locus-tag	class	description
FNC98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNC98_RS00020	COG0187	DNA topoisomerase II activity
FNC98_RS00025	COG0752	glycyl-tRNA synthetase alpha subunit
FNC98_RS00030	COG0751	glycine-tRNA ligase activity
FNC98_RS00040	COG0741	lytic transglycosylase activity
FNC98_RS00045	COG0006	proline dipeptidase activity
FNC98_RS00050	COG1739	Uncharacterized protein family UPF0029
FNC98_RS00055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNC98_RS00060	COG0569	domain protein
FNC98_RS00065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNC98_RS00065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNC98_RS00080	COG1652	LysM domain
FNC98_RS00085	COG0758	DNA mediated transformation
FNC98_RS00090	COG2922	Belongs to the Smg family
FNC98_RS00095	COG0551	DNA topoisomerase type I activity
FNC98_RS00110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FNC98_RS00120	COG0408	coproporphyrinogen oxidase activity
FNC98_RS00135	COG0463	Glycosyl transferase, family 2
FNC98_RS00140	COG3047	cAMP biosynthetic process
FNC98_RS00155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNC98_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS00205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNC98_RS00225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNC98_RS00230	COG0433	COG0433 Predicted ATPase
FNC98_RS00240	COG3078	GTPase activator activity
FNC98_RS00250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNC98_RS00255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNC98_RS00280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FNC98_RS00285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNC98_RS00305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNC98_RS00305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNC98_RS00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNC98_RS00335	COG0742	ribosomal rna small subunit methyltransferase
FNC98_RS00345	COG0402	S-adenosylhomocysteine deaminase activity
FNC98_RS00360	COG0678	peroxiredoxin activity
FNC98_RS00365	COG1528	Iron-storage protein
FNC98_RS00370	COG2081	HI0933 family
FNC98_RS00435	COG0697	spore germination
FNC98_RS00445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNC98_RS00445	COG0678	peroxiredoxin activity
FNC98_RS00475	COG0542	response to heat
FNC98_RS00485	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNC98_RS00485	COG3608	succinylglutamate desuccinylase aspartoacylase
FNC98_RS00495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNC98_RS00500	COG1349	DNA-binding transcription factor activity
FNC98_RS00530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FNC98_RS00550	COG0629	single-stranded DNA binding
FNC98_RS00560	COG5002	protein histidine kinase activity
FNC98_RS00565	COG2204	response regulator
FNC98_RS00570	COG3267	Type II secretory pathway component ExeA
FNC98_RS00570	COG3409	Peptidoglycan-binding domain 1 protein
FNC98_RS00580	COG0489	protein tyrosine kinase activity
FNC98_RS00595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNC98_RS00600	COG0726	polysaccharide deacetylase
FNC98_RS00610	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS00620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNC98_RS00635	COG0297	glycogen (starch) synthase activity
FNC98_RS00635	COG0438	transferase activity, transferring glycosyl groups
FNC98_RS00640	COG0726	polysaccharide deacetylase
FNC98_RS00670	COG0438	transferase activity, transferring glycosyl groups
FNC98_RS00705	COG2861	carbohydrate metabolic process
FNC98_RS00710	COG4942	peptidase
FNC98_RS00715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNC98_RS00720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNC98_RS00730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FNC98_RS00735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNC98_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNC98_RS00760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNC98_RS00765	COG2267	carboxylic ester hydrolase activity
FNC98_RS00770	COG2205	protein histidine kinase activity
FNC98_RS00775	COG0745	RESPONSE REGULATOR receiver
FNC98_RS00780	COG3678	ATP-independent chaperone mediated protein folding
FNC98_RS00800	COG1929	Belongs to the glycerate kinase type-1 family
FNC98_RS00805	COG2183	response to ionizing radiation
FNC98_RS00810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNC98_RS00830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNC98_RS00835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FNC98_RS00840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNC98_RS00845	COG3031	protein transport across the cell outer membrane
FNC98_RS00855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FNC98_RS00860	COG1459	type II secretion system
FNC98_RS00865	COG2165	general secretion pathway protein
FNC98_RS00875	COG2165	general secretion pathway protein
FNC98_RS00880	COG4795	General secretion pathway protein
FNC98_RS00885	COG3156	type II secretion system protein K
FNC98_RS00895	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FNC98_RS00905	COG0584	glycerophosphoryl diester phosphodiesterase
FNC98_RS00910	COG0688	phosphatidylethanolamine metabolic process
FNC98_RS00920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FNC98_RS00930	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNC98_RS00935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNC98_RS00935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNC98_RS00940	COG0802	atpase or kinase
FNC98_RS00955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNC98_RS00960	COG1923	regulation of RNA biosynthetic process
FNC98_RS00965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNC98_RS00970	COG0330	HflC and HflK could
FNC98_RS00975	COG0330	HflC and HflK could
FNC98_RS00980	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FNC98_RS00985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNC98_RS00995	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FNC98_RS01005	COG0281	malic enzyme
FNC98_RS01010	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FNC98_RS01015	COG0626	cystathionine gamma-synthase activity
FNC98_RS01020	COG0460	homoserine dehydrogenase
FNC98_RS01020	COG0527	aspartate kinase activity
FNC98_RS01040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNC98_RS01050	COG0137	argininosuccinate synthase activity
FNC98_RS01060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNC98_RS01090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNC98_RS01095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNC98_RS01100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FNC98_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
FNC98_RS01135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNC98_RS01140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNC98_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
FNC98_RS01175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNC98_RS01200	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNC98_RS01210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNC98_RS01225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNC98_RS01235	COG1404	Belongs to the peptidase S8 family
FNC98_RS01240	COG2315	Protein conserved in bacteria
FNC98_RS01245	COG1476	TRANSCRIPTIONal
FNC98_RS01270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNC98_RS01270	COG1648	precorrin-2 dehydrogenase activity
FNC98_RS01275	COG2264	protein methyltransferase activity
FNC98_RS01285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FNC98_RS01290	COG0138	bifunctional purine biosynthesis protein purh
FNC98_RS01300	COG0151	Belongs to the GarS family
FNC98_RS01305	COG0724	RNA recognition motif
FNC98_RS01345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNC98_RS01350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNC98_RS01355	COG0531	amino acid
FNC98_RS01370	COG2235	arginine
FNC98_RS01410	COG2814	Major facilitator Superfamily
FNC98_RS01420	COG1131	(ABC) transporter
FNC98_RS01425	COG0842	Transport permease protein
FNC98_RS01430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNC98_RS01435	COG0076	glutamate decarboxylase activity
FNC98_RS01440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNC98_RS01445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNC98_RS01450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNC98_RS01465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNC98_RS01470	COG1489	DNA binding
FNC98_RS01490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNC98_RS01500	COG2201	protein-glutamate methylesterase activity
FNC98_RS01505	COG1116	anion transmembrane transporter activity
FNC98_RS01505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNC98_RS01510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNC98_RS01515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNC98_RS01520	COG1116	anion transmembrane transporter activity
FNC98_RS01530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNC98_RS01540	COG0243	molybdopterin cofactor binding
FNC98_RS01545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNC98_RS01545	COG1648	precorrin-2 dehydrogenase activity
FNC98_RS01565	COG1643	Atp-dependent helicase
FNC98_RS01570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNC98_RS01575	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS01580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNC98_RS01585	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS01590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNC98_RS01595	COG0540	Belongs to the ATCase OTCase family
FNC98_RS01600	COG1981	membrane
FNC98_RS01615	COG0316	Belongs to the HesB IscA family
FNC98_RS01635	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FNC98_RS01650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNC98_RS01655	COG0254	rRNA binding
FNC98_RS01660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNC98_RS01670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FNC98_RS01675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNC98_RS01685	COG2832	Protein of unknown function (DUF454)
FNC98_RS01690	COG1595	DNA-templated transcription, initiation
FNC98_RS01705	COG2766	serine protein kinase
FNC98_RS01710	COG2718	Belongs to the UPF0229 family
FNC98_RS01715	COG2719	SpoVR family
FNC98_RS01725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNC98_RS01735	COG0735	belongs to the Fur family
FNC98_RS01745	COG2207	Transcriptional regulator
FNC98_RS01750	COG0673	inositol 2-dehydrogenase activity
FNC98_RS01785	COG0431	NADPH-dependent FMN reductase
FNC98_RS01790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNC98_RS01805	COG1842	Phage shock protein A
FNC98_RS01830	COG1609	Transcriptional regulator
FNC98_RS01845	COG3119	arylsulfatase activity
FNC98_RS01850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNC98_RS01865	COG0589	response to stress
FNC98_RS01880	COG1320	monovalent cation:proton antiporter activity
FNC98_RS01890	COG1006	Multisubunit Na H antiporter MnhC subunit
FNC98_RS01895	COG0651	ATP synthesis coupled electron transport
FNC98_RS01900	COG0651	ATP synthesis coupled electron transport
