locus-tag	class	description
THERJR_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THERJR_RS00015	COG0592	DNA-directed DNA polymerase activity
THERJR_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
THERJR_RS00040	COG0187	DNA topoisomerase II activity
THERJR_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
THERJR_RS00050	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
THERJR_RS00055	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
THERJR_RS00060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
THERJR_RS00065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
THERJR_RS00070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THERJR_RS00095	COG0590	tRNA wobble adenosine to inosine editing
THERJR_RS00105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THERJR_RS00110	COG1725	Transcriptional regulator
THERJR_RS00115	COG1131	(ABC) transporter
THERJR_RS00125	COG0793	Belongs to the peptidase S41A family
THERJR_RS00145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THERJR_RS00150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
THERJR_RS00160	COG5012	cobalamin binding
THERJR_RS00185	COG4145	pantothenate transmembrane transporter activity
THERJR_RS00195	COG4810	utilization protein
THERJR_RS00205	COG4303	Ethanolamine ammonia lyase large subunit
THERJR_RS00230	COG4820	ethanolamine utilization protein (EutJ)
THERJR_RS00240	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
THERJR_RS00245	COG4656	Part of a membrane complex involved in electron transport
THERJR_RS00270	COG1012	belongs to the aldehyde dehydrogenase family
THERJR_RS00270	COG1454	alcohol dehydrogenase
THERJR_RS00275	COG4869	propanediol catabolic process
THERJR_RS00285	COG0163	prenyltransferase activity
THERJR_RS00290	COG2207	Transcriptional regulator
THERJR_RS00295	COG5012	cobalamin binding
THERJR_RS00325	COG5012	cobalamin binding
THERJR_RS00335	COG0546	phosphoglycolate phosphatase activity
THERJR_RS00350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS00355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THERJR_RS00365	COG1564	THIamine pyrophosphokinase
THERJR_RS00380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THERJR_RS00385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THERJR_RS00390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
THERJR_RS00395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THERJR_RS00400	COG1605	Chorismate mutase
THERJR_RS00400	COG0077	Prephenate dehydratase
THERJR_RS00470	COG0741	lytic transglycosylase activity
THERJR_RS00480	COG1982	Orn Lys Arg decarboxylase major
THERJR_RS00485	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THERJR_RS00495	COG0470	DNA polymerase III
THERJR_RS00500	COG1774	PSP1 C-terminal conserved region
THERJR_RS00510	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
THERJR_RS00515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THERJR_RS00520	COG2002	toxin-antitoxin pair type II binding
THERJR_RS00530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THERJR_RS00530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THERJR_RS00535	COG0084	hydrolase, TatD family'
THERJR_RS00560	COG3583	domain protein
THERJR_RS00560	COG3584	3D domain protein
THERJR_RS00565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
THERJR_RS00580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THERJR_RS00600	COG0428	transporter
THERJR_RS00605	COG0835	chemotaxis
THERJR_RS00610	COG2198	Histidine kinase
THERJR_RS00610	COG0643	Histidine kinase
THERJR_RS00615	COG2201	protein-glutamate methylesterase activity
THERJR_RS00620	COG2201	protein-glutamate methylesterase activity
THERJR_RS00680	COG1376	ErfK ybiS ycfS ynhG family protein
THERJR_RS00685	COG4242	Belongs to the peptidase S51 family
THERJR_RS00695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
THERJR_RS00700	COG1802	Transcriptional regulator
THERJR_RS00710	COG2088	sporulation resulting in formation of a cellular spore
THERJR_RS00715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THERJR_RS00725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THERJR_RS00745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THERJR_RS00750	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
THERJR_RS00785	COG0348	domain, Protein
THERJR_RS00790	COG1187	pseudouridine synthase activity
THERJR_RS00795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
THERJR_RS00795	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
THERJR_RS00815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
THERJR_RS00815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
THERJR_RS00825	COG0348	domain, Protein
THERJR_RS00830	COG1309	transcriptional regulator
THERJR_RS00840	COG0739	heme binding
THERJR_RS00860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THERJR_RS00875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
THERJR_RS00915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THERJR_RS00925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THERJR_RS00930	COG0193	aminoacyl-tRNA hydrolase activity
THERJR_RS00940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THERJR_RS00950	COG2002	toxin-antitoxin pair type II binding
THERJR_RS00955	COG2244	polysaccharide biosynthetic process
THERJR_RS00960	COG3956	TIGRFAM MazG family protein
THERJR_RS00975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
THERJR_RS00980	COG2385	sporulation resulting in formation of a cellular spore
THERJR_RS01005	COG1098	S1 RNA binding domain
THERJR_RS01015	COG1309	transcriptional regulator
THERJR_RS01030	COG0248	Ppx GppA phosphatase
THERJR_RS01040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THERJR_RS01060	COG2208	phosphoserine phosphatase activity
THERJR_RS01070	COG0037	tRNA processing
THERJR_RS01075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THERJR_RS01080	COG0105	UTP biosynthetic process
THERJR_RS01090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THERJR_RS01100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
THERJR_RS01105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THERJR_RS01110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
THERJR_RS01120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THERJR_RS01125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THERJR_RS01130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
THERJR_RS01135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
THERJR_RS01140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
THERJR_RS01145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
THERJR_RS01170	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
THERJR_RS01170	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
THERJR_RS01175	COG1406	Chemotaxis phosphatase CheX
THERJR_RS01180	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
THERJR_RS01185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
THERJR_RS01200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THERJR_RS01205	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THERJR_RS01240	COG1053	succinate dehydrogenase
THERJR_RS01245	COG2508	Transcriptional regulator
THERJR_RS01250	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THERJR_RS01275	COG0556	nucleotide-excision repair
THERJR_RS01280	COG3869	Catalyzes the specific phosphorylation of arginine residues in
THERJR_RS01285	COG0542	response to heat
THERJR_RS01295	COG3344	reverse transcriptase
THERJR_RS01300	COG2208	phosphoserine phosphatase activity
THERJR_RS01305	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THERJR_RS01310	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
THERJR_RS01320	COG1329	Transcriptional regulator
THERJR_RS01325	COG4956	integral membrane protein (PIN domain superfamily)
THERJR_RS01330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
THERJR_RS01335	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THERJR_RS01350	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
THERJR_RS01365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
THERJR_RS01380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THERJR_RS01395	COG4086	secreted protein
THERJR_RS01410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THERJR_RS01415	COG1045	serine acetyltransferase
THERJR_RS01420	COG0215	cysteine-tRNA ligase activity
THERJR_RS01425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
THERJR_RS01435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THERJR_RS01440	COG3688	RNA-binding protein containing a PIN domain
THERJR_RS01475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THERJR_RS01495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
THERJR_RS01505	COG0250	Participates in transcription elongation, termination and antitermination
THERJR_RS01510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
THERJR_RS01515	COG0081	regulation of translation
THERJR_RS01520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THERJR_RS01525	COG0222	ribosome binding
THERJR_RS01535	COG0085	RNA polymerase activity
THERJR_RS01540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THERJR_RS01545	COG1358	cellular component organization or biogenesis
THERJR_RS01550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THERJR_RS01555	COG0049	tRNA binding
THERJR_RS01560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THERJR_RS01565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THERJR_RS01570	COG0051	transcription antitermination factor activity, RNA binding
THERJR_RS01575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
THERJR_RS01580	COG0088	Forms part of the polypeptide exit tunnel
THERJR_RS01585	COG0089	rRNA binding
THERJR_RS01590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THERJR_RS01595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THERJR_RS01600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
THERJR_RS01605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THERJR_RS01610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THERJR_RS01620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THERJR_RS01625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THERJR_RS01630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THERJR_RS01640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THERJR_RS01645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THERJR_RS01650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THERJR_RS01655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THERJR_RS01660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THERJR_RS01665	COG1841	ribosomal large subunit assembly
THERJR_RS01670	COG0200	Binds to the 23S rRNA
THERJR_RS01675	COG0201	protein transport
THERJR_RS01680	COG0024	Methionine aminopeptidase
THERJR_RS01690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
THERJR_RS01695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
THERJR_RS01700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THERJR_RS01705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THERJR_RS01710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THERJR_RS01715	COG0202	RNA polymerase activity
