locus-tag	class	description
CYL17_RS00010	COG1136	(ABC) transporter
CYL17_RS00025	COG2205	protein histidine kinase activity
CYL17_RS00030	COG0745	RESPONSE REGULATOR receiver
CYL17_RS00035	COG0579	oxidoreductase
CYL17_RS00055	COG1695	Transcriptional regulator
CYL17_RS00070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_RS00080	COG0667	Aldo Keto reductase
CYL17_RS00100	COG2252	PERMEase
CYL17_RS00120	COG1278	Cold shock
CYL17_RS00135	COG3973	AAA domain
CYL17_RS00140	COG0459	protein refolding
CYL17_RS00150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYL17_RS00180	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CYL17_RS00185	COG4608	Belongs to the ABC transporter superfamily
CYL17_RS00195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS00200	COG0601	transmembrane transport
CYL17_RS00215	COG1134	teichoic acid transport
CYL17_RS00220	COG1881	PFAM PEBP family protein
CYL17_RS00240	COG0416	fatty acid biosynthetic process
CYL17_RS00245	COG0018	arginyl-trna synthetase
CYL17_RS00255	COG1799	cell septum assembly
CYL17_RS00285	COG0243	molybdopterin cofactor binding
CYL17_RS00300	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS00315	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYL17_RS00320	COG0022	dehydrogenase e1 component
CYL17_RS00335	COG0477	Major facilitator Superfamily
CYL17_RS00345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYL17_RS00355	COG0047	phosphoribosylformylglycinamidine synthase activity
CYL17_RS00360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYL17_RS00385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CYL17_RS00410	COG1309	transcriptional regulator
CYL17_RS00425	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYL17_RS00430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CYL17_RS00455	COG0167	dihydroorotate dehydrogenase activity
CYL17_RS00510	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS00525	COG0730	response to heat
CYL17_RS00530	COG1797	cobyrinic acid a,c-diamide synthase activity
CYL17_RS00540	COG2205	protein histidine kinase activity
CYL17_RS00545	COG3189	MarR family transcriptional regulator
CYL17_RS00575	COG1302	Protein conserved in bacteria
CYL17_RS00630	COG2197	response regulator
CYL17_RS00645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CYL17_RS00660	COG2188	Transcriptional regulator
CYL17_RS00695	COG1937	Protein conserved in bacteria
CYL17_RS00700	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS00710	COG2181	nitrate reductase activity
CYL17_RS00710	COG0247	lactate metabolic process
CYL17_RS00715	COG1309	transcriptional regulator
CYL17_RS00720	COG2226	methyltransferase
CYL17_RS00725	COG1082	Xylose isomerase domain protein TIM barrel
CYL17_RS00730	COG2226	methyltransferase
CYL17_RS00735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CYL17_RS00745	COG1194	a g-specific adenine glycosylase
CYL17_RS00770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CYL17_RS00785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CYL17_RS00790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CYL17_RS00795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CYL17_RS00800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CYL17_RS00805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CYL17_RS00820	COG1690	Belongs to the RtcB family
CYL17_RS00825	COG1131	(ABC) transporter
CYL17_RS00850	COG1131	(ABC) transporter
CYL17_RS00865	COG2124	cytochrome p450
CYL17_RS00870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYL17_RS00875	COG0649	NAD binding
CYL17_RS00885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CYL17_RS00890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CYL17_RS00900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CYL17_RS00905	COG0302	gtp cyclohydrolase
CYL17_RS00910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYL17_RS00920	COG0037	tRNA processing
CYL17_RS00930	COG2027	D-alanyl-D-alanine carboxypeptidase
CYL17_RS00935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CYL17_RS00940	COG3883	PFAM NLP P60 protein
CYL17_RS00940	COG0791	NLP P60 protein
CYL17_RS00950	COG3268	Saccharopine dehydrogenase
CYL17_RS00970	COG0076	glutamate decarboxylase activity
CYL17_RS00975	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CYL17_RS01010	COG0470	DNA polymerase III
CYL17_RS01015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYL17_RS01020	COG1408	metallophosphoesterase
CYL17_RS01025	COG1754	DNA topoisomerase type I activity
CYL17_RS01025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYL17_RS01045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_RS01085	COG1131	(ABC) transporter
CYL17_RS01160	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_RS01170	COG1120	ATPase activity
CYL17_RS01175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_RS01200	COG2815	serine threonine protein kinase
CYL17_RS01200	COG0515	serine threonine protein kinase
CYL17_RS01220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYL17_RS01240	COG1482	cell wall glycoprotein biosynthetic process
CYL17_RS01250	COG1609	Transcriptional regulator
CYL17_RS01265	COG0515	serine threonine protein kinase
CYL17_RS01265	COG2815	serine threonine protein kinase
CYL17_RS01295	COG2890	protein-(glutamine-N5) methyltransferase activity
CYL17_RS01300	COG1309	transcriptional regulator
CYL17_RS01320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS01340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CYL17_RS01345	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CYL17_RS01385	COG0590	tRNA wobble adenosine to inosine editing
CYL17_RS01400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYL17_RS01420	COG2186	Transcriptional regulator
CYL17_RS01425	COG0592	DNA-directed DNA polymerase activity
CYL17_RS01430	COG2197	response regulator
CYL17_RS01440	COG1131	(ABC) transporter
CYL17_RS01455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CYL17_RS01465	COG1733	regulation of RNA biosynthetic process
CYL17_RS01470	COG0305	Participates in initiation and elongation during chromosome replication
CYL17_RS01475	COG0534	Mate efflux family protein
CYL17_RS01485	COG0765	amino acid transport
CYL17_RS01490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_RS01495	COG0359	binds to the 23S rRNA
CYL17_RS01500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CYL17_RS01510	COG0360	Binds together with S18 to 16S ribosomal RNA
CYL17_RS01535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_RS01550	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CYL17_RS01560	COG0617	tRNA 3'-terminal CCA addition
CYL17_RS01580	COG2815	serine threonine protein kinase
CYL17_RS01580	COG0515	serine threonine protein kinase
CYL17_RS01585	COG1595	DNA-templated transcription, initiation
CYL17_RS01595	COG0492	ferredoxin-NADP+ reductase activity
CYL17_RS01600	COG3118	belongs to the thioredoxin family
CYL17_RS01610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_RS01615	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYL17_RS01625	COG1695	Transcriptional regulator
