locus-tag	class	description
NI17_RS00005	COG2329	Antibiotic biosynthesis monooxygenase
NI17_RS00010	COG5297	Belongs to the glycosyl hydrolase family 6
NI17_RS00015	COG0179	Fumarylacetoacetate (FAA) hydrolase
NI17_RS00020	COG2311	Membrane
NI17_RS00025	COG1725	Transcriptional regulator
NI17_RS00030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NI17_RS00050	COG2133	pyrroloquinoline quinone binding
NI17_RS00055	COG1414	Transcriptional regulator
NI17_RS00060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NI17_RS00065	COG0066	3-isopropylmalate dehydratase activity
NI17_RS00075	COG1920	GTP binding
NI17_RS00085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NI17_RS00095	COG1181	Belongs to the D-alanine--D-alanine ligase family
NI17_RS00110	COG4988	ABC transporter
NI17_RS00115	COG1294	oxidase, subunit
NI17_RS00120	COG1271	oxidase subunit
NI17_RS00155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NI17_RS00165	COG0742	ribosomal rna small subunit methyltransferase
NI17_RS00170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NI17_RS00180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NI17_RS00185	COG0571	ribonuclease III activity
NI17_RS00190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NI17_RS00195	COG1254	Belongs to the acylphosphatase family
NI17_RS00210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NI17_RS00215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS00220	COG0552	protein localization to endoplasmic reticulum
NI17_RS00240	COG1131	(ABC) transporter
NI17_RS00245	COG1510	regulation of RNA biosynthetic process
NI17_RS00265	COG0228	four-way junction DNA binding
NI17_RS00270	COG1837	Belongs to the UPF0109 family
NI17_RS00275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NI17_RS00280	COG0336	Belongs to the RNA methyltransferase TrmD family
NI17_RS00285	COG0335	large ribosomal subunit rRNA binding
NI17_RS00305	COG0792	nuclease activity
NI17_RS00325	COG4974	Belongs to the 'phage' integrase family
NI17_RS00335	COG0052	Belongs to the universal ribosomal protein uS2 family
NI17_RS00340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NI17_RS00345	COG0528	UMP kinase activity
NI17_RS00350	COG0233	cytoplasmic translational termination
NI17_RS00370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NI17_RS00380	COG1522	sequence-specific DNA binding
NI17_RS00390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NI17_RS00455	COG1105	Belongs to the carbohydrate kinase PfkB family
NI17_RS00465	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS00540	COG1201	RNA secondary structure unwinding
NI17_RS00610	COG1205	dead DEAH box helicase
NI17_RS00610	COG1111	helicase
NI17_RS00625	COG0210	DNA helicase
NI17_RS00680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS00695	COG1132	(ABC) transporter
NI17_RS00705	COG2226	methyltransferase
NI17_RS00710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NI17_RS00720	COG0583	DNA-binding transcription factor activity
NI17_RS00750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NI17_RS00770	COG2885	chlorophyll binding
NI17_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS00810	COG0750	zinc metalloprotease
NI17_RS00815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NI17_RS00820	COG0596	Alpha beta hydrolase
NI17_RS00870	COG0124	histidyl-tRNA synthetase
NI17_RS00890	COG0653	protein targeting
NI17_RS00920	COG1271	oxidase subunit
NI17_RS00925	COG2197	response regulator
NI17_RS00930	COG4585	Histidine kinase
NI17_RS00950	COG0442	prolyl-tRNA aminoacylation
NI17_RS00965	COG0779	Required for maturation of 30S ribosomal subunits
NI17_RS00980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NI17_RS00990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NI17_RS00995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NI17_RS01005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NI17_RS01010	COG1185	polyribonucleotide nucleotidyltransferase activity
NI17_RS01015	COG0612	Peptidase, M16
NI17_RS01020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NI17_RS01025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NI17_RS01040	COG1950	PFAM Membrane protein of
NI17_RS01045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NI17_RS01050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NI17_RS01055	COG1674	ftsk spoiiie
NI17_RS01065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NI17_RS01075	COG1058	Belongs to the CinA family
NI17_RS01075	COG1546	Belongs to the CinA family
NI17_RS01080	COG1396	sequence-specific DNA binding
NI17_RS01085	COG0783	Belongs to the Dps family
NI17_RS01105	COG1372	Participates in initiation and elongation during chromosome replication
NI17_RS01105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NI17_RS01105	COG1372	Participates in initiation and elongation during chromosome replication
NI17_RS01105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NI17_RS01110	COG2137	regulation of response to DNA damage stimulus
NI17_RS01115	COG1566	PFAM secretion protein HlyD family protein
NI17_RS01115	COG1418	mRNA catabolic process
NI17_RS01120	COG1505	serine-type exopeptidase activity
NI17_RS01125	COG0765	amino acid transport
NI17_RS01130	COG0765	amino acid transport
NI17_RS01135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NI17_RS01140	COG1126	abc transporter atp-binding protein
NI17_RS01145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NI17_RS01175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NI17_RS01180	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NI17_RS01200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NI17_RS01205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NI17_RS01210	COG1228	amidohydrolase
NI17_RS01240	COG0268	Binds directly to 16S ribosomal RNA
NI17_RS01250	COG0481	GTPase activity
NI17_RS01255	COG3833	ABC-type maltose transport systems, permease component
NI17_RS01260	COG1175	transmembrane transport
NI17_RS01270	COG0366	Alpha amylase catalytic
NI17_RS01280	COG2258	MOSC domain
NI17_RS01305	COG1420	regulation of RNA biosynthetic process
NI17_RS01310	COG0484	heat shock protein binding
NI17_RS01330	COG0537	adenosine 5'-monophosphoramidase activity
NI17_RS01340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NI17_RS01355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NI17_RS01360	COG1414	Transcriptional regulator
NI17_RS01380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NI17_RS01385	COG2340	Cysteine-rich secretory protein family
NI17_RS01390	COG1381	Involved in DNA repair and RecF pathway recombination
NI17_RS01395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NI17_RS01415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NI17_RS01420	COG1121	(ABC) transporter
NI17_RS01435	COG0423	glycine-tRNA ligase activity
NI17_RS01445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NI17_RS01445	COG0574	Belongs to the PEP-utilizing enzyme family
NI17_RS01455	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NI17_RS01465	COG0358	DNA primase activity
NI17_RS01470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NI17_RS01515	COG0659	secondary active sulfate transmembrane transporter activity
NI17_RS01530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NI17_RS01535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NI17_RS01540	COG3485	protocatechuate 3,4-dioxygenase
NI17_RS01545	COG3485	protocatechuate 3,4-dioxygenase
NI17_RS01550	COG0183	Belongs to the thiolase family
NI17_RS01555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NI17_RS01560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NI17_RS01565	COG1414	Transcriptional regulator
NI17_RS01570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NI17_RS01620	COG2814	Major facilitator Superfamily
NI17_RS01625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS01635	COG0702	epimerase
NI17_RS01645	COG1846	Transcriptional regulator
NI17_RS01650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NI17_RS01675	COG3546	catalase activity
NI17_RS01690	COG0300	oxidoreductase activity
NI17_RS01725	COG0859	PFAM glycosyl transferase family 9
NI17_RS01740	COG2192	nodulation
NI17_RS01760	COG0438	transferase activity, transferring glycosyl groups
NI17_RS01765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NI17_RS01770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NI17_RS01770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NI17_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS01780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NI17_RS01840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NI17_RS01865	COG1349	DNA-binding transcription factor activity
NI17_RS01875	COG1609	Transcriptional regulator
NI17_RS01885	COG0601	transmembrane transport
NI17_RS01890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NI17_RS01895	COG0444	Belongs to the ABC transporter superfamily
NI17_RS01925	COG4585	Histidine kinase
NI17_RS01965	COG1522	sequence-specific DNA binding
NI17_RS01970	COG3483	tryptophan 2,3-dioxygenase activity
NI17_RS02000	COG1476	TRANSCRIPTIONal
NI17_RS02030	COG0167	dihydroorotate dehydrogenase activity
NI17_RS02070	COG0395	ABC-type sugar transport system, permease component
NI17_RS02075	COG2723	6-phospho-beta-galactosidase activity
NI17_RS02090	COG4191	Histidine kinase
NI17_RS02095	COG2018	Roadblock/LC7 domain
NI17_RS02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NI17_RS02125	COG1960	acyl-CoA dehydrogenase activity
NI17_RS02135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NI17_RS02145	COG1252	NADH dehydrogenase
NI17_RS02160	COG1937	Protein conserved in bacteria
NI17_RS02215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NI17_RS02220	COG3336	cytochrome c oxidase
NI17_RS02285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS02290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NI17_RS02295	COG0174	glutamine synthetase
NI17_RS02300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NI17_RS02300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NI17_RS02315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NI17_RS02340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NI17_RS02345	COG0321	lipoyl(octanoyl) transferase activity
NI17_RS02350	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS02355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NI17_RS02360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NI17_RS02365	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NI17_RS02370	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
NI17_RS02380	COG4717	serine-type aminopeptidase activity
NI17_RS02385	COG0420	3'-5' exonuclease activity
NI17_RS02395	COG0667	Aldo Keto reductase
NI17_RS02415	COG0501	Belongs to the peptidase M48B family
NI17_RS02425	COG1929	Belongs to the glycerate kinase type-1 family
NI17_RS02435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NI17_RS02440	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NI17_RS02450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NI17_RS02455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NI17_RS02465	COG1376	ErfK ybiS ycfS ynhG family protein
NI17_RS02470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NI17_RS02475	COG0723	plastoquinol--plastocyanin reductase activity
NI17_RS02485	COG1845	cytochrome c oxidase, subunit III
NI17_RS02495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NI17_RS02530	COG1022	Amp-dependent synthetase and ligase
NI17_RS02540	COG1940	carbohydrate kinase activity
NI17_RS02570	COG0301	tRNA thio-modification
NI17_RS02575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NI17_RS02580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NI17_RS02585	COG0515	serine threonine protein kinase
