate dehydratase DY252_RS01275 ENOG4108154 Acetyltransferase (GNAT) family DY252_RS01280 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase DY252_RS01285 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) DY252_RS01295 ENOG4105K59 histidine triad (HIT) protein DY252_RS01315 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase DY252_RS01325 ENOG4105CBN LysR family transcriptional regulator DY252_RS01330 ENOG4105CHR reductase DY252_RS01355 ENOG4105CPC Aldo Keto reductase DY252_RS01365 ENOG410642W LysR family Transcriptional regulator DY252_RS01370 ENOG4105C0P Mg chelatase subunit ChlI DY252_RS01390 ENOG4108SY4 MarR family Transcriptional regulator DY252_RS01410 ENOG4108U78 Glutathione S-transferase DY252_RS01420 ENOG4105K8K Cupin 2, conserved barrel DY252_RS01455 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs DY252_RS01475 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 DY252_RS01480 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) DY252_RS01485 ENOG4108YXA Membrane DY252_RS01495 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) DY252_RS01500 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) DY252_RS01505 ENOG4108UHJ MAF-like protein DY252_RS01510 ENOG4105E2X shikimate dehydrogenase DY252_RS01515 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DY252_RS01555 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DY252_RS01565 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DY252_RS01580 ENOG4105C7Z Conserved Protein DY252_RS01590 ENOG4105NZG Ferredoxin DY252_RS01595 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) DY252_RS01600 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) DY252_RS01605 ENOG4107YTN Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity) DY252_RS01640 ENOG4108Z9W Outer membrane porin DY252_RS01655 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DY252_RS01665 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DY252_RS01670 ENOG4107QJN gtp cyclohydrolase ii DY252_RS01690 ENOG4105C31 Tryptophanyl-tRNA synthetase DY252_RS01700 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) DY252_RS01705 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) DY252_RS01715 ENOG4105C6K Malic enzyme DY252_RS01720 ENOG4107JPU DY252_RS01730 ENOG4108UR8 BAX protein DY252_RS01735 ENOG41083MR nifu domain-containing protein DY252_RS01750 ENOG4108UVJ appr-1-p processing domain protein DY252_RS01755 ENOG4105F0N pyrophosphate phospho-hydrolase DY252_RS01760 ENOG4107R51 Glycosyl transferase, family 2 DY252_RS01765 ENOG4105CMR udp-glucose 4-epimerase DY252_RS01770 ENOG4108MGI Transcriptional regulator DY252_RS01795 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DY252_RS01800 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ DY252_RS01805 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) DY252_RS01810 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) DY252_RS01815 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) DY252_RS01820 ENOG4105CSA Coproporphyrinogen iii oxidase DY252_RS01840 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein DY252_RS01855 ENOG4105C2X Arabinose 5-phosphate isomerase DY252_RS01870 ENOG4108IUZ ABC transporter DY252_RS01875 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DY252_RS01880 ENOG4107TNS sigma 54 modulation protein ribosomal protein S30ea DY252_RS01885 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN DY252_RS01890 ENOG4105EYM Major Facilitator superfamily DY252_RS01895 ENOG4105CI3 gtp-binding protein typa DY252_RS01925 ENOG41082FP UPF0102 protein DY252_RS01930 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) DY252_RS01940 ENOG4105CSM endonuclease III DY252_RS01950 ENOG4105CFG Acts as a chaperone (By similarity) DY252_RS01955 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) DY252_RS01960 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) DY252_RS01965 ENOG4105C2M dna polymerase I DY252_RS01985 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DY252_RS01995 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) DY252_RS02000 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DY252_RS02010 ENOG4105DA5 (ABC) transporter DY252_RS02020 ENOG4105E8V Alpha Beta Hydrolase Fold protein DY252_RS02040 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DY252_RS02045 ENOG4105C7K acetolactate synthase DY252_RS02060 ENOG4105D3Q Sugar transferase DY252_RS02080 ENOG4105BZU Histidine kinase DY252_RS02085 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS02090 ENOG4108ZXC Two component transcriptional regulator, luxr family DY252_RS02105 ENOG4105CBN LysR family transcriptional regulator DY252_RS02130 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS02150 ENOG410633P Hydantoin racemase DY252_RS02155 ENOG4105EMF GntR family transcriptional regulator DY252_RS02160 ENOG4105HF0 Membrane DY252_RS02180 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DY252_RS02210 ENOG4105CHR reductase DY252_RS02215 ENOG4105CGU Enoyl-CoA hydratase DY252_RS02225 ENOG4105CSU acyl-Coa dehydrogenase DY252_RS02245 ENOG4105CEY Amp-dependent synthetase and ligase DY252_RS02265 ENOG4105MQ2 17 kDa surface antigen DY252_RS02275 ENOG4105DYB Isoaspartyl dipeptidase DY252_RS02285 ENOG4105DJ2 Major Facilitator Superfamily DY252_RS02295 ENOG4107ENK receptor DY252_RS02300 ENOG4106QJH hemin transport protein DY252_RS02305 ENOG4107R4I Periplasmic binding protein DY252_RS02310 ENOG4105EHG Permease protein DY252_RS02315 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) DY252_RS02320 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS02330 ENOG4108JPW Aminotransferase DY252_RS02335 ENOG4105C26 Dehydrogenase DY252_RS02340 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DY252_RS02350 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DY252_RS02360 ENOG4105BZM domain protein DY252_RS02370 ENOG4105DJV ribulose-phosphate 3-epimerase DY252_RS02380 ENOG4105ESV Glycosyl transferase, family 4 DY252_RS02390 ENOG4105E32 cytoplasmic protein DY252_RS02395 ENOG4105DC1 bifunctional purine biosynthesis protein purh DY252_RS02415 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DY252_RS02420 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DY252_RS02425 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase DY252_RS02430 ENOG4105K9H YciI-like protein DY252_RS02450 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) DY252_RS02460 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) DY252_RS02465 ENOG4108KXV response regulator DY252_RS02470 ENOG4105RK9 auxin efflux carrier DY252_RS02475 ENOG41082BR 50S ribosomal protein L35 DY252_RS02480 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DY252_RS02485 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) DY252_RS02490 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) DY252_RS02500 ENOG4105BZU Histidine kinase DY252_RS02515 ENOG41090KN UPF0303 protein DY252_RS02525 ENOG4105CAY ferredoxin--nadp reductase DY252_RS02530 ENOG4105K8N protein family UPF0079, ATPase DY252_RS02540 ENOG4108S0S Nucleotidyl transferase DY252_RS02550 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation DY252_RS02555 ENOG4105K63 Thioredoxin DY252_RS02560 ENOG4105C8Q Methyl-accepting chemotaxis DY252_RS02585 ENOG4108YZA Nitrogen regulatory protein pii DY252_RS02605 ENOG4105W49 UPF0434 protein DY252_RS02615 ENOG4105K63 Thioredoxin DY252_RS02640 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH DY252_RS02645 ENOG4105C7I Dehydrogenase DY252_RS02650 ENOG4108IG5 Transcriptional regulator DY252_RS02655 ENOG4105C1P efflux transporter, rnd family, mfp subunit DY252_RS02675 ENOG4105D0M Protease HtpX homolog DY252_RS02685 ENOG4105HFZ Membrane DY252_RS02700 ENOG4105CV6 ABC transporter, permease DY252_RS02705 ENOG4108I0Y (ABC) transporter DY252_RS02710 ENOG4108UJV acyl-CoA thioesterase i DY252_RS02725 ENOG4105CPC Aldo Keto reductase DY252_RS02730 ENOG4105EUB pirin domain protein DY252_RS02750 ENOG4108KTG Membrane protein, drug metabolite transporter DY252_RS02755 ENOG4108ZT1 Transcriptional regulator DY252_RS02810 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein DY252_RS02835 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component DY252_RS02840 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component DY252_RS02845 ENOG4108JQ5 ABC transporter DY252_RS02865 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DY252_RS02875 ENOG4108RG0 uracil-dna glycosylase DY252_RS02880 ENOG4105KZX Pterin carbinolamine dehydratase DY252_RS02890 ENOG4108SXK Transporter Drug Metabolite Exporter family DY252_RS02895 ENOG4105DFI Membrane DY252_RS02900 ENOG4108SXK Transporter Drug Metabolite Exporter family DY252_RS02910 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) DY252_RS02925 ENOG410829K Lysine exporter protein (Lyse ygga) DY252_RS02945 ENOG4105G9V cytochrome C DY252_RS02950 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) DY252_RS02965 ENOG4105C1J atp-dependent rna helicase DY252_RS02980 ENOG4105C1G acyl-Coa dehydrogenase DY252_RS02985 ENOG4105CHU acetyl-coa acetyltransferase DY252_RS03005 ENOG4105C1G acyl-Coa dehydrogenase DY252_RS03010 ENOG4105CAF HipA N-terminal domain protein DY252_RS03020 ENOG4105E51 psp operon transcriptional activator DY252_RS03025 ENOG41087YS Phage shock protein A DY252_RS03060 ENOG4105CI0 Citrate lyase DY252_RS03065 ENOG4105DJG MaoC domain protein dehydratase DY252_RS03070 ENOG410612Q succinate dehydrogenase (cytochrome b-556 subunit) DY252_RS03080 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) DY252_RS03100 ENOG4105DHG Allantoate amidinohydrolase DY252_RS03115 ENOG4105VT2 5-hydroxyisourate hydrolase DY252_RS03125 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding DY252_RS03135 ENOG4107Y2X deaminase DY252_RS03140 ENOG4105C2J ABC transporter DY252_RS03180 ENOG41067B5 Histone deacetylase superfamily protein DY252_RS03185 ENOG4105EJC lysr family transcriptional regulator DY252_RS03195 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DY252_RS03205 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein DY252_RS03210 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS03220 ENOG4105C0Z ABC transporter DY252_RS03225 ENOG4108IV0 ABC, transporter DY252_RS03230 ENOG4108M9X Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) DY252_RS03235 ENOG4108YZ9 Urea amidohydrolase subunit gamma DY252_RS03240 ENOG4105KI2 Urea amidohydrolase subunit beta DY252_RS03245 ENOG4105CQM Urea amidohydrolase subunit alpha DY252_RS03250 ENOG4105MMR Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity) DY252_RS03255 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) DY252_RS03260 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) DY252_RS03270 ENOG4105NPE arsR family transcriptional regulator DY252_RS03275 ENOG4107ZYJ bioY protein DY252_RS03280 ENOG4108JJB ABC transporter DY252_RS03285 ENOG4107QCX Transporter DY252_RS03300 ENOG4105CC0 LysR family Transcriptional regulator DY252_RS03310 ENOG4105DTD Dehydrogenase DY252_RS03340 ENOG4105DG4 malate L-lactate dehydrogenase DY252_RS03350 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein DY252_RS03360 ENOG4105D0M Protease HtpX homolog DY252_RS03365 ENOG4108JJ6 Type I secretion system ATPase DY252_RS03635 ENOG4107F2M hemolysin-type calcium-binding region DY252_RS03645 ENOG4105DJT lAO AO transport system ATPase DY252_RS03665 ENOG4105MIR Phenylalanine 4-monooxygenase DY252_RS03670 ENOG4108ZRZ Transcriptional regulator (AsnC family) DY252_RS03680 ENOG4105KK4 UPF0060 membrane protein DY252_RS03685 ENOG4105BZU Histidine kinase DY252_RS03690 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS03695 ENOG4105EQD regulatoR DY252_RS03700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS03715 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DY252_RS03720 ENOG4107TF3 peptidylprolyl cis-trans isomerase DY252_RS03740 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DY252_RS03770 ENOG4105CEV competence damage-inducible protein DY252_RS03785 ENOG4105E7Q Cob(II)yrinic acid a,c-diamide reductase DY252_RS03820 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) DY252_RS03865 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters DY252_RS03875 ENOG4108W63 CRP FNR family transcriptional regulator DY252_RS03890 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) DY252_RS03895 ENOG4105CQB FAD linked oxidase domain protein DY252_RS03900 ENOG4105EU8 FAD linked oxidase domain protein DY252_RS03905 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) DY252_RS03915 ENOG4105PWN phosphate abc transporter DY252_RS03920 ENOG4105C8U phosphate abc transporter DY252_RS03925 ENOG4105E2Z phosphate ABC transporter (Permease DY252_RS03930 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DY252_RS03940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DY252_RS03955 ENOG4105CHR reductase DY252_RS03960 ENOG4107ZVW dihydroneopterin aldolase DY252_RS03965 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) DY252_RS03970 ENOG4105C2W permease DY252_RS03975 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DY252_RS03980 ENOG4108ZAF Molybdopterin DY252_RS03995 ENOG4105DWV Homoserine O-trans-acetylase DY252_RS04000 ENOG4105DWV Homoserine O-trans-acetylase DY252_RS04010 ENOG4105CIH Imidazole acetol-phosphate transaminase DY252_RS04020 ENOG4108594 Permease of the drug metabolite transporter DY252_RS04035 ENOG4105E9Q Acyl-transferase DY252_RS04050 ENOG4105CAK Cell division ATP-binding protein ftsE DY252_RS04065 ENOG4108SF5 RNA Polymerase DY252_RS04070 ENOG4108S3W Anti-feci sigma