locus-tag	class	description
GSH73_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GSH73_RS00010	ENOG4105VG0	50S ribosomal protein l34
GSH73_RS00015	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GSH73_RS00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GSH73_RS00025	ENOG4107R4E	Membrane
GSH73_RS00030	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
GSH73_RS00035	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GSH73_RS00040	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GSH73_RS00045	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GSH73_RS00055	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
GSH73_RS00060	ENOG4107QJE	Chromosome Partitioning Protein
GSH73_RS00065	ENOG4105FA0	parb-like partition protein
GSH73_RS00070	ENOG4107QW8	radical SAM domain protein
GSH73_RS00100	ENOG4108ZDA	Sporulation protein YyaC
GSH73_RS00110	ENOG4105D8X	mechanosensitive ion channel
GSH73_RS00115	ENOG4105VDK	protein, conserved in bacteria
GSH73_RS00120	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GSH73_RS00125	ENOG4108UUM	single-stranded DNA-binding protein
GSH73_RS00130	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GSH73_RS00145	ENOG4105BZR	domain protein
GSH73_RS00150	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GSH73_RS00155	ENOG4105CDU	Replicative dna helicase
GSH73_RS00160	ENOG4105IJJ	transcriptional regulator, crp fnr family
GSH73_RS00165	ENOG4105CJW	magnesium transporter
GSH73_RS00170	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GSH73_RS00175	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS00180	ENOG4105BZU	Histidine kinase
GSH73_RS00190	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
GSH73_RS00195	ENOG4107XM3	UPF0442 protein
GSH73_RS00205	ENOG4105DZ0	fad dependent oxidoreductase
GSH73_RS00210	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GSH73_RS00240	ENOG4108N5B	2-phosphosulfolactate phosphatase
GSH73_RS00265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS00270	ENOG4105C0H	protease
GSH73_RS00275	ENOG4106HBX	Transcriptional Regulator AraC Family
GSH73_RS00280	ENOG4105EQR	Transposase IS116 IS110 IS902
GSH73_RS00290	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
GSH73_RS00300	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS00305	ENOG4105DRS	transport system, permease
GSH73_RS00310	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GSH73_RS00330	ENOG4105EQR	Transposase IS116 IS110 IS902
GSH73_RS00335	ENOG4105C6K	Malic enzyme
GSH73_RS00360	ENOG4108MRH	transcriptional regulatory protein
GSH73_RS00425	ENOG4105DQ6	Transposase
GSH73_RS00495	ENOG4105EQR	Transposase IS116 IS110 IS902
GSH73_RS00530	ENOG4108K5P	(LipO)protein
GSH73_RS00540	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS00545	ENOG4105BZU	Histidine kinase
GSH73_RS00565	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSH73_RS00580	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GSH73_RS00585	ENOG4105BZU	Histidine kinase
GSH73_RS00640	ENOG4105CIZ	coA-substrate-specific enzyme activase
GSH73_RS00660	ENOG4105CPC	Aldo Keto reductase
GSH73_RS00670	ENOG4108EKI	Dehydrogenase
GSH73_RS00765	ENOG4105DIW	FeS assembly protein SUFB
GSH73_RS00770	ENOG4105DIW	FeS assembly protein SUFB
GSH73_RS00780	ENOG4107YH3	SUF system FeS assembly protein, NifU family
GSH73_RS00820	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GSH73_RS00825	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GSH73_RS00835	ENOG410834F	Transcriptional regulator
GSH73_RS00845	ENOG4105BZ1	(ABC) transporter
GSH73_RS00850	ENOG4105DQU	oxidoreductase, subunit beta
GSH73_RS00855	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GSH73_RS00860	ENOG4105Q2H	domain protein
GSH73_RS00870	ENOG41090I5	UPF0735 ACT domain-containing protein
GSH73_RS00875	ENOG4105D6E	homoserine dehydrogenase
GSH73_RS00880	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
GSH73_RS00885	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GSH73_RS00890	ENOG4105CN1	protease
GSH73_RS00895	ENOG4105BZW	Glycerate kinase
GSH73_RS00900	ENOG4105C5R	Aminotransferase
GSH73_RS00925	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GSH73_RS00960	ENOG4105F3H	Histidine kinase
GSH73_RS00970	ENOG4105EDW	glycosyl transferase, family 39
GSH73_RS00975	ENOG4105CKK	Glycosyl transferase, family 2
GSH73_RS01010	ENOG4105E98	transcriptional regulator DeoR family
GSH73_RS01015	ENOG4105DE4	1-phosphofructokinase
GSH73_RS01020	ENOG4105DM4	PTS System
GSH73_RS01025	ENOG4105DM4	PTS System
GSH73_RS01040	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS01060	ENOG4105CS2	ec 3.2.1.21
GSH73_RS01070	ENOG4105BZ1	(ABC) transporter
GSH73_RS01075	ENOG4105BZ1	(ABC) transporter
GSH73_RS01080	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS01090	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSH73_RS01095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSH73_RS01105	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSH73_RS01110	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GSH73_RS01125	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GSH73_RS01130	ENOG41082DI	50s ribosomal protein l31
GSH73_RS01135	ENOG4107104	thymidine kinase
GSH73_RS01140	ENOG4105CBJ	Metal-dependent enzyme
GSH73_RS01145	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GSH73_RS01155	ENOG41081FK	Mediates zinc uptake. May also transport other divalent cations (By similarity)
GSH73_RS01160	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSH73_RS01165	ENOG4107WAU	Protein tyrosine phosphatase
GSH73_RS01170	ENOG4108YZG	isomerase
GSH73_RS01175	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GSH73_RS01185	ENOG4105ESV	Glycosyl transferase, family 4
GSH73_RS01190	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GSH73_RS01200	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSH73_RS01220	ENOG4107SC7	Inner membrane transporter yjeM
GSH73_RS01225	ENOG4107QSE	Dipeptidase
GSH73_RS01275	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
GSH73_RS01290	ENOG4105CGA	flagellar basal-body rod protein FlgG
GSH73_RS01300	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GSH73_RS01305	ENOG4105CJR	Integral membrane protein (MviN
GSH73_RS01315	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GSH73_RS01320	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
GSH73_RS01325	ENOG4107TVC	Glycosyl transferase, family 2
GSH73_RS01335	ENOG4107QW4	alcohol dehydrogenase
GSH73_RS01340	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
GSH73_RS01370	ENOG4105CMG	Carbohydrate kinase
GSH73_RS01385	ENOG4108HWW	ABC transporter
GSH73_RS01395	ENOG4105CY0	Metallo-Beta-Lactamase
GSH73_RS01400	ENOG4108M60	Transcriptional regulator
GSH73_RS01410	ENOG4105D7K	pfkb domain protein
GSH73_RS01415	ENOG4106ETB	IIa component
GSH73_RS01420	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GSH73_RS01435	ENOG4108HHA	Transketolase
GSH73_RS01475	ENOG4107RGD	Major Facilitator superfamily
GSH73_RS01480	ENOG4108JJB	ABC transporter
GSH73_RS01490	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
GSH73_RS01495	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
GSH73_RS01500	ENOG4105MRR	Transcriptional regulator (By similarity)
GSH73_RS01510	ENOG4105CIG	ABC transporter
GSH73_RS01535	ENOG4105C59	p-type ATPase
GSH73_RS01545	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GSH73_RS01550	ENOG4105UQX	Mate efflux family protein
GSH73_RS01590	ENOG4105CY0	Metallo-Beta-Lactamase
GSH73_RS01595	ENOG4105QUH	Domain of unknown function (DUF2088)
GSH73_RS01615	ENOG4105E98	transcriptional regulator DeoR family
GSH73_RS01630	ENOG4105YCI	dehydratase medium subunit
GSH73_RS01635	ENOG4108ZFT	Dehydratase small subunit
GSH73_RS01640	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
GSH73_RS01660	ENOG4108EKI	Dehydrogenase
GSH73_RS01665	ENOG4105CPQ	Dehydrogenase
GSH73_RS01670	ENOG4108X49	Ethanolamine utilization protein EutK
GSH73_RS01675	ENOG4105KNY	Microcompartments protein
GSH73_RS01680	ENOG4105KNY	Microcompartments protein
GSH73_RS01685	ENOG4105KNY	Microcompartments protein
GSH73_RS01690	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
GSH73_RS01700	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
GSH73_RS01710	ENOG4105DKG	l-rhamnose isomerase
GSH73_RS01715	ENOG4105DET	Rhamnulokinase
GSH73_RS01720	ENOG4105EQD	regulatoR
GSH73_RS01745	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS01750	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GSH73_RS01785	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
GSH73_RS01790	ENOG4107QPH	glycogen) synthase
GSH73_RS01795	ENOG4107ZTW	SNARE associated Golgi
GSH73_RS01810	ENOG4105VTR	Integrase
GSH73_RS01825	ENOG4105C0D	helicase
GSH73_RS01865	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
GSH73_RS01870	ENOG4105BZ8	glutamate synthase
GSH73_RS01895	ENOG4105D2H	Uronic isomerase
GSH73_RS01900	ENOG4107KJX	Transcriptional regulator
GSH73_RS01905	ENOG4105F5H	Glycosyl Hydrolase Family 88
GSH73_RS01915	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS01920	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GSH73_RS01930	ENOG4107QZW	Altronate oxidoreductase
GSH73_RS01935	ENOG4105CTX	dehydratase
GSH73_RS01945	ENOG4105UQX	Mate efflux family protein