NI17_RS02585	COG2815	serine threonine protein kinase
NI17_RS02590	COG2022	thiamine diphosphate biosynthetic process
NI17_RS02600	COG2022	thiamine diphosphate biosynthetic process
NI17_RS02600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS02610	COG0352	thiamine-phosphate diphosphorylase activity
NI17_RS02635	COG0142	geranyltranstransferase activity
NI17_RS02650	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NI17_RS02655	COG0540	Belongs to the ATCase OTCase family
NI17_RS02660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NI17_RS02665	COG0505	Belongs to the CarA family
NI17_RS02670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NI17_RS02675	COG0543	2 iron, 2 sulfur cluster binding
NI17_RS02680	COG0167	dihydroorotate dehydrogenase activity
NI17_RS02685	COG0284	orotidine-5'-phosphate decarboxylase activity
NI17_RS02695	COG0194	GDP metabolic process
NI17_RS02700	COG1758	RNA polymerase activity
NI17_RS02710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NI17_RS02715	COG2311	Membrane
NI17_RS02735	COG1960	acyl-CoA dehydrogenase activity
NI17_RS02760	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NI17_RS02775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NI17_RS02785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NI17_RS02795	COG3201	nicotinamide mononucleotide transporter
NI17_RS02800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NI17_RS02800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NI17_RS02805	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NI17_RS02815	COG2017	converts alpha-aldose to the beta-anomer
NI17_RS02820	COG0515	serine threonine protein kinase
NI17_RS02820	COG2815	serine threonine protein kinase
NI17_RS02850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NI17_RS02855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NI17_RS02860	COG0419	ATPase involved in DNA repair
NI17_RS02870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NI17_RS02875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NI17_RS02880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NI17_RS02890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NI17_RS02910	COG0714	Associated with various cellular activities
NI17_RS02915	COG2001	Belongs to the MraZ family
NI17_RS02920	COG0275	rRNA processing
NI17_RS02930	COG0768	penicillin binding
NI17_RS02935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NI17_RS02945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NI17_RS02950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NI17_RS02960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NI17_RS02965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NI17_RS02970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NI17_RS02975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NI17_RS02980	COG1496	oxidoreductase activity
NI17_RS02985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NI17_RS02990	COG1799	cell septum assembly
NI17_RS03000	COG3599	regulation of cell shape
NI17_RS03010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NI17_RS03020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NI17_RS03030	COG1309	transcriptional regulator
NI17_RS03090	COG2318	DinB family
NI17_RS03135	COG2153	protein acetylation
NI17_RS03145	COG0477	Major facilitator Superfamily
NI17_RS03160	COG1132	(ABC) transporter
NI17_RS03190	COG1695	Transcriptional regulator
NI17_RS03200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NI17_RS03210	COG1528	Iron-storage protein
NI17_RS03215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NI17_RS03220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NI17_RS03225	COG0131	Imidazoleglycerol-phosphate dehydratase
NI17_RS03235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NI17_RS03240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NI17_RS03245	COG0107	imidazoleglycerol-phosphate synthase activity
NI17_RS03255	COG1132	(ABC) transporter
NI17_RS03265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NI17_RS03290	COG0134	indole-3-glycerol-phosphate synthase activity
NI17_RS03295	COG0133	tryptophan synthase activity
NI17_RS03300	COG0159	tryptophan synthase activity
NI17_RS03315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NI17_RS03335	COG0070	glutamate synthase
NI17_RS03335	COG0069	glutamate synthase activity
NI17_RS03335	COG0067	glutamate synthase
NI17_RS03360	COG0693	protein deglycase activity
NI17_RS03420	COG2050	protein possibly involved in aromatic compounds catabolism
NI17_RS03430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NI17_RS03435	COG0539	negative regulation of cytoplasmic translation
NI17_RS03440	COG0237	dephospho-CoA kinase activity
NI17_RS03445	COG0556	nucleotide-excision repair
NI17_RS03460	COG0504	CTP synthase activity
NI17_RS03485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NI17_RS03490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NI17_RS03510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NI17_RS03515	COG1160	GTP binding
NI17_RS03535	COG1733	regulation of RNA biosynthetic process
NI17_RS03540	COG1683	Conserved Protein
NI17_RS03560	COG0395	ABC-type sugar transport system, permease component
NI17_RS03575	COG1609	Transcriptional regulator
NI17_RS03580	COG2233	PERMEase
NI17_RS03585	COG0483	inositol monophosphate 1-phosphatase activity
NI17_RS03610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS03620	COG2814	Major facilitator Superfamily
NI17_RS03640	COG0463	Glycosyl transferase, family 2
NI17_RS03650	COG0463	Glycosyl transferase, family 2
NI17_RS03655	COG2814	Major facilitator Superfamily
NI17_RS03660	COG0561	phosphatase activity
NI17_RS03665	COG0242	peptide deformylase activity
NI17_RS03685	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NI17_RS03720	COG0673	inositol 2-dehydrogenase activity
NI17_RS03735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NI17_RS03740	COG4948	Mandelate Racemase Muconate Lactonizing
NI17_RS03745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS03745	COG0723	plastoquinol--plastocyanin reductase activity
NI17_RS03750	COG1609	Transcriptional regulator
NI17_RS03770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS03790	COG0747	negative chemotaxis
NI17_RS03795	COG0601	transmembrane transport
NI17_RS03800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NI17_RS03810	COG4608	Belongs to the ABC transporter superfamily
NI17_RS03830	COG1609	Transcriptional regulator
NI17_RS03855	COG0673	inositol 2-dehydrogenase activity
NI17_RS03860	COG1175	transmembrane transport
NI17_RS03865	COG0395	ABC-type sugar transport system, permease component
NI17_RS03870	COG1653	transport
NI17_RS03875	COG2755	lipolytic protein G-D-S-L family
NI17_RS03875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NI17_RS03880	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS03885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NI17_RS03890	COG2072	flavoprotein involved in K transport
NI17_RS03900	COG1132	(ABC) transporter
NI17_RS03915	COG2226	methyltransferase
NI17_RS03945	COG0243	molybdopterin cofactor binding
NI17_RS03955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NI17_RS03955	COG2111	Na H antiporter
NI17_RS03960	COG2111	Na H antiporter
NI17_RS03965	COG1006	Multisubunit Na H antiporter MnhC subunit
NI17_RS03970	COG0651	ATP synthesis coupled electron transport
NI17_RS03980	COG2212	antiporter activity
NI17_RS03985	COG1320	monovalent cation:proton antiporter activity
NI17_RS03990	COG0028	Belongs to the TPP enzyme family
NI17_RS03995	COG0277	FAD linked oxidase domain protein
NI17_RS03995	COG0247	lactate metabolic process
NI17_RS04005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NI17_RS04025	COG0110	maltose O-acetyltransferase activity
NI17_RS04090	COG1253	flavin adenine dinucleotide binding
NI17_RS04095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NI17_RS04100	COG2813	Specifically methylates the guanine in position
NI17_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS04125	COG2304	oxidoreductase activity
NI17_RS04135	COG0714	Associated with various cellular activities
NI17_RS04145	COG0667	Aldo Keto reductase
NI17_RS04150	COG3540	Alkaline phosphatase
NI17_RS04165	COG3842	ATPase activity
NI17_RS04175	COG2239	Acts as a magnesium transporter
NI17_RS04200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NI17_RS04230	COG1162	GTPase activity
NI17_RS04240	COG2885	chlorophyll binding
NI17_RS04250	COG2205	protein histidine kinase activity
NI17_RS04275	COG2267	carboxylic ester hydrolase activity
NI17_RS04295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NI17_RS04315	COG1357	PFAM Pentapeptide repeats (8 copies)
NI17_RS04320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NI17_RS04325	COG0515	serine threonine protein kinase
NI17_RS04325	COG2815	serine threonine protein kinase
NI17_RS04340	COG1285	pathogenesis
NI17_RS04345	COG3387	PFAM Glycoside hydrolase 15-related
NI17_RS04350	COG2364	Membrane
NI17_RS04355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NI17_RS04360	COG2267	carboxylic ester hydrolase activity
NI17_RS04365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NI17_RS04375	COG2815	serine threonine protein kinase
NI17_RS04375	COG0515	serine threonine protein kinase
NI17_RS04385	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NI17_RS04480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS04495	COG1690	Belongs to the RtcB family
NI17_RS04520	COG0746	molybdenum cofactor guanylyltransferase activity
NI17_RS04545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NI17_RS04550	COG1316	TRANSCRIPTIONal
NI17_RS04560	COG1131	(ABC) transporter
NI17_RS04575	COG2186	Transcriptional regulator
NI17_RS04580	COG2807	transmembrane transport
NI17_RS04600	COG1960	acyl-CoA dehydrogenase activity
NI17_RS04625	COG0789	Transcriptional regulator
NI17_RS04665	COG1966	Carbon starvation protein
NI17_RS04675	COG0003	Pfam Anion-transporting ATPase
NI17_RS04690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NI17_RS04710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NI17_RS04710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NI17_RS04735	COG1476	TRANSCRIPTIONal
NI17_RS04740	COG1515	deoxyribonuclease V activity
NI17_RS04750	COG4585	Histidine kinase
NI17_RS04755	COG2197	response regulator
NI17_RS04780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NI17_RS04790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NI17_RS04795	COG4948	Mandelate Racemase Muconate Lactonizing
NI17_RS04800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NI17_RS04815	COG1649	PFAM Uncharacterised BCR, COG1649
NI17_RS04845	COG1289	transmembrane transporter activity
NI17_RS04885	COG0789	Transcriptional regulator
NI17_RS04890	COG5006	permease, DMT superfamily
NI17_RS04910	COG0598	Magnesium transport protein CorA
NI17_RS04915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NI17_RS04920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NI17_RS04925	COG0318	PFAM AMP-dependent synthetase and ligase
NI17_RS05010	COG0028	Belongs to the TPP enzyme family
NI17_RS05030	COG1176	ABC-type spermidine putrescine transport system, permease component I
NI17_RS05040	COG3842	ATPase activity
NI17_RS05075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS05100	COG0515	serine threonine protein kinase
NI17_RS05150	COG3903	Transcriptional regulator
NI17_RS05150	COG3629	intracellular signal transduction
NI17_RS05165	COG1403	HNH endonuclease
NI17_RS05175	COG0210	DNA helicase
NI17_RS05205	COG2318	DinB family
NI17_RS05215	COG1309	transcriptional regulator
NI17_RS05230	COG0517	IMP dehydrogenase activity
NI17_RS05230	COG1994	Peptidase M50
NI17_RS05280	COG1131	(ABC) transporter
NI17_RS05290	COG1309	transcriptional regulator