FNC98_RS01910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNC98_RS01910	COG2111	Na H antiporter
FNC98_RS01930	COG3250	beta-galactosidase activity
FNC98_RS01955	COG0604	alcohol dehydrogenase
FNC98_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS01970	COG0457	Tetratricopeptide repeat
FNC98_RS01975	COG0583	DNA-binding transcription factor activity
FNC98_RS01980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNC98_RS01985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNC98_RS01990	COG3250	beta-galactosidase activity
FNC98_RS01995	COG3710	Transcriptional regulator
FNC98_RS02040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNC98_RS02045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNC98_RS02050	COG0175	sulfate reduction
FNC98_RS02055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNC98_RS02060	COG1278	Cold shock
FNC98_RS02070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNC98_RS02075	COG1024	Enoyl-CoA hydratase
FNC98_RS02075	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNC98_RS02080	COG0183	Belongs to the thiolase family
FNC98_RS02125	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FNC98_RS02135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNC98_RS02140	COG0163	prenyltransferase activity
FNC98_RS02145	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS02145	COG4946	Tricorn protease homolog
FNC98_RS02145	COG1506	peptidase
FNC98_RS02155	COG4774	siderophore transport
FNC98_RS02165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNC98_RS02185	COG4942	peptidase
FNC98_RS02190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNC98_RS02210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNC98_RS02215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNC98_RS02240	COG1301	dicarboxylic acid transport
FNC98_RS02245	COG1671	Belongs to the UPF0178 family
FNC98_RS02265	COG0557	exoribonuclease II activity
FNC98_RS02270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNC98_RS02300	COG0360	Binds together with S18 to 16S ribosomal RNA
FNC98_RS02305	COG2965	DNA replication, synthesis of RNA primer
FNC98_RS02310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNC98_RS02315	COG0359	binds to the 23S rRNA
FNC98_RS02325	COG1077	Cell shape determining protein MreB Mrl
FNC98_RS02330	COG1792	Involved in formation and maintenance of cell shape
FNC98_RS02335	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FNC98_RS02340	COG0424	maF-like protein
FNC98_RS02345	COG1530	ribonuclease E activity
FNC98_RS02360	COG0312	modulator of DNA gyrase
FNC98_RS02375	COG0312	modulator of DNA gyrase
FNC98_RS02385	COG2239	Acts as a magnesium transporter
FNC98_RS02390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNC98_RS02395	COG1660	Displays ATPase and GTPase activities
FNC98_RS02405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNC98_RS02410	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNC98_RS02415	COG1137	ATPase activity
FNC98_RS02430	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FNC98_RS02435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNC98_RS02435	COG0517	IMP dehydrogenase activity
FNC98_RS02450	COG1127	ABC transporter
FNC98_RS02455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNC98_RS02460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNC98_RS02465	COG2854	intermembrane phospholipid transfer
FNC98_RS02475	COG5007	Belongs to the BolA IbaG family
FNC98_RS02480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNC98_RS02485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNC98_RS02490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNC98_RS02500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FNC98_RS02505	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNC98_RS02510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNC98_RS02520	COG0723	plastoquinol--plastocyanin reductase activity
FNC98_RS02525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNC98_RS02530	COG2857	Cytochrome c1
FNC98_RS02535	COG0625	glutathione transferase activity
FNC98_RS02540	COG2969	positive regulation of protein catabolic process
FNC98_RS02545	COG2823	Periplasmic or secreted lipoprotein
FNC98_RS02550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FNC98_RS02560	COG3107	peptidoglycan biosynthetic process
FNC98_RS02565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNC98_RS02575	COG3850	Histidine kinase
FNC98_RS02575	COG4999	Histidine kinase
FNC98_RS02575	COG2205	protein histidine kinase activity
FNC98_RS02575	COG3437	response regulator, receiver
FNC98_RS02580	COG0166	Belongs to the GPI family
FNC98_RS02585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNC98_RS02590	COG2814	Major facilitator Superfamily
FNC98_RS02595	COG0477	Major facilitator Superfamily
FNC98_RS02600	COG2001	Belongs to the MraZ family
FNC98_RS02605	COG0275	rRNA processing
FNC98_RS02610	COG3116	cell division
FNC98_RS02615	COG0768	penicillin binding
FNC98_RS02620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNC98_RS02625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNC98_RS02630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNC98_RS02640	COG0772	Belongs to the SEDS family
FNC98_RS02650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNC98_RS02665	COG0849	cell division
FNC98_RS02670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNC98_RS02675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FNC98_RS02685	COG0739	heme binding
FNC98_RS02690	COG0653	protein targeting
FNC98_RS02695	COG0494	nUDIX hydrolase
FNC98_RS02705	COG0583	DNA-binding transcription factor activity
FNC98_RS02720	COG1368	sulfuric ester hydrolase activity
FNC98_RS02735	COG0237	dephospho-CoA kinase activity
FNC98_RS02740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FNC98_RS02745	COG1459	type II secretion system
FNC98_RS02750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FNC98_RS02780	COG2186	Transcriptional regulator
FNC98_RS02785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FNC98_RS02790	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNC98_RS02795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNC98_RS02805	COG1566	PFAM secretion protein HlyD family protein
FNC98_RS02810	COG0628	permease
FNC98_RS02820	COG1049	propionate catabolic process, 2-methylcitrate cycle
FNC98_RS02850	COG1505	serine-type exopeptidase activity
FNC98_RS02865	COG0004	ammonium transporteR
FNC98_RS02870	COG0105	UTP biosynthetic process
FNC98_RS02875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNC98_RS02885	COG1426	Protein conserved in bacteria
FNC98_RS02890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNC98_RS02895	COG0124	histidyl-tRNA synthetase
FNC98_RS02900	COG2976	Protein conserved in bacteria
FNC98_RS02905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNC98_RS02910	COG1160	GTP binding
FNC98_RS02915	COG1570	exodeoxyribonuclease VII activity
FNC98_RS02920	COG0516	GMP reductase activity
FNC98_RS02920	COG0517	IMP dehydrogenase activity
FNC98_RS02925	COG0519	Catalyzes the synthesis of GMP from XMP
FNC98_RS02925	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNC98_RS02975	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FNC98_RS02980	COG0400	carboxylic ester hydrolase activity
FNC98_RS02990	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS02990	COG1506	peptidase
FNC98_RS02990	COG4946	Tricorn protease homolog
FNC98_RS03010	COG0456	acetyltransferase
FNC98_RS03015	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FNC98_RS03035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNC98_RS03035	COG0047	phosphoribosylformylglycinamidine synthase activity
FNC98_RS03040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNC98_RS03045	COG0590	tRNA wobble adenosine to inosine editing
FNC98_RS03055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNC98_RS03060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNC98_RS03070	COG0762	integral membrane protein
FNC98_RS03075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNC98_RS03080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNC98_RS03095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNC98_RS03100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FNC98_RS03105	COG0189	ligase activity
FNC98_RS03115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNC98_RS03145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNC98_RS03150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNC98_RS03165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNC98_RS03180	COG3079	Belongs to the UPF0149 family
FNC98_RS03185	COG0006	proline dipeptidase activity
FNC98_RS03190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNC98_RS03195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNC98_RS03200	COG0302	gtp cyclohydrolase
FNC98_RS03210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNC98_RS03220	COG0297	glycogen (starch) synthase activity
FNC98_RS03225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNC98_RS03235	COG2205	protein histidine kinase activity
FNC98_RS03240	COG0745	RESPONSE REGULATOR receiver
FNC98_RS03290	COG1472	Belongs to the glycosyl hydrolase 3 family
FNC98_RS03340	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FNC98_RS03345	COG3118	belongs to the thioredoxin family
FNC98_RS03350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNC98_RS03360	COG3130	regulation of translation
FNC98_RS03365	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FNC98_RS03380	COG0314	molybdopterin synthase activity
FNC98_RS03385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FNC98_RS03390	COG0315	cyclic pyranopterin monophosphate synthase activity
FNC98_RS03395	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNC98_RS03410	COG0303	'Molybdopterin
FNC98_RS03420	COG3005	denitrification pathway
FNC98_RS03425	COG3043	anaerobic respiration
FNC98_RS03430	COG0243	molybdopterin cofactor binding
FNC98_RS03440	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNC98_RS03440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNC98_RS03445	COG4459	periplasmic nitrate reductase
FNC98_RS03450	COG1444	tRNA N-acetyltransferase activity
FNC98_RS03455	COG1131	(ABC) transporter
FNC98_RS03465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNC98_RS03470	COG1272	protein, Hemolysin III
FNC98_RS03480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNC98_RS03485	COG3022	response to hydroperoxide
FNC98_RS03490	COG0513	Belongs to the DEAD box helicase family
FNC98_RS03515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNC98_RS03520	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNC98_RS03540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FNC98_RS03550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNC98_RS03560	COG1666	GTP binding
FNC98_RS03565	COG0457	Tetratricopeptide repeat
FNC98_RS03580	COG0733	neurotransmitter:sodium symporter activity
FNC98_RS03585	COG0564	pseudouridine synthase activity
FNC98_RS03590	COG2918	glutathione biosynthetic process
FNC98_RS03595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNC98_RS03595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNC98_RS03625	COG4536	flavin adenine dinucleotide binding