GSH73_RS01965	ENOG4108JQ1	Dehydrogenase
GSH73_RS01970	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GSH73_RS01975	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GSH73_RS01980	ENOG4105DEI	Mannitol dehydrogenase
GSH73_RS02000	ENOG4105DRS	transport system, permease
GSH73_RS02005	ENOG4105CNT	hydrolase family 2
GSH73_RS02020	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS02025	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GSH73_RS02030	ENOG4105CHR	reductase
GSH73_RS02035	ENOG4105NBU	tryptophan transport protein
GSH73_RS02045	ENOG4105C2F	Histidine kinase
GSH73_RS02050	ENOG4105EQD	regulatoR
GSH73_RS02055	ENOG4105DFW	ABC transporter
GSH73_RS02060	ENOG4105DFW	ABC transporter
GSH73_RS02070	ENOG4108HWW	ABC transporter
GSH73_RS02075	ENOG4105CHM	Aminotransferase
GSH73_RS02085	ENOG4105YVF	chew protein
GSH73_RS02090	ENOG4105CBS	Chea signal transduction histidine kinase
GSH73_RS02095	ENOG4105C8Q	Methyl-accepting chemotaxis
GSH73_RS02100	ENOG4105BZU	Histidine kinase
GSH73_RS02105	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GSH73_RS02130	ENOG4105C8T	Leucyl-tRNA synthetase
GSH73_RS02135	ENOG41089WN	small, acid-soluble spore protein tlp
GSH73_RS02150	ENOG4107GRR	phosphate transport regulator
GSH73_RS02155	ENOG4105E5D	amino acid
GSH73_RS02160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSH73_RS02170	ENOG4105CK1	PTS System
GSH73_RS02185	ENOG4105VCP	PTS System
GSH73_RS02190	ENOG4105F8D	glycoside hydrolase family 4
GSH73_RS02195	ENOG4106KNT	transcriptional regulator
GSH73_RS02200	ENOG4105C5Y	PTS System
GSH73_RS02220	ENOG4105CGH	5'-nucleotidase
GSH73_RS02225	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GSH73_RS02295	ENOG4105FDK	ABC transporter
GSH73_RS02300	ENOG4105DSE	periplasmic solute binding protein
GSH73_RS02305	ENOG4105I3K	Ferric uptake regulator, Fur family
GSH73_RS02310	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GSH73_RS02320	ENOG4105CE1	Ferrous iron transport protein b
GSH73_RS02330	ENOG4105CHM	Aminotransferase
GSH73_RS02335	ENOG4108ZB6	transcriptional regulator AsnC family
GSH73_RS02345	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSH73_RS02350	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GSH73_RS02355	ENOG4105CUB	amino acid
GSH73_RS02370	ENOG4105DNE	Transposase
GSH73_RS02385	ENOG4105DNE	Transposase
GSH73_RS02410	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GSH73_RS02415	ENOG4105EHG	Permease protein
GSH73_RS02420	ENOG4105E0A	ABC, transporter
GSH73_RS02425	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GSH73_RS02450	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GSH73_RS02455	ENOG4108YZT	Adenosylcobinamide kinase
GSH73_RS02460	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GSH73_RS02485	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GSH73_RS02530	ENOG4105CCS	Glutamate formiminotransferase
GSH73_RS02535	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
GSH73_RS02540	ENOG4105DIH	basic membrane
GSH73_RS02545	ENOG4108JQ9	ABC transporter
GSH73_RS02550	ENOG4105UIB	(ABC) transporter
GSH73_RS02560	ENOG4105FDP	GntR family transcriptional regulator
GSH73_RS02570	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GSH73_RS02580	ENOG4105C8Q	Methyl-accepting chemotaxis
GSH73_RS02605	ENOG4107SDT	Homocitrate synthase
GSH73_RS02610	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GSH73_RS02620	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GSH73_RS02630	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GSH73_RS02640	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GSH73_RS02675	ENOG4108QG2	Membrane
GSH73_RS02680	ENOG410667J	hydrolase
GSH73_RS02685	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS02690	ENOG4105CE4	GlcNAc 6-P deacetylase
GSH73_RS02695	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS02700	ENOG4105BZU	Histidine kinase
GSH73_RS02710	ENOG4108ZDA	Sporulation protein YyaC
GSH73_RS02745	ENOG4108RAC	Rubrerythrin
GSH73_RS02750	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GSH73_RS02755	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GSH73_RS02765	ENOG4105C7H	Helicase, RecD TraA family
GSH73_RS02770	ENOG4105MJ2	Competence protein
GSH73_RS02790	ENOG4105E1Q	flagellar hook-associated protein
GSH73_RS02795	ENOG4105DTJ	flagellar hook-associated protein
GSH73_RS02805	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
GSH73_RS02810	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GSH73_RS02815	ENOG4105I03	Flagellin
GSH73_RS02825	ENOG41090QV	Protein of unknown function DUF115
GSH73_RS02835	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GSH73_RS02840	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
GSH73_RS02845	ENOG4105D2T	synthase
GSH73_RS02850	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
GSH73_RS02890	ENOG4107RT6	flagellar hook-associated
GSH73_RS02895	ENOG4105MQ3	flagellar protein FliS
GSH73_RS02910	ENOG4108HW3	(ABC) transporter
GSH73_RS02915	ENOG4105E5Q	amino acid AbC transporter
GSH73_RS02920	ENOG4105CDA	abc transporter atp-binding protein
GSH73_RS02935	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GSH73_RS02945	ENOG4108Z3G	3H domain protein
GSH73_RS02955	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
GSH73_RS02960	ENOG41081F0	Precorrin-8x methylmutase
GSH73_RS02970	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
GSH73_RS02975	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
GSH73_RS02980	ENOG4105DVK	Precorrin-2 c20-methyltransferase
GSH73_RS02985	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
GSH73_RS02990	ENOG4108P62	biosynthesis protein (CbiG)
GSH73_RS02995	ENOG4105E4R	Precorrin-3B C17-methyltransferase
GSH73_RS03005	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
GSH73_RS03015	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
GSH73_RS03020	ENOG4108JJB	ABC transporter
GSH73_RS03025	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GSH73_RS03030	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GSH73_RS03040	ENOG4107S1Q	Phosphatase
GSH73_RS03055	ENOG4105DBV	ornithine carbamoyltransferase
GSH73_RS03070	ENOG4105K8N	protein family UPF0079, ATPase
GSH73_RS03075	ENOG41072GX	Peptidase M22 Glycoprotease
GSH73_RS03080	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GSH73_RS03085	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GSH73_RS03095	ENOG4105C5H	ABC transporter
GSH73_RS03100	ENOG4107R0U	MotA TolQ exbB proton channel
GSH73_RS03105	ENOG4105ER2	Ompa motb domain protein
GSH73_RS03115	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GSH73_RS03120	ENOG4108VAC	response regulator
GSH73_RS03145	ENOG4108UQV	Membrane
GSH73_RS03155	ENOG4108IV0	ABC, transporter
GSH73_RS03160	ENOG4105C0Z	ABC transporter
GSH73_RS03165	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GSH73_RS03170	ENOG4105C32	Amino acid ABC transporter (Permease)
GSH73_RS03185	ENOG4105C7J	ABC transporter, permease
GSH73_RS03190	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GSH73_RS03200	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GSH73_RS03225	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GSH73_RS03230	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GSH73_RS03235	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GSH73_RS03250	ENOG4105C7N	Xanthine uracil vitamin C permease
GSH73_RS03255	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GSH73_RS03260	ENOG4105C8V	SAICAR synthetase
GSH73_RS03270	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GSH73_RS03275	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GSH73_RS03280	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GSH73_RS03285	ENOG4107QNG	Phosphoribosylglycinamide synthetase
GSH73_RS03290	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GSH73_RS03295	ENOG4105CH2	amidohydrolase
GSH73_RS03305	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GSH73_RS03315	ENOG4105D01	(LipO)protein
GSH73_RS03320	ENOG4108UMI	ABC transporter, permease
GSH73_RS03325	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GSH73_RS03330	ENOG4105ETD	TRANSCRIPTIONal
GSH73_RS03345	ENOG4105CK1	PTS System
GSH73_RS03350	ENOG4105VCP	PTS System
GSH73_RS03355	ENOG4105KGF	protein, YerC YecD
GSH73_RS03370	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GSH73_RS03380	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GSH73_RS03385	ENOG4108J59	Extracellular solute-binding protein, family 5
GSH73_RS03390	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS03395	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS03405	ENOG4108JQ7	(ABC) transporter
GSH73_RS03410	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSH73_RS03415	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GSH73_RS03470	ENOG4105BZ1	(ABC) transporter
GSH73_RS03475	ENOG4105EJ9	Membrane
GSH73_RS03495	ENOG4107TVC	Glycosyl transferase, family 2
GSH73_RS03510	ENOG4105ECB	domain protein
GSH73_RS03515	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GSH73_RS03525	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GSH73_RS03535	ENOG4108TVJ	Nitroreductase
GSH73_RS03545	ENOG4105CZ9	Domain of unknown function (DU1801)
GSH73_RS03565	ENOG4105CZV	ABC transporter
