locus-tag	class	description
DYI95_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DYI95_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DYI95_RS00030	COG0187	DNA topoisomerase II activity
DYI95_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DYI95_RS00040	COG0709	Synthesizes selenophosphate from selenide and ATP
DYI95_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYI95_RS00070	COG0697	spore germination
DYI95_RS00085	COG0531	amino acid
DYI95_RS00090	COG4708	membrane
DYI95_RS00120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DYI95_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DYI95_RS00130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DYI95_RS00145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYI95_RS00180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DYI95_RS00185	COG3870	Protein conserved in bacteria
DYI95_RS00205	COG2002	toxin-antitoxin pair type II binding
DYI95_RS00210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI95_RS00210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI95_RS00215	COG0084	hydrolase, TatD family'
DYI95_RS00220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYI95_RS00225	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DYI95_RS00235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DYI95_RS00240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DYI95_RS00245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYI95_RS00250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYI95_RS00255	COG2088	sporulation resulting in formation of a cellular spore
DYI95_RS00270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DYI95_RS00275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYI95_RS00280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYI95_RS00285	COG0193	aminoacyl-tRNA hydrolase activity
DYI95_RS00290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DYI95_RS00295	COG2002	toxin-antitoxin pair type II binding
DYI95_RS00300	COG3956	TIGRFAM MazG family protein
DYI95_RS00340	COG1283	sodium-dependent phosphate transmembrane transporter activity
DYI95_RS00345	COG0492	ferredoxin-NADP+ reductase activity
DYI95_RS00360	COG0822	iron-sulfur transferase activity
DYI95_RS00365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYI95_RS00370	COG0719	Fe-S assembly protein
DYI95_RS00375	COG0396	ATPase activity
DYI95_RS00380	COG1363	Peptidase, m42
DYI95_RS00385	COG2009	succinate dehydrogenase
DYI95_RS00400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYI95_RS00410	COG2096	Adenosyltransferase
DYI95_RS00430	COG1260	myo-inositol-1-phosphate synthase
DYI95_RS00435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DYI95_RS00435	COG1213	nucleotidyl transferase
DYI95_RS00440	COG2135	peptidase activity
DYI95_RS00470	COG0037	tRNA processing
DYI95_RS00475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYI95_RS00480	COG0617	tRNA 3'-terminal CCA addition
DYI95_RS00490	COG2986	histidine ammonia-lyase
DYI95_RS00495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYI95_RS00505	COG3191	aminopeptidase activity
DYI95_RS00510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DYI95_RS00525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYI95_RS00530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DYI95_RS00560	COG0572	uridine kinase
DYI95_RS00570	COG1404	Belongs to the peptidase S8 family
DYI95_RS00575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYI95_RS00580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DYI95_RS00590	COG0254	rRNA binding
DYI95_RS00600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DYI95_RS00605	COG2890	protein-(glutamine-N5) methyltransferase activity
DYI95_RS00610	COG0009	L-threonylcarbamoyladenylate synthase
DYI95_RS00615	COG0698	ribose 5-phosphate isomerase
DYI95_RS00620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYI95_RS00625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DYI95_RS00640	COG0356	it plays a direct role in the translocation of protons across the membrane
DYI95_RS00645	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYI95_RS00650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DYI95_RS00655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYI95_RS00660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DYI95_RS00665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DYI95_RS00670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DYI95_RS00675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DYI95_RS00680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYI95_RS00685	COG2385	sporulation resulting in formation of a cellular spore
DYI95_RS00695	COG1609	Transcriptional regulator
DYI95_RS00700	COG1077	Cell shape determining protein MreB Mrl
DYI95_RS00710	COG4786	Flagellar basal body rod
DYI95_RS00720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYI95_RS00725	COG2183	response to ionizing radiation
DYI95_RS00730	COG0561	phosphatase activity
DYI95_RS00745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DYI95_RS00750	COG1516	flagellar protein fliS
DYI95_RS00760	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYI95_RS00775	COG1040	competence protein
DYI95_RS00795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DYI95_RS00800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYI95_RS00825	COG0653	protein targeting
DYI95_RS00835	COG2884	Cell division ATP-binding protein ftsE
DYI95_RS00840	COG2177	Part of the ABC transporter FtsEX involved in
DYI95_RS00845	COG0739	heme binding
DYI95_RS00850	COG0793	Belongs to the peptidase S41A family
DYI95_RS00860	COG0556	nucleotide-excision repair
DYI95_RS00865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYI95_RS00870	COG0628	permease
DYI95_RS00880	COG0322	excinuclease ABC activity
DYI95_RS00890	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DYI95_RS00895	COG1950	PFAM Membrane protein of
DYI95_RS00900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DYI95_RS00905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYI95_RS00910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DYI95_RS00915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYI95_RS00920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYI95_RS00925	COG0287	Prephenate dehydrogenase
DYI95_RS00930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYI95_RS00950	COG2239	Acts as a magnesium transporter
DYI95_RS00975	COG1660	Displays ATPase and GTPase activities
DYI95_RS00980	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DYI95_RS00985	COG1481	regulation of sporulation
DYI95_RS00995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DYI95_RS01000	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DYI95_RS01010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYI95_RS01015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYI95_RS01025	COG1131	(ABC) transporter
DYI95_RS01030	COG2188	Transcriptional regulator
DYI95_RS01035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYI95_RS01045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYI95_RS01055	COG2309	aminopeptidase activity
DYI95_RS01060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DYI95_RS01070	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYI95_RS01080	COG0640	Transcriptional regulator
DYI95_RS01085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYI95_RS01090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYI95_RS01090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYI95_RS01095	COG0425	Belongs to the sulfur carrier protein TusA family
DYI95_RS01095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DYI95_RS01100	COG2210	Belongs to the sulfur carrier protein TusA family
DYI95_RS01105	COG0730	response to heat
DYI95_RS01120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DYI95_RS01125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYI95_RS01130	COG0736	holo-[acyl-carrier-protein] synthase activity
DYI95_RS01135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYI95_RS01135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYI95_RS01140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYI95_RS01150	COG2337	Toxic component of a toxin-antitoxin (TA) module
DYI95_RS01160	COG1573	uracil-dna glycosylase
DYI95_RS01165	COG0802	atpase or kinase
DYI95_RS01175	COG0456	acetyltransferase
DYI95_RS01180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DYI95_RS01185	COG0110	maltose O-acetyltransferase activity
DYI95_RS01190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYI95_RS01195	COG0517	IMP dehydrogenase activity
DYI95_RS01195	COG0516	GMP reductase activity
DYI95_RS01200	COG0285	dihydrofolate synthase activity
DYI95_RS01205	COG0183	Belongs to the thiolase family
DYI95_RS01210	COG0303	'Molybdopterin
DYI95_RS01215	COG0315	cyclic pyranopterin monophosphate synthase activity
DYI95_RS01220	COG0521	Mo-molybdopterin cofactor biosynthetic process
DYI95_RS01220	COG0315	cyclic pyranopterin monophosphate synthase activity
DYI95_RS01225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DYI95_RS01230	COG0459	protein refolding
DYI95_RS01235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYI95_RS01235	COG0519	Catalyzes the synthesis of GMP from XMP