CYL17_RS01650	COG1192	Involved in chromosome partitioning
CYL17_RS01655	COG0357	Ribosomal RNA small subunit methyltransferase G
CYL17_RS01665	COG0706	membrane insertase activity
CYL17_RS01675	COG0594	ribonuclease P activity
CYL17_RS01680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CYL17_RS01685	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CYL17_RS01690	COG0592	DNA-directed DNA polymerase activity
CYL17_RS01695	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CYL17_RS01700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYL17_RS01705	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CYL17_RS01710	COG0187	DNA topoisomerase II activity
CYL17_RS01715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYL17_RS01730	COG1742	UPF0060 membrane protein
CYL17_RS01755	COG2608	mercury ion transmembrane transporter activity
CYL17_RS01760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CYL17_RS01775	COG4604	ABC transporter, ATP-binding protein
CYL17_RS01780	COG4605	iron ion homeostasis
CYL17_RS01785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_RS01790	COG4607	ABC-type enterochelin transport system periplasmic component
CYL17_RS01815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYL17_RS01855	COG1215	transferase activity, transferring glycosyl groups
CYL17_RS01885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CYL17_RS01895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYL17_RS01915	COG1316	TRANSCRIPTIONal
CYL17_RS01940	COG1716	ATPase activity
CYL17_RS01955	COG0768	penicillin binding
CYL17_RS01960	COG0515	serine threonine protein kinase
CYL17_RS01965	COG0515	serine threonine protein kinase
CYL17_RS02010	COG0840	transmembrane signaling receptor activity
CYL17_RS02030	COG1175	transmembrane transport
CYL17_RS02035	COG1653	transport
CYL17_RS02050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CYL17_RS02055	COG1278	Cold shock
CYL17_RS02060	COG0561	phosphatase activity
CYL17_RS02140	COG0494	nUDIX hydrolase
CYL17_RS02150	COG2188	Transcriptional regulator
CYL17_RS02180	COG1203	CRISPR-associated helicase, Cas3
CYL17_RS02190	COG1518	maintenance of DNA repeat elements
CYL17_RS02195	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CYL17_RS02275	COG1799	cell septum assembly
CYL17_RS02280	COG1797	cobyrinic acid a,c-diamide synthase activity
CYL17_RS02350	COG1309	transcriptional regulator
CYL17_RS02360	COG0515	serine threonine protein kinase
CYL17_RS02365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CYL17_RS02395	COG3391	amine dehydrogenase activity
CYL17_RS02475	COG1595	DNA-templated transcription, initiation
CYL17_RS02485	COG1846	Transcriptional regulator
CYL17_RS02525	COG2814	Major facilitator Superfamily
CYL17_RS02535	COG3226	Transcriptional regulator
CYL17_RS02545	COG1322	Protein conserved in bacteria
CYL17_RS02550	COG1525	nuclease
CYL17_RS02555	COG1115	amino acid carrier protein
CYL17_RS02570	COG3708	Transcriptional regulator
CYL17_RS02570	COG2207	Transcriptional regulator
CYL17_RS02585	COG0633	Ferredoxin
CYL17_RS02585	COG0543	2 iron, 2 sulfur cluster binding
CYL17_RS02590	COG1151	hydroxylamine reductase activity
CYL17_RS02605	COG1522	sequence-specific DNA binding
CYL17_RS02640	COG1070	Carbohydrate kinase
CYL17_RS02660	COG2018	Roadblock/LC7 domain
CYL17_RS02715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYL17_RS02725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYL17_RS02730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CYL17_RS02735	COG0151	Belongs to the GarS family
CYL17_RS02745	COG1309	transcriptional regulator
CYL17_RS02760	COG0584	glycerophosphoryl diester phosphodiesterase
CYL17_RS02765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CYL17_RS02790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CYL17_RS02800	COG1432	Conserved Protein
CYL17_RS02810	COG5002	protein histidine kinase activity
CYL17_RS02810	COG0784	Response regulator, receiver
CYL17_RS02815	COG2770	Histidine kinase
CYL17_RS02815	COG2208	phosphoserine phosphatase activity
CYL17_RS02820	COG2226	methyltransferase
CYL17_RS02860	COG1408	metallophosphoesterase
CYL17_RS02870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_RS02880	COG0003	Pfam Anion-transporting ATPase
CYL17_RS02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYL17_RS02920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYL17_RS02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_RS02940	COG0596	Alpha beta hydrolase
CYL17_RS02950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_RS02995	COG1111	helicase
CYL17_RS02995	COG1205	dead DEAH box helicase
CYL17_RS03000	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_RS03010	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CYL17_RS03020	COG3830	Belongs to the UPF0237 family
CYL17_RS03020	COG0560	Phosphoserine phosphatase
CYL17_RS03030	COG4585	Histidine kinase
CYL17_RS03035	COG2197	response regulator
CYL17_RS03040	COG1119	ATPase activity
CYL17_RS03075	COG0753	catalase activity
CYL17_RS03090	COG1309	transcriptional regulator
CYL17_RS03110	COG0542	response to heat
CYL17_RS03115	COG0789	Transcriptional regulator
CYL17_RS03120	COG0484	heat shock protein binding
CYL17_RS03125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYL17_RS03130	COG0443	Heat shock 70 kDa protein
CYL17_RS03140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CYL17_RS03145	COG0123	including yeast histone deacetylase and acetoin utilization protein
CYL17_RS03185	COG1595	DNA-templated transcription, initiation
CYL17_RS03200	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CYL17_RS03205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CYL17_RS03210	COG0181	hydroxymethylbilane synthase activity
CYL17_RS03220	COG0113	porphobilinogen synthase activity
CYL17_RS03230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CYL17_RS03240	COG0406	alpha-ribazole phosphatase activity
CYL17_RS03245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYL17_RS03250	COG0785	Cytochrome C biogenesis protein
CYL17_RS03260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CYL17_RS03290	COG2226	methyltransferase
CYL17_RS03305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03315	COG0649	NAD binding
CYL17_RS03330	COG1034	ATP synthesis coupled electron transport
CYL17_RS03335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYL17_RS03340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03365	COG1007	ATP synthesis coupled electron transport
CYL17_RS03370	COG0142	geranyltranstransferase activity
CYL17_RS03385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYL17_RS03420	COG0697	spore germination
CYL17_RS03430	COG0444	Belongs to the ABC transporter superfamily
CYL17_RS03435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS03445	COG0747	negative chemotaxis
CYL17_RS03460	COG1013	pyruvate-flavodoxin oxidoreductase activity