GSH73_RS03570	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GSH73_RS03580	ENOG4105C4R	Atp-dependent dna helicase
GSH73_RS03595	ENOG4105EMS	pseudouridine synthase
GSH73_RS03675	ENOG4105KY8	Rubrerythrin
GSH73_RS03680	ENOG4105C5I	Dehydrogenase
GSH73_RS03685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSH73_RS03690	ENOG4108EQA	pts system
GSH73_RS03700	ENOG4105F3R	pts system mannose fructose sorbose family iid
GSH73_RS03705	ENOG4108IQ3	PTS system
GSH73_RS03715	ENOG4105C22	threonyL-tRNA synthetase
GSH73_RS03735	ENOG410688J	Ferredoxin
GSH73_RS03745	ENOG4105DAN	ATP-dependent protease
GSH73_RS03750	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GSH73_RS03760	ENOG41073R8	VanW family
GSH73_RS03765	ENOG4105G5W	regulator Fur family
GSH73_RS03770	ENOG410667J	hydrolase
GSH73_RS03775	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GSH73_RS03780	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS03795	ENOG4105BZA	Phosphoglycerate kinase
GSH73_RS03800	ENOG4105CP7	Triose-phosphate isomerase
GSH73_RS03805	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GSH73_RS03810	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GSH73_RS03820	ENOG4105VYW	UPF0251 protein
GSH73_RS03825	ENOG4105XZU	Preprotein translocase, subunit SecG
GSH73_RS03830	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GSH73_RS03835	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GSH73_RS03840	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS03860	ENOG4105EGD	dinuclear metal center protein, YbgI family
GSH73_RS03870	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GSH73_RS03875	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GSH73_RS03880	ENOG4105DG6	mannose-6-phosphate isomerase
GSH73_RS03920	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GSH73_RS03925	ENOG4108ZGC	gaf domain protein
GSH73_RS03930	ENOG4108V0P	LemA family
GSH73_RS03940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GSH73_RS03945	ENOG41083MR	nifu domain-containing protein
GSH73_RS03960	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GSH73_RS03965	ENOG4105VEQ	Cold shock protein
GSH73_RS03995	ENOG4105VTR	Integrase
GSH73_RS04010	ENOG4108IMY	Transcriptional regulator
GSH73_RS04220	ENOG4107YXZ	hydrolase, family 25
GSH73_RS04240	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GSH73_RS04280	ENOG4105XXY	Thioredoxin
GSH73_RS04285	ENOG4105CJR	Integral membrane protein (MviN
GSH73_RS04300	ENOG4105CAQ	asparagine synthetase
GSH73_RS04305	ENOG4105BZ4	penicillin-binding protein
GSH73_RS04320	ENOG4105C08	Histidine kinase
GSH73_RS04325	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GSH73_RS04330	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GSH73_RS04335	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GSH73_RS04345	ENOG4105BZU	Histidine kinase
GSH73_RS04350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GSH73_RS04355	ENOG4105BZU	Histidine kinase
GSH73_RS04360	ENOG4107ZTW	SNARE associated Golgi
GSH73_RS04390	ENOG4107YEI	lmbE family
GSH73_RS04400	ENOG4105DR5	peptidase
GSH73_RS04405	ENOG4105CNI	cell division protein FtsW
GSH73_RS04415	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSH73_RS04420	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSH73_RS04445	ENOG4108JYZ	YitT family
GSH73_RS04455	ENOG4107QW8	radical SAM domain protein
GSH73_RS04465	ENOG4105D1F	ATP-binding protein
GSH73_RS04470	ENOG4107U53	septum site-determining protein minD
GSH73_RS04480	ENOG4107YM4	Beta-lactamase domain-containing protein
GSH73_RS04490	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS04495	ENOG4105BZU	Histidine kinase
GSH73_RS04505	ENOG4107RDB	Major Facilitator
GSH73_RS04510	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GSH73_RS04515	ENOG4105C4B	ABC transporter, permease
GSH73_RS04520	ENOG4105C0H	protease
GSH73_RS04540	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSH73_RS04545	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSH73_RS04555	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GSH73_RS04575	ENOG4105C1A	potassium transporter peripheral membrane
GSH73_RS04585	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GSH73_RS04600	ENOG4108ZVT	methylmalonyl-coA epimerase
GSH73_RS04605	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
GSH73_RS04615	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS04620	ENOG4105DFY	n-acylglucosamine 2-epimerase
GSH73_RS04625	ENOG4105HY2	Glycosidase related protein
GSH73_RS04635	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS04645	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS04660	ENOG4105CKB	glycosidase
GSH73_RS04665	ENOG4105CKB	glycosidase
GSH73_RS04685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSH73_RS04695	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
GSH73_RS04700	ENOG4105DT3	PTS system, galactitol-specific IIc component
GSH73_RS04705	ENOG4105D2N	Aldolase
GSH73_RS04735	ENOG4105E2R	ROK family
GSH73_RS04750	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GSH73_RS04755	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GSH73_RS04760	ENOG4107YGS	glycoside hydrolase 15-related
GSH73_RS04770	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
GSH73_RS04775	ENOG4106KNT	transcriptional regulator
GSH73_RS04785	ENOG4105XN3	extracellular solute-binding protein family 1
GSH73_RS04790	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS04795	ENOG4105DRS	transport system, permease
GSH73_RS04805	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GSH73_RS04820	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
GSH73_RS04840	ENOG4108MK9	spermidine N(1)-acetyltransferase
GSH73_RS04850	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS04855	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GSH73_RS04880	ENOG4105C0D	helicase
GSH73_RS04910	ENOG4108HRK	Histidine kinase
GSH73_RS04915	ENOG4105DY9	regulatoR
GSH73_RS04930	ENOG4105DA5	(ABC) transporter
GSH73_RS04950	ENOG4105BZU	Histidine kinase
GSH73_RS04960	ENOG4105CUB	amino acid
GSH73_RS04965	ENOG4107SCA	Formamidase (EC 3.5.1.49)
GSH73_RS04970	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS04975	ENOG4105BZ7	extracellular solute-binding protein family 1
GSH73_RS05020	ENOG4105BZ1	(ABC) transporter
GSH73_RS05030	ENOG4105DWF	phosphomethylpyrimidine kinase
GSH73_RS05045	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GSH73_RS05060	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
GSH73_RS05065	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
GSH73_RS05070	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
GSH73_RS05095	ENOG4108YZA	Nitrogen regulatory protein pii
GSH73_RS05120	ENOG4105C32	Amino acid ABC transporter (Permease)
GSH73_RS05125	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GSH73_RS05130	ENOG4105C0Z	ABC transporter
GSH73_RS05135	ENOG4108IV0	ABC, transporter
GSH73_RS05140	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GSH73_RS05145	ENOG4105E0C	molybdate abc transporter
GSH73_RS05155	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GSH73_RS05165	ENOG4108K8K	Transcriptional regulator
GSH73_RS05170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GSH73_RS05180	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
GSH73_RS05190	ENOG4105BZU	Histidine kinase
GSH73_RS05205	ENOG4108YZA	Nitrogen regulatory protein pii
GSH73_RS05210	ENOG4105C8Q	Methyl-accepting chemotaxis
GSH73_RS05215	ENOG4105CAQ	asparagine synthetase
GSH73_RS05225	ENOG4105CS2	ec 3.2.1.21
GSH73_RS05230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS05245	ENOG4108UH6	UPF0754 membrane protein
GSH73_RS05245	ENOG4108UH6	UPF0754 membrane protein
GSH73_RS05250	ENOG4105C22	threonyL-tRNA synthetase
GSH73_RS05260	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GSH73_RS05265	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GSH73_RS05270	ENOG4105VJV	50s ribosomal protein L35
GSH73_RS05275	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GSH73_RS05280	ENOG4108RWN	rrna methyltransferase
GSH73_RS05285	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GSH73_RS05290	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GSH73_RS05300	ENOG4105CFP	Peptidase U32
GSH73_RS05305	ENOG4105C98	muts2 protein
GSH73_RS05330	ENOG4105WH1	Two component transcriptional regulator luxr family
GSH73_RS05335	ENOG4105DFM	M18 family aminopeptidase
GSH73_RS05340	ENOG4105K4I	Scp-like extracellular
GSH73_RS05360	ENOG4107RE7	phosphate butyryltransferase
GSH73_RS05370	ENOG4105CKM	Branched-chain carboxylic acid kinase
GSH73_RS05405	ENOG4107SC7	Inner membrane transporter yjeM
GSH73_RS05410	ENOG4105DC7	peptidase M24
GSH73_RS05415	ENOG4105D82	Glutamate dehydrogenase
GSH73_RS05420	ENOG4105HDK	L-asparaginase
GSH73_RS05425	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GSH73_RS05435	ENOG4105D5P	Methylmalonyl-coA mutase
GSH73_RS05445	ENOG4108ZVT	methylmalonyl-coA epimerase
GSH73_RS05450	ENOG4105D9Q	decarboxylase (Beta subunit)
GSH73_RS05460	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GSH73_RS05465	ENOG4105DQU	oxidoreductase, subunit beta
GSH73_RS05480	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GSH73_RS05485	ENOG4108UIC	UPF0340 protein
GSH73_RS05490	ENOG4105IJJ	transcriptional regulator, crp fnr family
GSH73_RS05495	ENOG41082MP	copper ion binding protein