FNC98_RS03630	COG4137	Cytochrome C assembly protein
FNC98_RS03635	COG0701	Predicted permease
FNC98_RS03640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNC98_RS03655	COG0697	spore germination
FNC98_RS03660	COG0228	four-way junction DNA binding
FNC98_RS03665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNC98_RS03675	COG0335	large ribosomal subunit rRNA binding
FNC98_RS03680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNC98_RS03685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNC98_RS03690	COG1605	Chorismate mutase
FNC98_RS03690	COG0287	Prephenate dehydrogenase
FNC98_RS03695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNC98_RS03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS03730	COG0612	Peptidase, M16
FNC98_RS03740	COG0077	Prephenate dehydratase
FNC98_RS03740	COG1605	Chorismate mutase
FNC98_RS03745	COG3122	Protein conserved in bacteria
FNC98_RS03755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNC98_RS03765	COG0564	pseudouridine synthase activity
FNC98_RS03785	COG2226	methyltransferase
FNC98_RS03790	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNC98_RS03795	COG0023	Translation Initiation Factor
FNC98_RS03815	COG0259	pyridoxamine-phosphate oxidase activity
FNC98_RS03825	COG2326	polyphosphate kinase activity
FNC98_RS03830	COG0494	nUDIX hydrolase
FNC98_RS03835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNC98_RS03840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNC98_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS03850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNC98_RS03855	COG2610	gluconate transmembrane transporter activity
FNC98_RS03875	COG0745	RESPONSE REGULATOR receiver
FNC98_RS03880	COG0848	biopolymer transport protein
FNC98_RS03900	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FNC98_RS03910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNC98_RS03915	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNC98_RS03920	COG4133	protoheme IX ABC transporter activity
FNC98_RS03950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNC98_RS03965	COG0659	secondary active sulfate transmembrane transporter activity
FNC98_RS03975	COG3313	Fe-S protein
FNC98_RS03990	COG0587	DNA-directed DNA polymerase activity
FNC98_RS04000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNC98_RS04020	COG1823	symporter activity
FNC98_RS04025	COG3706	GGDEF domain
FNC98_RS04025	COG5001	Diguanylate cyclase
FNC98_RS04025	COG4251	negative regulation of phosphorylation
FNC98_RS04025	COG2203	Gaf domain
FNC98_RS04045	COG2205	protein histidine kinase activity
FNC98_RS04045	COG2198	Histidine kinase
FNC98_RS04045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNC98_RS04045	COG0784	Response regulator, receiver
FNC98_RS04080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNC98_RS04090	COG0330	HflC and HflK could
FNC98_RS04115	COG0114	fumarate hydratase activity
FNC98_RS04130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNC98_RS04135	COG2867	negative regulation of translational initiation
FNC98_RS04140	COG2914	Belongs to the UPF0125 (RnfH) family
FNC98_RS04165	COG4172	Belongs to the ABC transporter superfamily
FNC98_RS04170	COG4171	peptide transport system, permease
FNC98_RS04180	COG0747	negative chemotaxis
FNC98_RS04185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FNC98_RS04190	COG1842	Phage shock protein A
FNC98_RS04205	COG3106	COG3106 Predicted ATPase
FNC98_RS04210	COG3768	UPF0283 membrane protein
FNC98_RS04220	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNC98_RS04235	COG0625	glutathione transferase activity
FNC98_RS04280	COG0811	peptide transport
FNC98_RS04285	COG0811	peptide transport
FNC98_RS04290	COG0848	biopolymer transport protein
FNC98_RS04305	COG0175	sulfate reduction
FNC98_RS04310	COG2895	sulfate adenylyltransferase (ATP) activity
FNC98_RS04315	COG0471	metal ion transport
FNC98_RS04315	COG3273	potassium ion transport
FNC98_RS04320	COG0529	Catalyzes the synthesis of activated sulfate
FNC98_RS04325	COG3590	peptidase
FNC98_RS04375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FNC98_RS04385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNC98_RS04390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNC98_RS04400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNC98_RS04455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNC98_RS04460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNC98_RS04490	COG1410	methionine synthase
FNC98_RS04490	COG0646	methionine synthase
FNC98_RS04495	COG4946	Tricorn protease homolog
FNC98_RS04495	COG0793	Belongs to the peptidase S41A family
FNC98_RS04500	COG2137	regulation of response to DNA damage stimulus
FNC98_RS04505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNC98_RS04510	COG0527	aspartate kinase activity
FNC98_RS04515	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FNC98_RS04545	COG5016	pyruvate
FNC98_RS04545	COG0511	ligase activity, forming carbon-carbon bonds
FNC98_RS04550	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FNC98_RS04570	COG0513	Belongs to the DEAD box helicase family
FNC98_RS04650	COG0271	Belongs to the BolA IbaG family
FNC98_RS04665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNC98_RS04670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNC98_RS04675	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNC98_RS04680	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNC98_RS04685	COG1805	sodium ion transport
FNC98_RS04690	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNC98_RS04695	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNC98_RS04700	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNC98_RS04705	COG2871	sodium ion transport
FNC98_RS04710	COG1477	protein flavinylation
FNC98_RS04715	COG2991	Protein conserved in bacteria
FNC98_RS04735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FNC98_RS04740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNC98_RS04755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FNC98_RS04760	COG0560	Phosphoserine phosphatase
FNC98_RS04770	COG0084	hydrolase, TatD family'
FNC98_RS04780	COG0018	arginyl-trna synthetase
FNC98_RS04785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNC98_RS04790	COG0456	acetyltransferase
FNC98_RS04805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNC98_RS04810	COG0343	queuine tRNA-ribosyltransferase activity
FNC98_RS04815	COG1862	Preprotein translocase
FNC98_RS04820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNC98_RS04825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNC98_RS04835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNC98_RS04835	COG1648	precorrin-2 dehydrogenase activity
FNC98_RS04855	COG1045	serine acetyltransferase
FNC98_RS04865	COG1104	cysteine desulfurase activity
FNC98_RS04870	COG0822	iron-sulfur transferase activity
FNC98_RS04885	COG0443	Heat shock 70 kDa protein
FNC98_RS04895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNC98_RS04900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNC98_RS04905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNC98_RS04905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNC98_RS04925	COG2354	Protein conserved in bacteria
FNC98_RS04930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNC98_RS04935	COG0142	geranyltranstransferase activity
FNC98_RS04940	COG1722	exodeoxyribonuclease VII activity
FNC98_RS04945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNC98_RS04945	COG0301	tRNA thio-modification
FNC98_RS04980	COG0745	RESPONSE REGULATOR receiver
FNC98_RS04990	COG5507	3-demethylubiquinone-9 3-methyltransferase
FNC98_RS04995	COG1950	PFAM Membrane protein of
FNC98_RS05000	COG2974	May be involved in recombination
FNC98_RS05005	COG1404	Belongs to the peptidase S8 family
FNC98_RS05010	COG2205	protein histidine kinase activity
FNC98_RS05045	COG0488	(ABC) transporter
FNC98_RS05050	COG0784	Response regulator, receiver
FNC98_RS05050	COG2205	protein histidine kinase activity
FNC98_RS05070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNC98_RS05075	COG0339	signal peptide processing
FNC98_RS05085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNC98_RS05090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNC98_RS05095	COG1609	Transcriptional regulator
FNC98_RS05100	COG1085	galactose-1-phosphate uridylyltransferase
FNC98_RS05105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNC98_RS05110	COG1802	Transcriptional regulator
FNC98_RS05125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNC98_RS05135	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNC98_RS05140	COG0573	inorganic phosphate transmembrane transporter activity
FNC98_RS05145	COG0573	inorganic phosphate transmembrane transporter activity
FNC98_RS05150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNC98_RS05155	COG0704	Plays a role in the regulation of phosphate uptake
FNC98_RS05160	COG1392	Phosphate transport regulator
FNC98_RS05165	COG0306	phosphate transporter
FNC98_RS05175	COG0583	DNA-binding transcription factor activity
FNC98_RS05205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNC98_RS05210	COG0497	DNA recombination
FNC98_RS05215	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNC98_RS05230	COG4770	biotin carboxylase activity
FNC98_RS05240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNC98_RS05245	COG1960	acyl-CoA dehydrogenase activity
FNC98_RS05250	COG0789	Transcriptional regulator
FNC98_RS05260	COG1960	acyl-CoA dehydrogenase activity
FNC98_RS05265	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNC98_RS05265	COG1024	Enoyl-CoA hydratase
FNC98_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS05315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNC98_RS05320	COG0826	peptidase U32
FNC98_RS05340	COG3250	beta-galactosidase activity
FNC98_RS05355	COG0640	Transcriptional regulator
FNC98_RS05360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS05365	COG1566	PFAM secretion protein HlyD family protein
FNC98_RS05380	COG1592	Rubrerythrin
FNC98_RS05385	COG2062	phosphohistidine phosphatase, SixA
FNC98_RS05390	COG2840	Smr protein MutS2
FNC98_RS05395	COG2890	protein-(glutamine-N5) methyltransferase activity
FNC98_RS05400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNC98_RS05405	COG2814	Major facilitator Superfamily
FNC98_RS05410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNC98_RS05415	COG0321	lipoyl(octanoyl) transferase activity
FNC98_RS05420	COG2921	Belongs to the UPF0250 family
FNC98_RS05430	COG1686	Belongs to the peptidase S11 family
FNC98_RS05435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNC98_RS05440	COG0772	Belongs to the SEDS family
FNC98_RS05445	COG0768	penicillin binding
FNC98_RS05450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNC98_RS05460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNC98_RS05470	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FNC98_RS05475	COG0495	leucyl-tRNA aminoacylation
FNC98_RS05480	COG2888	peptidyl-tyrosine sulfation
FNC98_RS05485	COG1067	ATP-dependent peptidase activity