NI17_RS05310	COG0596	Alpha beta hydrolase
NI17_RS05320	COG2365	Tyrosine phosphatase family
NI17_RS05325	COG2271	Major facilitator Superfamily
NI17_RS05355	COG1902	pentaerythritol trinitrate reductase activity
NI17_RS05375	COG0714	Associated with various cellular activities
NI17_RS05385	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NI17_RS05395	COG2208	phosphoserine phosphatase activity
NI17_RS05400	COG0596	Alpha beta hydrolase
NI17_RS05420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS05425	COG0492	ferredoxin-NADP+ reductase activity
NI17_RS05430	COG1169	isochorismate synthase
NI17_RS05435	COG3433	isochorismatase activity
NI17_RS05435	COG1535	isochorismatase
NI17_RS05445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS05445	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NI17_RS05470	COG2375	cellular response to nickel ion
NI17_RS05470	COG1132	(ABC) transporter
NI17_RS05490	COG4166	transmembrane transport
NI17_RS05495	COG0601	transmembrane transport
NI17_RS05500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NI17_RS05515	COG3458	cephalosporin-C deacetylase activity
NI17_RS05545	COG0582	viral genome integration into host DNA
NI17_RS05620	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS05645	COG1960	acyl-CoA dehydrogenase activity
NI17_RS05650	COG2070	2-Nitropropane dioxygenase
NI17_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS05675	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS05690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NI17_RS05710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NI17_RS05740	COG0657	acetylesterase activity
NI17_RS05745	COG0446	pyridine nucleotide-disulphide oxidoreductase
NI17_RS05745	COG1902	pentaerythritol trinitrate reductase activity
NI17_RS05750	COG2072	flavoprotein involved in K transport
NI17_RS05785	COG1302	Protein conserved in bacteria
NI17_RS05795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS05800	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS05805	COG1120	ATPase activity
NI17_RS05825	COG1404	Belongs to the peptidase S8 family
NI17_RS05840	COG1309	transcriptional regulator
NI17_RS05880	COG2267	carboxylic ester hydrolase activity
NI17_RS05890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NI17_RS05905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NI17_RS05945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NI17_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS05965	COG2814	Major facilitator Superfamily
NI17_RS06010	COG0671	phosphoesterase, PA-phosphatase related
NI17_RS06015	COG2267	carboxylic ester hydrolase activity
NI17_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS06055	COG4948	Mandelate Racemase Muconate Lactonizing
NI17_RS06075	COG3118	belongs to the thioredoxin family
NI17_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS06090	COG1132	(ABC) transporter
NI17_RS06105	COG1120	ATPase activity
NI17_RS06110	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS06115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS06195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NI17_RS06230	COG0789	Transcriptional regulator
NI17_RS06240	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS06250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NI17_RS06280	COG0601	transmembrane transport
NI17_RS06300	COG2723	6-phospho-beta-galactosidase activity
NI17_RS06310	COG1802	Transcriptional regulator
NI17_RS06315	COG5006	permease, DMT superfamily
NI17_RS06345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NI17_RS06360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NI17_RS06365	COG0726	polysaccharide deacetylase
NI17_RS06370	COG0740	serine-type endopeptidase activity
NI17_RS06375	COG1396	sequence-specific DNA binding
NI17_RS06380	COG1609	Transcriptional regulator
NI17_RS06385	COG1653	transport
NI17_RS06390	COG1175	transmembrane transport
NI17_RS06420	COG1501	Belongs to the glycosyl hydrolase 31 family
NI17_RS06435	COG3842	ATPase activity
NI17_RS06440	COG0488	(ABC) transporter
NI17_RS06450	COG0395	ABC-type sugar transport system, permease component
NI17_RS06455	COG4209	transmembrane transport
NI17_RS06465	COG1940	carbohydrate kinase activity
NI17_RS06470	COG1472	Belongs to the glycosyl hydrolase 3 family
NI17_RS06530	COG1518	maintenance of DNA repeat elements
NI17_RS06535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NI17_RS06575	COG0110	maltose O-acetyltransferase activity
NI17_RS06615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NI17_RS06645	COG2084	Dehydrogenase
NI17_RS06685	COG3708	Transcriptional regulator
NI17_RS06685	COG2207	Transcriptional regulator
NI17_RS06690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NI17_RS06695	COG4335	DNA alkylation repair
NI17_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS06780	COG2124	cytochrome p450
NI17_RS06790	COG0604	alcohol dehydrogenase
NI17_RS06800	COG0183	Belongs to the thiolase family
NI17_RS06810	COG1024	Enoyl-CoA hydratase
NI17_RS06815	COG1960	acyl-CoA dehydrogenase activity
NI17_RS06820	COG1960	acyl-CoA dehydrogenase activity
NI17_RS06840	COG2030	dehydratase
NI17_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS06850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NI17_RS06885	COG0477	Major facilitator Superfamily
NI17_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS06930	COG4106	trans-aconitate 2-methyltransferase activity
NI17_RS06940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS06965	COG1595	DNA-templated transcription, initiation
NI17_RS06970	COG1252	NADH dehydrogenase
NI17_RS06975	COG0477	Major facilitator Superfamily
NI17_RS06980	COG0659	secondary active sulfate transmembrane transporter activity
NI17_RS06995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NI17_RS07000	COG0789	Transcriptional regulator
NI17_RS07010	COG3973	AAA domain
NI17_RS07015	COG1007	ATP synthesis coupled electron transport
NI17_RS07020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NI17_RS07025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NI17_RS07030	COG0713	ATP synthesis coupled electron transport
NI17_RS07040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NI17_RS07050	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NI17_RS07060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NI17_RS07060	COG0512	Glutamine amidotransferase of anthranilate synthase
NI17_RS07080	COG1121	(ABC) transporter
NI17_RS07085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NI17_RS07095	COG1280	lysine exporter protein (LysE YggA)
NI17_RS07110	COG0583	DNA-binding transcription factor activity
NI17_RS07125	COG0179	Fumarylacetoacetate (FAA) hydrolase
NI17_RS07135	COG2267	carboxylic ester hydrolase activity
NI17_RS07155	COG4608	Belongs to the ABC transporter superfamily
NI17_RS07180	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS07185	COG0579	oxidoreductase
NI17_RS07195	COG0028	Belongs to the TPP enzyme family
NI17_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS07240	COG0243	molybdopterin cofactor binding
NI17_RS07245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NI17_RS07250	COG2890	protein-(glutamine-N5) methyltransferase activity
NI17_RS07260	COG2815	serine threonine protein kinase
NI17_RS07260	COG0515	serine threonine protein kinase
NI17_RS07265	COG3321	synthase
NI17_RS07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS07290	COG2267	carboxylic ester hydrolase activity
NI17_RS07305	COG1309	transcriptional regulator
NI17_RS07310	COG1132	(ABC) transporter
NI17_RS07365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NI17_RS07380	COG0673	inositol 2-dehydrogenase activity
NI17_RS07390	COG1505	serine-type exopeptidase activity
NI17_RS07400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NI17_RS07400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NI17_RS07405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NI17_RS07420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NI17_RS07420	COG2146	nitrite reductase [NAD(P)H] activity
NI17_RS07425	COG2146	nitrite reductase [NAD(P)H] activity
NI17_RS07425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NI17_RS07440	COG4585	Histidine kinase
NI17_RS07445	COG2197	response regulator
NI17_RS07460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS07480	COG1234	tRNA 3'-trailer cleavage
NI17_RS07485	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NI17_RS07515	COG0439	Biotin carboxylase
NI17_RS07585	COG2226	methyltransferase
NI17_RS07590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS07590	COG3321	synthase
NI17_RS07595	COG1309	transcriptional regulator
NI17_RS07620	COG4974	Belongs to the 'phage' integrase family
NI17_RS07690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NI17_RS07695	COG2154	pterin-4-alpha-carbinolamine dehydratase
NI17_RS07715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS07790	COG3189	MarR family transcriptional regulator
NI17_RS07840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NI17_RS07840	COG2885	chlorophyll binding
NI17_RS07850	COG2072	flavoprotein involved in K transport
NI17_RS07865	COG3973	AAA domain
NI17_RS07880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS07935	COG1070	Carbohydrate kinase
NI17_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS07940	COG3347	Dehydrogenase
NI17_RS07945	COG4952	isomerase
NI17_RS07955	COG1879	ABC-type sugar transport system periplasmic component
NI17_RS07960	COG1172	Belongs to the binding-protein-dependent transport system permease family
NI17_RS07970	COG1129	ABC transporter
NI17_RS07975	COG1609	Transcriptional regulator
NI17_RS07985	COG1070	Carbohydrate kinase
NI17_RS08025	COG0640	Transcriptional regulator
NI17_RS08030	COG2217	Heavy metal translocating P-type atpase
NI17_RS08040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NI17_RS08045	COG0514	ATP-dependent DNA helicase (RecQ)
NI17_RS08100	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NI17_RS08105	COG0602	queuosine metabolic process
NI17_RS08110	COG0720	synthase
NI17_RS08120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS08135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NI17_RS08160	COG0583	DNA-binding transcription factor activity
NI17_RS08175	COG0254	rRNA binding
NI17_RS08195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NI17_RS08220	COG0596	Alpha beta hydrolase
NI17_RS08250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NI17_RS08265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS08270	COG3251	PFAM MbtH domain protein
NI17_RS08290	COG0134	indole-3-glycerol-phosphate synthase activity
NI17_RS08310	COG0159	tryptophan synthase activity
NI17_RS08320	COG0134	indole-3-glycerol-phosphate synthase activity
NI17_RS08355	COG3795	YCII-related domain
NI17_RS08360	COG4941	Belongs to the sigma-70 factor family
NI17_RS08365	COG0477	Major facilitator Superfamily
NI17_RS08410	COG1917	Cupin 2, conserved barrel domain protein
NI17_RS08410	COG4977	sequence-specific DNA binding
NI17_RS08420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NI17_RS08465	COG2124	cytochrome p450
NI17_RS08495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NI17_RS08515	COG1063	alcohol dehydrogenase
NI17_RS08525	COG1902	pentaerythritol trinitrate reductase activity
NI17_RS08540	COG3250	beta-galactosidase activity
NI17_RS08545	COG1175	transmembrane transport
NI17_RS08575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS08610	COG2249	NAD(P)H dehydrogenase (quinone) activity
NI17_RS08620	COG1278	Cold shock
NI17_RS08630	COG2323	membrane
NI17_RS08640	COG2124	cytochrome p450
NI17_RS08645	COG4221	oxidoreductase activity
NI17_RS08670	COG2192	nodulation
NI17_RS08715	COG0679	Auxin Efflux Carrier