DYI95_RS01240	COG5002	protein histidine kinase activity
DYI95_RS01250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYI95_RS01255	COG0444	Belongs to the ABC transporter superfamily
DYI95_RS01260	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS01265	COG4166	transmembrane transport
DYI95_RS01270	COG0601	transmembrane transport
DYI95_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYI95_RS01280	COG0444	Belongs to the ABC transporter superfamily
DYI95_RS01285	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS01300	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS01310	COG0006	proline dipeptidase activity
DYI95_RS01315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYI95_RS01320	COG0154	amidase activity
DYI95_RS01325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYI95_RS01335	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DYI95_RS01360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI95_RS01365	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI95_RS01370	COG0649	NAD binding
DYI95_RS01375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DYI95_RS01380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI95_RS01395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYI95_RS01405	COG1007	ATP synthesis coupled electron transport
DYI95_RS01415	COG0475	glutathione-regulated potassium exporter activity
DYI95_RS01425	COG2010	Cytochrome c
DYI95_RS01440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DYI95_RS01445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYI95_RS01460	COG0697	spore germination
DYI95_RS01485	COG1305	Transglutaminase-like
DYI95_RS01495	COG0714	Associated with various cellular activities
DYI95_RS01505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYI95_RS01520	COG2267	carboxylic ester hydrolase activity
DYI95_RS01525	COG4086	secreted protein
DYI95_RS01530	COG0586	Pfam SNARE associated Golgi protein
DYI95_RS01540	COG2385	sporulation resulting in formation of a cellular spore
DYI95_RS01560	COG0436	Aminotransferase
DYI95_RS01565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DYI95_RS01585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DYI95_RS01595	COG1765	OsmC-like protein
DYI95_RS01600	COG0730	response to heat
DYI95_RS01610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DYI95_RS01620	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DYI95_RS01625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYI95_RS01630	COG2718	Belongs to the UPF0229 family
DYI95_RS01635	COG2719	SpoVR family
DYI95_RS01640	COG2766	serine protein kinase
DYI95_RS01650	COG0205	6-phosphofructokinase activity
DYI95_RS01660	COG2151	metal-sulfur cluster biosynthetic enzyme
DYI95_RS01660	COG0489	protein tyrosine kinase activity
DYI95_RS01665	COG1073	alpha beta
DYI95_RS01685	COG2514	catechol 2,3-dioxygenase activity
DYI95_RS01730	COG0183	Belongs to the thiolase family
DYI95_RS01735	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS01740	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS01755	COG1063	alcohol dehydrogenase
DYI95_RS01760	COG1063	alcohol dehydrogenase
DYI95_RS01765	COG0662	Cupin 2, conserved barrel domain protein
DYI95_RS01780	COG1612	heme a metabolic process
DYI95_RS01785	COG0109	protoheme IX farnesyltransferase activity
DYI95_RS01790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DYI95_RS01795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYI95_RS01800	COG1845	cytochrome c oxidase, subunit III
DYI95_RS01805	COG1845	cytochrome c oxidase, subunit III
DYI95_RS01820	COG2340	Cysteine-rich secretory protein family
DYI95_RS01830	COG0739	heme binding
DYI95_RS01850	COG1404	Belongs to the peptidase S8 family
DYI95_RS01860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DYI95_RS01870	COG3773	Cell wall hydrolase
DYI95_RS01870	COG3409	Peptidoglycan-binding domain 1 protein
DYI95_RS01875	COG3409	Peptidoglycan-binding domain 1 protein
DYI95_RS01875	COG3773	Cell wall hydrolase
DYI95_RS01885	COG0237	dephospho-CoA kinase activity
DYI95_RS01905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYI95_RS01910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYI95_RS01925	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYI95_RS01940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI95_RS01945	COG0202	RNA polymerase activity
DYI95_RS01950	COG2222	sugar isomerase
DYI95_RS01985	COG0346	lactoylglutathione lyase activity
DYI95_RS01995	COG0789	Transcriptional regulator
DYI95_RS02000	COG0174	glutamine synthetase
DYI95_RS02025	COG1132	(ABC) transporter
DYI95_RS02050	COG1494	fructose-1,6-bisphosphatase
DYI95_RS02060	COG2197	response regulator
DYI95_RS02080	COG0693	protein deglycase activity
DYI95_RS02085	COG0725	ABC transporter, periplasmic molybdate-binding protein
DYI95_RS02090	COG4149	molybdate abc transporter
DYI95_RS02100	COG0726	polysaccharide deacetylase
DYI95_RS02105	COG1131	(ABC) transporter
DYI95_RS02125	COG1309	transcriptional regulator
DYI95_RS02135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DYI95_RS02140	COG2181	nitrate reductase activity
DYI95_RS02140	COG0247	lactate metabolic process
DYI95_RS02145	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS02150	COG1607	acyl-coa hydrolase
DYI95_RS02160	COG4948	Mandelate Racemase Muconate Lactonizing
DYI95_RS02175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYI95_RS02185	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DYI95_RS02195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYI95_RS02205	COG0154	amidase activity
DYI95_RS02215	COG0463	Glycosyl transferase, family 2
DYI95_RS02235	COG1178	ABC-type Fe3 transport system permease component
DYI95_RS02255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DYI95_RS02260	COG3663	DNA glycosylase
DYI95_RS02270	COG0477	Major facilitator Superfamily
DYI95_RS02285	COG1940	carbohydrate kinase activity
DYI95_RS02305	COG1121	(ABC) transporter
DYI95_RS02315	COG1131	(ABC) transporter
DYI95_RS02330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DYI95_RS02355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYI95_RS02365	COG1024	Enoyl-CoA hydratase
DYI95_RS02375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYI95_RS02385	COG0011	TIGRFAM Protein of
DYI95_RS02390	COG0477	Major facilitator Superfamily
DYI95_RS02395	COG1388	LysM domain
DYI95_RS02395	COG3942	CHAP domain
DYI95_RS02400	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DYI95_RS02405	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DYI95_RS02410	COG1268	BioY protein
DYI95_RS02415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DYI95_RS02420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DYI95_RS02425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYI95_RS02430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYI95_RS02435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYI95_RS02450	COG0165	Argininosuccinate lyase
DYI95_RS02465	COG1573	uracil-dna glycosylase
DYI95_RS02510	COG4176	ABC-type proline glycine betaine transport system permease component
DYI95_RS02515	COG4175	Glycine betaine
DYI95_RS02530	COG1404	Belongs to the peptidase S8 family
DYI95_RS02560	COG0735	belongs to the Fur family
DYI95_RS02565	COG1121	(ABC) transporter
DYI95_RS02570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYI95_RS02575	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYI95_RS02580	COG2223	nitrite transmembrane transporter activity
DYI95_RS02590	COG1999	signal sequence binding
DYI95_RS02615	COG4946	Tricorn protease homolog
DYI95_RS02615	COG0823	Involved in the tonB-independent uptake of proteins
DYI95_RS02615	COG1506	peptidase
DYI95_RS02625	COG0741	lytic transglycosylase activity
DYI95_RS02635	COG2011	ABC-type metal ion transport system permease component
DYI95_RS02640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYI95_RS02645	COG0367	asparagine synthase
DYI95_RS02650	COG0683	leucine binding
DYI95_RS02655	COG0559	Belongs to the binding-protein-dependent transport system permease family
DYI95_RS02680	COG0697	spore germination
DYI95_RS02690	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI95_RS02695	COG3876	Protein conserved in bacteria
DYI95_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYI95_RS02700	COG1263	PTS System
DYI95_RS02705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DYI95_RS02710	COG2188	Transcriptional regulator
DYI95_RS02715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DYI95_RS02725	COG0561	phosphatase activity
DYI95_RS02730	COG0506	proline dehydrogenase activity
DYI95_RS02735	COG0140	phosphoribosyl-ATP diphosphatase activity
DYI95_RS02735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DYI95_RS02740	COG0107	imidazoleglycerol-phosphate synthase activity
DYI95_RS02745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DYI95_RS02750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DYI95_RS02755	COG0131	Imidazoleglycerol-phosphate dehydratase
DYI95_RS02760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYI95_RS02765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYI95_RS02775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYI95_RS02780	COG0697	spore germination
DYI95_RS02795	COG4496	protein, YerC YecD
DYI95_RS02820	COG1388	LysM domain