THERJR_RS01720	COG0203	ribosomal protein L17
THERJR_RS01725	COG1122	ATPase activity
THERJR_RS01730	COG1122	ATPase activity
THERJR_RS01735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
THERJR_RS01740	COG0101	tRNA pseudouridine synthase activity
THERJR_RS01745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THERJR_RS01765	COG0860	N-Acetylmuramoyl-L-alanine amidase
THERJR_RS01770	COG2078	PFAM AMMECR1 domain protein
THERJR_RS01770	COG3885	ferrous iron binding
THERJR_RS01790	COG0697	spore germination
THERJR_RS01795	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
THERJR_RS01810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
THERJR_RS01815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
THERJR_RS01830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THERJR_RS01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THERJR_RS01840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THERJR_RS01845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THERJR_RS01860	COG0165	Argininosuccinate lyase
THERJR_RS01865	COG0527	aspartate kinase activity
THERJR_RS01875	COG0129	dihydroxy-acid dehydratase activity
THERJR_RS01880	COG0028	Belongs to the TPP enzyme family
THERJR_RS01885	COG0440	acetolactate synthase activity
THERJR_RS01890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
THERJR_RS01895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THERJR_RS01900	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THERJR_RS01905	COG0066	3-isopropylmalate dehydratase activity
THERJR_RS01910	COG0473	3-isopropylmalate dehydrogenase activity
THERJR_RS01915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THERJR_RS01920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS01930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS01940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS01955	COG3856	small basic protein
THERJR_RS01965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
THERJR_RS01975	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
THERJR_RS01980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THERJR_RS02075	COG1361	Conserved repeat domain
THERJR_RS02140	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
THERJR_RS02175	COG2323	membrane
THERJR_RS02180	COG3459	Glycosyltransferase 36 associated
THERJR_RS02185	COG0653	protein targeting
THERJR_RS02190	COG3706	GGDEF domain
THERJR_RS02245	COG0537	adenosine 5'-monophosphoramidase activity
THERJR_RS02260	COG1592	Rubrerythrin
THERJR_RS02265	COG2033	superoxide reductase activity
THERJR_RS02275	COG0640	Transcriptional regulator
THERJR_RS02310	COG0640	Transcriptional regulator
THERJR_RS02320	COG2897	thiosulfate sulfurtransferase activity
THERJR_RS02325	COG2814	Major facilitator Superfamily
THERJR_RS02330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
THERJR_RS02335	COG1230	cation diffusion facilitator family transporter
THERJR_RS02340	COG0640	Transcriptional regulator
THERJR_RS02360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
THERJR_RS02385	COG1595	DNA-templated transcription, initiation
THERJR_RS02410	COG0640	Transcriptional regulator
THERJR_RS02415	COG0798	PFAM Bile acid sodium symporter
THERJR_RS02425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THERJR_RS02435	COG0586	Pfam SNARE associated Golgi protein
THERJR_RS02465	COG0728	peptidoglycan biosynthetic process
THERJR_RS02470	COG1595	DNA-templated transcription, initiation
THERJR_RS02485	COG0586	Pfam SNARE associated Golgi protein
THERJR_RS02530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
THERJR_RS02535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
THERJR_RS02545	COG2897	thiosulfate sulfurtransferase activity
THERJR_RS02550	COG0463	Glycosyl transferase, family 2
THERJR_RS02575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS02580	COG1116	anion transmembrane transporter activity
THERJR_RS02585	COG0583	DNA-binding transcription factor activity
THERJR_RS02595	COG0425	Belongs to the sulfur carrier protein TusA family
THERJR_RS02615	COG0583	DNA-binding transcription factor activity
THERJR_RS02660	COG2814	Major facilitator Superfamily
THERJR_RS02670	COG2226	methyltransferase
THERJR_RS02675	COG0427	acetyl-CoA hydrolase
THERJR_RS02680	COG0583	DNA-binding transcription factor activity
THERJR_RS02690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
THERJR_RS02735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
THERJR_RS02755	COG1309	transcriptional regulator
THERJR_RS02765	COG0247	lactate metabolic process
THERJR_RS02765	COG2181	nitrate reductase activity
THERJR_RS02770	COG1032	radical SAM domain protein
THERJR_RS02780	COG2890	protein-(glutamine-N5) methyltransferase activity
THERJR_RS02785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
THERJR_RS02790	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
THERJR_RS02795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THERJR_RS02800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THERJR_RS02805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
THERJR_RS02810	COG0789	Transcriptional regulator
THERJR_RS02820	COG2197	response regulator
THERJR_RS02880	COG1404	Belongs to the peptidase S8 family
THERJR_RS02915	COG1331	Highly conserved protein containing a thioredoxin domain
THERJR_RS02925	COG2814	Major facilitator Superfamily
THERJR_RS02945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
THERJR_RS02950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
THERJR_RS02955	COG1993	acr, cog1993
THERJR_RS02970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THERJR_RS03000	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
THERJR_RS03020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS03025	COG1116	anion transmembrane transporter activity
THERJR_RS03030	COG0010	Belongs to the arginase family
THERJR_RS03040	COG0831	urea catabolic process
THERJR_RS03050	COG0804	urea catabolic process
THERJR_RS03060	COG0830	nickel cation binding
THERJR_RS03065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
THERJR_RS03070	COG0829	nickel cation binding
THERJR_RS03080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
THERJR_RS03085	COG2972	Histidine kinase
THERJR_RS03090	COG3279	Response regulator of the LytR AlgR family
THERJR_RS03140	COG4869	propanediol catabolic process
THERJR_RS03155	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
THERJR_RS03170	COG4656	Part of a membrane complex involved in electron transport
THERJR_RS03180	COG0371	Dehydrogenase
THERJR_RS03185	COG1380	Effector of murein hydrolase LrgA
THERJR_RS03190	COG1346	cytolysis
THERJR_RS03195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THERJR_RS03225	COG0840	transmembrane signaling receptor activity
THERJR_RS03240	COG3858	chitin binding
THERJR_RS03240	COG1388	LysM domain
THERJR_RS03245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THERJR_RS03270	COG3275	phosphorelay sensor kinase activity
THERJR_RS03280	COG0835	chemotaxis
THERJR_RS03285	COG0736	holo-[acyl-carrier-protein] synthase activity
THERJR_RS03290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THERJR_RS03290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THERJR_RS03295	COG0617	tRNA 3'-terminal CCA addition
THERJR_RS03295	COG0517	IMP dehydrogenase activity
THERJR_RS03295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THERJR_RS03300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
THERJR_RS03310	COG3707	response regulator
THERJR_RS03340	COG0367	asparagine synthase
THERJR_RS03360	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS03365	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS03390	COG1598	PFAM Uncharacterised protein family UPF0150
THERJR_RS03425	COG3177	Filamentation induced by cAMP protein fic
THERJR_RS03445	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
THERJR_RS03450	COG0347	Belongs to the P(II) protein family
THERJR_RS03455	COG0347	Belongs to the P(II) protein family
THERJR_RS03480	COG1433	Dinitrogenase iron-molybdenum cofactor
THERJR_RS03480	COG0535	radical SAM domain protein
THERJR_RS03495	COG0725	ABC transporter, periplasmic molybdate-binding protein
THERJR_RS03500	COG4149	molybdate abc transporter
THERJR_RS03505	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
THERJR_RS03510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THERJR_RS03515	COG0004	ammonium transporteR
THERJR_RS03520	COG0347	Belongs to the P(II) protein family
THERJR_RS03530	COG0004	ammonium transporteR
THERJR_RS03535	COG0347	Belongs to the P(II) protein family
THERJR_RS03565	COG0067	glutamate synthase
THERJR_RS03575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THERJR_RS03580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THERJR_RS03590	COG0864	Transcriptional regulator
THERJR_RS03595	COG2337	Toxic component of a toxin-antitoxin (TA) module
THERJR_RS03600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
THERJR_RS03620	COG1228	amidohydrolase
THERJR_RS03630	COG0352	thiamine-phosphate diphosphorylase activity
THERJR_RS03630	COG0351	phosphomethylpyrimidine kinase
THERJR_RS03635	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THERJR_RS03640	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
THERJR_RS03645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
THERJR_RS03650	COG0802	atpase or kinase
THERJR_RS03655	COG1214	PFAM Peptidase M22, glycoprotease
THERJR_RS03660	COG0456	acetyltransferase
THERJR_RS03665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THERJR_RS03680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THERJR_RS03685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
THERJR_RS03705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
THERJR_RS03710	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THERJR_RS03725	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS03730	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS03740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS03760	COG0039	L-malate dehydrogenase activity
THERJR_RS03765	COG1921	L-seryl-tRNASec selenium transferase activity
THERJR_RS03770	COG0709	Synthesizes selenophosphate from selenide and ATP
THERJR_RS03775	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
THERJR_RS03780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
THERJR_RS03790	COG0303	'Molybdopterin
THERJR_RS03795	COG1910	domain protein
THERJR_RS03800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THERJR_RS03805	COG0315	cyclic pyranopterin monophosphate synthase activity
THERJR_RS03815	COG0521	Mo-molybdopterin cofactor biosynthetic process
THERJR_RS03820	COG3604	Transcriptional regulator
THERJR_RS03830	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
THERJR_RS03835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
THERJR_RS03840	COG0437	4 iron, 4 sulfur cluster binding
THERJR_RS03850	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS03850	COG0243	molybdopterin cofactor binding
THERJR_RS03860	COG0437	4 iron, 4 sulfur cluster binding