NI17_RS08725	COG0179	Fumarylacetoacetate (FAA) hydrolase
NI17_RS08735	COG0667	Aldo Keto reductase
NI17_RS08750	COG0477	Major facilitator Superfamily
NI17_RS08755	COG0583	DNA-binding transcription factor activity
NI17_RS08780	COG1304	FMN binding
NI17_RS08785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NI17_RS08810	COG1024	Enoyl-CoA hydratase
NI17_RS08815	COG0183	Belongs to the thiolase family
NI17_RS08850	COG1024	Enoyl-CoA hydratase
NI17_RS08855	COG0318	PFAM AMP-dependent synthetase and ligase
NI17_RS08865	COG1960	acyl-CoA dehydrogenase activity
NI17_RS08880	COG1569	PIN domain
NI17_RS08885	COG3311	Transcriptional regulator
NI17_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS08900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NI17_RS08900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NI17_RS08905	COG1703	isobutyryl-CoA mutase activity
NI17_RS08910	COG1024	Enoyl-CoA hydratase
NI17_RS08915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NI17_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS08935	COG1250	3-hydroxyacyl-CoA dehydrogenase
NI17_RS08940	COG1024	Enoyl-CoA hydratase
NI17_RS08995	COG1053	succinate dehydrogenase
NI17_RS09010	COG1053	succinate dehydrogenase
NI17_RS09015	COG1902	pentaerythritol trinitrate reductase activity
NI17_RS09015	COG0446	pyridine nucleotide-disulphide oxidoreductase
NI17_RS09025	COG2030	dehydratase
NI17_RS09030	COG0789	Transcriptional regulator
NI17_RS09040	COG0789	Transcriptional regulator
NI17_RS09055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NI17_RS09065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS09070	COG0655	NAD(P)H dehydrogenase (quinone) activity
NI17_RS09075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NI17_RS09115	COG1960	acyl-CoA dehydrogenase activity
NI17_RS09120	COG0300	oxidoreductase activity
NI17_RS09135	COG0346	lactoylglutathione lyase activity
NI17_RS09145	COG0583	DNA-binding transcription factor activity
NI17_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS09190	COG0583	DNA-binding transcription factor activity
NI17_RS09195	COG3795	YCII-related domain
NI17_RS09200	COG4941	Belongs to the sigma-70 factor family
NI17_RS09220	COG0535	radical SAM domain protein
NI17_RS09235	COG2192	nodulation
NI17_RS09240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NI17_RS09245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NI17_RS09260	COG0252	asparaginase activity
NI17_RS09305	COG1309	transcriptional regulator
NI17_RS09365	COG1132	(ABC) transporter
NI17_RS09370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NI17_RS09515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NI17_RS09560	COG0124	histidyl-tRNA synthetase
NI17_RS09570	COG1131	(ABC) transporter
NI17_RS09590	COG0019	diaminopimelate decarboxylase activity
NI17_RS09630	COG2801	Transposase and inactivated derivatives
NI17_RS09640	COG2963	transposase activity
NI17_RS09860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS09865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS09885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NI17_RS09890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NI17_RS09930	COG0494	nUDIX hydrolase
NI17_RS09935	COG1388	LysM domain
NI17_RS09935	COG3103	Sh3 type 3 domain protein
NI17_RS09935	COG0791	NLP P60 protein
NI17_RS09970	COG3321	synthase
NI17_RS09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS10085	COG0640	Transcriptional regulator
NI17_RS10160	COG3103	Sh3 type 3 domain protein
NI17_RS10160	COG1388	LysM domain
NI17_RS10160	COG0791	NLP P60 protein
NI17_RS10270	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NI17_RS10275	COG1518	maintenance of DNA repeat elements
NI17_RS10285	COG1203	CRISPR-associated helicase, Cas3
NI17_RS10315	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NI17_RS10325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NI17_RS10390	COG0667	Aldo Keto reductase
NI17_RS10410	COG3103	Sh3 type 3 domain protein
NI17_RS10410	COG0791	NLP P60 protein
NI17_RS10410	COG1388	LysM domain
NI17_RS10420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS10580	COG1203	CRISPR-associated helicase, Cas3
NI17_RS10595	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NI17_RS10605	COG4974	Belongs to the 'phage' integrase family
NI17_RS10635	COG3103	Sh3 type 3 domain protein
NI17_RS10635	COG0791	NLP P60 protein
NI17_RS10635	COG1388	LysM domain
NI17_RS10710	COG1510	regulation of RNA biosynthetic process
NI17_RS10715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NI17_RS10720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NI17_RS10735	COG1278	Cold shock
NI17_RS10755	COG0583	DNA-binding transcription factor activity
NI17_RS10760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NI17_RS10765	COG1216	Glycosyl transferase, family 2
NI17_RS10775	COG0006	proline dipeptidase activity
NI17_RS10835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NI17_RS10845	COG1120	ATPase activity
NI17_RS10850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS10860	COG1742	UPF0060 membrane protein
NI17_RS10865	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
NI17_RS10870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NI17_RS10880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NI17_RS10900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NI17_RS10905	COG2378	regulation of single-species biofilm formation
NI17_RS10910	COG3739	integral membrane protein
NI17_RS10960	COG3842	ATPase activity
NI17_RS10965	COG0438	transferase activity, transferring glycosyl groups
NI17_RS10970	COG0366	Alpha amylase catalytic
NI17_RS10975	COG4581	dead DEAH box helicase
NI17_RS10990	COG0805	protein transport
NI17_RS11035	COG1960	acyl-CoA dehydrogenase activity
NI17_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS11075	COG2186	Transcriptional regulator
NI17_RS11080	COG4948	Mandelate Racemase Muconate Lactonizing
NI17_RS11090	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NI17_RS11095	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NI17_RS11100	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NI17_RS11115	COG4122	O-methyltransferase activity
NI17_RS11125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NI17_RS11135	COG1222	aaa ATPase
NI17_RS11170	COG1994	Peptidase M50
NI17_RS11170	COG0517	IMP dehydrogenase activity
NI17_RS11180	COG2197	response regulator
NI17_RS11220	COG0646	methionine synthase
NI17_RS11220	COG1410	methionine synthase
NI17_RS11245	COG0215	cysteine-tRNA ligase activity
NI17_RS11280	COG1968	undecaprenyl-diphosphatase activity
NI17_RS11285	COG0667	Aldo Keto reductase
NI17_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS11320	COG2197	response regulator
NI17_RS11325	COG4585	Histidine kinase
NI17_RS11330	COG0577	efflux transmembrane transporter activity
NI17_RS11330	COG1136	(ABC) transporter
NI17_RS11335	COG0577	efflux transmembrane transporter activity
NI17_RS11335	COG1136	(ABC) transporter
NI17_RS11380	COG2091	lysine biosynthetic process via aminoadipic acid
NI17_RS11385	COG1505	serine-type exopeptidase activity
NI17_RS11475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NI17_RS11485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NI17_RS11490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NI17_RS11510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NI17_RS11520	COG1021	2,3-dihydroxybenzoate-AMP ligase
NI17_RS11525	COG1169	isochorismate synthase
NI17_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS11540	COG0701	Predicted permease
NI17_RS11545	COG2130	NADP-dependent
NI17_RS11555	COG0513	Belongs to the DEAD box helicase family
NI17_RS11570	COG0488	(ABC) transporter
NI17_RS11625	COG0175	sulfate reduction
NI17_RS11635	COG1960	acyl-CoA dehydrogenase activity
NI17_RS11650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NI17_RS11655	COG0688	phosphatidylethanolamine metabolic process
NI17_RS11690	COG3253	May function as heme-dependent peroxidase
NI17_RS11695	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NI17_RS11705	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NI17_RS11725	COG0183	Belongs to the thiolase family
NI17_RS11760	COG4941	Belongs to the sigma-70 factor family
NI17_RS11765	COG3795	YCII-related domain
NI17_RS11770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NI17_RS11775	COG2409	Drug exporters of the RND superfamily
NI17_RS11795	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NI17_RS11800	COG0493	'glutamate synthase
NI17_RS11810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NI17_RS11815	COG3663	DNA glycosylase
NI17_RS11825	COG4214	carbohydrate transport
NI17_RS11835	COG4213	ABC transporter substrate-binding protein
NI17_RS11840	COG1940	carbohydrate kinase activity
NI17_RS11850	COG1595	DNA-templated transcription, initiation
NI17_RS11865	COG4607	ABC-type enterochelin transport system periplasmic component
NI17_RS11870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS11875	COG4605	iron ion homeostasis
NI17_RS11880	COG4604	ABC transporter, ATP-binding protein
NI17_RS11895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NI17_RS11905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NI17_RS11910	COG0569	domain protein
NI17_RS11920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NI17_RS11945	COG0756	dUTP diphosphatase activity
NI17_RS11950	COG0525	valine-tRNA ligase activity
NI17_RS11970	COG2205	protein histidine kinase activity
NI17_RS11975	COG0745	RESPONSE REGULATOR receiver
NI17_RS11995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NI17_RS12030	COG0288	reversible hydration of carbon dioxide
NI17_RS12055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NI17_RS12070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NI17_RS12080	COG4733	cellulase activity
NI17_RS12080	COG5297	Belongs to the glycosyl hydrolase family 6
NI17_RS12090	COG0009	L-threonylcarbamoyladenylate synthase
NI17_RS12100	COG2318	DinB family
NI17_RS12105	COG2813	Specifically methylates the guanine in position
NI17_RS12110	COG1396	sequence-specific DNA binding
NI17_RS12160	COG0432	Pfam Uncharacterised protein family UPF0047
NI17_RS12170	COG1984	allophanate hydrolase subunit 2
NI17_RS12175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NI17_RS12180	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NI17_RS12200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NI17_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NI17_RS12210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NI17_RS12240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NI17_RS12250	COG2151	metal-sulfur cluster biosynthetic enzyme
NI17_RS12255	COG0822	iron-sulfur transferase activity
NI17_RS12265	COG0396	ATPase activity
NI17_RS12290	COG1131	(ABC) transporter
NI17_RS12305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NI17_RS12310	COG2235	arginine
NI17_RS12315	COG5006	permease, DMT superfamily
NI17_RS12345	COG0318	PFAM AMP-dependent synthetase and ligase
NI17_RS12350	COG1960	acyl-CoA dehydrogenase activity
NI17_RS12360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NI17_RS12370	COG0109	protoheme IX farnesyltransferase activity
NI17_RS12380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NI17_RS12400	COG0363	glucosamine-6-phosphate deaminase activity
NI17_RS12435	COG3401	FG-GAP repeat protein
NI17_RS12455	COG0531	amino acid
NI17_RS12470	COG0400	carboxylic ester hydrolase activity
NI17_RS12475	COG0346	lactoylglutathione lyase activity
NI17_RS12485	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NI17_RS12490	COG0149	triose-phosphate isomerase activity
NI17_RS12495	COG0126	phosphoglycerate kinase activity
NI17_RS12500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NI17_RS12505	COG1481	regulation of sporulation
