locus-tag	class	description
Thert_RS00005	COG0582	viral genome integration into host DNA
Thert_RS00040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Thert_RS00070	COG0512	Glutamine amidotransferase of anthranilate synthase
Thert_RS00070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Thert_RS00090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Thert_RS00105	COG3599	regulation of cell shape
Thert_RS00110	COG2302	S4 RNA-binding domain
Thert_RS00125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Thert_RS00160	COG0557	exoribonuclease II activity
Thert_RS00180	COG0574	Belongs to the PEP-utilizing enzyme family
Thert_RS00180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Thert_RS00190	COG0423	glycine-tRNA ligase activity
Thert_RS00215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Thert_RS00225	COG1480	7TM receptor with intracellular HD hydrolase
Thert_RS00230	COG1702	phosphate starvation-inducible protein PhoH
Thert_RS00245	COG1610	YqeY-like protein
Thert_RS00255	COG0537	adenosine 5'-monophosphoramidase activity
Thert_RS00260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Thert_RS00265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Thert_RS00270	COG2264	protein methyltransferase activity
Thert_RS00275	COG0484	heat shock protein binding
Thert_RS00285	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Thert_RS00295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Thert_RS00300	COG0481	GTPase activity
Thert_RS00330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Thert_RS00340	COG0268	Binds directly to 16S ribosomal RNA
Thert_RS00350	COG0658	competence protein
Thert_RS00350	COG2333	competence protein COMEC
Thert_RS00355	COG1234	tRNA 3'-trailer cleavage
Thert_RS00375	COG1131	(ABC) transporter
Thert_RS00400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Thert_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Thert_RS00430	COG0493	'glutamate synthase
Thert_RS00455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Thert_RS00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Thert_RS00465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Thert_RS00475	COG1555	photosystem II stabilization
Thert_RS00475	COG1596	polysaccharide export
Thert_RS00480	COG1686	Belongs to the peptidase S11 family
Thert_RS00485	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Thert_RS00490	COG2964	Protein conserved in bacteria
Thert_RS00495	COG0799	negative regulation of ribosome biogenesis
Thert_RS00500	COG1713	HD superfamily hydrolase involved in NAD metabolism
Thert_RS00535	COG1530	ribonuclease E activity
Thert_RS00550	COG0517	IMP dehydrogenase activity
Thert_RS00550	COG1994	Peptidase M50
Thert_RS00555	COG1388	LysM domain
Thert_RS00555	COG0739	heme binding
Thert_RS00565	COG0772	Belongs to the SEDS family
Thert_RS00575	COG2894	cell division
Thert_RS00600	COG1077	Cell shape determining protein MreB Mrl
Thert_RS00605	COG2003	Belongs to the UPF0758 family
Thert_RS00635	COG3290	protein histidine kinase activity
Thert_RS00655	COG2878	Part of a membrane complex involved in electron transport
Thert_RS00660	COG2172	sigma factor antagonist activity
Thert_RS00675	COG0741	lytic transglycosylase activity
Thert_RS00680	COG1217	gtp-binding protein TYPA
Thert_RS00685	COG0791	NLP P60 protein
Thert_RS00705	COG2707	UPF0756 membrane protein
Thert_RS00710	COG0741	lytic transglycosylase activity
Thert_RS00715	COG0237	dephospho-CoA kinase activity
Thert_RS00730	COG1595	DNA-templated transcription, initiation
Thert_RS00735	COG1376	ErfK ybiS ycfS ynhG family protein
Thert_RS00745	COG1113	amino acid transport
Thert_RS00750	COG1983	PspC domain protein
Thert_RS00755	COG1388	LysM domain
Thert_RS00755	COG3858	chitin binding
Thert_RS00760	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS00770	COG2217	Heavy metal translocating P-type atpase
Thert_RS00775	COG2217	Heavy metal translocating P-type atpase
Thert_RS00785	COG4475	Protein of unknown function (DUF436)
Thert_RS00790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Thert_RS00815	COG1362	aminopeptidase activity
Thert_RS00820	COG2197	response regulator
Thert_RS00845	COG1193	negative regulation of DNA recombination
Thert_RS00850	COG0826	peptidase U32
Thert_RS00860	COG0072	phenylalanine-tRNA ligase activity
Thert_RS00860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Thert_RS00865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Thert_RS00870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Thert_RS00875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Thert_RS00880	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Thert_RS00885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Thert_RS00890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Thert_RS00900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Thert_RS00905	COG4399	Belongs to the UPF0754 family
Thert_RS00920	COG0745	RESPONSE REGULATOR receiver
Thert_RS00935	COG0367	asparagine synthase
Thert_RS00940	COG0347	Belongs to the P(II) protein family
Thert_RS00945	COG0004	ammonium transporteR
Thert_RS00955	COG0004	ammonium transporteR
Thert_RS00975	COG0347	Belongs to the P(II) protein family
Thert_RS00980	COG0347	Belongs to the P(II) protein family
Thert_RS01000	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Thert_RS01010	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Thert_RS01015	COG0535	radical SAM domain protein
Thert_RS01015	COG1433	Dinitrogenase iron-molybdenum cofactor
Thert_RS01020	COG0535	radical SAM domain protein
Thert_RS01020	COG1433	Dinitrogenase iron-molybdenum cofactor
Thert_RS01045	COG0352	thiamine-phosphate diphosphorylase activity
Thert_RS01060	COG0352	thiamine-phosphate diphosphorylase activity
Thert_RS01060	COG0351	phosphomethylpyrimidine kinase
Thert_RS01075	COG1132	(ABC) transporter
Thert_RS01085	COG0697	spore germination
Thert_RS01090	COG5002	protein histidine kinase activity
Thert_RS01110	COG1131	(ABC) transporter
Thert_RS01120	COG1966	Carbon starvation protein
Thert_RS01125	COG3279	Response regulator of the LytR AlgR family
Thert_RS01130	COG3275	phosphorelay sensor kinase activity
Thert_RS01175	COG3973	AAA domain
Thert_RS01200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Thert_RS01205	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Thert_RS01230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Thert_RS01235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Thert_RS01250	COG0445	tRNA wobble uridine modification
Thert_RS01260	COG0395	ABC-type sugar transport system, permease component
Thert_RS01265	COG1175	transmembrane transport
Thert_RS01270	COG1653	transport
Thert_RS01275	COG1940	carbohydrate kinase activity
Thert_RS01280	COG1737	Transcriptional regulator
Thert_RS01285	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Thert_RS01300	COG1063	alcohol dehydrogenase
Thert_RS01310	COG3775	system Galactitol-specific IIC component
Thert_RS01315	COG3414	Phosphotransferase system galactitol-specific IIB component
Thert_RS01325	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Thert_RS01325	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Thert_RS01330	COG0246	Mannitol dehydrogenase
Thert_RS01340	COG3711	transcriptional antiterminator
Thert_RS01345	COG2213	PTS system mannitol-specific
Thert_RS01355	COG1609	Transcriptional regulator
Thert_RS01370	COG0366	Alpha amylase catalytic
Thert_RS01385	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Thert_RS01390	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Thert_RS01395	COG1874	Beta-galactosidase
Thert_RS01400	COG0395	ABC-type sugar transport system, permease component
Thert_RS01405	COG1175	transmembrane transport
Thert_RS01415	COG1609	Transcriptional regulator
Thert_RS01420	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
Thert_RS01425	COG2942	2-epimerase
Thert_RS01450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Thert_RS01460	COG0569	domain protein
Thert_RS01480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Thert_RS01495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Thert_RS01505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Thert_RS01515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Thert_RS01525	COG5002	protein histidine kinase activity
Thert_RS01530	COG0745	RESPONSE REGULATOR receiver
Thert_RS01555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Thert_RS01570	COG5002	protein histidine kinase activity
Thert_RS01580	COG0367	asparagine synthase
Thert_RS01580	COG0367	asparagine synthase
Thert_RS01585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Thert_RS01620	COG0390	transport system, permease component
Thert_RS01625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Thert_RS01655	COG1533	DNA photolyase activity
Thert_RS01660	COG2222	sugar isomerase
Thert_RS01665	COG1105	Belongs to the carbohydrate kinase PfkB family
Thert_RS01670	COG0191	fructose-bisphosphate aldolase activity
Thert_RS01675	COG0546	phosphoglycolate phosphatase activity
Thert_RS01685	COG4821	SIS domain
Thert_RS01710	COG3716	PTS system mannose fructose sorbose family IID component
Thert_RS01715	COG3715	PTS system
Thert_RS01720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Thert_RS01725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Thert_RS01725	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Thert_RS01730	COG1278	Cold shock