CYL17_RS03465	COG0674	pyruvate-flavodoxin oxidoreductase activity
CYL17_RS03465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CYL17_RS03470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYL17_RS03495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYL17_RS03505	COG0713	ATP synthesis coupled electron transport
CYL17_RS03520	COG1007	ATP synthesis coupled electron transport
CYL17_RS03525	COG0501	Belongs to the peptidase M48B family
CYL17_RS03535	COG0765	amino acid transport
CYL17_RS03540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_RS03555	COG1666	GTP binding
CYL17_RS03620	COG0494	nUDIX hydrolase
CYL17_RS03665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYL17_RS03670	COG1247	-acetyltransferase
CYL17_RS03675	COG0640	Transcriptional regulator
CYL17_RS03705	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_RS03730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CYL17_RS03735	COG2030	dehydratase
CYL17_RS03745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CYL17_RS03750	COG2119	membrane
CYL17_RS03755	COG1672	PFAM Archaeal ATPase
CYL17_RS03755	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYL17_RS03765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYL17_RS03770	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS03775	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS03790	COG0321	lipoyl(octanoyl) transferase activity
CYL17_RS03800	COG0803	Belongs to the bacterial solute-binding protein 9 family
CYL17_RS03805	COG1121	(ABC) transporter
CYL17_RS03815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYL17_RS03855	COG0640	Transcriptional regulator
CYL17_RS03860	COG1902	pentaerythritol trinitrate reductase activity
CYL17_RS03865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS03885	COG3629	intracellular signal transduction
CYL17_RS03885	COG3903	Transcriptional regulator
CYL17_RS03890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CYL17_RS03895	COG3509	depolymerase
CYL17_RS03900	COG2856	Zn peptidase
CYL17_RS03925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYL17_RS03925	COG0517	IMP dehydrogenase activity
CYL17_RS03925	COG0617	tRNA 3'-terminal CCA addition
CYL17_RS03930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYL17_RS03935	COG1993	acr, cog1993
CYL17_RS03940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYL17_RS03980	COG1309	transcriptional regulator
CYL17_RS03990	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS04010	COG4326	sporulation control protein
CYL17_RS04015	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CYL17_RS04020	COG1309	transcriptional regulator
CYL17_RS04125	COG0183	Belongs to the thiolase family
CYL17_RS04130	COG0640	Transcriptional regulator
CYL17_RS04135	COG0402	S-adenosylhomocysteine deaminase activity
CYL17_RS04200	COG0717	Belongs to the dCTP deaminase family
CYL17_RS04215	COG0456	acetyltransferase
CYL17_RS04220	COG0737	Belongs to the 5'-nucleotidase family
CYL17_RS04225	COG0745	RESPONSE REGULATOR receiver
CYL17_RS04260	COG2897	thiosulfate sulfurtransferase activity
CYL17_RS04300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYL17_RS04305	COG3442	glutamine amidotransferase
CYL17_RS04315	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CYL17_RS04325	COG0735	belongs to the Fur family
CYL17_RS04330	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_RS04335	COG1366	Belongs to the anti-sigma-factor antagonist family
CYL17_RS04340	COG2172	sigma factor antagonist activity
CYL17_RS04350	COG2205	protein histidine kinase activity
CYL17_RS04350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYL17_RS04360	COG0354	folic acid binding
CYL17_RS04365	COG1490	D-aminoacyl-tRNA deacylase activity
CYL17_RS04380	COG0598	Magnesium transport protein CorA
CYL17_RS04400	COG0501	Belongs to the peptidase M48B family
CYL17_RS04425	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS04435	COG0588	phosphoglycerate mutase activity
CYL17_RS04445	COG5002	protein histidine kinase activity
CYL17_RS04460	COG1329	Transcriptional regulator
CYL17_RS04465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CYL17_RS04485	COG0215	cysteine-tRNA ligase activity
CYL17_RS04505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYL17_RS04520	COG0310	cobalt ion transport
CYL17_RS04530	COG1122	ATPase activity
CYL17_RS04540	COG1024	Enoyl-CoA hydratase
CYL17_RS04550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CYL17_RS04560	COG0259	pyridoxamine-phosphate oxidase activity
CYL17_RS04565	COG1573	uracil-dna glycosylase
CYL17_RS04585	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS04625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_RS04630	COG0436	Aminotransferase
CYL17_RS04650	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CYL17_RS04655	COG0081	regulation of translation
CYL17_RS04670	COG0222	ribosome binding
CYL17_RS04675	COG0085	RNA polymerase activity
CYL17_RS04680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CYL17_RS04685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYL17_RS04690	COG2124	cytochrome p450
CYL17_RS04695	COG2124	cytochrome p450
CYL17_RS04700	COG1309	transcriptional regulator
CYL17_RS04740	COG1473	amidohydrolase
CYL17_RS04745	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CYL17_RS04750	COG0049	tRNA binding
CYL17_RS04755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYL17_RS04765	COG0051	transcription antitermination factor activity, RNA binding
CYL17_RS04770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CYL17_RS04775	COG0088	Forms part of the polypeptide exit tunnel
CYL17_RS04780	COG0089	rRNA binding
CYL17_RS04785	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYL17_RS04790	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CYL17_RS04795	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CYL17_RS04800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CYL17_RS04805	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CYL17_RS04810	COG0255	Belongs to the universal ribosomal protein uL29 family
CYL17_RS04815	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CYL17_RS04820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CYL17_RS04825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CYL17_RS04830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CYL17_RS04835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CYL17_RS04840	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CYL17_RS04845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CYL17_RS04850	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CYL17_RS04855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CYL17_RS04860	COG1841	ribosomal large subunit assembly
CYL17_RS04865	COG0200	Binds to the 23S rRNA
CYL17_RS04875	COG0563	adenylate kinase activity
CYL17_RS04900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CYL17_RS04905	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CYL17_RS04910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYL17_RS04915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CYL17_RS04920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CYL17_RS04925	COG0202	RNA polymerase activity