THERJR_RS03865	COG3301	Polysulphide reductase, NrfD
THERJR_RS03875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THERJR_RS03880	COG0459	protein refolding
THERJR_RS03905	COG1361	Conserved repeat domain
THERJR_RS03915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
THERJR_RS03925	COG0714	Associated with various cellular activities
THERJR_RS03940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
THERJR_RS03945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THERJR_RS03945	COG0519	Catalyzes the synthesis of GMP from XMP
THERJR_RS03955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS04000	COG4191	Histidine kinase
THERJR_RS04010	COG0444	Belongs to the ABC transporter superfamily
THERJR_RS04015	COG4608	Belongs to the ABC transporter superfamily
THERJR_RS04020	COG0747	negative chemotaxis
THERJR_RS04025	COG0601	transmembrane transport
THERJR_RS04030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THERJR_RS04095	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
THERJR_RS04125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THERJR_RS04135	COG0583	DNA-binding transcription factor activity
THERJR_RS04140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THERJR_RS04145	COG2252	PERMEase
THERJR_RS04150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THERJR_RS04155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
THERJR_RS04160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
THERJR_RS04165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
THERJR_RS04170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
THERJR_RS04175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
THERJR_RS04180	COG0138	bifunctional purine biosynthesis protein purh
THERJR_RS04185	COG0151	Belongs to the GarS family
THERJR_RS04190	COG4496	protein, YerC YecD
THERJR_RS04195	COG3290	protein histidine kinase activity
THERJR_RS04200	COG0124	histidyl-tRNA synthetase
THERJR_RS04215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THERJR_RS04220	COG0131	Imidazoleglycerol-phosphate dehydratase
THERJR_RS04230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
THERJR_RS04235	COG0107	imidazoleglycerol-phosphate synthase activity
THERJR_RS04240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
THERJR_RS04240	COG0140	phosphoribosyl-ATP diphosphatase activity
THERJR_RS04245	COG0840	transmembrane signaling receptor activity
THERJR_RS04245	COG3290	protein histidine kinase activity
THERJR_RS04255	COG0730	response to heat
THERJR_RS04270	COG0210	DNA helicase
THERJR_RS04280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THERJR_RS04285	COG1959	2 iron, 2 sulfur cluster binding
THERJR_RS04290	COG1271	oxidase subunit
THERJR_RS04295	COG1294	oxidase, subunit
THERJR_RS04300	COG1773	rubredoxin
THERJR_RS04300	COG1592	Rubrerythrin
THERJR_RS04315	COG1404	Belongs to the peptidase S8 family
THERJR_RS04320	COG1924	4 iron, 4 sulfur cluster binding
THERJR_RS04325	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
THERJR_RS04335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
THERJR_RS04340	COG0765	amino acid transport
THERJR_RS04380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THERJR_RS04385	COG0154	amidase activity
THERJR_RS04390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THERJR_RS04400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THERJR_RS04405	COG0538	isocitrate dehydrogenase activity
THERJR_RS04410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THERJR_RS04415	COG1079	Belongs to the binding-protein-dependent transport system permease family
THERJR_RS04420	COG4603	Belongs to the binding-protein-dependent transport system permease family
THERJR_RS04425	COG3845	ABC transporter
THERJR_RS04450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THERJR_RS04455	COG1543	Belongs to the glycosyl hydrolase 57 family
THERJR_RS04480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THERJR_RS04510	COG0464	growth
THERJR_RS04515	COG1404	Belongs to the peptidase S8 family
THERJR_RS04520	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
THERJR_RS04530	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
THERJR_RS04560	COG0058	SHG alpha-glucan phosphorylase activity
THERJR_RS04565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
THERJR_RS04570	COG0071	Belongs to the small heat shock protein (HSP20) family
THERJR_RS04575	COG0589	response to stress
THERJR_RS04585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THERJR_RS04585	COG0519	Catalyzes the synthesis of GMP from XMP
THERJR_RS04595	COG1566	PFAM secretion protein HlyD family protein
THERJR_RS04600	COG2814	Major facilitator Superfamily
THERJR_RS04605	COG1846	Transcriptional regulator
THERJR_RS04630	COG1136	(ABC) transporter
THERJR_RS04635	COG0719	Fe-S assembly protein
THERJR_RS04640	COG0443	Heat shock 70 kDa protein
THERJR_RS04655	COG0542	response to heat
THERJR_RS04660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
THERJR_RS04670	COG0446	pyridine nucleotide-disulphide oxidoreductase
THERJR_RS04685	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THERJR_RS04720	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
THERJR_RS04745	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS04750	COG0583	DNA-binding transcription factor activity
THERJR_RS04775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
THERJR_RS04780	COG2132	Multicopper oxidase
THERJR_RS04785	COG0288	reversible hydration of carbon dioxide
THERJR_RS04790	COG1595	DNA-templated transcription, initiation
THERJR_RS04810	COG0457	Tetratricopeptide repeat
THERJR_RS04810	COG0463	Glycosyl transferase, family 2
THERJR_RS04815	COG0463	Glycosyl transferase, family 2
THERJR_RS04815	COG0457	Tetratricopeptide repeat
THERJR_RS04820	COG0457	Tetratricopeptide repeat
THERJR_RS04820	COG0463	Glycosyl transferase, family 2
THERJR_RS04840	COG0463	Glycosyl transferase, family 2
THERJR_RS04840	COG0457	Tetratricopeptide repeat
THERJR_RS04860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
THERJR_RS04865	COG1971	Probably functions as a manganese efflux pump
THERJR_RS04870	COG0237	dephospho-CoA kinase activity
THERJR_RS04875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
THERJR_RS04880	COG4166	transmembrane transport
THERJR_RS04885	COG0601	transmembrane transport
THERJR_RS04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THERJR_RS04895	COG0444	Belongs to the ABC transporter superfamily
THERJR_RS04900	COG4608	Belongs to the ABC transporter superfamily
THERJR_RS04960	COG5012	cobalamin binding
THERJR_RS04965	COG5012	cobalamin binding
THERJR_RS04975	COG1410	methionine synthase
THERJR_RS04975	COG0646	methionine synthase
THERJR_RS04990	COG0523	cobalamin synthesis protein
THERJR_RS05045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS05050	COG1116	anion transmembrane transporter activity
THERJR_RS05060	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
THERJR_RS05065	COG1074	ATP-dependent DNA helicase activity
THERJR_RS05105	COG2949	membrane
THERJR_RS05170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS05215	COG0587	DNA-directed DNA polymerase activity
THERJR_RS05240	COG3848	Pyruvate phosphate dikinase
THERJR_RS05240	COG0574	Belongs to the PEP-utilizing enzyme family
THERJR_RS05245	COG2223	nitrite transmembrane transporter activity
THERJR_RS05255	COG3005	denitrification pathway
THERJR_RS05295	COG1376	ErfK ybiS ycfS ynhG family protein
THERJR_RS05325	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THERJR_RS05330	COG0010	Belongs to the arginase family
THERJR_RS05360	COG1191	sigma factor activity
THERJR_RS05365	COG3693	PFAM glycoside hydrolase, family 10
THERJR_RS05390	COG1111	helicase
THERJR_RS05390	COG1205	dead DEAH box helicase
THERJR_RS05395	COG1205	dead DEAH box helicase
THERJR_RS05395	COG1111	helicase
THERJR_RS05420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THERJR_RS05475	COG1196	nuclear chromosome segregation
THERJR_RS05495	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THERJR_RS05530	COG0778	Nitroreductase
THERJR_RS05535	COG2860	membrane
THERJR_RS05545	COG0444	Belongs to the ABC transporter superfamily
THERJR_RS05550	COG4608	Belongs to the ABC transporter superfamily
THERJR_RS05555	COG0747	negative chemotaxis
THERJR_RS05560	COG0601	transmembrane transport
THERJR_RS05565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THERJR_RS05585	COG0189	ligase activity
THERJR_RS05590	COG0189	ligase activity
THERJR_RS05595	COG0189	ligase activity
THERJR_RS05600	COG0189	ligase activity
THERJR_RS05620	COG0842	Transport permease protein
THERJR_RS05620	COG1129	ABC transporter
THERJR_RS05635	COG1454	alcohol dehydrogenase
THERJR_RS05635	COG1012	belongs to the aldehyde dehydrogenase family
THERJR_RS05655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THERJR_RS05670	COG3005	denitrification pathway
THERJR_RS05715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS05745	COG1333	cytochrome c biogenesis protein
THERJR_RS05750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS05755	COG1648	precorrin-2 dehydrogenase activity
THERJR_RS05755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
THERJR_RS05760	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
THERJR_RS05765	COG0181	hydroxymethylbilane synthase activity
THERJR_RS05775	COG0535	radical SAM domain protein
THERJR_RS05780	COG0113	porphobilinogen synthase activity
THERJR_RS05785	COG0535	radical SAM domain protein
THERJR_RS05790	COG1522	sequence-specific DNA binding
THERJR_RS05795	COG1522	sequence-specific DNA binding
THERJR_RS05800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
THERJR_RS05810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
THERJR_RS05815	COG0849	cell division
THERJR_RS05850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THERJR_RS05850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THERJR_RS05960	COG0586	Pfam SNARE associated Golgi protein
THERJR_RS05985	COG1181	Belongs to the D-alanine--D-alanine ligase family
THERJR_RS05990	COG0217	transcriptional regulatory protein
THERJR_RS06005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THERJR_RS06010	COG0632	four-way junction helicase activity
THERJR_RS06015	COG2255	four-way junction helicase activity
THERJR_RS06020	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THERJR_RS06030	COG1191	sigma factor activity
THERJR_RS06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THERJR_RS06040	COG2385	sporulation resulting in formation of a cellular spore
THERJR_RS06050	COG0697	spore germination
THERJR_RS06055	COG0697	spore germination
THERJR_RS06065	COG0765	amino acid transport
THERJR_RS06075	COG4869	propanediol catabolic process
THERJR_RS06085	COG0745	RESPONSE REGULATOR receiver
THERJR_RS06095	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
THERJR_RS06105	COG0343	queuine tRNA-ribosyltransferase activity
THERJR_RS06120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THERJR_RS06125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THERJR_RS06135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THERJR_RS06140	COG1490	D-aminoacyl-tRNA deacylase activity