Thert_RS01735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Thert_RS01750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Thert_RS01755	COG1902	pentaerythritol trinitrate reductase activity
Thert_RS01765	COG1704	LemA family
Thert_RS01770	COG1956	GAF domain-containing protein
Thert_RS01815	COG1482	cell wall glycoprotein biosynthetic process
Thert_RS01825	COG0482	sulfurtransferase activity
Thert_RS01835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Thert_RS01840	COG2384	SAM-dependent methyltransferase
Thert_RS01855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Thert_RS01860	COG0358	DNA primase activity
Thert_RS01865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Thert_RS01870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Thert_RS01875	COG1342	Belongs to the UPF0251 family
Thert_RS01880	COG0148	phosphopyruvate hydratase activity
Thert_RS01885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Thert_RS01895	COG0126	phosphoglycerate kinase activity
Thert_RS01915	COG1254	Belongs to the acylphosphatase family
Thert_RS01920	COG0561	phosphatase activity
Thert_RS01925	COG0735	belongs to the Fur family
Thert_RS01930	COG2720	vancomycin resistance protein
Thert_RS01940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Thert_RS01945	COG1067	ATP-dependent peptidase activity
Thert_RS01975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Thert_RS01985	COG1773	rubredoxin
Thert_RS01985	COG1592	Rubrerythrin
Thert_RS02105	COG0564	pseudouridine synthase activity
Thert_RS02120	COG1074	ATP-dependent DNA helicase activity
Thert_RS02130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Thert_RS02135	COG1304	FMN binding
Thert_RS02140	COG0778	Nitroreductase
Thert_RS02150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Thert_RS02165	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Thert_RS02170	COG1511	domain protein
Thert_RS02175	COG1309	transcriptional regulator
Thert_RS02190	COG0457	Tetratricopeptide repeat
Thert_RS02190	COG0463	Glycosyl transferase, family 2
Thert_RS02200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Thert_RS02210	COG0840	transmembrane signaling receptor activity
Thert_RS02225	COG1752	Esterase of the alpha-beta hydrolase superfamily
Thert_RS02235	COG1309	transcriptional regulator
Thert_RS02280	COG0622	Phosphoesterase
Thert_RS02295	COG0860	N-Acetylmuramoyl-L-alanine amidase
Thert_RS02305	COG4608	Belongs to the ABC transporter superfamily
Thert_RS02310	COG0444	Belongs to the ABC transporter superfamily
Thert_RS02315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Thert_RS02320	COG0601	transmembrane transport
Thert_RS02325	COG4166	transmembrane transport
Thert_RS02330	COG4166	transmembrane transport
Thert_RS02335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Thert_RS02340	COG0154	amidase activity
Thert_RS02350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Thert_RS02360	COG4496	protein, YerC YecD
Thert_RS02365	COG1447	Phosphotransferase system cellobiose-specific component IIA
Thert_RS02370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Thert_RS02380	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS02390	COG3711	transcriptional antiterminator
Thert_RS02395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Thert_RS02400	COG2011	ABC-type metal ion transport system permease component
Thert_RS02410	COG2244	polysaccharide biosynthetic process
Thert_RS02430	COG1473	amidohydrolase
Thert_RS02440	COG0151	Belongs to the GarS family
Thert_RS02445	COG0138	bifunctional purine biosynthesis protein purh
Thert_RS02450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Thert_RS02455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Thert_RS02460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Thert_RS02465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Thert_RS02470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Thert_RS02475	COG2252	PERMEase
Thert_RS02565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Thert_RS02580	COG1396	sequence-specific DNA binding
Thert_RS02595	COG0519	Catalyzes the synthesis of GMP from XMP
Thert_RS02595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Thert_RS02600	COG0517	IMP dehydrogenase activity
Thert_RS02600	COG0516	GMP reductase activity
Thert_RS02635	COG1404	Belongs to the peptidase S8 family
Thert_RS02645	COG3842	ATPase activity
Thert_RS02650	COG4120	Belongs to the binding-protein-dependent transport system permease family
Thert_RS02695	COG1132	(ABC) transporter
Thert_RS02710	COG1811	Na channel or pump
Thert_RS02735	COG1914	H( )-stimulated, divalent metal cation uptake system
Thert_RS02745	COG1360	Flagellar Motor Protein
Thert_RS02755	COG0488	(ABC) transporter
Thert_RS02765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Thert_RS02770	COG0456	acetyltransferase
Thert_RS02775	COG1214	PFAM Peptidase M22, glycoprotease
Thert_RS02780	COG0802	atpase or kinase
Thert_RS02795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Thert_RS02805	COG0398	Pfam SNARE associated Golgi protein
Thert_RS02810	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Thert_RS02815	COG2183	response to ionizing radiation
Thert_RS02825	COG0653	protein targeting
Thert_RS02835	COG1827	regulation of RNA biosynthetic process
Thert_RS02860	COG1126	abc transporter atp-binding protein
Thert_RS02865	COG0765	amino acid transport
Thert_RS02870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Thert_RS02885	COG1516	flagellar protein fliS
Thert_RS02890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Thert_RS02905	COG0632	four-way junction helicase activity
Thert_RS02920	COG1083	cytidylyl-transferase
Thert_RS02925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Thert_RS02930	COG2089	acid synthase
Thert_RS02940	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Thert_RS02945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Thert_RS02950	COG1086	Polysaccharide biosynthesis protein
Thert_RS02955	COG2604	Protein of unknown function DUF115
Thert_RS02980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Thert_RS02985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Thert_RS02990	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Thert_RS03000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Thert_RS03005	COG4786	Flagellar basal body rod
Thert_RS03005	COG1256	bacterial-type flagellum assembly
Thert_RS03025	COG1040	competence protein
Thert_RS03030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Thert_RS03040	COG2199	diguanylate cyclase activity
Thert_RS03040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Thert_RS03045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Thert_RS03050	COG1592	Rubrerythrin
Thert_RS03095	COG5002	protein histidine kinase activity
Thert_RS03100	COG0745	RESPONSE REGULATOR receiver
Thert_RS03105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Thert_RS03110	COG1609	Transcriptional regulator
Thert_RS03115	COG0561	phosphatase activity
Thert_RS03120	COG2323	membrane
Thert_RS03175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Thert_RS03185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Thert_RS03190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Thert_RS03195	COG3711	transcriptional antiterminator
Thert_RS03200	COG0840	transmembrane signaling receptor activity
Thert_RS03215	COG0295	cytidine deaminase activity
Thert_RS03220	COG2188	Transcriptional regulator
Thert_RS03225	COG1079	Belongs to the binding-protein-dependent transport system permease family
Thert_RS03230	COG4603	Belongs to the binding-protein-dependent transport system permease family
Thert_RS03235	COG3845	ABC transporter
Thert_RS03240	COG1744	ABC transporter substrate-binding protein PnrA-like
Thert_RS03245	COG3404	Formiminotransferase-cyclodeaminase
Thert_RS03295	COG0484	heat shock protein binding
Thert_RS03325	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Thert_RS03330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Thert_RS03355	COG1797	cobyrinic acid a,c-diamide synthase activity
Thert_RS03360	COG1120	ATPase activity
Thert_RS03365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Thert_RS03370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Thert_RS03385	COG5464	transposase or invertase
Thert_RS03415	COG1131	(ABC) transporter
Thert_RS03455	COG0531	amino acid
Thert_RS03460	COG0116	Belongs to the methyltransferase superfamily
Thert_RS03470	COG2226	methyltransferase
Thert_RS03480	COG1522	sequence-specific DNA binding
Thert_RS03485	COG0436	Aminotransferase
Thert_RS03505	COG0671	phosphoesterase, PA-phosphatase related
Thert_RS03515	COG0803	Belongs to the bacterial solute-binding protein 9 family
Thert_RS03520	COG1121	(ABC) transporter
Thert_RS03525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Thert_RS03540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Thert_RS03550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Thert_RS03555	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS03580	COG1609	Transcriptional regulator
Thert_RS03600	COG0730	response to heat
Thert_RS03605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Thert_RS03620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Thert_RS03625	COG2971	BadF BadG BcrA BcrD