FNC98_RS05510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNC98_RS05515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNC98_RS05520	COG0649	NAD binding
FNC98_RS05520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNC98_RS05540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNC98_RS05545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNC98_RS05550	COG0839	Belongs to the complex I subunit 6 family
FNC98_RS05555	COG0713	ATP synthesis coupled electron transport
FNC98_RS05565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNC98_RS05585	COG0513	Belongs to the DEAD box helicase family
FNC98_RS05605	COG0288	reversible hydration of carbon dioxide
FNC98_RS05610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNC98_RS05630	COG0159	tryptophan synthase activity
FNC98_RS05640	COG0134	indole-3-glycerol-phosphate synthase activity
FNC98_RS05640	COG0135	phosphoribosylanthranilate isomerase activity
FNC98_RS05655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNC98_RS05665	COG0009	L-threonylcarbamoyladenylate synthase
FNC98_RS05675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNC98_RS05680	COG1187	pseudouridine synthase activity
FNC98_RS05705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNC98_RS05715	COG3108	Peptidase M15
FNC98_RS05725	COG4771	TonB-dependent receptor
FNC98_RS05735	COG4771	TonB-dependent receptor
FNC98_RS05755	COG1858	cytochrome C peroxidase
FNC98_RS05770	COG0440	acetolactate synthase activity
FNC98_RS05775	COG0028	Belongs to the TPP enzyme family
FNC98_RS05780	COG3724	N-succinylarginine dihydrolase activity
FNC98_RS05785	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FNC98_RS05790	COG4206	TonB-dependent receptor
FNC98_RS05795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNC98_RS05805	COG1492	cobalamin metabolic process
FNC98_RS05810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNC98_RS05825	COG0436	Aminotransferase
FNC98_RS05840	COG1454	alcohol dehydrogenase
FNC98_RS05850	COG0442	prolyl-tRNA aminoacylation
FNC98_RS05860	COG1054	Belongs to the UPF0176 family
FNC98_RS05870	COG1234	tRNA 3'-trailer cleavage
FNC98_RS05880	COG1720	tRNA m6t6A37 methyltransferase activity
FNC98_RS05890	COG0784	Response regulator, receiver
FNC98_RS05890	COG2205	protein histidine kinase activity
FNC98_RS05890	COG5002	protein histidine kinase activity
FNC98_RS05910	COG0346	lactoylglutathione lyase activity
FNC98_RS05915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNC98_RS05920	COG4660	Part of a membrane complex involved in electron transport
FNC98_RS05925	COG4659	FMN binding
FNC98_RS05930	COG4658	electron transport chain
FNC98_RS05935	COG4656	Part of a membrane complex involved in electron transport
FNC98_RS05945	COG4657	Part of a membrane complex involved in electron transport
FNC98_RS05955	COG2133	pyrroloquinoline quinone binding
FNC98_RS05965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FNC98_RS05975	COG1253	flavin adenine dinucleotide binding
FNC98_RS05980	COG0515	serine threonine protein kinase
FNC98_RS05995	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FNC98_RS06005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNC98_RS06015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNC98_RS06020	COG2226	methyltransferase
FNC98_RS06025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNC98_RS06030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNC98_RS06035	COG0632	four-way junction helicase activity
FNC98_RS06040	COG2255	four-way junction helicase activity
FNC98_RS06045	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FNC98_RS06055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FNC98_RS06075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNC98_RS06080	COG0326	Molecular chaperone. Has ATPase activity
FNC98_RS06090	COG1199	ATP-dependent helicase activity
FNC98_RS06105	COG2267	carboxylic ester hydrolase activity
FNC98_RS06110	COG0318	PFAM AMP-dependent synthetase and ligase
FNC98_RS06115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNC98_RS06125	COG2951	lytic endotransglycosylase activity
FNC98_RS06130	COG2983	Belongs to the UPF0260 family
FNC98_RS06135	COG3148	PFAM DTW domain containing protein
FNC98_RS06145	COG1077	Cell shape determining protein MreB Mrl
FNC98_RS06150	COG1228	amidohydrolase
FNC98_RS06160	COG0405	Gamma-glutamyltransferase
FNC98_RS06170	COG2153	protein acetylation
FNC98_RS06180	COG0107	imidazoleglycerol-phosphate synthase activity
FNC98_RS06190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNC98_RS06195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNC98_RS06195	COG0131	Imidazoleglycerol-phosphate dehydratase
FNC98_RS06205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNC98_RS06245	COG0824	Thioesterase
FNC98_RS06250	COG0811	peptide transport
FNC98_RS06260	COG3064	Membrane
FNC98_RS06265	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS06270	COG2885	chlorophyll binding
FNC98_RS06275	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FNC98_RS06300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNC98_RS06330	COG2205	protein histidine kinase activity
FNC98_RS06335	COG0745	RESPONSE REGULATOR receiver
FNC98_RS06345	COG0584	glycerophosphoryl diester phosphodiesterase
FNC98_RS06370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS06390	COG4771	TonB-dependent receptor
FNC98_RS06395	COG0457	Tetratricopeptide repeat
FNC98_RS06420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNC98_RS06435	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNC98_RS06490	COG1162	GTPase activity
FNC98_RS06500	COG1803	Methylglyoxal synthase
FNC98_RS06525	COG1714	RDD family
FNC98_RS06540	COG0733	neurotransmitter:sodium symporter activity
FNC98_RS06545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNC98_RS06550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNC98_RS06595	COG1309	transcriptional regulator
FNC98_RS06600	COG1472	Belongs to the glycosyl hydrolase 3 family
FNC98_RS06605	COG0471	metal ion transport
FNC98_RS06620	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNC98_RS06625	COG2186	Transcriptional regulator
FNC98_RS06630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FNC98_RS06635	COG0450	alkyl hydroperoxide reductase
FNC98_RS06650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNC98_RS06680	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FNC98_RS06685	COG1196	nuclear chromosome segregation
FNC98_RS06705	COG0702	epimerase
FNC98_RS06710	COG0583	DNA-binding transcription factor activity
FNC98_RS06725	COG1032	radical SAM domain protein
FNC98_RS06745	COG0405	Gamma-glutamyltransferase
FNC98_RS06765	COG1714	RDD family
FNC98_RS06795	COG0328	RNA-DNA hybrid ribonuclease activity
FNC98_RS06835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNC98_RS06855	COG0735	belongs to the Fur family
FNC98_RS06860	COG0716	FMN binding
FNC98_RS06875	COG0596	Alpha beta hydrolase
FNC98_RS06880	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FNC98_RS06885	COG0033	Phosphoglucomutase
FNC98_RS06890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNC98_RS06910	COG2988	succinylglutamate desuccinylase activity
FNC98_RS06920	COG0022	dehydrogenase e1 component
FNC98_RS06935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNC98_RS06935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNC98_RS06945	COG0717	Belongs to the dCTP deaminase family
FNC98_RS06995	COG4181	ATPase activity
FNC98_RS07000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FNC98_RS07005	COG1090	epimerase
FNC98_RS07010	COG0628	permease
FNC98_RS07020	COG2350	Protein conserved in bacteria
FNC98_RS07045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNC98_RS07050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNC98_RS07060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNC98_RS07075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNC98_RS07080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNC98_RS07085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNC98_RS07090	COG0539	negative regulation of cytoplasmic translation
FNC98_RS07095	COG0776	regulation of translation
FNC98_RS07105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FNC98_RS07110	COG0284	orotidine-5'-phosphate decarboxylase activity
FNC98_RS07115	COG1555	photosystem II stabilization
FNC98_RS07120	COG1530	ribonuclease E activity
FNC98_RS07125	COG0564	pseudouridine synthase activity
FNC98_RS07135	COG1399	metal-binding, possibly nucleic acid-binding protein
FNC98_RS07140	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNC98_RS07145	COG0416	fatty acid biosynthetic process
FNC98_RS07150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNC98_RS07155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNC98_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNC98_RS07170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNC98_RS07175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNC98_RS07180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNC98_RS07185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNC98_RS07200	COG0084	hydrolase, TatD family'
FNC98_RS07215	COG2304	oxidoreductase activity
FNC98_RS07235	COG0714	Associated with various cellular activities
FNC98_RS07250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FNC98_RS07255	COG0372	Belongs to the citrate synthase family
FNC98_RS07265	COG2828	Protein conserved in bacteria
FNC98_RS07275	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FNC98_RS07285	COG1956	GAF domain-containing protein
FNC98_RS07300	COG0793	Belongs to the peptidase S41A family
FNC98_RS07305	COG1757	Na H antiporter
FNC98_RS07310	COG0308	aminopeptidase N
FNC98_RS07325	COG4447	cellulose binding
FNC98_RS07330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS07335	COG2902	Dehydrogenase
FNC98_RS07340	COG0167	dihydroorotate dehydrogenase activity
FNC98_RS07365	COG0367	asparagine synthase
FNC98_RS07375	COG4555	ABC transporter
FNC98_RS07380	COG1668	transmembrane transport
FNC98_RS07385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNC98_RS07390	COG0072	phenylalanine-tRNA ligase activity
FNC98_RS07390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNC98_RS07395	COG0776	regulation of translation
FNC98_RS07415	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNC98_RS07415	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNC98_RS07420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNC98_RS07420	COG0493	'glutamate synthase
FNC98_RS07435	COG1280	lysine exporter protein (LysE YggA)
FNC98_RS07455	COG1595	DNA-templated transcription, initiation
FNC98_RS07490	COG2252	PERMEase
FNC98_RS07495	COG0037	tRNA processing
FNC98_RS07500	COG0589	response to stress
FNC98_RS07505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNC98_RS07520	COG2217	Heavy metal translocating P-type atpase
FNC98_RS07530	COG2010	Cytochrome c
FNC98_RS07545	COG3278	Belongs to the heme-copper respiratory oxidase family
FNC98_RS07585	COG0534	Mate efflux family protein
FNC98_RS07590	COG0556	nucleotide-excision repair
FNC98_RS07605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FNC98_RS07610	COG0602	queuosine metabolic process
FNC98_RS07615	COG1902	pentaerythritol trinitrate reductase activity