NI17_RS12515	COG1660	Displays ATPase and GTPase activities
NI17_RS12520	COG0322	excinuclease ABC activity
NI17_RS12540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NI17_RS12575	COG0497	DNA recombination
NI17_RS12580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NI17_RS12610	COG0647	UMP catabolic process
NI17_RS12625	COG0456	acetyltransferase
NI17_RS12655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NI17_RS12680	COG5002	protein histidine kinase activity
NI17_RS12700	COG2018	Roadblock/LC7 domain
NI17_RS12710	COG0165	Argininosuccinate lyase
NI17_RS12715	COG0137	argininosuccinate synthase activity
NI17_RS12720	COG1438	arginine binding
NI17_RS12725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NI17_RS12730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NI17_RS12735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NI17_RS12740	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NI17_RS12745	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NI17_RS12750	COG1846	Transcriptional regulator
NI17_RS12760	COG0745	RESPONSE REGULATOR receiver
NI17_RS12765	COG2205	protein histidine kinase activity
NI17_RS12775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NI17_RS12775	COG0072	phenylalanine-tRNA ligase activity
NI17_RS12780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NI17_RS12785	COG5002	protein histidine kinase activity
NI17_RS12790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NI17_RS12795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NI17_RS12800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NI17_RS12805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NI17_RS12810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NI17_RS12820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NI17_RS12825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NI17_RS12830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NI17_RS12840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS12915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NI17_RS12925	COG1196	nuclear chromosome segregation
NI17_RS12935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NI17_RS12940	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NI17_RS12945	COG1862	Preprotein translocase
NI17_RS12950	COG2255	four-way junction helicase activity
NI17_RS12955	COG0632	four-way junction helicase activity
NI17_RS12960	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NI17_RS12965	COG0217	transcriptional regulatory protein
NI17_RS12970	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NI17_RS12975	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NI17_RS12985	COG0438	transferase activity, transferring glycosyl groups
NI17_RS12990	COG1560	Kdo2-lipid A biosynthetic process
NI17_RS12995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NI17_RS13010	COG1253	flavin adenine dinucleotide binding
NI17_RS13025	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NI17_RS13085	COG3265	gluconokinase activity
NI17_RS13135	COG1733	regulation of RNA biosynthetic process
NI17_RS13145	COG1011	Hydrolase
NI17_RS13200	COG0045	succinate-CoA ligase (ADP-forming) activity
NI17_RS13210	COG0514	ATP-dependent DNA helicase (RecQ)
NI17_RS13210	COG0514	ATP-dependent DNA helicase (RecQ)
NI17_RS13220	COG1320	monovalent cation:proton antiporter activity
NI17_RS13225	COG2212	antiporter activity
NI17_RS13230	COG1863	multisubunit Na H antiporter MnhE subunit
NI17_RS13235	COG0651	ATP synthesis coupled electron transport
NI17_RS13240	COG1006	Multisubunit Na H antiporter MnhC subunit
NI17_RS13245	COG2111	Na H antiporter
NI17_RS13250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NI17_RS13250	COG2111	Na H antiporter
NI17_RS13255	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NI17_RS13275	COG0187	DNA topoisomerase II activity
NI17_RS13290	COG3022	response to hydroperoxide
NI17_RS13305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NI17_RS13325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NI17_RS13335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NI17_RS13360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NI17_RS13365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NI17_RS13370	COG1388	LysM domain
NI17_RS13375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NI17_RS13395	COG0495	leucyl-tRNA aminoacylation
NI17_RS13405	COG0318	PFAM AMP-dependent synthetase and ligase
NI17_RS13410	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NI17_RS13425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NI17_RS13435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NI17_RS13475	COG0395	ABC-type sugar transport system, permease component
NI17_RS13480	COG1175	transmembrane transport
NI17_RS13490	COG1609	Transcriptional regulator
NI17_RS13560	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NI17_RS13565	COG0501	Belongs to the peptidase M48B family
NI17_RS13585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NI17_RS13605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NI17_RS13610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NI17_RS13615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NI17_RS13620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NI17_RS13625	COG1530	ribonuclease E activity
NI17_RS13650	COG0772	Belongs to the SEDS family
NI17_RS13665	COG0105	UTP biosynthetic process
NI17_RS13675	COG0285	dihydrofolate synthase activity
NI17_RS13700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NI17_RS13705	COG0740	serine-type endopeptidase activity
NI17_RS13710	COG0740	serine-type endopeptidase activity
NI17_RS13715	COG0544	peptidyl-prolyl cis-trans isomerase activity
NI17_RS13730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NI17_RS13730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NI17_RS13735	COG1132	(ABC) transporter
NI17_RS13750	COG2239	Acts as a magnesium transporter
NI17_RS13760	COG4552	Acetyltransferase involved in intracellular survival and related
NI17_RS13780	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NI17_RS13810	COG0129	dihydroxy-acid dehydratase activity
NI17_RS13825	COG1505	serine-type exopeptidase activity
NI17_RS13835	COG2271	Major facilitator Superfamily
NI17_RS13870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NI17_RS13870	COG1648	precorrin-2 dehydrogenase activity
NI17_RS13875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NI17_RS13920	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NI17_RS13935	COG0431	NADPH-dependent FMN reductase
NI17_RS13955	COG1176	ABC-type spermidine putrescine transport system, permease component I
NI17_RS13965	COG3842	ATPase activity
NI17_RS13985	COG0235	Class ii aldolase
NI17_RS13995	COG4585	Histidine kinase
NI17_RS14000	COG2197	response regulator
NI17_RS14005	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NI17_RS14010	COG3766	membrane
NI17_RS14035	COG1522	sequence-specific DNA binding
NI17_RS14060	COG0477	Major facilitator Superfamily
NI17_RS14070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NI17_RS14075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NI17_RS14090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NI17_RS14115	COG1115	amino acid carrier protein
NI17_RS14135	COG0583	DNA-binding transcription factor activity
NI17_RS14150	COG0438	transferase activity, transferring glycosyl groups
NI17_RS14185	COG1597	lipid kinase activity
NI17_RS14215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NI17_RS14235	COG2894	cell division
NI17_RS14260	COG4585	Histidine kinase
NI17_RS14320	COG0667	Aldo Keto reductase
NI17_RS14340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NI17_RS14360	COG1230	cation diffusion facilitator family transporter
NI17_RS14365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NI17_RS14370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NI17_RS14375	COG0569	domain protein
NI17_RS14405	COG1960	acyl-CoA dehydrogenase activity
NI17_RS14410	COG1960	acyl-CoA dehydrogenase activity
NI17_RS14420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NI17_RS14425	COG1122	ATPase activity
NI17_RS14430	COG1268	BioY protein
NI17_RS14435	COG2706	6-phosphogluconolactonase activity
NI17_RS14455	COG2018	Roadblock/LC7 domain
NI17_RS14465	COG1643	Atp-dependent helicase
NI17_RS14520	COG1737	Transcriptional regulator
NI17_RS14525	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NI17_RS14530	COG2949	membrane
NI17_RS14560	COG1595	DNA-templated transcription, initiation
NI17_RS14575	COG0753	catalase activity
NI17_RS14585	COG0210	DNA helicase
NI17_RS14630	COG3395	kinase activity
NI17_RS14635	COG0673	inositol 2-dehydrogenase activity
NI17_RS14640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NI17_RS14645	COG1653	transport
NI17_RS14650	COG1175	transmembrane transport
NI17_RS14655	COG0395	ABC-type sugar transport system, permease component
NI17_RS14665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NI17_RS14670	COG0784	Response regulator, receiver
NI17_RS14675	COG4251	negative regulation of phosphorylation
NI17_RS14685	COG5398	heme oxygenase
NI17_RS14715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NI17_RS14720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NI17_RS14725	COG0509	glycine decarboxylation via glycine cleavage system
NI17_RS14730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NI17_RS14780	COG0515	serine threonine protein kinase
NI17_RS14780	COG2815	serine threonine protein kinase
NI17_RS14790	COG1025	Belongs to the peptidase M16 family
NI17_RS14810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NI17_RS14815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NI17_RS14820	COG1234	tRNA 3'-trailer cleavage
NI17_RS14850	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NI17_RS14860	COG1335	isochorismatase
NI17_RS14895	COG1678	Uncharacterized ACR, COG1678
NI17_RS14915	COG0183	Belongs to the thiolase family
NI17_RS14940	COG1250	3-hydroxyacyl-CoA dehydrogenase
NI17_RS14950	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NI17_RS14990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NI17_RS14995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NI17_RS15000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NI17_RS15005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NI17_RS15010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NI17_RS15015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NI17_RS15020	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NI17_RS15040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NI17_RS15050	COG2890	protein-(glutamine-N5) methyltransferase activity
NI17_RS15055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NI17_RS15060	COG0254	rRNA binding
NI17_RS15070	COG0083	homoserine kinase activity
NI17_RS15075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NI17_RS15080	COG0460	homoserine dehydrogenase
NI17_RS15085	COG0019	diaminopimelate decarboxylase activity
NI17_RS15095	COG0745	RESPONSE REGULATOR receiver
NI17_RS15105	COG2272	Belongs to the type-B carboxylesterase lipase family
NI17_RS15135	COG0242	peptide deformylase activity
NI17_RS15205	COG1061	Type III restriction enzyme res subunit
NI17_RS15210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NI17_RS15215	COG1053	succinate dehydrogenase
NI17_RS15225	COG0583	DNA-binding transcription factor activity
NI17_RS15230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS15235	COG1217	gtp-binding protein TYPA
NI17_RS15240	COG0494	nUDIX hydrolase
NI17_RS15280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NI17_RS15285	COG2177	Part of the ABC transporter FtsEX involved in
NI17_RS15290	COG2884	Cell division ATP-binding protein ftsE