Thert_RS03630	COG1472	Belongs to the glycosyl hydrolase 3 family
Thert_RS03640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Thert_RS03645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Thert_RS03675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Thert_RS03680	COG1447	Phosphotransferase system cellobiose-specific component IIA
Thert_RS03690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Thert_RS03690	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Thert_RS03695	COG0531	amino acid
Thert_RS03700	COG4166	transmembrane transport
Thert_RS03730	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Thert_RS03735	COG0495	leucyl-tRNA aminoacylation
Thert_RS03755	COG0436	Aminotransferase
Thert_RS03765	COG4214	carbohydrate transport
Thert_RS03775	COG4213	ABC transporter substrate-binding protein
Thert_RS03780	COG4213	ABC transporter substrate-binding protein
Thert_RS03785	COG4753	response regulator
Thert_RS03785	COG2207	Transcriptional regulator
Thert_RS03790	COG3275	phosphorelay sensor kinase activity
Thert_RS03805	COG4211	Belongs to the binding-protein-dependent transport system permease family
Thert_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
Thert_RS03830	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Thert_RS03835	COG1609	Transcriptional regulator
Thert_RS03850	COG0246	Mannitol dehydrogenase
Thert_RS03855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Thert_RS03860	COG1070	Carbohydrate kinase
Thert_RS03865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Thert_RS03875	COG1349	DNA-binding transcription factor activity
Thert_RS03885	COG0534	Mate efflux family protein
Thert_RS03890	COG2721	sulfolactate sulfo-lyase activity
Thert_RS03895	COG0246	Mannitol dehydrogenase
Thert_RS03900	COG1486	melibiose metabolic process
Thert_RS03910	COG0395	ABC-type sugar transport system, permease component
Thert_RS03915	COG1175	transmembrane transport
Thert_RS03925	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Thert_RS03930	COG1609	Transcriptional regulator
Thert_RS03935	COG1904	glucuronate isomerase
Thert_RS03940	COG0791	NLP P60 protein
Thert_RS03940	COG1388	LysM domain
Thert_RS03950	COG0493	'glutamate synthase
Thert_RS03965	COG0039	L-malate dehydrogenase activity
Thert_RS03995	COG0586	Pfam SNARE associated Golgi protein
Thert_RS04000	COG0297	glycogen (starch) synthase activity
Thert_RS04010	COG1085	galactose-1-phosphate uridylyltransferase
Thert_RS04060	COG0395	ABC-type sugar transport system, permease component
Thert_RS04095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Thert_RS04100	COG3958	Transketolase
Thert_RS04105	COG3959	Transketolase, thiamine diphosphate binding domain
Thert_RS04115	COG1609	Transcriptional regulator
Thert_RS04120	COG2723	6-phospho-beta-galactosidase activity
Thert_RS04125	COG0730	response to heat
Thert_RS04130	COG0641	radical SAM
Thert_RS04135	COG3119	arylsulfatase activity
Thert_RS04145	COG3119	arylsulfatase activity
Thert_RS04150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Thert_RS04160	COG1447	Phosphotransferase system cellobiose-specific component IIA
Thert_RS04165	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Thert_RS04165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Thert_RS04180	COG4716	Myosin-crossreactive antigen
Thert_RS04190	COG3875	lactate racemase activity
Thert_RS04195	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Thert_RS04200	COG0179	Fumarylacetoacetate (FAA) hydrolase
Thert_RS04205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Thert_RS04230	COG0534	Mate efflux family protein
Thert_RS04235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Thert_RS04245	COG2217	Heavy metal translocating P-type atpase
Thert_RS04255	COG1309	transcriptional regulator
Thert_RS04270	COG1131	(ABC) transporter
Thert_RS04280	COG0864	Transcriptional regulator
Thert_RS04285	COG0310	cobalt ion transport
Thert_RS04290	COG0310	cobalt ion transport
Thert_RS04300	COG1122	ATPase activity
Thert_RS04320	COG1595	DNA-templated transcription, initiation
Thert_RS04330	COG3958	Transketolase
Thert_RS04335	COG3959	Transketolase, thiamine diphosphate binding domain
Thert_RS04350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS04355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Thert_RS04365	COG1609	Transcriptional regulator
Thert_RS04370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Thert_RS04380	COG1472	Belongs to the glycosyl hydrolase 3 family
Thert_RS04385	COG1070	Carbohydrate kinase
Thert_RS04390	COG2115	Belongs to the xylose isomerase family
Thert_RS04400	COG2267	carboxylic ester hydrolase activity
Thert_RS04410	COG0583	DNA-binding transcription factor activity
Thert_RS04425	COG4632	Exopolysaccharide biosynthesis protein
Thert_RS04425	COG5434	Belongs to the glycosyl hydrolase 28 family
Thert_RS04430	COG1979	alcohol dehydrogenase
Thert_RS04440	COG0463	Glycosyl transferase, family 2
Thert_RS04440	COG0457	Tetratricopeptide repeat
Thert_RS04445	COG0840	transmembrane signaling receptor activity
Thert_RS04450	COG1496	oxidoreductase activity
Thert_RS04465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Thert_RS04470	COG1132	(ABC) transporter
Thert_RS04475	COG1132	(ABC) transporter
Thert_RS04490	COG4786	Flagellar basal body rod
Thert_RS04500	COG1609	Transcriptional regulator
Thert_RS04510	COG2385	sporulation resulting in formation of a cellular spore
Thert_RS04555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Thert_RS04570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Thert_RS04580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Thert_RS04590	COG3732	PTS system glucitol sorbitol-specific
Thert_RS04615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Thert_RS04620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Thert_RS04635	COG0698	ribose 5-phosphate isomerase
Thert_RS04640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Thert_RS04645	COG0009	L-threonylcarbamoyladenylate synthase
Thert_RS04660	COG2890	protein-(glutamine-N5) methyltransferase activity
Thert_RS04665	COG3872	metal-dependent enzyme
Thert_RS04675	COG0254	rRNA binding
Thert_RS04680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Thert_RS04695	COG0745	RESPONSE REGULATOR receiver
Thert_RS04700	COG2247	cell wall binding repeat
Thert_RS04700	COG0860	N-Acetylmuramoyl-L-alanine amidase
Thert_RS04720	COG1132	(ABC) transporter
Thert_RS04725	COG1132	(ABC) transporter
Thert_RS04745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS04745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS04745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS04750	COG1105	Belongs to the carbohydrate kinase PfkB family
Thert_RS04755	COG1349	DNA-binding transcription factor activity
Thert_RS04780	COG1216	Glycosyl transferase, family 2
Thert_RS04790	COG0463	Glycosyl transferase, family 2
Thert_RS04795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Thert_RS04820	COG2770	Histidine kinase
Thert_RS04820	COG2205	protein histidine kinase activity
Thert_RS04825	COG0745	RESPONSE REGULATOR receiver
Thert_RS04830	COG2373	Large extracellular alpha-helical protein
Thert_RS04860	COG0504	CTP synthase activity
Thert_RS04865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Thert_RS04880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Thert_RS04885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Thert_RS04890	COG1929	Belongs to the glycerate kinase type-1 family
Thert_RS04895	COG0793	Belongs to the peptidase S41A family
Thert_RS04895	COG3409	Peptidoglycan-binding domain 1 protein
Thert_RS04900	COG0083	homoserine kinase activity
Thert_RS04905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Thert_RS04910	COG0460	homoserine dehydrogenase
Thert_RS04925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Thert_RS04930	COG0674	pyruvate-flavodoxin oxidoreductase activity
Thert_RS04930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Thert_RS04935	COG1013	pyruvate-flavodoxin oxidoreductase activity
Thert_RS04940	COG1132	(ABC) transporter
Thert_RS04950	COG1846	Transcriptional regulator
Thert_RS04975	COG1732	Glycine betaine
Thert_RS04980	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Thert_RS04985	COG1518	maintenance of DNA repeat elements
Thert_RS05040	COG1337	RAMP superfamily
Thert_RS05075	COG0822	iron-sulfur transferase activity
Thert_RS05080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Thert_RS05085	COG0719	Fe-S assembly protein
Thert_RS05090	COG0719	Fe-S assembly protein
Thert_RS05130	COG1012	belongs to the aldehyde dehydrogenase family
Thert_RS05130	COG1454	alcohol dehydrogenase
Thert_RS05140	COG0667	Aldo Keto reductase
Thert_RS05160	COG1924	4 iron, 4 sulfur cluster binding
Thert_RS05185	COG1131	(ABC) transporter
Thert_RS05240	COG2199	diguanylate cyclase activity
Thert_RS05240	COG2203	Gaf domain
Thert_RS05245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Thert_RS05255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Thert_RS05260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Thert_RS05280	COG5002	protein histidine kinase activity
Thert_RS05285	COG0745	RESPONSE REGULATOR receiver
Thert_RS05295	COG0739	heme binding
Thert_RS05390	COG0358	DNA primase activity
Thert_RS05415	COG2045	Belongs to the ComB family
