locus-tag	class	description
EB239_RS00035	COG3620	sequence-specific DNA binding
EB239_RS00070	COG1396	sequence-specific DNA binding
EB239_RS00080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EB239_RS00170	COG0739	heme binding
EB239_RS00250	COG2199	diguanylate cyclase activity
EB239_RS00250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EB239_RS00295	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EB239_RS00300	COG2894	cell division
EB239_RS00355	COG3620	sequence-specific DNA binding
EB239_RS00390	COG1396	sequence-specific DNA binding
EB239_RS00400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EB239_RS00420	COG0248	Ppx GppA phosphatase
EB239_RS00420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB239_RS00425	COG1098	S1 RNA binding domain
EB239_RS00460	COG2385	sporulation resulting in formation of a cellular spore
EB239_RS00470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EB239_RS00475	COG3344	reverse transcriptase
EB239_RS00485	COG0776	regulation of translation
EB239_RS00490	COG3956	TIGRFAM MazG family protein
EB239_RS00500	COG2814	Major facilitator Superfamily
EB239_RS00505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EB239_RS00510	COG5002	protein histidine kinase activity
EB239_RS00515	COG0745	RESPONSE REGULATOR receiver
EB239_RS00520	COG2033	superoxide reductase activity
EB239_RS00530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EB239_RS00560	COG0037	tRNA processing
EB239_RS00565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EB239_RS00610	COG0142	geranyltranstransferase activity
EB239_RS00625	COG1252	NADH dehydrogenase
EB239_RS00630	COG1528	Iron-storage protein
EB239_RS00645	COG0454	-acetyltransferase
EB239_RS00670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EB239_RS00720	COG1725	Transcriptional regulator
EB239_RS00725	COG1164	Oligoendopeptidase f
EB239_RS00745	COG0505	Belongs to the CarA family
EB239_RS00750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB239_RS00755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EB239_RS00760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EB239_RS00765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EB239_RS00780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EB239_RS00780	COG0493	'glutamate synthase
EB239_RS00785	COG1796	DNA polymerase
EB239_RS00785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EB239_RS00795	COG1131	(ABC) transporter
EB239_RS00815	COG1595	DNA-templated transcription, initiation
EB239_RS00830	COG1598	PFAM Uncharacterised protein family UPF0150
EB239_RS00850	COG0671	phosphoesterase, PA-phosphatase related
EB239_RS00855	COG3859	Proton-coupled thiamine transporter YuaJ
EB239_RS00860	COG1132	(ABC) transporter
EB239_RS00870	COG1846	Transcriptional regulator
EB239_RS00875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EB239_RS00875	COG1796	DNA polymerase
EB239_RS00890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB239_RS00905	COG0667	Aldo Keto reductase
EB239_RS00910	COG1725	Transcriptional regulator
EB239_RS00915	COG1131	(ABC) transporter
EB239_RS00930	COG0747	negative chemotaxis
EB239_RS00935	COG0601	transmembrane transport
EB239_RS00940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB239_RS00945	COG0444	Belongs to the ABC transporter superfamily
EB239_RS00950	COG4608	Belongs to the ABC transporter superfamily
EB239_RS00975	COG1131	(ABC) transporter
EB239_RS00995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EB239_RS01000	COG0018	arginyl-trna synthetase
EB239_RS01020	COG2959	enzyme of heme biosynthesis
EB239_RS01040	COG0531	amino acid
EB239_RS01045	COG0697	spore germination
EB239_RS01060	COG1802	Transcriptional regulator
EB239_RS01065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EB239_RS01075	COG4466	Protein conserved in bacteria
EB239_RS01085	COG2002	toxin-antitoxin pair type II binding
EB239_RS01090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EB239_RS01095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EB239_RS01110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB239_RS01115	COG5002	protein histidine kinase activity
EB239_RS01115	COG3850	Histidine kinase
EB239_RS01125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EB239_RS01130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB239_RS01135	COG2088	sporulation resulting in formation of a cellular spore
EB239_RS01140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB239_RS01145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB239_RS01155	COG1609	Transcriptional regulator
EB239_RS01170	COG0071	Belongs to the small heat shock protein (HSP20) family
EB239_RS01175	COG5611	PilT protein domain protein
EB239_RS01190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB239_RS01190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB239_RS01190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS01200	COG1349	DNA-binding transcription factor activity
EB239_RS01205	COG2373	Large extracellular alpha-helical protein
EB239_RS01215	COG2911	Protein conserved in bacteria
EB239_RS01215	COG1361	Conserved repeat domain
EB239_RS01215	COG3266	domain, Protein
EB239_RS01220	COG4991	sh3 domain protein
EB239_RS01220	COG3064	Membrane
EB239_RS01220	COG0515	serine threonine protein kinase
EB239_RS01235	COG0504	CTP synthase activity
EB239_RS01260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB239_RS01265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EB239_RS01285	COG0083	homoserine kinase activity
EB239_RS01290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EB239_RS01295	COG0460	homoserine dehydrogenase
EB239_RS01310	COG0531	amino acid
EB239_RS01315	COG3344	reverse transcriptase
EB239_RS01325	COG3344	reverse transcriptase
EB239_RS01335	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EB239_RS01345	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EB239_RS01350	COG1518	maintenance of DNA repeat elements
EB239_RS01405	COG0822	iron-sulfur transferase activity
EB239_RS01410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB239_RS01420	COG0719	Fe-S assembly protein
EB239_RS01425	COG0396	ATPase activity
EB239_RS01440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB239_RS01470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EB239_RS01480	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EB239_RS01490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB239_RS01495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB239_RS01515	COG5002	protein histidine kinase activity
EB239_RS01530	COG0739	heme binding
EB239_RS01540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EB239_RS01545	COG0308	aminopeptidase N
EB239_RS01560	COG0658	competence protein
EB239_RS01560	COG2333	competence protein COMEC
EB239_RS01570	COG0672	)-iron permease
EB239_RS01605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EB239_RS01610	COG0840	transmembrane signaling receptor activity
EB239_RS01620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB239_RS01625	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB239_RS01635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB239_RS01640	COG1164	Oligoendopeptidase f
EB239_RS01645	COG2226	methyltransferase
EB239_RS01655	COG1132	(ABC) transporter
EB239_RS01665	COG1132	(ABC) transporter
EB239_RS01680	COG1132	(ABC) transporter
EB239_RS01710	COG1131	(ABC) transporter
EB239_RS01740	COG1132	(ABC) transporter
EB239_RS01745	COG1132	(ABC) transporter
EB239_RS01765	COG0641	radical SAM
EB239_RS01780	COG0535	radical SAM domain protein
EB239_RS01790	COG4555	ABC transporter
EB239_RS01795	COG1032	radical SAM domain protein
EB239_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB239_RS01840	COG0305	Participates in initiation and elongation during chromosome replication
EB239_RS01850	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EB239_RS01865	COG3344	reverse transcriptase
EB239_RS01880	COG0629	single-stranded DNA binding
EB239_RS01890	COG4481	Protein conserved in bacteria
EB239_RS01895	COG0668	transmembrane transport
EB239_RS01905	COG3344	reverse transcriptase
EB239_RS01920	COG4242	Belongs to the peptidase S51 family
EB239_RS01925	COG1597	lipid kinase activity
EB239_RS01935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB239_RS01940	COG1475	DNA binding
EB239_RS01945	COG1192	Involved in chromosome partitioning
EB239_RS01970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EB239_RS01975	COG1847	R3H domain protein
EB239_RS01980	COG0706	membrane insertase activity
EB239_RS02005	COG0592	DNA-directed DNA polymerase activity
EB239_RS02010	COG2501	S4 domain
EB239_RS02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB239_RS02045	COG0187	DNA topoisomerase II activity
EB239_RS02050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB239_RS02055	COG1902	pentaerythritol trinitrate reductase activity
EB239_RS02060	COG0440	acetolactate synthase activity
EB239_RS02065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EB239_RS02070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB239_RS02075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EB239_RS02080	COG0066	3-isopropylmalate dehydratase activity