GSH73_RS05510	ENOG4105VRS	hydrolase family 18
GSH73_RS05515	ENOG41067S9	phage shock protein C, PspC
GSH73_RS05520	ENOG4105C85	amino acid
GSH73_RS05535	ENOG4105EMN	RNA polymerase sigma factor
GSH73_RS05550	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GSH73_RS05555	ENOG4105E4C	Lytic transglycosylase catalytic
GSH73_RS05560	ENOG4108VMM	UPF0756 membrane protein
GSH73_RS05590	ENOG4107TT5	NLP P60 protein
GSH73_RS05595	ENOG4105CI3	gtp-binding protein typa
GSH73_RS05600	ENOG4105E4C	Lytic transglycosylase catalytic
GSH73_RS05620	ENOG4108R3D	Electron transport complex
GSH73_RS05635	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
GSH73_RS05640	ENOG4106AFQ	Histidine kinase
GSH73_RS05650	ENOG4107QIZ	NADH dehydrogenase
GSH73_RS05655	ENOG4107QHI	-hydrogenase
GSH73_RS05665	ENOG4108Z03	MAF-like protein
GSH73_RS05670	ENOG4105W5Q	DNA repair protein (RadC
GSH73_RS05675	ENOG4105DFF	Rod shape-determining protein mreb
GSH73_RS05695	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GSH73_RS05700	ENOG4107QMS	site-determining protein
GSH73_RS05705	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GSH73_RS05710	ENOG4105CNI	cell division protein FtsW
GSH73_RS05715	ENOG4108Z5K	methylglyoxal synthase
GSH73_RS05720	ENOG4108K5P	(LipO)protein
GSH73_RS05740	ENOG4105C03	ribonuclease
GSH73_RS05745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GSH73_RS05755	ENOG4105K46	50S ribosomal protein l27
GSH73_RS05765	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSH73_RS05770	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GSH73_RS05775	ENOG4108WF2	Metal Dependent Phosphohydrolase
GSH73_RS05785	ENOG4105WWK	YheO domain protein
GSH73_RS05795	ENOG4105DZ1	carboxypeptidase
GSH73_RS05800	ENOG4105KQC	Competence protein
GSH73_RS05810	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GSH73_RS05815	ENOG4108W5N	phosphatidylglycerophosphatase a
GSH73_RS05820	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GSH73_RS05830	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
GSH73_RS05835	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
GSH73_RS05840	ENOG4105DRS	transport system, permease
GSH73_RS05845	ENOG4105BZ7	extracellular solute-binding protein family 1
GSH73_RS05855	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
GSH73_RS05860	ENOG4105BZ8	glutamate synthase
GSH73_RS05875	ENOG41084EF	Ferredoxin
GSH73_RS05880	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GSH73_RS05885	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GSH73_RS05910	ENOG4105CJ1	ABC, transporter
GSH73_RS05925	ENOG4107XGZ	Hydrolase
GSH73_RS05930	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GSH73_RS05935	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GSH73_RS05945	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GSH73_RS05955	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
GSH73_RS05975	ENOG4105CPK	Glycosyl transferase (Group 1
GSH73_RS05985	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GSH73_RS05990	ENOG4105CSA	Coproporphyrinogen iii oxidase
GSH73_RS06000	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GSH73_RS06005	ENOG4105CFG	Acts as a chaperone (By similarity)
GSH73_RS06010	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GSH73_RS06015	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GSH73_RS06020	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GSH73_RS06025	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GSH73_RS06030	ENOG4107YU2	histidine triad (hIT) protein
GSH73_RS06035	ENOG4105VCC	30S ribosomal protein S21
GSH73_RS06040	ENOG4105KTH	gatB Yqey
GSH73_RS06045	ENOG41068P3	sporulation protein YqfC
GSH73_RS06055	ENOG4105C9A	Phoh family
GSH73_RS06060	ENOG4105CTJ	Metal Dependent Phosphohydrolase
GSH73_RS06065	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GSH73_RS06070	ENOG4107YR5	Diacylglycerol kinase
GSH73_RS06075	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GSH73_RS06095	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GSH73_RS06100	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GSH73_RS06105	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GSH73_RS06135	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GSH73_RS06160	ENOG4105EP9	oxidoreductase
GSH73_RS06170	ENOG4105DFA	alanine racemase domain protein
GSH73_RS06175	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
GSH73_RS06185	ENOG4105DBK	s4 domain protein
GSH73_RS06200	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GSH73_RS06220	ENOG4105CRQ	synthase (Component I)
GSH73_RS06225	ENOG4105DDQ	anthranilate synthase
GSH73_RS06230	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GSH73_RS06235	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GSH73_RS06255	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSH73_RS06275	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GSH73_RS06285	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GSH73_RS06290	ENOG4105C34	Pseudouridine synthase
GSH73_RS06295	ENOG4105CUT	histidyl-tRNA synthetase
GSH73_RS06310	ENOG4105CUZ	uba thif-type nad fad binding protein
GSH73_RS06315	ENOG4105VPX	protein, conserved in bacteria
GSH73_RS06320	ENOG4105K63	Thioredoxin
GSH73_RS06345	ENOG4105D1H	recombination factor protein RarA
GSH73_RS06395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GSH73_RS06400	ENOG4105VBH	UPF0297 protein
GSH73_RS06410	ENOG41068XD	UPF0473 protein
GSH73_RS06415	ENOG4105I3K	Ferric uptake regulator, Fur family
GSH73_RS06420	ENOG4105CN5	Metallo-Beta-Lactamase
GSH73_RS06425	ENOG41084CE	UPF0342 protein
GSH73_RS06435	ENOG4108VQJ	O-methyltransferase
GSH73_RS06440	ENOG4105CFP	Peptidase U32
GSH73_RS06445	ENOG4107XRG	penicillin-binding protein
GSH73_RS06455	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GSH73_RS06485	ENOG4105VTR	Integrase
GSH73_RS06490	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS06500	ENOG4105E2X	shikimate dehydrogenase
GSH73_RS06505	ENOG4107QHF	type ii secretion system protein e
GSH73_RS06510	ENOG4105CZX	twitching motility protein
GSH73_RS06515	ENOG4105D7Q	type ii secretion system
GSH73_RS06525	ENOG4106A3R	peptidase
GSH73_RS06570	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GSH73_RS06575	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GSH73_RS06580	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GSH73_RS06585	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GSH73_RS06590	ENOG4105DC7	peptidase M24
GSH73_RS06595	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GSH73_RS06605	ENOG4105CD2	stage iii sporulation protein aa
GSH73_RS06620	ENOG4105KQ4	Stage iii sporulation protein ad
GSH73_RS06630	ENOG410644B	Stage III sporulation protein af
GSH73_RS06645	ENOG4108ZSR	alkaline shock protein
GSH73_RS06650	ENOG4105M7K	Involved in the transcription termination process (By similarity)
GSH73_RS06655	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GSH73_RS06660	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSH73_RS06665	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GSH73_RS06670	ENOG4105CTB	Polyprenyl synthetase
GSH73_RS06680	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GSH73_RS06685	ENOG4105DX0	Hemolysin A
GSH73_RS06690	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GSH73_RS06695	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GSH73_RS06700	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GSH73_RS06705	ENOG4105S1Z	Stage IV sporulation protein B
GSH73_RS06710	ENOG4107QQR	Sporulation
GSH73_RS06740	ENOG4108YZ4	nudix hydrolase
GSH73_RS06750	ENOG4105MZ9	stage II sporulation protein m
GSH73_RS06755	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSH73_RS06760	ENOG4105DZ1	carboxypeptidase
GSH73_RS06765	ENOG41082AN	stage II sporulation protein
GSH73_RS06770	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
GSH73_RS06775	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS06780	ENOG41084UG	Pfam:DUF1458
GSH73_RS06785	ENOG41090VF	Stage v sporulation protein ac
GSH73_RS06800	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GSH73_RS06805	ENOG4108Z4T	Peptidase M50
GSH73_RS06810	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GSH73_RS06815	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GSH73_RS06825	ENOG4105KBJ	sporulation protein ytfj
GSH73_RS06830	ENOG4105DZ1	carboxypeptidase
GSH73_RS06840	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GSH73_RS06845	ENOG4105FE9	pseudouridine synthase
GSH73_RS06855	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GSH73_RS06860	ENOG4105CYW	agmatinase
GSH73_RS06865	ENOG4107QSA	Oxaloacetate decarboxylase
GSH73_RS06870	ENOG4106678	morphogenetic protein associated with SpoVID
GSH73_RS06880	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GSH73_RS06885	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GSH73_RS06895	ENOG4105CBX	hi0933 family
GSH73_RS06905	ENOG4105CAT	Cytidine monophosphate kinase
GSH73_RS06915	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GSH73_RS06920	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GSH73_RS06925	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
GSH73_RS06930	ENOG4105BZU	Histidine kinase