CYL17_RS04930	COG0203	ribosomal protein L17
CYL17_RS04935	COG0101	tRNA pseudouridine synthase activity
CYL17_RS04955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CYL17_RS04960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CYL17_RS04965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_RS04975	COG1131	(ABC) transporter
CYL17_RS04990	COG1072	(Pantothenic acid kinase))
CYL17_RS04995	COG0736	holo-[acyl-carrier-protein] synthase activity
CYL17_RS05005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CYL17_RS05015	COG0802	atpase or kinase
CYL17_RS05035	COG0456	acetyltransferase
CYL17_RS05035	COG1214	PFAM Peptidase M22, glycoprotease
CYL17_RS05040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CYL17_RS05055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYL17_RS05060	COG0459	protein refolding
CYL17_RS05065	COG1595	DNA-templated transcription, initiation
CYL17_RS05080	COG0516	GMP reductase activity
CYL17_RS05085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CYL17_RS05090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYL17_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS05105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CYL17_RS05105	COG0519	Catalyzes the synthesis of GMP from XMP
CYL17_RS05115	COG0789	Transcriptional regulator
CYL17_RS05125	COG0726	polysaccharide deacetylase
CYL17_RS05135	COG0463	Glycosyl transferase, family 2
CYL17_RS05140	COG1216	Glycosyl transferase, family 2
CYL17_RS05145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CYL17_RS05150	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS05160	COG0457	Tetratricopeptide repeat
CYL17_RS05205	COG2197	response regulator
CYL17_RS05215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_RS05230	COG0045	succinate-CoA ligase (ADP-forming) activity
CYL17_RS05260	COG0138	bifunctional purine biosynthesis protein purh
CYL17_RS05265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CYL17_RS05275	COG0372	Belongs to the citrate synthase family
CYL17_RS05305	COG1253	flavin adenine dinucleotide binding
CYL17_RS05310	COG0180	Tryptophanyl-tRNA synthetase
CYL17_RS05320	COG1686	Belongs to the peptidase S11 family
CYL17_RS05330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_RS05335	COG1473	amidohydrolase
CYL17_RS05335	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYL17_RS05340	COG1744	ABC transporter substrate-binding protein PnrA-like
CYL17_RS05345	COG3845	ABC transporter
CYL17_RS05350	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS05355	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS05375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_RS05385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_RS05410	COG4770	biotin carboxylase activity
CYL17_RS05420	COG1674	ftsk spoiiie
CYL17_RS05445	COG1432	Conserved Protein
CYL17_RS05455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYL17_RS05460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CYL17_RS05475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CYL17_RS05485	COG2193	ferroxidase activity
CYL17_RS05490	COG0745	RESPONSE REGULATOR receiver
CYL17_RS05495	COG5002	protein histidine kinase activity
CYL17_RS05520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CYL17_RS05535	COG1285	pathogenesis
CYL17_RS05540	COG1316	TRANSCRIPTIONal
CYL17_RS05550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CYL17_RS05565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYL17_RS05570	COG0371	Dehydrogenase
CYL17_RS05590	COG3594	Acyltransferase
CYL17_RS05595	COG1316	TRANSCRIPTIONal
CYL17_RS05630	COG1271	oxidase subunit
CYL17_RS05635	COG1294	oxidase, subunit
CYL17_RS05640	COG4988	ABC transporter
CYL17_RS05645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CYL17_RS05660	COG2226	methyltransferase
CYL17_RS05680	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CYL17_RS05690	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CYL17_RS05690	COG0778	Nitroreductase
CYL17_RS05695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CYL17_RS05730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYL17_RS05735	COG2835	tetraacyldisaccharide 4'-kinase activity
CYL17_RS05765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYL17_RS05770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYL17_RS05800	COG0745	RESPONSE REGULATOR receiver
CYL17_RS05805	COG5002	protein histidine kinase activity
CYL17_RS05810	COG0823	Involved in the tonB-independent uptake of proteins
CYL17_RS05820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CYL17_RS05825	COG2197	response regulator
CYL17_RS05835	COG0653	protein targeting
CYL17_RS05850	COG3509	depolymerase
CYL17_RS05855	COG2188	Transcriptional regulator
CYL17_RS05860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYL17_RS05865	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_RS05870	COG1011	Hydrolase
CYL17_RS05885	COG0546	phosphoglycolate phosphatase activity
CYL17_RS05890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_RS05895	COG2902	Dehydrogenase
CYL17_RS05905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CYL17_RS05910	COG2884	Cell division ATP-binding protein ftsE
CYL17_RS05915	COG2177	Part of the ABC transporter FtsEX involved in
CYL17_RS05920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CYL17_RS05940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_RS05955	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS05970	COG4981	capsule polysaccharide biosynthetic process
CYL17_RS05980	COG0500	methyltransferase
CYL17_RS06005	COG0277	FAD linked oxidase domain protein
CYL17_RS06010	COG0300	oxidoreductase activity
CYL17_RS06050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CYL17_RS06055	COG0686	Belongs to the AlaDH PNT family
CYL17_RS06065	COG0789	Transcriptional regulator
CYL17_RS06070	COG0405	Gamma-glutamyltransferase
CYL17_RS06090	COG2814	Major facilitator Superfamily
CYL17_RS06110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYL17_RS06155	COG1653	transport
CYL17_RS06160	COG2273	Hydrolase Family 16
CYL17_RS06190	COG2208	phosphoserine phosphatase activity
CYL17_RS06190	COG2770	Histidine kinase
CYL17_RS06200	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYL17_RS06225	COG2271	Major facilitator Superfamily
CYL17_RS06245	COG2815	serine threonine protein kinase
CYL17_RS06245	COG0515	serine threonine protein kinase
CYL17_RS06280	COG0395	ABC-type sugar transport system, permease component
CYL17_RS06285	COG1175	transmembrane transport
CYL17_RS06290	COG1653	transport
CYL17_RS06295	COG1653	transport
CYL17_RS06305	COG1136	(ABC) transporter
CYL17_RS06315	COG0366	Alpha amylase catalytic
CYL17_RS06335	COG0019	diaminopimelate decarboxylase activity
CYL17_RS06340	COG0460	homoserine dehydrogenase
CYL17_RS06355	COG1215	transferase activity, transferring glycosyl groups