THERJR_RS06145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THERJR_RS06165	COG0613	PHP domain protein
THERJR_RS06170	COG0569	domain protein
THERJR_RS06185	COG1388	LysM domain
THERJR_RS06200	COG0745	RESPONSE REGULATOR receiver
THERJR_RS06205	COG5002	protein histidine kinase activity
THERJR_RS06210	COG0247	lactate metabolic process
THERJR_RS06210	COG2181	nitrate reductase activity
THERJR_RS06265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THERJR_RS06270	COG0444	Belongs to the ABC transporter superfamily
THERJR_RS06275	COG4608	Belongs to the ABC transporter superfamily
THERJR_RS06280	COG2226	methyltransferase
THERJR_RS06290	COG4106	trans-aconitate 2-methyltransferase activity
THERJR_RS06310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THERJR_RS06315	COG4172	Belongs to the ABC transporter superfamily
THERJR_RS06320	COG0500	methyltransferase
THERJR_RS06330	COG0446	pyridine nucleotide-disulphide oxidoreductase
THERJR_RS06370	COG3693	PFAM glycoside hydrolase, family 10
THERJR_RS06405	COG0310	cobalt ion transport
THERJR_RS06415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
THERJR_RS06420	COG1122	ATPase activity
THERJR_RS06430	COG2249	NAD(P)H dehydrogenase (quinone) activity
THERJR_RS06440	COG0446	pyridine nucleotide-disulphide oxidoreductase
THERJR_RS06455	COG0598	Magnesium transport protein CorA
THERJR_RS06470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THERJR_RS06475	COG2137	regulation of response to DNA damage stimulus
THERJR_RS06480	COG1418	mRNA catabolic process
THERJR_RS06490	COG1692	metallophosphoesterase
THERJR_RS06495	COG2359	stage V sporulation protein S
THERJR_RS06505	COG0436	Aminotransferase
THERJR_RS06525	COG1113	amino acid transport
THERJR_RS06540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
THERJR_RS06575	COG1136	(ABC) transporter
THERJR_RS06575	COG0577	efflux transmembrane transporter activity
THERJR_RS06580	COG1136	(ABC) transporter
THERJR_RS06585	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
THERJR_RS06590	COG0298	carbon dioxide binding
THERJR_RS06595	COG0409	Hydrogenase expression formation protein
THERJR_RS06630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
THERJR_RS06650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THERJR_RS06655	COG0406	alpha-ribazole phosphatase activity
THERJR_RS06665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
THERJR_RS06685	COG0516	GMP reductase activity
THERJR_RS06685	COG0517	IMP dehydrogenase activity
THERJR_RS06695	COG0542	response to heat
THERJR_RS06715	COG0735	belongs to the Fur family
THERJR_RS06725	COG1129	ABC transporter
THERJR_RS06730	COG0730	response to heat
THERJR_RS06750	COG0772	Belongs to the SEDS family
THERJR_RS06760	COG0494	nUDIX hydrolase
THERJR_RS06790	COG2203	Gaf domain
THERJR_RS06790	COG2199	diguanylate cyclase activity
THERJR_RS06825	COG5002	protein histidine kinase activity
THERJR_RS06835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
THERJR_RS06845	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
THERJR_RS06855	COG2707	UPF0756 membrane protein
THERJR_RS06860	COG0052	Belongs to the universal ribosomal protein uS2 family
THERJR_RS06865	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THERJR_RS06870	COG0528	UMP kinase activity
THERJR_RS06875	COG0233	cytoplasmic translational termination
THERJR_RS06895	COG4589	Belongs to the CDS family
THERJR_RS06900	COG0628	permease
THERJR_RS06905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
THERJR_RS06910	COG0750	zinc metalloprotease
THERJR_RS06915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
THERJR_RS06920	COG0442	prolyl-tRNA aminoacylation
THERJR_RS06930	COG1285	pathogenesis
THERJR_RS06945	COG0779	Required for maturation of 30S ribosomal subunits
THERJR_RS06950	COG0195	Participates in both transcription termination and antitermination
THERJR_RS06955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
THERJR_RS06965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THERJR_RS06965	COG3064	Membrane
THERJR_RS06965	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THERJR_RS06965	COG3064	Membrane
THERJR_RS06970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THERJR_RS06975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THERJR_RS06980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THERJR_RS06985	COG0196	riboflavin kinase activity
THERJR_RS07000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THERJR_RS07005	COG1185	polyribonucleotide nucleotidyltransferase activity
THERJR_RS07010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
THERJR_RS07025	COG1388	LysM domain
THERJR_RS07025	COG3858	chitin binding
THERJR_RS07040	COG0726	polysaccharide deacetylase
THERJR_RS07045	COG1686	Belongs to the peptidase S11 family
THERJR_RS07050	COG0612	Peptidase, M16
THERJR_RS07065	COG1873	PFAM PRC-barrel domain
THERJR_RS07070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THERJR_RS07075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THERJR_RS07080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THERJR_RS07085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
THERJR_RS07090	COG0527	aspartate kinase activity
THERJR_RS07095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THERJR_RS07100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
THERJR_RS07105	COG0740	serine-type endopeptidase activity
THERJR_RS07115	COG1968	undecaprenyl-diphosphatase activity
THERJR_RS07120	COG1674	ftsk spoiiie
THERJR_RS07125	COG1744	ABC transporter substrate-binding protein PnrA-like
THERJR_RS07145	COG0463	Glycosyl transferase, family 2
THERJR_RS07150	COG1368	sulfuric ester hydrolase activity
THERJR_RS07160	COG3949	Membrane
THERJR_RS07170	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
THERJR_RS07175	COG1426	Protein conserved in bacteria
THERJR_RS07225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS07235	COG1666	GTP binding
THERJR_RS07255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS07260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
THERJR_RS07270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THERJR_RS07275	COG1546	Belongs to the CinA family
THERJR_RS07275	COG1058	Belongs to the CinA family
THERJR_RS07285	COG0513	Belongs to the DEAD box helicase family
THERJR_RS07300	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
THERJR_RS07305	COG0352	thiamine-phosphate diphosphorylase activity
THERJR_RS07320	COG1131	(ABC) transporter
THERJR_RS07330	COG1307	EDD domain protein, DegV family
THERJR_RS07335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THERJR_RS07395	COG0517	IMP dehydrogenase activity
THERJR_RS07400	COG4974	Belongs to the 'phage' integrase family
THERJR_RS07420	COG3328	transposase activity
THERJR_RS07425	COG2045	Belongs to the ComB family
THERJR_RS07430	COG1809	phosphosulfolactate synthase activity
THERJR_RS07435	COG2046	Belongs to the sulfate adenylyltransferase family
THERJR_RS07440	COG1116	anion transmembrane transporter activity
THERJR_RS07470	COG2814	Major facilitator Superfamily
THERJR_RS07505	COG2323	membrane
THERJR_RS07515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS07520	COG3679	Belongs to the UPF0342 family
THERJR_RS07525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THERJR_RS07540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THERJR_RS07545	COG2521	methyltransferase
THERJR_RS07545	COG2136	Putative SAM-dependent methyltransferase
THERJR_RS07550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THERJR_RS07555	COG1923	regulation of RNA biosynthetic process
THERJR_RS07565	COG0464	growth
THERJR_RS07570	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
THERJR_RS07605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
THERJR_RS07605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
THERJR_RS07610	COG0281	malic enzyme
THERJR_RS07640	COG1191	sigma factor activity
THERJR_RS07650	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
THERJR_RS07655	COG1776	CheC inhibitor of MCP methylation
THERJR_RS07665	COG0643	Histidine kinase
THERJR_RS07665	COG2198	Histidine kinase
THERJR_RS07670	COG2201	protein-glutamate methylesterase activity
THERJR_RS07685	COG1419	protein localization to endoplasmic reticulum
THERJR_RS07690	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THERJR_RS07695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THERJR_RS07700	COG1684	flagellar biosynthetic protein fliR
THERJR_RS07705	COG1987	bacterial-type flagellum assembly
THERJR_RS07710	COG1338	Plays a role in the flagellum-specific transport system
THERJR_RS07720	COG2201	protein-glutamate methylesterase activity
THERJR_RS07725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THERJR_RS07725	COG1776	CheC inhibitor of MCP methylation
THERJR_RS07730	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THERJR_RS07740	COG1582	Flagellar protein (FlbD)
THERJR_RS07755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
THERJR_RS07775	COG1157	protein secretion by the type III secretion system
THERJR_RS07785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THERJR_RS07790	COG1766	The M ring may be actively involved in energy transduction
THERJR_RS07795	COG1677	Flagellar hook-basal body complex protein FliE
THERJR_RS07815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THERJR_RS07820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THERJR_RS07825	COG4974	Belongs to the 'phage' integrase family
THERJR_RS07830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
THERJR_RS07835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
THERJR_RS07840	COG0758	DNA mediated transformation
THERJR_RS07840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THERJR_RS07845	COG1793	dna ligase
THERJR_RS07845	COG3285	dna ligase
THERJR_RS07850	COG1793	dna ligase
THERJR_RS07855	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
THERJR_RS07865	COG4191	Histidine kinase
THERJR_RS07875	COG3773	Cell wall hydrolase
THERJR_RS07885	COG0561	phosphatase activity
THERJR_RS07935	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
THERJR_RS07960	COG0860	N-Acetylmuramoyl-L-alanine amidase
THERJR_RS07975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
THERJR_RS07980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THERJR_RS07985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THERJR_RS07995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THERJR_RS08030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
THERJR_RS08030	COG0539	negative regulation of cytoplasmic translation
THERJR_RS08035	COG0204	Acyl-transferase
THERJR_RS08040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
THERJR_RS08065	COG0835	chemotaxis
THERJR_RS08070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THERJR_RS08075	COG0287	Prephenate dehydrogenase
THERJR_RS08080	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THERJR_RS08085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THERJR_RS08095	COG0133	tryptophan synthase activity
