locus-tag	class	description
TETH514_RS00010	COG0592	DNA-directed DNA polymerase activity
TETH514_RS00015	COG2501	S4 domain
TETH514_RS00035	COG3442	glutamine amidotransferase
TETH514_RS00045	COG0187	DNA topoisomerase II activity
TETH514_RS00050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TETH514_RS00055	COG1902	pentaerythritol trinitrate reductase activity
TETH514_RS00060	COG0440	acetolactate synthase activity
TETH514_RS00070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TETH514_RS00080	COG0066	3-isopropylmalate dehydratase activity
TETH514_RS00085	COG0473	3-isopropylmalate dehydrogenase activity
TETH514_RS00090	COG0129	dihydroxy-acid dehydratase activity
TETH514_RS00095	COG0028	Belongs to the TPP enzyme family
TETH514_RS00120	COG0628	permease
TETH514_RS00175	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TETH514_RS00175	COG2199	diguanylate cyclase activity
TETH514_RS00180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TETH514_RS00195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TETH514_RS00200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TETH514_RS00205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TETH514_RS00245	COG0583	DNA-binding transcription factor activity
TETH514_RS00250	COG2391	methyltransferase activity
TETH514_RS00260	COG2391	methyltransferase activity
TETH514_RS00275	COG0519	Catalyzes the synthesis of GMP from XMP
TETH514_RS00285	COG1982	Orn Lys Arg decarboxylase major
TETH514_RS00295	COG3870	Protein conserved in bacteria
TETH514_RS00305	COG0470	DNA polymerase III
TETH514_RS00310	COG1774	PSP1 C-terminal conserved region
TETH514_RS00315	COG2235	arginine
TETH514_RS00320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TETH514_RS00325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TETH514_RS00335	COG2002	toxin-antitoxin pair type II binding
TETH514_RS00340	COG2715	membrane protein required for spore maturation
TETH514_RS00345	COG0700	Nucleoside recognition
TETH514_RS00350	COG0617	tRNA 3'-terminal CCA addition
TETH514_RS00355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TETH514_RS00355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TETH514_RS00360	COG0084	hydrolase, TatD family'
TETH514_RS00365	COG3583	domain protein
TETH514_RS00365	COG3584	3D domain protein
TETH514_RS00370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TETH514_RS00390	COG4447	cellulose binding
TETH514_RS00395	COG1191	sigma factor activity
TETH514_RS00400	COG0489	protein tyrosine kinase activity
TETH514_RS00400	COG2151	metal-sulfur cluster biosynthetic enzyme
TETH514_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TETH514_RS00420	COG4656	Part of a membrane complex involved in electron transport
TETH514_RS00425	COG4658	electron transport chain
TETH514_RS00430	COG4659	FMN binding
TETH514_RS00435	COG4660	Part of a membrane complex involved in electron transport
TETH514_RS00440	COG4657	Part of a membrane complex involved in electron transport
TETH514_RS00445	COG1245	4Fe-4S binding domain
TETH514_RS00445	COG2878	Part of a membrane complex involved in electron transport
TETH514_RS00455	COG0745	RESPONSE REGULATOR receiver
TETH514_RS00465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TETH514_RS00480	COG3872	metal-dependent enzyme
TETH514_RS00495	COG0428	transporter
TETH514_RS00500	COG0009	L-threonylcarbamoyladenylate synthase
TETH514_RS00505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TETH514_RS00510	COG0698	ribose 5-phosphate isomerase
TETH514_RS00535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TETH514_RS00540	COG0686	Belongs to the AlaDH PNT family
TETH514_RS00550	COG2385	sporulation resulting in formation of a cellular spore
TETH514_RS00560	COG1609	Transcriptional regulator
TETH514_RS00570	COG4786	Flagellar basal body rod
TETH514_RS00600	COG1496	oxidoreductase activity
TETH514_RS00615	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TETH514_RS00615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TETH514_RS00630	COG3775	system Galactitol-specific IIC component
TETH514_RS00650	COG4948	Mandelate Racemase Muconate Lactonizing
TETH514_RS00655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TETH514_RS00660	COG0800	Aldolase
TETH514_RS00665	COG2814	Major facilitator Superfamily
TETH514_RS00670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TETH514_RS00670	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TETH514_RS00675	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS00685	COG3716	PTS system mannose fructose sorbose family IID component
TETH514_RS00690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TETH514_RS00695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TETH514_RS00700	COG0800	Aldolase
TETH514_RS00705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TETH514_RS00710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TETH514_RS00715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TETH514_RS00720	COG0569	domain protein
TETH514_RS00735	COG0778	Nitroreductase
TETH514_RS00750	COG0583	DNA-binding transcription factor activity
TETH514_RS00780	COG1070	Carbohydrate kinase
TETH514_RS00785	COG4213	ABC transporter substrate-binding protein
TETH514_RS00790	COG3344	reverse transcriptase
TETH514_RS00800	COG4214	carbohydrate transport
TETH514_RS00815	COG1609	Transcriptional regulator
TETH514_RS00820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TETH514_RS00830	COG1129	ABC transporter
TETH514_RS00835	COG1172	Belongs to the binding-protein-dependent transport system permease family
TETH514_RS00840	COG1879	ABC-type sugar transport system periplasmic component
TETH514_RS00845	COG3344	reverse transcriptase
TETH514_RS00850	COG1737	Transcriptional regulator
TETH514_RS00860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TETH514_RS00860	COG1263	PTS System
TETH514_RS00875	COG2188	Transcriptional regulator
TETH514_RS00900	COG1735	metal-dependent hydrolase with the TIM-barrel fold
TETH514_RS00905	COG0626	cystathionine gamma-synthase activity
TETH514_RS00910	COG3457	Alanine racemase
TETH514_RS00915	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TETH514_RS00920	COG1472	Belongs to the glycosyl hydrolase 3 family
TETH514_RS00935	COG0436	Aminotransferase
TETH514_RS00940	COG1522	sequence-specific DNA binding
TETH514_RS00950	COG1918	ferrous iron import across plasma membrane
TETH514_RS00950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TETH514_RS00955	COG1122	ATPase activity
TETH514_RS00960	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TETH514_RS00965	COG0310	cobalt ion transport
TETH514_RS00970	COG0310	cobalt ion transport
TETH514_RS00975	COG0864	Transcriptional regulator
TETH514_RS00985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TETH514_RS01005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TETH514_RS01010	COG1136	(ABC) transporter
TETH514_RS01015	COG0577	efflux transmembrane transporter activity
TETH514_RS01015	COG1136	(ABC) transporter
TETH514_RS01020	COG0179	Fumarylacetoacetate (FAA) hydrolase
TETH514_RS01040	COG0420	3'-5' exonuclease activity
TETH514_RS01045	COG0419	ATPase involved in DNA repair
TETH514_RS01055	COG0450	alkyl hydroperoxide reductase
TETH514_RS01080	COG0297	glycogen (starch) synthase activity
TETH514_RS01125	COG1980	fructose-bisphosphate aldolase activity
TETH514_RS01125	COG1980	fructose-bisphosphate aldolase activity
TETH514_RS01135	COG2972	Histidine kinase
TETH514_RS01140	COG2197	response regulator
TETH514_RS01145	COG4213	ABC transporter substrate-binding protein
TETH514_RS01150	COG4213	ABC transporter substrate-binding protein
TETH514_RS01155	COG1129	ABC transporter
TETH514_RS01160	COG4214	carbohydrate transport
TETH514_RS01165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TETH514_RS01170	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TETH514_RS01185	COG0095	Lipoate-protein ligase
TETH514_RS01190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TETH514_RS01200	COG0436	Aminotransferase
TETH514_RS01210	COG3037	sugar-specific permease SgaT UlaA