FNC98_RS07630	COG1199	ATP-dependent helicase activity
FNC98_RS07635	COG0417	DNA replication proofreading
FNC98_RS07640	COG0626	cystathionine gamma-synthase activity
FNC98_RS07650	COG4106	trans-aconitate 2-methyltransferase activity
FNC98_RS07655	COG0385	Bile acid
FNC98_RS07710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNC98_RS07715	COG1785	Belongs to the alkaline phosphatase family
FNC98_RS07720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FNC98_RS07725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNC98_RS07730	COG0572	uridine kinase
FNC98_RS07740	COG4771	TonB-dependent receptor
FNC98_RS07750	COG1858	cytochrome C peroxidase
FNC98_RS07765	COG0813	purine-nucleoside phosphorylase activity
FNC98_RS07770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FNC98_RS07780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNC98_RS07810	COG3040	lipid binding
FNC98_RS07835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNC98_RS07840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNC98_RS07845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FNC98_RS07850	COG0574	Belongs to the PEP-utilizing enzyme family
FNC98_RS07850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNC98_RS07855	COG0247	lactate metabolic process
FNC98_RS07855	COG0277	FAD linked oxidase domain protein
FNC98_RS07865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNC98_RS07880	COG2850	peptidyl-arginine hydroxylation
FNC98_RS07885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNC98_RS07895	COG0482	sulfurtransferase activity
FNC98_RS07905	COG1187	pseudouridine synthase activity
FNC98_RS07915	COG1278	Cold shock
FNC98_RS07925	COG0542	response to heat
FNC98_RS07930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNC98_RS07935	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FNC98_RS07945	COG0492	ferredoxin-NADP+ reductase activity
FNC98_RS07950	COG0686	Belongs to the AlaDH PNT family
FNC98_RS07960	COG1674	ftsk spoiiie
FNC98_RS07960	COG0531	amino acid
FNC98_RS07965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FNC98_RS07970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNC98_RS07975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNC98_RS07980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNC98_RS07990	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNC98_RS07995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNC98_RS08015	COG2866	Carboxypeptidase
FNC98_RS08020	COG1115	amino acid carrier protein
FNC98_RS08030	COG3139	Protein of unknown function (DUF1315)
FNC98_RS08090	COG2824	Alkylphosphonate utilization operon protein PhnA
FNC98_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNC98_RS08115	COG0252	asparaginase activity
FNC98_RS08120	COG0616	signal peptide processing
FNC98_RS08140	COG0778	Nitroreductase
FNC98_RS08145	COG0017	Asparaginyl-tRNA synthetase
FNC98_RS08150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNC98_RS08155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNC98_RS08160	COG0156	8-amino-7-oxononanoate synthase activity
FNC98_RS08165	COG2226	methyltransferase
FNC98_RS08170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNC98_RS08185	COG3340	Belongs to the peptidase S51 family
FNC98_RS08195	COG0596	Alpha beta hydrolase
FNC98_RS08200	COG2819	hydrolase of the alpha beta superfamily
FNC98_RS08225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNC98_RS08230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNC98_RS08250	COG3082	Protein of unknown function (DUF1414)
FNC98_RS08255	COG3081	Nucleoid-associated protein
FNC98_RS08260	COG0418	dihydroorotase activity
FNC98_RS08285	COG3008	intermembrane lipid transfer
FNC98_RS08290	COG2995	paraquat-inducible protein a
FNC98_RS08370	COG1401	restriction endodeoxyribonuclease activity
FNC98_RS08380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNC98_RS08395	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FNC98_RS08415	COG0519	Catalyzes the synthesis of GMP from XMP
FNC98_RS08420	COG0670	Belongs to the BI1 family
FNC98_RS08430	COG2923	Belongs to the DsrF TusC family
FNC98_RS08455	COG0501	Belongs to the peptidase M48B family
FNC98_RS08460	COG1704	LemA family
FNC98_RS08470	COG0800	Aldolase
FNC98_RS08485	COG0363	glucosamine-6-phosphate deaminase activity
FNC98_RS08490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNC98_RS08495	COG1737	Transcriptional regulator
FNC98_RS08500	COG0469	pyruvate kinase activity
FNC98_RS08505	COG0205	6-phosphofructokinase activity
FNC98_RS08510	COG3279	Response regulator of the LytR AlgR family
FNC98_RS08515	COG2972	Histidine kinase
FNC98_RS08520	COG1607	acyl-coa hydrolase
FNC98_RS08525	COG0537	adenosine 5'-monophosphoramidase activity
FNC98_RS08575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNC98_RS08580	COG0322	excinuclease ABC activity
FNC98_RS08585	COG2197	response regulator
FNC98_RS08595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNC98_RS08605	COG0488	(ABC) transporter
FNC98_RS08615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNC98_RS08615	COG0116	Belongs to the methyltransferase superfamily
FNC98_RS08645	COG1254	Belongs to the acylphosphatase family
FNC98_RS08650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNC98_RS08660	COG1643	Atp-dependent helicase
FNC98_RS08665	COG4109	DRTGG domain
FNC98_RS08680	COG0745	RESPONSE REGULATOR receiver
FNC98_RS08685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNC98_RS08690	COG1074	ATP-dependent DNA helicase activity
FNC98_RS08695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FNC98_RS08710	COG2925	Exonuclease
FNC98_RS08725	COG2084	Dehydrogenase
FNC98_RS08730	COG0386	Belongs to the glutathione peroxidase family
FNC98_RS08735	COG0527	aspartate kinase activity
FNC98_RS08740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNC98_RS08750	COG1136	(ABC) transporter
FNC98_RS08755	COG0577	efflux transmembrane transporter activity
FNC98_RS08775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNC98_RS08825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNC98_RS08845	COG2226	methyltransferase
FNC98_RS08855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNC98_RS08860	COG1388	LysM domain
FNC98_RS08860	COG0741	lytic transglycosylase activity
FNC98_RS08875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNC98_RS08880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNC98_RS08885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNC98_RS08890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNC98_RS08905	COG3001	Fructosamine kinase
FNC98_RS08915	COG0307	riboflavin synthase, alpha
FNC98_RS08940	COG0280	phosphate acetyltransferase
FNC98_RS08940	COG0857	belongs to the CobB CobQ family
FNC98_RS08950	COG0589	response to stress
FNC98_RS08965	COG0028	Belongs to the TPP enzyme family
FNC98_RS09015	COG0842	Transport permease protein
FNC98_RS09020	COG1131	(ABC) transporter
FNC98_RS09030	COG1597	lipid kinase activity
FNC98_RS09035	COG2205	protein histidine kinase activity
FNC98_RS09040	COG0745	RESPONSE REGULATOR receiver
FNC98_RS09065	COG0714	Associated with various cellular activities
FNC98_RS09075	COG0312	modulator of DNA gyrase
FNC98_RS09080	COG0312	modulator of DNA gyrase
FNC98_RS09085	COG0708	Exodeoxyribonuclease III
FNC98_RS09090	COG2226	methyltransferase
FNC98_RS09110	COG1393	Belongs to the ArsC family
FNC98_RS09115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNC98_RS09120	COG1876	peptidase activity
FNC98_RS09130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FNC98_RS09135	COG2716	regulation of RNA biosynthetic process
FNC98_RS09140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNC98_RS09150	COG0425	Belongs to the sulfur carrier protein TusA family
FNC98_RS09155	COG4783	chaperone-mediated protein folding
FNC98_RS09160	COG1393	Belongs to the ArsC family
FNC98_RS09175	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNC98_RS09185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNC98_RS09190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNC98_RS09205	COG0121	glutamine amidotransferase
FNC98_RS09210	COG1960	acyl-CoA dehydrogenase activity
FNC98_RS09245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FNC98_RS09255	COG0045	succinate-CoA ligase (ADP-forming) activity
FNC98_RS09260	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNC98_RS09265	COG0567	Dehydrogenase, E1 component
FNC98_RS09270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNC98_RS09275	COG1053	succinate dehydrogenase
FNC98_RS09280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FNC98_RS09305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNC98_RS09310	COG3485	protocatechuate 3,4-dioxygenase
FNC98_RS09340	COG1794	racemase activity, acting on amino acids and derivatives
FNC98_RS09345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNC98_RS09370	COG1185	polyribonucleotide nucleotidyltransferase activity
FNC98_RS09385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNC98_RS09390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNC98_RS09395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNC98_RS09400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNC98_RS09405	COG0195	Participates in both transcription termination and antitermination
FNC98_RS09410	COG0779	Required for maturation of 30S ribosomal subunits
FNC98_RS09420	COG3459	Glycosyltransferase 36 associated
FNC98_RS09425	COG2211	Major facilitator Superfamily
FNC98_RS09430	COG0330	HflC and HflK could
FNC98_RS09465	COG0640	Transcriptional regulator
FNC98_RS09485	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FNC98_RS09505	COG0189	ligase activity
FNC98_RS09515	COG0189	ligase activity
FNC98_RS09515	COG4067	protein conserved in archaea
FNC98_RS09520	COG3264	Mechanosensitive ion channel
FNC98_RS09520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FNC98_RS09525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNC98_RS09540	COG4974	Belongs to the 'phage' integrase family
FNC98_RS09560	COG2801	Transposase and inactivated derivatives
FNC98_RS09600	COG3311	Transcriptional regulator
FNC98_RS09610	COG0582	viral genome integration into host DNA
FNC98_RS09620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNC98_RS09625	COG0149	triose-phosphate isomerase activity
FNC98_RS09630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNC98_RS09635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNC98_RS09640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNC98_RS09645	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FNC98_RS09650	COG1534	Rna-binding protein
FNC98_RS09665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNC98_RS09670	COG0505	Belongs to the CarA family
FNC98_RS09675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNC98_RS09680	COG0545	Peptidyl-prolyl cis-trans isomerase
FNC98_RS09695	COG0488	(ABC) transporter
FNC98_RS09710	COG0513	Belongs to the DEAD box helicase family
FNC98_RS09715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNC98_RS09765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNC98_RS09780	COG0435	Glutathione S-transferase
FNC98_RS09785	COG2259	Doxx family