DYI95_RS02845	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DYI95_RS02870	COG1063	alcohol dehydrogenase
DYI95_RS02875	COG0235	Class ii aldolase
DYI95_RS02895	COG0668	transmembrane transport
DYI95_RS02910	COG0174	glutamine synthetase
DYI95_RS02920	COG0004	ammonium transporteR
DYI95_RS02925	COG0367	asparagine synthase
DYI95_RS02935	COG1733	regulation of RNA biosynthetic process
DYI95_RS02940	COG2272	Belongs to the type-B carboxylesterase lipase family
DYI95_RS02945	COG0070	glutamate synthase
DYI95_RS02945	COG0069	glutamate synthase activity
DYI95_RS02945	COG0067	glutamate synthase
DYI95_RS02970	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS02995	COG2911	Protein conserved in bacteria
DYI95_RS02995	COG3266	domain, Protein
DYI95_RS02995	COG1361	Conserved repeat domain
DYI95_RS03060	COG2247	cell wall binding repeat
DYI95_RS03060	COG2385	sporulation resulting in formation of a cellular spore
DYI95_RS03065	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS03065	COG0297	glycogen (starch) synthase activity
DYI95_RS03125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DYI95_RS03130	COG1228	amidohydrolase
DYI95_RS03140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYI95_RS03145	COG2318	DinB family
DYI95_RS03150	COG0726	polysaccharide deacetylase
DYI95_RS03180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DYI95_RS03190	COG1459	type II secretion system
DYI95_RS03235	COG0662	Cupin 2, conserved barrel domain protein
DYI95_RS03235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DYI95_RS03240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DYI95_RS03250	COG1619	proteins homologs of microcin C7 resistance protein MccF
DYI95_RS03255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYI95_RS03285	COG0596	Alpha beta hydrolase
DYI95_RS03300	COG0601	transmembrane transport
DYI95_RS03305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYI95_RS03315	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS03320	COG0728	peptidoglycan biosynthetic process
DYI95_RS03355	COG1366	Belongs to the anti-sigma-factor antagonist family
DYI95_RS03380	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS03385	COG3842	ATPase activity
DYI95_RS03390	COG0390	transport system, permease component
DYI95_RS03425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DYI95_RS03435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYI95_RS03440	COG1083	cytidylyl-transferase
DYI95_RS03445	COG2089	acid synthase
DYI95_RS03450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DYI95_RS03455	COG1086	Polysaccharide biosynthesis protein
DYI95_RS03460	COG1442	glycosyl transferase family 8
DYI95_RS03460	COG1216	Glycosyl transferase, family 2
DYI95_RS03470	COG1215	transferase activity, transferring glycosyl groups
DYI95_RS03485	COG0489	protein tyrosine kinase activity
DYI95_RS03495	COG1737	Transcriptional regulator
DYI95_RS03515	COG3716	PTS system mannose fructose sorbose family IID component
DYI95_RS03520	COG4821	SIS domain
DYI95_RS03525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYI95_RS03525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYI95_RS03530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYI95_RS03535	COG4821	SIS domain
DYI95_RS03565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DYI95_RS03570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI95_RS03600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DYI95_RS03610	COG1960	acyl-CoA dehydrogenase activity
DYI95_RS03625	COG1271	oxidase subunit
DYI95_RS03635	COG1316	TRANSCRIPTIONal
DYI95_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS03660	COG1115	amino acid carrier protein
DYI95_RS03675	COG0747	negative chemotaxis
DYI95_RS03680	COG0601	transmembrane transport
DYI95_RS03690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DYI95_RS03700	COG3949	Membrane
DYI95_RS03705	COG1473	amidohydrolase
DYI95_RS03715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI95_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYI95_RS03740	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYI95_RS03750	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DYI95_RS03760	COG4176	ABC-type proline glycine betaine transport system permease component
DYI95_RS03780	COG3311	Transcriptional regulator
DYI95_RS03790	COG2133	pyrroloquinoline quinone binding
DYI95_RS03810	COG5002	protein histidine kinase activity
DYI95_RS03810	COG3850	Histidine kinase
DYI95_RS03815	COG0492	ferredoxin-NADP+ reductase activity
DYI95_RS03820	COG0069	glutamate synthase activity
DYI95_RS03860	COG0483	inositol monophosphate 1-phosphatase activity
DYI95_RS03875	COG1253	flavin adenine dinucleotide binding
DYI95_RS03880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DYI95_RS03895	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DYI95_RS03900	COG1074	ATP-dependent DNA helicase activity
DYI95_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS03915	COG0492	ferredoxin-NADP+ reductase activity
DYI95_RS03930	COG2252	PERMEase
DYI95_RS03960	COG2197	response regulator
DYI95_RS03975	COG0587	DNA-directed DNA polymerase activity
DYI95_RS03985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DYI95_RS04010	COG1254	Belongs to the acylphosphatase family
DYI95_RS04015	COG0730	response to heat
DYI95_RS04025	COG2707	UPF0756 membrane protein
DYI95_RS04035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DYI95_RS04065	COG1164	Oligoendopeptidase f
DYI95_RS04085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYI95_RS04100	COG4399	Belongs to the UPF0754 family
DYI95_RS04105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DYI95_RS04110	COG0747	negative chemotaxis
DYI95_RS04125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DYI95_RS04130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DYI95_RS04135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DYI95_RS04140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYI95_RS04145	COG0569	domain protein
DYI95_RS04150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYI95_RS04160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DYI95_RS04165	COG0072	phenylalanine-tRNA ligase activity
DYI95_RS04165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI95_RS04170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DYI95_RS04175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DYI95_RS04175	COG1796	DNA polymerase
DYI95_RS04180	COG2808	Putative FMN-binding domain
DYI95_RS04185	COG1193	negative regulation of DNA recombination
DYI95_RS04195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DYI95_RS04205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYI95_RS04210	COG0217	transcriptional regulatory protein
DYI95_RS04220	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DYI95_RS04225	COG0632	four-way junction helicase activity
DYI95_RS04230	COG2255	four-way junction helicase activity
DYI95_RS04240	COG1191	sigma factor activity
DYI95_RS04250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYI95_RS04255	COG0343	queuine tRNA-ribosyltransferase activity
DYI95_RS04260	COG1862	Preprotein translocase
DYI95_RS04270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI95_RS04280	COG4770	biotin carboxylase activity
DYI95_RS04285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DYI95_RS04295	COG2001	Belongs to the MraZ family
DYI95_RS04300	COG0275	rRNA processing
DYI95_RS04310	COG0768	penicillin binding
DYI95_RS04315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DYI95_RS04320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYI95_RS04325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYI95_RS04330	COG0772	Belongs to the SEDS family
DYI95_RS04335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYI95_RS04340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DYI95_RS04350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DYI95_RS04360	COG1191	sigma factor activity
DYI95_RS04370	COG1191	sigma factor activity
DYI95_RS04380	COG1873	PFAM PRC-barrel domain
DYI95_RS04390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYI95_RS04395	COG1799	cell septum assembly
DYI95_RS04400	COG0762	integral membrane protein
DYI95_RS04405	COG3599	regulation of cell shape
DYI95_RS04415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYI95_RS04425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DYI95_RS04430	COG1980	fructose-bisphosphate aldolase activity
DYI95_RS04440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYI95_RS04445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DYI95_RS04450	COG0564	pseudouridine synthase activity
DYI95_RS04455	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DYI95_RS04460	COG1929	Belongs to the glycerate kinase type-1 family
DYI95_RS04465	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DYI95_RS04470	COG1024	Enoyl-CoA hydratase
DYI95_RS04470	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYI95_RS04475	COG0183	Belongs to the thiolase family
DYI95_RS04480	COG1960	acyl-CoA dehydrogenase activity
DYI95_RS04485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYI95_RS04490	COG2070	2-Nitropropane dioxygenase