GSH73_RS06945	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GSH73_RS06950	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GSH73_RS06955	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GSH73_RS06960	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GSH73_RS06965	ENOG4105II7	pyrroline-5-carboxylate reductase
GSH73_RS06970	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GSH73_RS06975	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GSH73_RS06980	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GSH73_RS06985	ENOG4105CXI	aluminum resistance protein
GSH73_RS06990	ENOG4106F1P	AAA ATPase, central domain protein
GSH73_RS06995	ENOG4105C5S	asparaginyl-tRNA synthetase
GSH73_RS07010	ENOG4105DB7	PHP domain protein
GSH73_RS07015	ENOG4105MCT	stage V sporulation protein S
GSH73_RS07020	ENOG4105D48	metallophosphoesterase
GSH73_RS07030	ENOG4105EYH	Exonuclease
GSH73_RS07055	ENOG410902V	Modulates RecA activity (By similarity)
GSH73_RS07060	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GSH73_RS07065	ENOG4105CEV	competence damage-inducible protein
GSH73_RS07070	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GSH73_RS07075	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GSH73_RS07080	ENOG4105CNU	cell division protein FtsK
GSH73_RS07090	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
GSH73_RS07105	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GSH73_RS07110	ENOG4105C1V	Peptidase, M16
GSH73_RS07120	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GSH73_RS07125	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GSH73_RS07135	ENOG4105DTN	riboflavin biosynthesis protein ribF
GSH73_RS07140	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GSH73_RS07145	ENOG4105SFS	phosphoesterase RecJ domain protein
GSH73_RS07150	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GSH73_RS07165	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
GSH73_RS07170	ENOG4105CHV	Transcription elongation factor NusA
GSH73_RS07175	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GSH73_RS07180	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GSH73_RS07190	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GSH73_RS07195	ENOG4105DZP	Membrane-associated zinc metalloprotease
GSH73_RS07200	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GSH73_RS07205	ENOG4105KNE	Phosphatidate cytidylyltransferase
GSH73_RS07210	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GSH73_RS07215	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GSH73_RS07220	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GSH73_RS07225	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GSH73_RS07230	ENOG4105CE9	30S ribosomal protein S2
GSH73_RS07245	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS07250	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
GSH73_RS07260	ENOG4108V3W	Chemotaxis protein, CheW
GSH73_RS07265	ENOG4105CBS	Chea signal transduction histidine kinase
GSH73_RS07280	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GSH73_RS07285	ENOG4105D7B	Flagellar biosynthesis protein flha
GSH73_RS07290	ENOG4105D00	flagellar biosynthetic protein flhB
GSH73_RS07295	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GSH73_RS07300	ENOG4105VS8	Flagellar biosynthetic protein fliq
GSH73_RS07305	ENOG4105CN7	Flagellar biosynthetic protein FliP
GSH73_RS07315	ENOG4107YTP	response regulator receiver protein
GSH73_RS07320	ENOG4105DD5	Flagellar motor switch protein
GSH73_RS07325	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GSH73_RS07340	ENOG4105BZE	flagellar hook protein, FlgE
GSH73_RS07345	ENOG410822I	Flagellar hook capping protein
GSH73_RS07375	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GSH73_RS07380	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GSH73_RS07385	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GSH73_RS07390	ENOG4108ZC9	flagellar basal-body rod protein flgc
GSH73_RS07395	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GSH73_RS07405	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GSH73_RS07410	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GSH73_RS07415	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GSH73_RS07425	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GSH73_RS07430	ENOG4105VFF	UPF0102 protein
GSH73_RS07435	ENOG4105C31	Tryptophanyl-tRNA synthetase
GSH73_RS07440	ENOG4105C0P	Mg chelatase subunit ChlI
GSH73_RS07450	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GSH73_RS07455	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GSH73_RS07460	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GSH73_RS07465	ENOG4105VB6	UPF0109 protein
GSH73_RS07470	ENOG4105K5M	30s ribosomal protein S16
GSH73_RS07480	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
GSH73_RS07485	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GSH73_RS07490	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GSH73_RS07495	ENOG4105MCT	stage V sporulation protein S
GSH73_RS07500	ENOG4105D4P	Coproporphyrinogen iii oxidase
GSH73_RS07505	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GSH73_RS07510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GSH73_RS07515	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GSH73_RS07520	ENOG4105CHR	reductase
GSH73_RS07525	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GSH73_RS07530	ENOG4105EA8	2-Nitropropane dioxygenase
GSH73_RS07535	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GSH73_RS07540	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GSH73_RS07545	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
GSH73_RS07550	ENOG41067VY	50S ribosomal protein L32
GSH73_RS07555	ENOG4105KNH	Nucleic acid-binding protein
GSH73_RS07560	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GSH73_RS07565	ENOG4108IJ2	phosphate acetyltransferase
GSH73_RS07575	ENOG4105H20	Sporulation integral membrane protein YlbJ
GSH73_RS07585	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GSH73_RS07590	ENOG4106H78	methyltransferase
GSH73_RS07605	ENOG4105EPR	degv family
GSH73_RS07610	ENOG4105CB5	ATP-dependent DNA helicase recG
GSH73_RS07615	ENOG4105DP4	dak2 domain fusion protein ylov
GSH73_RS07620	ENOG4108ZSR	alkaline shock protein
GSH73_RS07640	ENOG4105DJV	ribulose-phosphate 3-epimerase
GSH73_RS07645	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GSH73_RS07650	ENOG4105D9P	serine threonine protein kinase
GSH73_RS07655	ENOG4108ZF3	Phosphatase
GSH73_RS07660	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GSH73_RS07680	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GSH73_RS07685	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GSH73_RS07690	ENOG4105C25	Primosomal protein n'
GSH73_RS07695	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GSH73_RS07705	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GSH73_RS07715	ENOG4105DSJ	YicC domain protein
GSH73_RS07720	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GSH73_RS07725	ENOG4105F23	Fibronectin-binding protein
GSH73_RS07755	ENOG4105DR4	Methyltransferase
GSH73_RS07760	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GSH73_RS07765	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GSH73_RS07770	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GSH73_RS07780	ENOG4105CD3	dihydroorotase
GSH73_RS07785	ENOG4105CXT	aspartate transcarbamylase
GSH73_RS07790	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GSH73_RS07800	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
GSH73_RS07805	ENOG4105C5X	domain protein
GSH73_RS07815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GSH73_RS07820	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GSH73_RS07825	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GSH73_RS07840	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GSH73_RS07845	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GSH73_RS07870	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GSH73_RS07875	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GSH73_RS07880	ENOG4105JFG	SpoIID LytB domain protein
GSH73_RS07885	ENOG41061AI	Protein of unknown function (DUF2905)
GSH73_RS07890	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GSH73_RS07895	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GSH73_RS07900	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GSH73_RS07910	ENOG4108V3W	Chemotaxis protein, CheW
GSH73_RS07915	ENOG4105CDY	transcriptional regulatory protein
GSH73_RS07940	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GSH73_RS07945	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GSH73_RS07955	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GSH73_RS07985	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS07995	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GSH73_RS08000	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GSH73_RS08010	ENOG4105VFE	sira family
GSH73_RS08020	ENOG4105D06	uba thif-type nad fad binding protein
GSH73_RS08025	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GSH73_RS08035	ENOG4105D52	delta-aminolevulinic acid dehydratase
GSH73_RS08040	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GSH73_RS08045	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GSH73_RS08055	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GSH73_RS08060	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GSH73_RS08085	ENOG4105E43	Extracellular solute-binding protein, family 5