factor, fecr DY252_RS04085 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) DY252_RS04090 ENOG4105CH7 arginosuccinase DY252_RS04095 ENOG4107ZT5 Thiol disulfide interchange protein DY252_RS04100 ENOG4108RVA ribokinase DY252_RS04105 ENOG4105CMG Carbohydrate kinase DY252_RS04110 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase DY252_RS04115 ENOG4105C10 Electron transfer flavoprotein DY252_RS04120 ENOG4105BZJ Electron transfer flavoprotein DY252_RS04125 ENOG4108WBT adenosyltransferase DY252_RS04135 ENOG4108JUA Transcriptional regulator DY252_RS04140 ENOG4105I5W Transporter DY252_RS04150 ENOG4105D7T ABC transporter DY252_RS04155 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) DY252_RS04160 ENOG4105CYM Glutathione S-transferase DY252_RS04180 ENOG4105C1G acyl-Coa dehydrogenase DY252_RS04195 ENOG4108IND Tetr family transcriptional regulator DY252_RS04200 ENOG4105F6U Short-chain dehydrogenase reductase Sdr DY252_RS04205 ENOG4105BZU Histidine kinase DY252_RS04210 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DY252_RS04215 ENOG4105CUV Homoserine Kinase DY252_RS04220 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) DY252_RS04230 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DY252_RS04235 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) DY252_RS04240 ENOG4108EYQ The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DY252_RS04245 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor DY252_RS04260 ENOG4105EHV domain protein DY252_RS04265 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) DY252_RS04270 ENOG4108UJU UPF0301 protein DY252_RS04290 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) DY252_RS04295 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) DY252_RS04300 ENOG4107QS1 Cytochrome C Oxidase, Subunit III DY252_RS04315 ENOG4105CTD carboxy-peptidase DY252_RS04320 ENOG4105IJJ transcriptional regulator, crp fnr family DY252_RS04330 ENOG4105C1V Peptidase, M16 DY252_RS04355 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) DY252_RS04365 ENOG4105CH2 amidohydrolase DY252_RS04380 ENOG4105C5Q Transcriptional regulator DY252_RS04385 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DY252_RS04390 ENOG4105C26 Dehydrogenase DY252_RS04395 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase DY252_RS04400 ENOG4108UN4 phage SPO1 DNA polymerase-related protein DY252_RS04405 ENOG4105E4C Lytic transglycosylase catalytic DY252_RS04420 ENOG4105KWW Biogenesis protein DY252_RS04425 ENOG4107QX9 Thiol disulfide interChange protein DY252_RS04430 ENOG4105DA4 cytochrome c-type biogenesis protein DY252_RS04435 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) DY252_RS04445 ENOG41060IM Heme exporter protein DY252_RS04450 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) DY252_RS04455 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) DY252_RS04465 ENOG4105C8J )-transporter DY252_RS04470 ENOG4105BZU Histidine kinase DY252_RS04475 ENOG4107QM5 aconitate hydratase DY252_RS04485 ENOG4105C0Z ABC transporter DY252_RS04495 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS04510 ENOG4108IV0 ABC, transporter DY252_RS04515 ENOG4105DZS Phenylacetate-CoA ligase DY252_RS04520 ENOG4108M4U conserved membrane protein DY252_RS04530 ENOG4105D65 subunit l DY252_RS04535 ENOG4108ZE9 Monovalent cation H antiporter subunit C DY252_RS04540 ENOG4107R4Z monovalent cation h antiporter subunit d DY252_RS04545 ENOG4105SC1 monovalent cation H antiporter subunit E DY252_RS04550 ENOG4105W4C monovalent cation H antiporter subunit F DY252_RS04555 ENOG4105KJM monovalent cation h antiporter subunit g DY252_RS04560 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) DY252_RS04570 ENOG4108YZN class I peptide chain release factor DY252_RS04575 ENOG4105WD1 Membrane DY252_RS04600 ENOG4105BZU Histidine kinase DY252_RS04620 ENOG4105ERG peptidase m48, ste24p DY252_RS04645 ENOG4105F1J Homogentisate 1,2-dioxygenase DY252_RS04660 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS04665 ENOG4105C1G acyl-Coa dehydrogenase DY252_RS04670 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DY252_RS04675 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS04680 ENOG4105F38 ABC transporter, permease DY252_RS04685 ENOG4105D38 putrescine abc transporter DY252_RS04690 ENOG4107RUE extracellular solute-binding protein family 1 DY252_RS04700 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) DY252_RS04710 ENOG4108WFR AraC Family Transcriptional Regulator DY252_RS04725 ENOG4105R1U AraC Family Transcriptional Regulator DY252_RS04735 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic DY252_RS04770 ENOG4105BZU Histidine kinase DY252_RS04775 ENOG41063SB peptidase DY252_RS04785 ENOG4107QNM Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) DY252_RS04790 ENOG4108Z7G MaoC domain protein dehydratase DY252_RS04795 ENOG4105DTN riboflavin biosynthesis protein ribF DY252_RS04805 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) DY252_RS04825 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) DY252_RS04840 ENOG4105ER2 Ompa motb domain protein DY252_RS04845 ENOG4105E14 MotA TolQ exbB proton channel DY252_RS04855 ENOG4105Q26 Siderophore-interacting protein DY252_RS04860 ENOG4107RPQ ABC transporter DY252_RS04865 ENOG4105CC5 ABC transporter DY252_RS04870 ENOG4105DIK (ABC) transporter DY252_RS04875 ENOG4105DSE periplasmic solute binding protein DY252_RS04880 ENOG4105KST dependent repressor DY252_RS04890 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DY252_RS04900 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) DY252_RS04905 ENOG4108REZ Imidazole glycerol phosphate synthase DY252_RS04910 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DY252_RS04930 ENOG4105CAQ asparagine synthetase DY252_RS04935 ENOG4107XU6 Glycosyl transferase (Group 1 DY252_RS04970 ENOG4105C5E polysaccharide biosynthesis protein DY252_RS04975 ENOG4105D2T synthase DY252_RS04980 ENOG4105BZ1 (ABC) transporter DY252_RS04990 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) DY252_RS04995 ENOG4105K46 50S ribosomal protein l27 DY252_RS05000 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control DY252_RS05005 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) DY252_RS05010 ENOG4108WRK Transcriptional regulator DY252_RS05050 ENOG4107R16 Multicopper oxidase DY252_RS05080 ENOG4107Z1W Fructose transport system kinase DY252_RS05085 ENOG4105C2J ABC transporter DY252_RS05090 ENOG4105CNN ABC, transporter DY252_RS05095 ENOG4107R5G Periplasmic binding protein LacI transcriptional regulator DY252_RS05105 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DY252_RS05120 ENOG4105EIX cytochrome c1 DY252_RS05125 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DY252_RS05130 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) DY252_RS05135 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DY252_RS05155 ENOG4105CYW agmatinase DY252_RS05165 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS05170 ENOG4105CBG Sulfatase DY252_RS05180 ENOG4107R7Y intracellular protease Pfpi family DY252_RS05195 ENOG41090HR transcriptional regulator DY252_RS05200 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DY252_RS05205 ENOG4105E0F Histidine kinase DY252_RS05215 ENOG4105DP0 ferredoxin-NADP reductase DY252_RS05220 ENOG4107SDU Methyl-accepting chemotaxis DY252_RS05225 ENOG4107SDU Methyl-accepting chemotaxis DY252_RS05230 ENOG4108Z7R Chaperone CsaA DY252_RS05245 ENOG4105II7 pyrroline-5-carboxylate reductase DY252_RS05260 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) DY252_RS05265 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) DY252_RS05275 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DY252_RS05285 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DY252_RS05290 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) DY252_RS05295 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) DY252_RS05300 ENOG4105C3G gtp-binding protein DY252_RS05305 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DY252_RS05310 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DY252_RS05315 ENOG4105CPQ Dehydrogenase DY252_RS05325 ENOG4105C5Q Transcriptional regulator DY252_RS05330 ENOG4105D3R alkyl hydroperoxide reductase DY252_RS05335 ENOG4108X7C Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) DY252_RS05360 ENOG4105E0F Histidine kinase DY252_RS05380 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DY252_RS05385 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) DY252_RS05390 ENOG4105C5Q Transcriptional regulator DY252_RS05395 ENOG4105CFM UPF0317 protein DY252_RS05410 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS05420 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DY252_RS05440 ENOG4105RD8 TRAP dicarboxylate transporter DY252_RS05450 ENOG4108T5G Adenylate DY252_RS05460 ENOG4105C3M thioredoxin reductase DY252_RS05465 ENOG4105F7P transcriptional regulator AsnC family DY252_RS05470 ENOG4105ERG peptidase m48, ste24p DY252_RS05485 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) DY252_RS05495 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DY252_RS05500 ENOG4105KTH gatB Yqey DY252_RS05505 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DY252_RS05510 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DY252_RS05585 ENOG4105XB7 anti-repressor protein DY252_RS05720 ENOG4105ED4 portal protein DY252_RS05775 ENOG4105CMG Carbohydrate kinase DY252_RS05780 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 DY252_RS05790 ENOG4105CPQ Dehydrogenase DY252_RS05805 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component DY252_RS05815 ENOG4105DKT Transcriptional regulator DY252_RS05820 ENOG4105CHR reductase DY252_RS05830 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DY252_RS05835 ENOG41077A9 carbonic anhydrase DY252_RS05840 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) DY252_RS05845 ENOG41076YT nitrate reductase, gamma subunit DY252_RS05850 ENOG4105R3A Nitrate reductase DY252_RS05855 ENOG4108IUE nitrate reductase beta subunit DY252_RS05860 ENOG4105CRU nitrate reductase, alpha subunit DY252_RS05865 ENOG4105DQQ Major facilitator superfamily MFS_1 DY252_RS05905 ENOG4105IJJ transcriptional regulator, crp fnr family DY252_RS05920 ENOG4108T0W nitrous oxide maturation protein NosY DY252_RS05925 ENOG4105CIG ABC transporter DY252_RS05935 ENOG4105EQJ Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity) DY252_RS05940 ENOG4105HEE Binding Domain protein DY252_RS05950 ENOG4105ETE Transcriptional regulator (LacI family DY252_RS05970 ENOG4108SV3 Tmao reductase system periplasmic protein tort DY252_RS05975 ENOG4105C2J ABC transporter DY252_RS05980 ENOG4105CNN ABC, transporter DY252_RS05985 ENOG4105C2J ABC transporter DY252_RS05990 ENOG4105CNN ABC, transporter DY252_RS06025 ENOG4105DS0 Transcriptional regulator, Crp Fnr family DY252_RS06060 ENOG41062B0 ABC transporter, permease DY252_RS06065 ENOG4105C2J ABC transporter DY252_RS06070 ENOG4105D7K pfkb domain protein DY252_RS06075 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) DY252_RS06085 ENOG4105DH8 myo-inositol catabolism DY252_RS06090 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) DY252_RS06100 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit DY252_RS06105 ENOG4108IFG nitrite reductase, (NAD(P)H) DY252_RS06115 ENOG4105DQQ Major facilitator superfamily MFS_1 DY252_RS06125 ENOG4105D7T ABC transporter DY252_RS06140 ENOG410810E transcriptional regulator, lysR family DY252_RS06145 ENOG4105DVW rieske (2Fe-2S) DY252_RS06160 ENOG4108K3Z AraC family transcriptional regulator DY252_RS06175 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DY252_RS06185 ENOG4105C5I Dehydrogenase DY252_RS06195 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) DY252_RS06200 ENOG4105E0C molybdate abc transporter DY252_RS06205 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DY252_RS06215 ENOG41083X2 DNA polymerase III, epsilon subunit DY252_RS06220 ENOG4105C2X Arabinose 5-phosphate isomerase DY252_RS06225 ENOG4107QN1 sodium solute DY252_RS06235 ENOG4105C5H ABC transporter DY252_RS06245 ENOG410903C (LipO)protein DY252_RS06250 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DY252_RS06255 ENOG4105SYT Methylenetetrahydrofolate reductase DY252_RS06260 ENOG4105C3R Methionine synthase DY252_RS06265 ENOG4105C3R Methionine synthase DY252_RS06270 ENOG4105C2C drug resistance transporter, Bcr CflA DY252_RS06285 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase DY252_RS06290 ENOG4105C4R Atp-dependent dna helicase DY252_RS06295 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DY252_RS06305 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DY252_RS06315 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DY252_RS06325 ENOG4105DC7 peptidase M24 DY252_RS06330 ENOG4105CPC Aldo Keto reductase DY252_RS06340 ENOG4106UX7 integral membrane protein DY252_RS06355 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) DY252_RS06365 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DY252_RS06370 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DY252_RS06380 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DY252_RS06385 ENOG4108UFP Essential cell division protein (By similarity) DY252_RS06390 ENOG4105CPF Cell wall formation (By similarity) DY252_RS06395 ENOG4105D4A Cell wall formation (By similarity) DY252_RS06400 ENOG4105DFU Cell wall formation (By similarity) DY252_RS06405 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) DY252_RS06415 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) DY252_RS06420 