DYI95_RS04530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DYI95_RS04535	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DYI95_RS04540	COG0436	Aminotransferase
DYI95_RS04550	COG1561	YicC-like family, N-terminal region
DYI95_RS04555	COG2052	Domain of unknown function (DUF370)
DYI95_RS04560	COG0194	GDP metabolic process
DYI95_RS04565	COG1758	RNA polymerase activity
DYI95_RS04580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYI95_RS04585	COG2738	Putative neutral zinc metallopeptidase
DYI95_RS04590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYI95_RS04590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYI95_RS04595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DYI95_RS04600	COG0631	protein serine/threonine phosphatase activity
DYI95_RS04605	COG0515	serine threonine protein kinase
DYI95_RS04605	COG2815	serine threonine protein kinase
DYI95_RS04610	COG1162	GTPase activity
DYI95_RS04615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYI95_RS04620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYI95_RS04625	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DYI95_RS04635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DYI95_RS04645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DYI95_RS04650	COG2814	Major facilitator Superfamily
DYI95_RS04660	COG0742	ribosomal rna small subunit methyltransferase
DYI95_RS04665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DYI95_RS04675	COG3314	Sporulation integral membrane protein YlbJ
DYI95_RS04690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DYI95_RS04700	COG0416	fatty acid biosynthetic process
DYI95_RS04705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYI95_RS04710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYI95_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS04720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYI95_RS04725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYI95_RS04730	COG0571	ribonuclease III activity
DYI95_RS04735	COG2359	stage V sporulation protein S
DYI95_RS04740	COG1196	nuclear chromosome segregation
DYI95_RS04745	COG0552	protein localization to endoplasmic reticulum
DYI95_RS04750	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DYI95_RS04755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYI95_RS04760	COG0228	four-way junction DNA binding
DYI95_RS04765	COG1837	Belongs to the UPF0109 family
DYI95_RS04770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYI95_RS04775	COG0336	Belongs to the RNA methyltransferase TrmD family
DYI95_RS04780	COG0335	large ribosomal subunit rRNA binding
DYI95_RS04785	COG0681	Belongs to the peptidase S26 family
DYI95_RS04790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DYI95_RS04795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYI95_RS04800	COG0792	nuclease activity
DYI95_RS04805	COG0606	chelatase, subunit chli
DYI95_RS04810	COG4166	transmembrane transport
DYI95_RS04815	COG0758	DNA mediated transformation
DYI95_RS04815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYI95_RS04820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI95_RS04825	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DYI95_RS04835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DYI95_RS04840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DYI95_RS04845	COG1815	bacterial-type flagellum-dependent cell motility
DYI95_RS04865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYI95_RS04875	COG1157	protein secretion by the type III secretion system
DYI95_RS04895	COG1749	Flagellar hook protein flgE
DYI95_RS04900	COG1582	Flagellar protein (FlbD)
DYI95_RS04910	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYI95_RS04915	COG1776	CheC inhibitor of MCP methylation
DYI95_RS04915	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYI95_RS04930	COG1338	Plays a role in the flagellum-specific transport system
DYI95_RS04935	COG1987	bacterial-type flagellum assembly
DYI95_RS04940	COG1684	flagellar biosynthetic protein fliR
DYI95_RS04945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYI95_RS04950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYI95_RS04960	COG0455	bacterial-type flagellum organization
DYI95_RS04970	COG1191	sigma factor activity
DYI95_RS04985	COG0052	Belongs to the universal ribosomal protein uS2 family
DYI95_RS04990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYI95_RS04995	COG0528	UMP kinase activity
DYI95_RS05000	COG0233	cytoplasmic translational termination
DYI95_RS05015	COG0575	Belongs to the CDS family
DYI95_RS05020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYI95_RS05025	COG0750	zinc metalloprotease
DYI95_RS05030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYI95_RS05035	COG0442	prolyl-tRNA aminoacylation
DYI95_RS05045	COG0779	Required for maturation of 30S ribosomal subunits
DYI95_RS05050	COG0195	Participates in both transcription termination and antitermination
DYI95_RS05055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DYI95_RS05065	COG3170	Tfp pilus assembly protein FimV
DYI95_RS05065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYI95_RS05075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYI95_RS05080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DYI95_RS05085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYI95_RS05090	COG0196	riboflavin kinase activity
DYI95_RS05100	COG1185	polyribonucleotide nucleotidyltransferase activity
DYI95_RS05105	COG0612	Peptidase, M16
DYI95_RS05125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DYI95_RS05135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYI95_RS05140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DYI95_RS05145	COG0527	aspartate kinase activity
DYI95_RS05150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYI95_RS05155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DYI95_RS05160	COG0740	serine-type endopeptidase activity
DYI95_RS05170	COG1968	undecaprenyl-diphosphatase activity
DYI95_RS05175	COG1674	ftsk spoiiie
DYI95_RS05180	COG3858	chitin binding
DYI95_RS05195	COG1809	phosphosulfolactate synthase activity
DYI95_RS05210	COG1960	acyl-CoA dehydrogenase activity
DYI95_RS05215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYI95_RS05220	COG1686	Belongs to the peptidase S11 family
DYI95_RS05225	COG0017	Asparaginyl-tRNA synthetase
DYI95_RS05235	COG1686	Belongs to the peptidase S11 family
DYI95_RS05240	COG0726	polysaccharide deacetylase
DYI95_RS05250	COG1111	helicase
DYI95_RS05250	COG1205	dead DEAH box helicase
DYI95_RS05260	COG1739	Uncharacterized protein family UPF0029
DYI95_RS05270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYI95_RS05275	COG1546	Belongs to the CinA family
DYI95_RS05275	COG1058	Belongs to the CinA family
DYI95_RS05290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYI95_RS05300	COG1418	mRNA catabolic process
DYI95_RS05305	COG1692	metallophosphoesterase
DYI95_RS05315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DYI95_RS05320	COG0613	PHP domain protein
DYI95_RS05335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYI95_RS05350	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYI95_RS05355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYI95_RS05365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYI95_RS05370	COG0464	growth
DYI95_RS05375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYI95_RS05385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DYI95_RS05405	COG2271	Major facilitator Superfamily
DYI95_RS05430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYI95_RS05445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYI95_RS05450	COG0402	S-adenosylhomocysteine deaminase activity
DYI95_RS05455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DYI95_RS05460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DYI95_RS05465	COG0105	UTP biosynthetic process
DYI95_RS05470	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DYI95_RS05480	COG0297	glycogen (starch) synthase activity
DYI95_RS05505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DYI95_RS05515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DYI95_RS05520	COG1160	GTP binding
DYI95_RS05540	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS05540	COG0204	Acyl-transferase
DYI95_RS05545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DYI95_RS05570	COG0644	oxidoreductase
DYI95_RS05575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DYI95_RS05590	COG1187	pseudouridine synthase activity
DYI95_RS05600	COG0700	Nucleoside recognition
DYI95_RS05605	COG2715	membrane protein required for spore maturation
DYI95_RS05610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DYI95_RS05625	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DYI95_RS05630	COG3874	Sporulation protein YtfJ
DYI95_RS05640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DYI95_RS05645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DYI95_RS05650	COG1994	Peptidase M50
DYI95_RS05660	COG0697	spore germination
DYI95_RS05670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYI95_RS05695	COG1366	Belongs to the anti-sigma-factor antagonist family
DYI95_RS05700	COG1686	Belongs to the peptidase S11 family
DYI95_RS05705	COG1921	L-seryl-tRNASec selenium transferase activity
DYI95_RS05710	COG4974	Belongs to the 'phage' integrase family