FNC98_RS09810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNC98_RS09820	COG3590	peptidase
FNC98_RS09870	COG2176	DNA-directed DNA polymerase activity
FNC98_RS09880	COG0745	RESPONSE REGULATOR receiver
FNC98_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS09935	COG0385	Bile acid
FNC98_RS09945	COG4953	penicillin-binding protein 1C
FNC98_RS09950	COG2373	Large extracellular alpha-helical protein
FNC98_RS09960	COG3064	Membrane
FNC98_RS09975	COG0419	ATPase involved in DNA repair
FNC98_RS09980	COG0420	3'-5' exonuclease activity
FNC98_RS10005	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS10005	COG1506	peptidase
FNC98_RS10015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNC98_RS10025	COG1760	l-serine dehydratase
FNC98_RS10040	COG1388	LysM domain
FNC98_RS10040	COG1470	cell adhesion involved in biofilm formation
FNC98_RS10045	COG1301	dicarboxylic acid transport
FNC98_RS10050	COG0500	methyltransferase
FNC98_RS10055	COG0500	methyltransferase
FNC98_RS10060	COG0616	signal peptide processing
FNC98_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS10075	COG2890	protein-(glutamine-N5) methyltransferase activity
FNC98_RS10080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNC98_RS10085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNC98_RS10090	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FNC98_RS10095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNC98_RS10105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNC98_RS10110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNC98_RS10115	COG0193	aminoacyl-tRNA hydrolase activity
FNC98_RS10145	COG1022	Amp-dependent synthetase and ligase
FNC98_RS10155	COG1278	Cold shock
FNC98_RS10165	COG0564	pseudouridine synthase activity
FNC98_RS10170	COG3098	single-species biofilm formation
FNC98_RS10195	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FNC98_RS10200	COG1194	a g-specific adenine glycosylase
FNC98_RS10205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNC98_RS10215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNC98_RS10260	COG1404	Belongs to the peptidase S8 family
FNC98_RS10275	COG0745	RESPONSE REGULATOR receiver
FNC98_RS10290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNC98_RS10295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNC98_RS10300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNC98_RS10305	COG2204	response regulator
FNC98_RS10310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNC98_RS10325	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNC98_RS10330	COG1757	Na H antiporter
FNC98_RS10340	COG4948	Mandelate Racemase Muconate Lactonizing
FNC98_RS10360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNC98_RS10405	COG1611	Belongs to the LOG family
FNC98_RS10410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNC98_RS10420	COG0473	3-isopropylmalate dehydrogenase activity
FNC98_RS10430	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FNC98_RS10445	COG0583	DNA-binding transcription factor activity
FNC98_RS10450	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FNC98_RS10460	COG2912	Transglutaminase-like superfamily
FNC98_RS10480	COG0825	malonyl-CoA metabolic process
FNC98_RS10485	COG0587	DNA-directed DNA polymerase activity
FNC98_RS10490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNC98_RS10495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNC98_RS10500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNC98_RS10505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNC98_RS10510	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNC98_RS10530	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNC98_RS10535	COG0575	Belongs to the CDS family
FNC98_RS10540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNC98_RS10545	COG0233	cytoplasmic translational termination
FNC98_RS10550	COG0528	UMP kinase activity
FNC98_RS10560	COG0052	Belongs to the universal ribosomal protein uS2 family
FNC98_RS10565	COG0024	Methionine aminopeptidase
FNC98_RS10570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNC98_RS10575	COG2171	N-acyltransferase activity
FNC98_RS10590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FNC98_RS10595	COG2835	tetraacyldisaccharide 4'-kinase activity
FNC98_RS10605	COG1132	(ABC) transporter
FNC98_RS10610	COG0658	competence protein
FNC98_RS10610	COG2333	competence protein COMEC
FNC98_RS10620	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNC98_RS10635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNC98_RS10660	COG1187	pseudouridine synthase activity
FNC98_RS10685	COG4336	lyase activity
FNC98_RS10695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNC98_RS10700	COG1984	allophanate hydrolase subunit 2
FNC98_RS10720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNC98_RS10730	COG0589	response to stress
FNC98_RS10755	COG1024	Enoyl-CoA hydratase
FNC98_RS10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNC98_RS10760	COG0183	Belongs to the thiolase family
FNC98_RS10765	COG0714	Associated with various cellular activities
FNC98_RS10795	COG1595	DNA-templated transcription, initiation
FNC98_RS10805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS10810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FNC98_RS10820	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS10830	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS10880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNC98_RS10885	COG3104	oligopeptide transport
FNC98_RS10890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FNC98_RS10900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNC98_RS10905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNC98_RS10915	COG2853	Lipoprotein
FNC98_RS10940	COG0582	viral genome integration into host DNA
FNC98_RS10980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNC98_RS10990	COG0126	phosphoglycerate kinase activity
FNC98_RS11015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNC98_RS11025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNC98_RS11030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNC98_RS11035	COG0740	serine-type endopeptidase activity
FNC98_RS11040	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNC98_RS11065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNC98_RS11070	COG0215	cysteine-tRNA ligase activity
FNC98_RS11075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNC98_RS11080	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNC98_RS11105	COG1012	belongs to the aldehyde dehydrogenase family
FNC98_RS11120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNC98_RS11125	COG1286	toxin biosynthetic process
FNC98_RS11135	COG0285	dihydrofolate synthase activity
FNC98_RS11140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNC98_RS11145	COG0101	tRNA pseudouridine synthase activity
FNC98_RS11155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNC98_RS11165	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNC98_RS11175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNC98_RS11200	COG3101	peptidyl-lysine hydroxylation
FNC98_RS11225	COG0484	heat shock protein binding
FNC98_RS11230	COG0443	Heat shock 70 kDa protein
FNC98_RS11235	COG3437	response regulator, receiver
FNC98_RS11240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNC98_RS11245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNC98_RS11260	COG3710	Transcriptional regulator
FNC98_RS11275	COG0513	Belongs to the DEAD box helicase family
FNC98_RS11280	COG1115	amino acid carrier protein
FNC98_RS11290	COG0697	spore germination
FNC98_RS11300	COG1228	amidohydrolase
FNC98_RS11310	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FNC98_RS11315	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FNC98_RS11340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNC98_RS11350	COG2971	BadF BadG BcrA BcrD
FNC98_RS11380	COG1609	Transcriptional regulator
FNC98_RS11385	COG1309	transcriptional regulator
FNC98_RS11395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS11430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNC98_RS11440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNC98_RS11445	COG1702	phosphate starvation-inducible protein PhoH
FNC98_RS11450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNC98_RS11455	COG4535	Mg2 and Co2 transporter CorC
FNC98_RS11460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNC98_RS11465	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNC98_RS11470	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FNC98_RS11480	COG0071	Belongs to the small heat shock protein (HSP20) family
FNC98_RS11505	COG0604	alcohol dehydrogenase
FNC98_RS11505	COG3321	synthase
FNC98_RS11520	COG1131	(ABC) transporter
FNC98_RS11525	COG0071	Belongs to the small heat shock protein (HSP20) family
FNC98_RS11530	COG0513	Belongs to the DEAD box helicase family
FNC98_RS11535	COG1278	Cold shock
FNC98_RS11690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNC98_RS11710	COG1088	dTDP-glucose 4,6-dehydratase activity
FNC98_RS11715	COG1091	dTDP-4-dehydrorhamnose reductase activity
FNC98_RS11755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNC98_RS11760	COG1596	polysaccharide export
FNC98_RS11790	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNC98_RS11825	COG1278	Cold shock
FNC98_RS11875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNC98_RS11890	COG0572	uridine kinase
FNC98_RS11925	COG0463	Glycosyl transferase, family 2
FNC98_RS11950	COG0489	protein tyrosine kinase activity
FNC98_RS11950	COG3206	protein involved in exopolysaccharide biosynthesis
FNC98_RS11965	COG1388	LysM domain
FNC98_RS11965	COG4942	peptidase
FNC98_RS11970	COG1238	metal cluster binding
FNC98_RS11975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNC98_RS11980	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FNC98_RS11990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNC98_RS11995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNC98_RS12000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FNC98_RS12020	COG0504	CTP synthase activity
FNC98_RS12040	COG3956	TIGRFAM MazG family protein
FNC98_RS12045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNC98_RS12055	COG4999	Histidine kinase
FNC98_RS12055	COG3850	Histidine kinase
FNC98_RS12055	COG3437	response regulator, receiver
FNC98_RS12055	COG2205	protein histidine kinase activity
FNC98_RS12060	COG0736	holo-[acyl-carrier-protein] synthase activity
FNC98_RS12065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FNC98_RS12070	COG1381	Involved in DNA repair and RecF pathway recombination
FNC98_RS12080	COG0571	ribonuclease III activity
FNC98_RS12090	COG0481	GTPase activity
FNC98_RS12110	COG1595	DNA-templated transcription, initiation
FNC98_RS12115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNC98_RS12120	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FNC98_RS12170	COG0542	response to heat
FNC98_RS12180	COG0564	pseudouridine synthase activity
FNC98_RS12185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNC98_RS12200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNC98_RS12220	COG4968	Prepilin-type N-terminal cleavage methylation domain