TETH514_RS01225	COG1979	alcohol dehydrogenase
TETH514_RS01245	COG0640	Transcriptional regulator
TETH514_RS01275	COG1924	4 iron, 4 sulfur cluster binding
TETH514_RS01285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TETH514_RS01290	COG0390	transport system, permease component
TETH514_RS01295	COG0495	leucyl-tRNA aminoacylation
TETH514_RS01300	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
TETH514_RS01310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TETH514_RS01310	COG1522	sequence-specific DNA binding
TETH514_RS01315	COG2313	pseudouridylate synthase activity
TETH514_RS01325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TETH514_RS01325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TETH514_RS01345	COG1447	Phosphotransferase system cellobiose-specific component IIA
TETH514_RS01350	COG1486	melibiose metabolic process
TETH514_RS01355	COG2723	6-phospho-beta-galactosidase activity
TETH514_RS01360	COG2213	PTS system mannitol-specific
TETH514_RS01365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS01365	COG3711	transcriptional antiterminator
TETH514_RS01380	COG0737	Belongs to the 5'-nucleotidase family
TETH514_RS01385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TETH514_RS01390	COG0730	response to heat
TETH514_RS01400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TETH514_RS01405	COG1121	(ABC) transporter
TETH514_RS01410	COG0803	Belongs to the bacterial solute-binding protein 9 family
TETH514_RS01415	COG0735	belongs to the Fur family
TETH514_RS01420	COG0714	Associated with various cellular activities
TETH514_RS01435	COG1704	LemA family
TETH514_RS01440	COG0583	DNA-binding transcription factor activity
TETH514_RS01465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TETH514_RS01470	COG0822	iron-sulfur transferase activity
TETH514_RS01485	COG0116	Belongs to the methyltransferase superfamily
TETH514_RS01500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TETH514_RS01505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TETH514_RS01510	COG1120	ATPase activity
TETH514_RS01515	COG1797	cobyrinic acid a,c-diamide synthase activity
TETH514_RS01540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TETH514_RS01605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TETH514_RS01620	COG0113	porphobilinogen synthase activity
TETH514_RS01625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TETH514_RS01630	COG0310	cobalt ion transport
TETH514_RS01645	COG1122	ATPase activity
TETH514_RS01660	COG4555	ABC transporter
TETH514_RS01715	COG4555	ABC transporter
TETH514_RS01720	COG1668	transmembrane transport
TETH514_RS01745	COG1131	(ABC) transporter
TETH514_RS01755	COG4566	intracellular signal transduction
TETH514_RS01765	COG1131	(ABC) transporter
TETH514_RS01825	COG4555	ABC transporter
TETH514_RS01830	COG1668	transmembrane transport
TETH514_RS01865	COG1131	(ABC) transporter
TETH514_RS01890	COG1363	Peptidase, m42
TETH514_RS01920	COG3344	reverse transcriptase
TETH514_RS01930	COG2199	diguanylate cyclase activity
TETH514_RS01930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TETH514_RS01940	COG0840	transmembrane signaling receptor activity
TETH514_RS01950	COG1228	amidohydrolase
TETH514_RS01965	COG1486	melibiose metabolic process
TETH514_RS01980	COG1653	transport
TETH514_RS01985	COG2972	Histidine kinase
TETH514_RS01990	COG4753	response regulator
TETH514_RS01990	COG2207	Transcriptional regulator
TETH514_RS01995	COG3404	Formiminotransferase-cyclodeaminase
TETH514_RS02000	COG1744	ABC transporter substrate-binding protein PnrA-like
TETH514_RS02005	COG3845	ABC transporter
TETH514_RS02010	COG4603	Belongs to the binding-protein-dependent transport system permease family
TETH514_RS02015	COG1079	Belongs to the binding-protein-dependent transport system permease family
TETH514_RS02040	COG0840	transmembrane signaling receptor activity
TETH514_RS02050	COG1263	PTS System
TETH514_RS02050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TETH514_RS02050	COG2190	(PTS) system
TETH514_RS02055	COG2190	(PTS) system
TETH514_RS02060	COG3711	transcriptional antiterminator
TETH514_RS02065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TETH514_RS02110	COG2081	HI0933 family
TETH514_RS02135	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TETH514_RS02140	COG4974	Belongs to the 'phage' integrase family
TETH514_RS02150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TETH514_RS02155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TETH514_RS02170	COG2323	membrane
TETH514_RS02175	COG0561	phosphatase activity
TETH514_RS02180	COG1609	Transcriptional regulator
TETH514_RS02185	COG0745	RESPONSE REGULATOR receiver
TETH514_RS02190	COG5002	protein histidine kinase activity
TETH514_RS02225	COG1592	Rubrerythrin
TETH514_RS02230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TETH514_RS02235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TETH514_RS02240	COG1040	competence protein
TETH514_RS02260	COG1256	bacterial-type flagellum assembly
TETH514_RS02260	COG4786	Flagellar basal body rod
TETH514_RS02265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TETH514_RS02275	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TETH514_RS02280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TETH514_RS02310	COG0367	asparagine synthase
TETH514_RS02325	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TETH514_RS02330	COG1516	flagellar protein fliS
TETH514_RS02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TETH514_RS02350	COG0765	amino acid transport
TETH514_RS02380	COG1827	regulation of RNA biosynthetic process
TETH514_RS02390	COG0653	protein targeting
TETH514_RS02395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TETH514_RS02400	COG2183	response to ionizing radiation
TETH514_RS02410	COG0398	Pfam SNARE associated Golgi protein
TETH514_RS02420	COG2235	arginine
TETH514_RS02425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TETH514_RS02430	COG0549	Belongs to the carbamate kinase family
TETH514_RS02440	COG3344	reverse transcriptase
TETH514_RS02445	COG0802	atpase or kinase
TETH514_RS02450	COG1214	PFAM Peptidase M22, glycoprotease
TETH514_RS02460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TETH514_RS02470	COG0488	(ABC) transporter
TETH514_RS02495	COG3279	Response regulator of the LytR AlgR family
TETH514_RS02500	COG3290	protein histidine kinase activity
TETH514_RS02535	COG1811	Na channel or pump
TETH514_RS02545	COG1404	Belongs to the peptidase S8 family
TETH514_RS02580	COG0516	GMP reductase activity
TETH514_RS02580	COG0517	IMP dehydrogenase activity
TETH514_RS02585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TETH514_RS02585	COG0519	Catalyzes the synthesis of GMP from XMP
TETH514_RS02590	COG2252	PERMEase
TETH514_RS02595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TETH514_RS02605	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TETH514_RS02610	COG0047	phosphoribosylformylglycinamidine synthase activity
TETH514_RS02620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TETH514_RS02630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TETH514_RS02640	COG0151	Belongs to the GarS family
TETH514_RS02650	COG1473	amidohydrolase
TETH514_RS02655	COG2244	polysaccharide biosynthetic process
TETH514_RS02665	COG3711	transcriptional antiterminator
TETH514_RS02675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TETH514_RS02680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TETH514_RS02685	COG1447	Phosphotransferase system cellobiose-specific component IIA
TETH514_RS02690	COG4496	protein, YerC YecD
TETH514_RS02695	COG0210	DNA helicase
TETH514_RS02735	COG4166	transmembrane transport
TETH514_RS02740	COG0601	transmembrane transport
TETH514_RS02745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TETH514_RS02750	COG0444	Belongs to the ABC transporter superfamily
TETH514_RS02755	COG4608	Belongs to the ABC transporter superfamily
TETH514_RS02830	COG0004	ammonium transporteR
TETH514_RS02835	COG0347	Belongs to the P(II) protein family
TETH514_RS02840	COG0505	Belongs to the CarA family