DYI95_RS05725	COG0494	nUDIX hydrolase
DYI95_RS05755	COG0463	Glycosyl transferase, family 2
DYI95_RS05770	COG0745	RESPONSE REGULATOR receiver
DYI95_RS05780	COG0497	DNA recombination
DYI95_RS05785	COG1438	arginine binding
DYI95_RS05790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYI95_RS05795	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYI95_RS05800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYI95_RS05805	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DYI95_RS05810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYI95_RS05830	COG1570	exodeoxyribonuclease VII activity
DYI95_RS05835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYI95_RS05840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYI95_RS05855	COG1302	Protein conserved in bacteria
DYI95_RS05895	COG3854	ATPases associated with a variety of cellular activities
DYI95_RS05905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYI95_RS05910	COG0006	proline dipeptidase activity
DYI95_RS05915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYI95_RS05920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYI95_RS05925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYI95_RS05930	COG0509	glycine decarboxylation via glycine cleavage system
DYI95_RS05935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DYI95_RS05950	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS06020	COG2201	protein-glutamate methylesterase activity
DYI95_RS06045	COG2197	response regulator
DYI95_RS06055	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DYI95_RS06065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DYI95_RS06070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DYI95_RS06085	COG4472	Bacterial protein of unknown function (DUF965)
DYI95_RS06090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DYI95_RS06100	COG0628	permease
DYI95_RS06115	COG0482	sulfurtransferase activity
DYI95_RS06120	COG1104	cysteine desulfurase activity
DYI95_RS06125	COG1959	2 iron, 2 sulfur cluster binding
DYI95_RS06135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYI95_RS06140	COG1435	thymidine kinase activity
DYI95_RS06155	COG3118	belongs to the thioredoxin family
DYI95_RS06165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DYI95_RS06170	COG0124	histidyl-tRNA synthetase
DYI95_RS06175	COG1490	D-aminoacyl-tRNA deacylase activity
DYI95_RS06180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYI95_RS06185	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DYI95_RS06185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYI95_RS06190	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DYI95_RS06195	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DYI95_RS06195	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DYI95_RS06200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYI95_RS06205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYI95_RS06230	COG1051	belongs to the nudix hydrolase family
DYI95_RS06245	COG1960	acyl-CoA dehydrogenase activity
DYI95_RS06255	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI95_RS06255	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI95_RS06260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI95_RS06260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI95_RS06265	COG0113	porphobilinogen synthase activity
DYI95_RS06270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DYI95_RS06270	COG1648	precorrin-2 dehydrogenase activity
DYI95_RS06275	COG0181	hydroxymethylbilane synthase activity
DYI95_RS06285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DYI95_RS06290	COG2226	methyltransferase
DYI95_RS06295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYI95_RS06300	COG0045	succinate-CoA ligase (ADP-forming) activity
DYI95_RS06305	COG0281	malic enzyme
DYI95_RS06310	COG0039	L-malate dehydrogenase activity
DYI95_RS06320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DYI95_RS06325	COG1131	(ABC) transporter
DYI95_RS06335	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
DYI95_RS06345	COG2002	toxin-antitoxin pair type II binding
DYI95_RS06350	COG4472	Bacterial protein of unknown function (DUF965)
DYI95_RS06365	COG0301	tRNA thio-modification
DYI95_RS06385	COG1686	Belongs to the peptidase S11 family
DYI95_RS06400	COG0460	homoserine dehydrogenase
DYI95_RS06405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYI95_RS06425	COG1489	DNA binding
DYI95_RS06435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DYI95_RS06440	COG0488	(ABC) transporter
DYI95_RS06445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI95_RS06450	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI95_RS06455	COG0697	spore germination
DYI95_RS06475	COG0372	Belongs to the citrate synthase family
DYI95_RS06480	COG1120	ATPase activity
DYI95_RS06485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYI95_RS06490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYI95_RS06495	COG1902	pentaerythritol trinitrate reductase activity
DYI95_RS06505	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DYI95_RS06520	COG1309	transcriptional regulator
DYI95_RS06525	COG0649	NAD binding
DYI95_RS06535	COG1744	ABC transporter substrate-binding protein PnrA-like
DYI95_RS06555	COG1132	(ABC) transporter
DYI95_RS06560	COG1132	(ABC) transporter
DYI95_RS06580	COG1408	metallophosphoesterase
DYI95_RS06590	COG1122	ATPase activity
DYI95_RS06595	COG4721	ABC-type cobalt transport system, permease component
DYI95_RS06600	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS06620	COG1984	allophanate hydrolase subunit 2
DYI95_RS06625	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DYI95_RS06630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DYI95_RS06640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYI95_RS06645	COG0601	transmembrane transport
DYI95_RS06650	COG0747	negative chemotaxis
DYI95_RS06655	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS06660	COG0444	Belongs to the ABC transporter superfamily
DYI95_RS06675	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS06705	COG0561	phosphatase activity
DYI95_RS06710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DYI95_RS06715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYI95_RS06720	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYI95_RS06730	COG2391	methyltransferase activity
DYI95_RS06740	COG5002	protein histidine kinase activity
DYI95_RS06745	COG0745	RESPONSE REGULATOR receiver
DYI95_RS06750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DYI95_RS06765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DYI95_RS06780	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS06785	COG1098	S1 RNA binding domain
DYI95_RS06795	COG1803	Methylglyoxal synthase
DYI95_RS06805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYI95_RS06805	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS06810	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS06825	COG2197	response regulator
DYI95_RS06830	COG4585	Histidine kinase
DYI95_RS06840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DYI95_RS06865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DYI95_RS06870	COG0805	protein transport
DYI95_RS06875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYI95_RS06885	COG0612	Peptidase, M16
DYI95_RS06890	COG0612	Peptidase, M16
DYI95_RS06900	COG1609	Transcriptional regulator
DYI95_RS06910	COG0745	RESPONSE REGULATOR receiver
DYI95_RS06915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI95_RS06920	COG0511	ligase activity, forming carbon-carbon bonds
DYI95_RS06925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DYI95_RS06935	COG0302	gtp cyclohydrolase
DYI95_RS06955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DYI95_RS06965	COG0277	FAD linked oxidase domain protein
DYI95_RS06970	COG0247	lactate metabolic process
DYI95_RS06980	COG0277	FAD linked oxidase domain protein
DYI95_RS06985	COG0584	glycerophosphoryl diester phosphodiesterase
DYI95_RS06995	COG0300	oxidoreductase activity
DYI95_RS07000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DYI95_RS07005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DYI95_RS07010	COG2080	2 iron, 2 sulfur cluster binding
DYI95_RS07040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DYI95_RS07060	COG1309	transcriptional regulator
DYI95_RS07080	COG0697	spore germination
DYI95_RS07085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DYI95_RS07090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DYI95_RS07090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DYI95_RS07100	COG0151	Belongs to the GarS family
DYI95_RS07105	COG0138	bifunctional purine biosynthesis protein purh
DYI95_RS07115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DYI95_RS07120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DYI95_RS07140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DYI95_RS07145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYI95_RS07150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DYI95_RS07165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYI95_RS07170	COG0316	Belongs to the HesB IscA family