THERJR_RS08100	COG0135	phosphoribosylanthranilate isomerase activity
THERJR_RS08105	COG0134	indole-3-glycerol-phosphate synthase activity
THERJR_RS08110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THERJR_RS08115	COG0512	Glutamine amidotransferase of anthranilate synthase
THERJR_RS08140	COG2081	HI0933 family
THERJR_RS08145	COG1346	cytolysis
THERJR_RS08150	COG1380	Effector of murein hydrolase LrgA
THERJR_RS08160	COG1279	arginine transmembrane transporter activity
THERJR_RS08195	COG1418	mRNA catabolic process
THERJR_RS08215	COG1187	pseudouridine synthase activity
THERJR_RS08220	COG0700	Nucleoside recognition
THERJR_RS08225	COG2715	membrane protein required for spore maturation
THERJR_RS08230	COG0445	tRNA wobble uridine modification
THERJR_RS08235	COG3874	Sporulation protein YtfJ
THERJR_RS08250	COG0437	4 iron, 4 sulfur cluster binding
THERJR_RS08260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
THERJR_RS08270	COG0180	Tryptophanyl-tRNA synthetase
THERJR_RS08275	COG1994	Peptidase M50
THERJR_RS08280	COG3620	sequence-specific DNA binding
THERJR_RS08280	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THERJR_RS08280	COG0617	tRNA 3'-terminal CCA addition
THERJR_RS08285	COG0019	diaminopimelate decarboxylase activity
THERJR_RS08290	COG0393	Putative heavy-metal-binding
THERJR_RS08295	COG2340	Cysteine-rich secretory protein family
THERJR_RS08300	COG2076	Multidrug Resistance protein
THERJR_RS08305	COG0494	nUDIX hydrolase
THERJR_RS08315	COG1924	4 iron, 4 sulfur cluster binding
THERJR_RS08330	COG0697	spore germination
THERJR_RS08345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THERJR_RS08360	COG1191	sigma factor activity
THERJR_RS08365	COG2172	sigma factor antagonist activity
THERJR_RS08375	COG1686	Belongs to the peptidase S11 family
THERJR_RS08380	COG0531	amino acid
THERJR_RS08400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THERJR_RS08405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
THERJR_RS08410	COG4974	Belongs to the 'phage' integrase family
THERJR_RS08430	COG1379	DNA repair
THERJR_RS08440	COG2195	Cleaves the N-terminal amino acid of tripeptides
THERJR_RS08475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS08485	COG0280	phosphate acetyltransferase
THERJR_RS08490	COG3829	transcription factor binding
THERJR_RS08490	COG3290	protein histidine kinase activity
THERJR_RS08515	COG0745	RESPONSE REGULATOR receiver
THERJR_RS08520	COG0750	zinc metalloprotease
THERJR_RS08525	COG0497	DNA recombination
THERJR_RS08535	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
THERJR_RS08540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THERJR_RS08555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
THERJR_RS08560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
THERJR_RS08570	COG0142	geranyltranstransferase activity
THERJR_RS08575	COG1722	exodeoxyribonuclease VII activity
THERJR_RS08580	COG1570	exodeoxyribonuclease VII activity
THERJR_RS08595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THERJR_RS08600	COG0493	'glutamate synthase
THERJR_RS08610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THERJR_RS08620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
THERJR_RS08630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THERJR_RS08635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THERJR_RS08650	COG1302	Protein conserved in bacteria
THERJR_RS08655	COG0439	Biotin carboxylase
THERJR_RS08700	COG3854	ATPases associated with a variety of cellular activities
THERJR_RS08715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THERJR_RS08720	COG0006	proline dipeptidase activity
THERJR_RS08725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
THERJR_RS08730	COG0312	modulator of DNA gyrase
THERJR_RS08750	COG0328	RNA-DNA hybrid ribonuclease activity
THERJR_RS08755	COG0312	modulator of DNA gyrase
THERJR_RS08760	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THERJR_RS08765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
THERJR_RS08770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
THERJR_RS08810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
THERJR_RS08820	COG1459	type II secretion system
THERJR_RS08830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THERJR_RS08840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
THERJR_RS08850	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
THERJR_RS08855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THERJR_RS08870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THERJR_RS08890	COG0425	Belongs to the sulfur carrier protein TusA family
THERJR_RS08900	COG0805	protein transport
THERJR_RS08905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THERJR_RS08910	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
THERJR_RS08915	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
THERJR_RS08920	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
THERJR_RS08925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
THERJR_RS08930	COG2226	methyltransferase
THERJR_RS08950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
THERJR_RS08960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
THERJR_RS08965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THERJR_RS08965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THERJR_RS08975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THERJR_RS08975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THERJR_RS08980	COG2155	Conserved Protein
THERJR_RS08985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THERJR_RS08990	COG1162	GTPase activity
THERJR_RS08995	COG2815	serine threonine protein kinase
THERJR_RS08995	COG0515	serine threonine protein kinase
THERJR_RS09000	COG0768	penicillin binding
THERJR_RS09010	COG0631	protein serine/threonine phosphatase activity
THERJR_RS09025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THERJR_RS09030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THERJR_RS09030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
THERJR_RS09035	COG2738	Putative neutral zinc metallopeptidase
THERJR_RS09040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THERJR_RS09045	COG0242	peptide deformylase activity
THERJR_RS09050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THERJR_RS09070	COG1309	transcriptional regulator
THERJR_RS09090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THERJR_RS09095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THERJR_RS09100	COG1758	RNA polymerase activity
THERJR_RS09105	COG0194	GDP metabolic process
THERJR_RS09110	COG2052	Domain of unknown function (DUF370)
THERJR_RS09115	COG1561	YicC-like family, N-terminal region
THERJR_RS09120	COG1509	lysine 2,3-aminomutase activity
THERJR_RS09130	COG0436	Aminotransferase
THERJR_RS09135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
THERJR_RS09140	COG1293	RNA-binding protein homologous to eukaryotic snRNP
THERJR_RS09145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THERJR_RS09160	COG0437	4 iron, 4 sulfur cluster binding
THERJR_RS09175	COG0840	transmembrane signaling receptor activity
THERJR_RS09175	COG3290	protein histidine kinase activity
THERJR_RS09180	COG1217	gtp-binding protein TYPA
THERJR_RS09185	COG1683	Conserved Protein
THERJR_RS09200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
THERJR_RS09205	COG0284	orotidine-5'-phosphate decarboxylase activity
THERJR_RS09210	COG0167	dihydroorotate dehydrogenase activity
THERJR_RS09215	COG0543	2 iron, 2 sulfur cluster binding
THERJR_RS09220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THERJR_RS09225	COG0505	Belongs to the CarA family
THERJR_RS09230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THERJR_RS09235	COG0540	Belongs to the ATCase OTCase family
THERJR_RS09240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
THERJR_RS09255	COG0564	pseudouridine synthase activity
THERJR_RS09260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THERJR_RS09265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THERJR_RS09270	COG0778	Nitroreductase
THERJR_RS09305	COG3005	denitrification pathway
THERJR_RS09310	COG2197	response regulator
THERJR_RS09320	COG2848	UPF0210 protein
THERJR_RS09325	COG3830	Belongs to the UPF0237 family
THERJR_RS09345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS09355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THERJR_RS09365	COG3599	regulation of cell shape
THERJR_RS09370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THERJR_RS09375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
THERJR_RS09385	COG1193	negative regulation of DNA recombination
THERJR_RS09390	COG0826	peptidase U32
THERJR_RS09400	COG1796	DNA polymerase
THERJR_RS09400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THERJR_RS09405	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
THERJR_RS09410	COG0072	phenylalanine-tRNA ligase activity
THERJR_RS09410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THERJR_RS09415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THERJR_RS09420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THERJR_RS09425	COG0569	domain protein
THERJR_RS09430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
THERJR_RS09435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THERJR_RS09440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THERJR_RS09445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THERJR_RS09450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THERJR_RS09455	COG4399	Belongs to the UPF0754 family
THERJR_RS09495	COG1518	maintenance of DNA repeat elements
THERJR_RS09525	COG0768	penicillin binding
THERJR_RS09540	COG0826	peptidase U32
THERJR_RS09550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
THERJR_RS09560	COG2720	vancomycin resistance protein
THERJR_RS09565	COG3906	Belongs to the UPF0473 family
THERJR_RS09570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
THERJR_RS09575	COG0667	Aldo Keto reductase
THERJR_RS09580	COG4472	Bacterial protein of unknown function (DUF965)
THERJR_RS09590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THERJR_RS09600	COG0628	permease
THERJR_RS09615	COG0482	sulfurtransferase activity
THERJR_RS09620	COG0822	iron-sulfur transferase activity
THERJR_RS09630	COG1959	2 iron, 2 sulfur cluster binding
THERJR_RS09645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS09655	COG0735	belongs to the Fur family
THERJR_RS09665	COG1937	Protein conserved in bacteria
THERJR_RS09670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
THERJR_RS09675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THERJR_RS09680	COG0124	histidyl-tRNA synthetase
THERJR_RS09690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THERJR_RS09695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
THERJR_RS09700	COG2244	polysaccharide biosynthetic process
THERJR_RS09705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THERJR_RS09715	COG0302	gtp cyclohydrolase