CYL17_RS06365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CYL17_RS06370	COG0083	homoserine kinase activity
CYL17_RS06380	COG0254	rRNA binding
CYL17_RS06385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CYL17_RS06390	COG2890	protein-(glutamine-N5) methyltransferase activity
CYL17_RS06420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYL17_RS06425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CYL17_RS06430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYL17_RS06435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CYL17_RS06440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CYL17_RS06445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CYL17_RS06450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CYL17_RS06465	COG4152	abc transporter atp-binding protein
CYL17_RS06470	COG1668	transmembrane transport
CYL17_RS06475	COG4585	Histidine kinase
CYL17_RS06480	COG2197	response regulator
CYL17_RS06500	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CYL17_RS06515	COG0596	Alpha beta hydrolase
CYL17_RS06530	COG0183	Belongs to the thiolase family
CYL17_RS06565	COG1678	Uncharacterized ACR, COG1678
CYL17_RS06575	COG0477	Major facilitator Superfamily
CYL17_RS06605	COG1335	isochorismatase
CYL17_RS06615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CYL17_RS06645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CYL17_RS06650	COG1234	tRNA 3'-trailer cleavage
CYL17_RS06655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CYL17_RS06660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CYL17_RS06675	COG1309	transcriptional regulator
CYL17_RS06690	COG1136	(ABC) transporter
CYL17_RS06690	COG0577	efflux transmembrane transporter activity
CYL17_RS06695	COG1136	(ABC) transporter
CYL17_RS06695	COG0577	efflux transmembrane transporter activity
CYL17_RS06700	COG2197	response regulator
CYL17_RS06705	COG4585	Histidine kinase
CYL17_RS06750	COG0509	glycine decarboxylation via glycine cleavage system
CYL17_RS06755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CYL17_RS06770	COG4221	oxidoreductase activity
CYL17_RS06780	COG1228	amidohydrolase
CYL17_RS06805	COG2018	Roadblock/LC7 domain
CYL17_RS06820	COG5002	protein histidine kinase activity
CYL17_RS06825	COG2018	Roadblock/LC7 domain
CYL17_RS06845	COG0228	four-way junction DNA binding
CYL17_RS06850	COG1837	Belongs to the UPF0109 family
CYL17_RS06855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CYL17_RS06860	COG0336	Belongs to the RNA methyltransferase TrmD family
CYL17_RS06865	COG0335	large ribosomal subunit rRNA binding
CYL17_RS06870	COG0681	Belongs to the peptidase S26 family
CYL17_RS06880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYL17_RS06910	COG0792	nuclease activity
CYL17_RS06920	COG0052	Belongs to the universal ribosomal protein uS2 family
CYL17_RS06925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CYL17_RS06930	COG0528	UMP kinase activity
CYL17_RS06935	COG0233	cytoplasmic translational termination
CYL17_RS06940	COG0575	Belongs to the CDS family
CYL17_RS06950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYL17_RS06960	COG3835	regulator
CYL17_RS06985	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS06990	COG3842	ATPase activity
CYL17_RS07000	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYL17_RS07005	COG1177	transmembrane transport
CYL17_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYL17_RS07015	COG0640	Transcriptional regulator
CYL17_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS07055	COG3469	chitinase activity
CYL17_RS07065	COG0628	permease
CYL17_RS07105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_RS07115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CYL17_RS07140	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS07160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CYL17_RS07175	COG1309	transcriptional regulator
CYL17_RS07180	COG2409	Drug exporters of the RND superfamily
CYL17_RS07210	COG2188	Transcriptional regulator
CYL17_RS07230	COG0442	prolyl-tRNA aminoacylation
CYL17_RS07245	COG0779	Required for maturation of 30S ribosomal subunits
CYL17_RS07260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CYL17_RS07270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CYL17_RS07275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYL17_RS07280	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CYL17_RS07290	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CYL17_RS07295	COG1185	polyribonucleotide nucleotidyltransferase activity
CYL17_RS07300	COG0612	Peptidase, M16
CYL17_RS07305	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYL17_RS07325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_RS07335	COG2188	Transcriptional regulator
CYL17_RS07340	COG2003	Belongs to the UPF0758 family
CYL17_RS07355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYL17_RS07360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CYL17_RS07370	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_RS07375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYL17_RS07380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_RS07390	COG3866	Pectate lyase
CYL17_RS07400	COG0395	ABC-type sugar transport system, permease component
CYL17_RS07410	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_RS07415	COG1414	Transcriptional regulator
CYL17_RS07420	COG1674	ftsk spoiiie
CYL17_RS07430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYL17_RS07440	COG1058	Belongs to the CinA family
CYL17_RS07440	COG1546	Belongs to the CinA family
CYL17_RS07445	COG1396	sequence-specific DNA binding
CYL17_RS07450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYL17_RS07460	COG1940	carbohydrate kinase activity
CYL17_RS07465	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_RS07470	COG0395	ABC-type sugar transport system, permease component
CYL17_RS07475	COG1175	transmembrane transport
CYL17_RS07520	COG1201	RNA secondary structure unwinding
CYL17_RS07530	COG4152	abc transporter atp-binding protein
CYL17_RS07535	COG1668	transmembrane transport
CYL17_RS07545	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CYL17_RS07550	COG2137	regulation of response to DNA damage stimulus
CYL17_RS07555	COG1418	mRNA catabolic process
CYL17_RS07575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYL17_RS07585	COG1234	tRNA 3'-trailer cleavage
CYL17_RS07595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CYL17_RS07600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CYL17_RS07625	COG0247	lactate metabolic process
CYL17_RS07630	COG0277	FAD linked oxidase domain protein
CYL17_RS07635	COG0277	FAD linked oxidase domain protein
CYL17_RS07640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CYL17_RS07650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CYL17_RS07660	COG1596	polysaccharide export
CYL17_RS07660	COG1555	photosystem II stabilization
CYL17_RS07675	COG0268	Binds directly to 16S ribosomal RNA
CYL17_RS07680	COG0481	GTPase activity