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) DY252_RS06430 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) DY252_RS06435 ENOG4105CJN penicillin-binding protein DY252_RS06445 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) DY252_RS06450 ENOG4107YUR Cell division protein mraZ DY252_RS06460 ENOG4107QUT magnesium and cobalt transport protein CorA DY252_RS06480 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase DY252_RS06490 ENOG4105C5H ABC transporter DY252_RS06495 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) DY252_RS06500 ENOG4108NVR Methyl-accepting chemotaxis DY252_RS06515 ENOG4105CHR reductase DY252_RS06530 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS06540 ENOG4105CBC glutamate synthase DY252_RS06545 ENOG4105YCT UPF0386 protein DY252_RS06550 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) DY252_RS06565 ENOG4105CQB FAD linked oxidase domain protein DY252_RS06585 ENOG4108GAE asmA family DY252_RS06590 ENOG4105CJ3 phosphate transporter DY252_RS06595 ENOG4105EX9 Membrane DY252_RS06600 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) DY252_RS06605 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) DY252_RS06610 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) DY252_RS06615 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) DY252_RS06620 ENOG4108X4D Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DY252_RS06635 ENOG4105BZU Histidine kinase DY252_RS06645 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DY252_RS06650 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme DY252_RS06665 ENOG4108RW8 Universal stress protein F DY252_RS06675 ENOG4105E6M Sulphatase-modifying factor protein DY252_RS06685 ENOG4105KNK cytochrome C DY252_RS06695 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS06705 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS06720 ENOG4105EAH synthase DY252_RS06730 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DY252_RS06740 ENOG4107QIB glycyl-tRNA synthetase, alpha subunit DY252_RS06745 ENOG4105C38 Glycyl-tRNA synthetase beta subunit DY252_RS06750 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) DY252_RS06760 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) DY252_RS06775 ENOG4105CAQ asparagine synthetase DY252_RS06790 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family DY252_RS06825 ENOG4105DHP deoxycytidine triphosphate deaminase DY252_RS06830 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DY252_RS06835 ENOG4107VBH Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) DY252_RS06840 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DY252_RS06845 ENOG4108ZTZ UPF0262 protein DY252_RS06860 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) DY252_RS06865 ENOG4108Z03 MAF-like protein DY252_RS06870 ENOG4107QQB Ribonuclease E DY252_RS06875 ENOG4105VYE Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) DY252_RS06895 ENOG4105CVP deoxyribo-dipyrimidine photolyase DY252_RS06910 ENOG4105D53 Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity) DY252_RS06920 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase DY252_RS06930 ENOG4105C7K acetolactate synthase DY252_RS06935 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) DY252_RS06940 ENOG4105EAC phosphoserine phosphatase DY252_RS06960 ENOG4107QJR hflk protein DY252_RS06965 ENOG4105D1F ATP-binding protein DY252_RS06975 ENOG4107QIK phosphoribosylformylglycinamidine synthase DY252_RS06980 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I DY252_RS06990 ENOG4107QPR SAICAR synthetase DY252_RS07005 ENOG4105WH1 Two component transcriptional regulator luxr family DY252_RS07010 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) DY252_RS07015 ENOG4108Q5Y Membrane DY252_RS07020 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS07025 ENOG4108V1U phospholipid-binding protein DY252_RS07030 ENOG4105C83 adenylosuccinate lyase DY252_RS07035 ENOG4108ESY Metal dependent phosphohydrolase DY252_RS07040 ENOG4108JQ7 (ABC) transporter DY252_RS07045 ENOG4105C3U ABC transporter DY252_RS07050 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS07055 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS07060 ENOG4108J59 Extracellular solute-binding protein, family 5 DY252_RS07075 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase DY252_RS07080 ENOG4105W5Q DNA repair protein (RadC DY252_RS07085 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DY252_RS07090 ENOG4105PW4 Sugar fermentation stimulation protein homolog DY252_RS07105 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DY252_RS07115 ENOG4105HEI LysR family (Transcriptional regulator DY252_RS07120 ENOG4107VCP Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) DY252_RS07125 ENOG4105VW4 glutaredoxin 3 DY252_RS07170 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) DY252_RS07175 ENOG4105CFH Aspartokinase DY252_RS07180 ENOG4105EA8 2-Nitropropane dioxygenase DY252_RS07185 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase DY252_RS07195 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) DY252_RS07205 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) DY252_RS07210 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) DY252_RS07215 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) DY252_RS07235 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DY252_RS07245 ENOG4108QD6 DY252_RS07250 ENOG4108IQE Amp-dependent synthetase and ligase DY252_RS07265 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DY252_RS07270 ENOG4105W8H transhydrogenase (subunit alpha DY252_RS07275 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DY252_RS07295 ENOG4105K5G 30S ribosomal protein S21 DY252_RS07310 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DY252_RS07325 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit DY252_RS07330 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DY252_RS07365 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DY252_RS07375 ENOG4105DUM transcriptional regulator, lysR family DY252_RS07380 ENOG4105E98 transcriptional regulator DeoR family DY252_RS07410 ENOG41082FS 50S ribosomal protein L31 DY252_RS07415 ENOG4105XQ6 frataxin-like protein DY252_RS07420 ENOG4105BZ1 (ABC) transporter DY252_RS07425 ENOG4105DR5 peptidase DY252_RS07460 ENOG4107YXA Transcriptional regulator, BadM Rrf2 family DY252_RS07465 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein DY252_RS07470 ENOG4108I5D sulfate abc transporter DY252_RS07505 ENOG4108JU7 Transcriptional regulator DY252_RS07510 ENOG4105E2Y ABC, transporter DY252_RS07515 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DY252_RS07520 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DY252_RS07525 ENOG4105GVF (ABC) transporter DY252_RS07545 ENOG4105CAH Chromate DY252_RS07550 ENOG4107XVH Transcriptional regulator DY252_RS07570 ENOG4105FA0 parb-like partition protein DY252_RS07595 ENOG4105C3F Signal peptidase i DY252_RS07600 ENOG4105E4C Lytic transglycosylase catalytic DY252_RS07740 ENOG4105E39 Enoyl-CoA hydratase DY252_RS07760 ENOG4105HJ8 Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity) DY252_RS07770 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS07780 ENOG4105C2J ABC transporter DY252_RS07785 ENOG4108IV0 ABC, transporter DY252_RS07800 ENOG4105D38 putrescine abc transporter DY252_RS07805 ENOG4105D81 ABC transporter, permease DY252_RS07820 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DY252_RS07825 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DY252_RS07835 ENOG4105EMU Dehydrogenase DY252_RS07840 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS07845 ENOG4105BZU Histidine kinase DY252_RS07860 ENOG4107RSM transcriptional regulator DY252_RS07870 ENOG4107QIZ NADH dehydrogenase DY252_RS07875 ENOG4108JB9 formate dehydrogenase DY252_RS07885 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DY252_RS07890 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DY252_RS07905 ENOG4105JSC dimethylmenaquinone methyltransferase DY252_RS07915 ENOG4105E2R ROK family DY252_RS07930 ENOG4108HWW ABC transporter DY252_RS07935 ENOG4105DFW ABC transporter DY252_RS07940 ENOG4105FGE Short-chain dehydrogenase reductase Sdr DY252_RS07945 ENOG4105C01 Dihydroxy-acid dehydratase DY252_RS07960 ENOG4105CBC glutamate synthase DY252_RS07965 ENOG4105M90 Glutamate synthase alpha subunit domain protein DY252_RS07970 ENOG4105EYU Glutamine amido-transferase DY252_RS07980 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DY252_RS07990 ENOG4105E3J oxidoreductase DY252_RS08005 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DY252_RS08015 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS08020 ENOG4105DDR sarcosine oxidase (Beta subunit) DY252_RS08025 ENOG4105WIU sarcosine oxidase delta subunit DY252_RS08030 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) DY252_RS08045 ENOG4105CWC Acetylornithine deacetylase DY252_RS08050 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DY252_RS08065 ENOG41066VF YeeE YedE family protein DY252_RS08075 ENOG4105C1J atp-dependent rna helicase DY252_RS08085 ENOG41073TP transcriptional regulator DY252_RS08095 ENOG4105DRP amino acid AbC transporter DY252_RS08100 ENOG4105E5Q amino acid AbC transporter DY252_RS08115 ENOG4108UPT UPF0178 protein DY252_RS08135 ENOG4105CKI cobalamin synthesis protein DY252_RS08140 ENOG4105KAV tspo and mbr like protein DY252_RS08150 ENOG41080BE Methyl-accepting chemotaxis sensory transducer DY252_RS08155 ENOG4105CYM Glutathione S-transferase DY252_RS08160 ENOG4105CYM Glutathione S-transferase DY252_RS08165 ENOG4105CSH Transporter DY252_RS08170 ENOG4105E2S oxidase) subunit II DY252_RS08175 ENOG4105BZ9 Cytochrome C oxidase, subunit I DY252_RS08180 ENOG4105CCU oxidase (Subunit III) DY252_RS08185 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) DY252_RS08200 ENOG4108SHQ Glutathione S-transferase DY252_RS08210 ENOG4105DXX methyltransferase DY252_RS08215 ENOG4105YA8 Transcriptional regulator DY252_RS08225 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) DY252_RS08245 ENOG4107GFK fumarate DY252_RS08255 ENOG4108IPJ Membrane DY252_RS08265 ENOG4108KK1 membrane protein AbrB duplication DY252_RS08305 ENOG41084GC stage II sporulation protein DY252_RS08310 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS08335 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DY252_RS08345 ENOG4105CNI cell division protein FtsW DY252_RS08350 ENOG4105CJN penicillin-binding protein DY252_RS08360 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DY252_RS08375 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DY252_RS08380 ENOG410829K Lysine exporter protein (Lyse ygga) DY252_RS08395 ENOG4106TD9 Diguanylate cyclase DY252_RS08410 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DY252_RS08435 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) DY252_RS08440 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor DY252_RS08460 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DY252_RS08480 ENOG4105CHR reductase DY252_RS08490 ENOG4105VMP Transcriptional regulator DY252_RS08505 ENOG4105C59 p-type ATPase DY252_RS08510 ENOG4107SS6 2-dehydro-3-deoxygluconokinase DY252_RS08520 ENOG4107RP9 extracellular solute-binding protein, family 3 DY252_RS08525 ENOG4105DRP amino acid AbC transporter DY252_RS08530 ENOG4105E5Q amino acid AbC transporter DY252_RS08540 ENOG4105KME endoribonuclease L-psp DY252_RS08580 ENOG4105C26 Dehydrogenase DY252_RS08585 ENOG4105EV9 Alpha Beta Hydrolase DY252_RS08590 ENOG4107VIJ nudix hydrolase DY252_RS08610 ENOG4107T3P ABC, transporter DY252_RS08625 ENOG4105CG3 alpha amylase, catalytic region DY252_RS08630 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS08635 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase DY252_RS08640 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) DY252_RS08645 ENOG4105C01 Dihydroxy-acid dehydratase DY252_RS08650 ENOG4105CHC glucokinase (EC 2.7.1.2) DY252_RS08655 ENOG4108UHU Aldolase DY252_RS08670 ENOG4105K6V RNA polymerase DY252_RS08710 ENOG4105ED1 spovr family DY252_RS08715 ENOG4106AKX UPF0229 protein DY252_RS08720 ENOG4105CYN Serine protein kinase DY252_RS08725 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) DY252_RS08735 ENOG4108UQ8 endoribonuclease L-psp DY252_RS08750 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS08755 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ DY252_RS08760 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS08795 ENOG4105C2N RNA methyltransferase TrmH family group 3 DY252_RS08810 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DY252_RS08820 ENOG410683Z Preprotein translocase SecE subunit DY252_RS08830 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) DY252_RS08835 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) DY252_RS08840 ENOG4108VZM 50s ribosomal protein L10 DY252_RS08845 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) DY252_RS08850 ENOG4107QIH DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DY252_RS08855 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DY252_RS08860 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) DY252_RS08865 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) DY252_RS08870 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) DY252_RS08875 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) DY252_RS08880 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) DY252_RS08885 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) DY252_RS08890 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DY252_RS08895 