Thert_RS05425	COG5564	TIM-barrel signal transduction protein
Thert_RS05435	COG2204	response regulator
Thert_RS05435	COG5564	TIM-barrel signal transduction protein
Thert_RS05445	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS05455	COG0732	type I restriction modification DNA specificity domain
Thert_RS05500	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Thert_RS05525	COG3850	Histidine kinase
Thert_RS05525	COG5002	protein histidine kinase activity
Thert_RS05530	COG0745	RESPONSE REGULATOR receiver
Thert_RS05540	COG2239	Acts as a magnesium transporter
Thert_RS05550	COG0305	Participates in initiation and elongation during chromosome replication
Thert_RS05560	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Thert_RS05565	COG4241	membrane
Thert_RS05580	COG0629	single-stranded DNA binding
Thert_RS05585	COG0360	Binds together with S18 to 16S ribosomal RNA
Thert_RS05590	COG4481	Protein conserved in bacteria
Thert_RS05595	COG0668	transmembrane transport
Thert_RS05610	COG0189	ligase activity
Thert_RS05610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Thert_RS05620	COG1597	lipid kinase activity
Thert_RS05630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Thert_RS05635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Thert_RS05640	COG1475	DNA binding
Thert_RS05645	COG1192	Involved in chromosome partitioning
Thert_RS05650	COG1475	DNA binding
Thert_RS05660	COG0357	Ribosomal RNA small subunit methyltransferase G
Thert_RS05670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Thert_RS05675	COG1847	R3H domain protein
Thert_RS05680	COG0706	membrane insertase activity
Thert_RS05705	COG0592	DNA-directed DNA polymerase activity
Thert_RS05710	COG2501	S4 domain
Thert_RS05735	COG0187	DNA topoisomerase II activity
Thert_RS05740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Thert_RS05755	COG0440	acetolactate synthase activity
Thert_RS05760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Thert_RS05765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Thert_RS05775	COG0066	3-isopropylmalate dehydratase activity
Thert_RS05780	COG0473	3-isopropylmalate dehydrogenase activity
Thert_RS05785	COG0129	dihydroxy-acid dehydratase activity
Thert_RS05790	COG0028	Belongs to the TPP enzyme family
Thert_RS05850	COG1316	TRANSCRIPTIONal
Thert_RS05855	COG1615	UPF0182 protein
Thert_RS05885	COG0641	radical SAM
Thert_RS05925	COG0358	DNA primase activity
Thert_RS05945	COG0582	viral genome integration into host DNA
Thert_RS05955	COG0590	tRNA wobble adenosine to inosine editing
Thert_RS05975	COG2199	diguanylate cyclase activity
Thert_RS05975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Thert_RS05980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Thert_RS05990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Thert_RS06000	COG0460	homoserine dehydrogenase
Thert_RS06005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Thert_RS06015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Thert_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
Thert_RS06070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Thert_RS06085	COG1187	pseudouridine synthase activity
Thert_RS06090	COG1882	Formate acetyltransferase
Thert_RS06095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Thert_RS06100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Thert_RS06115	COG1573	uracil-dna glycosylase
Thert_RS06135	COG1940	carbohydrate kinase activity
Thert_RS06140	COG0519	Catalyzes the synthesis of GMP from XMP
Thert_RS06150	COG1982	Orn Lys Arg decarboxylase major
Thert_RS06160	COG3870	Protein conserved in bacteria
Thert_RS06175	COG1774	PSP1 C-terminal conserved region
Thert_RS06185	COG0730	response to heat
Thert_RS06195	COG2235	arginine
Thert_RS06200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Thert_RS06205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Thert_RS06210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Thert_RS06215	COG2002	toxin-antitoxin pair type II binding
Thert_RS06220	COG2715	membrane protein required for spore maturation
Thert_RS06225	COG0700	Nucleoside recognition
Thert_RS06230	COG0617	tRNA 3'-terminal CCA addition
Thert_RS06235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Thert_RS06235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Thert_RS06260	COG3063	Type IV pilus biogenesis stability protein PilW
Thert_RS06275	COG0084	hydrolase, TatD family'
Thert_RS06285	COG3583	domain protein
Thert_RS06285	COG3584	3D domain protein
Thert_RS06290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Thert_RS06310	COG0489	protein tyrosine kinase activity
Thert_RS06330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Thert_RS06330	COG2111	Na H antiporter
Thert_RS06340	COG3260	NADH ubiquinone oxidoreductase 20
Thert_RS06355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Thert_RS06360	COG0375	protein maturation
Thert_RS06370	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Thert_RS06375	COG0298	carbon dioxide binding
Thert_RS06380	COG0409	Hydrogenase expression formation protein
Thert_RS06390	COG3773	Cell wall hydrolase
Thert_RS06425	COG1131	(ABC) transporter
Thert_RS06435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Thert_RS06540	COG0789	Transcriptional regulator
Thert_RS06545	COG1664	Polymer-forming cytoskeletal
Thert_RS06555	COG0071	Belongs to the small heat shock protein (HSP20) family
Thert_RS06565	COG1609	Transcriptional regulator
Thert_RS06570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Thert_RS06575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Thert_RS06585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Thert_RS06590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Thert_RS06600	COG5002	protein histidine kinase activity
Thert_RS06600	COG3850	Histidine kinase
Thert_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Thert_RS06620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Thert_RS06625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Thert_RS06635	COG2002	toxin-antitoxin pair type II binding
Thert_RS06645	COG4466	Protein conserved in bacteria
Thert_RS06655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Thert_RS06660	COG1802	Transcriptional regulator
Thert_RS06675	COG0697	spore germination
Thert_RS06680	COG0531	amino acid
Thert_RS06695	COG1982	Orn Lys Arg decarboxylase major
Thert_RS06705	COG2959	enzyme of heme biosynthesis
Thert_RS06725	COG0018	arginyl-trna synthetase
Thert_RS06730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Thert_RS06735	COG1131	(ABC) transporter
Thert_RS06740	COG0167	dihydroorotate dehydrogenase activity
Thert_RS06745	COG0531	amino acid
Thert_RS06755	COG0667	Aldo Keto reductase
Thert_RS06765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Thert_RS06770	COG3859	Proton-coupled thiamine transporter YuaJ
Thert_RS06775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Thert_RS06780	COG0671	phosphoesterase, PA-phosphatase related
Thert_RS06810	COG4632	Exopolysaccharide biosynthesis protein
Thert_RS06810	COG5434	Belongs to the glycosyl hydrolase 28 family
Thert_RS06815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Thert_RS06845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Thert_RS06850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Thert_RS06860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Thert_RS06865	COG0505	Belongs to the CarA family
Thert_RS06895	COG0586	Pfam SNARE associated Golgi protein
Thert_RS06910	COG2033	superoxide reductase activity
Thert_RS06915	COG1027	Aspartate ammonia-lyase
Thert_RS06935	COG3956	TIGRFAM MazG family protein
Thert_RS06945	COG0776	regulation of translation
Thert_RS06950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Thert_RS06955	COG2385	sporulation resulting in formation of a cellular spore
Thert_RS06990	COG1098	S1 RNA binding domain
Thert_RS06995	COG0248	Ppx GppA phosphatase
Thert_RS06995	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Thert_RS07050	COG1396	sequence-specific DNA binding
Thert_RS07120	COG1349	DNA-binding transcription factor activity
Thert_RS07130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Thert_RS07150	COG3959	Transketolase, thiamine diphosphate binding domain
Thert_RS07155	COG3958	Transketolase
Thert_RS07165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Thert_RS07170	COG0698	ribose 5-phosphate isomerase
Thert_RS07175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Thert_RS07230	COG3464	Transposase
Thert_RS07245	COG2267	carboxylic ester hydrolase activity
Thert_RS07290	COG0653	protein targeting
Thert_RS07305	COG0860	N-Acetylmuramoyl-L-alanine amidase
Thert_RS07315	COG2233	PERMEase
Thert_RS07330	COG1131	(ABC) transporter
Thert_RS07340	COG1309	transcriptional regulator
Thert_RS07345	COG1013	pyruvate-flavodoxin oxidoreductase activity
Thert_RS07345	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Thert_RS07345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Thert_RS07345	COG0674	pyruvate-flavodoxin oxidoreductase activity
Thert_RS07375	COG1131	(ABC) transporter
Thert_RS07385	COG1595	DNA-templated transcription, initiation
Thert_RS07405	COG3830	Belongs to the UPF0237 family
Thert_RS07415	COG2226	methyltransferase
Thert_RS07440	COG2226	methyltransferase
Thert_RS07450	COG2208	phosphoserine phosphatase activity
Thert_RS07465	COG0037	tRNA processing