FNC98_RS12275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNC98_RS12280	COG1047	Peptidyl-prolyl cis-trans
FNC98_RS12290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNC98_RS12295	COG0196	riboflavin kinase activity
FNC98_RS12300	COG0728	peptidoglycan biosynthetic process
FNC98_RS12305	COG0268	Binds directly to 16S ribosomal RNA
FNC98_RS12310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FNC98_RS12320	COG0730	response to heat
FNC98_RS12330	COG1051	belongs to the nudix hydrolase family
FNC98_RS12335	COG3066	DNA modification
FNC98_RS12340	COG0676	glucose-6-phosphate 1-epimerase activity
FNC98_RS12390	COG4964	Belongs to the GSP D family
FNC98_RS12415	COG2989	Protein conserved in bacteria
FNC98_RS12435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNC98_RS12450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNC98_RS12460	COG0366	Alpha amylase catalytic
FNC98_RS12485	COG0243	molybdopterin cofactor binding
FNC98_RS12515	COG1404	Belongs to the peptidase S8 family
FNC98_RS12540	COG3766	membrane
FNC98_RS12550	COG0754	glutathionylspermidine amidase activity
FNC98_RS12555	COG0531	amino acid
FNC98_RS12570	COG0583	DNA-binding transcription factor activity
FNC98_RS12575	COG0450	alkyl hydroperoxide reductase
FNC98_RS12615	COG0798	PFAM Bile acid sodium symporter
FNC98_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS12635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNC98_RS12650	COG1288	antiporter activity
FNC98_RS12655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNC98_RS12660	COG3046	protein related to deoxyribodipyrimidine photolyase
FNC98_RS12670	COG0415	Belongs to the DNA photolyase family
FNC98_RS12680	COG2239	Acts as a magnesium transporter
FNC98_RS12695	COG0583	DNA-binding transcription factor activity
FNC98_RS12705	COG0189	ligase activity
FNC98_RS12715	COG2271	Major facilitator Superfamily
FNC98_RS12745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNC98_RS12755	COG0405	Gamma-glutamyltransferase
FNC98_RS12760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNC98_RS12760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNC98_RS12765	COG0509	glycine decarboxylation via glycine cleavage system
FNC98_RS12770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNC98_RS12780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNC98_RS12790	COG1233	COG1233 Phytoene dehydrogenase and related
FNC98_RS12795	COG4221	oxidoreductase activity
FNC98_RS12805	COG0415	Belongs to the DNA photolyase family
FNC98_RS12815	COG3806	Anti-sigma factor
FNC98_RS12820	COG1595	DNA-templated transcription, initiation
FNC98_RS12845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS12850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNC98_RS12855	COG3876	Protein conserved in bacteria
FNC98_RS12895	COG0745	RESPONSE REGULATOR receiver
FNC98_RS12900	COG2205	protein histidine kinase activity
FNC98_RS12930	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNC98_RS12935	COG2267	carboxylic ester hydrolase activity
FNC98_RS12960	COG1216	Glycosyl transferase, family 2
FNC98_RS12960	COG0463	Glycosyl transferase, family 2
FNC98_RS12965	COG4628	conserved protein (DUF2132)
FNC98_RS12975	COG3273	potassium ion transport
FNC98_RS12975	COG0471	metal ion transport
FNC98_RS12980	COG1285	pathogenesis
FNC98_RS12985	COG1132	(ABC) transporter
FNC98_RS13000	COG3250	beta-galactosidase activity
FNC98_RS13010	COG0500	methyltransferase
FNC98_RS13025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNC98_RS13075	COG2003	Belongs to the UPF0758 family
FNC98_RS13125	COG0582	viral genome integration into host DNA
FNC98_RS13130	COG0582	viral genome integration into host DNA
FNC98_RS13145	COG0795	lipopolysaccharide-transporting ATPase activity
FNC98_RS13150	COG0795	lipopolysaccharide-transporting ATPase activity
FNC98_RS13155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNC98_RS13165	COG0525	valine-tRNA ligase activity
FNC98_RS13175	COG1473	amidohydrolase
FNC98_RS13180	COG1960	acyl-CoA dehydrogenase activity
FNC98_RS13185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS13215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNC98_RS13220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNC98_RS13225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNC98_RS13245	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FNC98_RS13250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FNC98_RS13255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNC98_RS13260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FNC98_RS13265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNC98_RS13270	COG2967	ApaG domain
FNC98_RS13280	COG2837	iron assimilation
FNC98_RS13285	COG1438	arginine binding
FNC98_RS13290	COG0039	L-malate dehydrogenase activity
FNC98_RS13295	COG0142	geranyltranstransferase activity
FNC98_RS13300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNC98_RS13305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNC98_RS13310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNC98_RS13320	COG0281	malic enzyme
FNC98_RS13340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNC98_RS13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNC98_RS13365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNC98_RS13375	COG0460	homoserine dehydrogenase
FNC98_RS13375	COG0527	aspartate kinase activity
FNC98_RS13385	COG3141	response to X-ray
FNC98_RS13405	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FNC98_RS13415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNC98_RS13430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNC98_RS13435	COG0640	Transcriptional regulator
FNC98_RS13450	COG3150	esterase
FNC98_RS13465	COG0494	nUDIX hydrolase
FNC98_RS13470	COG1538	Outer membrane efflux protein
FNC98_RS13475	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FNC98_RS13475	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNC98_RS13480	COG1560	Kdo2-lipid A biosynthetic process
FNC98_RS13485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNC98_RS13515	COG3025	triphosphatase activity
FNC98_RS13520	COG4991	sh3 domain protein
FNC98_RS13535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNC98_RS13545	COG0473	3-isopropylmalate dehydrogenase activity
FNC98_RS13550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNC98_RS13555	COG0066	3-isopropylmalate dehydratase activity
FNC98_RS13565	COG3409	Peptidoglycan-binding domain 1 protein
FNC98_RS13565	COG3267	Type II secretory pathway component ExeA
FNC98_RS13570	COG0617	tRNA 3'-terminal CCA addition
FNC98_RS13575	COG1968	undecaprenyl-diphosphatase activity
FNC98_RS13580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNC98_RS13585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNC98_RS13590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNC98_RS13600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNC98_RS13605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNC98_RS13610	COG1610	YqeY-like protein
FNC98_RS13615	COG0358	DNA primase activity
FNC98_RS13660	COG2801	Transposase and inactivated derivatives
FNC98_RS13730	COG4232	protein-disulfide reductase activity
FNC98_RS13765	COG0714	Associated with various cellular activities
FNC98_RS13795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNC98_RS13800	COG2326	polyphosphate kinase activity
FNC98_RS13820	COG1196	nuclear chromosome segregation
FNC98_RS13820	COG0739	heme binding
FNC98_RS13820	COG0741	lytic transglycosylase activity
FNC98_RS13855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNC98_RS13875	COG1404	Belongs to the peptidase S8 family
FNC98_RS13880	COG0733	neurotransmitter:sodium symporter activity
FNC98_RS13885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNC98_RS13915	COG2827	Endonuclease containing a URI domain
FNC98_RS13970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS13975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNC98_RS13980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNC98_RS13985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNC98_RS14035	COG4948	Mandelate Racemase Muconate Lactonizing
FNC98_RS14045	COG1376	ErfK ybiS ycfS ynhG family protein
FNC98_RS14045	COG1388	LysM domain
FNC98_RS14055	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FNC98_RS14065	COG0506	proline dehydrogenase activity
FNC98_RS14065	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNC98_RS14065	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNC98_RS14095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNC98_RS14120	COG4771	TonB-dependent receptor
FNC98_RS14130	COG1024	Enoyl-CoA hydratase
FNC98_RS14145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNC98_RS14155	COG0745	RESPONSE REGULATOR receiver
FNC98_RS14165	COG1469	GTP cyclohydrolase I activity
FNC98_RS14175	COG0070	glutamate synthase
FNC98_RS14175	COG0069	glutamate synthase activity
FNC98_RS14175	COG0067	glutamate synthase
FNC98_RS14180	COG0493	'glutamate synthase
FNC98_RS14190	COG1944	ATP diphosphatase activity
FNC98_RS14200	COG1215	transferase activity, transferring glycosyl groups
FNC98_RS14220	COG0346	lactoylglutathione lyase activity
FNC98_RS14230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNC98_RS14235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS14240	COG2017	converts alpha-aldose to the beta-anomer
FNC98_RS14250	COG0456	acetyltransferase
FNC98_RS14270	COG1840	ABC-type Fe3 transport system, periplasmic component
FNC98_RS14325	COG2188	Transcriptional regulator
FNC98_RS14330	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNC98_RS14365	COG0330	HflC and HflK could
FNC98_RS14370	COG0330	HflC and HflK could
FNC98_RS14380	COG2133	pyrroloquinoline quinone binding
FNC98_RS14390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNC98_RS14395	COG0456	acetyltransferase
FNC98_RS14410	COG1295	ribonuclease BN
FNC98_RS14445	COG1217	gtp-binding protein TYPA
FNC98_RS14450	COG0174	glutamine synthetase
FNC98_RS14460	COG3852	Histidine kinase
FNC98_RS14465	COG2204	response regulator
FNC98_RS14475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FNC98_RS14480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNC98_RS14485	COG1509	lysine 2,3-aminomutase activity
FNC98_RS14515	COG0459	protein refolding
FNC98_RS14520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNC98_RS14530	COG1324	tolerance protein
FNC98_RS14535	COG4232	protein-disulfide reductase activity
FNC98_RS14540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNC98_RS14545	COG0511	ligase activity, forming carbon-carbon bonds
FNC98_RS14550	COG0439	Biotin carboxylase
FNC98_RS14565	COG2814	Major facilitator Superfamily
FNC98_RS14585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNC98_RS14595	COG1012	belongs to the aldehyde dehydrogenase family
FNC98_RS14605	COG1765	OsmC-like protein
FNC98_RS14610	COG3954	Phosphoribulokinase
FNC98_RS14615	COG0203	ribosomal protein L17
FNC98_RS14620	COG0202	RNA polymerase activity
FNC98_RS14625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNC98_RS14630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNC98_RS14635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNC98_RS14640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNC98_RS14645	COG0201	protein transport