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) DY252_RS08900 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity DY252_RS08905 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) DY252_RS08910 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) DY252_RS08915 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) DY252_RS08920 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) DY252_RS08925 ENOG41083MP 50s ribosomal protein l29 DY252_RS08930 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal DY252_RS08935 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) DY252_RS08940 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) DY252_RS08945 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits DY252_RS08950 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) DY252_RS08955 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) DY252_RS08960 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) DY252_RS08965 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) DY252_RS08970 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) DY252_RS08975 ENOG41084HQ 50S ribosomal protein L30 DY252_RS08980 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) DY252_RS08985 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DY252_RS08990 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) DY252_RS08995 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits DY252_RS09000 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) DY252_RS09005 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) DY252_RS09010 ENOG4108ZT0 50S ribosomal protein l17 DY252_RS09015 ENOG4105C0H protease DY252_RS09025 ENOG4105D1H recombination factor protein RarA DY252_RS09030 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DY252_RS09040 ENOG41082CG Protein CrcB homolog DY252_RS09045 ENOG4105EI2 Pseudouridine synthase DY252_RS09055 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DY252_RS09070 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) DY252_RS09075 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DY252_RS09095 ENOG4105BZU Histidine kinase DY252_RS09105 ENOG4107QX3 carboxylase DY252_RS09130 ENOG41084X4 Acylphosphatase (EC 3.6.1.7) DY252_RS09160 ENOG4105CQB FAD linked oxidase domain protein DY252_RS09165 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) DY252_RS09170 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase DY252_RS09180 ENOG41074MP UPF0103 Mediator of ErbB2-driven cell motility-containing protein DY252_RS09205 ENOG4105KEG ribosomal-protein-alanine acetyltransferase DY252_RS09220 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) DY252_RS09230 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS09235 ENOG4108UMI ABC transporter, permease DY252_RS09240 ENOG4105D01 (LipO)protein DY252_RS09255 ENOG4105C57 major facilitator superfamily DY252_RS09270 ENOG4105VDM plasmid maintenance system antidote protein, xre family DY252_RS09275 ENOG41080ET plasmid maintenance system killer protein DY252_RS09295 ENOG4105C5H ABC transporter DY252_RS09300 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) DY252_RS09330 ENOG4108V3E phosphoribosylglycinamide formyltransferase DY252_RS09335 ENOG4105CXB phosphoribosylaminoimidazole synthetase DY252_RS09345 ENOG4105C02 permease DY252_RS09350 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) DY252_RS09355 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) DY252_RS09360 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) DY252_RS09370 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) DY252_RS09430 ENOG4105C9M aspartyl-trna synthetase DY252_RS09450 ENOG41080HT Transcriptional regulator, arsr family DY252_RS09480 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) DY252_RS09485 ENOG4107EXU Short-chain dehydrogenase reductase Sdr DY252_RS09495 ENOG4105CEY Amp-dependent synthetase and ligase DY252_RS09505 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS09515 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS09520 ENOG4105DRR Transcriptional regulator, GntR family DY252_RS09525 ENOG4105DX0 Hemolysin A DY252_RS09560 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH DY252_RS09565 ENOG4107S2Z UPF0761 membrane protein DY252_RS09580 ENOG4108IQE Amp-dependent synthetase and ligase DY252_RS09590 ENOG4105EGS Mechanosensitive ion channel DY252_RS09595 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) DY252_RS09605 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) DY252_RS09610 ENOG41080HT Transcriptional regulator, arsr family DY252_RS09625 ENOG4108RAV Conserved protein DY252_RS09630 ENOG4106PGW Short-chain dehydrogenase reductase Sdr DY252_RS09635 ENOG4108YYD acetyltransferase DY252_RS09650 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DY252_RS09665 ENOG4105DUM transcriptional regulator, lysR family DY252_RS09680 ENOG4107SW0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) DY252_RS09690 ENOG4105CHH sulfate transporter DY252_RS09705 ENOG4105C2C drug resistance transporter, Bcr CflA DY252_RS09715 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS09720 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ DY252_RS09725 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS09730 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS09735 ENOG4105CQZ Histidine kinase DY252_RS09750 ENOG4105D4P Coproporphyrinogen iii oxidase DY252_RS09765 ENOG4107U5X Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) DY252_RS09770 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS09780 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) DY252_RS09790 ENOG4107YCY Transcriptional regulator DY252_RS09800 ENOG4106KXD ATP-dependent carboxylate-amine ligase (By similarity) DY252_RS09865 ENOG4105DKK Benzoate DY252_RS09870 ENOG4105D3R alkyl hydroperoxide reductase DY252_RS09880 ENOG4106VK6 Flagellar motor protein DY252_RS09895 ENOG4105ECY inositol monophosphatase DY252_RS09900 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) DY252_RS09905 ENOG4106HMZ Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DY252_RS09925 ENOG4105CV1 Transketolase (EC 2.2.1.1) DY252_RS09945 ENOG4105D48 metallophosphoesterase DY252_RS09955 ENOG4105C8Q Methyl-accepting chemotaxis DY252_RS09960 ENOG4105CDY transcriptional regulatory protein DY252_RS09965 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) DY252_RS09970 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) DY252_RS09975 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) DY252_RS09980 ENOG4107YD3 Thioesterase DY252_RS09985 ENOG4105E02 MotA TolQ exbB proton channel DY252_RS09990 ENOG4108ZZF transport protein (ExbD) DY252_RS10000 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) DY252_RS10005 ENOG4105KCK Peptidoglycan-associated lipoprotein DY252_RS10015 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) DY252_RS10020 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DY252_RS10025 ENOG4105EEI dihydropteroate synthase DY252_RS10030 ENOG4108KXV response regulator DY252_RS10040 ENOG4105C08 Histidine kinase DY252_RS10045 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) DY252_RS10050 ENOG4105DWF phosphomethylpyrimidine kinase DY252_RS10070 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase DY252_RS10085 ENOG4105DCF alanine dehydrogenase DY252_RS10090 ENOG4108YXU transcriptional regulator AsnC family DY252_RS10100 ENOG4105D38 putrescine abc transporter DY252_RS10105 ENOG4105F38 ABC transporter, permease DY252_RS10110 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS10115 ENOG4107RUE extracellular solute-binding protein family 1 DY252_RS10120 ENOG4105CFQ glutamine synthetase DY252_RS10130 ENOG4107S8C mandelate racemase muconate lactonizing DY252_RS10135 ENOG4105EQR Transposase IS116 IS110 IS902 DY252_RS10165 ENOG4105CMI transporter DY252_RS10170 ENOG4105CJ1 ABC, transporter DY252_RS10175 ENOG4105D0S secretion protein (HlyD DY252_RS10210 ENOG4105M0J Toxic component of a toxin-antitoxin (TA) module. A DY252_RS10215 ENOG4105VGJ Virulence-associated protein DY252_RS10230 ENOG4105CQB FAD linked oxidase domain protein DY252_RS10235 ENOG4105D5K Hemolysin activator protein DY252_RS10265 ENOG4105CYW agmatinase DY252_RS10270 ENOG4105EVZ LysR family transcriptional regulator DY252_RS10280 ENOG4105C26 Dehydrogenase DY252_RS10285 ENOG4106NZI LysR family Transcriptional regulator DY252_RS10300 ENOG4108UW5 maltose o-acetyltransferase DY252_RS10320 ENOG4105ECM Sensor protein basS pmrB DY252_RS10325 ENOG4105ETE Transcriptional regulator (LacI family DY252_RS10330 ENOG4105CY5 solute-binding protein DY252_RS10335 ENOG4105E0C molybdate abc transporter DY252_RS10345 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS10350 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DY252_RS10365 ENOG4105ECP epimerase DY252_RS10375 ENOG4108M0I Transcriptional regulator DY252_RS10390 ENOG4105DIJ Phosphoethanolamine transferase DY252_RS10430 ENOG4107RTZ reductase DY252_RS10450 ENOG4106ECF Uncharacterized protein conserved in bacteria (DUF2155) DY252_RS10460 ENOG4108YYC ycei family DY252_RS10465 ENOG4105DS1 cytochrome b561 DY252_RS10485 ENOG4106KED esterase YpfH DY252_RS10490 ENOG4107R73 Mate efflux family protein DY252_RS10495 ENOG4108YXU transcriptional regulator AsnC family DY252_RS10505 ENOG4105UFH BadM Rrf2 family transcriptional regulator DY252_RS10510 ENOG4105C1J atp-dependent rna helicase DY252_RS10530 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DY252_RS10535 ENOG4105NAU thioesterase Superfamily protein DY252_RS10550 ENOG4108JQ7 (ABC) transporter DY252_RS10555 ENOG4105C3U ABC transporter DY252_RS10560 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS10565 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS10600 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS10605 ENOG4107YWA deoxycytidylate deaminase DY252_RS10610 ENOG4105CA9 Pyruvate kinase DY252_RS10630 ENOG4107R7Y intracellular protease Pfpi family DY252_RS10635 ENOG4105D64 Mechanosensitive ion channel DY252_RS10640 ENOG4105UYK outer membrane protein a DY252_RS10650 ENOG4105K4P CoA-binding domain protein DY252_RS10655 ENOG4105DQ2 Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity) DY252_RS10665 ENOG410829K Lysine exporter protein (Lyse ygga) DY252_RS10690 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) DY252_RS10695 ENOG4108UJD 30S ribosomal protein S9 DY252_RS10715 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase DY252_RS10720 ENOG4105FAW cDP-glucose 4,6-dehydratase DY252_RS10725 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase DY252_RS10760 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase DY252_RS10765 ENOG4108Z0R Transferase DY252_RS10775 ENOG4106KE4 Dehydrogenase DY252_RS10780 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class DY252_RS10790 ENOG4105CHM Aminotransferase DY252_RS10795 ENOG4105D6E homoserine dehydrogenase DY252_RS10800 ENOG4105CBT Fructose-1,6-bisphosphatase DY252_RS10805 ENOG4105CFG Acts as a chaperone (By similarity) DY252_RS10820 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) DY252_RS10825 ENOG4107R3J Transporter DY252_RS10845 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) DY252_RS10865 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DY252_RS10870 ENOG4106VK6 Flagellar motor protein DY252_RS10875 ENOG4108217 motA TolQ ExbB proton channel DY252_RS10895 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) DY252_RS10915 ENOG4105C28 cystathionine DY252_RS10920 ENOG4105MWK D-amino acid dehydrogenase, small subunit DY252_RS10930 ENOG4105E8R UPF0173 metal-dependent hydrolase DY252_RS10935 ENOG4107Z6I Thiamine biosynthesis protein DY252_RS10940 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component DY252_RS10945 ENOG4108YI8 ABC transporter DY252_RS10965 ENOG4105DGU Histone deacetylase DY252_RS11000 ENOG4105CV8 reductase DY252_RS11005 ENOG4105CKI cobalamin synthesis protein DY252_RS11010 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DY252_RS11025 ENOG4105FAV ABC, transporter DY252_RS11035 ENOG4105C28 cystathionine DY252_RS11040 ENOG4105C7B Threonine dehydratase DY252_RS11045 ENOG41082R8 50S ribosomal protein l32 DY252_RS11060 ENOG4105KHC sulfurtransferase DY252_RS11065 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DY252_RS11090 ENOG4105N14 lysine exporter protein LysE YggA DY252_RS11100 ENOG4105DEN Luciferase family DY252_RS11115 ENOG4105D94 Major Facilitator Superfamily DY252_RS11120 ENOG4105C6T cysteine synthase DY252_RS11125 ENOG41087AY ADP-Ribose pyrophosphatase DY252_RS11130 ENOG4105BZU Histidine kinase DY252_RS11140 ENOG4105CIN aminoacyl-histidine dipeptidase DY252_RS11145 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) DY252_RS11155 ENOG4105YK5 50S ribosomal protein L36 DY252_RS11195 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) DY252_RS11210 ENOG4105BZU Histidine kinase DY252_RS11215 ENOG4105BZU Histidine kinase DY252_RS11220 ENOG4105BZU Histidine kinase DY252_RS11235 ENOG4105DAN ATP-dependent protease DY252_RS11240 ENOG4107SQD Transcriptional regulator, GntR family DY252_RS11250 ENOG4105C7B Threonine dehydratase DY252_RS11260 ENOG4105JAB phenazine biosynthesis protein, phzf family DY252_RS11275 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) DY252_RS11280 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DY252_RS11315 ENOG4108IJ7 Glycine betaine DY252_RS11320 ENOG4108HQS Glycine betaine DY252_RS11360 ENOG4105CY0 Metallo-Beta-Lactamase DY252_RS11370 ENOG4107T8Q Glycosyl transferase (Group 1 DY252_RS11415 