THERJR_RS09740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THERJR_RS09745	COG1151	hydroxylamine reductase activity
THERJR_RS09760	COG0842	Transport permease protein
THERJR_RS09765	COG1131	(ABC) transporter
THERJR_RS09790	COG3852	Histidine kinase
THERJR_RS09835	COG1183	phosphatidylcholine synthase activity
THERJR_RS09840	COG0688	phosphatidylethanolamine metabolic process
THERJR_RS09845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
THERJR_RS09845	COG1199	ATP-dependent helicase activity
THERJR_RS09850	COG0432	Pfam Uncharacterised protein family UPF0047
THERJR_RS09865	COG0492	ferredoxin-NADP+ reductase activity
THERJR_RS09880	COG1694	Mazg nucleotide pyrophosphohydrolase
THERJR_RS09895	COG1694	Mazg nucleotide pyrophosphohydrolase
THERJR_RS09900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THERJR_RS09920	COG0582	viral genome integration into host DNA
THERJR_RS09930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THERJR_RS09960	COG0583	DNA-binding transcription factor activity
THERJR_RS09965	COG0563	adenylate kinase activity
THERJR_RS09970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
THERJR_RS09970	COG1773	rubredoxin
THERJR_RS09990	COG2719	SpoVR family
THERJR_RS09995	COG2718	Belongs to the UPF0229 family
THERJR_RS10000	COG2766	serine protein kinase
THERJR_RS10045	COG3328	transposase activity
THERJR_RS10100	COG3481	metal-dependent phosphohydrolase, HD sub domain
THERJR_RS10110	COG1361	Conserved repeat domain
THERJR_RS10120	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THERJR_RS10145	COG1567	CRISPR-associated RAMP protein, Csm4 family
THERJR_RS10150	COG1337	RAMP superfamily
THERJR_RS10165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THERJR_RS10180	COG0606	chelatase, subunit chli
THERJR_RS10185	COG0792	nuclease activity
THERJR_RS10190	COG1007	ATP synthesis coupled electron transport
THERJR_RS10195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS10200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THERJR_RS10215	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS10220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THERJR_RS10225	COG0649	NAD binding
THERJR_RS10230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS10235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS10240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS10255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THERJR_RS10260	COG0681	Belongs to the peptidase S26 family
THERJR_RS10265	COG0335	large ribosomal subunit rRNA binding
THERJR_RS10275	COG4752	Belongs to the RNA methyltransferase TrmD family
THERJR_RS10280	COG0336	Belongs to the RNA methyltransferase TrmD family
THERJR_RS10285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
THERJR_RS10295	COG1837	Belongs to the UPF0109 family
THERJR_RS10300	COG0228	four-way junction DNA binding
THERJR_RS10305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THERJR_RS10320	COG0306	phosphate transporter
THERJR_RS10330	COG0402	S-adenosylhomocysteine deaminase activity
THERJR_RS10340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
THERJR_RS10345	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THERJR_RS10350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THERJR_RS10355	COG0552	protein localization to endoplasmic reticulum
THERJR_RS10365	COG1196	nuclear chromosome segregation
THERJR_RS10375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
THERJR_RS10385	COG2226	methyltransferase
THERJR_RS10395	COG0571	ribonuclease III activity
THERJR_RS10400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THERJR_RS10410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THERJR_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
THERJR_RS10420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THERJR_RS10430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THERJR_RS10435	COG0416	fatty acid biosynthetic process
THERJR_RS10440	COG2030	dehydratase
THERJR_RS10445	COG1399	metal-binding, possibly nucleic acid-binding protein
THERJR_RS10450	COG0280	phosphate acetyltransferase
THERJR_RS10455	COG1323	Belongs to the UPF0348 family
THERJR_RS10460	COG3314	Sporulation integral membrane protein YlbJ
THERJR_RS10470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THERJR_RS10475	COG0742	ribosomal rna small subunit methyltransferase
THERJR_RS10485	COG0438	transferase activity, transferring glycosyl groups
THERJR_RS10490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
THERJR_RS10500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
THERJR_RS10505	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
THERJR_RS10535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THERJR_RS10540	COG1307	EDD domain protein, DegV family
THERJR_RS10545	COG1461	Dihydroxyacetone kinase
THERJR_RS10550	COG1302	Protein conserved in bacteria
THERJR_RS10560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THERJR_RS10565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
THERJR_RS10570	COG0622	Phosphoesterase
THERJR_RS10585	COG1376	ErfK ybiS ycfS ynhG family protein
THERJR_RS10595	COG1639	'signal transduction protein
THERJR_RS10610	COG0083	homoserine kinase activity
THERJR_RS10615	COG0460	homoserine dehydrogenase
THERJR_RS10620	COG4492	Belongs to the UPF0735 family
THERJR_RS10655	COG2302	S4 RNA-binding domain
THERJR_RS10665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
THERJR_RS10670	COG1799	cell septum assembly
THERJR_RS10675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
THERJR_RS10685	COG0704	Plays a role in the regulation of phosphate uptake
THERJR_RS10690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THERJR_RS10695	COG5002	protein histidine kinase activity
THERJR_RS10700	COG0745	RESPONSE REGULATOR receiver
THERJR_RS10705	COG1496	oxidoreductase activity
THERJR_RS10750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
THERJR_RS10765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THERJR_RS10780	COG1873	PFAM PRC-barrel domain
THERJR_RS10795	COG1191	sigma factor activity
THERJR_RS10800	COG1191	sigma factor activity
THERJR_RS10815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THERJR_RS10825	COG3856	small basic protein
THERJR_RS10835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
THERJR_RS10840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THERJR_RS10845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
THERJR_RS10850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THERJR_RS10855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THERJR_RS10860	COG0772	Belongs to the SEDS family
THERJR_RS10865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
THERJR_RS10870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THERJR_RS10875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THERJR_RS10880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
THERJR_RS10885	COG0768	penicillin binding
THERJR_RS10895	COG0275	rRNA processing
THERJR_RS10900	COG2001	Belongs to the MraZ family
THERJR_RS10915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THERJR_RS10940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
THERJR_RS10945	COG1489	DNA binding
THERJR_RS10965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THERJR_RS10985	COG3621	Patatin-like phospholipase
THERJR_RS10995	COG0288	reversible hydration of carbon dioxide
THERJR_RS11000	COG1136	(ABC) transporter
THERJR_RS11000	COG0577	efflux transmembrane transporter activity
THERJR_RS11005	COG1136	(ABC) transporter
THERJR_RS11010	COG1136	(ABC) transporter
THERJR_RS11010	COG0577	efflux transmembrane transporter activity
THERJR_RS11035	COG1283	sodium-dependent phosphate transmembrane transporter activity
THERJR_RS11040	COG3290	protein histidine kinase activity
THERJR_RS11040	COG0840	transmembrane signaling receptor activity
THERJR_RS11055	COG1686	Belongs to the peptidase S11 family
THERJR_RS11065	COG1533	DNA photolyase activity
THERJR_RS11085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THERJR_RS11175	COG3949	Membrane
THERJR_RS11180	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
THERJR_RS11190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
THERJR_RS11195	COG0303	'Molybdopterin
THERJR_RS11200	COG1546	Belongs to the CinA family
THERJR_RS11200	COG1058	Belongs to the CinA family
THERJR_RS11205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
THERJR_RS11210	COG4149	molybdate abc transporter
THERJR_RS11215	COG0725	ABC transporter, periplasmic molybdate-binding protein
THERJR_RS11225	COG3383	formate dehydrogenase (NAD+) activity
THERJR_RS11255	COG2217	Heavy metal translocating P-type atpase
THERJR_RS11260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
THERJR_RS11265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
THERJR_RS11275	COG0425	Belongs to the sulfur carrier protein TusA family
THERJR_RS11285	COG2046	Belongs to the sulfate adenylyltransferase family
THERJR_RS11295	COG1053	succinate dehydrogenase
THERJR_RS11300	COG0529	Catalyzes the synthesis of activated sulfate
THERJR_RS11305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
THERJR_RS11325	COG0800	Aldolase
THERJR_RS11335	COG3842	ATPase activity
THERJR_RS11340	COG4948	Mandelate Racemase Muconate Lactonizing
THERJR_RS11355	COG0395	ABC-type sugar transport system, permease component
THERJR_RS11360	COG1175	transmembrane transport
THERJR_RS11365	COG1653	transport
THERJR_RS11375	COG2414	aldehyde ferredoxin oxidoreductase
THERJR_RS11380	COG1414	Transcriptional regulator
THERJR_RS11395	COG2011	ABC-type metal ion transport system permease component
THERJR_RS11400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
THERJR_RS11405	COG2873	o-acetylhomoserine
THERJR_RS11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS11440	COG4555	ABC transporter
THERJR_RS11460	COG1138	Cytochrome C-type biogenesis protein
THERJR_RS11490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
THERJR_RS11505	COG1937	Protein conserved in bacteria
THERJR_RS11535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
THERJR_RS11540	COG2384	SAM-dependent methyltransferase
THERJR_RS11585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
THERJR_RS11590	COG0358	DNA primase activity
THERJR_RS11595	COG1671	Belongs to the UPF0178 family
THERJR_RS11600	COG0232	Belongs to the dGTPase family. Type 2 subfamily
THERJR_RS11610	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
THERJR_RS11615	COG1122	ATPase activity
THERJR_RS11635	COG0581	inorganic phosphate transmembrane transporter activity
THERJR_RS11640	COG0573	inorganic phosphate transmembrane transporter activity
THERJR_RS11645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
THERJR_RS11655	COG0745	RESPONSE REGULATOR receiver
THERJR_RS11660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THERJR_RS11660	COG0617	tRNA 3'-terminal CCA addition
THERJR_RS11660	COG0517	IMP dehydrogenase activity
THERJR_RS11685	COG0546	phosphoglycolate phosphatase activity
THERJR_RS11690	COG5001	Diguanylate cyclase
THERJR_RS11690	COG3300	MHYT domain