FNC98_RS14650	COG0200	Binds to the 23S rRNA
FNC98_RS14655	COG1841	ribosomal large subunit assembly
FNC98_RS14660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNC98_RS14670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNC98_RS14675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNC98_RS14685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNC98_RS14690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNC98_RS14700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNC98_RS14705	COG0255	Belongs to the universal ribosomal protein uL29 family
FNC98_RS14710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNC98_RS14715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNC98_RS14720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNC98_RS14725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNC98_RS14730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNC98_RS14735	COG0089	rRNA binding
FNC98_RS14740	COG0088	Forms part of the polypeptide exit tunnel
FNC98_RS14745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNC98_RS14750	COG0051	transcription antitermination factor activity, RNA binding
FNC98_RS14755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNC98_RS14765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNC98_RS14770	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNC98_RS14770	COG1902	pentaerythritol trinitrate reductase activity
FNC98_RS14775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNC98_RS14800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNC98_RS14805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNC98_RS14835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNC98_RS14840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNC98_RS14845	COG0049	tRNA binding
FNC98_RS14850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNC98_RS14855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNC98_RS14860	COG0085	RNA polymerase activity
FNC98_RS14865	COG0222	ribosome binding
FNC98_RS14870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNC98_RS14875	COG0081	regulation of translation
FNC98_RS14880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNC98_RS14895	COG0250	Participates in transcription elongation, termination and antitermination
FNC98_RS14900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNC98_RS14915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNC98_RS14950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNC98_RS14955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNC98_RS14965	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FNC98_RS14970	COG0545	Peptidyl-prolyl cis-trans isomerase
FNC98_RS14975	COG2900	Belongs to the SlyX family
FNC98_RS14980	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FNC98_RS14985	COG0488	(ABC) transporter
FNC98_RS14990	COG0625	glutathione transferase activity
FNC98_RS14995	COG0429	hydrolase of the alpha beta-hydrolase fold
FNC98_RS15000	COG3089	Belongs to the UPF0270 family
FNC98_RS15010	COG1218	3'(2'),5'-bisphosphate nucleotidase
FNC98_RS15015	COG0494	nUDIX hydrolase
FNC98_RS15020	COG1011	Hydrolase
FNC98_RS15030	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNC98_RS15035	COG1309	transcriptional regulator
FNC98_RS15040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNC98_RS15045	COG2003	Belongs to the UPF0758 family
FNC98_RS15050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNC98_RS15055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNC98_RS15065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNC98_RS15070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNC98_RS15080	COG3642	lipopolysaccharide core region biosynthetic process
FNC98_RS15085	COG0859	PFAM glycosyl transferase family 9
FNC98_RS15090	COG1519	Transferase
FNC98_RS15100	COG4946	Tricorn protease homolog
FNC98_RS15100	COG1506	peptidase
FNC98_RS15100	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS15105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FNC98_RS15115	COG0156	8-amino-7-oxononanoate synthase activity
FNC98_RS15120	COG1063	alcohol dehydrogenase
FNC98_RS15125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNC98_RS15145	COG0534	Mate efflux family protein
FNC98_RS15150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNC98_RS15155	COG0514	ATP-dependent DNA helicase (RecQ)
FNC98_RS15160	COG2050	protein possibly involved in aromatic compounds catabolism
FNC98_RS15175	COG2962	Rard protein
FNC98_RS15185	COG0210	DNA helicase
FNC98_RS15205	COG0612	Peptidase, M16
FNC98_RS15215	COG1011	Hydrolase
FNC98_RS15225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNC98_RS15240	COG1965	Belongs to the frataxin family
FNC98_RS15245	COG0181	hydroxymethylbilane synthase activity
FNC98_RS15255	COG2959	enzyme of heme biosynthesis
FNC98_RS15270	COG3119	arylsulfatase activity
FNC98_RS15285	COG2937	Belongs to the GPAT DAPAT family
FNC98_RS15295	COG4628	conserved protein (DUF2132)
FNC98_RS15310	COG0583	DNA-binding transcription factor activity
FNC98_RS15325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNC98_RS15330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNC98_RS15335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNC98_RS15340	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FNC98_RS15345	COG1845	cytochrome c oxidase, subunit III
FNC98_RS15365	COG1612	heme a metabolic process
FNC98_RS15370	COG0109	protoheme IX farnesyltransferase activity
FNC98_RS15385	COG3738	Protein conserved in bacteria
FNC98_RS15390	COG0217	transcriptional regulatory protein
FNC98_RS15410	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS15415	COG0726	polysaccharide deacetylase
FNC98_RS15420	COG0534	Mate efflux family protein
FNC98_RS15425	COG2814	Major facilitator Superfamily
FNC98_RS15435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNC98_RS15440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNC98_RS15450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNC98_RS15470	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNC98_RS15550	COG2301	Belongs to the HpcH HpaI aldolase family
FNC98_RS15555	COG2030	dehydratase
FNC98_RS15565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS15570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNC98_RS15585	COG1476	TRANSCRIPTIONal
FNC98_RS15620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNC98_RS15635	COG4206	TonB-dependent receptor
FNC98_RS15640	COG0471	metal ion transport
FNC98_RS15650	COG4946	Tricorn protease homolog
FNC98_RS15650	COG1506	peptidase
FNC98_RS15650	COG0823	Involved in the tonB-independent uptake of proteins
FNC98_RS15700	COG0583	DNA-binding transcription factor activity
FNC98_RS15705	COG1741	Belongs to the pirin family
FNC98_RS15715	COG0640	Transcriptional regulator
FNC98_RS15735	COG3068	Protein conserved in bacteria
FNC98_RS15740	COG3360	Dodecin
FNC98_RS15745	COG0742	ribosomal rna small subunit methyltransferase
FNC98_RS15750	COG0552	protein localization to endoplasmic reticulum
FNC98_RS15755	COG2884	Cell division ATP-binding protein ftsE
FNC98_RS15760	COG2177	Part of the ABC transporter FtsEX involved in
FNC98_RS15785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNC98_RS15790	COG0129	dihydroxy-acid dehydratase activity
FNC98_RS15815	COG0583	DNA-binding transcription factor activity
FNC98_RS15820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNC98_RS15830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNC98_RS15835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNC98_RS15850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNC98_RS15860	COG4771	TonB-dependent receptor
FNC98_RS15865	COG0457	Tetratricopeptide repeat
FNC98_RS15870	COG0668	transmembrane transport
FNC98_RS15875	COG1946	Acyl-CoA thioesterase
FNC98_RS15885	COG1683	Conserved Protein
FNC98_RS15945	COG1082	Xylose isomerase domain protein TIM barrel
FNC98_RS15970	COG4989	oxidoreductase activity
FNC98_RS15985	COG2911	Protein conserved in bacteria
FNC98_RS15990	COG0729	surface antigen
FNC98_RS16010	COG3118	belongs to the thioredoxin family
FNC98_RS16015	COG0513	Belongs to the DEAD box helicase family
FNC98_RS16020	COG0248	Ppx GppA phosphatase
FNC98_RS16055	COG0805	protein transport
FNC98_RS16060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNC98_RS16085	COG2226	methyltransferase
FNC98_RS16090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNC98_RS16095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNC98_RS16105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNC98_RS16110	COG1758	RNA polymerase activity
FNC98_RS16115	COG0194	GDP metabolic process
FNC98_RS16135	COG1448	Aminotransferase
FNC98_RS16155	COG2193	ferroxidase activity
FNC98_RS16170	COG0668	transmembrane transport
FNC98_RS16200	COG3201	nicotinamide mononucleotide transporter
FNC98_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS16300	COG4372	Transposase
FNC98_RS16310	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNC98_RS16330	COG3177	Filamentation induced by cAMP protein fic
FNC98_RS16350	COG1561	YicC-like family, N-terminal region
FNC98_RS16375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNC98_RS16380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNC98_RS16395	COG0668	transmembrane transport
FNC98_RS16405	COG0596	Alpha beta hydrolase
FNC98_RS16410	COG1040	competence protein
FNC98_RS16420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FNC98_RS16420	COG0316	Belongs to the HesB IscA family
FNC98_RS16455	COG2321	neutral zinc metallopeptidase
FNC98_RS16485	COG1640	4-alpha-glucanotransferase
FNC98_RS16495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNC98_RS16500	COG0058	SHG alpha-glucan phosphorylase activity
FNC98_RS16515	COG0154	amidase activity
FNC98_RS16520	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNC98_RS16535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNC98_RS16540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNC98_RS16565	COG2268	Band 7 protein
FNC98_RS16575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNC98_RS16595	COG1505	serine-type exopeptidase activity
FNC98_RS16635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNC98_RS16645	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNC98_RS16650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNC98_RS16655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNC98_RS16660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNC98_RS16665	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNC98_RS16685	COG1475	DNA binding
FNC98_RS16690	COG1192	Involved in chromosome partitioning
FNC98_RS16695	COG0357	Ribosomal RNA small subunit methyltransferase G
FNC98_RS16700	COG0445	tRNA wobble uridine modification
FNC98_RS16710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNC98_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
FNC98_RS16720	COG4989	oxidoreductase activity
FNC98_RS16735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNC98_RS16740	COG0594	ribonuclease P activity
FNC98_RS16745	COG0230	Belongs to the bacterial ribosomal protein bL34 family