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS11430 ENOG4105D8G Major Facilitator superfamily DY252_RS11435 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) DY252_RS11440 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DY252_RS11445 ENOG4105KUZ arsenate reductase DY252_RS11450 ENOG4107YBY Hydrolase DY252_RS11455 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DY252_RS11475 ENOG4105W0E 50S ribosomal protein L33 DY252_RS11480 ENOG4105CN1 protease DY252_RS11495 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) DY252_RS11500 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) DY252_RS11510 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) DY252_RS11535 ENOG4107ZJC Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DY252_RS11540 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS11550 ENOG4105F38 ABC transporter, permease DY252_RS11560 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DY252_RS11565 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DY252_RS11570 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DY252_RS11580 ENOG4105C59 p-type ATPase DY252_RS11590 ENOG4105CR8 Transcriptional regulator DY252_RS11595 ENOG4107104 thymidine kinase DY252_RS11605 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) DY252_RS11610 ENOG4105F1S paraquat-inducible protein a DY252_RS11615 ENOG4105DY2 Paraquat-inducible protein b DY252_RS11630 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS11675 ENOG4105DD7 kinase (PfkB family DY252_RS11680 ENOG4105CGH 5'-nucleotidase DY252_RS11685 ENOG4105DIH basic membrane DY252_RS11690 ENOG4108JQ9 ABC transporter DY252_RS11710 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) DY252_RS11715 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DY252_RS11720 ENOG4105E98 transcriptional regulator DeoR family DY252_RS11725 ENOG4105DHJ ABC, transporter DY252_RS11730 ENOG4105CDA abc transporter atp-binding protein DY252_RS11735 ENOG4105DRP amino acid AbC transporter DY252_RS11740 ENOG4105EZ7 amino acid ABC transporter DY252_RS11745 ENOG4107QXX ABC transporter DY252_RS11750 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DY252_RS11755 ENOG4108RIR Molybdenum cofactor biosynthesis protein DY252_RS11775 ENOG41069M3 Transcriptional regulator DY252_RS11780 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) DY252_RS11810 ENOG4105C22 threonyL-tRNA synthetase DY252_RS11815 ENOG4105DXI Major Facilitator superfamily DY252_RS11840 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DY252_RS11845 ENOG4105D1Q UPF0246 protein DY252_RS11850 ENOG4107QYG anthranilate phosphoribosyltransferase DY252_RS11865 ENOG4107XQ1 cobalamin (vitamin B12) biosynthesis CbiM protein DY252_RS11900 ENOG4105CD5 CoA-binding domain protein DY252_RS11925 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor DY252_RS11930 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) DY252_RS11935 ENOG4105C72 UPF0176 protein DY252_RS11940 ENOG4105DFG type I secretion outer membrane protein DY252_RS11950 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) DY252_RS11955 ENOG4105CRQ synthase (Component I) DY252_RS11960 ENOG4105DDQ anthranilate synthase DY252_RS11975 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DY252_RS11985 ENOG4108YX9 iron--sulfur cluster insertion protein erpA DY252_RS11990 ENOG4105C75 arginyL-tRNA synthetase DY252_RS12000 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) DY252_RS12005 ENOG4108Z4T Peptidase M50 DY252_RS12010 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) DY252_RS12015 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DY252_RS12020 ENOG4108IJ6 ABC transporter DY252_RS12030 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) DY252_RS12035 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) DY252_RS12040 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) DY252_RS12045 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) DY252_RS12050 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) DY252_RS12055 ENOG4108K5P (LipO)protein DY252_RS12065 ENOG4105VIE preprotein translocase, subunit YajC DY252_RS12080 ENOG4108UIV Protein of unknown function (DUF498/DUF598) DY252_RS12085 ENOG4107S11 squalene-associated FAD-dependent desaturase DY252_RS12090 ENOG4105D64 Mechanosensitive ion channel DY252_RS12105 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) DY252_RS12115 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) DY252_RS12120 ENOG4105D2N Aldolase DY252_RS12125 ENOG4105CE4 GlcNAc 6-P deacetylase DY252_RS12155 ENOG4108UUM single-stranded DNA-binding protein DY252_RS12190 ENOG4105CB5 ATP-dependent DNA helicase recG DY252_RS12210 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) DY252_RS12215 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) DY252_RS12235 ENOG4105E89 ABC transporter DY252_RS12240 ENOG4108JEH abc transporter atp-binding protein DY252_RS12245 ENOG4105C8Q Methyl-accepting chemotaxis DY252_RS12260 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DY252_RS12270 ENOG4107S90 membrAne DY252_RS12275 ENOG4105CVE Lytic murein transglycosylase DY252_RS12285 ENOG4105DZ1 carboxypeptidase DY252_RS12290 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) DY252_RS12295 ENOG4107QRG dna polymerase iii DY252_RS12305 ENOG4105F8V Hydrolase, tatD family DY252_RS12310 ENOG4108H5C Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) DY252_RS12335 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) DY252_RS12385 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DY252_RS12395 ENOG4105C2D reductase DY252_RS12400 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DY252_RS12410 ENOG4105CNN ABC, transporter DY252_RS12420 ENOG4105C2J ABC transporter DY252_RS12430 ENOG4105BZU Histidine kinase DY252_RS12440 ENOG4105DHQ Histidine kinase DY252_RS12460 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DY252_RS12490 ENOG4108KK1 membrane protein AbrB duplication DY252_RS12495 ENOG4107S7U Sulfide dehydrogenase DY252_RS12510 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) DY252_RS12545 ENOG4107QIV Cytochrome c biogenesis protein DY252_RS12560 ENOG4105CUC YeeE YedE family protein DY252_RS12580 ENOG4108JPW Aminotransferase DY252_RS12585 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) DY252_RS12590 ENOG4105CZK Aspartate kinase DY252_RS12595 ENOG4105DXN mazG family DY252_RS12600 ENOG4107TK4 histidinol-phosphate phosphatase DY252_RS12605 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) DY252_RS12610 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DY252_RS12620 ENOG4105C1A potassium transporter peripheral membrane DY252_RS12625 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS12655 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) DY252_RS12665 ENOG4105VF7 tolerance protein DY252_RS12685 ENOG4105WJX transcriptional regulator MERR family DY252_RS12690 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DY252_RS12695 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) DY252_RS12700 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) DY252_RS12720 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DY252_RS12725 ENOG4107XZX Involved in the transcription termination process (By similarity) DY252_RS12730 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) DY252_RS12735 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DY252_RS12745 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) DY252_RS12750 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) DY252_RS12755 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) DY252_RS12760 ENOG4108YZG isomerase DY252_RS12770 ENOG4105CP9 extracellular ligand-binding receptor DY252_RS12780 ENOG4108IV0 ABC, transporter DY252_RS12785 ENOG4105C0Z ABC transporter DY252_RS12790 ENOG4105CF8 branched-chain amino acid ABC transporter, permease DY252_RS12795 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS12810 ENOG4105E39 Enoyl-CoA hydratase DY252_RS12815 ENOG4105C1G acyl-Coa dehydrogenase DY252_RS12825 ENOG4105E98 transcriptional regulator DeoR family DY252_RS12835 ENOG4105D52 delta-aminolevulinic acid dehydratase DY252_RS12840 ENOG4105PAD Hydrolase DY252_RS12850 ENOG4105CEY Amp-dependent synthetase and ligase DY252_RS12860 ENOG4105C26 Dehydrogenase DY252_RS12865 ENOG4105C7B Threonine dehydratase DY252_RS12875 ENOG4107RD7 Flagellar Motor Protein, MotA DY252_RS12880 ENOG4105ER2 Ompa motb domain protein DY252_RS12885 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate DY252_RS12890 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS12895 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS12905 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DY252_RS12910 ENOG4107UIS Involved in DNA repair and RecF pathway recombination (By similarity) DY252_RS12925 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) DY252_RS12930 ENOG4105C3F Signal peptidase i DY252_RS12935 ENOG4105KJV Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) DY252_RS12940 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) DY252_RS12955 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) DY252_RS12970 ENOG4105E50 uracil-dna glycosylase DY252_RS12975 ENOG4105C9U ATP-dependent DNA helicase RecQ DY252_RS12980 ENOG4108V06 Glutathione peroxidase DY252_RS12990 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) DY252_RS12995 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DY252_RS13000 ENOG4105E4C Lytic transglycosylase catalytic DY252_RS13015 ENOG4105DR5 peptidase DY252_RS13020 ENOG4108ZAI phosphatidylglycerophosphatase a DY252_RS13025 ENOG4108I62 cina-like protein DY252_RS13030 ENOG4108Z1B Cyclase dehydrase DY252_RS13035 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DY252_RS13040 ENOG4107QN2 dihydrolipoyl dehydrogenase DY252_RS13045 ENOG4105C7S Dehydrogenase DY252_RS13050 ENOG4105CPP Dehydrogenase, E1 component DY252_RS13055 ENOG4108JYK Dehydrogenase DY252_RS13065 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) DY252_RS13075 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) DY252_RS13085 ENOG4105CP7 Triose-phosphate isomerase DY252_RS13090 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) DY252_RS13095 ENOG4105CRQ synthase (Component I) DY252_RS13100 ENOG4105PXI polysaccharide deacetylase DY252_RS13105 ENOG4105DDQ anthranilate synthase DY252_RS13110 ENOG4107QYG anthranilate phosphoribosyltransferase DY252_RS13115 ENOG4105DK0 Indole-3-glycerol phosphate synthase DY252_RS13120 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DY252_RS13125 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) DY252_RS13130 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 DY252_RS13135 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) DY252_RS13140 ENOG4105BZN citrate synthase DY252_RS13150 ENOG4105E82 cytochrome subunit of dehydrogenase DY252_RS13155 ENOG4105ETT transcriptional Regulator, LysR family DY252_RS13165 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DY252_RS13170 ENOG4105GYT Protein of unknown function (DUF1009) DY252_RS13175 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DY252_RS13180 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) DY252_RS13185 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DY252_RS13195 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DY252_RS13200 ENOG4105DZP Membrane-associated zinc metalloprotease DY252_RS13205 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) DY252_RS13215 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) DY252_RS13220 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) DY252_RS13225 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) DY252_RS13230 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) DY252_RS13235 ENOG4105CE9 30S ribosomal protein S2 DY252_RS13245 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DY252_RS13255 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) DY252_RS13280 ENOG4107QNB Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) DY252_RS13285 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase DY252_RS13290 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DY252_RS13295 ENOG4105C8S subunit m DY252_RS13300 ENOG4105D65 subunit l DY252_RS13305 ENOG4105M5H NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DY252_RS13310 ENOG4105DF2 NADH dehydrogenase subunit j DY252_RS13315 ENOG4105P3U NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DY252_RS13320 ENOG4105CMZ NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity) DY252_RS13330 ENOG4107QIZ NADH dehydrogenase DY252_RS13340 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DY252_RS13345 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DY252_RS13350 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) DY252_RS13355 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain DY252_RS13365 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) DY252_RS13385 ENOG4105K70 DNA-binding protein DY252_RS13390 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) DY252_RS13395 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) DY252_RS13400 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DY252_RS13405 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation DY252_RS13420 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DY252_RS13425 ENOG4105MWK D-amino acid dehydrogenase, small subunit DY252_RS13430 ENOG4105BZU Histidine kinase DY252_RS13445 ENOG4105C59 p-type ATPase DY252_RS13455 ENOG4108UQY Iron-storage protein DY252_RS13460 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein DY252_RS13465 ENOG4105CVP