Thert_RS07470	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Thert_RS07490	COG3852	Histidine kinase
Thert_RS07505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Thert_RS07510	COG4770	biotin carboxylase activity
Thert_RS07515	COG4684	Psort location CytoplasmicMembrane, score
Thert_RS07530	COG0697	spore germination
Thert_RS07555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Thert_RS07555	COG5322	oxidoreductase activity
Thert_RS07565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Thert_RS07580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Thert_RS07585	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Thert_RS07590	COG0720	synthase
Thert_RS07600	COG4224	UPF0291 protein
Thert_RS07620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Thert_RS07625	COG2199	diguanylate cyclase activity
Thert_RS07625	COG2203	Gaf domain
Thert_RS07630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS07630	COG3711	transcriptional antiterminator
Thert_RS07635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS07635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS07635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS07640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS07640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS07640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS07645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Thert_RS07650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Thert_RS07655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Thert_RS07660	COG0281	malic enzyme
Thert_RS07675	COG3880	PFAM UvrB UvrC protein
Thert_RS07680	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Thert_RS07685	COG0542	response to heat
Thert_RS07690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Thert_RS07700	COG4956	integral membrane protein (PIN domain superfamily)
Thert_RS07705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Thert_RS07715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Thert_RS07730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Thert_RS07735	COG1045	serine acetyltransferase
Thert_RS07750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Thert_RS07755	COG3688	RNA-binding protein containing a PIN domain
Thert_RS07760	COG1595	DNA-templated transcription, initiation
Thert_RS07770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Thert_RS07775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Thert_RS07780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Thert_RS07785	COG0250	Participates in transcription elongation, termination and antitermination
Thert_RS07805	COG0222	ribosome binding
Thert_RS07815	COG0085	RNA polymerase activity
Thert_RS07820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Thert_RS07825	COG1358	cellular component organization or biogenesis
Thert_RS07830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Thert_RS07835	COG0049	tRNA binding
Thert_RS07845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Thert_RS07855	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Thert_RS07880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Thert_RS07885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Thert_RS07890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Thert_RS07920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Thert_RS07930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Thert_RS07945	COG1841	ribosomal large subunit assembly
Thert_RS07955	COG0201	protein transport
Thert_RS07975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Thert_RS07980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Thert_RS07990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Thert_RS08010	COG1122	ATPase activity
Thert_RS08015	COG1122	ATPase activity
Thert_RS08020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Thert_RS08030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Thert_RS08100	COG3959	Transketolase, thiamine diphosphate binding domain
Thert_RS08105	COG3958	Transketolase
Thert_RS08110	COG0698	ribose 5-phosphate isomerase
Thert_RS08115	COG0613	PHP domain protein
Thert_RS08125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Thert_RS08140	COG1012	belongs to the aldehyde dehydrogenase family
Thert_RS08145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Thert_RS08150	COG1070	Carbohydrate kinase
Thert_RS08155	COG2197	response regulator
Thert_RS08210	COG4869	propanediol catabolic process
Thert_RS08220	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Thert_RS08225	COG2096	Adenosyltransferase
Thert_RS08230	COG1012	belongs to the aldehyde dehydrogenase family
Thert_RS08235	COG1454	alcohol dehydrogenase
Thert_RS08240	COG1737	Transcriptional regulator
Thert_RS08250	COG1486	melibiose metabolic process
Thert_RS08255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Thert_RS08255	COG1263	PTS System
Thert_RS08255	COG2190	(PTS) system
Thert_RS08260	COG2190	(PTS) system
Thert_RS08270	COG1929	Belongs to the glycerate kinase type-1 family
Thert_RS08290	COG0358	DNA primase activity
Thert_RS08340	COG0582	viral genome integration into host DNA
Thert_RS08355	COG1136	(ABC) transporter
Thert_RS08360	COG0577	efflux transmembrane transporter activity
Thert_RS08360	COG1136	(ABC) transporter
Thert_RS08365	COG1454	alcohol dehydrogenase
Thert_RS08410	COG0860	N-Acetylmuramoyl-L-alanine amidase
Thert_RS08415	COG0714	Associated with various cellular activities
Thert_RS08420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Thert_RS08425	COG1305	Transglutaminase-like
Thert_RS08435	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Thert_RS08475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Thert_RS08485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Thert_RS08590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Thert_RS08620	COG1201	RNA secondary structure unwinding
Thert_RS08640	COG1397	ADP-ribosylglycohydrolase
Thert_RS08680	COG4974	Belongs to the 'phage' integrase family
Thert_RS08790	COG0515	serine threonine protein kinase
Thert_RS08790	COG2815	serine threonine protein kinase
Thert_RS08805	COG1397	ADP-ribosylglycohydrolase
Thert_RS08815	COG1396	sequence-specific DNA binding
Thert_RS08850	COG1733	regulation of RNA biosynthetic process
Thert_RS08905	COG0561	phosphatase activity
Thert_RS08910	COG2703	oxygen carrier activity
Thert_RS08920	COG3973	AAA domain
Thert_RS08925	COG0432	Pfam Uncharacterised protein family UPF0047
Thert_RS08940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Thert_RS08940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Thert_RS08950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Thert_RS08960	COG2337	Toxic component of a toxin-antitoxin (TA) module
Thert_RS08980	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Thert_RS08985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Thert_RS08995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Thert_RS09000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Thert_RS09015	COG1773	rubredoxin
Thert_RS09020	COG0673	inositol 2-dehydrogenase activity
Thert_RS09040	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Thert_RS09040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Thert_RS09045	COG3459	Glycosyltransferase 36 associated
Thert_RS09050	COG1725	Transcriptional regulator
Thert_RS09060	COG4377	Putative membrane peptidase family (DUF2324)
Thert_RS09065	COG0330	HflC and HflK could
Thert_RS09075	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Thert_RS09085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Thert_RS09095	COG0131	Imidazoleglycerol-phosphate dehydratase
Thert_RS09100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Thert_RS09115	COG0140	phosphoribosyl-ATP diphosphatase activity
Thert_RS09115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Thert_RS09120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Thert_RS09145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Thert_RS09170	COG0640	Transcriptional regulator
Thert_RS09190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Thert_RS09195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Thert_RS09210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Thert_RS09215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Thert_RS09220	COG0579	oxidoreductase
Thert_RS09225	COG0446	pyridine nucleotide-disulphide oxidoreductase
Thert_RS09235	COG3290	protein histidine kinase activity
Thert_RS09235	COG3829	transcription factor binding
Thert_RS09240	COG2376	Dihydroxyacetone kinase
Thert_RS09245	COG1461	Dihydroxyacetone kinase
Thert_RS09250	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Thert_RS09260	COG0443	Heat shock 70 kDa protein
Thert_RS09295	COG0849	cell division
Thert_RS09320	COG1131	(ABC) transporter
Thert_RS09350	COG3842	ATPase activity
Thert_RS09365	COG0437	4 iron, 4 sulfur cluster binding
Thert_RS09370	COG0069	glutamate synthase activity
Thert_RS09380	COG3835	regulator
Thert_RS09385	COG2884	Cell division ATP-binding protein ftsE
Thert_RS09390	COG2177	Part of the ABC transporter FtsEX involved in
Thert_RS09395	COG0739	heme binding
Thert_RS09400	COG0793	Belongs to the peptidase S41A family
Thert_RS09405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Thert_RS09410	COG2045	Belongs to the ComB family