NI17_RS15295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NI17_RS15305	COG2902	Dehydrogenase
NI17_RS15320	COG1011	Hydrolase
NI17_RS15330	COG1472	Belongs to the glycosyl hydrolase 3 family
NI17_RS15355	COG0653	protein targeting
NI17_RS15365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NI17_RS15375	COG5401	PFAM Sporulation and spore germination
NI17_RS15380	COG5000	phosphorelay sensor kinase activity
NI17_RS15380	COG5002	protein histidine kinase activity
NI17_RS15385	COG0745	RESPONSE REGULATOR receiver
NI17_RS15405	COG0714	Associated with various cellular activities
NI17_RS15425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NI17_RS15445	COG2835	tetraacyldisaccharide 4'-kinase activity
NI17_RS15485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NI17_RS15490	COG0778	Nitroreductase
NI17_RS15490	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
NI17_RS15495	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NI17_RS15500	COG2226	methyltransferase
NI17_RS15510	COG2188	Transcriptional regulator
NI17_RS15585	COG1316	TRANSCRIPTIONal
NI17_RS15675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NI17_RS15690	COG1316	TRANSCRIPTIONal
NI17_RS15700	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NI17_RS15705	COG1832	CoA-binding protein
NI17_RS15725	COG0745	RESPONSE REGULATOR receiver
NI17_RS15730	COG5002	protein histidine kinase activity
NI17_RS15740	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NI17_RS15750	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NI17_RS15755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NI17_RS15765	COG4770	biotin carboxylase activity
NI17_RS15825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NI17_RS15830	COG1473	amidohydrolase
NI17_RS15830	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NI17_RS15835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NI17_RS15840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NI17_RS15845	COG1316	TRANSCRIPTIONal
NI17_RS15865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NI17_RS15870	COG0138	bifunctional purine biosynthesis protein purh
NI17_RS15895	COG0045	succinate-CoA ligase (ADP-forming) activity
NI17_RS15930	COG1957	nucleoside hydrolase
NI17_RS15935	COG2197	response regulator
NI17_RS15940	COG4585	Histidine kinase
NI17_RS15955	COG2080	2 iron, 2 sulfur cluster binding
NI17_RS15975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NI17_RS15975	COG0519	Catalyzes the synthesis of GMP from XMP
NI17_RS15990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NI17_RS16005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NI17_RS16015	COG0516	GMP reductase activity
NI17_RS16025	COG1595	DNA-templated transcription, initiation
NI17_RS16030	COG0459	protein refolding
NI17_RS16035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NI17_RS16060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NI17_RS16075	COG0802	atpase or kinase
NI17_RS16080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NI17_RS16110	COG1072	(Pantothenic acid kinase))
NI17_RS16120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NI17_RS16125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NI17_RS16130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NI17_RS16135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NI17_RS16145	COG0101	tRNA pseudouridine synthase activity
NI17_RS16150	COG0203	ribosomal protein L17
NI17_RS16155	COG0202	RNA polymerase activity
NI17_RS16160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NI17_RS16165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NI17_RS16170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NI17_RS16175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NI17_RS16190	COG0563	adenylate kinase activity
NI17_RS16200	COG0200	Binds to the 23S rRNA
NI17_RS16205	COG1841	ribosomal large subunit assembly
NI17_RS16210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NI17_RS16215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NI17_RS16220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NI17_RS16225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NI17_RS16230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NI17_RS16235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NI17_RS16240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NI17_RS16245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NI17_RS16250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NI17_RS16255	COG0255	Belongs to the universal ribosomal protein uL29 family
NI17_RS16260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NI17_RS16265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NI17_RS16270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NI17_RS16275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NI17_RS16280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NI17_RS16285	COG0089	rRNA binding
NI17_RS16290	COG0088	Forms part of the polypeptide exit tunnel
NI17_RS16295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NI17_RS16300	COG0051	transcription antitermination factor activity, RNA binding
NI17_RS16305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NI17_RS16310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NI17_RS16315	COG0049	tRNA binding
NI17_RS16320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NI17_RS16330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NI17_RS16335	COG0085	RNA polymerase activity
NI17_RS16345	COG0222	ribosome binding
NI17_RS16350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NI17_RS16360	COG0081	regulation of translation
NI17_RS16365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NI17_RS16375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NI17_RS16385	COG0436	Aminotransferase
NI17_RS16390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NI17_RS16395	COG2119	membrane
NI17_RS16400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NI17_RS16410	COG2030	dehydratase
NI17_RS16415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NI17_RS16430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NI17_RS16455	COG1309	transcriptional regulator
NI17_RS16470	COG1666	GTP binding
NI17_RS16475	COG0501	Belongs to the peptidase M48B family
NI17_RS16480	COG0674	pyruvate-flavodoxin oxidoreductase activity
NI17_RS16480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NI17_RS16485	COG1013	pyruvate-flavodoxin oxidoreductase activity
NI17_RS16490	COG0671	phosphoesterase, PA-phosphatase related
NI17_RS16495	COG0702	epimerase
NI17_RS16515	COG1595	DNA-templated transcription, initiation
NI17_RS16525	COG2161	toxin-antitoxin pair type II binding
NI17_RS16535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NI17_RS16550	COG0142	geranyltranstransferase activity
NI17_RS16555	COG1007	ATP synthesis coupled electron transport
NI17_RS16570	COG0713	ATP synthesis coupled electron transport
NI17_RS16580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NI17_RS16585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NI17_RS16590	COG1034	ATP synthesis coupled electron transport
NI17_RS16605	COG0649	NAD binding
NI17_RS16610	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NI17_RS16615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NI17_RS16630	COG2226	methyltransferase
NI17_RS16650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NI17_RS16655	COG1333	cytochrome c biogenesis protein
NI17_RS16660	COG0785	Cytochrome C biogenesis protein
NI17_RS16665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NI17_RS16680	COG0123	including yeast histone deacetylase and acetoin utilization protein
NI17_RS16685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NI17_RS16695	COG1082	Xylose isomerase domain protein TIM barrel
NI17_RS16705	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NI17_RS16745	COG2897	thiosulfate sulfurtransferase activity
NI17_RS16775	COG0406	alpha-ribazole phosphatase activity
NI17_RS16785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NI17_RS16790	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NI17_RS16805	COG0113	porphobilinogen synthase activity
NI17_RS16815	COG0181	hydroxymethylbilane synthase activity
NI17_RS16820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NI17_RS16825	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NI17_RS16840	COG0745	RESPONSE REGULATOR receiver
NI17_RS16850	COG0456	acetyltransferase
NI17_RS16865	COG0581	inorganic phosphate transmembrane transporter activity
NI17_RS16870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NI17_RS16875	COG0306	phosphate transporter
NI17_RS16895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NI17_RS16940	COG1739	Uncharacterized protein family UPF0029
NI17_RS16950	COG0386	Belongs to the glutathione peroxidase family
NI17_RS16980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NI17_RS17005	COG1486	melibiose metabolic process
NI17_RS17015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NI17_RS17065	COG2188	Transcriptional regulator
NI17_RS17095	COG0582	viral genome integration into host DNA
NI17_RS17115	COG1774	PSP1 C-terminal conserved region
NI17_RS17120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NI17_RS17135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NI17_RS17140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NI17_RS17140	COG1754	DNA topoisomerase type I activity
NI17_RS17160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NI17_RS17185	COG1609	Transcriptional regulator
NI17_RS17190	COG2382	esterase
NI17_RS17190	COG3507	Belongs to the glycosyl hydrolase 43 family
NI17_RS17190	COG3693	PFAM glycoside hydrolase, family 10
NI17_RS17210	COG0714	Associated with various cellular activities
NI17_RS17225	COG0438	transferase activity, transferring glycosyl groups
NI17_RS17340	COG1140	nitrate reductase beta subunit
NI17_RS17395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS17425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NI17_RS17460	COG1201	RNA secondary structure unwinding
NI17_RS17520	COG0789	Transcriptional regulator
NI17_RS17565	COG3903	Transcriptional regulator
NI17_RS17565	COG3629	intracellular signal transduction
NI17_RS17620	COG2813	Specifically methylates the guanine in position
NI17_RS17625	COG0515	serine threonine protein kinase
NI17_RS17625	COG2815	serine threonine protein kinase
NI17_RS17630	COG0210	DNA helicase
NI17_RS17650	COG2124	cytochrome p450
NI17_RS17675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NI17_RS17680	COG2197	response regulator
NI17_RS17690	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NI17_RS17690	COG1703	isobutyryl-CoA mutase activity
NI17_RS17690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NI17_RS17700	COG1063	alcohol dehydrogenase
NI17_RS17715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NI17_RS17730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NI17_RS17735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NI17_RS17745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NI17_RS17765	COG0247	lactate metabolic process
NI17_RS17770	COG1139	Iron-sulfur cluster binding protein
NI17_RS17775	COG1556	Lactate utilization protein
NI17_RS17780	COG1309	transcriptional regulator
NI17_RS17785	COG2814	Major facilitator Superfamily
NI17_RS17805	COG0277	FAD linked oxidase domain protein
NI17_RS17805	COG0247	lactate metabolic process
NI17_RS17810	COG0515	serine threonine protein kinase
NI17_RS17900	COG1115	amino acid carrier protein
NI17_RS17910	COG2186	Transcriptional regulator
NI17_RS17915	COG3629	intracellular signal transduction
NI17_RS17915	COG3903	Transcriptional regulator
NI17_RS17920	COG2814	Major facilitator Superfamily
NI17_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS17945	COG2814	Major facilitator Superfamily