deoxyribo-dipyrimidine photolyase DY252_RS13495 ENOG4105DRS transport system, permease DY252_RS13500 ENOG4108IJ9 (ABC) transporter DY252_RS13505 ENOG4105E0F Histidine kinase DY252_RS13520 ENOG4108QDE fad dependent oxidoreductase DY252_RS13535 ENOG4107QP8 phosphohexose isomerase DY252_RS13540 ENOG4105D7K pfkb domain protein DY252_RS13555 ENOG4105CYW agmatinase DY252_RS13560 ENOG4105C26 Dehydrogenase DY252_RS13565 ENOG4107VRI Transcriptional regulator DY252_RS13570 ENOG4105CFQ glutamine synthetase DY252_RS13575 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DY252_RS13595 ENOG4105CJP fad dependent oxidoreductase DY252_RS13610 ENOG4105C26 Dehydrogenase DY252_RS13625 ENOG4108HQS Glycine betaine DY252_RS13630 ENOG4108IJ7 Glycine betaine DY252_RS13640 ENOG4108KB2 LysR family Transcriptional regulator DY252_RS13650 ENOG4105D38 putrescine abc transporter DY252_RS13660 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS13665 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DY252_RS13670 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme DY252_RS13680 ENOG4105FC8 fad dependent oxidoreductase DY252_RS13685 ENOG4107S4Y M20 DapE family protein YgeY DY252_RS13710 ENOG4105CIF Ornithine Cyclodeaminase DY252_RS13725 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS13730 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS13740 ENOG4106KNT transcriptional regulator DY252_RS13750 ENOG4105CFU surface antigen DY252_RS13770 ENOG4105EQR Transposase IS116 IS110 IS902 DY252_RS13790 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase DY252_RS13795 ENOG4105CHU acetyl-coa acetyltransferase DY252_RS13825 ENOG4105F2Z 3-oxoadipate enol-lactonase DY252_RS13830 ENOG4105DDW LysR family Transcriptional regulator DY252_RS13845 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS13855 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DY252_RS13860 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) DY252_RS13875 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DY252_RS13885 ENOG4105C0R drug resistance transporter emrb qaca subfamily DY252_RS13895 ENOG4105Q26 Siderophore-interacting protein DY252_RS13905 ENOG4105E2A Dehydrogenase DY252_RS13930 ENOG4108UGV hypoxanthine phosphoribosyltransferase DY252_RS13950 ENOG4108ZFX Mannosyl-3-phosphoglycerate phosphatase DY252_RS13955 ENOG4105C3Q Glycosyl transferase, family 2 DY252_RS13970 ENOG4107QW3 Sucrose phosphorylase DY252_RS13985 ENOG4108Z7F N-acetyltransferase DY252_RS14020 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) DY252_RS14035 ENOG4107EJG GntR family transcriptional regulator DY252_RS14040 ENOG41062B0 ABC transporter, permease DY252_RS14045 ENOG4107R9N ABC transporter DY252_RS14050 ENOG4105C2J ABC transporter DY252_RS14055 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator DY252_RS14060 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) DY252_RS14065 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DY252_RS14070 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS14080 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS14085 ENOG4105DRR Transcriptional regulator, GntR family DY252_RS14090 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS14155 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) DY252_RS14170 ENOG4105CD8 aminopeptidase N DY252_RS14190 ENOG410829K Lysine exporter protein (Lyse ygga) DY252_RS14210 ENOG4105BZU Histidine kinase DY252_RS14220 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS14225 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS14245 ENOG4105X58 receptor DY252_RS14250 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) DY252_RS14265 ENOG4109015 Biopolymer transport protein exbD tolR DY252_RS14295 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) DY252_RS14330 ENOG4105EKE dihydroorotase DY252_RS14365 ENOG410642W LysR family Transcriptional regulator DY252_RS14375 ENOG4105CHM Aminotransferase DY252_RS14380 ENOG4108YZA Nitrogen regulatory protein pii DY252_RS14385 ENOG4105C5F glutamine synthetase DY252_RS14390 ENOG4107RDJ Sulfotransferase DY252_RS14395 ENOG4105BZU Histidine kinase DY252_RS14405 ENOG4108UKZ OsmC family DY252_RS14420 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) DY252_RS14425 ENOG4107RDJ Sulfotransferase DY252_RS14440 ENOG4105BZU Histidine kinase DY252_RS14455 ENOG4107XBN GntR Family Transcriptional Regulator DY252_RS14460 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS14465 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS14470 ENOG4108ERU trap dicarboxylate transporter subunit DctP DY252_RS14475 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS14490 ENOG4107NQ8 LysR family Transcriptional regulator DY252_RS14495 ENOG4105CP9 extracellular ligand-binding receptor DY252_RS14500 ENOG4105C0Z ABC transporter DY252_RS14515 ENOG4105CF8 branched-chain amino acid ABC transporter, permease DY252_RS14535 ENOG4105BZU Histidine kinase DY252_RS14570 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) DY252_RS14575 ENOG4105ETU transcriptional activator (TenA DY252_RS14580 ENOG4105WVQ Fe-S assembly protein IscX DY252_RS14595 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) DY252_RS14600 ENOG4108Z4V iron-sulfur cluster assembly DY252_RS14605 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins DY252_RS14610 ENOG4105C3J Cysteine desulfurase DY252_RS14615 ENOG4107QI6 Cysteine desulfurase DY252_RS14620 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family DY252_RS14625 ENOG4105D7W serine acetyltransferase DY252_RS14630 ENOG4105DHZ alpha beta DY252_RS14635 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) DY252_RS14640 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) DY252_RS14650 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) DY252_RS14655 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DY252_RS14665 ENOG4105ED9 Protein of unknown function (DUF455) DY252_RS14675 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DY252_RS14710 ENOG4108JQC penicillin-binding protein 1A DY252_RS14715 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase DY252_RS14720 ENOG4105C03 ribonuclease DY252_RS14745 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) DY252_RS14750 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) DY252_RS14755 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) DY252_RS14760 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DY252_RS14765 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DY252_RS14770 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) DY252_RS14780 ENOG4108JQ1 Dehydrogenase DY252_RS14810 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) DY252_RS14825 ENOG4105DZ1 carboxypeptidase DY252_RS14835 ENOG4105C6Y Udp-glucose 6-dehydrogenase DY252_RS14840 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DY252_RS14845 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) DY252_RS14865 ENOG4105D5U fad dependent oxidoreductase DY252_RS14870 ENOG4105GSQ TM1410 hypothetical-related protein DY252_RS14880 ENOG4107R37 Glutamate dehydrogenase DY252_RS14905 ENOG41082WC Transport-associated protein DY252_RS14915 ENOG4105EW9 transcriptional regulator AsnC family DY252_RS14930 ENOG4107QX3 carboxylase DY252_RS14935 ENOG4108UKI Enoyl-CoA hydratase DY252_RS14945 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase DY252_RS14975 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DY252_RS15000 ENOG4105CSR polyphosphate kinase 2 DY252_RS15005 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DY252_RS15010 ENOG4105CN1 protease DY252_RS15015 ENOG4105CSU acyl-Coa dehydrogenase DY252_RS15030 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) DY252_RS15035 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) DY252_RS15040 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) DY252_RS15045 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DY252_RS15050 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DY252_RS15055 ENOG4105DSJ YicC domain protein DY252_RS15060 ENOG4107FW0 short-chain dehydrogenase reductase DY252_RS15065 ENOG4105HHA aminodeoxychorismate lyase DY252_RS15070 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DY252_RS15075 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) DY252_RS15085 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DY252_RS15090 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) DY252_RS15095 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) DY252_RS15110 ENOG4105CDU Replicative dna helicase DY252_RS15115 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DY252_RS15125 ENOG4105DHJ ABC, transporter DY252_RS15140 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase DY252_RS15145 ENOG4105UBK short-chain dehydrogenase reductase DY252_RS15180 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) DY252_RS15215 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DY252_RS15245 ENOG4105E3B Multicopper oxidase DY252_RS15300 ENOG4105W1Y Transcriptional regulator DY252_RS15310 ENOG4105DD5 Flagellar motor switch protein DY252_RS15315 ENOG4105C6T cysteine synthase DY252_RS15320 ENOG4105MYT Heat shock protein DY252_RS15325 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DY252_RS15330 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) DY252_RS15335 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) DY252_RS15345 ENOG4105W1Y Transcriptional regulator DY252_RS15375 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DY252_RS15400 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DY252_RS15405 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DY252_RS15415 ENOG4108HWW ABC transporter DY252_RS15425 ENOG4105DFW ABC transporter DY252_RS15440 ENOG4105C7H Helicase, RecD TraA family DY252_RS15450 ENOG4105E0X reductase DY252_RS15460 ENOG4108TGR phosphatase DY252_RS15465 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DY252_RS15470 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS15480 ENOG4107RUE extracellular solute-binding protein family 1 DY252_RS15485 ENOG4105E98 transcriptional regulator DeoR family DY252_RS15565 ENOG4108Q35 Adenylate DY252_RS15570 ENOG4105E0F Histidine kinase DY252_RS15595 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DY252_RS15600 ENOG4105CAQ asparagine synthetase DY252_RS15605 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family DY252_RS15610 ENOG4105C26 Dehydrogenase DY252_RS15620 ENOG4105HMI Membrane DY252_RS15630 ENOG4105C4M (Ubiquinol oxidase) subunit I DY252_RS15635 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DY252_RS15645 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DY252_RS15655 ENOG4105C11 sulfate adenylyltransferase), subunit 2 DY252_RS15675 ENOG4108T9J Cdp-alcohol phosphatidyltransferase DY252_RS15690 ENOG4105VC4 domain protein DY252_RS15705 ENOG4108RTU Aldolase DY252_RS15710 ENOG4105EI3 2-dehydro-3-deoxygalactonokinase EC 2.7.1.58 DY252_RS15720 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) DY252_RS15795 ENOG4105CTU Proline racemase DY252_RS15810 ENOG4105MWK D-amino acid dehydrogenase, small subunit DY252_RS15815 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DY252_RS15830 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) DY252_RS15840 ENOG4105C26 Dehydrogenase DY252_RS15870 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DY252_RS15875 ENOG4108IJ9 (ABC) transporter DY252_RS15890 ENOG4105EB1 binding-protein-dependent transport systems inner membrane Component DY252_RS15910 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) DY252_RS15920 ENOG4105CBN LysR family transcriptional regulator DY252_RS15925 ENOG4105CHR reductase DY252_RS15935 ENOG4105CD3 dihydroorotase DY252_RS15945 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DY252_RS15950 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component DY252_RS15965 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DY252_RS15970 ENOG4108R86 Transcriptional regulator DY252_RS15980 ENOG4105CE7 Amidase, hydantoinase carbamoylase family DY252_RS15985 ENOG4107SJI Dehydrogenase DY252_RS15990 ENOG4105BZ8 glutamate synthase DY252_RS15995 ENOG4105NAU thioesterase Superfamily protein DY252_RS16000 ENOG4105DER m42 family DY252_RS16010 ENOG4108JQ7 (ABC) transporter DY252_RS16020 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS16025 ENOG4105DEF Extracellular solute-binding protein, family 5 DY252_RS16045 ENOG4105BZG amino acid carrier protein DY252_RS16050 ENOG4105CFP Peptidase U32 DY252_RS16065 ENOG4107R3E Citrate transporter DY252_RS16085 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein DY252_RS16090 ENOG4105E0A ABC, transporter DY252_RS16100 ENOG4105J76 Periplasmic binding protein DY252_RS16105 ENOG4105S6R Iron-hydroxamate transporter permease subunit DY252_RS16135 ENOG4105E9Z Nad-dependent epimerase dehydratase DY252_RS16140 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS16150 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS16155 ENOG4105UVJ 5-dehydro-4-deoxyglucarate dehydratase DY252_RS16165 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein DY252_RS16170 ENOG4105JXH GntR family transcriptional regulator DY252_RS16175 ENOG4108ZKT aldose 1-epimerase DY252_RS16180 ENOG4107YCY Transcriptional regulator DY252_RS16185 ENOG4107URF beta-phospho-glucomutase DY252_RS16190 ENOG4105EF1 ribulokinase DY252_RS16195 ENOG4105BZS acriflavin resistance protein DY252_RS16200 ENOG4105C1P efflux transporter, rnd family, mfp subunit DY252_RS16215 ENOG4105E0K tonB-dependent siderophore receptor DY252_RS16225 ENOG4108KPJ rna polymerase sigma factor