Thert_RS09415	COG0556	nucleotide-excision repair
Thert_RS09425	COG1716	ATPase activity
Thert_RS09435	COG0768	penicillin binding
Thert_RS09445	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Thert_RS09445	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Thert_RS09455	COG2190	(PTS) system
Thert_RS09455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Thert_RS09455	COG1263	PTS System
Thert_RS09460	COG2723	6-phospho-beta-galactosidase activity
Thert_RS09475	COG1940	carbohydrate kinase activity
Thert_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
Thert_RS09490	COG0673	inositol 2-dehydrogenase activity
Thert_RS09505	COG0673	inositol 2-dehydrogenase activity
Thert_RS09510	COG3250	beta-galactosidase activity
Thert_RS09515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Thert_RS09515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Thert_RS09520	COG1447	Phosphotransferase system cellobiose-specific component IIA
Thert_RS09525	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Thert_RS09545	COG2723	6-phospho-beta-galactosidase activity
Thert_RS09555	COG4209	transmembrane transport
Thert_RS09560	COG0395	ABC-type sugar transport system, permease component
Thert_RS09580	COG1874	Beta-galactosidase
Thert_RS09585	COG1501	Belongs to the glycosyl hydrolase 31 family
Thert_RS09590	COG3534	alpha-L-arabinofuranosidase
Thert_RS09600	COG4209	transmembrane transport
Thert_RS09605	COG0395	ABC-type sugar transport system, permease component
Thert_RS09630	COG2160	L-arabinose isomerase activity
Thert_RS09635	COG1069	ribulokinase activity
Thert_RS09640	COG0235	Class ii aldolase
Thert_RS09650	COG1609	Transcriptional regulator
Thert_RS09655	COG0371	Dehydrogenase
Thert_RS09680	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Thert_RS09685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Thert_RS09690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Thert_RS09695	COG1940	carbohydrate kinase activity
Thert_RS09700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Thert_RS09730	COG1477	protein flavinylation
Thert_RS09740	COG0768	penicillin binding
Thert_RS09745	COG1793	dna ligase
Thert_RS09750	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Thert_RS09755	COG0791	NLP P60 protein
Thert_RS09755	COG1388	LysM domain
Thert_RS09760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Thert_RS09775	COG2755	lipolytic protein G-D-S-L family
Thert_RS09775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Thert_RS09780	COG0531	amino acid
Thert_RS09785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Thert_RS09805	COG2608	mercury ion transmembrane transporter activity
Thert_RS09820	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS09845	COG2211	Major facilitator Superfamily
Thert_RS09865	COG1609	Transcriptional regulator
Thert_RS09875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Thert_RS09880	COG4209	transmembrane transport
Thert_RS09885	COG0395	ABC-type sugar transport system, permease component
Thert_RS09895	COG1621	beta-fructofuranosidase activity
Thert_RS09920	COG1796	DNA polymerase
Thert_RS09920	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Thert_RS09925	COG2873	o-acetylhomoserine
Thert_RS09935	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Thert_RS09945	COG4942	peptidase
Thert_RS09965	COG1914	H( )-stimulated, divalent metal cation uptake system
Thert_RS09975	COG2226	methyltransferase
Thert_RS09985	COG0785	Cytochrome C biogenesis protein
Thert_RS10005	COG3852	Histidine kinase
Thert_RS10010	COG2204	response regulator
Thert_RS10030	COG2217	Heavy metal translocating P-type atpase
Thert_RS10035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Thert_RS10040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Thert_RS10045	COG1660	Displays ATPase and GTPase activities
Thert_RS10055	COG1653	transport
Thert_RS10075	COG1175	transmembrane transport
Thert_RS10080	COG3833	ABC-type maltose transport systems, permease component
Thert_RS10095	COG1426	Protein conserved in bacteria
Thert_RS10100	COG0366	Alpha amylase catalytic
Thert_RS10110	COG1481	regulation of sporulation
Thert_RS10115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Thert_RS10120	COG4109	DRTGG domain
Thert_RS10155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Thert_RS10190	COG1131	(ABC) transporter
Thert_RS10305	COG1802	Transcriptional regulator
Thert_RS10305	COG4626	Terminase
Thert_RS10310	COG4695	Portal protein
Thert_RS10315	COG0740	serine-type endopeptidase activity
Thert_RS10380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Thert_RS10385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Thert_RS10390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Thert_RS10410	COG1846	Transcriptional regulator
Thert_RS10430	COG5632	N-Acetylmuramoyl-L-alanine amidase
Thert_RS10430	COG3409	Peptidoglycan-binding domain 1 protein
Thert_RS10450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Thert_RS10515	COG0745	RESPONSE REGULATOR receiver
Thert_RS10520	COG5002	protein histidine kinase activity
Thert_RS10565	COG1309	transcriptional regulator
Thert_RS10575	COG0778	Nitroreductase
Thert_RS10600	COG1199	ATP-dependent helicase activity
Thert_RS10610	COG3064	Membrane
Thert_RS10610	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Thert_RS10610	COG1073	alpha beta
Thert_RS10615	COG2195	Cleaves the N-terminal amino acid of tripeptides
Thert_RS10620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Thert_RS10625	COG0778	Nitroreductase
Thert_RS10650	COG3275	phosphorelay sensor kinase activity
Thert_RS10655	COG3279	Response regulator of the LytR AlgR family
Thert_RS10660	COG1966	Carbon starvation protein
Thert_RS10665	COG4656	Part of a membrane complex involved in electron transport
Thert_RS10670	COG4658	electron transport chain
Thert_RS10675	COG4659	FMN binding
Thert_RS10680	COG4660	Part of a membrane complex involved in electron transport
Thert_RS10685	COG4657	Part of a membrane complex involved in electron transport
Thert_RS10690	COG1245	4Fe-4S binding domain
Thert_RS10690	COG2878	Part of a membrane complex involved in electron transport
Thert_RS10705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Thert_RS10705	COG0646	methionine synthase
Thert_RS10710	COG0646	methionine synthase
Thert_RS10710	COG1410	methionine synthase
Thert_RS10715	COG3546	catalase activity
Thert_RS10735	COG1598	PFAM Uncharacterised protein family UPF0150
Thert_RS10740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Thert_RS10760	COG5002	protein histidine kinase activity
Thert_RS10820	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Thert_RS10855	COG0789	Transcriptional regulator
Thert_RS10875	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Thert_RS10880	COG1234	tRNA 3'-trailer cleavage
Thert_RS10895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Thert_RS10905	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Thert_RS10915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Thert_RS10920	COG0569	domain protein
Thert_RS10925	COG0356	it plays a direct role in the translocation of protons across the membrane
Thert_RS10930	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Thert_RS10935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Thert_RS10940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Thert_RS10945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Thert_RS10950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Thert_RS10955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Thert_RS10960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Thert_RS10975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Thert_RS10975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Thert_RS10980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Thert_RS10985	COG1116	anion transmembrane transporter activity
Thert_RS10990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Thert_RS11000	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Thert_RS11045	COG1215	transferase activity, transferring glycosyl groups
Thert_RS11050	COG0438	transferase activity, transferring glycosyl groups
Thert_RS11055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Thert_RS11065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Thert_RS11145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Thert_RS11165	COG1078	dGTPase activity
Thert_RS11170	COG3465	dGTPase activity
Thert_RS11260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Thert_RS11285	COG1312	Catalyzes the dehydration of D-mannonate
Thert_RS11290	COG4209	transmembrane transport
Thert_RS11295	COG0395	ABC-type sugar transport system, permease component
Thert_RS11315	COG0673	inositol 2-dehydrogenase activity
Thert_RS11335	COG3458	cephalosporin-C deacetylase activity
Thert_RS11340	COG4753	response regulator
Thert_RS11340	COG2207	Transcriptional regulator
Thert_RS11340	COG4753	response regulator
Thert_RS11340	COG2207	Transcriptional regulator
Thert_RS11345	COG3275	phosphorelay sensor kinase activity
Thert_RS11355	COG2182	Extracellular solute-binding protein
Thert_RS11360	COG1653	transport
Thert_RS11365	COG1175	transmembrane transport
Thert_RS11370	COG0395	ABC-type sugar transport system, permease component
Thert_RS11410	COG1942	4-Oxalocrotonate Tautomerase
Thert_RS11450	COG3944	biosynthesis protein