EB239_RS02085	COG0473	3-isopropylmalate dehydrogenase activity
EB239_RS02090	COG0129	dihydroxy-acid dehydratase activity
EB239_RS02095	COG0028	Belongs to the TPP enzyme family
EB239_RS02115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EB239_RS02120	COG0628	permease
EB239_RS02145	COG1316	TRANSCRIPTIONal
EB239_RS02155	COG1615	UPF0182 protein
EB239_RS02175	COG1863	multisubunit Na H antiporter MnhE subunit
EB239_RS02205	COG0651	ATP synthesis coupled electron transport
EB239_RS02210	COG0651	ATP synthesis coupled electron transport
EB239_RS02215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB239_RS02220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB239_RS02225	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB239_RS02225	COG0649	NAD binding
EB239_RS02230	COG0649	NAD binding
EB239_RS02265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EB239_RS02265	COG2199	diguanylate cyclase activity
EB239_RS02270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EB239_RS02280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EB239_RS02285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB239_RS02290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB239_RS02340	COG1028	Short-chain dehydrogenase reductase Sdr
EB239_RS02345	COG1187	pseudouridine synthase activity
EB239_RS02350	COG1609	Transcriptional regulator
EB239_RS02355	COG1653	transport
EB239_RS02360	COG1175	transmembrane transport
EB239_RS02365	COG0395	ABC-type sugar transport system, permease component
EB239_RS02380	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EB239_RS02385	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EB239_RS02390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB239_RS02405	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB239_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
EB239_RS02425	COG1511	domain protein
EB239_RS02435	COG0037	tRNA processing
EB239_RS02440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EB239_RS02440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EB239_RS02450	COG1573	uracil-dna glycosylase
EB239_RS02480	COG0425	Belongs to the sulfur carrier protein TusA family
EB239_RS02485	COG2391	methyltransferase activity
EB239_RS02505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB239_RS02510	COG0509	glycine decarboxylation via glycine cleavage system
EB239_RS02555	COG3344	reverse transcriptase
EB239_RS02565	COG0519	Catalyzes the synthesis of GMP from XMP
EB239_RS02590	COG1982	Orn Lys Arg decarboxylase major
EB239_RS02600	COG3870	Protein conserved in bacteria
EB239_RS02610	COG0470	DNA polymerase III
EB239_RS02615	COG1774	PSP1 C-terminal conserved region
EB239_RS02625	COG0730	response to heat
EB239_RS02635	COG2235	arginine
EB239_RS02645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EB239_RS02650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EB239_RS02655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB239_RS02660	COG2002	toxin-antitoxin pair type II binding
EB239_RS02665	COG2715	membrane protein required for spore maturation
EB239_RS02670	COG0700	Nucleoside recognition
EB239_RS02675	COG0617	tRNA 3'-terminal CCA addition
EB239_RS02685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB239_RS02685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB239_RS02690	COG0084	hydrolase, TatD family'
EB239_RS02695	COG3584	3D domain protein
EB239_RS02695	COG3583	domain protein
EB239_RS02700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB239_RS02720	COG4447	cellulose binding
EB239_RS02725	COG1191	sigma factor activity
EB239_RS02730	COG2151	metal-sulfur cluster biosynthetic enzyme
EB239_RS02730	COG0489	protein tyrosine kinase activity
EB239_RS02745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB239_RS02750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EB239_RS02750	COG2111	Na H antiporter
EB239_RS02755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB239_RS02760	COG3260	NADH ubiquinone oxidoreductase 20
EB239_RS02775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB239_RS02780	COG0375	protein maturation
EB239_RS02790	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EB239_RS02795	COG0298	carbon dioxide binding
EB239_RS02800	COG0409	Hydrogenase expression formation protein
EB239_RS02810	COG0745	RESPONSE REGULATOR receiver
EB239_RS02825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EB239_RS02840	COG3872	metal-dependent enzyme
EB239_RS02845	COG2890	protein-(glutamine-N5) methyltransferase activity
EB239_RS02855	COG0428	transporter
EB239_RS02860	COG0009	L-threonylcarbamoyladenylate synthase
EB239_RS02865	COG0698	ribose 5-phosphate isomerase
EB239_RS02880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB239_RS02885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EB239_RS02900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB239_RS02915	COG0686	Belongs to the AlaDH PNT family
EB239_RS02935	COG1361	Conserved repeat domain
EB239_RS02940	COG2385	sporulation resulting in formation of a cellular spore
EB239_RS02950	COG1609	Transcriptional regulator
EB239_RS02960	COG4786	Flagellar basal body rod
EB239_RS02975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EB239_RS03000	COG1496	oxidoreductase activity
EB239_RS03015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EB239_RS03015	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EB239_RS03030	COG3775	system Galactitol-specific IIC component
EB239_RS03060	COG4948	Mandelate Racemase Muconate Lactonizing
EB239_RS03065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB239_RS03070	COG0800	Aldolase
EB239_RS03080	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EB239_RS03080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EB239_RS03085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB239_RS03090	COG3715	PTS system
EB239_RS03095	COG3716	PTS system mannose fructose sorbose family IID component
EB239_RS03100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS03115	COG2222	sugar isomerase
EB239_RS03120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EB239_RS03125	COG0569	domain protein
EB239_RS03130	COG1082	Xylose isomerase domain protein TIM barrel
EB239_RS03135	COG2115	Belongs to the xylose isomerase family
EB239_RS03140	COG1070	Carbohydrate kinase
EB239_RS03145	COG1653	transport
EB239_RS03155	COG0395	ABC-type sugar transport system, permease component
EB239_RS03160	COG1472	Belongs to the glycosyl hydrolase 3 family
EB239_RS03180	COG1609	Transcriptional regulator
EB239_RS03185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB239_RS03195	COG1129	ABC transporter
EB239_RS03200	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB239_RS03205	COG1879	ABC-type sugar transport system periplasmic component
EB239_RS03210	COG1737	Transcriptional regulator
EB239_RS03215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EB239_RS03225	COG1175	transmembrane transport
EB239_RS03230	COG0395	ABC-type sugar transport system, permease component
EB239_RS03235	COG3842	ATPase activity
EB239_RS03245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EB239_RS03250	COG3876	Protein conserved in bacteria
EB239_RS03255	COG1472	Belongs to the glycosyl hydrolase 3 family
EB239_RS03260	COG2971	BadF BadG BcrA BcrD
EB239_RS03265	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EB239_RS03275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EB239_RS03280	COG0456	acetyltransferase
EB239_RS03285	COG1649	PFAM Uncharacterised BCR, COG1649
EB239_RS03295	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB239_RS03300	COG0277	FAD linked oxidase domain protein
EB239_RS03315	COG1297	OPT oligopeptide transporter protein
EB239_RS03325	COG0436	Aminotransferase
EB239_RS03330	COG1522	sequence-specific DNA binding
EB239_RS03340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EB239_RS03340	COG1918	ferrous iron import across plasma membrane
EB239_RS03355	COG1122	ATPase activity
EB239_RS03360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EB239_RS03365	COG0310	cobalt ion transport
EB239_RS03370	COG0310	cobalt ion transport
EB239_RS03375	COG0864	Transcriptional regulator
EB239_RS03395	COG0477	Major facilitator Superfamily
EB239_RS03405	COG1131	(ABC) transporter
EB239_RS03415	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EB239_RS03430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB239_RS03435	COG0534	Mate efflux family protein
EB239_RS03440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB239_RS03445	COG1136	(ABC) transporter
EB239_RS03450	COG1136	(ABC) transporter
EB239_RS03450	COG0577	efflux transmembrane transporter activity
EB239_RS03465	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB239_RS03485	COG1074	ATP-dependent DNA helicase activity
EB239_RS03490	COG0420	3'-5' exonuclease activity
EB239_RS03495	COG0419	ATPase involved in DNA repair
EB239_RS03505	COG0450	alkyl hydroperoxide reductase
EB239_RS03530	COG0297	glycogen (starch) synthase activity
EB239_RS03535	COG0586	Pfam SNARE associated Golgi protein
EB239_RS03590	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EB239_RS03595	COG1980	fructose-bisphosphate aldolase activity