TETH514_RS02845	COG0067	glutamate synthase
TETH514_RS02855	COG0437	4 iron, 4 sulfur cluster binding
TETH514_RS02870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TETH514_RS02880	COG0351	phosphomethylpyrimidine kinase
TETH514_RS02885	COG0352	thiamine-phosphate diphosphorylase activity
TETH514_RS02905	COG0704	Plays a role in the regulation of phosphate uptake
TETH514_RS02930	COG1349	DNA-binding transcription factor activity
TETH514_RS02940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS02940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS02940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS02955	COG0071	Belongs to the small heat shock protein (HSP20) family
TETH514_RS02965	COG1609	Transcriptional regulator
TETH514_RS02970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TETH514_RS02975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TETH514_RS02985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TETH514_RS02990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TETH514_RS02995	COG0745	RESPONSE REGULATOR receiver
TETH514_RS03000	COG5002	protein histidine kinase activity
TETH514_RS03005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TETH514_RS03020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TETH514_RS03025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TETH514_RS03030	COG2002	toxin-antitoxin pair type II binding
TETH514_RS03040	COG4466	Protein conserved in bacteria
TETH514_RS03045	COG1388	LysM domain
TETH514_RS03055	COG1802	Transcriptional regulator
TETH514_RS03070	COG0697	spore germination
TETH514_RS03075	COG0531	amino acid
TETH514_RS03095	COG2959	enzyme of heme biosynthesis
TETH514_RS03115	COG0018	arginyl-trna synthetase
TETH514_RS03120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TETH514_RS03130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TETH514_RS03150	COG4608	Belongs to the ABC transporter superfamily
TETH514_RS03155	COG0444	Belongs to the ABC transporter superfamily
TETH514_RS03160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TETH514_RS03165	COG0601	transmembrane transport
TETH514_RS03170	COG4166	transmembrane transport
TETH514_RS03180	COG0667	Aldo Keto reductase
TETH514_RS03190	COG1012	belongs to the aldehyde dehydrogenase family
TETH514_RS03190	COG1454	alcohol dehydrogenase
TETH514_RS03200	COG1846	Transcriptional regulator
TETH514_RS03210	COG1132	(ABC) transporter
TETH514_RS03215	COG3859	Proton-coupled thiamine transporter YuaJ
TETH514_RS03220	COG0671	phosphoesterase, PA-phosphatase related
TETH514_RS03275	COG1595	DNA-templated transcription, initiation
TETH514_RS03295	COG1131	(ABC) transporter
TETH514_RS03305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TETH514_RS03305	COG1796	DNA polymerase
TETH514_RS03310	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TETH514_RS03310	COG0493	'glutamate synthase
TETH514_RS03345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TETH514_RS03355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TETH514_RS03360	COG0505	Belongs to the CarA family
TETH514_RS03380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TETH514_RS03395	COG1528	Iron-storage protein
TETH514_RS03415	COG0142	geranyltranstransferase activity
TETH514_RS03445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TETH514_RS03455	COG2033	superoxide reductase activity
TETH514_RS03460	COG5002	protein histidine kinase activity
TETH514_RS03465	COG1027	Aspartate ammonia-lyase
TETH514_RS03470	COG1160	GTP binding
TETH514_RS03475	COG2814	Major facilitator Superfamily
TETH514_RS03485	COG3956	TIGRFAM MazG family protein
TETH514_RS03490	COG0776	regulation of translation
TETH514_RS03495	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TETH514_RS03500	COG2385	sporulation resulting in formation of a cellular spore
TETH514_RS03535	COG1098	S1 RNA binding domain
TETH514_RS03540	COG0248	Ppx GppA phosphatase
TETH514_RS03540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TETH514_RS03580	COG1396	sequence-specific DNA binding
TETH514_RS03655	COG0739	heme binding
TETH514_RS03680	COG4962	Type ii secretion system protein e
TETH514_RS03810	COG5001	Diguanylate cyclase
TETH514_RS03810	COG3300	MHYT domain
TETH514_RS03820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TETH514_RS03825	COG3344	reverse transcriptase
TETH514_RS03840	COG1940	carbohydrate kinase activity
TETH514_RS03845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TETH514_RS03850	COG1175	transmembrane transport
TETH514_RS03860	COG0395	ABC-type sugar transport system, permease component
TETH514_RS03870	COG3387	PFAM Glycoside hydrolase 15-related
TETH514_RS03885	COG2801	Transposase and inactivated derivatives
TETH514_RS03900	COG0745	RESPONSE REGULATOR receiver
TETH514_RS03905	COG2205	protein histidine kinase activity
TETH514_RS03920	COG2217	Heavy metal translocating P-type atpase
TETH514_RS03925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TETH514_RS03940	COG2217	Heavy metal translocating P-type atpase
TETH514_RS03945	COG3300	MHYT domain
TETH514_RS03945	COG5001	Diguanylate cyclase
TETH514_RS03970	COG1063	alcohol dehydrogenase
TETH514_RS03990	COG1131	(ABC) transporter
TETH514_RS04005	COG0697	spore germination
TETH514_RS04015	COG2208	phosphoserine phosphatase activity
TETH514_RS04020	COG0037	tRNA processing
TETH514_RS04025	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TETH514_RS04035	COG3852	Histidine kinase
TETH514_RS04050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TETH514_RS04060	COG5016	pyruvate
TETH514_RS04060	COG0511	ligase activity, forming carbon-carbon bonds
TETH514_RS04065	COG4684	Psort location CytoplasmicMembrane, score
TETH514_RS04075	COG0531	amino acid
TETH514_RS04080	COG0697	spore germination
TETH514_RS04105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TETH514_RS04105	COG5322	oxidoreductase activity
TETH514_RS04125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TETH514_RS04130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TETH514_RS04135	COG0720	synthase
TETH514_RS04145	COG4946	Tricorn protease homolog
TETH514_RS04145	COG0823	Involved in the tonB-independent uptake of proteins
TETH514_RS04145	COG1506	peptidase
TETH514_RS04180	COG3711	transcriptional antiterminator
TETH514_RS04180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS04185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS04185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS04190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS04190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS04190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS04195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TETH514_RS04200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TETH514_RS04205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TETH514_RS04210	COG3344	reverse transcriptase
TETH514_RS04215	COG0281	malic enzyme
TETH514_RS04235	COG3880	PFAM UvrB UvrC protein
TETH514_RS04240	COG3869	Catalyzes the specific phosphorylation of arginine residues in
TETH514_RS04245	COG0542	response to heat
TETH514_RS04250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TETH514_RS04260	COG4956	integral membrane protein (PIN domain superfamily)
TETH514_RS04265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TETH514_RS04275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TETH514_RS04295	COG1045	serine acetyltransferase
TETH514_RS04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TETH514_RS04315	COG3688	RNA-binding protein containing a PIN domain
TETH514_RS04320	COG1595	DNA-templated transcription, initiation
TETH514_RS04330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TETH514_RS04340	COG0250	Participates in transcription elongation, termination and antitermination
TETH514_RS04375	COG1358	cellular component organization or biogenesis
TETH514_RS04380	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TETH514_RS04395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TETH514_RS04435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TETH514_RS04500	COG0201	protein transport