NI17_RS17950	COG0604	alcohol dehydrogenase
NI17_RS17950	COG3321	synthase
NI17_RS17955	COG3903	Transcriptional regulator
NI17_RS17955	COG3629	intracellular signal transduction
NI17_RS17960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NI17_RS17965	COG3275	phosphorelay sensor kinase activity
NI17_RS17970	COG3279	Response regulator of the LytR AlgR family
NI17_RS17980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NI17_RS17990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NI17_RS17995	COG0640	Transcriptional regulator
NI17_RS18000	COG0492	ferredoxin-NADP+ reductase activity
NI17_RS18020	COG0640	Transcriptional regulator
NI17_RS18025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NI17_RS18030	COG0798	PFAM Bile acid sodium symporter
NI17_RS18035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NI17_RS18045	COG2072	flavoprotein involved in K transport
NI17_RS18155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NI17_RS18160	COG2144	transferase activity, transferring acyl groups
NI17_RS18205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NI17_RS18280	COG3485	protocatechuate 3,4-dioxygenase
NI17_RS18325	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NI17_RS18335	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NI17_RS18345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NI17_RS18350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NI17_RS18355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NI17_RS18370	COG3655	Transcriptional regulator
NI17_RS18410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NI17_RS18420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NI17_RS18425	COG0302	gtp cyclohydrolase
NI17_RS18435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NI17_RS18440	COG0037	tRNA processing
NI17_RS18470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NI17_RS18475	COG2027	D-alanyl-D-alanine carboxypeptidase
NI17_RS18485	COG2814	Major facilitator Superfamily
NI17_RS18490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NI17_RS18495	COG1329	Transcriptional regulator
NI17_RS18505	COG5002	protein histidine kinase activity
NI17_RS18515	COG0588	phosphoglycerate mutase activity
NI17_RS18525	COG0438	transferase activity, transferring glycosyl groups
NI17_RS18550	COG0501	Belongs to the peptidase M48B family
NI17_RS18575	COG1490	D-aminoacyl-tRNA deacylase activity
NI17_RS18610	COG2113	Glycine betaine
NI17_RS18620	COG4175	Glycine betaine
NI17_RS18620	COG3448	diguanylate cyclase activity
NI17_RS18625	COG0705	Rhomboid family
NI17_RS18630	COG0717	Belongs to the dCTP deaminase family
NI17_RS18665	COG0596	Alpha beta hydrolase
NI17_RS18670	COG1316	TRANSCRIPTIONal
NI17_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS18695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NI17_RS18725	COG0435	Glutathione S-transferase
NI17_RS18735	COG0702	epimerase
NI17_RS18760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NI17_RS18770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NI17_RS18775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NI17_RS18775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NI17_RS18800	COG2311	Membrane
NI17_RS18825	COG1324	tolerance protein
NI17_RS18830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NI17_RS18850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NI17_RS18855	COG0151	Belongs to the GarS family
NI17_RS18870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NI17_RS18875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NI17_RS18880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NI17_RS18890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NI17_RS18910	COG1595	DNA-templated transcription, initiation
NI17_RS18955	COG0179	Fumarylacetoacetate (FAA) hydrolase
NI17_RS18970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS19030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NI17_RS19035	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NI17_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS19100	COG2205	protein histidine kinase activity
NI17_RS19105	COG2197	response regulator
NI17_RS19125	COG1316	TRANSCRIPTIONal
NI17_RS19205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NI17_RS19230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NI17_RS19250	COG4941	Belongs to the sigma-70 factor family
NI17_RS19265	COG1051	belongs to the nudix hydrolase family
NI17_RS19290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS19305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NI17_RS19305	COG0512	Glutamine amidotransferase of anthranilate synthase
NI17_RS19310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NI17_RS19325	COG0277	FAD linked oxidase domain protein
NI17_RS19330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NI17_RS19335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NI17_RS19400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NI17_RS19405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NI17_RS19450	COG0589	response to stress
NI17_RS19455	COG0617	tRNA 3'-terminal CCA addition
NI17_RS19455	COG0517	IMP dehydrogenase activity
NI17_RS19455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NI17_RS19460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NI17_RS19485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NI17_RS19490	COG0443	Heat shock 70 kDa protein
NI17_RS19495	COG0484	heat shock protein binding
NI17_RS19510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NI17_RS19515	COG0022	dehydrogenase e1 component
NI17_RS19515	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS19520	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS19535	COG0586	Pfam SNARE associated Golgi protein
NI17_RS19545	COG1215	transferase activity, transferring glycosyl groups
NI17_RS19550	COG1366	Belongs to the anti-sigma-factor antagonist family
NI17_RS19560	COG5002	protein histidine kinase activity
NI17_RS19565	COG0425	Belongs to the sulfur carrier protein TusA family
NI17_RS19565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NI17_RS19585	COG1716	ATPase activity
NI17_RS19600	COG0768	penicillin binding
NI17_RS19605	COG0515	serine threonine protein kinase
NI17_RS19610	COG0515	serine threonine protein kinase
NI17_RS19620	COG0705	Rhomboid family
NI17_RS19680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NI17_RS19700	COG2837	iron assimilation
NI17_RS19740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NI17_RS19745	COG4977	sequence-specific DNA binding
NI17_RS19805	COG0359	binds to the 23S rRNA
NI17_RS19810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NI17_RS19815	COG0629	single-stranded DNA binding
NI17_RS19820	COG0360	Binds together with S18 to 16S ribosomal RNA
NI17_RS19830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NI17_RS19885	COG2018	Roadblock/LC7 domain
NI17_RS19915	COG0515	serine threonine protein kinase
NI17_RS19915	COG2815	serine threonine protein kinase
NI17_RS19920	COG1595	DNA-templated transcription, initiation
NI17_RS19930	COG0492	ferredoxin-NADP+ reductase activity
NI17_RS19935	COG3118	belongs to the thioredoxin family
NI17_RS19945	COG1192	Involved in chromosome partitioning
NI17_RS19950	COG0357	Ribosomal RNA small subunit methyltransferase G
NI17_RS19960	COG0706	membrane insertase activity
NI17_RS19965	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NI17_RS19970	COG0594	ribonuclease P activity
NI17_RS19975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NI17_RS19985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NI17_RS19990	COG0592	DNA-directed DNA polymerase activity
NI17_RS19995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NI17_RS20000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NI17_RS20005	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
NI17_RS20010	COG0187	DNA topoisomerase II activity
NI17_RS20015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NI17_RS20060	COG1518	maintenance of DNA repeat elements
NI17_RS20085	COG2208	phosphoserine phosphatase activity
NI17_RS20085	COG2770	Histidine kinase
NI17_RS20130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NI17_RS20170	COG2089	acid synthase
NI17_RS20175	COG1216	Glycosyl transferase, family 2
NI17_RS20185	COG2755	lipolytic protein G-D-S-L family
NI17_RS20185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NI17_RS20205	COG1482	cell wall glycoprotein biosynthetic process
NI17_RS20245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NI17_RS20280	COG1674	ftsk spoiiie
NI17_RS20370	COG1366	Belongs to the anti-sigma-factor antagonist family
NI17_RS20375	COG1366	Belongs to the anti-sigma-factor antagonist family
NI17_RS20380	COG2172	sigma factor antagonist activity
NI17_RS20395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NI17_RS20450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NI17_RS20455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NI17_RS20460	COG3387	PFAM Glycoside hydrolase 15-related
NI17_RS20465	COG0587	DNA-directed DNA polymerase activity
NI17_RS20690	COG1674	ftsk spoiiie
NI17_RS20730	COG2183	response to ionizing radiation
NI17_RS20760	COG0039	L-malate dehydrogenase activity
NI17_RS20780	COG0592	DNA-directed DNA polymerase activity
NI17_RS20805	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NI17_RS20815	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS20870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NI17_RS20890	COG1960	acyl-CoA dehydrogenase activity
NI17_RS20905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NI17_RS20915	COG0745	RESPONSE REGULATOR receiver
NI17_RS20935	COG2315	Protein conserved in bacteria
NI17_RS20975	COG2208	phosphoserine phosphatase activity
NI17_RS20980	COG2208	phosphoserine phosphatase activity
NI17_RS20985	COG2208	phosphoserine phosphatase activity
NI17_RS20990	COG1408	metallophosphoesterase
NI17_RS21000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NI17_RS21035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NI17_RS21065	COG1366	Belongs to the anti-sigma-factor antagonist family
NI17_RS21070	COG1111	helicase
NI17_RS21070	COG1205	dead DEAH box helicase
NI17_RS21120	COG0596	Alpha beta hydrolase
NI17_RS21130	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NI17_RS21140	COG0560	Phosphoserine phosphatase
NI17_RS21140	COG3830	Belongs to the UPF0237 family
NI17_RS21160	COG1119	ATPase activity
NI17_RS21175	COG0446	pyridine nucleotide-disulphide oxidoreductase
NI17_RS21185	COG1309	transcriptional regulator
NI17_RS21190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NI17_RS21195	COG2843	Capsule synthesis protein
NI17_RS21205	COG0753	catalase activity
NI17_RS21225	COG2226	methyltransferase
NI17_RS21240	COG3866	Pectate lyase
NI17_RS21250	COG0657	acetylesterase activity
NI17_RS21255	COG0047	phosphoribosylformylglycinamidine synthase activity
NI17_RS21265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NI17_RS21285	COG1476	TRANSCRIPTIONal
NI17_RS21295	COG1131	(ABC) transporter
NI17_RS21305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NI17_RS21340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NI17_RS21355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NI17_RS21365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NI17_RS21370	COG0140	phosphoribosyl-ATP diphosphatase activity
NI17_RS21375	COG0300	oxidoreductase activity
NI17_RS21385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NI17_RS21390	COG1595	DNA-templated transcription, initiation
NI17_RS21400	COG0022	dehydrogenase e1 component
NI17_RS21405	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS21420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NI17_RS21440	COG0706	membrane insertase activity