DY252_RS16245 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase DY252_RS16260 ENOG410642W LysR family Transcriptional regulator DY252_RS16265 ENOG4105DFI Membrane DY252_RS16300 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) DY252_RS16305 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DY252_RS16330 ENOG4105JQN Transcriptional regulator DY252_RS16335 ENOG4105JAB phenazine biosynthesis protein, phzf family DY252_RS16365 ENOG4105VT3 DNA binding domain protein, excisionase family DY252_RS16500 ENOG4105BZU Histidine kinase DY252_RS16505 ENOG4105ECY inositol monophosphatase DY252_RS16540 ENOG4105BZU Histidine kinase DY252_RS16545 ENOG4105BZU Histidine kinase DY252_RS16565 ENOG4105K56 Transcriptional regulator DY252_RS16575 ENOG4108ZHJ Organic hydroperoxide resistance protein DY252_RS16590 ENOG4105W39 Membrane DY252_RS16600 ENOG4108VP3 Lysine exporter protein (LysE YggA) DY252_RS16605 ENOG4106AXJ AraC family transcriptional regulator DY252_RS16610 ENOG4105DVT helicase DY252_RS16630 ENOG4105C59 p-type ATPase DY252_RS16635 ENOG4108YK4 Acid-resistance membrane protein DY252_RS16670 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DY252_RS16685 ENOG41069P5 Protein slyX homolog DY252_RS16700 ENOG4105DCM major facilitator superfamily DY252_RS16715 ENOG4105CC0 LysR family Transcriptional regulator DY252_RS16720 ENOG4105CQ7 ATP-dependent helicase DY252_RS16790 ENOG4107SBE Glycosyl transferase (Group 1 DY252_RS16810 ENOG4105C8T Leucyl-tRNA synthetase DY252_RS16840 ENOG4105I03 Flagellin DY252_RS16845 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DY252_RS16855 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase DY252_RS16860 ENOG4107SPB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DY252_RS16910 ENOG41071I4 Phosphatidylserine decarboxylase proenzyme DY252_RS16925 ENOG4108URH decarboxylase DY252_RS16935 ENOG4108JU3 Alkyl hydroperoxide reductase DY252_RS16940 ENOG4105E98 transcriptional regulator DeoR family DY252_RS16945 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS16960 ENOG4105DRS transport system, permease DY252_RS16965 ENOG4105SKE transcriptional Regulator LysR family DY252_RS16980 ENOG4105CA0 peroxidase DY252_RS16990 ENOG4105EUZ Beta-lactamase domain protein DY252_RS17015 ENOG4105JAB phenazine biosynthesis protein, phzf family DY252_RS17085 ENOG4105EUB pirin domain protein DY252_RS17090 ENOG4105CS1 NAD(P)H quinone oxidoreductase DY252_RS17095 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase DY252_RS17110 ENOG4105T16 Transcriptional regulator (AraC family) DY252_RS17115 ENOG4108R86 Transcriptional regulator DY252_RS17125 ENOG4105F38 ABC transporter, permease DY252_RS17130 ENOG4105D38 putrescine abc transporter DY252_RS17135 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS17170 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) DY252_RS17185 ENOG41065G1 UPF0391 membrane protein DY252_RS17205 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) DY252_RS17270 ENOG4105D00 flagellar biosynthetic protein flhB DY252_RS17275 ENOG4105D19 Role in flagellar biosynthesis (By similarity) DY252_RS17285 ENOG4105UVF flagellar hook-basal body complex protein fliE DY252_RS17290 ENOG4108ZC9 flagellar basal-body rod protein flgc DY252_RS17295 ENOG4105SFI flagellar basal-body rod protein DY252_RS17305 ENOG4105D00 flagellar biosynthetic protein flhB DY252_RS17320 ENOG4105CN7 Flagellar biosynthetic protein FliP DY252_RS17325 ENOG4105CJP fad dependent oxidoreductase DY252_RS17340 ENOG4106VK6 Flagellar motor protein DY252_RS17355 ENOG4108VYJ response regulator receiver protein DY252_RS17380 ENOG4108JQA flagellar DY252_RS17385 ENOG4105CGA flagellar basal-body rod protein FlgG DY252_RS17395 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) DY252_RS17405 ENOG4106909 Flagellar assembly regulator FliX DY252_RS17415 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) DY252_RS17420 ENOG41065XG Chemotactic signal-response protein CheL DY252_RS17435 ENOG4105DTJ flagellar hook-associated protein DY252_RS17450 ENOG4105I03 Flagellin DY252_RS17455 ENOG4105I03 Flagellin DY252_RS17460 ENOG4105I03 Flagellin DY252_RS17480 ENOG4105MQ3 flagellar protein FliS DY252_RS17490 ENOG4105W00 Flagellar hook capping protein DY252_RS17495 ENOG4105BZE flagellar hook protein, FlgE DY252_RS17500 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) DY252_RS17510 ENOG4105DD5 Flagellar motor switch protein DY252_RS17515 ENOG4105E14 MotA TolQ exbB proton channel DY252_RS17520 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS17525 ENOG4105D7B Flagellar biosynthesis protein flha DY252_RS17550 ENOG4107E2E PKHD-type hydroxylase DY252_RS17555 ENOG4108VGW abc transporter atp-binding protein DY252_RS17560 ENOG4105CXZ ABC transporter, permease DY252_RS17565 ENOG4105VNH ABC transporter solute-binding protein DY252_RS17570 ENOG4105EE5 Membrane protein terC DY252_RS17595 ENOG4105EFQ Two component transcriptional regulator (Winged helix family DY252_RS17605 ENOG4105BZU Histidine kinase DY252_RS17610 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) DY252_RS17670 ENOG4105FR1 rard protein DY252_RS17675 ENOG4105M2J Glutaredoxin DY252_RS17680 ENOG4105D8X mechanosensitive ion channel DY252_RS17690 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) DY252_RS17705 ENOG4108IXY short-chain dehydrogenase reductase DY252_RS17710 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DY252_RS17730 ENOG4108ISG Major Facilitator DY252_RS17745 ENOG4105VUF Transcriptional regulator DY252_RS17750 ENOG4108Z8I decarboxylase DY252_RS17755 ENOG4105C8N cysteinyl-tRNA synthetase DY252_RS17760 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) DY252_RS17765 ENOG4105C4K Nad synthetase DY252_RS17770 ENOG4105K8R UPF0145 protein DY252_RS17775 ENOG41083I7 UPF0145 protein DY252_RS17790 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase DY252_RS17805 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein DY252_RS17810 ENOG4105DIQ Transcriptional regulator DY252_RS17815 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family DY252_RS17820 ENOG4108NDG TRAP dicarboxylate DY252_RS17830 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS17840 ENOG4105DC8 reductase DY252_RS17855 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) DY252_RS17865 ENOG4107TQK Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity) DY252_RS17875 ENOG4105D1U peptidase U62 modulator of DNA gyrase DY252_RS17895 ENOG4105C5W Aldolase DY252_RS17900 ENOG4105C5W Aldolase DY252_RS17905 ENOG4105DEF Extracellular solute-binding protein, family 5 DY252_RS17910 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS17915 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS17920 ENOG4105C3U ABC transporter DY252_RS17925 ENOG4108JQ7 (ABC) transporter DY252_RS17930 ENOG4105N14 lysine exporter protein LysE YggA DY252_RS17955 ENOG4105E98 transcriptional regulator DeoR family DY252_RS17970 ENOG4105S7S phosphonate abc transporter DY252_RS17980 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DY252_RS17995 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) DY252_RS18000 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) DY252_RS18015 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) DY252_RS18035 ENOG4105CMS peptidase U62, modulator of DNA gyrase DY252_RS18045 ENOG4105CBD Diacylglycerol kinase DY252_RS18055 ENOG4107R5M Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity) DY252_RS18065 ENOG4105BZ1 (ABC) transporter DY252_RS18080 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) DY252_RS18105 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DY252_RS18110 ENOG4105C12 Phosphoribosylglycinamide synthetase DY252_RS18115 ENOG4105E0A ABC, transporter DY252_RS18120 ENOG4105EHG Permease protein DY252_RS18135 ENOG4105CF7 AraC family transcriptional regulator DY252_RS18140 ENOG4105EMU Dehydrogenase DY252_RS18155 ENOG4108Z6B deaminase DY252_RS18160 ENOG4108Z86 Glutamine amidotransferase DY252_RS18170 ENOG4106H78 methyltransferase DY252_RS18195 ENOG4105FYV Amp nucleosidase DY252_RS18225 ENOG4108RMU ferritin dps family protein DY252_RS18235 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DY252_RS18240 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) DY252_RS18245 ENOG4105BZU Histidine kinase DY252_RS18250 ENOG4105CAS nag kinase DY252_RS18255 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) DY252_RS18260 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins DY252_RS18265 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) DY252_RS18270 ENOG41087PG RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) DY252_RS18275 ENOG4107M91 50S ribosomal protein l34 DY252_RS18285 ENOG4107QZV Type I secretion membrane fusion protein DY252_RS18295 ENOG4108JJA ABC, transporter DY252_RS18300 ENOG4105VEJ Heat shock protein DY252_RS18310 ENOG4108Z4X TRANSCRIPTIONal DY252_RS18325 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DY252_RS18395 ENOG4105BZU Histidine kinase DY252_RS18400 ENOG4105CJW magnesium transporter DY252_RS18405 ENOG4105C6K Malic enzyme DY252_RS18415 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) DY252_RS18420 ENOG4105BZU Histidine kinase DY252_RS18470 ENOG4105CI0 Citrate lyase DY252_RS18475 ENOG4108X0B nad(p)h dehydrogenase (quinone) DY252_RS18485 ENOG4105CIS alcohol dehydrogenase DY252_RS18490 ENOG4105KVH Transcriptional regulator DY252_RS18495 ENOG4105K5X acetyltransferase DY252_RS18500 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) DY252_RS18525 ENOG4105C26 Dehydrogenase DY252_RS18530 ENOG4105C8Y Acetylornithine aminotransferase DY252_RS18540 ENOG4108KJ1 Trap dicarboxylate transporter, dctp subunit DY252_RS18550 ENOG4108K1J Transporter DctQ DY252_RS18555 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS18575 ENOG4105ENR peptidase, M24 DY252_RS18580 ENOG4105E5N succinylglutamate desuccinylase aspartoacylase DY252_RS18585 ENOG4108RYR transcriptional regulator AsnC family DY252_RS18615 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DY252_RS18620 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS18630 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS18650 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator DY252_RS18655 ENOG4105CNN ABC, transporter DY252_RS18660 ENOG4105C2J ABC transporter DY252_RS18665 ENOG4105ETE Transcriptional regulator (LacI family DY252_RS18675 ENOG4105D3D Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity) DY252_RS18690 ENOG4105FKQ transcriptional regulator DY252_RS18705 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component DY252_RS18715 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS18750 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) DY252_RS18755 ENOG4105ETX regulatoR DY252_RS18760 ENOG4105GR3 Histidine kinase DY252_RS18770 ENOG4108IV0 ABC, transporter DY252_RS18790 ENOG4107XBN GntR Family Transcriptional Regulator DY252_RS18795 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DY252_RS18800 ENOG4108RXX maleylacetoacetate isomerase DY252_RS18810 ENOG4105F1J Homogentisate 1,2-dioxygenase DY252_RS18825 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS18835 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS18845 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DY252_RS18850 ENOG4105F7P transcriptional regulator AsnC family DY252_RS18855 ENOG4108IV0 ABC, transporter DY252_RS18860 ENOG4105C0Z ABC transporter DY252_RS18870 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS18885 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DY252_RS18900 ENOG4105C26 Dehydrogenase DY252_RS18915 ENOG4105ERH Fumarylacetoacetate hydrolase DY252_RS18930 ENOG4105CZE histidine utilization repressor DY252_RS18935 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) DY252_RS18940 ENOG4105CI2 imidazolone-5-propionate hydrolase DY252_RS18945 ENOG4105C84 Histidine ammonia-lyase DY252_RS18960 ENOG4105CH5 extracellular solute-binding protein, family 7 DY252_RS18970 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS18980 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS19015 ENOG4105E9F Enoyl-CoA hydratase DY252_RS19020 ENOG4108ERU trap dicarboxylate transporter subunit DctP DY252_RS19080 ENOG4105F2I Transposase DY252_RS19085 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS19110 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS19125 ENOG4105CSU acyl-Coa dehydrogenase DY252_RS19130 ENOG4105CMG Carbohydrate kinase DY252_RS19135 ENOG41061GT Aldolase DY252_RS19145 ENOG4108FN7 Aldo keto reductase DY252_RS19150 ENOG4105DKT Transcriptional regulator DY252_RS19155 ENOG4105CNN ABC, transporter DY252_RS19170 ENOG4105BZU Histidine kinase DY252_RS19175 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DY252_RS19190 ENOG4105C32 Amino acid ABC transporter (Permease) DY252_RS19200 ENOG4105C2J ABC transporter DY252_RS19205 ENOG4108IV0 ABC, transporter DY252_RS19210 ENOG4105C0A alcohol dehydrogenase DY252_RS19215 ENOG4105C26 Dehydrogenase DY252_RS19220 ENOG4105C0A alcohol dehydrogenase DY252_RS19225 ENOG4105CPC Aldo Keto reductase DY252_RS19235 ENOG4105CMT Dihydroxyacetone kinase DY252_RS19240 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane DY252_RS19245 ENOG4105C2J ABC transporter DY252_RS19255 ENOG4105CNN ABC, transporter DY252_RS19260 ENOG4105ETE Transcriptional regulator (LacI family DY252_RS19270 ENOG4108UM1 dedA family DY252_RS19275 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) DY252_RS19280 ENOG41063TF transcriptional regulator (AraC DY252_RS19295 ENOG4105KDC 50s ribosomal protein l28 