CYL17_RS07685	COG2258	MOSC domain
CYL17_RS07700	COG1420	regulation of RNA biosynthetic process
CYL17_RS07705	COG0484	heat shock protein binding
CYL17_RS07725	COG0537	adenosine 5'-monophosphoramidase activity
CYL17_RS07735	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CYL17_RS07755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CYL17_RS07765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYL17_RS07780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_RS07785	COG1834	amidinotransferase
CYL17_RS07790	COG1522	sequence-specific DNA binding
CYL17_RS07795	COG0583	DNA-binding transcription factor activity
CYL17_RS07820	COG1381	Involved in DNA repair and RecF pathway recombination
CYL17_RS07825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYL17_RS07850	COG0423	glycine-tRNA ligase activity
CYL17_RS07860	COG0574	Belongs to the PEP-utilizing enzyme family
CYL17_RS07860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYL17_RS07865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CYL17_RS07875	COG0358	DNA primase activity
CYL17_RS07880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_RS07900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CYL17_RS07905	COG2188	Transcriptional regulator
CYL17_RS07915	COG1129	ABC transporter
CYL17_RS07935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CYL17_RS07940	COG1070	Carbohydrate kinase
CYL17_RS07970	COG1131	(ABC) transporter
CYL17_RS07975	COG2188	Transcriptional regulator
CYL17_RS07985	COG1309	transcriptional regulator
CYL17_RS08005	COG0730	response to heat
CYL17_RS08010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYL17_RS08015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYL17_RS08045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CYL17_RS08055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYL17_RS08085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CYL17_RS08090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_RS08095	COG1120	ATPase activity
CYL17_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS08130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CYL17_RS08175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CYL17_RS08185	COG0477	Major facilitator Superfamily
CYL17_RS08190	COG1309	transcriptional regulator
CYL17_RS08195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYL17_RS08195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CYL17_RS08205	COG2814	Major facilitator Superfamily
CYL17_RS08215	COG0174	glutamine synthetase
CYL17_RS08225	COG0505	Belongs to the CarA family
CYL17_RS08230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CYL17_RS08245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYL17_RS08255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CYL17_RS08260	COG0321	lipoyl(octanoyl) transferase activity
CYL17_RS08265	COG3340	Belongs to the peptidase S51 family
CYL17_RS08275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYL17_RS08280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYL17_RS08285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYL17_RS08300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CYL17_RS08315	COG0667	Aldo Keto reductase
CYL17_RS08335	COG0501	Belongs to the peptidase M48B family
CYL17_RS08345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CYL17_RS08355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_RS08370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CYL17_RS08375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYL17_RS08385	COG1376	ErfK ybiS ycfS ynhG family protein
CYL17_RS08390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CYL17_RS08395	COG0723	plastoquinol--plastocyanin reductase activity
CYL17_RS08405	COG1845	cytochrome c oxidase, subunit III
CYL17_RS08415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYL17_RS08440	COG0791	NLP P60 protein
CYL17_RS08440	COG1388	LysM domain
CYL17_RS08465	COG1940	carbohydrate kinase activity
CYL17_RS08490	COG0204	Acyl-transferase
CYL17_RS08500	COG2040	homocysteine
CYL17_RS08535	COG4521	taurine ABC transporter
CYL17_RS08540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS08555	COG0205	6-phosphofructokinase activity
CYL17_RS08560	COG0301	tRNA thio-modification
CYL17_RS08565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CYL17_RS08570	COG3275	phosphorelay sensor kinase activity
CYL17_RS08575	COG3279	Response regulator of the LytR AlgR family
CYL17_RS08580	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CYL17_RS08610	COG2815	serine threonine protein kinase
CYL17_RS08610	COG0515	serine threonine protein kinase
CYL17_RS08615	COG2022	thiamine diphosphate biosynthetic process
CYL17_RS08625	COG2022	thiamine diphosphate biosynthetic process
CYL17_RS08625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYL17_RS08640	COG0352	thiamine-phosphate diphosphorylase activity
CYL17_RS08645	COG0142	geranyltranstransferase activity
CYL17_RS08665	COG3409	Peptidoglycan-binding domain 1 protein
CYL17_RS08665	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYL17_RS08680	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CYL17_RS08685	COG0540	Belongs to the ATCase OTCase family
CYL17_RS08690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYL17_RS08695	COG0505	Belongs to the CarA family
CYL17_RS08700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYL17_RS08705	COG0543	2 iron, 2 sulfur cluster binding
CYL17_RS08710	COG0167	dihydroorotate dehydrogenase activity
CYL17_RS08715	COG0284	orotidine-5'-phosphate decarboxylase activity
CYL17_RS08725	COG0194	GDP metabolic process
CYL17_RS08730	COG1758	RNA polymerase activity
CYL17_RS08740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CYL17_RS08760	COG0242	peptide deformylase activity
CYL17_RS08765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CYL17_RS08775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYL17_RS08780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYL17_RS08780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYL17_RS08790	COG3201	nicotinamide mononucleotide transporter
CYL17_RS08795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYL17_RS08795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYL17_RS08800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CYL17_RS08815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYL17_RS08820	COG1116	anion transmembrane transporter activity
CYL17_RS08825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_RS08840	COG0542	response to heat
CYL17_RS08865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS08875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYL17_RS08880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYL17_RS08890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CYL17_RS08900	COG1305	Transglutaminase-like
CYL17_RS08910	COG0714	Associated with various cellular activities
CYL17_RS08915	COG2001	Belongs to the MraZ family
CYL17_RS08920	COG0275	rRNA processing