GSH73_RS08095	ENOG4105NBF	ammecr1 domain protein
GSH73_RS08100	ENOG4107SWG	transcriptional regulator MERR family
GSH73_RS08105	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSH73_RS08110	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
GSH73_RS08115	ENOG4105CXN	decarboxylase
GSH73_RS08125	ENOG4105EB3	Histidine kinase
GSH73_RS08135	ENOG4105K63	Thioredoxin
GSH73_RS08140	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSH73_RS08145	ENOG4107QIV	Cytochrome c biogenesis protein
GSH73_RS08150	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GSH73_RS08155	ENOG41066F8	ROK family
GSH73_RS08190	ENOG4105GR3	Histidine kinase
GSH73_RS08195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GSH73_RS08200	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GSH73_RS08210	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GSH73_RS08215	ENOG4105CQC	Prephenate dehydratase
GSH73_RS08220	ENOG4105D49	3-dehydroquinate synthase
GSH73_RS08225	ENOG4105EJQ	L-serine dehydratase
GSH73_RS08235	ENOG4105DPN	Oligoendopeptidase f
GSH73_RS08245	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
GSH73_RS08250	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GSH73_RS08260	ENOG4105CNW	domain protein
GSH73_RS08270	ENOG41066FP	Small acid-soluble spore protein I
GSH73_RS08280	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GSH73_RS08285	ENOG4108UVJ	appr-1-p processing domain protein
GSH73_RS08295	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GSH73_RS08315	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
GSH73_RS08325	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GSH73_RS08360	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GSH73_RS08365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GSH73_RS08370	ENOG4105E2Z	phosphate ABC transporter (Permease
GSH73_RS08375	ENOG4105C8U	phosphate abc transporter
GSH73_RS08380	ENOG4105C8Q	Methyl-accepting chemotaxis
GSH73_RS08385	ENOG4105CVA	phosphate
GSH73_RS08390	ENOG4105BZU	Histidine kinase
GSH73_RS08395	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GSH73_RS08410	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS08415	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GSH73_RS08425	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GSH73_RS08430	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GSH73_RS08435	ENOG4105K67	small basic protein
GSH73_RS08450	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GSH73_RS08455	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GSH73_RS08460	ENOG4105CNI	cell division protein FtsW
GSH73_RS08470	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GSH73_RS08475	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GSH73_RS08480	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GSH73_RS08485	ENOG4105CJN	penicillin-binding protein
GSH73_RS08520	ENOG4105C3G	gtp-binding protein
GSH73_RS08525	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GSH73_RS08550	ENOG4105Y5S	NADH ubiquinone oxidoreductase, 24 kD
GSH73_RS08560	ENOG4105VPX	protein, conserved in bacteria
GSH73_RS08565	ENOG4107SBE	Glycosyl transferase (Group 1
GSH73_RS08600	ENOG4107EF8	Glycosyl transferase (Group 1
GSH73_RS08605	ENOG4105DR5	peptidase
GSH73_RS08615	ENOG4105VRS	hydrolase family 18
GSH73_RS08630	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GSH73_RS08635	ENOG4105DYB	Isoaspartyl dipeptidase
GSH73_RS08655	ENOG4105BZU	Histidine kinase
GSH73_RS08675	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GSH73_RS08680	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSH73_RS08685	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GSH73_RS08690	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GSH73_RS08705	ENOG4108ZJ4	polysaccharide deacetylase
GSH73_RS08710	ENOG4107URF	beta-phospho-glucomutase
GSH73_RS08730	ENOG4107FKK	extracellular solute-binding protein family 1
GSH73_RS08735	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS08740	ENOG4105DRS	transport system, permease
GSH73_RS08745	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS08760	ENOG4107KJX	Transcriptional regulator
GSH73_RS08780	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GSH73_RS08810	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GSH73_RS08820	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GSH73_RS08825	ENOG4107ZYJ	bioY protein
GSH73_RS08830	ENOG4105C8M	UPF0272 protein
GSH73_RS08835	ENOG4105C8M	UPF0272 protein
GSH73_RS08840	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
GSH73_RS08850	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
GSH73_RS08860	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GSH73_RS08865	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GSH73_RS08870	ENOG4105CNW	domain protein
GSH73_RS08885	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GSH73_RS08890	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GSH73_RS08910	ENOG4108K88	Membrane
GSH73_RS08920	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GSH73_RS08945	ENOG41069HH	4-oxalocrotonate tautomerase
GSH73_RS08955	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GSH73_RS08975	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
GSH73_RS08980	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
GSH73_RS08985	ENOG4105XN3	extracellular solute-binding protein family 1
GSH73_RS09005	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS09020	ENOG4108HRK	Histidine kinase
GSH73_RS09025	ENOG4105EQD	regulatoR
GSH73_RS09025	ENOG4105EQD	regulatoR
GSH73_RS09030	ENOG4105I82	acetyl xylan esterase
GSH73_RS09065	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS09075	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GSH73_RS09125	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
GSH73_RS09130	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
GSH73_RS09140	ENOG4105D2X	ABC transporter substrate-binding protein
GSH73_RS09150	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
GSH73_RS09170	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GSH73_RS09175	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GSH73_RS09180	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GSH73_RS09185	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GSH73_RS09190	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GSH73_RS09195	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GSH73_RS09200	ENOG41082I9	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GSH73_RS09205	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
GSH73_RS09210	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GSH73_RS09215	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GSH73_RS09225	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GSH73_RS09230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GSH73_RS09235	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GSH73_RS09240	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GSH73_RS09245	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GSH73_RS09250	ENOG4105VUF	Transcriptional regulator
GSH73_RS09280	ENOG4105CPC	Aldo Keto reductase
GSH73_RS09300	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
GSH73_RS09305	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
GSH73_RS09310	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSH73_RS09325	ENOG4105WEF	catalase
GSH73_RS09330	ENOG4105C3R	Methionine synthase
GSH73_RS09370	ENOG4108RCM	Nitroreductase
GSH73_RS09375	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GSH73_RS09380	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GSH73_RS09385	ENOG4105EUK	rtx toxin RtxA
GSH73_RS09395	ENOG4105DVT	helicase
GSH73_RS09410	ENOG4108DBC	nitroreductase
GSH73_RS09435	ENOG4105BZU	Histidine kinase
GSH73_RS09445	ENOG4107Y80	Major Facilitator superfamily
GSH73_RS09475	ENOG4105DQ6	Transposase
GSH73_RS09495	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GSH73_RS09515	ENOG4105CTQ	phosphohexokinase
GSH73_RS09525	ENOG4105C0B	DNA polymerase III (alpha subunit)
GSH73_RS09535	ENOG4105KRI	phosphocarrier protein (HPr
GSH73_RS09540	ENOG4105CIE	May be required for sporulation (By similarity)
GSH73_RS09555	ENOG4108IUK	alpha amylase, catalytic
GSH73_RS09575	ENOG4105EG2	ABC transporter, permease
GSH73_RS09580	ENOG4105D56	permease protein
GSH73_RS09585	ENOG4107FKK	extracellular solute-binding protein family 1
GSH73_RS09590	ENOG4105C8Q	Methyl-accepting chemotaxis
GSH73_RS09630	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GSH73_RS09635	ENOG4105DCG	PHP domain protein
GSH73_RS09640	ENOG4105D4A	Cell wall formation (By similarity)
GSH73_RS09645	ENOG4105C59	p-type ATPase
GSH73_RS09670	ENOG4105DA5	(ABC) transporter
GSH73_RS09690	ENOG4105EMN	RNA polymerase sigma factor
GSH73_RS09695	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GSH73_RS09705	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GSH73_RS09725	ENOG4105DCG	PHP domain protein
GSH73_RS09735	ENOG41082MP	copper ion binding protein
GSH73_RS09740	ENOG4107QZT	geranylgeranyl reductase
GSH73_RS09745	ENOG4105CVG	Homoserine O-transsuccinylase