EB239_RS03605	COG2972	Histidine kinase
EB239_RS03610	COG2197	response regulator
EB239_RS03615	COG4213	ABC transporter substrate-binding protein
EB239_RS03620	COG4213	ABC transporter substrate-binding protein
EB239_RS03625	COG1129	ABC transporter
EB239_RS03630	COG4214	carbohydrate transport
EB239_RS03635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB239_RS03640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EB239_RS03655	COG0095	Lipoate-protein ligase
EB239_RS03660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB239_RS03675	COG3344	reverse transcriptase
EB239_RS03680	COG0436	Aminotransferase
EB239_RS03685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS03695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EB239_RS03710	COG3959	Transketolase, thiamine diphosphate binding domain
EB239_RS03715	COG3958	Transketolase
EB239_RS03725	COG0205	6-phosphofructokinase activity
EB239_RS03760	COG3732	PTS system glucitol sorbitol-specific
EB239_RS03775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB239_RS03820	COG3711	transcriptional antiterminator
EB239_RS03820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS03825	COG1979	alcohol dehydrogenase
EB239_RS03865	COG0640	Transcriptional regulator
EB239_RS03905	COG1309	transcriptional regulator
EB239_RS03920	COG1924	4 iron, 4 sulfur cluster binding
EB239_RS03935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB239_RS03940	COG0390	transport system, permease component
EB239_RS03945	COG0823	Involved in the tonB-independent uptake of proteins
EB239_RS03955	COG0495	leucyl-tRNA aminoacylation
EB239_RS03960	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EB239_RS03970	COG1522	sequence-specific DNA binding
EB239_RS03970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB239_RS03975	COG2313	pseudouridylate synthase activity
EB239_RS03985	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EB239_RS03985	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EB239_RS04005	COG1447	Phosphotransferase system cellobiose-specific component IIA
EB239_RS04010	COG1486	melibiose metabolic process
EB239_RS04015	COG2723	6-phospho-beta-galactosidase activity
EB239_RS04020	COG2213	PTS system mannitol-specific
EB239_RS04025	COG3711	transcriptional antiterminator
EB239_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS04035	COG0246	Mannitol dehydrogenase
EB239_RS04045	COG0737	Belongs to the 5'-nucleotidase family
EB239_RS04055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB239_RS04060	COG0730	response to heat
EB239_RS04080	COG4166	transmembrane transport
EB239_RS04085	COG0601	transmembrane transport
EB239_RS04090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB239_RS04095	COG0444	Belongs to the ABC transporter superfamily
EB239_RS04105	COG3250	beta-galactosidase activity
EB239_RS04110	COG2723	6-phospho-beta-galactosidase activity
EB239_RS04115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB239_RS04120	COG1121	(ABC) transporter
EB239_RS04125	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB239_RS04130	COG0735	belongs to the Fur family
EB239_RS04135	COG0714	Associated with various cellular activities
EB239_RS04150	COG1704	LemA family
EB239_RS04155	COG0583	DNA-binding transcription factor activity
EB239_RS04180	COG0084	hydrolase, TatD family'
EB239_RS04190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB239_RS04195	COG0822	iron-sulfur transferase activity
EB239_RS04240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB239_RS04245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB239_RS04250	COG1120	ATPase activity
EB239_RS04255	COG1797	cobyrinic acid a,c-diamide synthase activity
EB239_RS04280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB239_RS04290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EB239_RS04320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EB239_RS04335	COG0113	porphobilinogen synthase activity
EB239_RS04340	COG1648	precorrin-2 dehydrogenase activity
EB239_RS04340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EB239_RS04355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB239_RS04375	COG0456	acetyltransferase
EB239_RS04375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EB239_RS04390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EB239_RS04395	COG1121	(ABC) transporter
EB239_RS04475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB239_RS04510	COG1131	(ABC) transporter
EB239_RS04555	COG1105	Belongs to the carbohydrate kinase PfkB family
EB239_RS04590	COG1131	(ABC) transporter
EB239_RS04605	COG0778	Nitroreductase
EB239_RS04630	COG4555	ABC transporter
EB239_RS04635	COG1668	transmembrane transport
EB239_RS04725	COG1131	(ABC) transporter
EB239_RS04825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EB239_RS04825	COG2199	diguanylate cyclase activity
EB239_RS04830	COG0840	transmembrane signaling receptor activity
EB239_RS04835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EB239_RS04845	COG1228	amidohydrolase
EB239_RS04860	COG1744	ABC transporter substrate-binding protein PnrA-like
EB239_RS04865	COG3845	ABC transporter
EB239_RS04870	COG4603	Belongs to the binding-protein-dependent transport system permease family
EB239_RS04875	COG1079	Belongs to the binding-protein-dependent transport system permease family
EB239_RS04880	COG2188	Transcriptional regulator
EB239_RS04900	COG0840	transmembrane signaling receptor activity
EB239_RS04915	COG1263	PTS System
EB239_RS04915	COG2190	(PTS) system
EB239_RS04915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB239_RS04920	COG2190	(PTS) system
EB239_RS04925	COG3711	transcriptional antiterminator
EB239_RS04930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB239_RS04960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EB239_RS04970	COG2323	membrane
EB239_RS04975	COG0561	phosphatase activity
EB239_RS04980	COG1609	Transcriptional regulator
EB239_RS04985	COG0745	RESPONSE REGULATOR receiver
EB239_RS04990	COG5002	protein histidine kinase activity
EB239_RS05035	COG1592	Rubrerythrin
EB239_RS05040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB239_RS05045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB239_RS05050	COG1040	competence protein
EB239_RS05070	COG4786	Flagellar basal body rod
EB239_RS05070	COG1256	bacterial-type flagellum assembly
EB239_RS05075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EB239_RS05085	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EB239_RS05090	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EB239_RS05105	COG0367	asparagine synthase
EB239_RS05130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EB239_RS05135	COG1516	flagellar protein fliS
EB239_RS05145	COG0840	transmembrane signaling receptor activity
EB239_RS05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB239_RS05165	COG0765	amino acid transport
EB239_RS05195	COG1827	regulation of RNA biosynthetic process
EB239_RS05205	COG0653	protein targeting
EB239_RS05210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EB239_RS05215	COG2183	response to ionizing radiation
EB239_RS05230	COG0398	Pfam SNARE associated Golgi protein
EB239_RS05240	COG2235	arginine
EB239_RS05245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB239_RS05250	COG0549	Belongs to the carbamate kinase family
EB239_RS05260	COG0802	atpase or kinase
EB239_RS05265	COG1214	PFAM Peptidase M22, glycoprotease
EB239_RS05275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EB239_RS05285	COG0488	(ABC) transporter
EB239_RS05290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EB239_RS05305	COG1024	Enoyl-CoA hydratase
EB239_RS05310	COG1960	acyl-CoA dehydrogenase activity
EB239_RS05315	COG2086	electron transfer activity
EB239_RS05320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB239_RS05325	COG1250	3-hydroxyacyl-CoA dehydrogenase
EB239_RS05335	COG0183	Belongs to the thiolase family
EB239_RS05345	COG2030	dehydratase
EB239_RS05375	COG2267	carboxylic ester hydrolase activity
EB239_RS05380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB239_RS05385	COG0427	acetyl-CoA hydrolase
EB239_RS05405	COG0840	transmembrane signaling receptor activity
EB239_RS05410	COG3426	butyrate kinase activity
EB239_RS05420	COG3279	Response regulator of the LytR AlgR family
EB239_RS05425	COG3290	protein histidine kinase activity
EB239_RS05450	COG0493	'glutamate synthase
EB239_RS05455	COG0424	maF-like protein
EB239_RS05460	COG1811	Na channel or pump
EB239_RS05470	COG1404	Belongs to the peptidase S8 family
EB239_RS05485	COG3344	reverse transcriptase
EB239_RS05535	COG3344	reverse transcriptase
EB239_RS05540	COG0516	GMP reductase activity
EB239_RS05540	COG0517	IMP dehydrogenase activity
EB239_RS05545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB239_RS05545	COG0519	Catalyzes the synthesis of GMP from XMP
EB239_RS05550	COG2252	PERMEase
EB239_RS05555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EB239_RS05565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB239_RS05570	COG0047	phosphoribosylformylglycinamidine synthase activity