DYI95_RS07175	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS07180	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS07180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYI95_RS07190	COG1126	abc transporter atp-binding protein
DYI95_RS07195	COG0765	amino acid transport
DYI95_RS07200	COG4597	amino acid ABC transporter
DYI95_RS07205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYI95_RS07210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DYI95_RS07215	COG2154	pterin-4-alpha-carbinolamine dehydratase
DYI95_RS07225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYI95_RS07230	COG1090	epimerase
DYI95_RS07265	COG0159	tryptophan synthase activity
DYI95_RS07270	COG0133	tryptophan synthase activity
DYI95_RS07275	COG0135	phosphoribosylanthranilate isomerase activity
DYI95_RS07280	COG0134	indole-3-glycerol-phosphate synthase activity
DYI95_RS07285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYI95_RS07295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DYI95_RS07300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYI95_RS07310	COG0303	'Molybdopterin
DYI95_RS07315	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DYI95_RS07330	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DYI95_RS07345	COG1414	Transcriptional regulator
DYI95_RS07350	COG0747	negative chemotaxis
DYI95_RS07355	COG0601	transmembrane transport
DYI95_RS07360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYI95_RS07365	COG2059	Chromate
DYI95_RS07375	COG0444	Belongs to the ABC transporter superfamily
DYI95_RS07380	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS07385	COG0549	Belongs to the carbamate kinase family
DYI95_RS07400	COG2233	PERMEase
DYI95_RS07405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYI95_RS07410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYI95_RS07430	COG2508	Transcriptional regulator
DYI95_RS07435	COG1024	Enoyl-CoA hydratase
DYI95_RS07440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI95_RS07445	COG0477	Major facilitator Superfamily
DYI95_RS07450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYI95_RS07450	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS07455	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYI95_RS07515	COG1216	Glycosyl transferase, family 2
DYI95_RS07520	COG0489	protein tyrosine kinase activity
DYI95_RS07525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYI95_RS07535	COG1276	copper resistance
DYI95_RS07545	COG0535	radical SAM domain protein
DYI95_RS07550	COG2132	Multicopper oxidase
DYI95_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
DYI95_RS07580	COG1063	alcohol dehydrogenase
DYI95_RS07590	COG1309	transcriptional regulator
DYI95_RS07595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DYI95_RS07630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYI95_RS07640	COG2313	pseudouridylate synthase activity
DYI95_RS07650	COG0542	response to heat
DYI95_RS07655	COG1940	carbohydrate kinase activity
DYI95_RS07665	COG1175	transmembrane transport
DYI95_RS07670	COG0395	ABC-type sugar transport system, permease component
DYI95_RS07675	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DYI95_RS07740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYI95_RS07760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYI95_RS07765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYI95_RS07775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DYI95_RS07780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DYI95_RS07785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI95_RS07790	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DYI95_RS07795	COG2217	Heavy metal translocating P-type atpase
DYI95_RS07800	COG1937	Protein conserved in bacteria
DYI95_RS07845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYI95_RS07850	COG1937	Protein conserved in bacteria
DYI95_RS07855	COG2217	Heavy metal translocating P-type atpase
DYI95_RS07870	COG0501	Belongs to the peptidase M48B family
DYI95_RS07890	COG2205	protein histidine kinase activity
DYI95_RS07895	COG0745	RESPONSE REGULATOR receiver
DYI95_RS07910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI95_RS07935	COG0438	transferase activity, transferring glycosyl groups
DYI95_RS07940	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI95_RS07970	COG5002	protein histidine kinase activity
DYI95_RS07980	COG0745	RESPONSE REGULATOR receiver
DYI95_RS07985	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS08005	COG0745	RESPONSE REGULATOR receiver
DYI95_RS08010	COG2205	protein histidine kinase activity
DYI95_RS08045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DYI95_RS08050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DYI95_RS08070	COG0626	cystathionine gamma-synthase activity
DYI95_RS08085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DYI95_RS08090	COG1335	isochorismatase
DYI95_RS08095	COG0745	RESPONSE REGULATOR receiver
DYI95_RS08100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYI95_RS08105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DYI95_RS08110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DYI95_RS08125	COG2376	Dihydroxyacetone kinase
DYI95_RS08130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DYI95_RS08140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYI95_RS08145	COG0704	Plays a role in the regulation of phosphate uptake
DYI95_RS08150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DYI95_RS08155	COG0581	inorganic phosphate transmembrane transporter activity
DYI95_RS08160	COG0573	inorganic phosphate transmembrane transporter activity
DYI95_RS08170	COG5002	protein histidine kinase activity
DYI95_RS08180	COG1993	acr, cog1993
DYI95_RS08185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYI95_RS08195	COG0114	fumarate hydratase activity
DYI95_RS08220	COG2323	membrane
DYI95_RS08225	COG2131	deaminase
DYI95_RS08235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYI95_RS08240	COG0321	lipoyl(octanoyl) transferase activity
DYI95_RS08245	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYI95_RS08260	COG3377	Domain of unknown function (DUF1805)
DYI95_RS08265	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DYI95_RS08285	COG0022	dehydrogenase e1 component
DYI95_RS08310	COG0477	Major facilitator Superfamily
DYI95_RS08325	COG0477	Major facilitator Superfamily
DYI95_RS08330	COG0109	protoheme IX farnesyltransferase activity
DYI95_RS08340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYI95_RS08345	COG0473	3-isopropylmalate dehydrogenase activity
DYI95_RS08350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DYI95_RS08355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYI95_RS08370	COG1363	Peptidase, m42
DYI95_RS08385	COG1263	PTS System
DYI95_RS08385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DYI95_RS08385	COG2190	(PTS) system
DYI95_RS08415	COG1827	regulation of RNA biosynthetic process
DYI95_RS08435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYI95_RS08440	COG0601	transmembrane transport
DYI95_RS08445	COG4166	transmembrane transport
DYI95_RS08455	COG0019	diaminopimelate decarboxylase activity
DYI95_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS08520	COG1139	Iron-sulfur cluster binding protein
DYI95_RS08525	COG0745	RESPONSE REGULATOR receiver
DYI95_RS08530	COG2205	protein histidine kinase activity
DYI95_RS08535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DYI95_RS08540	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DYI95_RS08545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DYI95_RS08565	COG1725	Transcriptional regulator
DYI95_RS08600	COG0730	response to heat
DYI95_RS08630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYI95_RS08645	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DYI95_RS08655	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DYI95_RS08670	COG0409	Hydrogenase expression formation protein
DYI95_RS08725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DYI95_RS08730	COG0375	protein maturation
DYI95_RS08745	COG0028	Belongs to the TPP enzyme family
DYI95_RS08760	COG0083	homoserine kinase activity
DYI95_RS08765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYI95_RS08780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI95_RS08805	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DYI95_RS08805	COG3608	succinylglutamate desuccinylase aspartoacylase
DYI95_RS08815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYI95_RS08830	COG2318	DinB family
DYI95_RS08860	COG2224	Isocitrate lyase
DYI95_RS08865	COG0440	acetolactate synthase activity
DYI95_RS08870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYI95_RS08875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYI95_RS08880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYI95_RS08885	COG0066	3-isopropylmalate dehydratase activity
DYI95_RS08890	COG0473	3-isopropylmalate dehydrogenase activity
DYI95_RS08895	COG0129	dihydroxy-acid dehydratase activity
DYI95_RS08900	COG0028	Belongs to the TPP enzyme family
DYI95_RS08905	COG4608	Belongs to the ABC transporter superfamily
DYI95_RS08920	COG0601	transmembrane transport
DYI95_RS08925	COG0747	negative chemotaxis
DYI95_RS08930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYI95_RS08945	COG1122	ATPase activity