Thert_RS11455	COG0489	protein tyrosine kinase activity
Thert_RS11460	COG4464	protein tyrosine phosphatase activity
Thert_RS11465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Thert_RS11480	COG3949	Membrane
Thert_RS11490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Thert_RS11505	COG2814	Major facilitator Superfamily
Thert_RS11520	COG0426	domain, Protein
Thert_RS11525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Thert_RS11530	COG0671	phosphoesterase, PA-phosphatase related
Thert_RS11540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Thert_RS11545	COG1606	tRNA processing
Thert_RS11550	COG1691	(AIR) carboxylase
Thert_RS11555	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Thert_RS11560	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Thert_RS11565	COG1268	BioY protein
Thert_RS11570	COG0525	valine-tRNA ligase activity
Thert_RS11580	COG0285	dihydrofolate synthase activity
Thert_RS11615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Thert_RS11625	COG1609	Transcriptional regulator
Thert_RS11635	COG0395	ABC-type sugar transport system, permease component
Thert_RS11645	COG2182	Extracellular solute-binding protein
Thert_RS11665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Thert_RS11690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Thert_RS11700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Thert_RS11730	COG1181	Belongs to the D-alanine--D-alanine ligase family
Thert_RS11755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Thert_RS11760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Thert_RS11775	COG3858	chitin binding
Thert_RS11785	COG0739	heme binding
Thert_RS11790	COG0438	transferase activity, transferring glycosyl groups
Thert_RS11820	COG0438	transferase activity, transferring glycosyl groups
Thert_RS11825	COG1937	Protein conserved in bacteria
Thert_RS11835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Thert_RS11865	COG0012	GTP binding
Thert_RS11875	COG0612	Peptidase, M16
Thert_RS11880	COG0612	Peptidase, M16
Thert_RS11900	COG0768	penicillin binding
Thert_RS11905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Thert_RS11910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Thert_RS11915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Thert_RS11925	COG0772	Belongs to the SEDS family
Thert_RS11935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Thert_RS11940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Thert_RS11950	COG3856	small basic protein
Thert_RS11955	COG0849	cell division
Thert_RS11960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Thert_RS11970	COG1191	sigma factor activity
Thert_RS11975	COG1191	sigma factor activity
Thert_RS11980	COG1873	PFAM PRC-barrel domain
Thert_RS11990	COG0745	RESPONSE REGULATOR receiver
Thert_RS11995	COG5002	protein histidine kinase activity
Thert_RS12005	COG0573	inorganic phosphate transmembrane transporter activity
Thert_RS12010	COG0581	inorganic phosphate transmembrane transporter activity
Thert_RS12015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Thert_RS12020	COG0704	Plays a role in the regulation of phosphate uptake
Thert_RS12065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Thert_RS12075	COG2186	Transcriptional regulator
Thert_RS12080	COG1620	l-lactate permease
Thert_RS12085	COG2086	electron transfer activity
Thert_RS12090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Thert_RS12095	COG0277	FAD linked oxidase domain protein
Thert_RS12100	COG3875	lactate racemase activity
Thert_RS12110	COG1024	Enoyl-CoA hydratase
Thert_RS12115	COG1960	acyl-CoA dehydrogenase activity
Thert_RS12120	COG2086	electron transfer activity
Thert_RS12125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Thert_RS12130	COG1250	3-hydroxyacyl-CoA dehydrogenase
Thert_RS12135	COG0183	Belongs to the thiolase family
Thert_RS12140	COG0427	acetyl-CoA hydrolase
Thert_RS12145	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Thert_RS12155	COG3858	chitin binding
Thert_RS12160	COG4086	secreted protein
Thert_RS12170	COG1032	radical SAM domain protein
Thert_RS12175	COG0584	glycerophosphoryl diester phosphodiesterase
Thert_RS12190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Thert_RS12195	COG1968	undecaprenyl-diphosphatase activity
Thert_RS12210	COG3069	C4-dicarboxylate transmembrane transporter activity
Thert_RS12215	COG0426	domain, Protein
Thert_RS12220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Thert_RS12225	COG0163	prenyltransferase activity
Thert_RS12240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Thert_RS12250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Thert_RS12255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Thert_RS12265	COG1164	Oligoendopeptidase f
Thert_RS12275	COG1760	l-serine dehydratase
Thert_RS12280	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Thert_RS12285	COG0318	PFAM AMP-dependent synthetase and ligase
Thert_RS12290	COG0077	Prephenate dehydratase
Thert_RS12290	COG1605	Chorismate mutase
Thert_RS12295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Thert_RS12300	COG0287	Prephenate dehydrogenase
Thert_RS12310	COG0745	RESPONSE REGULATOR receiver
Thert_RS12315	COG5002	protein histidine kinase activity
Thert_RS12320	COG3773	Cell wall hydrolase
Thert_RS12320	COG3409	Peptidoglycan-binding domain 1 protein
Thert_RS12325	COG2119	membrane
Thert_RS12350	COG1940	carbohydrate kinase activity
Thert_RS12355	COG0363	glucosamine-6-phosphate deaminase activity
Thert_RS12360	COG0785	Cytochrome C biogenesis protein
Thert_RS12365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Thert_RS12375	COG0745	RESPONSE REGULATOR receiver
Thert_RS12380	COG2205	protein histidine kinase activity
Thert_RS12390	COG1982	Orn Lys Arg decarboxylase major
Thert_RS12395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Thert_RS12400	COG0477	Major facilitator Superfamily
Thert_RS12405	COG0789	Transcriptional regulator
Thert_RS12410	COG3885	ferrous iron binding
Thert_RS12410	COG2078	PFAM AMMECR1 domain protein
Thert_RS12435	COG1396	sequence-specific DNA binding
Thert_RS12450	COG4166	transmembrane transport
Thert_RS12455	COG0601	transmembrane transport
Thert_RS12465	COG0444	Belongs to the ABC transporter superfamily
Thert_RS12470	COG4172	Belongs to the ABC transporter superfamily
Thert_RS12475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Thert_RS12480	COG0181	hydroxymethylbilane synthase activity
Thert_RS12490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Thert_RS12495	COG1648	precorrin-2 dehydrogenase activity
Thert_RS12495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Thert_RS12500	COG0113	porphobilinogen synthase activity
Thert_RS12515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Thert_RS12530	COG2873	o-acetylhomoserine
Thert_RS12535	COG0175	sulfate reduction
Thert_RS12555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Thert_RS12560	COG0175	sulfate reduction
Thert_RS12595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Thert_RS12605	COG0494	nUDIX hydrolase
Thert_RS12610	COG1739	Uncharacterized protein family UPF0029
Thert_RS12630	COG0730	response to heat
Thert_RS12635	COG0217	transcriptional regulatory protein
Thert_RS12640	COG0835	chemotaxis
Thert_RS12650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Thert_RS12670	COG2385	sporulation resulting in formation of a cellular spore
Thert_RS12675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Thert_RS12680	COG0343	queuine tRNA-ribosyltransferase activity
Thert_RS12710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Thert_RS12715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Thert_RS12730	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Thert_RS12730	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Thert_RS12735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Thert_RS12740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Thert_RS12750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Thert_RS12770	COG0540	Belongs to the ATCase OTCase family
Thert_RS12785	COG0543	2 iron, 2 sulfur cluster binding
Thert_RS12790	COG0167	dihydroorotate dehydrogenase activity
Thert_RS12835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Thert_RS12840	COG1561	YicC-like family, N-terminal region
Thert_RS12850	COG0194	GDP metabolic process
Thert_RS12860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Thert_RS12865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Thert_RS12875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Thert_RS12885	COG2738	Putative neutral zinc metallopeptidase
Thert_RS12890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Thert_RS12890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Thert_RS12900	COG0631	protein serine/threonine phosphatase activity
Thert_RS12905	COG0515	serine threonine protein kinase
Thert_RS12905	COG2815	serine threonine protein kinase
Thert_RS12910	COG1162	GTPase activity
Thert_RS12915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Thert_RS12935	COG1302	Protein conserved in bacteria
Thert_RS12940	COG1461	Dihydroxyacetone kinase
Thert_RS12945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Thert_RS12950	COG1307	EDD domain protein, DegV family
Thert_RS12965	COG0742	ribosomal rna small subunit methyltransferase