TETH514_RS04520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TETH514_RS04555	COG1122	ATPase activity
TETH514_RS04560	COG1122	ATPase activity
TETH514_RS04565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TETH514_RS04635	COG2033	superoxide reductase activity
TETH514_RS04655	COG1966	Carbon starvation protein
TETH514_RS04660	COG1115	amino acid carrier protein
TETH514_RS04665	COG1863	multisubunit Na H antiporter MnhE subunit
TETH514_RS04675	COG1320	monovalent cation:proton antiporter activity
TETH514_RS04695	COG0651	ATP synthesis coupled electron transport
TETH514_RS04700	COG0651	ATP synthesis coupled electron transport
TETH514_RS04710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TETH514_RS04735	COG1705	Flagellar rod assembly protein muramidase FlgJ
TETH514_RS04735	COG1388	LysM domain
TETH514_RS04745	COG0546	phosphoglycolate phosphatase activity
TETH514_RS04750	COG0714	Associated with various cellular activities
TETH514_RS04760	COG1305	Transglutaminase-like
TETH514_RS04780	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TETH514_RS04790	COG3426	butyrate kinase activity
TETH514_RS04795	COG0280	phosphate acetyltransferase
TETH514_RS04805	COG3426	butyrate kinase activity
TETH514_RS04835	COG0280	phosphate acetyltransferase
TETH514_RS04850	COG0318	PFAM AMP-dependent synthetase and ligase
TETH514_RS04850	COG0204	Acyl-transferase
TETH514_RS04860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TETH514_RS04865	COG0432	Pfam Uncharacterised protein family UPF0047
TETH514_RS04870	COG1793	dna ligase
TETH514_RS04875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
TETH514_RS04920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TETH514_RS04920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TETH514_RS04930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TETH514_RS04940	COG2337	Toxic component of a toxin-antitoxin (TA) module
TETH514_RS04945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TETH514_RS04950	COG3959	Transketolase, thiamine diphosphate binding domain
TETH514_RS04955	COG3958	Transketolase
TETH514_RS04965	COG0205	6-phosphofructokinase activity
TETH514_RS04970	COG1757	Na H antiporter
TETH514_RS04975	COG1773	rubredoxin
TETH514_RS04985	COG0460	homoserine dehydrogenase
TETH514_RS04990	COG2873	o-acetylhomoserine
TETH514_RS04995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TETH514_RS05000	COG0673	inositol 2-dehydrogenase activity
TETH514_RS05005	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TETH514_RS05005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TETH514_RS05010	COG3459	Glycosyltransferase 36 associated
TETH514_RS05015	COG1131	(ABC) transporter
TETH514_RS05040	COG1082	Xylose isomerase domain protein TIM barrel
TETH514_RS05050	COG0673	inositol 2-dehydrogenase activity
TETH514_RS05060	COG1172	Belongs to the binding-protein-dependent transport system permease family
TETH514_RS05075	COG0673	inositol 2-dehydrogenase activity
TETH514_RS05110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TETH514_RS05125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TETH514_RS05140	COG0140	phosphoribosyl-ATP diphosphatase activity
TETH514_RS05140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TETH514_RS05155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TETH514_RS05160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TETH514_RS05170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TETH514_RS05190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
TETH514_RS05195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TETH514_RS05210	COG0446	pyridine nucleotide-disulphide oxidoreductase
TETH514_RS05225	COG2376	Dihydroxyacetone kinase
TETH514_RS05235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TETH514_RS05235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS05235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
TETH514_RS05245	COG0443	Heat shock 70 kDa protein
TETH514_RS05280	COG0849	cell division
TETH514_RS05300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TETH514_RS05315	COG0019	diaminopimelate decarboxylase activity
TETH514_RS05325	COG3842	ATPase activity
TETH514_RS05330	COG3835	regulator
TETH514_RS05335	COG2884	Cell division ATP-binding protein ftsE
TETH514_RS05340	COG2177	Part of the ABC transporter FtsEX involved in
TETH514_RS05345	COG0739	heme binding
TETH514_RS05350	COG3409	Peptidoglycan-binding domain 1 protein
TETH514_RS05350	COG0793	Belongs to the peptidase S41A family
TETH514_RS05355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TETH514_RS05360	COG2045	Belongs to the ComB family
TETH514_RS05365	COG0556	nucleotide-excision repair
TETH514_RS05385	COG0768	penicillin binding
TETH514_RS05415	COG0318	PFAM AMP-dependent synthetase and ligase
TETH514_RS05430	COG2078	PFAM AMMECR1 domain protein
TETH514_RS05430	COG3885	ferrous iron binding
TETH514_RS05475	COG0673	inositol 2-dehydrogenase activity
TETH514_RS05480	COG0673	inositol 2-dehydrogenase activity
TETH514_RS05500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TETH514_RS05505	COG1349	DNA-binding transcription factor activity
TETH514_RS05515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TETH514_RS05530	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
TETH514_RS05535	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TETH514_RS05540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TETH514_RS05545	COG1940	carbohydrate kinase activity
TETH514_RS05555	COG1653	transport
TETH514_RS05560	COG1175	transmembrane transport
TETH514_RS05565	COG0395	ABC-type sugar transport system, permease component
TETH514_RS05575	COG3250	beta-galactosidase activity
TETH514_RS05580	COG0383	alpha-mannosidase activity
TETH514_RS05595	COG1653	transport
TETH514_RS05600	COG1175	transmembrane transport
TETH514_RS05605	COG0395	ABC-type sugar transport system, permease component
TETH514_RS05615	COG4977	sequence-specific DNA binding
TETH514_RS05615	COG1917	Cupin 2, conserved barrel domain protein
TETH514_RS05625	COG0733	neurotransmitter:sodium symporter activity
TETH514_RS05660	COG0768	penicillin binding
TETH514_RS05670	COG2182	Extracellular solute-binding protein
TETH514_RS05685	COG1621	beta-fructofuranosidase activity
TETH514_RS05690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TETH514_RS05695	COG1609	Transcriptional regulator
TETH514_RS05710	COG2226	methyltransferase
TETH514_RS05725	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TETH514_RS05730	COG0489	protein tyrosine kinase activity
TETH514_RS05740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TETH514_RS05745	COG0446	pyridine nucleotide-disulphide oxidoreductase
TETH514_RS05755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TETH514_RS05760	COG1120	ATPase activity
TETH514_RS05780	COG1918	ferrous iron import across plasma membrane
TETH514_RS05780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TETH514_RS05790	COG1918	ferrous iron import across plasma membrane
TETH514_RS05790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TETH514_RS05800	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TETH514_RS05800	COG2199	diguanylate cyclase activity
TETH514_RS05820	COG5002	protein histidine kinase activity
TETH514_RS05820	COG3447	MASE1 domain protein
TETH514_RS05820	COG5001	Diguanylate cyclase
TETH514_RS05830	COG0586	Pfam SNARE associated Golgi protein
TETH514_RS05835	COG2608	mercury ion transmembrane transporter activity
TETH514_RS05840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TETH514_RS05860	COG0745	RESPONSE REGULATOR receiver
TETH514_RS05865	COG2205	protein histidine kinase activity
TETH514_RS05870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TETH514_RS05875	COG0037	tRNA processing
TETH514_RS05890	COG2217	Heavy metal translocating P-type atpase
TETH514_RS05895	COG2608	mercury ion transmembrane transporter activity
TETH514_RS05940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TETH514_RS05950	COG1752	Esterase of the alpha-beta hydrolase superfamily