THERJR_RS11705	COG0205	6-phosphofructokinase activity
THERJR_RS11710	COG0825	malonyl-CoA metabolic process
THERJR_RS11715	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
THERJR_RS11740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
THERJR_RS11750	COG0011	TIGRFAM Protein of
THERJR_RS11755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THERJR_RS11760	COG0735	belongs to the Fur family
THERJR_RS11765	COG0438	transferase activity, transferring glycosyl groups
THERJR_RS11770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
THERJR_RS11780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THERJR_RS11785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THERJR_RS11790	COG1763	Mo-molybdopterin cofactor biosynthetic process
THERJR_RS11795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
THERJR_RS11805	COG0726	polysaccharide deacetylase
THERJR_RS11810	COG2226	methyltransferase
THERJR_RS11820	COG0517	IMP dehydrogenase activity
THERJR_RS11845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THERJR_RS11855	COG2720	vancomycin resistance protein
THERJR_RS11880	COG0297	glycogen (starch) synthase activity
THERJR_RS11905	COG0297	glycogen (starch) synthase activity
THERJR_RS11910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THERJR_RS11930	COG4224	UPF0291 protein
THERJR_RS11960	COG1752	Esterase of the alpha-beta hydrolase superfamily
THERJR_RS11975	COG0745	RESPONSE REGULATOR receiver
THERJR_RS11980	COG0745	RESPONSE REGULATOR receiver
THERJR_RS12000	COG0436	Aminotransferase
THERJR_RS12005	COG0037	tRNA processing
THERJR_RS12030	COG3546	catalase activity
THERJR_RS12065	COG0574	Belongs to the PEP-utilizing enzyme family
THERJR_RS12065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THERJR_RS12070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
THERJR_RS12075	COG0517	IMP dehydrogenase activity
THERJR_RS12080	COG0751	glycine-tRNA ligase activity
THERJR_RS12085	COG0752	glycyl-tRNA synthetase alpha subunit
THERJR_RS12095	COG1381	Involved in DNA repair and RecF pathway recombination
THERJR_RS12120	COG1250	3-hydroxyacyl-CoA dehydrogenase
THERJR_RS12140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
THERJR_RS12150	COG2239	Acts as a magnesium transporter
THERJR_RS12155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
THERJR_RS12160	COG0295	cytidine deaminase activity
THERJR_RS12165	COG1470	cell adhesion involved in biofilm formation
THERJR_RS12170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THERJR_RS12175	COG1480	7TM receptor with intracellular HD hydrolase
THERJR_RS12180	COG1702	phosphate starvation-inducible protein PhoH
THERJR_RS12200	COG4864	UPF0365 protein
THERJR_RS12205	COG1030	water channel activity
THERJR_RS12215	COG1704	LemA family
THERJR_RS12220	COG0631	protein serine/threonine phosphatase activity
THERJR_RS12275	COG0745	RESPONSE REGULATOR receiver
THERJR_RS12285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
THERJR_RS12290	COG0537	adenosine 5'-monophosphoramidase activity
THERJR_RS12295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS12300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
THERJR_RS12305	COG2264	protein methyltransferase activity
THERJR_RS12310	COG0484	heat shock protein binding
THERJR_RS12315	COG0443	Heat shock 70 kDa protein
THERJR_RS12320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THERJR_RS12330	COG1420	regulation of RNA biosynthetic process
THERJR_RS12335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THERJR_RS12340	COG0481	GTPase activity
THERJR_RS12350	COG0728	peptidoglycan biosynthetic process
THERJR_RS12370	COG0268	Binds directly to 16S ribosomal RNA
THERJR_RS12375	COG1466	dna polymerase III delta subunit
THERJR_RS12380	COG2333	competence protein COMEC
THERJR_RS12380	COG0658	competence protein
THERJR_RS12385	COG1555	photosystem II stabilization
THERJR_RS12385	COG1596	polysaccharide export
THERJR_RS12390	COG0531	amino acid
THERJR_RS12395	COG1376	ErfK ybiS ycfS ynhG family protein
THERJR_RS12405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THERJR_RS12460	COG1598	PFAM Uncharacterised protein family UPF0150
THERJR_RS12490	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THERJR_RS12495	COG1518	maintenance of DNA repeat elements
THERJR_RS12540	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
THERJR_RS12565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THERJR_RS12595	COG0495	leucyl-tRNA aminoacylation
THERJR_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
THERJR_RS12610	COG0799	negative regulation of ribosome biogenesis
THERJR_RS12615	COG1713	HD superfamily hydrolase involved in NAD metabolism
THERJR_RS12620	COG0724	RNA recognition motif
THERJR_RS12625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THERJR_RS12635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
THERJR_RS12640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
THERJR_RS12645	COG1534	Rna-binding protein
THERJR_RS12655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THERJR_RS12675	COG0697	spore germination
THERJR_RS12680	COG0697	spore germination
THERJR_RS12685	COG0531	amino acid
THERJR_RS12695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THERJR_RS12725	COG1530	ribonuclease E activity
THERJR_RS12735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS12740	COG1994	Peptidase M50
THERJR_RS12750	COG0772	Belongs to the SEDS family
THERJR_RS12755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
THERJR_RS12760	COG2894	cell division
THERJR_RS12765	COG0850	regulation of cytokinetic process
THERJR_RS12770	COG0768	penicillin binding
THERJR_RS12785	COG1077	Cell shape determining protein MreB Mrl
THERJR_RS12790	COG2003	Belongs to the UPF0758 family
THERJR_RS12795	COG0424	maF-like protein
THERJR_RS12820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
THERJR_RS12830	COG0285	dihydrofolate synthase activity
THERJR_RS12840	COG0525	valine-tRNA ligase activity
THERJR_RS12850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
THERJR_RS12855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THERJR_RS12860	COG0470	DNA polymerase III
THERJR_RS12860	COG1067	ATP-dependent peptidase activity
THERJR_RS12865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THERJR_RS12870	COG0740	serine-type endopeptidase activity
THERJR_RS12875	COG0544	peptidyl-prolyl cis-trans isomerase activity
THERJR_RS12925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THERJR_RS12930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
THERJR_RS12935	COG1234	tRNA 3'-trailer cleavage
THERJR_RS12940	COG1924	4 iron, 4 sulfur cluster binding
THERJR_RS12950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
THERJR_RS13010	COG1191	sigma factor activity
THERJR_RS13015	COG4447	cellulose binding
THERJR_RS13025	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
THERJR_RS13035	COG3344	reverse transcriptase
THERJR_RS13055	COG3679	Belongs to the UPF0342 family
THERJR_RS13065	COG0613	PHP domain protein
THERJR_RS13120	COG1242	4 iron, 4 sulfur cluster binding
THERJR_RS13125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THERJR_RS13140	COG0390	transport system, permease component
THERJR_RS13145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THERJR_RS13155	COG0372	Belongs to the citrate synthase family
THERJR_RS13160	COG2207	Transcriptional regulator
THERJR_RS13165	COG2814	Major facilitator Superfamily
THERJR_RS13175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
THERJR_RS13180	COG2211	Major facilitator Superfamily
THERJR_RS13185	COG2211	Major facilitator Superfamily
THERJR_RS13195	COG5012	cobalamin binding
THERJR_RS13210	COG2188	Transcriptional regulator
THERJR_RS13215	COG5012	cobalamin binding
THERJR_RS13225	COG2271	Major facilitator Superfamily
THERJR_RS13235	COG5012	cobalamin binding
THERJR_RS13245	COG0840	transmembrane signaling receptor activity
THERJR_RS13255	COG0577	efflux transmembrane transporter activity
THERJR_RS13255	COG1136	(ABC) transporter
THERJR_RS13260	COG1136	(ABC) transporter
THERJR_RS13260	COG4591	ABC-type transport system involved in lipoprotein release permease component
THERJR_RS13265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THERJR_RS13275	COG1131	(ABC) transporter
THERJR_RS13285	COG0745	RESPONSE REGULATOR receiver
THERJR_RS13290	COG5002	protein histidine kinase activity
THERJR_RS13295	COG5002	protein histidine kinase activity
THERJR_RS13300	COG0745	RESPONSE REGULATOR receiver
THERJR_RS13325	COG1733	regulation of RNA biosynthetic process
THERJR_RS13335	COG0778	Nitroreductase
THERJR_RS13345	COG2391	methyltransferase activity
THERJR_RS13360	COG3290	protein histidine kinase activity
THERJR_RS13400	COG5001	Diguanylate cyclase
THERJR_RS13400	COG3300	MHYT domain
THERJR_RS13430	COG0411	ABC transporter
THERJR_RS13450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
THERJR_RS13455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
THERJR_RS13460	COG0438	transferase activity, transferring glycosyl groups
THERJR_RS13485	COG0789	Transcriptional regulator
THERJR_RS13505	COG0477	Major facilitator Superfamily
THERJR_RS13515	COG5002	protein histidine kinase activity
THERJR_RS13520	COG0745	RESPONSE REGULATOR receiver
THERJR_RS13530	COG3842	ATPase activity
THERJR_RS13535	COG4120	Belongs to the binding-protein-dependent transport system permease family
THERJR_RS13550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THERJR_RS13555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THERJR_RS13565	COG0557	exoribonuclease II activity
THERJR_RS13575	COG0318	PFAM AMP-dependent synthetase and ligase
THERJR_RS13580	COG0318	PFAM AMP-dependent synthetase and ligase
THERJR_RS13585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THERJR_RS13600	COG1131	(ABC) transporter
THERJR_RS13605	COG1725	Transcriptional regulator
THERJR_RS13615	COG1131	(ABC) transporter
THERJR_RS13620	COG1725	Transcriptional regulator
THERJR_RS13630	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THERJR_RS13635	COG0148	phosphopyruvate hydratase activity
THERJR_RS13640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
THERJR_RS13645	COG0149	triose-phosphate isomerase activity
THERJR_RS13650	COG0126	phosphoglycerate kinase activity
THERJR_RS13665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
THERJR_RS13675	COG1481	regulation of sporulation
THERJR_RS13685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
THERJR_RS13690	COG1660	Displays ATPase and GTPase activities
THERJR_RS13695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THERJR_RS13700	COG1940	carbohydrate kinase activity
THERJR_RS13705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
THERJR_RS13710	COG2222	sugar isomerase
THERJR_RS13730	COG0561	phosphatase activity
THERJR_RS13735	COG1950	PFAM Membrane protein of
THERJR_RS13740	COG2119	membrane
THERJR_RS13750	COG0322	excinuclease ABC activity
THERJR_RS13755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THERJR_RS13760	COG0556	nucleotide-excision repair
THERJR_RS13770	COG1573	uracil-dna glycosylase