EB239_RS05575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB239_RS05580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB239_RS05585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EB239_RS05590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB239_RS05600	COG0151	Belongs to the GarS family
EB239_RS05610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB239_RS05615	COG1473	amidohydrolase
EB239_RS05625	COG2244	polysaccharide biosynthetic process
EB239_RS05635	COG3711	transcriptional antiterminator
EB239_RS05645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB239_RS05650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB239_RS05655	COG1447	Phosphotransferase system cellobiose-specific component IIA
EB239_RS05660	COG4496	protein, YerC YecD
EB239_RS05665	COG0210	DNA helicase
EB239_RS05685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB239_RS05710	COG0860	N-Acetylmuramoyl-L-alanine amidase
EB239_RS05710	COG2247	cell wall binding repeat
EB239_RS05800	COG0004	ammonium transporteR
EB239_RS05805	COG0347	Belongs to the P(II) protein family
EB239_RS05810	COG0505	Belongs to the CarA family
EB239_RS05815	COG0067	glutamate synthase
EB239_RS05825	COG0437	4 iron, 4 sulfur cluster binding
EB239_RS05840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EB239_RS05850	COG0351	phosphomethylpyrimidine kinase
EB239_RS05855	COG0352	thiamine-phosphate diphosphorylase activity
EB239_RS05860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EB239_RS05895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EB239_RS05900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EB239_RS05915	COG0356	it plays a direct role in the translocation of protons across the membrane
EB239_RS05920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB239_RS05925	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB239_RS05930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB239_RS05935	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EB239_RS05940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EB239_RS05945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EB239_RS05950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EB239_RS05960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EB239_RS05960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EB239_RS05965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB239_RS05970	COG1116	anion transmembrane transporter activity
EB239_RS06040	COG0463	Glycosyl transferase, family 2
EB239_RS06055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EB239_RS06060	COG1091	dTDP-4-dehydrorhamnose reductase activity
EB239_RS06085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB239_RS06100	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB239_RS06185	COG1704	LemA family
EB239_RS06190	COG0622	Phosphoesterase
EB239_RS06195	COG4989	oxidoreductase activity
EB239_RS06205	COG1914	H( )-stimulated, divalent metal cation uptake system
EB239_RS06225	COG1598	PFAM Uncharacterised protein family UPF0150
EB239_RS06270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EB239_RS06275	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EB239_RS06280	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EB239_RS06300	COG3344	reverse transcriptase
EB239_RS06305	COG1607	acyl-coa hydrolase
EB239_RS06310	COG3246	L-lysine catabolic process to acetate
EB239_RS06315	COG0604	alcohol dehydrogenase
EB239_RS06330	COG1193	negative regulation of DNA recombination
EB239_RS06335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EB239_RS06340	COG5012	cobalamin binding
EB239_RS06350	COG0250	Participates in transcription elongation, termination and antitermination
EB239_RS06360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EB239_RS06370	COG3949	Membrane
EB239_RS06380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB239_RS06395	COG2814	Major facilitator Superfamily
EB239_RS06435	COG0671	phosphoesterase, PA-phosphatase related
EB239_RS06460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB239_RS06465	COG0840	transmembrane signaling receptor activity
EB239_RS06470	COG1606	tRNA processing
EB239_RS06475	COG1691	(AIR) carboxylase
EB239_RS06480	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EB239_RS06485	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EB239_RS06490	COG5002	protein histidine kinase activity
EB239_RS06495	COG0745	RESPONSE REGULATOR receiver
EB239_RS06535	COG2197	response regulator
EB239_RS06605	COG0525	valine-tRNA ligase activity
EB239_RS06615	COG0285	dihydrofolate synthase activity
EB239_RS06650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EB239_RS06655	COG1609	Transcriptional regulator
EB239_RS06665	COG1653	transport
EB239_RS06670	COG1175	transmembrane transport
EB239_RS06675	COG0395	ABC-type sugar transport system, permease component
EB239_RS06680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB239_RS06695	COG0395	ABC-type sugar transport system, permease component
EB239_RS06710	COG1404	Belongs to the peptidase S8 family
EB239_RS06715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EB239_RS06715	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EB239_RS06720	COG3409	Peptidoglycan-binding domain 1 protein
EB239_RS06720	COG3773	Cell wall hydrolase
EB239_RS06735	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EB239_RS06745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB239_RS06755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EB239_RS06765	COG1132	(ABC) transporter
EB239_RS06770	COG1132	(ABC) transporter
EB239_RS06790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EB239_RS06795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB239_RS06805	COG0739	heme binding
EB239_RS06825	COG2986	histidine ammonia-lyase
EB239_RS06840	COG1131	(ABC) transporter
EB239_RS06850	COG0616	signal peptide processing
EB239_RS06890	COG4475	Protein of unknown function (DUF436)
EB239_RS06915	COG1983	PspC domain protein
EB239_RS06925	COG0726	polysaccharide deacetylase
EB239_RS06935	COG1113	amino acid transport
EB239_RS06955	COG1966	Carbon starvation protein
EB239_RS06960	COG3279	Response regulator of the LytR AlgR family
EB239_RS06965	COG3275	phosphorelay sensor kinase activity
EB239_RS06970	COG1595	DNA-templated transcription, initiation
EB239_RS06980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB239_RS06980	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB239_RS06985	COG0237	dephospho-CoA kinase activity
EB239_RS06990	COG0741	lytic transglycosylase activity
EB239_RS07015	COG0791	NLP P60 protein
EB239_RS07020	COG1217	gtp-binding protein TYPA
EB239_RS07030	COG3344	reverse transcriptase
EB239_RS07035	COG0741	lytic transglycosylase activity
EB239_RS07055	COG2878	Part of a membrane complex involved in electron transport
EB239_RS07080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB239_RS07080	COG4191	Histidine kinase
EB239_RS07110	COG2003	Belongs to the UPF0758 family
EB239_RS07115	COG1077	Cell shape determining protein MreB Mrl
EB239_RS07140	COG2894	cell division
EB239_RS07150	COG0772	Belongs to the SEDS family
EB239_RS07160	COG0739	heme binding
EB239_RS07165	COG1994	Peptidase M50
EB239_RS07165	COG0517	IMP dehydrogenase activity
EB239_RS07180	COG1530	ribonuclease E activity
EB239_RS07200	COG4708	membrane
EB239_RS07280	COG1713	HD superfamily hydrolase involved in NAD metabolism
EB239_RS07285	COG1316	TRANSCRIPTIONal
EB239_RS07290	COG0799	negative regulation of ribosome biogenesis
EB239_RS07310	COG0367	asparagine synthase
EB239_RS07315	COG1686	Belongs to the peptidase S11 family
EB239_RS07320	COG1596	polysaccharide export
EB239_RS07320	COG1555	photosystem II stabilization
EB239_RS07330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EB239_RS07360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB239_RS07365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB239_RS07380	COG4720	Psort location CytoplasmicMembrane, score
EB239_RS07390	COG1234	tRNA 3'-trailer cleavage
EB239_RS07395	COG2333	competence protein COMEC
EB239_RS07395	COG0658	competence protein
EB239_RS07405	COG0268	Binds directly to 16S ribosomal RNA
EB239_RS07415	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EB239_RS07445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB239_RS07450	COG1420	regulation of RNA biosynthetic process
EB239_RS07455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EB239_RS07460	COG0443	Heat shock 70 kDa protein
EB239_RS07465	COG0484	heat shock protein binding
EB239_RS07470	COG2264	protein methyltransferase activity
EB239_RS07475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EB239_RS07485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB239_RS07490	COG0537	adenosine 5'-monophosphoramidase activity
EB239_RS07520	COG1702	phosphate starvation-inducible protein PhoH
EB239_RS07525	COG1480	7TM receptor with intracellular HD hydrolase
EB239_RS07535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EB239_RS07560	COG0423	glycine-tRNA ligase activity
EB239_RS07565	COG0517	IMP dehydrogenase activity
EB239_RS07575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB239_RS07575	COG0574	Belongs to the PEP-utilizing enzyme family
EB239_RS07605	COG0557	exoribonuclease II activity