TETH514_RS05955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TETH514_RS05980	COG2182	Extracellular solute-binding protein
TETH514_RS05985	COG1175	transmembrane transport
TETH514_RS05990	COG3833	ABC-type maltose transport systems, permease component
TETH514_RS06005	COG1426	Protein conserved in bacteria
TETH514_RS06010	COG0366	Alpha amylase catalytic
TETH514_RS06025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TETH514_RS06030	COG4109	DRTGG domain
TETH514_RS06060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TETH514_RS06070	COG0534	Mate efflux family protein
TETH514_RS06075	COG3273	potassium ion transport
TETH514_RS06075	COG0471	metal ion transport
TETH514_RS06080	COG0517	IMP dehydrogenase activity
TETH514_RS06080	COG1125	glycine betaine transport
TETH514_RS06085	COG1174	glycine betaine transport
TETH514_RS06095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TETH514_RS06105	COG2195	Cleaves the N-terminal amino acid of tripeptides
TETH514_RS06110	COG0778	Nitroreductase
TETH514_RS06120	COG0058	SHG alpha-glucan phosphorylase activity
TETH514_RS06130	COG0646	methionine synthase
TETH514_RS06130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TETH514_RS06135	COG1410	methionine synthase
TETH514_RS06135	COG0646	methionine synthase
TETH514_RS06140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TETH514_RS06145	COG3546	catalase activity
TETH514_RS06155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TETH514_RS06250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TETH514_RS06250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TETH514_RS06295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TETH514_RS06335	COG1802	Transcriptional regulator
TETH514_RS06335	COG4626	Terminase
TETH514_RS06420	COG4824	toxin secretion phage lysis holin
TETH514_RS06455	COG2217	Heavy metal translocating P-type atpase
TETH514_RS06460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TETH514_RS06495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TETH514_RS06500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TETH514_RS06515	COG0564	pseudouridine synthase activity
TETH514_RS06525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TETH514_RS06560	COG1067	ATP-dependent peptidase activity
TETH514_RS06565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TETH514_RS06570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TETH514_RS06575	COG2720	vancomycin resistance protein
TETH514_RS06585	COG0561	phosphatase activity
TETH514_RS06590	COG1254	Belongs to the acylphosphatase family
TETH514_RS06600	COG2390	Transcriptional regulator
TETH514_RS06610	COG0126	phosphoglycerate kinase activity
TETH514_RS06620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TETH514_RS06630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TETH514_RS06635	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TETH514_RS06640	COG0358	DNA primase activity
TETH514_RS06645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TETH514_RS06665	COG2384	SAM-dependent methyltransferase
TETH514_RS06670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TETH514_RS06680	COG1482	cell wall glycoprotein biosynthetic process
TETH514_RS06690	COG0475	glutathione-regulated potassium exporter activity
TETH514_RS06705	COG0701	Predicted permease
TETH514_RS06715	COG3344	reverse transcriptase
TETH514_RS06740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TETH514_RS06745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TETH514_RS06750	COG0537	adenosine 5'-monophosphoramidase activity
TETH514_RS06780	COG1702	phosphate starvation-inducible protein PhoH
TETH514_RS06785	COG1480	7TM receptor with intracellular HD hydrolase
TETH514_RS06795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TETH514_RS06820	COG0423	glycine-tRNA ligase activity
TETH514_RS06825	COG0517	IMP dehydrogenase activity
TETH514_RS06835	COG0574	Belongs to the PEP-utilizing enzyme family
TETH514_RS06835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TETH514_RS06845	COG0557	exoribonuclease II activity
TETH514_RS06865	COG1132	(ABC) transporter
TETH514_RS06915	COG1132	(ABC) transporter
TETH514_RS06940	COG1132	(ABC) transporter
TETH514_RS06970	COG0693	protein deglycase activity
TETH514_RS06980	COG2414	aldehyde ferredoxin oxidoreductase
TETH514_RS06995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TETH514_RS07020	COG0521	Mo-molybdopterin cofactor biosynthetic process
TETH514_RS07025	COG0303	'Molybdopterin
TETH514_RS07030	COG1910	domain protein
TETH514_RS07075	COG2267	carboxylic ester hydrolase activity
TETH514_RS07095	COG0584	glycerophosphoryl diester phosphodiesterase
TETH514_RS07105	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TETH514_RS07125	COG3069	C4-dicarboxylate transmembrane transporter activity
TETH514_RS07135	COG0426	domain, Protein
TETH514_RS07140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TETH514_RS07150	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TETH514_RS07155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TETH514_RS07160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TETH514_RS07175	COG1760	l-serine dehydratase
TETH514_RS07180	COG1164	Oligoendopeptidase f
TETH514_RS07190	COG0077	Prephenate dehydratase
TETH514_RS07190	COG1605	Chorismate mutase
TETH514_RS07195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TETH514_RS07200	COG0287	Prephenate dehydrogenase
TETH514_RS07215	COG2119	membrane
TETH514_RS07235	COG0785	Cytochrome C biogenesis protein
TETH514_RS07240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TETH514_RS07245	COG3118	belongs to the thioredoxin family
TETH514_RS07250	COG1982	Orn Lys Arg decarboxylase major
TETH514_RS07270	COG2385	sporulation resulting in formation of a cellular spore
TETH514_RS07275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TETH514_RS07290	COG1739	Uncharacterized protein family UPF0029
TETH514_RS07310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TETH514_RS07320	COG0835	chemotaxis
TETH514_RS07330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TETH514_RS07375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
TETH514_RS07380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TETH514_RS07385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TETH514_RS07385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TETH514_RS07395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TETH514_RS07395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TETH514_RS07415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TETH514_RS07435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TETH514_RS07440	COG1937	Protein conserved in bacteria
TETH514_RS07445	COG3118	belongs to the thioredoxin family
TETH514_RS07450	COG3118	belongs to the thioredoxin family
TETH514_RS07455	COG3804	dihydrodipicolinate reductase
TETH514_RS07465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TETH514_RS07475	COG5012	cobalamin binding
TETH514_RS07485	COG3457	Alanine racemase
TETH514_RS07495	COG1959	2 iron, 2 sulfur cluster binding
TETH514_RS07505	COG0628	permease
TETH514_RS07515	COG4472	Bacterial protein of unknown function (DUF965)
TETH514_RS07525	COG3906	Belongs to the UPF0473 family
TETH514_RS07530	COG0735	belongs to the Fur family
TETH514_RS07535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TETH514_RS07540	COG3679	Belongs to the UPF0342 family
TETH514_RS07545	COG4708	membrane
TETH514_RS07550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TETH514_RS07555	COG4122	O-methyltransferase activity
TETH514_RS07560	COG0826	peptidase U32
TETH514_RS07565	COG0768	penicillin binding
TETH514_RS07575	COG0546	phosphoglycolate phosphatase activity
TETH514_RS07580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TETH514_RS07585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TETH514_RS07595	COG1459	type II secretion system
TETH514_RS07605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TETH514_RS07675	COG0006	proline dipeptidase activity
TETH514_RS07690	COG3854	ATPases associated with a variety of cellular activities