DYI95_RS08950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DYI95_RS08960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYI95_RS08965	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS08970	COG0473	3-isopropylmalate dehydrogenase activity
DYI95_RS08980	COG1012	belongs to the aldehyde dehydrogenase family
DYI95_RS08985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYI95_RS09030	COG1414	Transcriptional regulator
DYI95_RS09065	COG2030	dehydratase
DYI95_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
DYI95_RS09075	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DYI95_RS09085	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS09095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYI95_RS09110	COG2030	dehydratase
DYI95_RS09135	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS09160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DYI95_RS09165	COG0697	spore germination
DYI95_RS09200	COG1960	acyl-CoA dehydrogenase activity
DYI95_RS09205	COG0318	PFAM AMP-dependent synthetase and ligase
DYI95_RS09220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DYI95_RS09225	COG1714	RDD family
DYI95_RS09240	COG0697	spore germination
DYI95_RS09250	COG2031	fatty acid transporter
DYI95_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS09275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYI95_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
DYI95_RS09310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI95_RS09335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DYI95_RS09345	COG1131	(ABC) transporter
DYI95_RS09360	COG0714	Associated with various cellular activities
DYI95_RS09385	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DYI95_RS09385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYI95_RS09390	COG1131	(ABC) transporter
DYI95_RS09405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DYI95_RS09445	COG3443	Belongs to the bacterial solute-binding protein 9 family
DYI95_RS09445	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYI95_RS09455	COG1121	(ABC) transporter
DYI95_RS09460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYI95_RS09485	COG3842	ATPase activity
DYI95_RS09490	COG0395	ABC-type sugar transport system, permease component
DYI95_RS09495	COG1175	transmembrane transport
DYI95_RS09505	COG1653	transport
DYI95_RS09530	COG5001	Diguanylate cyclase
DYI95_RS09565	COG4152	abc transporter atp-binding protein
DYI95_RS09620	COG1247	-acetyltransferase
DYI95_RS09650	COG1131	(ABC) transporter
DYI95_RS09660	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYI95_RS09675	COG1111	helicase
DYI95_RS09675	COG1205	dead DEAH box helicase
DYI95_RS09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI95_RS09730	COG3959	Transketolase, thiamine diphosphate binding domain
DYI95_RS09735	COG3958	Transketolase
DYI95_RS09745	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYI95_RS09750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYI95_RS09755	COG1121	(ABC) transporter
DYI95_RS09780	COG0351	phosphomethylpyrimidine kinase
DYI95_RS09780	COG0352	thiamine-phosphate diphosphorylase activity
DYI95_RS09790	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DYI95_RS09795	COG0352	thiamine-phosphate diphosphorylase activity
DYI95_RS09800	COG2814	Major facilitator Superfamily
DYI95_RS09815	COG3842	ATPase activity
DYI95_RS09835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DYI95_RS09840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYI95_RS09840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYI95_RS09845	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DYI95_RS09860	COG0577	efflux transmembrane transporter activity
DYI95_RS09870	COG1136	(ABC) transporter
DYI95_RS09870	COG0577	efflux transmembrane transporter activity
DYI95_RS09880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DYI95_RS09885	COG2079	MmgE PrpD family protein
DYI95_RS09890	COG0372	Belongs to the citrate synthase family
DYI95_RS09925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYI95_RS09925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYI95_RS09930	COG0584	glycerophosphoryl diester phosphodiesterase
DYI95_RS09935	COG0737	Belongs to the 5'-nucleotidase family
DYI95_RS09945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI95_RS09955	COG0604	alcohol dehydrogenase
DYI95_RS09965	COG0366	Alpha amylase catalytic
DYI95_RS09970	COG0395	ABC-type sugar transport system, permease component
DYI95_RS09975	COG1175	transmembrane transport
DYI95_RS09985	COG3842	ATPase activity
DYI95_RS09995	COG0861	Integral membrane protein TerC family
DYI95_RS10010	COG3395	kinase activity
DYI95_RS10015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DYI95_RS10020	COG2610	gluconate transmembrane transporter activity
DYI95_RS10035	COG0564	pseudouridine synthase activity
DYI95_RS10040	COG0822	iron-sulfur transferase activity
DYI95_RS10045	COG2897	thiosulfate sulfurtransferase activity
DYI95_RS10060	COG3949	Membrane
DYI95_RS10065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYI95_RS10070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DYI95_RS10090	COG1278	Cold shock
DYI95_RS10095	COG1252	NADH dehydrogenase
DYI95_RS10125	COG0012	GTP binding
DYI95_RS10135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DYI95_RS10145	COG0719	Fe-S assembly protein
DYI95_RS10155	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DYI95_RS10160	COG0284	orotidine-5'-phosphate decarboxylase activity
DYI95_RS10165	COG0167	dihydroorotate dehydrogenase activity
DYI95_RS10180	COG0505	Belongs to the CarA family
DYI95_RS10190	COG0540	Belongs to the ATCase OTCase family
DYI95_RS10195	COG2217	Heavy metal translocating P-type atpase
DYI95_RS10200	COG0640	Transcriptional regulator
DYI95_RS10215	COG1376	ErfK ybiS ycfS ynhG family protein
DYI95_RS10220	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI95_RS10240	COG0785	Cytochrome C biogenesis protein
DYI95_RS10270	COG0681	Belongs to the peptidase S26 family
DYI95_RS10320	COG0037	tRNA processing
DYI95_RS10335	COG2045	Belongs to the ComB family
DYI95_RS10340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DYI95_RS10345	COG1138	Cytochrome C-type biogenesis protein
DYI95_RS10350	COG4235	cytochrome complex assembly
DYI95_RS10350	COG3088	subunit of a heme lyase
DYI95_RS10355	COG4347	Protein of unknown function (DUF1405)
DYI95_RS10360	COG3773	Cell wall hydrolase
DYI95_RS10360	COG3409	Peptidoglycan-binding domain 1 protein
DYI95_RS10365	COG1078	dGTPase activity
DYI95_RS10370	COG0314	molybdopterin synthase activity
DYI95_RS10375	COG3639	organic phosphonate transmembrane transporter activity
DYI95_RS10380	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DYI95_RS10385	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DYI95_RS10395	COG3546	catalase activity
DYI95_RS10405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYI95_RS10420	COG0277	FAD linked oxidase domain protein
DYI95_RS10435	COG2201	protein-glutamate methylesterase activity
DYI95_RS10440	COG0840	transmembrane signaling receptor activity
DYI95_RS10445	COG0835	chemotaxis
DYI95_RS10450	COG0643	Histidine kinase
DYI95_RS10450	COG2198	Histidine kinase
DYI95_RS10455	COG2201	protein-glutamate methylesterase activity
DYI95_RS10475	COG2358	TRAP transporter, solute receptor (TAXI family
DYI95_RS10480	COG1363	Peptidase, m42
DYI95_RS10495	COG2226	methyltransferase
DYI95_RS10510	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DYI95_RS10535	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYI95_RS10555	COG2197	response regulator
DYI95_RS10560	COG4585	Histidine kinase
DYI95_RS10570	COG1511	domain protein
DYI95_RS10570	COG0842	Transport permease protein
DYI95_RS10575	COG1131	(ABC) transporter
DYI95_RS10605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYI95_RS10610	COG0358	DNA primase activity
DYI95_RS10615	COG0183	Belongs to the thiolase family
DYI95_RS10620	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYI95_RS10625	COG1024	Enoyl-CoA hydratase
DYI95_RS10630	COG2151	metal-sulfur cluster biosynthetic enzyme
DYI95_RS10645	COG3396	Phenylacetate-CoA oxygenase
DYI95_RS10650	COG1309	transcriptional regulator
DYI95_RS10700	COG3279	Response regulator of the LytR AlgR family
DYI95_RS10705	COG3275	phosphorelay sensor kinase activity
DYI95_RS10710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYI95_RS10715	COG0598	Magnesium transport protein CorA
DYI95_RS10745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DYI95_RS10750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DYI95_RS10760	COG0574	Belongs to the PEP-utilizing enzyme family
DYI95_RS10760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYI95_RS10765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DYI95_RS10770	COG0751	glycine-tRNA ligase activity
DYI95_RS10775	COG0752	glycyl-tRNA synthetase alpha subunit
DYI95_RS10785	COG1381	Involved in DNA repair and RecF pathway recombination
DYI95_RS10790	COG2239	Acts as a magnesium transporter
DYI95_RS10795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYI95_RS10800	COG1470	cell adhesion involved in biofilm formation
DYI95_RS10805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DYI95_RS10810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DYI95_RS10815	COG1480	7TM receptor with intracellular HD hydrolase