CYL17_RS08930	COG0768	penicillin binding
CYL17_RS08935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CYL17_RS08945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CYL17_RS08950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYL17_RS08960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CYL17_RS08965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CYL17_RS08970	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CYL17_RS08975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CYL17_RS08985	COG1799	cell septum assembly
CYL17_RS09005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CYL17_RS09010	COG1872	DUF167
CYL17_RS09020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYL17_RS09035	COG0210	DNA helicase
CYL17_RS09040	COG0515	serine threonine protein kinase
CYL17_RS09050	COG0587	DNA-directed DNA polymerase activity
CYL17_RS09060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYL17_RS09070	COG0154	amidase activity
CYL17_RS09075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CYL17_RS09080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CYL17_RS09090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CYL17_RS09095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYL17_RS09100	COG0131	Imidazoleglycerol-phosphate dehydratase
CYL17_RS09105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CYL17_RS09110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CYL17_RS09115	COG0251	oxidation-reduction process
CYL17_RS09120	COG0107	imidazoleglycerol-phosphate synthase activity
CYL17_RS09140	COG1132	(ABC) transporter
CYL17_RS09145	COG1132	(ABC) transporter
CYL17_RS09150	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CYL17_RS09170	COG0134	indole-3-glycerol-phosphate synthase activity
CYL17_RS09175	COG0133	tryptophan synthase activity
CYL17_RS09180	COG0159	tryptophan synthase activity
CYL17_RS09195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYL17_RS09205	COG0070	glutamate synthase
CYL17_RS09205	COG0067	glutamate synthase
CYL17_RS09205	COG0069	glutamate synthase activity
CYL17_RS09235	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS09240	COG0411	ABC transporter
CYL17_RS09265	COG0683	leucine binding
CYL17_RS09290	COG2050	protein possibly involved in aromatic compounds catabolism
CYL17_RS09305	COG0539	negative regulation of cytoplasmic translation
CYL17_RS09315	COG0237	dephospho-CoA kinase activity
CYL17_RS09340	COG0556	nucleotide-excision repair
CYL17_RS09345	COG0110	maltose O-acetyltransferase activity
CYL17_RS09350	COG0504	CTP synthase activity
CYL17_RS09370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CYL17_RS09375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CYL17_RS09395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CYL17_RS09400	COG1160	GTP binding
CYL17_RS09405	COG0477	Major facilitator Superfamily
CYL17_RS09460	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS09465	COG0506	proline dehydrogenase activity
CYL17_RS09475	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS09485	COG1252	NADH dehydrogenase
CYL17_RS09535	COG2188	Transcriptional regulator
CYL17_RS09555	COG3693	PFAM glycoside hydrolase, family 10
CYL17_RS09560	COG4733	cellulase activity
CYL17_RS09560	COG5297	Belongs to the glycosyl hydrolase family 6
CYL17_RS09595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CYL17_RS09600	COG1518	maintenance of DNA repeat elements
CYL17_RS09615	COG1857	crispr-associated protein
CYL17_RS09640	COG0443	Heat shock 70 kDa protein
CYL17_RS09660	COG0515	serine threonine protein kinase
CYL17_RS09690	COG0531	amino acid
CYL17_RS09700	COG0804	urea catabolic process
CYL17_RS09705	COG0832	Belongs to the urease beta subunit family
CYL17_RS09705	COG0831	urea catabolic process
CYL17_RS09710	COG1609	Transcriptional regulator
CYL17_RS09715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYL17_RS09720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYL17_RS09725	COG1116	anion transmembrane transporter activity
CYL17_RS09730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS09735	COG3693	PFAM glycoside hydrolase, family 10
CYL17_RS09745	COG1653	transport
CYL17_RS09750	COG0395	ABC-type sugar transport system, permease component
CYL17_RS09755	COG4209	transmembrane transport
CYL17_RS09795	COG1966	Carbon starvation protein
CYL17_RS09810	COG2323	membrane
CYL17_RS09830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYL17_RS09865	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS09875	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS09880	COG3842	ATPase activity
CYL17_RS09885	COG1177	transmembrane transport
CYL17_RS09890	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYL17_RS09905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS09910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS09915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS09920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS09925	COG2855	membrane
CYL17_RS09945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS09960	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS09975	COG0431	NADPH-dependent FMN reductase
CYL17_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS09995	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS10010	COG0477	Major facilitator Superfamily
CYL17_RS10035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYL17_RS10035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CYL17_RS10035	COG1703	isobutyryl-CoA mutase activity
CYL17_RS10040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CYL17_RS10045	COG2197	response regulator
CYL17_RS10050	COG1120	ATPase activity
CYL17_RS10055	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_RS10060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYL17_RS10085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYL17_RS10090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_RS10090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_RS10110	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS10115	COG1309	transcriptional regulator
CYL17_RS10135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CYL17_RS10190	COG2217	Heavy metal translocating P-type atpase
CYL17_RS10195	COG4109	DRTGG domain
CYL17_RS10210	COG2132	Multicopper oxidase
CYL17_RS10235	COG2205	protein histidine kinase activity
CYL17_RS10250	COG2847	Copper chaperone PCu(A)C
CYL17_RS10265	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_RS10270	COG1737	Transcriptional regulator
CYL17_RS10285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS10295	COG4608	Belongs to the ABC transporter superfamily
CYL17_RS10305	COG3876	Protein conserved in bacteria
CYL17_RS10310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYL17_RS10315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYL17_RS10340	COG1515	deoxyribonuclease V activity
CYL17_RS10345	COG0435	Glutathione S-transferase
CYL17_RS10385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CYL17_RS10390	COG2183	response to ionizing radiation