EB239_RS07650	COG0693	protein deglycase activity
EB239_RS07655	COG0583	DNA-binding transcription factor activity
EB239_RS07665	COG2267	carboxylic ester hydrolase activity
EB239_RS07695	COG0584	glycerophosphoryl diester phosphodiesterase
EB239_RS07705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EB239_RS07745	COG0426	domain, Protein
EB239_RS07750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB239_RS07760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EB239_RS07765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EB239_RS07770	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EB239_RS07785	COG1760	l-serine dehydratase
EB239_RS07790	COG1164	Oligoendopeptidase f
EB239_RS07795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EB239_RS07800	COG1605	Chorismate mutase
EB239_RS07800	COG0077	Prephenate dehydratase
EB239_RS07805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EB239_RS07810	COG0287	Prephenate dehydrogenase
EB239_RS07820	COG0745	RESPONSE REGULATOR receiver
EB239_RS07825	COG3850	Histidine kinase
EB239_RS07825	COG5002	protein histidine kinase activity
EB239_RS07835	COG2119	membrane
EB239_RS07855	COG0745	RESPONSE REGULATOR receiver
EB239_RS07860	COG2205	protein histidine kinase activity
EB239_RS07890	COG0363	glucosamine-6-phosphate deaminase activity
EB239_RS07900	COG3344	reverse transcriptase
EB239_RS07930	COG1136	(ABC) transporter
EB239_RS07940	COG0785	Cytochrome C biogenesis protein
EB239_RS07945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB239_RS07950	COG3118	belongs to the thioredoxin family
EB239_RS07955	COG1982	Orn Lys Arg decarboxylase major
EB239_RS08075	COG1215	transferase activity, transferring glycosyl groups
EB239_RS08080	COG3706	GGDEF domain
EB239_RS08105	COG0531	amino acid
EB239_RS08115	COG0653	protein targeting
EB239_RS08125	COG1131	(ABC) transporter
EB239_RS08135	COG2814	Major facilitator Superfamily
EB239_RS08155	COG3829	transcription factor binding
EB239_RS08160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EB239_RS08190	COG2972	Histidine kinase
EB239_RS08195	COG2197	response regulator
EB239_RS08200	COG1971	Probably functions as a manganese efflux pump
EB239_RS08210	COG3344	reverse transcriptase
EB239_RS08255	COG4869	propanediol catabolic process
EB239_RS08270	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EB239_RS08280	COG1012	belongs to the aldehyde dehydrogenase family
EB239_RS08285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB239_RS08290	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EB239_RS08295	COG4810	utilization protein
EB239_RS08320	COG1454	alcohol dehydrogenase
EB239_RS08335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB239_RS08340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB239_RS08345	COG1120	ATPase activity
EB239_RS08350	COG1797	cobyrinic acid a,c-diamide synthase activity
EB239_RS08420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB239_RS08435	COG1739	Uncharacterized protein family UPF0029
EB239_RS08455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EB239_RS08465	COG0835	chemotaxis
EB239_RS08475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EB239_RS08495	COG2247	cell wall binding repeat
EB239_RS08495	COG2385	sporulation resulting in formation of a cellular spore
EB239_RS08505	COG0343	queuine tRNA-ribosyltransferase activity
EB239_RS08525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EB239_RS08530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EB239_RS08535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EB239_RS08540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EB239_RS08550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EB239_RS08550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EB239_RS08555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB239_RS08560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EB239_RS08570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB239_RS08575	COG0577	efflux transmembrane transporter activity
EB239_RS08580	COG1136	(ABC) transporter
EB239_RS08585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB239_RS08590	COG1846	Transcriptional regulator
EB239_RS08600	COG0124	histidyl-tRNA synthetase
EB239_RS08605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EB239_RS08615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EB239_RS08620	COG1937	Protein conserved in bacteria
EB239_RS08625	COG3118	belongs to the thioredoxin family
EB239_RS08630	COG3804	dihydrodipicolinate reductase
EB239_RS08640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EB239_RS08650	COG5012	cobalamin binding
EB239_RS08660	COG3457	Alanine racemase
EB239_RS08670	COG1959	2 iron, 2 sulfur cluster binding
EB239_RS08680	COG0628	permease
EB239_RS08695	COG4472	Bacterial protein of unknown function (DUF965)
EB239_RS08705	COG3906	Belongs to the UPF0473 family
EB239_RS08710	COG0735	belongs to the Fur family
EB239_RS08715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EB239_RS08720	COG3679	Belongs to the UPF0342 family
EB239_RS08725	COG4708	membrane
EB239_RS08730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EB239_RS08735	COG4122	O-methyltransferase activity
EB239_RS08740	COG0826	peptidase U32
EB239_RS08745	COG0768	penicillin binding
EB239_RS08755	COG0546	phosphoglycolate phosphatase activity
EB239_RS08760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB239_RS08765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EB239_RS08775	COG1459	type II secretion system
EB239_RS08785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EB239_RS08830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EB239_RS08845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EB239_RS08855	COG0006	proline dipeptidase activity
EB239_RS08870	COG3854	ATPases associated with a variety of cellular activities
EB239_RS08910	COG1302	Protein conserved in bacteria
EB239_RS08920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB239_RS08925	COG1570	exodeoxyribonuclease VII activity
EB239_RS08930	COG1722	exodeoxyribonuclease VII activity
EB239_RS08945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EB239_RS08950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EB239_RS08965	COG1438	arginine binding
EB239_RS08970	COG0497	DNA recombination
EB239_RS08975	COG0750	zinc metalloprotease
EB239_RS09015	COG1379	DNA repair
EB239_RS09020	COG1300	Membrane
EB239_RS09025	COG4974	Belongs to the 'phage' integrase family
EB239_RS09030	COG1686	Belongs to the peptidase S11 family
EB239_RS09040	COG3344	reverse transcriptase
EB239_RS09045	COG1366	Belongs to the anti-sigma-factor antagonist family
EB239_RS09060	COG3360	Dodecin
EB239_RS09080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EB239_RS09080	COG0617	tRNA 3'-terminal CCA addition
EB239_RS09080	COG0517	IMP dehydrogenase activity
EB239_RS09085	COG1994	Peptidase M50
EB239_RS09095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB239_RS09105	COG3874	Sporulation protein YtfJ
EB239_RS09110	COG1686	Belongs to the peptidase S11 family
EB239_RS09120	COG0445	tRNA wobble uridine modification
EB239_RS09125	COG1187	pseudouridine synthase activity
EB239_RS09145	COG0010	Belongs to the arginase family
EB239_RS09155	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB239_RS09155	COG1388	LysM domain
EB239_RS09175	COG0674	pyruvate-flavodoxin oxidoreductase activity
EB239_RS09175	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EB239_RS09180	COG1013	pyruvate-flavodoxin oxidoreductase activity
EB239_RS09205	COG0406	alpha-ribazole phosphatase activity
EB239_RS09225	COG2081	HI0933 family
EB239_RS09240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB239_RS09255	COG0539	negative regulation of cytoplasmic translation
EB239_RS09255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EB239_RS09265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EB239_RS09270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB239_RS09275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EB239_RS09295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EB239_RS09305	COG4974	Belongs to the 'phage' integrase family
EB239_RS09310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EB239_RS09315	COG0464	growth
EB239_RS09320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB239_RS09330	COG0613	PHP domain protein
EB239_RS09335	COG2359	stage V sporulation protein S
EB239_RS09340	COG1692	metallophosphoesterase
EB239_RS09350	COG2137	regulation of response to DNA damage stimulus
EB239_RS09355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EB239_RS09360	COG1546	Belongs to the CinA family
EB239_RS09360	COG1058	Belongs to the CinA family
EB239_RS09365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB239_RS09370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB239_RS09375	COG1674	ftsk spoiiie
EB239_RS09385	COG0740	serine-type endopeptidase activity
EB239_RS09390	COG0527	aspartate kinase activity
EB239_RS09405	COG0612	Peptidase, M16
EB239_RS09410	COG0726	polysaccharide deacetylase
EB239_RS09415	COG1185	polyribonucleotide nucleotidyltransferase activity
EB239_RS09425	COG0196	riboflavin kinase activity