NI17_RS21450	COG0181	hydroxymethylbilane synthase activity
NI17_RS21460	COG0800	Aldolase
NI17_RS21515	COG0247	lactate metabolic process
NI17_RS21515	COG2181	nitrate reductase activity
NI17_RS21520	COG0443	Heat shock 70 kDa protein
NI17_RS21525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NI17_RS21530	COG0484	heat shock protein binding
NI17_RS21535	COG0789	Transcriptional regulator
NI17_RS21540	COG0542	response to heat
NI17_RS21565	COG1960	acyl-CoA dehydrogenase activity
NI17_RS21575	COG0215	cysteine-tRNA ligase activity
NI17_RS21580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NI17_RS21600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NI17_RS21635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NI17_RS21640	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NI17_RS21645	COG0459	protein refolding
NI17_RS21685	COG1278	Cold shock
NI17_RS21720	COG2252	PERMEase
NI17_RS21730	COG2814	Major facilitator Superfamily
NI17_RS21735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NI17_RS21745	COG0584	glycerophosphoryl diester phosphodiesterase
NI17_RS21765	COG0259	pyridoxamine-phosphate oxidase activity
NI17_RS21775	COG1366	Belongs to the anti-sigma-factor antagonist family
NI17_RS21775	COG2172	sigma factor antagonist activity
NI17_RS21775	COG2208	phosphoserine phosphatase activity
NI17_RS21785	COG1295	ribonuclease BN
NI17_RS21795	COG0183	Belongs to the thiolase family
NI17_RS21810	COG2205	protein histidine kinase activity
NI17_RS21815	COG0745	RESPONSE REGULATOR receiver
NI17_RS21825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NI17_RS21840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NI17_RS21840	COG0116	Belongs to the methyltransferase superfamily
NI17_RS21845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NI17_RS21940	COG0416	fatty acid biosynthetic process
NI17_RS21950	COG1940	carbohydrate kinase activity
NI17_RS21965	COG1024	Enoyl-CoA hydratase
NI17_RS21975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NI17_RS21980	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS21985	COG3842	ATPase activity
NI17_RS21995	COG1176	ABC-type spermidine putrescine transport system, permease component I
NI17_RS22000	COG1177	transmembrane transport
NI17_RS22005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NI17_RS22015	COG3850	Histidine kinase
NI17_RS22015	COG3437	response regulator, receiver
NI17_RS22015	COG2205	protein histidine kinase activity
NI17_RS22015	COG4999	Histidine kinase
NI17_RS22030	COG2212	antiporter activity
NI17_RS22035	COG1863	multisubunit Na H antiporter MnhE subunit
NI17_RS22040	COG0651	ATP synthesis coupled electron transport
NI17_RS22045	COG1006	Multisubunit Na H antiporter MnhC subunit
NI17_RS22050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NI17_RS22050	COG2111	Na H antiporter
NI17_RS22055	COG2197	response regulator
NI17_RS22060	COG4585	Histidine kinase
NI17_RS22095	COG0438	transferase activity, transferring glycosyl groups
NI17_RS22105	COG0631	protein serine/threonine phosphatase activity
NI17_RS22110	COG1276	copper resistance
NI17_RS22110	COG2372	response to copper ion
NI17_RS22120	COG0456	acetyltransferase
NI17_RS22130	COG1917	Cupin 2, conserved barrel domain protein
NI17_RS22135	COG5285	phytanoyl-CoA dioxygenase
NI17_RS22145	COG0765	amino acid transport
NI17_RS22150	COG0765	amino acid transport
NI17_RS22155	COG1126	abc transporter atp-binding protein
NI17_RS22160	COG1492	cobalamin metabolic process
NI17_RS22170	COG1797	cobyrinic acid a,c-diamide synthase activity
NI17_RS22255	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS22255	COG0596	Alpha beta hydrolase
NI17_RS22280	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NI17_RS22285	COG0494	nUDIX hydrolase
NI17_RS22285	COG0406	alpha-ribazole phosphatase activity
NI17_RS22320	COG0725	ABC transporter, periplasmic molybdate-binding protein
NI17_RS22325	COG4585	Histidine kinase
NI17_RS22360	COG1120	ATPase activity
NI17_RS22365	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS22370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NI17_RS22395	COG0745	RESPONSE REGULATOR receiver
NI17_RS22405	COG1320	monovalent cation:proton antiporter activity
NI17_RS22410	COG2212	antiporter activity
NI17_RS22420	COG0651	ATP synthesis coupled electron transport
NI17_RS22425	COG1006	Multisubunit Na H antiporter MnhC subunit
NI17_RS22430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NI17_RS22430	COG2111	Na H antiporter
NI17_RS22435	COG1846	Transcriptional regulator
NI17_RS22445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NI17_RS22470	COG0589	response to stress
NI17_RS22475	COG3973	AAA domain
NI17_RS22480	COG3384	dioxygenase
NI17_RS22485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NI17_RS22530	COG1802	Transcriptional regulator
NI17_RS22615	COG1674	ftsk spoiiie
NI17_RS22620	COG1404	Belongs to the peptidase S8 family
NI17_RS22655	COG1876	peptidase activity
NI17_RS22660	COG1970	mechanosensitive ion channel activity
NI17_RS22685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NI17_RS22695	COG0315	cyclic pyranopterin monophosphate synthase activity
NI17_RS22700	COG0521	Mo-molybdopterin cofactor biosynthetic process
NI17_RS22705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NI17_RS22730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NI17_RS22760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NI17_RS22770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NI17_RS22795	COG0084	hydrolase, TatD family'
NI17_RS22800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NI17_RS22835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NI17_RS22845	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NI17_RS22850	COG0789	Transcriptional regulator
NI17_RS22855	COG0488	(ABC) transporter
NI17_RS22865	COG1846	Transcriptional regulator
NI17_RS22890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NI17_RS22895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NI17_RS22900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NI17_RS22905	COG0193	aminoacyl-tRNA hydrolase activity
NI17_RS22910	COG1218	3'(2'),5'-bisphosphate nucleotidase
NI17_RS22925	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NI17_RS22930	COG1959	2 iron, 2 sulfur cluster binding
NI17_RS22950	COG0529	Catalyzes the synthesis of activated sulfate
NI17_RS22965	COG0730	response to heat
NI17_RS22970	COG0148	phosphopyruvate hydratase activity
NI17_RS22990	COG1252	NADH dehydrogenase
NI17_RS23000	COG1012	belongs to the aldehyde dehydrogenase family
NI17_RS23005	COG0506	proline dehydrogenase activity
NI17_RS23020	COG0183	Belongs to the thiolase family
NI17_RS23025	COG2755	lipolytic protein G-D-S-L family
NI17_RS23035	COG0110	maltose O-acetyltransferase activity
NI17_RS23065	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
NI17_RS23080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NI17_RS23090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NI17_RS23100	COG1331	Highly conserved protein containing a thioredoxin domain
NI17_RS23110	COG0515	serine threonine protein kinase
NI17_RS23110	COG2815	serine threonine protein kinase
NI17_RS23120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NI17_RS23125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NI17_RS23135	COG0114	fumarate hydratase activity
NI17_RS23150	COG0842	Transport permease protein
NI17_RS23180	COG1722	exodeoxyribonuclease VII activity
NI17_RS23185	COG1570	exodeoxyribonuclease VII activity
NI17_RS23200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NI17_RS23210	COG1322	Protein conserved in bacteria
NI17_RS23215	COG0012	GTP binding
NI17_RS23295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NI17_RS23305	COG1994	Peptidase M50
NI17_RS23335	COG2171	N-acyltransferase activity
NI17_RS23340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NI17_RS23345	COG1611	Belongs to the LOG family
NI17_RS23355	COG0519	Catalyzes the synthesis of GMP from XMP
NI17_RS23370	COG1024	Enoyl-CoA hydratase
NI17_RS23380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NI17_RS23385	COG4122	O-methyltransferase activity
NI17_RS23390	COG1595	DNA-templated transcription, initiation
NI17_RS23405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NI17_RS23425	COG0613	PHP domain protein
NI17_RS23440	COG0513	Belongs to the DEAD box helicase family
NI17_RS23460	COG0668	transmembrane transport
NI17_RS23495	COG0210	DNA helicase
NI17_RS23530	COG1946	Acyl-CoA thioesterase
NI17_RS23550	COG0415	Belongs to the DNA photolyase family
NI17_RS23570	COG0314	molybdopterin synthase activity
NI17_RS23575	COG3480	Lon protease (S16) C-terminal proteolytic domain
NI17_RS23585	COG1615	UPF0182 protein
NI17_RS23620	COG0577	efflux transmembrane transporter activity
NI17_RS23620	COG1136	(ABC) transporter
NI17_RS23625	COG0483	inositol monophosphate 1-phosphatase activity
NI17_RS23630	COG1162	GTPase activity
NI17_RS23635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NI17_RS23650	COG2135	peptidase activity
NI17_RS23660	COG1595	DNA-templated transcription, initiation
NI17_RS23665	COG5662	AntiSigma factor
NI17_RS23670	COG2199	diguanylate cyclase activity
NI17_RS23670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NI17_RS23680	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NI17_RS23695	COG2188	Transcriptional regulator
NI17_RS23710	COG1597	lipid kinase activity
NI17_RS23725	COG2172	sigma factor antagonist activity
NI17_RS23735	COG1126	abc transporter atp-binding protein
NI17_RS23740	COG0765	amino acid transport
NI17_RS23745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NI17_RS23750	COG0281	malic enzyme
NI17_RS23775	COG0567	Dehydrogenase, E1 component
NI17_RS23775	COG0508	dehydrogenase complex catalyzes the overall conversion of
NI17_RS23780	COG1028	Short-chain dehydrogenase reductase Sdr
NI17_RS23800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NI17_RS23815	COG0438	transferase activity, transferring glycosyl groups
NI17_RS23830	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NI17_RS23850	COG1174	glycine betaine transport
NI17_RS23855	COG1174	glycine betaine transport
NI17_RS23875	COG0616	signal peptide processing
NI17_RS23890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NI17_RS23900	COG0366	Alpha amylase catalytic
NI17_RS23905	COG0366	Alpha amylase catalytic
NI17_RS23910	COG0058	SHG alpha-glucan phosphorylase activity
NI17_RS23920	COG1122	ATPase activity
NI17_RS23925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NI17_RS23940	COG2815	serine threonine protein kinase
NI17_RS23940	COG0515	serine threonine protein kinase
NI17_RS23950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NI17_RS23965	COG0482	sulfurtransferase activity
NI17_RS23980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NI17_RS23990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NI17_RS23995	COG0154	amidase activity
NI17_RS24010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NI17_RS24015	COG3300	MHYT domain
NI17_RS24015	COG5001	Diguanylate cyclase
NI17_RS24030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NI17_RS24035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NI17_RS24040	COG0473	3-isopropylmalate dehydrogenase activity
NI17_RS24045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NI17_RS24050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NI17_RS24135	COG3629	intracellular signal transduction
NI17_RS24135	COG3903	Transcriptional regulator
NI17_RS24220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NI17_RS24230	COG0305	Participates in initiation and elongation during chromosome replication
NI17_RS24320	COG1388	LysM domain
NI17_RS24320	COG0791	NLP P60 protein
NI17_RS24320	COG3103	Sh3 type 3 domain protein