TETH514_RS07730	COG1302	Protein conserved in bacteria
TETH514_RS07740	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TETH514_RS07755	COG0142	geranyltranstransferase activity
TETH514_RS07765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TETH514_RS07770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
TETH514_RS07785	COG0497	DNA recombination
TETH514_RS07790	COG0750	zinc metalloprotease
TETH514_RS07830	COG1379	DNA repair
TETH514_RS07835	COG1300	Membrane
TETH514_RS07840	COG4974	Belongs to the 'phage' integrase family
TETH514_RS07845	COG1686	Belongs to the peptidase S11 family
TETH514_RS07850	COG1366	Belongs to the anti-sigma-factor antagonist family
TETH514_RS07865	COG3360	Dodecin
TETH514_RS07885	COG0517	IMP dehydrogenase activity
TETH514_RS07885	COG0617	tRNA 3'-terminal CCA addition
TETH514_RS07885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TETH514_RS07890	COG1994	Peptidase M50
TETH514_RS07900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TETH514_RS07905	COG4086	secreted protein
TETH514_RS07915	COG3874	Sporulation protein YtfJ
TETH514_RS07920	COG1301	dicarboxylic acid transport
TETH514_RS07925	COG1030	water channel activity
TETH514_RS07940	COG1686	Belongs to the peptidase S11 family
TETH514_RS07950	COG0445	tRNA wobble uridine modification
TETH514_RS07955	COG1187	pseudouridine synthase activity
TETH514_RS07970	COG0010	Belongs to the arginase family
TETH514_RS07980	COG1388	LysM domain
TETH514_RS07980	COG1705	Flagellar rod assembly protein muramidase FlgJ
TETH514_RS08000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TETH514_RS08000	COG0674	pyruvate-flavodoxin oxidoreductase activity
TETH514_RS08005	COG1013	pyruvate-flavodoxin oxidoreductase activity
TETH514_RS08030	COG1914	H( )-stimulated, divalent metal cation uptake system
TETH514_RS08035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TETH514_RS08040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TETH514_RS08045	COG1984	allophanate hydrolase subunit 2
TETH514_RS08060	COG0406	alpha-ribazole phosphatase activity
TETH514_RS08065	COG2081	HI0933 family
TETH514_RS08080	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TETH514_RS08105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TETH514_RS08115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TETH514_RS08135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TETH514_RS08145	COG4974	Belongs to the 'phage' integrase family
TETH514_RS08150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
TETH514_RS08155	COG0464	growth
TETH514_RS08160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TETH514_RS08170	COG0613	PHP domain protein
TETH514_RS08175	COG2359	stage V sporulation protein S
TETH514_RS08180	COG1692	metallophosphoesterase
TETH514_RS08190	COG2137	regulation of response to DNA damage stimulus
TETH514_RS08195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TETH514_RS08205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TETH514_RS08215	COG1674	ftsk spoiiie
TETH514_RS08225	COG0740	serine-type endopeptidase activity
TETH514_RS08230	COG0527	aspartate kinase activity
TETH514_RS08245	COG0612	Peptidase, M16
TETH514_RS08250	COG0726	polysaccharide deacetylase
TETH514_RS08265	COG0196	riboflavin kinase activity
TETH514_RS08270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TETH514_RS08280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TETH514_RS08295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
TETH514_RS08300	COG0195	Participates in both transcription termination and antitermination
TETH514_RS08310	COG2176	DNA-directed DNA polymerase activity
TETH514_RS08320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TETH514_RS08325	COG0750	zinc metalloprotease
TETH514_RS08335	COG4589	Belongs to the CDS family
TETH514_RS08340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TETH514_RS08355	COG0528	UMP kinase activity
TETH514_RS08380	COG1191	sigma factor activity
TETH514_RS08385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TETH514_RS08390	COG1776	CheC inhibitor of MCP methylation
TETH514_RS08395	COG0835	chemotaxis
TETH514_RS08400	COG2198	Histidine kinase
TETH514_RS08400	COG0643	Histidine kinase
TETH514_RS08405	COG2201	protein-glutamate methylesterase activity
TETH514_RS08420	COG1419	protein localization to endoplasmic reticulum
TETH514_RS08425	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TETH514_RS08430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TETH514_RS08435	COG1684	flagellar biosynthetic protein fliR
TETH514_RS08440	COG1987	bacterial-type flagellum assembly
TETH514_RS08445	COG1338	Plays a role in the flagellum-specific transport system
TETH514_RS08455	COG2201	protein-glutamate methylesterase activity
TETH514_RS08460	COG1776	CheC inhibitor of MCP methylation
TETH514_RS08460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TETH514_RS08465	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TETH514_RS08475	COG1582	Flagellar protein (FlbD)
TETH514_RS08490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TETH514_RS08510	COG1157	protein secretion by the type III secretion system
TETH514_RS08520	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TETH514_RS08525	COG1766	The M ring may be actively involved in energy transduction
TETH514_RS08530	COG1677	Flagellar hook-basal body complex protein FliE
TETH514_RS08540	COG1815	bacterial-type flagellum-dependent cell motility
TETH514_RS08560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TETH514_RS08565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TETH514_RS08565	COG0758	DNA mediated transformation
TETH514_RS08570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TETH514_RS08575	COG0792	nuclease activity
TETH514_RS08580	COG0180	Tryptophanyl-tRNA synthetase
TETH514_RS08585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TETH514_RS08590	COG0606	chelatase, subunit chli
TETH514_RS08605	COG0336	Belongs to the RNA methyltransferase TrmD family
TETH514_RS08615	COG1837	Belongs to the UPF0109 family
TETH514_RS08625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TETH514_RS08635	COG0552	protein localization to endoplasmic reticulum
TETH514_RS08650	COG2359	stage V sporulation protein S
TETH514_RS08660	COG0571	ribonuclease III activity
TETH514_RS08665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TETH514_RS08675	COG1028	Short-chain dehydrogenase reductase Sdr
TETH514_RS08680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TETH514_RS08685	COG2070	2-Nitropropane dioxygenase
TETH514_RS08690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TETH514_RS08705	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TETH514_RS08710	COG1399	metal-binding, possibly nucleic acid-binding protein
TETH514_RS08715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TETH514_RS08720	COG0280	phosphate acetyltransferase
TETH514_RS08730	COG3314	Sporulation integral membrane protein YlbJ
TETH514_RS08745	COG0742	ribosomal rna small subunit methyltransferase
TETH514_RS08760	COG1307	EDD domain protein, DegV family
TETH514_RS08765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TETH514_RS08770	COG1461	Dihydroxyacetone kinase
TETH514_RS08775	COG1302	Protein conserved in bacteria
TETH514_RS08795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TETH514_RS08800	COG1162	GTPase activity
TETH514_RS08805	COG0515	serine threonine protein kinase
TETH514_RS08805	COG2815	serine threonine protein kinase
TETH514_RS08810	COG0631	protein serine/threonine phosphatase activity
TETH514_RS08820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TETH514_RS08820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TETH514_RS08825	COG2738	Putative neutral zinc metallopeptidase
TETH514_RS08835	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TETH514_RS08850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TETH514_RS08855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TETH514_RS08865	COG0194	GDP metabolic process
TETH514_RS08875	COG1561	YicC-like family, N-terminal region