EB239_RS09430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EB239_RS09435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EB239_RS09440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EB239_RS09455	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EB239_RS09460	COG0195	Participates in both transcription termination and antitermination
EB239_RS09465	COG0779	Required for maturation of 30S ribosomal subunits
EB239_RS09470	COG2176	DNA-directed DNA polymerase activity
EB239_RS09480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EB239_RS09485	COG0750	zinc metalloprotease
EB239_RS09490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EB239_RS09495	COG4589	Belongs to the CDS family
EB239_RS09500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB239_RS09515	COG0528	UMP kinase activity
EB239_RS09540	COG1191	sigma factor activity
EB239_RS09545	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EB239_RS09550	COG1776	CheC inhibitor of MCP methylation
EB239_RS09555	COG0835	chemotaxis
EB239_RS09560	COG2198	Histidine kinase
EB239_RS09560	COG0643	Histidine kinase
EB239_RS09565	COG2201	protein-glutamate methylesterase activity
EB239_RS09575	COG0455	bacterial-type flagellum organization
EB239_RS09580	COG1419	protein localization to endoplasmic reticulum
EB239_RS09585	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB239_RS09590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EB239_RS09595	COG1684	flagellar biosynthetic protein fliR
EB239_RS09600	COG1987	bacterial-type flagellum assembly
EB239_RS09605	COG1338	Plays a role in the flagellum-specific transport system
EB239_RS09615	COG2201	protein-glutamate methylesterase activity
EB239_RS09620	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB239_RS09620	COG1776	CheC inhibitor of MCP methylation
EB239_RS09625	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB239_RS09635	COG1582	Flagellar protein (FlbD)
EB239_RS09650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EB239_RS09670	COG1157	protein secretion by the type III secretion system
EB239_RS09680	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EB239_RS09685	COG1766	The M ring may be actively involved in energy transduction
EB239_RS09690	COG1677	Flagellar hook-basal body complex protein FliE
EB239_RS09700	COG1815	bacterial-type flagellum-dependent cell motility
EB239_RS09705	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EB239_RS09710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EB239_RS09715	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EB239_RS09720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB239_RS09725	COG0758	DNA mediated transformation
EB239_RS09725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EB239_RS09730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EB239_RS09735	COG0792	nuclease activity
EB239_RS09740	COG0180	Tryptophanyl-tRNA synthetase
EB239_RS09745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB239_RS09750	COG0606	chelatase, subunit chli
EB239_RS09765	COG0336	Belongs to the RNA methyltransferase TrmD family
EB239_RS09775	COG1837	Belongs to the UPF0109 family
EB239_RS09780	COG0228	four-way junction DNA binding
EB239_RS09785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EB239_RS09790	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EB239_RS09795	COG0552	protein localization to endoplasmic reticulum
EB239_RS09810	COG2359	stage V sporulation protein S
EB239_RS09820	COG0571	ribonuclease III activity
EB239_RS09825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB239_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
EB239_RS09840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB239_RS09845	COG2070	2-Nitropropane dioxygenase
EB239_RS09850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EB239_RS09855	COG0416	fatty acid biosynthetic process
EB239_RS09865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EB239_RS09870	COG1399	metal-binding, possibly nucleic acid-binding protein
EB239_RS09875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EB239_RS09880	COG0280	phosphate acetyltransferase
EB239_RS09890	COG3314	Sporulation integral membrane protein YlbJ
EB239_RS09905	COG0742	ribosomal rna small subunit methyltransferase
EB239_RS09920	COG1307	EDD domain protein, DegV family
EB239_RS09925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EB239_RS09930	COG1461	Dihydroxyacetone kinase
EB239_RS09935	COG1302	Protein conserved in bacteria
EB239_RS09955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EB239_RS09960	COG1162	GTPase activity
EB239_RS09965	COG2815	serine threonine protein kinase
EB239_RS09965	COG0515	serine threonine protein kinase
EB239_RS09970	COG0631	protein serine/threonine phosphatase activity
EB239_RS09980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB239_RS09980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB239_RS09985	COG2738	Putative neutral zinc metallopeptidase
EB239_RS09995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB239_RS10000	COG0242	peptide deformylase activity
EB239_RS10005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EB239_RS10010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EB239_RS10020	COG0194	GDP metabolic process
EB239_RS10030	COG1561	YicC-like family, N-terminal region
EB239_RS10035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EB239_RS10045	COG2814	Major facilitator Superfamily
EB239_RS10085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EB239_RS10090	COG2011	ABC-type metal ion transport system permease component
EB239_RS10110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB239_RS10130	COG0037	tRNA processing
EB239_RS10155	COG0543	2 iron, 2 sulfur cluster binding
EB239_RS10170	COG0540	Belongs to the ATCase OTCase family
EB239_RS10185	COG0564	pseudouridine synthase activity
EB239_RS10190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EB239_RS10225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EB239_RS10260	COG1337	RAMP superfamily
EB239_RS10285	COG1970	mechanosensitive ion channel activity
EB239_RS10295	COG0778	Nitroreductase
EB239_RS10315	COG1983	PspC domain protein
EB239_RS10335	COG0626	cystathionine gamma-synthase activity
EB239_RS10340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EB239_RS10345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EB239_RS10365	COG0134	indole-3-glycerol-phosphate synthase activity
EB239_RS10375	COG0512	Glutamine amidotransferase of anthranilate synthase
EB239_RS10375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EB239_RS10395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EB239_RS10425	COG3599	regulation of cell shape
EB239_RS10430	COG2302	S4 RNA-binding domain
EB239_RS10445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EB239_RS10475	COG4948	Mandelate Racemase Muconate Lactonizing
EB239_RS10490	COG2610	gluconate transmembrane transporter activity
EB239_RS10495	COG1929	Belongs to the glycerate kinase type-1 family
EB239_RS10525	COG2814	Major facilitator Superfamily
EB239_RS10535	COG1131	(ABC) transporter
EB239_RS10545	COG0653	protein targeting
EB239_RS10555	COG0531	amino acid
EB239_RS10590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EB239_RS10600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB239_RS10605	COG1160	GTP binding
EB239_RS10645	COG0704	Plays a role in the regulation of phosphate uptake
EB239_RS10650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB239_RS10655	COG0581	inorganic phosphate transmembrane transporter activity
EB239_RS10660	COG0573	inorganic phosphate transmembrane transporter activity
EB239_RS10665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EB239_RS10670	COG5002	protein histidine kinase activity
EB239_RS10675	COG0745	RESPONSE REGULATOR receiver
EB239_RS10680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB239_RS10685	COG1873	PFAM PRC-barrel domain
EB239_RS10695	COG1191	sigma factor activity
EB239_RS10700	COG1191	sigma factor activity
EB239_RS10710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB239_RS10715	COG0849	cell division
EB239_RS10720	COG3856	small basic protein
EB239_RS10735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB239_RS10745	COG0772	Belongs to the SEDS family
EB239_RS10750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB239_RS10760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EB239_RS10765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EB239_RS10770	COG0768	penicillin binding
EB239_RS10805	COG0612	Peptidase, M16
EB239_RS10810	COG0612	Peptidase, M16
EB239_RS10835	COG0012	GTP binding
EB239_RS10855	COG0301	tRNA thio-modification
EB239_RS10880	COG3344	reverse transcriptase
EB239_RS10900	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB239_RS10930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB239_RS10935	COG0459	protein refolding
EB239_RS10945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EB239_RS10950	COG0321	lipoyl(octanoyl) transferase activity
EB239_RS10960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB239_RS10985	COG2340	Cysteine-rich secretory protein family
EB239_RS10990	COG1362	aminopeptidase activity