THERJR_RS13785	COG0793	Belongs to the peptidase S41A family
THERJR_RS13785	COG3409	Peptidoglycan-binding domain 1 protein
THERJR_RS13790	COG4942	peptidase
THERJR_RS13795	COG2177	Part of the ABC transporter FtsEX involved in
THERJR_RS13800	COG2884	Cell division ATP-binding protein ftsE
THERJR_RS13855	COG1404	Belongs to the peptidase S8 family
THERJR_RS13880	COG1404	Belongs to the peptidase S8 family
THERJR_RS13885	COG3279	Response regulator of the LytR AlgR family
THERJR_RS13895	COG3290	protein histidine kinase activity
THERJR_RS13905	COG3958	Transketolase
THERJR_RS13910	COG3959	Transketolase, thiamine diphosphate binding domain
THERJR_RS13915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
THERJR_RS13920	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
THERJR_RS13935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
THERJR_RS13940	COG0653	protein targeting
THERJR_RS13955	COG2199	diguanylate cyclase activity
THERJR_RS13955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS13965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
THERJR_RS13970	COG1278	Cold shock
THERJR_RS13980	COG1516	flagellar protein fliS
THERJR_RS13985	COG2089	acid synthase
THERJR_RS13995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
THERJR_RS14000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THERJR_RS14005	COG1083	cytidylyl-transferase
THERJR_RS14010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THERJR_RS14015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THERJR_RS14040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
THERJR_RS14050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THERJR_RS14055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
THERJR_RS14060	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
THERJR_RS14070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THERJR_RS14075	COG1256	bacterial-type flagellum assembly
THERJR_RS14075	COG4786	Flagellar basal body rod
THERJR_RS14100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
THERJR_RS14135	COG2197	response regulator
THERJR_RS14180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THERJR_RS14185	COG2323	membrane
THERJR_RS14190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THERJR_RS14195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THERJR_RS14200	COG0728	peptidoglycan biosynthetic process
THERJR_RS14220	COG1316	TRANSCRIPTIONal
THERJR_RS14245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THERJR_RS14275	COG0546	phosphoglycolate phosphatase activity
THERJR_RS14275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
THERJR_RS14290	COG0438	transferase activity, transferring glycosyl groups
THERJR_RS14315	COG0438	transferase activity, transferring glycosyl groups
THERJR_RS14330	COG1368	sulfuric ester hydrolase activity
THERJR_RS14335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THERJR_RS14350	COG1137	ATPase activity
THERJR_RS14355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THERJR_RS14385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THERJR_RS14395	COG4733	cellulase activity
THERJR_RS14395	COG5297	Belongs to the glycosyl hydrolase family 6
THERJR_RS14425	COG1408	metallophosphoesterase
THERJR_RS14430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THERJR_RS14435	COG2373	Large extracellular alpha-helical protein
THERJR_RS14500	COG4786	Flagellar basal body rod
THERJR_RS14510	COG1609	Transcriptional regulator
THERJR_RS14515	COG2385	sporulation resulting in formation of a cellular spore
THERJR_RS14520	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THERJR_RS14525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THERJR_RS14530	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
THERJR_RS14535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THERJR_RS14540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THERJR_RS14545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THERJR_RS14550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THERJR_RS14555	COG0356	it plays a direct role in the translocation of protons across the membrane
THERJR_RS14570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THERJR_RS14575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THERJR_RS14580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THERJR_RS14585	COG0698	ribose 5-phosphate isomerase
THERJR_RS14595	COG1971	Probably functions as a manganese efflux pump
THERJR_RS14600	COG0009	L-threonylcarbamoyladenylate synthase
THERJR_RS14605	COG0475	glutathione-regulated potassium exporter activity
THERJR_RS14610	COG2890	protein-(glutamine-N5) methyltransferase activity
THERJR_RS14615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THERJR_RS14620	COG3872	metal-dependent enzyme
THERJR_RS14625	COG0254	rRNA binding
THERJR_RS14640	COG0739	heme binding
THERJR_RS14655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THERJR_RS14665	COG1494	fructose-1,6-bisphosphatase
THERJR_RS14670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THERJR_RS14690	COG2204	response regulator
THERJR_RS14700	COG0616	signal peptide processing
THERJR_RS14705	COG0504	CTP synthase activity
THERJR_RS14710	COG3343	RNA polymerase activity
THERJR_RS14715	COG0018	arginyl-trna synthetase
THERJR_RS14745	COG0436	Aminotransferase
THERJR_RS14750	COG1522	sequence-specific DNA binding
THERJR_RS14760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
THERJR_RS14775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
THERJR_RS14780	COG2959	enzyme of heme biosynthesis
THERJR_RS14790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
THERJR_RS14795	COG1151	hydroxylamine reductase activity
THERJR_RS14805	COG5012	cobalamin binding
THERJR_RS14810	COG5598	trimethylamine methyltransferase
THERJR_RS14815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
THERJR_RS14820	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
THERJR_RS14825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
THERJR_RS14835	COG5012	cobalamin binding
THERJR_RS14840	COG2207	Transcriptional regulator
THERJR_RS14840	COG1917	Cupin 2, conserved barrel domain protein
THERJR_RS14845	COG1028	Short-chain dehydrogenase reductase Sdr
THERJR_RS14880	COG0409	Hydrogenase expression formation protein
THERJR_RS14890	COG1151	hydroxylamine reductase activity
THERJR_RS14920	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THERJR_RS14925	COG0650	Formate hydrogenlyase subunit 4
THERJR_RS14930	COG0651	ATP synthesis coupled electron transport
THERJR_RS14940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THERJR_RS14945	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
THERJR_RS14950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THERJR_RS14955	COG0305	Participates in initiation and elongation during chromosome replication
THERJR_RS14960	COG0470	DNA polymerase III
THERJR_RS14960	COG1067	ATP-dependent peptidase activity
THERJR_RS14965	COG0359	binds to the 23S rRNA
THERJR_RS14980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THERJR_RS14990	COG0360	Binds together with S18 to 16S ribosomal RNA
THERJR_RS14995	COG0012	GTP binding
THERJR_RS15005	COG0668	transmembrane transport
THERJR_RS15015	COG1362	aminopeptidase activity
THERJR_RS15055	COG2204	response regulator
THERJR_RS15090	COG1606	tRNA processing
THERJR_RS15095	COG1691	(AIR) carboxylase
THERJR_RS15110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
THERJR_RS15115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THERJR_RS15120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THERJR_RS15135	COG1475	DNA binding
THERJR_RS15140	COG1192	Involved in chromosome partitioning
THERJR_RS15145	COG0357	Ribosomal RNA small subunit methyltransferase G
THERJR_RS15150	COG0445	tRNA wobble uridine modification
THERJR_RS15155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THERJR_RS15160	COG1847	R3H domain protein
THERJR_RS15165	COG0706	membrane insertase activity
THERJR_RS15170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
THERJR_RS15175	COG0594	ribonuclease P activity
THERJR_RS15190	COG0791	NLP P60 protein
THERJR_RS15190	COG1388	LysM domain
THERJR_RS15205	COG0840	transmembrane signaling receptor activity
THERJR_RS15215	COG0840	transmembrane signaling receptor activity
THERJR_RS15230	COG1309	transcriptional regulator
THERJR_RS15235	COG0739	heme binding
THERJR_RS15235	COG0741	lytic transglycosylase activity
THERJR_RS15235	COG1196	nuclear chromosome segregation
THERJR_RS15240	COG0326	Molecular chaperone. Has ATPase activity
THERJR_RS15250	COG2076	Multidrug Resistance protein
THERJR_RS15265	COG5002	protein histidine kinase activity
THERJR_RS15265	COG2198	Histidine kinase
THERJR_RS15265	COG0784	Response regulator, receiver
THERJR_RS15275	COG2197	response regulator
THERJR_RS15285	COG4869	propanediol catabolic process
THERJR_RS15295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS15305	COG1305	Transglutaminase-like
THERJR_RS15340	COG0732	type I restriction modification DNA specificity domain
THERJR_RS15345	COG1309	transcriptional regulator
THERJR_RS15360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS15360	COG2199	diguanylate cyclase activity
THERJR_RS15365	COG1361	Conserved repeat domain
THERJR_RS15375	COG1032	radical SAM domain protein
THERJR_RS15395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
THERJR_RS15395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
THERJR_RS15405	COG0791	NLP P60 protein
THERJR_RS15405	COG1388	LysM domain
THERJR_RS15405	COG3103	Sh3 type 3 domain protein
THERJR_RS15410	COG1525	nuclease
THERJR_RS15415	COG0850	regulation of cytokinetic process
THERJR_RS15420	COG3409	Peptidoglycan-binding domain 1 protein
THERJR_RS15420	COG3773	Cell wall hydrolase
THERJR_RS15425	COG1388	LysM domain
THERJR_RS15425	COG0791	NLP P60 protein
THERJR_RS15450	COG0840	transmembrane signaling receptor activity
THERJR_RS15470	COG1388	LysM domain
THERJR_RS15505	COG0456	acetyltransferase
THERJR_RS15520	COG2815	serine threonine protein kinase
THERJR_RS15520	COG0515	serine threonine protein kinase
THERJR_RS15530	COG0420	3'-5' exonuclease activity
THERJR_RS15545	COG1353	crispr-associated protein
THERJR_RS15550	COG3290	protein histidine kinase activity
THERJR_RS15550	COG3829	transcription factor binding
THERJR_RS15555	COG3706	GGDEF domain
THERJR_RS15565	COG0784	Response regulator, receiver
THERJR_RS15565	COG3437	response regulator, receiver
THERJR_RS15575	COG3409	Peptidoglycan-binding domain 1 protein
THERJR_RS15575	COG3773	Cell wall hydrolase
THERJR_RS15620	COG2205	protein histidine kinase activity
THERJR_RS15635	COG2199	diguanylate cyclase activity
THERJR_RS15635	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS15645	COG2247	cell wall binding repeat
THERJR_RS15645	COG0860	N-Acetylmuramoyl-L-alanine amidase
THERJR_RS15665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THERJR_RS15665	COG2199	diguanylate cyclase activity
THERJR_RS15670	COG1334	flagellar protein FlaG
THERJR_RS15675	COG5001	Diguanylate cyclase
THERJR_RS15705	COG3852	Histidine kinase