GSH73_RS09755	ENOG4105EXC	Acyl-transferase
GSH73_RS09780	ENOG4105FDF	Could be involved in DNA repair (By similarity)
GSH73_RS09785	ENOG4105DQE	DNA ligase
GSH73_RS09790	ENOG4105CJN	penicillin-binding protein
GSH73_RS09800	ENOG4105CJ2	(LipO)protein
GSH73_RS09830	ENOG4105E2R	ROK family
GSH73_RS09835	ENOG4105CMR	udp-glucose 4-epimerase
GSH73_RS09840	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GSH73_RS09845	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
GSH73_RS09875	ENOG4108MDK	Dehydrogenase
GSH73_RS09880	ENOG4105CMD	Transcriptional regulator, GntR family
GSH73_RS09890	ENOG4105CR5	Class II aldolase adducin family protein
GSH73_RS09895	ENOG4105EF1	ribulokinase
GSH73_RS09900	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GSH73_RS09905	ENOG4105CNN	ABC, transporter
GSH73_RS09910	ENOG4105C2J	ABC transporter
GSH73_RS09915	ENOG4105CNN	ABC, transporter
GSH73_RS09925	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GSH73_RS09930	ENOG4105CJQ	hydrolase, family 31
GSH73_RS09935	ENOG4105C4C	beta-galactosidase
GSH73_RS09955	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS09965	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS09970	ENOG4105CS2	ec 3.2.1.21
GSH73_RS09990	ENOG4105CYT	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GSH73_RS09995	ENOG4105VCP	PTS System
GSH73_RS10000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GSH73_RS10005	ENOG4105CNT	hydrolase family 2
GSH73_RS10010	ENOG4105D9R	oxidoreductase
GSH73_RS10015	ENOG4105WZ4	isomerase
GSH73_RS10025	ENOG4105CK5	oxidoreductase
GSH73_RS10030	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS10035	ENOG4105CEY	Amp-dependent synthetase and ligase
GSH73_RS10040	ENOG4105DKQ	ROK family
GSH73_RS10050	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GSH73_RS10055	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GSH73_RS10065	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS10080	ENOG4105CJN	penicillin-binding protein
GSH73_RS10090	ENOG4105HZM	Fha domain containing protein
GSH73_RS10100	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GSH73_RS10105	ENOG4108N5B	2-phosphosulfolactate phosphatase
GSH73_RS10115	ENOG4105CN1	protease
GSH73_RS10120	ENOG4105DR5	peptidase
GSH73_RS10125	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GSH73_RS10130	ENOG4105CAK	Cell division ATP-binding protein ftsE
GSH73_RS10135	ENOG4107VHA	regulatoR
GSH73_RS10140	ENOG4105EYU	Glutamine amido-transferase
GSH73_RS10145	ENOG4105CBC	glutamate synthase
GSH73_RS10150	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GSH73_RS10180	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GSH73_RS10200	ENOG4105CJ1	ABC, transporter
GSH73_RS10220	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GSH73_RS10255	ENOG4105CFG	Acts as a chaperone (By similarity)
GSH73_RS10265	ENOG4105VDH	Dihydroxyacetone kinase
GSH73_RS10275	ENOG4105CMT	Dihydroxyacetone kinase
GSH73_RS10280	ENOG4108JUB	Transcriptional regulator
GSH73_RS10300	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GSH73_RS10305	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GSH73_RS10320	ENOG4105D6J	arsenicaL-resistance protein
GSH73_RS10330	ENOG4108X8W	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GSH73_RS10335	ENOG41076QQ	Glycosyl transferase, family 2
GSH73_RS10350	ENOG4105KTU	Transcriptional regulator, arsr family
GSH73_RS10390	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GSH73_RS10395	ENOG4108IGT	Dipeptidase
GSH73_RS10400	ENOG4107YEI	lmbE family
GSH73_RS10405	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GSH73_RS10420	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GSH73_RS10425	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GSH73_RS10435	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GSH73_RS10440	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GSH73_RS10445	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GSH73_RS10455	ENOG4107QX8	SPFH domain, Band 7 family protein
GSH73_RS10465	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
GSH73_RS10470	ENOG4105E2V	Glycosyltransferase 36
GSH73_RS10475	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GSH73_RS10480	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GSH73_RS10490	ENOG4105DRS	transport system, permease
GSH73_RS10495	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GSH73_RS10515	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
GSH73_RS10525	ENOG4107YY3	extracellular solute-binding protein family 1
GSH73_RS10530	ENOG4107KJX	Transcriptional regulator
GSH73_RS10550	ENOG4105CK5	oxidoreductase
GSH73_RS10560	ENOG4105VCQ	rubredoxin
GSH73_RS10570	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GSH73_RS10580	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GSH73_RS10615	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
GSH73_RS10625	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GSH73_RS10635	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GSH73_RS10650	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GSH73_RS10655	ENOG4105EEM	helicase
GSH73_RS10670	ENOG410828M	hemerythrin-like, metal-binding protein
GSH73_RS10675	ENOG410667J	hydrolase
GSH73_RS10685	ENOG4105K5X	acetyltransferase
GSH73_RS10715	ENOG4105KBH	arsR family transcriptional regulator
GSH73_RS10730	ENOG4107SXA	Phosphorylase
GSH73_RS10765	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
GSH73_RS10860	ENOG4105KY5	gCN5-related N-acetyltransferase
GSH73_RS10870	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GSH73_RS10875	ENOG4108D32	Methyltransferase
GSH73_RS10960	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GSH73_RS10970	ENOG4105E9Q	Acyl-transferase
GSH73_RS11005	ENOG4105C8B	TIGR00159 family
GSH73_RS11025	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GSH73_RS11035	ENOG41068JE	domain protein
GSH73_RS11060	ENOG4107SMJ	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GSH73_RS11075	ENOG4108JB8	alcohol dehydrogenase
GSH73_RS11140	ENOG4108UJD	30S ribosomal protein S9
GSH73_RS11145	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GSH73_RS11150	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GSH73_RS11155	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
GSH73_RS11160	ENOG4108JJB	ABC transporter
GSH73_RS11165	ENOG4108JJB	ABC transporter
GSH73_RS11170	ENOG4108ZT0	50S ribosomal protein l17
GSH73_RS11175	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSH73_RS11180	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GSH73_RS11185	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GSH73_RS11190	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSH73_RS11195	ENOG41067V7	50S ribosomal protein L36
GSH73_RS11200	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GSH73_RS11215	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GSH73_RS11220	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GSH73_RS11225	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GSH73_RS11230	ENOG4105VPB	50S ribosomal protein L30
GSH73_RS11235	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GSH73_RS11240	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GSH73_RS11250	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GSH73_RS11255	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GSH73_RS11260	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSH73_RS11265	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GSH73_RS11270	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GSH73_RS11275	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GSH73_RS11280	ENOG41082SA	50s ribosomal protein l29
GSH73_RS11285	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GSH73_RS11290	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GSH73_RS11295	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GSH73_RS11300	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GSH73_RS11305	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSH73_RS11310	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GSH73_RS11315	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GSH73_RS11320	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GSH73_RS11325	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GSH73_RS11335	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GSH73_RS11340	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GSH73_RS11345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GSH73_RS11350	ENOG4105XPM	ribosomal protein
GSH73_RS11355	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSH73_RS11360	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GSH73_RS11365	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GSH73_RS11380	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GSH73_RS11385	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GSH73_RS11390	ENOG410683Z	Preprotein translocase SecE subunit
GSH73_RS11395	ENOG4105WDJ	50S ribosomal protein L33
GSH73_RS11400	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GSH73_RS11415	ENOG4105M0M	Tetracycline resistance protein
GSH73_RS11420	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GSH73_RS11430	ENOG4105C8N	cysteinyl-tRNA synthetase
GSH73_RS11435	ENOG4105D7W	serine acetyltransferase