EB239_RS11000	COG2197	response regulator
EB239_RS11020	COG1683	Conserved Protein
EB239_RS11025	COG1193	negative regulation of DNA recombination
EB239_RS11030	COG0826	peptidase U32
EB239_RS11040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB239_RS11040	COG0072	phenylalanine-tRNA ligase activity
EB239_RS11045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EB239_RS11050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB239_RS11055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EB239_RS11060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EB239_RS11065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EB239_RS11075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EB239_RS11085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB239_RS11090	COG4399	Belongs to the UPF0754 family
EB239_RS11110	COG0745	RESPONSE REGULATOR receiver
EB239_RS11115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB239_RS11150	COG1278	Cold shock
EB239_RS11155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EB239_RS11170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EB239_RS11175	COG1956	GAF domain-containing protein
EB239_RS11190	COG3344	reverse transcriptase
EB239_RS11205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB239_RS11225	COG1482	cell wall glycoprotein biosynthetic process
EB239_RS11240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EB239_RS11245	COG2384	SAM-dependent methyltransferase
EB239_RS11260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB239_RS11265	COG0358	DNA primase activity
EB239_RS11270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EB239_RS11275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB239_RS11280	COG0148	phosphopyruvate hydratase activity
EB239_RS11285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EB239_RS11290	COG0149	triose-phosphate isomerase activity
EB239_RS11295	COG0126	phosphoglycerate kinase activity
EB239_RS11305	COG2390	Transcriptional regulator
EB239_RS11325	COG1254	Belongs to the acylphosphatase family
EB239_RS11330	COG0561	phosphatase activity
EB239_RS11340	COG2720	vancomycin resistance protein
EB239_RS11345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EB239_RS11350	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EB239_RS11355	COG1067	ATP-dependent peptidase activity
EB239_RS11385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB239_RS11390	COG3328	transposase activity
EB239_RS11450	COG1461	Dihydroxyacetone kinase
EB239_RS11455	COG2376	Dihydroxyacetone kinase
EB239_RS11465	COG1070	Carbohydrate kinase
EB239_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
EB239_RS11500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB239_RS11510	COG0613	PHP domain protein
EB239_RS11515	COG0546	phosphoglycolate phosphatase activity
EB239_RS11520	COG0698	ribose 5-phosphate isomerase
EB239_RS11525	COG3958	Transketolase
EB239_RS11530	COG3959	Transketolase, thiamine diphosphate binding domain
EB239_RS11535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB239_RS11555	COG0564	pseudouridine synthase activity
EB239_RS11575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EB239_RS11580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EB239_RS11590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EB239_RS11595	COG0463	Glycosyl transferase, family 2
EB239_RS11635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EB239_RS11650	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EB239_RS11665	COG3546	catalase activity
EB239_RS11670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EB239_RS11675	COG1410	methionine synthase
EB239_RS11675	COG0646	methionine synthase
EB239_RS11680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EB239_RS11680	COG0646	methionine synthase
EB239_RS11690	COG0058	SHG alpha-glucan phosphorylase activity
EB239_RS11710	COG0166	Belongs to the GPI family
EB239_RS11720	COG0778	Nitroreductase
EB239_RS11725	COG2195	Cleaves the N-terminal amino acid of tripeptides
EB239_RS11730	COG3344	reverse transcriptase
EB239_RS11750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB239_RS11755	COG0534	Mate efflux family protein
EB239_RS11770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EB239_RS11820	COG4109	DRTGG domain
EB239_RS11825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS11830	COG1481	regulation of sporulation
EB239_RS11840	COG0366	Alpha amylase catalytic
EB239_RS11845	COG1426	Protein conserved in bacteria
EB239_RS11865	COG3833	ABC-type maltose transport systems, permease component
EB239_RS11870	COG1175	transmembrane transport
EB239_RS11875	COG2182	Extracellular solute-binding protein
EB239_RS11900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EB239_RS11905	COG1752	Esterase of the alpha-beta hydrolase superfamily
EB239_RS11910	COG1309	transcriptional regulator
EB239_RS11915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EB239_RS11935	COG3344	reverse transcriptase
EB239_RS11955	COG0671	phosphoesterase, PA-phosphatase related
EB239_RS11965	COG2217	Heavy metal translocating P-type atpase
EB239_RS11985	COG1733	regulation of RNA biosynthetic process
EB239_RS11990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EB239_RS12005	COG2608	mercury ion transmembrane transporter activity
EB239_RS12010	COG0586	Pfam SNARE associated Golgi protein
EB239_RS12015	COG1342	Belongs to the UPF0251 family
EB239_RS12020	COG5001	Diguanylate cyclase
EB239_RS12020	COG5002	protein histidine kinase activity
EB239_RS12020	COG3447	MASE1 domain protein
EB239_RS12025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB239_RS12060	COG1120	ATPase activity
EB239_RS12065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB239_RS12080	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB239_RS12095	COG1234	tRNA 3'-trailer cleavage
EB239_RS12105	COG0489	protein tyrosine kinase activity
EB239_RS12110	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EB239_RS12130	COG2226	methyltransferase
EB239_RS12145	COG1609	Transcriptional regulator
EB239_RS12150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB239_RS12155	COG1621	beta-fructofuranosidase activity
EB239_RS12170	COG2182	Extracellular solute-binding protein
EB239_RS12200	COG0768	penicillin binding
EB239_RS12230	COG5564	TIM-barrel signal transduction protein
EB239_RS12240	COG5564	TIM-barrel signal transduction protein
EB239_RS12240	COG2204	response regulator
EB239_RS12250	COG0531	amino acid
EB239_RS12255	COG0653	protein targeting
EB239_RS12270	COG0842	Transport permease protein
EB239_RS12275	COG1131	(ABC) transporter
EB239_RS12285	COG3250	beta-galactosidase activity
EB239_RS12300	COG4211	Belongs to the binding-protein-dependent transport system permease family
EB239_RS12325	COG1940	carbohydrate kinase activity
EB239_RS12330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EB239_RS12335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EB239_RS12340	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EB239_RS12345	COG3464	Transposase
EB239_RS12355	COG0800	Aldolase
EB239_RS12360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB239_RS12365	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EB239_RS12370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB239_RS12375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS12375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB239_RS12380	COG3716	PTS system mannose fructose sorbose family IID component
EB239_RS12395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS12395	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB239_RS12405	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EB239_RS12405	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EB239_RS12410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EB239_RS12420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB239_RS12425	COG1349	DNA-binding transcription factor activity
EB239_RS12435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EB239_RS12455	COG0673	inositol 2-dehydrogenase activity
EB239_RS12460	COG0673	inositol 2-dehydrogenase activity
EB239_RS12505	COG3885	ferrous iron binding
EB239_RS12505	COG2078	PFAM AMMECR1 domain protein
EB239_RS12520	COG0318	PFAM AMP-dependent synthetase and ligase
EB239_RS12550	COG0768	penicillin binding
EB239_RS12570	COG0556	nucleotide-excision repair
EB239_RS12585	COG2045	Belongs to the ComB family
EB239_RS12590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB239_RS12595	COG0793	Belongs to the peptidase S41A family
EB239_RS12595	COG3409	Peptidoglycan-binding domain 1 protein
EB239_RS12600	COG0739	heme binding
EB239_RS12605	COG2177	Part of the ABC transporter FtsEX involved in
EB239_RS12610	COG2884	Cell division ATP-binding protein ftsE
EB239_RS12615	COG3835	regulator
EB239_RS12620	COG3842	ATPase activity
EB239_RS12635	COG3328	transposase activity
EB239_RS12650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EB239_RS12660	COG0849	cell division
EB239_RS12665	COG4166	transmembrane transport
EB239_RS12705	COG0443	Heat shock 70 kDa protein