TETH514_RS08880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TETH514_RS08885	COG2814	Major facilitator Superfamily
TETH514_RS08905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TETH514_RS08910	COG2011	ABC-type metal ion transport system permease component
TETH514_RS08940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TETH514_RS08945	COG1573	uracil-dna glycosylase
TETH514_RS08960	COG0037	tRNA processing
TETH514_RS08965	COG0366	Alpha amylase catalytic
TETH514_RS08965	COG3103	Sh3 type 3 domain protein
TETH514_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
TETH514_RS08980	COG1181	Belongs to the D-alanine--D-alanine ligase family
TETH514_RS08995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TETH514_RS09000	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TETH514_RS09005	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TETH514_RS09015	COG4608	Belongs to the ABC transporter superfamily
TETH514_RS09020	COG0444	Belongs to the ABC transporter superfamily
TETH514_RS09030	COG0601	transmembrane transport
TETH514_RS09035	COG4166	transmembrane transport
TETH514_RS09070	COG1191	sigma factor activity
TETH514_RS09080	COG1187	pseudouridine synthase activity
TETH514_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
TETH514_RS09115	COG0037	tRNA processing
TETH514_RS09140	COG0543	2 iron, 2 sulfur cluster binding
TETH514_RS09155	COG0540	Belongs to the ATCase OTCase family
TETH514_RS09170	COG0564	pseudouridine synthase activity
TETH514_RS09175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TETH514_RS09215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TETH514_RS09220	COG1715	Restriction endonuclease
TETH514_RS09225	COG1715	Restriction endonuclease
TETH514_RS09285	COG1970	mechanosensitive ion channel activity
TETH514_RS09300	COG0778	Nitroreductase
TETH514_RS09305	COG1595	DNA-templated transcription, initiation
TETH514_RS09320	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TETH514_RS09330	COG0346	lactoylglutathione lyase activity
TETH514_RS09335	COG1703	isobutyryl-CoA mutase activity
TETH514_RS09340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TETH514_RS09340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TETH514_RS09345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TETH514_RS09345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TETH514_RS09375	COG0626	cystathionine gamma-synthase activity
TETH514_RS09380	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TETH514_RS09385	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TETH514_RS09415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TETH514_RS09415	COG0512	Glutamine amidotransferase of anthranilate synthase
TETH514_RS09460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TETH514_RS09470	COG1122	ATPase activity
TETH514_RS09485	COG2188	Transcriptional regulator
TETH514_RS09510	COG3599	regulation of cell shape
TETH514_RS09515	COG2302	S4 RNA-binding domain
TETH514_RS09530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TETH514_RS09545	COG2610	gluconate transmembrane transporter activity
TETH514_RS09550	COG1929	Belongs to the glycerate kinase type-1 family
TETH514_RS09555	COG3835	regulator
TETH514_RS09575	COG0632	four-way junction helicase activity
TETH514_RS09600	COG1461	Dihydroxyacetone kinase
TETH514_RS09610	COG2376	Dihydroxyacetone kinase
TETH514_RS09635	COG1012	belongs to the aldehyde dehydrogenase family
TETH514_RS09650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TETH514_RS09660	COG0613	PHP domain protein
TETH514_RS09670	COG0698	ribose 5-phosphate isomerase
TETH514_RS09675	COG3958	Transketolase
TETH514_RS09680	COG3959	Transketolase, thiamine diphosphate binding domain
TETH514_RS09685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TETH514_RS09715	COG1120	ATPase activity
TETH514_RS09720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TETH514_RS09725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TETH514_RS09730	COG1454	alcohol dehydrogenase
TETH514_RS09735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TETH514_RS09745	COG4810	utilization protein
TETH514_RS09750	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
TETH514_RS09755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TETH514_RS09765	COG1012	belongs to the aldehyde dehydrogenase family
TETH514_RS09775	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
TETH514_RS09790	COG4869	propanediol catabolic process
TETH514_RS09835	COG1971	Probably functions as a manganese efflux pump
TETH514_RS09845	COG2197	response regulator
TETH514_RS09850	COG2972	Histidine kinase
TETH514_RS09875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TETH514_RS09880	COG3829	transcription factor binding
TETH514_RS09895	COG2814	Major facilitator Superfamily
TETH514_RS09900	COG1131	(ABC) transporter
TETH514_RS09910	COG0653	protein targeting
TETH514_RS09915	COG0531	amino acid
TETH514_RS09925	COG0745	RESPONSE REGULATOR receiver
TETH514_RS09930	COG5001	Diguanylate cyclase
TETH514_RS09930	COG3447	MASE1 domain protein
TETH514_RS09930	COG5002	protein histidine kinase activity
TETH514_RS09940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TETH514_RS09995	COG0704	Plays a role in the regulation of phosphate uptake
TETH514_RS10000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TETH514_RS10005	COG0581	inorganic phosphate transmembrane transporter activity
TETH514_RS10010	COG0573	inorganic phosphate transmembrane transporter activity
TETH514_RS10015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TETH514_RS10020	COG5002	protein histidine kinase activity
TETH514_RS10025	COG0745	RESPONSE REGULATOR receiver
TETH514_RS10035	COG1873	PFAM PRC-barrel domain
TETH514_RS10040	COG1191	sigma factor activity
TETH514_RS10045	COG1191	sigma factor activity
TETH514_RS10055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TETH514_RS10060	COG0849	cell division
TETH514_RS10065	COG3856	small basic protein
TETH514_RS10080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TETH514_RS10090	COG0772	Belongs to the SEDS family
TETH514_RS10105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TETH514_RS10110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TETH514_RS10115	COG0768	penicillin binding
TETH514_RS10120	COG3116	cell division
TETH514_RS10135	COG0612	Peptidase, M16
TETH514_RS10140	COG0612	Peptidase, M16
TETH514_RS10150	COG0012	GTP binding
TETH514_RS10175	COG3344	reverse transcriptase
TETH514_RS10190	COG0508	dehydrogenase complex catalyzes the overall conversion of
TETH514_RS10195	COG3199	ATP-NAD kinase
TETH514_RS10200	COG0022	dehydrogenase e1 component
TETH514_RS10205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TETH514_RS10210	COG0459	protein refolding
TETH514_RS10220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TETH514_RS10230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TETH514_RS10245	COG1362	aminopeptidase activity
TETH514_RS10250	COG2197	response regulator
TETH514_RS10270	COG1683	Conserved Protein
TETH514_RS10275	COG1193	negative regulation of DNA recombination
TETH514_RS10280	COG0826	peptidase U32
TETH514_RS10290	COG0072	phenylalanine-tRNA ligase activity
TETH514_RS10290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TETH514_RS10295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TETH514_RS10300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TETH514_RS10315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TETH514_RS10330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TETH514_RS10335	COG4399	Belongs to the UPF0754 family
TETH514_RS10350	COG0745	RESPONSE REGULATOR receiver
TETH514_RS10355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TETH514_RS10395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TETH514_RS10405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TETH514_RS10410	COG1956	GAF domain-containing protein
TETH514_RS10425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TETH514_RS10435	COG0701	Predicted permease
TETH514_RS10450	COG3830	Belongs to the UPF0237 family