Thert_RS12970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Thert_RS12980	COG3314	Sporulation integral membrane protein YlbJ
Thert_RS12990	COG0280	phosphate acetyltransferase
Thert_RS12995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Thert_RS13000	COG1399	metal-binding, possibly nucleic acid-binding protein
Thert_RS13005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Thert_RS13010	COG2030	dehydratase
Thert_RS13015	COG0416	fatty acid biosynthetic process
Thert_RS13020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Thert_RS13025	COG2070	2-Nitropropane dioxygenase
Thert_RS13030	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Thert_RS13045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Thert_RS13050	COG0571	ribonuclease III activity
Thert_RS13060	COG2359	stage V sporulation protein S
Thert_RS13065	COG1196	nuclear chromosome segregation
Thert_RS13070	COG0552	protein localization to endoplasmic reticulum
Thert_RS13100	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Thert_RS13105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Thert_RS13115	COG1837	Belongs to the UPF0109 family
Thert_RS13125	COG0336	Belongs to the RNA methyltransferase TrmD family
Thert_RS13140	COG0606	chelatase, subunit chli
Thert_RS13145	COG0180	Tryptophanyl-tRNA synthetase
Thert_RS13150	COG0792	nuclease activity
Thert_RS13155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Thert_RS13160	COG0758	DNA mediated transformation
Thert_RS13160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Thert_RS13165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Thert_RS13170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Thert_RS13175	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Thert_RS13185	COG1815	bacterial-type flagellum-dependent cell motility
Thert_RS13195	COG1677	Flagellar hook-basal body complex protein FliE
Thert_RS13200	COG1766	The M ring may be actively involved in energy transduction
Thert_RS13205	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Thert_RS13215	COG1157	protein secretion by the type III secretion system
Thert_RS13235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Thert_RS13245	COG1582	Flagellar protein (FlbD)
Thert_RS13250	COG1580	Controls the rotational direction of flagella during chemotaxis
Thert_RS13255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Thert_RS13260	COG1776	CheC inhibitor of MCP methylation
Thert_RS13260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Thert_RS13265	COG2201	protein-glutamate methylesterase activity
Thert_RS13275	COG1338	Plays a role in the flagellum-specific transport system
Thert_RS13280	COG1987	bacterial-type flagellum assembly
Thert_RS13285	COG1684	flagellar biosynthetic protein fliR
Thert_RS13290	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Thert_RS13295	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Thert_RS13305	COG0455	bacterial-type flagellum organization
Thert_RS13315	COG0643	Histidine kinase
Thert_RS13315	COG2198	Histidine kinase
Thert_RS13325	COG1776	CheC inhibitor of MCP methylation
Thert_RS13330	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Thert_RS13335	COG1191	sigma factor activity
Thert_RS13355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Thert_RS13360	COG0528	UMP kinase activity
Thert_RS13365	COG0233	cytoplasmic translational termination
Thert_RS13370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Thert_RS13380	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Thert_RS13385	COG0750	zinc metalloprotease
Thert_RS13390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Thert_RS13400	COG2176	DNA-directed DNA polymerase activity
Thert_RS13405	COG0779	Required for maturation of 30S ribosomal subunits
Thert_RS13410	COG0195	Participates in both transcription termination and antitermination
Thert_RS13415	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Thert_RS13430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Thert_RS13435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Thert_RS13440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Thert_RS13445	COG0196	riboflavin kinase activity
Thert_RS13450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Thert_RS13455	COG1185	polyribonucleotide nucleotidyltransferase activity
Thert_RS13460	COG0726	polysaccharide deacetylase
Thert_RS13465	COG0612	Peptidase, M16
Thert_RS13480	COG0527	aspartate kinase activity
Thert_RS13485	COG0740	serine-type endopeptidase activity
Thert_RS13495	COG1674	ftsk spoiiie
Thert_RS13500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Thert_RS13505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Thert_RS13510	COG1058	Belongs to the CinA family
Thert_RS13510	COG1546	Belongs to the CinA family
Thert_RS13515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Thert_RS13540	COG0420	3'-5' exonuclease activity
Thert_RS13545	COG0419	ATPase involved in DNA repair
Thert_RS13550	COG1418	mRNA catabolic process
Thert_RS13555	COG1692	metallophosphoesterase
Thert_RS13560	COG2359	stage V sporulation protein S
Thert_RS13565	COG0613	PHP domain protein
Thert_RS13575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Thert_RS13580	COG0017	Asparaginyl-tRNA synthetase
Thert_RS13585	COG0464	growth
Thert_RS13590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Thert_RS13595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Thert_RS13600	COG4974	Belongs to the 'phage' integrase family
Thert_RS13605	COG0328	RNA-DNA hybrid ribonuclease activity
Thert_RS13610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Thert_RS13625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Thert_RS13645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Thert_RS13660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Thert_RS13670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Thert_RS13680	COG2081	HI0933 family
Thert_RS13685	COG0406	alpha-ribazole phosphatase activity
Thert_RS13705	COG1388	LysM domain
Thert_RS13715	COG0010	Belongs to the arginase family
Thert_RS13720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Thert_RS13730	COG1187	pseudouridine synthase activity
Thert_RS13735	COG0445	tRNA wobble uridine modification
Thert_RS13745	COG1686	Belongs to the peptidase S11 family
Thert_RS13750	COG3874	Sporulation protein YtfJ
Thert_RS13760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Thert_RS13770	COG1994	Peptidase M50
Thert_RS13775	COG0617	tRNA 3'-terminal CCA addition
Thert_RS13775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Thert_RS13775	COG3620	sequence-specific DNA binding
Thert_RS13795	COG3360	Dodecin
Thert_RS13810	COG1366	Belongs to the anti-sigma-factor antagonist family
Thert_RS13815	COG1686	Belongs to the peptidase S11 family
Thert_RS13820	COG4974	Belongs to the 'phage' integrase family
Thert_RS13825	COG1300	Membrane
Thert_RS13830	COG1379	DNA repair
Thert_RS13835	COG0494	nUDIX hydrolase
Thert_RS13870	COG0750	zinc metalloprotease
Thert_RS13875	COG0497	DNA recombination
Thert_RS13880	COG1438	arginine binding
Thert_RS13890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Thert_RS13895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Thert_RS13905	COG0142	geranyltranstransferase activity
Thert_RS13915	COG1570	exodeoxyribonuclease VII activity
Thert_RS13920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Thert_RS13940	COG1302	Protein conserved in bacteria
Thert_RS13980	COG3854	ATPases associated with a variety of cellular activities
Thert_RS13995	COG0006	proline dipeptidase activity
Thert_RS14005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Thert_RS14060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Thert_RS14070	COG1459	type II secretion system
Thert_RS14080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Thert_RS14085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Thert_RS14090	COG0546	phosphoglycolate phosphatase activity
Thert_RS14095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Thert_RS14105	COG0768	penicillin binding
Thert_RS14110	COG0826	peptidase U32
Thert_RS14115	COG4122	O-methyltransferase activity
Thert_RS14120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Thert_RS14125	COG3679	Belongs to the UPF0342 family
Thert_RS14130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Thert_RS14135	COG0735	belongs to the Fur family
Thert_RS14140	COG3906	Belongs to the UPF0473 family
Thert_RS14150	COG4472	Bacterial protein of unknown function (DUF965)
Thert_RS14160	COG0628	permease
Thert_RS14205	COG1959	2 iron, 2 sulfur cluster binding
Thert_RS14210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Thert_RS14220	COG3118	belongs to the thioredoxin family
Thert_RS14225	COG1937	Protein conserved in bacteria
Thert_RS14230	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Thert_RS14250	COG0564	pseudouridine synthase activity
Thert_RS14255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Thert_RS14265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Thert_RS14285	COG3547	Transposase (IS116 IS110 IS902 family)
Thert_RS14300	COG0582	viral genome integration into host DNA
Thert_RS14335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Thert_RS14365	COG0512	Glutamine amidotransferase of anthranilate synthase
Thert_RS14365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)