DYI95_RS10820	COG1702	phosphate starvation-inducible protein PhoH
DYI95_RS10845	COG1030	water channel activity
DYI95_RS10855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DYI95_RS10860	COG0537	adenosine 5'-monophosphoramidase activity
DYI95_RS10865	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYI95_RS10870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DYI95_RS10875	COG2264	protein methyltransferase activity
DYI95_RS10880	COG0484	heat shock protein binding
DYI95_RS10885	COG0443	Heat shock 70 kDa protein
DYI95_RS10890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYI95_RS10895	COG1420	regulation of RNA biosynthetic process
DYI95_RS10905	COG0481	GTPase activity
DYI95_RS10925	COG0268	Binds directly to 16S ribosomal RNA
DYI95_RS10930	COG1466	dna polymerase III delta subunit
DYI95_RS10935	COG2333	competence protein COMEC
DYI95_RS10935	COG0658	competence protein
DYI95_RS10945	COG0495	leucyl-tRNA aminoacylation
DYI95_RS10955	COG0799	negative regulation of ribosome biogenesis
DYI95_RS10960	COG1316	TRANSCRIPTIONal
DYI95_RS10965	COG1713	HD superfamily hydrolase involved in NAD metabolism
DYI95_RS10970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DYI95_RS10975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYI95_RS10985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DYI95_RS10990	COG2868	ribosomal protein
DYI95_RS10995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DYI95_RS11000	COG1530	ribonuclease E activity
DYI95_RS11010	COG4942	peptidase
DYI95_RS11015	COG0772	Belongs to the SEDS family
DYI95_RS11020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DYI95_RS11025	COG2894	cell division
DYI95_RS11030	COG0850	regulation of cytokinetic process
DYI95_RS11045	COG1792	Involved in formation and maintenance of cell shape
DYI95_RS11050	COG1077	Cell shape determining protein MreB Mrl
DYI95_RS11055	COG2003	Belongs to the UPF0758 family
DYI95_RS11060	COG0424	maF-like protein
DYI95_RS11070	COG0525	valine-tRNA ligase activity
DYI95_RS11075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DYI95_RS11080	COG0470	DNA polymerase III
DYI95_RS11080	COG1067	ATP-dependent peptidase activity
DYI95_RS11085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYI95_RS11090	COG0740	serine-type endopeptidase activity
DYI95_RS11095	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYI95_RS11110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DYI95_RS11155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYI95_RS11165	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DYI95_RS11170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYI95_RS11180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DYI95_RS11185	COG0557	exoribonuclease II activity
DYI95_RS11190	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DYI95_RS11195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYI95_RS11200	COG0148	phosphopyruvate hydratase activity
DYI95_RS11205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DYI95_RS11210	COG0149	triose-phosphate isomerase activity
DYI95_RS11215	COG0126	phosphoglycerate kinase activity
DYI95_RS11230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DYI95_RS11245	COG1012	belongs to the aldehyde dehydrogenase family
DYI95_RS11250	COG0735	belongs to the Fur family
DYI95_RS11285	COG0003	Pfam Anion-transporting ATPase
DYI95_RS11290	COG0003	Pfam Anion-transporting ATPase
DYI95_RS11300	COG1966	Carbon starvation protein
DYI95_RS11310	COG0439	Biotin carboxylase
DYI95_RS11315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DYI95_RS11320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DYI95_RS11325	COG0101	tRNA pseudouridine synthase activity
DYI95_RS11330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DYI95_RS11335	COG1122	ATPase activity
DYI95_RS11340	COG1122	ATPase activity
DYI95_RS11345	COG0203	ribosomal protein L17
DYI95_RS11350	COG0202	RNA polymerase activity
DYI95_RS11355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DYI95_RS11365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYI95_RS11370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DYI95_RS11385	COG0563	adenylate kinase activity
DYI95_RS11390	COG0201	protein transport
DYI95_RS11395	COG0200	Binds to the 23S rRNA
DYI95_RS11400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DYI95_RS11405	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DYI95_RS11410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DYI95_RS11415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DYI95_RS11420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DYI95_RS11425	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DYI95_RS11430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DYI95_RS11435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DYI95_RS11440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DYI95_RS11445	COG0255	Belongs to the universal ribosomal protein uL29 family
DYI95_RS11450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DYI95_RS11455	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DYI95_RS11460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYI95_RS11465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DYI95_RS11470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYI95_RS11475	COG0089	rRNA binding
DYI95_RS11480	COG0088	Forms part of the polypeptide exit tunnel
DYI95_RS11485	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DYI95_RS11490	COG0051	transcription antitermination factor activity, RNA binding
DYI95_RS11495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYI95_RS11500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYI95_RS11505	COG0049	tRNA binding
DYI95_RS11510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYI95_RS11515	COG1358	cellular component organization or biogenesis
DYI95_RS11520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DYI95_RS11525	COG0085	RNA polymerase activity
DYI95_RS11530	COG0222	ribosome binding
DYI95_RS11535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DYI95_RS11540	COG0081	regulation of translation
DYI95_RS11545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DYI95_RS11550	COG0250	Participates in transcription elongation, termination and antitermination
DYI95_RS11555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYI95_RS11565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DYI95_RS11600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYI95_RS11605	COG0215	cysteine-tRNA ligase activity
DYI95_RS11610	COG1045	serine acetyltransferase
DYI95_RS11615	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYI95_RS11620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DYI95_RS11620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DYI95_RS11625	COG4956	integral membrane protein (PIN domain superfamily)
DYI95_RS11630	COG1329	Transcriptional regulator
DYI95_RS11640	COG2046	Belongs to the sulfate adenylyltransferase family
DYI95_RS11645	COG0175	sulfate reduction
DYI95_RS11650	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DYI95_RS11655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DYI95_RS11660	COG0542	response to heat
DYI95_RS11665	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DYI95_RS11680	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DYI95_RS11685	COG1324	tolerance protein
DYI95_RS11690	COG1522	sequence-specific DNA binding
DYI95_RS11695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DYI95_RS11700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYI95_RS11720	COG0616	signal peptide processing
DYI95_RS11725	COG0504	CTP synthase activity
DYI95_RS11730	COG0018	arginyl-trna synthetase
DYI95_RS11735	COG0010	Belongs to the arginase family
DYI95_RS11740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DYI95_RS11750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DYI95_RS11755	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DYI95_RS11760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYI95_RS11770	COG0739	heme binding
DYI95_RS11770	COG0741	lytic transglycosylase activity
DYI95_RS11770	COG1196	nuclear chromosome segregation
DYI95_RS11795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYI95_RS11800	COG0305	Participates in initiation and elongation during chromosome replication
DYI95_RS11805	COG0359	binds to the 23S rRNA
DYI95_RS11815	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DYI95_RS11820	COG0629	single-stranded DNA binding
DYI95_RS11825	COG0360	Binds together with S18 to 16S ribosomal RNA
DYI95_RS11830	COG4481	Protein conserved in bacteria
DYI95_RS11855	COG0559	Belongs to the binding-protein-dependent transport system permease family
DYI95_RS11870	COG1597	lipid kinase activity
DYI95_RS11880	COG1475	DNA binding
DYI95_RS11885	COG1192	Involved in chromosome partitioning
DYI95_RS11890	COG1475	DNA binding
DYI95_RS11895	COG0357	Ribosomal RNA small subunit methyltransferase G
DYI95_RS11905	COG0706	membrane insertase activity
DYI95_RS11910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DYI95_RS11915	COG0594	ribonuclease P activity
DYI95_RS11920	COG0230	Belongs to the bacterial ribosomal protein bL34 family