EB239_RS12710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EB239_RS12720	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EB239_RS12720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB239_RS12720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS12730	COG2376	Dihydroxyacetone kinase
EB239_RS12745	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB239_RS12755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB239_RS12760	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB239_RS12765	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EB239_RS12795	COG2205	protein histidine kinase activity
EB239_RS12800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EB239_RS12805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EB239_RS12810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EB239_RS12820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EB239_RS12830	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EB239_RS12835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EB239_RS12860	COG3344	reverse transcriptase
EB239_RS12865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EB239_RS12865	COG0140	phosphoribosyl-ATP diphosphatase activity
EB239_RS12880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EB239_RS12885	COG0131	Imidazoleglycerol-phosphate dehydratase
EB239_RS12895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB239_RS12920	COG3547	Transposase (IS116 IS110 IS902 family)
EB239_RS12940	COG0673	inositol 2-dehydrogenase activity
EB239_RS12955	COG1879	ABC-type sugar transport system periplasmic component
EB239_RS12960	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB239_RS12965	COG1129	ABC transporter
EB239_RS12990	COG1131	(ABC) transporter
EB239_RS12995	COG3459	Glycosyltransferase 36 associated
EB239_RS13000	COG0598	Magnesium transport protein CorA
EB239_RS13005	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EB239_RS13005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB239_RS13010	COG0673	inositol 2-dehydrogenase activity
EB239_RS13015	COG3344	reverse transcriptase
EB239_RS13025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB239_RS13030	COG2873	o-acetylhomoserine
EB239_RS13035	COG0460	homoserine dehydrogenase
EB239_RS13040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EB239_RS13045	COG1773	rubredoxin
EB239_RS13050	COG2205	protein histidine kinase activity
EB239_RS13055	COG1757	Na H antiporter
EB239_RS13060	COG0205	6-phosphofructokinase activity
EB239_RS13085	COG3958	Transketolase
EB239_RS13090	COG3959	Transketolase, thiamine diphosphate binding domain
EB239_RS13095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB239_RS13120	COG2337	Toxic component of a toxin-antitoxin (TA) module
EB239_RS13130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EB239_RS13140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EB239_RS13140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EB239_RS13175	COG1971	Probably functions as a manganese efflux pump
EB239_RS13180	COG0450	alkyl hydroperoxide reductase
EB239_RS13190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EB239_RS13195	COG1793	dna ligase
EB239_RS13200	COG0432	Pfam Uncharacterised protein family UPF0047
EB239_RS13210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB239_RS13220	COG0318	PFAM AMP-dependent synthetase and ligase
EB239_RS13220	COG0204	Acyl-transferase
EB239_RS13235	COG0280	phosphate acetyltransferase
EB239_RS13265	COG3426	butyrate kinase activity
EB239_RS13275	COG0280	phosphate acetyltransferase
EB239_RS13280	COG3426	butyrate kinase activity
EB239_RS13290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EB239_RS13305	COG1305	Transglutaminase-like
EB239_RS13315	COG0714	Associated with various cellular activities
EB239_RS13330	COG0546	phosphoglycolate phosphatase activity
EB239_RS13340	COG1388	LysM domain
EB239_RS13340	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB239_RS13380	COG0708	Exodeoxyribonuclease III
EB239_RS13385	COG2033	superoxide reductase activity
EB239_RS13400	COG0840	transmembrane signaling receptor activity
EB239_RS13405	COG3300	MHYT domain
EB239_RS13405	COG5001	Diguanylate cyclase
EB239_RS13415	COG2201	protein-glutamate methylesterase activity
EB239_RS13420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EB239_RS13435	COG0643	Histidine kinase
EB239_RS13435	COG2198	Histidine kinase
EB239_RS13440	COG0835	chemotaxis
EB239_RS13445	COG2201	protein-glutamate methylesterase activity
EB239_RS13455	COG2801	Transposase and inactivated derivatives
EB239_RS13490	COG2059	Chromate
EB239_RS13520	COG0640	Transcriptional regulator
EB239_RS13545	COG1475	DNA binding
EB239_RS13600	COG0582	viral genome integration into host DNA
EB239_RS13675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EB239_RS13680	COG1122	ATPase activity
EB239_RS13685	COG1122	ATPase activity
EB239_RS13705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EB239_RS13720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EB239_RS13740	COG0201	protein transport
EB239_RS13760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EB239_RS13805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EB239_RS13835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EB239_RS13845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB239_RS13855	COG0049	tRNA binding
EB239_RS13860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EB239_RS13865	COG1358	cellular component organization or biogenesis
EB239_RS13870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EB239_RS13875	COG0085	RNA polymerase activity
EB239_RS13880	COG0222	ribosome binding
EB239_RS13890	COG0081	regulation of translation
EB239_RS13900	COG0250	Participates in transcription elongation, termination and antitermination
EB239_RS13905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB239_RS13910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB239_RS13915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB239_RS13930	COG3688	RNA-binding protein containing a PIN domain
EB239_RS13935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB239_RS13950	COG1045	serine acetyltransferase
EB239_RS13965	COG0442	prolyl-tRNA aminoacylation
EB239_RS13970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EB239_RS13980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EB239_RS13985	COG4956	integral membrane protein (PIN domain superfamily)
EB239_RS13995	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EB239_RS14000	COG1914	H( )-stimulated, divalent metal cation uptake system
EB239_RS14010	COG3344	reverse transcriptase
EB239_RS14020	COG0542	response to heat
EB239_RS14025	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EB239_RS14030	COG3880	PFAM UvrB UvrC protein
EB239_RS14045	COG0281	malic enzyme
EB239_RS14050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB239_RS14060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB239_RS14070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS14070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB239_RS14070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB239_RS14075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB239_RS14075	COG3711	transcriptional antiterminator
EB239_RS14100	COG4224	UPF0291 protein
EB239_RS14110	COG0823	Involved in the tonB-independent uptake of proteins
EB239_RS14110	COG1506	peptidase
EB239_RS14110	COG4946	Tricorn protease homolog
EB239_RS14120	COG0720	synthase
EB239_RS14125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EB239_RS14130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EB239_RS14155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EB239_RS14155	COG5322	oxidoreductase activity
EB239_RS14185	COG0697	spore germination
EB239_RS14190	COG0531	amino acid
EB239_RS14200	COG4684	Psort location CytoplasmicMembrane, score
EB239_RS14205	COG4770	biotin carboxylase activity
EB239_RS14215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB239_RS14220	COG0346	lactoylglutathione lyase activity
EB239_RS14230	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB239_RS14230	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB239_RS14235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB239_RS14235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EB239_RS14250	COG3852	Histidine kinase
EB239_RS14260	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EB239_RS14265	COG0037	tRNA processing
EB239_RS14275	COG2208	phosphoserine phosphatase activity
EB239_RS14285	COG2226	methyltransferase
EB239_RS14290	COG0697	spore germination
EB239_RS14295	COG1595	DNA-templated transcription, initiation
EB239_RS14305	COG1131	(ABC) transporter
EB239_RS14335	COG1063	alcohol dehydrogenase
EB239_RS14340	COG0156	8-amino-7-oxononanoate synthase activity
EB239_RS14375	COG2267	carboxylic ester hydrolase activity
EB239_RS14390	COG2151	metal-sulfur cluster biosynthetic enzyme
EB239_RS14395	COG3344	reverse transcriptase
EB239_RS14415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB239_RS14420	COG0022	dehydrogenase e1 component
EB239_RS14425	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB239_RS14435	COG3706	GGDEF domain
EB239_RS14450	COG5001	Diguanylate cyclase
EB239_RS14450	COG3300	MHYT domain