DY252_RS19305 ENOG4105BZU Histidine kinase DY252_RS19310 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) DY252_RS19330 ENOG4105M85 Bola protein DY252_RS19335 ENOG4105DKB L-sorbosone dehydrogenase DY252_RS19360 ENOG4108JU6 CBS domain protein DY252_RS19365 ENOG4105D49 3-dehydroquinate synthase DY252_RS19370 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) DY252_RS19380 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DY252_RS19385 ENOG4105BZU Histidine kinase DY252_RS19400 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate DY252_RS19420 ENOG4105C7R Atpase associated with various cellular activities aaa_3 DY252_RS19440 ENOG4105JQN Transcriptional regulator DY252_RS19445 ENOG4105CHF Glutathione S-transferase DY252_RS19450 ENOG4108505 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DY252_RS19455 ENOG4108VHN F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DY252_RS19460 ENOG4107Q7J ATP synthase subunit C DY252_RS19465 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) DY252_RS19470 ENOG4107PQ6 Inherit from NOG: atp synthase DY252_RS19480 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) DY252_RS19495 ENOG4105CEN a g-specific adenine glycosylase DY252_RS19515 ENOG4108JQ9 ABC transporter DY252_RS19520 ENOG41083U2 ABC transporter, permease DY252_RS19530 ENOG4105DZC cytosine deaminase DY252_RS19535 ENOG4107XWI flavin reductase domain protein, FMN-binding DY252_RS19545 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) DY252_RS19555 ENOG4108IYU L-aspartate oxidase DY252_RS19570 ENOG4105RK9 auxin efflux carrier DY252_RS19575 ENOG4108JJ7 ABC transporter DY252_RS19580 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) DY252_RS19585 ENOG4107WK2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) DY252_RS19595 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) DY252_RS19600 ENOG4105C8Q Methyl-accepting chemotaxis DY252_RS19610 ENOG4105E98 transcriptional regulator DeoR family DY252_RS19615 ENOG4105C8Y Acetylornithine aminotransferase DY252_RS19625 ENOG4105CHR reductase DY252_RS19630 ENOG4105NAE bifunctional deaminase-reductase domain protein DY252_RS19635 ENOG4105EJQ L-serine dehydratase DY252_RS19640 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DY252_RS19645 ENOG41063SB peptidase DY252_RS19650 ENOG4105CN1 protease DY252_RS19660 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) DY252_RS19670 ENOG4107R6G Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity) DY252_RS19695 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) DY252_RS19705 ENOG4108VHC Short-chain dehydrogenase reductase Sdr DY252_RS19735 ENOG4105D6P C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity) DY252_RS19760 ENOG4105DS0 Transcriptional regulator, Crp Fnr family DY252_RS19765 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) DY252_RS19770 ENOG4107R03 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) DY252_RS19775 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY DY252_RS19780 ENOG4105K5M 30s ribosomal protein S16 DY252_RS19785 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DY252_RS19790 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) DY252_RS19795 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) DY252_RS19800 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DY252_RS19810 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) DY252_RS19815 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DY252_RS19820 ENOG4108KPJ rna polymerase sigma factor DY252_RS19825 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) DY252_RS19835 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DY252_RS19840 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DY252_RS19865 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) DY252_RS19870 ENOG4105CHR reductase DY252_RS19890 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) DY252_RS19895 ENOG410856B UPF0235 protein DY252_RS19905 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DY252_RS19910 ENOG4105ETE Transcriptional regulator (LacI family DY252_RS19925 ENOG4105BZS acriflavin resistance protein DY252_RS19930 ENOG4105ENT Efflux transporter rnd family, mfp subunit DY252_RS19950 ENOG4105CYW agmatinase DY252_RS19955 ENOG4105EVZ LysR family transcriptional regulator DY252_RS19970 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) DY252_RS19990 ENOG4105D6J arsenicaL-resistance protein DY252_RS20005 ENOG4105C9A Phoh family DY252_RS20010 ENOG41076HS cation diffusion facilitator family transporter DY252_RS20015 ENOG4105DA4 cytochrome c-type biogenesis protein DY252_RS20020 ENOG4106FI7 cytochrome c-type biogenesis protein DY252_RS20035 ENOG4107ZDE Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) DY252_RS20040 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) DY252_RS20045 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) DY252_RS20050 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) DY252_RS20055 ENOG4105E3N F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DY252_RS20060 ENOG4108K3A Glutathione S-transferase DY252_RS20075 ENOG4105C25 Primosomal protein n' DY252_RS20080 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DY252_RS20090 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DY252_RS20105 ENOG4108U78 Glutathione S-transferase DY252_RS20115 ENOG4105CFQ glutamine synthetase DY252_RS20125 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) DY252_RS20130 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DY252_RS20135 ENOG4108Z4K mutator MutT protein DY252_RS20140 ENOG4105CR4 methylisocitrate lyase DY252_RS20145 ENOG4105EGS Mechanosensitive ion channel DY252_RS20155 ENOG4105D6Z AFG1 family ATPase DY252_RS20160 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DY252_RS20165 ENOG4105CMV Succinyl-CoA synthetase subunit beta DY252_RS20175 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 DY252_RS20185 ENOG4107QN2 dihydrolipoyl dehydrogenase DY252_RS20190 ENOG4108Z5K methylglyoxal synthase DY252_RS20225 ENOG4105CT4 transporter DY252_RS20230 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DY252_RS20245 ENOG4105K6V RNA polymerase DY252_RS20250 ENOG4108NIX Factor ChrR DY252_RS20255 ENOG4105D6S protein involved in catabolism of external DNA DY252_RS20260 ENOG4108R99 pseudouridine synthase DY252_RS20280 ENOG4106TD9 Diguanylate cyclase DY252_RS20290 ENOG4105CBX hi0933 family DY252_RS20320 ENOG4107QP3 malate synthase g DY252_RS20325 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) DY252_RS20330 ENOG4105BZU Histidine kinase DY252_RS20335 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha DY252_RS20340 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta DY252_RS20345 ENOG4108M0I Transcriptional regulator DY252_RS20350 ENOG4105EN6 Membrane DY252_RS20380 ENOG4105ENV phosphonate C-P lyase system protein PhnK DY252_RS20385 ENOG4105HRV phosphonate c-p lyase system protein phnl DY252_RS20390 ENOG4105FD8 phosphonate metabolism protein PhnM DY252_RS20395 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) DY252_RS20400 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) DY252_RS20415 ENOG4105EHI Phosphonate ABC transporter, periplasmic DY252_RS20420 ENOG4105D5T phosphonate abc transporter DY252_RS20425 ENOG4105DG4 malate L-lactate dehydrogenase DY252_RS20435 ENOG4105C94 Transporter DY252_RS20450 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component DY252_RS20455 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DY252_RS20475 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) DY252_RS20480 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme DY252_RS20485 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS20490 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) DY252_RS20495 ENOG4105DVW rieske (2Fe-2S) DY252_RS20500 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DY252_RS20505 ENOG4105ECQ AraC Family Transcriptional Regulator DY252_RS20510 ENOG4105BZJ Electron transfer flavoprotein DY252_RS20515 ENOG4105C10 Electron transfer flavoprotein DY252_RS20520 ENOG4105CIY formyltetrahydrofolate deformylase DY252_RS20530 ENOG4107WCI zn-dependent hydrolase of the beta-lactamase fold-like protein DY252_RS20640 ENOG4105D5G Transposase DY252_RS20645 ENOG4105C59 p-type ATPase DY252_RS20650 ENOG4105KTU Transcriptional regulator, arsr family DY252_RS20685 ENOG4105DXI Major Facilitator superfamily DY252_RS20690 ENOG4105VPX protein, conserved in bacteria DY252_RS20695 ENOG4105EHV domain protein DY252_RS20710 ENOG4105D5G Transposase DY252_RS20715 ENOG4105PGM cation diffusion facilitator family transporter DY252_RS20725 ENOG4105DND Transcriptional regulator DY252_RS20815 ENOG4105ENT Efflux transporter rnd family, mfp subunit DY252_RS20830 ENOG41061A5 transposase DY252_RS20865 ENOG4105E4C Lytic transglycosylase catalytic DY252_RS20890 ENOG4107SKI cobyrinic Acid a,c-diamide synthase DY252_RS20950 ENOG4105CPC Aldo Keto reductase DY252_RS21010 ENOG4105J7D transcriptional regulator DY252_RS21020 ENOG4105W5Q DNA repair protein (RadC DY252_RS21085 ENOG4108KU3 Integrase DY252_RS21105 ENOG4105C0D helicase DY252_RS21210 ENOG4105CAF HipA N-terminal domain protein DY252_RS21275 ENOG4107T6V glycerophosphoryl diester phosphodiesterase DY252_RS21280 ENOG4107QI1 Mate efflux family protein DY252_RS21295 ENOG4105KJF protein tyrosine phosphatase DY252_RS21310 ENOG4105EUJ GTP cyclohydrolase i DY252_RS21315 ENOG4105NWN ApaG protein DY252_RS21335 ENOG4105CUX Signal transduction histidine kinase DY252_RS21340 ENOG4108R3E Dna-3-methyladenine glycosylase i DY252_RS21350 ENOG4108RZE Tetr family transcriptional regulator DY252_RS21355 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) DY252_RS21360 ENOG4105BZU Histidine kinase DY252_RS21365 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) DY252_RS21375 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) DY252_RS21400 ENOG4105DKB L-sorbosone dehydrogenase DY252_RS21405 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) DY252_RS21415 ENOG4105C8Q Methyl-accepting chemotaxis DY252_RS21425 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) DY252_RS21435 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase DY252_RS21440 ENOG4105EYW Ion transport protein DY252_RS21445 ENOG4105CRQ synthase (Component I) DY252_RS21455 ENOG4105VDW Csbd family DY252_RS21470 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase DY252_RS21480 ENOG4105BZU Histidine kinase DY252_RS21490 ENOG4105DMJ Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity) DY252_RS21495 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) DY252_RS21510 ENOG4108RXX maleylacetoacetate isomerase DY252_RS21530 ENOG4105E09 nadh pyrophosphatase DY252_RS21540 ENOG4107QMP dna polymerase iii subunits gamma and tau DY252_RS21545 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) DY252_RS21550 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) DY252_RS21555 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) DY252_RS21560 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase DY252_RS21565 ENOG4108PVQ transcriptional regulator DY252_RS21575 ENOG4105CG6 trap dicarboxylate transporter dctm subunit DY252_RS21585 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit DY252_RS21590 ENOG4107RYR Transcriptional regulator, Crp Fnr family DY252_RS21595 ENOG4105F8J Adenylate Guanylate cyclase DY252_RS21625 ENOG4105I8F Histidine kinase DY252_RS21630 ENOG4105DCI Phosphohydrolase DY252_RS21650 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) DY252_RS21655 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DY252_RS21660 ENOG41080Z8 PHOSPHOCARRIER protein DY252_RS21665 ENOG4105DAS pts system DY252_RS21670 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) DY252_RS21675 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) DY252_RS21680 ENOG4105EB3 Histidine kinase DY252_RS21685 ENOG4105E3W Two component transcriptional regulator (Winged helix family DY252_RS21700 ENOG4105H1G trap transporter solute receptor taxi family DY252_RS21730 ENOG4105HEI LysR family (Transcriptional regulator DY252_RS21740 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) DY252_RS21750 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DY252_RS21760 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DY252_RS21765 ENOG4105EJC lysr family transcriptional regulator DY252_RS21790 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DY252_RS21795 ENOG410642W LysR family Transcriptional regulator DY252_RS21805 ENOG4105CHR reductase DY252_RS21810 ENOG4105K56 Transcriptional regulator DY252_RS21820 ENOG4105CHH sulfate transporter DY252_RS21845 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DY252_RS21850 ENOG4105DBV ornithine carbamoyltransferase DY252_RS21855 ENOG4105C8Y Acetylornithine aminotransferase DY252_RS21860 ENOG4105E3A (ABC) transporter DY252_RS21865 ENOG4105GB5 regulatory protein RecX DY252_RS21870 ENOG4105K89 arsenate reductase DY252_RS21885 ENOG41067MG lrgb family DY252_RS21905 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) DY252_RS21910 ENOG4105CDH Citrulline--aspartate ligase DY252_RS21920 ENOG410829K Lysine exporter protein (Lyse ygga) DY252_RS21925 ENOG4105DDW LysR family Transcriptional regulator DY252_RS21930 ENOG4105JN3 extra-cytoplasmic solute receptor family protein DY252_RS21945 ENOG4105CWC Acetylornithine deacetylase DY252_RS21960 ENOG4108JQC penicillin-binding protein 1A DY252_RS21965 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase DY252_RS22165 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)