GSH73_RS11440	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GSH73_RS11455	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GSH73_RS11465	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GSH73_RS11470	ENOG4105CTP	PilT protein domain protein
GSH73_RS11480	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GSH73_RS11490	ENOG41066A3	ATP guanido phosphotransferase
GSH73_RS11495	ENOG4108Z0C	Uvrb UvrC protein
GSH73_RS11510	ENOG4105C6K	Malic enzyme
GSH73_RS11515	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GSH73_RS11520	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GSH73_RS11525	ENOG4108YRF	PTS System
GSH73_RS11530	ENOG4105DM4	PTS System
GSH73_RS11535	ENOG4105DM4	PTS System
GSH73_RS11545	ENOG4105BZU	Histidine kinase
GSH73_RS11550	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GSH73_RS11570	ENOG410867B	UPF0291 protein
GSH73_RS11575	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GSH73_RS11580	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GSH73_RS11585	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSH73_RS11590	ENOG4105EEI	dihydropteroate synthase
GSH73_RS11595	ENOG4105EUJ	GTP cyclohydrolase i
GSH73_RS11600	ENOG4105CRK	lysyL-tRNA synthetase
GSH73_RS11605	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GSH73_RS11635	ENOG4105E1K	spore germination protein
GSH73_RS11645	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GSH73_RS11650	ENOG4105FH5	Membrane
GSH73_RS11655	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
GSH73_RS11660	ENOG4107QX3	carboxylase
GSH73_RS11670	ENOG4105CKU	formyltetrahydrofolate synthetase
GSH73_RS11675	ENOG4105BZU	Histidine kinase
GSH73_RS11685	ENOG4105ID8	Transcriptional regulator, ARAC family
GSH73_RS11695	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GSH73_RS11700	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GSH73_RS11705	ENOG4105D9P	serine threonine protein kinase
GSH73_RS11725	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GSH73_RS11750	ENOG41089UC	methyltransferase, type 11
GSH73_RS11760	ENOG4105VUC	UPF0237 protein
GSH73_RS11810	ENOG4107Z3H	Transcriptional regulator, TetR family
GSH73_RS11820	ENOG4105CJ1	ABC, transporter
GSH73_RS11825	ENOG4107QWP	ABC-2 type transporter
GSH73_RS11845	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GSH73_RS11860	ENOG4105FKZ	Methyl-accepting chemotaxis
GSH73_RS11890	ENOG4105D49	3-dehydroquinate synthase
GSH73_RS11895	ENOG41060GV	RNA binding s1 domain protein
GSH73_RS11920	ENOG4105VYY	sporulation protein yabp
GSH73_RS11930	ENOG41082I2	s4 domain protein
GSH73_RS11935	ENOG4105K70	DNA-binding protein
GSH73_RS11940	ENOG4108IY2	MazG family
GSH73_RS11960	ENOG4108IJ0	Aspartate ammonia-lyase
GSH73_RS11965	ENOG4105MAX	Superoxide reductase
GSH73_RS11970	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GSH73_RS11975	ENOG4105KST	dependent repressor
GSH73_RS11980	ENOG4105DQR	SNARE associated Golgi
GSH73_RS11985	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GSH73_RS11995	ENOG4105CH7	arginosuccinase
GSH73_RS12010	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GSH73_RS12015	ENOG4105C8Y	Acetylornithine aminotransferase
GSH73_RS12025	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GSH73_RS12030	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GSH73_RS12070	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
GSH73_RS12085	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GSH73_RS12095	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
GSH73_RS12100	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GSH73_RS12125	ENOG4105C0X	amino acid
GSH73_RS12135	ENOG4105WH1	Two component transcriptional regulator luxr family
GSH73_RS12155	ENOG4105CJ1	ABC, transporter
GSH73_RS12160	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
GSH73_RS12165	ENOG4105C75	arginyL-tRNA synthetase
GSH73_RS12175	ENOG4105CPF	Cell wall formation (By similarity)
GSH73_RS12180	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GSH73_RS12195	ENOG4105DBV	ornithine carbamoyltransferase
GSH73_RS12200	ENOG4105CEU	Arginine dihydrolase
GSH73_RS12205	ENOG4105CUB	amino acid
GSH73_RS12210	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GSH73_RS12220	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS12225	ENOG4105DRS	transport system, permease
GSH73_RS12245	ENOG4105MSI	germination protein ypeb
GSH73_RS12255	ENOG4105CXN	decarboxylase
GSH73_RS12260	ENOG4108ZXQ	stage ii sporulation protein r
GSH73_RS12265	ENOG4108Q5U	germination protein, ger(x)c family
GSH73_RS12270	ENOG4108Q8B	Spore germination protein
GSH73_RS12290	ENOG4105DRR	Transcriptional regulator, GntR family
GSH73_RS12305	ENOG4105W42	Veg protein
GSH73_RS12310	ENOG4105XFA	sporulation peptidase YabG
GSH73_RS12315	ENOG4108M14	stage v sporulation protein t
GSH73_RS12320	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GSH73_RS12325	ENOG4108JA2	transcriptioN-repair coupling factor
GSH73_RS12340	ENOG4105C0H	protease
GSH73_RS12345	ENOG4105BZU	Histidine kinase
GSH73_RS12355	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GSH73_RS12360	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GSH73_RS12370	ENOG4105DFT	pur operon repressor
GSH73_RS12375	ENOG4105DFU	Cell wall formation (By similarity)
GSH73_RS12380	ENOG4105ETE	Transcriptional regulator (LacI family
GSH73_RS12390	ENOG4105VN1	Heat shock protein
GSH73_RS12430	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GSH73_RS12455	ENOG4107RR1	TRANSCRIPTIONal
GSH73_RS12500	ENOG4105D5B	Sulfite reductase, subunit A
GSH73_RS12505	ENOG4107SHJ	sulfite reductase subunit b
GSH73_RS12510	ENOG410810Y	Sulfite reductase
GSH73_RS12520	ENOG4107VXZ	Hydrolase
GSH73_RS12550	ENOG4105CKB	glycosidase
GSH73_RS12555	ENOG4105EG2	ABC transporter, permease
GSH73_RS12570	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GSH73_RS12580	ENOG4105C1J	atp-dependent rna helicase
GSH73_RS12595	ENOG4105C45	hydrogenase expression formation protein (HypE)
GSH73_RS12600	ENOG4105CQS	hydrogenase expression formation protein HypD
GSH73_RS12615	ENOG4107RSS	Hydrogenase accessory protein HypB
GSH73_RS12620	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
GSH73_RS12625	ENOG4107X8D	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GSH73_RS12630	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
GSH73_RS12640	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GSH73_RS12650	ENOG4105D65	subunit l
GSH73_RS12685	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GSH73_RS12690	ENOG41069ER	domain protein
GSH73_RS12700	ENOG4105F8V	Hydrolase, tatD family
GSH73_RS12755	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GSH73_RS12770	ENOG4108JIC	nucleoside recognition domain protein
GSH73_RS12775	ENOG4105KRN	Transcriptional regulator, abrb family
GSH73_RS12785	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GSH73_RS12790	ENOG41060K3	Methyltransferase
GSH73_RS12795	ENOG4105CEU	Arginine dihydrolase
GSH73_RS12815	ENOG4105MA4	psp1 domain protein
GSH73_RS12820	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GSH73_RS12830	ENOG4105X0R	protein from nitrogen regulatory protein P-II
GSH73_RS12835	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GSH73_RS12840	ENOG4105CXN	decarboxylase
GSH73_RS12850	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GSH73_RS12875	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GSH73_RS12885	ENOG4106DSS	Tartrate dehydratase subunit alpha
GSH73_RS12890	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GSH73_RS12895	ENOG4105F1A	Pyruvate formate-lyase
GSH73_RS12900	ENOG4105C6N	Formate acetyltransferase
GSH73_RS12925	ENOG4105CHR	reductase
GSH73_RS12980	ENOG4105DHT	Metal Dependent Phosphohydrolase
GSH73_RS12990	ENOG41087RV	Protein CrcB homolog
GSH73_RS12995	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GSH73_RS13000	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GSH73_RS13005	ENOG4105C6E	dna polymerase iii
GSH73_RS13010	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GSH73_RS13030	ENOG4108Z6B	deaminase
GSH73_RS13100	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GSH73_RS13105	ENOG4105EQR	Transposase IS116 IS110 IS902
GSH73_RS13120	ENOG4108PQP	glycosyl transferase group 1
GSH73_RS13130	ENOG4105CPK	Glycosyl transferase (Group 1
GSH73_RS13135	ENOG4105K64	Glycosyl transferase, family 2
GSH73_RS13185	ENOG4105DTT	CRISPR-associated helicase, cas3
GSH73_RS13205	ENOG4105DJZ	UPF0182 protein
GSH73_RS13225	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GSH73_RS13235	ENOG4108REF	Sporulation integral membrane protein ytvi
GSH73_RS13250	ENOG4108R6K	riboflavin synthase, subunit alpha
GSH73_RS13255	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GSH73_RS13260	ENOG4105C7K	acetolactate synthase
GSH73_RS13265	ENOG4105C01	Dihydroxy-acid dehydratase
GSH73_RS13270	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GSH73_RS13275	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GSH73_RS13285	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GSH73_RS13290	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GSH73_RS13310	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSH73_RS13315	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GSH73_RS13325	ENOG4105F1K	Glutamine amidotransferase