TETH514_RS10455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TETH514_RS10465	COG0484	heat shock protein binding
TETH514_RS10475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TETH514_RS10485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TETH514_RS10510	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
TETH514_RS10520	COG0268	Binds directly to 16S ribosomal RNA
TETH514_RS10535	COG1234	tRNA 3'-trailer cleavage
TETH514_RS10545	COG4720	Psort location CytoplasmicMembrane, score
TETH514_RS10560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TETH514_RS10585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TETH514_RS10590	COG1596	polysaccharide export
TETH514_RS10590	COG1555	photosystem II stabilization
TETH514_RS10595	COG1686	Belongs to the peptidase S11 family
TETH514_RS10600	COG0367	asparagine synthase
TETH514_RS10620	COG0799	negative regulation of ribosome biogenesis
TETH514_RS10625	COG1713	HD superfamily hydrolase involved in NAD metabolism
TETH514_RS10665	COG4708	membrane
TETH514_RS10675	COG1530	ribonuclease E activity
TETH514_RS10690	COG0517	IMP dehydrogenase activity
TETH514_RS10690	COG1994	Peptidase M50
TETH514_RS10695	COG0739	heme binding
TETH514_RS10705	COG0772	Belongs to the SEDS family
TETH514_RS10715	COG2894	cell division
TETH514_RS10725	COG0768	penicillin binding
TETH514_RS10740	COG1077	Cell shape determining protein MreB Mrl
TETH514_RS10745	COG2003	Belongs to the UPF0758 family
TETH514_RS10775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TETH514_RS10775	COG4191	Histidine kinase
TETH514_RS10795	COG2878	Part of a membrane complex involved in electron transport
TETH514_RS10815	COG0741	lytic transglycosylase activity
TETH514_RS10820	COG1217	gtp-binding protein TYPA
TETH514_RS10825	COG0791	NLP P60 protein
TETH514_RS10845	COG0741	lytic transglycosylase activity
TETH514_RS10850	COG0237	dephospho-CoA kinase activity
TETH514_RS10855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TETH514_RS10855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TETH514_RS10880	COG4475	Protein of unknown function (DUF436)
TETH514_RS10920	COG2986	histidine ammonia-lyase
TETH514_RS10935	COG0739	heme binding
TETH514_RS10945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TETH514_RS10950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TETH514_RS10970	COG1132	(ABC) transporter
TETH514_RS10975	COG1132	(ABC) transporter
TETH514_RS10985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TETH514_RS10995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TETH514_RS11005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TETH514_RS11020	COG3773	Cell wall hydrolase
TETH514_RS11020	COG3409	Peptidoglycan-binding domain 1 protein
TETH514_RS11025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TETH514_RS11025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TETH514_RS11030	COG1404	Belongs to the peptidase S8 family
TETH514_RS11045	COG0395	ABC-type sugar transport system, permease component
TETH514_RS11060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TETH514_RS11065	COG0395	ABC-type sugar transport system, permease component
TETH514_RS11070	COG1175	transmembrane transport
TETH514_RS11085	COG1609	Transcriptional regulator
TETH514_RS11090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TETH514_RS11120	COG0285	dihydrofolate synthase activity
TETH514_RS11130	COG0525	valine-tRNA ligase activity
TETH514_RS11155	COG0745	RESPONSE REGULATOR receiver
TETH514_RS11160	COG5002	protein histidine kinase activity
TETH514_RS11165	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TETH514_RS11170	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TETH514_RS11175	COG1691	(AIR) carboxylase
TETH514_RS11180	COG1606	tRNA processing
TETH514_RS11185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TETH514_RS11200	COG3344	reverse transcriptase
TETH514_RS11215	COG2814	Major facilitator Superfamily
TETH514_RS11230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TETH514_RS11240	COG3949	Membrane
TETH514_RS11245	COG1316	TRANSCRIPTIONal
TETH514_RS11255	COG0489	protein tyrosine kinase activity
TETH514_RS11260	COG3944	biosynthesis protein
TETH514_RS11265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TETH514_RS11275	COG0250	Participates in transcription elongation, termination and antitermination
TETH514_RS11330	COG1914	H( )-stimulated, divalent metal cation uptake system
TETH514_RS11340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TETH514_RS11355	COG4989	oxidoreductase activity
TETH514_RS11360	COG0622	Phosphoesterase
TETH514_RS11365	COG1704	LemA family
TETH514_RS11385	COG2161	toxin-antitoxin pair type II binding
TETH514_RS11400	COG1401	restriction endodeoxyribonuclease activity
TETH514_RS11455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TETH514_RS11460	COG0438	transferase activity, transferring glycosyl groups
TETH514_RS11475	COG0438	transferase activity, transferring glycosyl groups
TETH514_RS11485	COG0438	transferase activity, transferring glycosyl groups
TETH514_RS11520	COG2239	Acts as a magnesium transporter
TETH514_RS11525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TETH514_RS11530	COG1116	anion transmembrane transporter activity
TETH514_RS11535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TETH514_RS11540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TETH514_RS11540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TETH514_RS11555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TETH514_RS11580	COG0504	CTP synthase activity
TETH514_RS11590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TETH514_RS11595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TETH514_RS11605	COG0083	homoserine kinase activity
TETH514_RS11610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TETH514_RS11615	COG0460	homoserine dehydrogenase
TETH514_RS11625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TETH514_RS11635	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TETH514_RS11640	COG1518	maintenance of DNA repeat elements
TETH514_RS11650	COG3340	Belongs to the peptidase S51 family
TETH514_RS11695	COG0822	iron-sulfur transferase activity
TETH514_RS11700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TETH514_RS11710	COG0719	Fe-S assembly protein
TETH514_RS11715	COG0396	ATPase activity
TETH514_RS11720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TETH514_RS11740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TETH514_RS11755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TETH514_RS11760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TETH514_RS11770	COG0739	heme binding
TETH514_RS11780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TETH514_RS11785	COG0308	aminopeptidase N
TETH514_RS11800	COG2333	competence protein COMEC
TETH514_RS11800	COG0658	competence protein
TETH514_RS11825	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TETH514_RS11830	COG0840	transmembrane signaling receptor activity
TETH514_RS11840	COG0446	pyridine nucleotide-disulphide oxidoreductase
TETH514_RS11875	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TETH514_RS11880	COG1527	subunit (C
TETH514_RS11890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TETH514_RS11895	COG1269	ATP hydrolysis coupled proton transport
TETH514_RS11995	COG0305	Participates in initiation and elongation during chromosome replication
TETH514_RS12025	COG0629	single-stranded DNA binding
TETH514_RS12035	COG4481	Protein conserved in bacteria
TETH514_RS12040	COG0668	transmembrane transport
TETH514_RS12050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TETH514_RS12050	COG0189	ligase activity
TETH514_RS12055	COG4242	Belongs to the peptidase S51 family
TETH514_RS12060	COG1597	lipid kinase activity
TETH514_RS12070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TETH514_RS12075	COG1475	DNA binding
TETH514_RS12080	COG1192	Involved in chromosome partitioning
TETH514_RS12110	COG1847	R3H domain protein
TETH514_RS12115	COG0706	membrane insertase activity