CYL17_RS10410	COG0772	Belongs to the SEDS family
CYL17_RS10415	COG0768	penicillin binding
CYL17_RS10420	COG1792	Involved in formation and maintenance of cell shape
CYL17_RS10450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CYL17_RS10455	COG1716	ATPase activity
CYL17_RS10475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYL17_RS10475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYL17_RS10525	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CYL17_RS10530	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CYL17_RS10540	COG2188	Transcriptional regulator
CYL17_RS10560	COG1132	(ABC) transporter
CYL17_RS10565	COG4988	ABC transporter
CYL17_RS10570	COG1739	Uncharacterized protein family UPF0029
CYL17_RS10575	COG1169	isochorismate synthase
CYL17_RS10590	COG2197	response regulator
CYL17_RS10595	COG4585	Histidine kinase
CYL17_RS10605	COG1131	(ABC) transporter
CYL17_RS10610	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS10635	COG2261	transglycosylase associated protein
CYL17_RS10645	COG0697	spore germination
CYL17_RS10685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYL17_RS10690	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS10695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYL17_RS10710	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS10725	COG0475	glutathione-regulated potassium exporter activity
CYL17_RS10750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CYL17_RS10755	COG1376	ErfK ybiS ycfS ynhG family protein
CYL17_RS10775	COG2076	Multidrug Resistance protein
CYL17_RS10780	COG1309	transcriptional regulator
CYL17_RS10785	COG0842	Transport permease protein
CYL17_RS10795	COG1131	(ABC) transporter
CYL17_RS10805	COG3290	protein histidine kinase activity
CYL17_RS10810	COG4565	transcriptional regulatory protein
CYL17_RS10820	COG2197	response regulator
CYL17_RS10835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_RS10840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_RS10860	COG4974	Belongs to the 'phage' integrase family
CYL17_RS10865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CYL17_RS10875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYL17_RS10880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CYL17_RS10900	COG1280	lysine exporter protein (LysE YggA)
CYL17_RS10910	COG2223	nitrite transmembrane transporter activity
CYL17_RS10925	COG0714	Associated with various cellular activities
CYL17_RS10940	COG2813	Specifically methylates the guanine in position
CYL17_RS10945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYL17_RS10950	COG0584	glycerophosphoryl diester phosphodiesterase
CYL17_RS10965	COG0583	DNA-binding transcription factor activity
CYL17_RS10970	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS10985	COG0463	Glycosyl transferase, family 2
CYL17_RS11015	COG1522	sequence-specific DNA binding
CYL17_RS11020	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS11035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYL17_RS11050	COG0805	protein transport
CYL17_RS11055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYL17_RS11080	COG0545	Peptidyl-prolyl cis-trans isomerase
CYL17_RS11085	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_RS11095	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_RS11100	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CYL17_RS11115	COG4122	O-methyltransferase activity
CYL17_RS11125	COG1222	aaa ATPase
CYL17_RS11135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_RS11145	COG0517	IMP dehydrogenase activity
CYL17_RS11145	COG1994	Peptidase M50
CYL17_RS11155	COG4585	Histidine kinase
CYL17_RS11160	COG2197	response regulator
CYL17_RS11165	COG4608	Belongs to the ABC transporter superfamily
CYL17_RS11170	COG0444	Belongs to the ABC transporter superfamily
CYL17_RS11185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS11195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYL17_RS11200	COG0646	methionine synthase
CYL17_RS11200	COG1410	methionine synthase
CYL17_RS11210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYL17_RS11230	COG0543	2 iron, 2 sulfur cluster binding
CYL17_RS11245	COG0463	Glycosyl transferase, family 2
CYL17_RS11330	COG0366	Alpha amylase catalytic
CYL17_RS11335	COG3833	ABC-type maltose transport systems, permease component
CYL17_RS11350	COG3842	ATPase activity
CYL17_RS11360	COG2205	protein histidine kinase activity
CYL17_RS11365	COG3119	arylsulfatase activity
CYL17_RS11375	COG1175	transmembrane transport
CYL17_RS11380	COG0395	ABC-type sugar transport system, permease component
CYL17_RS11385	COG2723	6-phospho-beta-galactosidase activity
CYL17_RS11395	COG2723	6-phospho-beta-galactosidase activity
CYL17_RS11400	COG2017	converts alpha-aldose to the beta-anomer
CYL17_RS11405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_RS11410	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CYL17_RS11420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYL17_RS11425	COG0589	response to stress
CYL17_RS11435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYL17_RS11450	COG2011	ABC-type metal ion transport system permease component
CYL17_RS11455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CYL17_RS11465	COG3540	Alkaline phosphatase
CYL17_RS11485	COG0672	)-iron permease
CYL17_RS11495	COG2837	iron assimilation
CYL17_RS11525	COG4133	protoheme IX ABC transporter activity
CYL17_RS11575	COG0215	cysteine-tRNA ligase activity
CYL17_RS11600	COG1968	undecaprenyl-diphosphatase activity
CYL17_RS11605	COG0667	Aldo Keto reductase
CYL17_RS11615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CYL17_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS11635	COG3360	Dodecin
CYL17_RS11645	COG0746	molybdenum cofactor guanylyltransferase activity
CYL17_RS11650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CYL17_RS11685	COG3104	oligopeptide transport
CYL17_RS11690	COG3387	PFAM Glycoside hydrolase 15-related
CYL17_RS11695	COG1619	proteins homologs of microcin C7 resistance protein MccF
CYL17_RS11705	COG1132	(ABC) transporter
CYL17_RS11720	COG0488	(ABC) transporter
CYL17_RS11730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CYL17_RS11735	COG0140	phosphoribosyl-ATP diphosphatase activity
CYL17_RS11740	COG3458	cephalosporin-C deacetylase activity
CYL17_RS11745	COG2151	metal-sulfur cluster biosynthetic enzyme
CYL17_RS11750	COG0822	iron-sulfur transferase activity
CYL17_RS11755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYL17_RS11760	COG0396	ATPase activity
CYL17_RS11765	COG2146	nitrite reductase [NAD(P)H] activity
CYL17_RS11770	COG0719	Fe-S assembly protein
CYL17_RS11785	COG1131	(ABC) transporter
CYL17_RS11795	COG5006	permease, DMT superfamily
CYL17_RS11810	COG0109	protoheme IX farnesyltransferase activity
CYL17_RS11820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYL17_RS11825	COG0166	Belongs to the GPI family
CYL17_RS11840	COG0363	glucosamine-6-phosphate deaminase activity
CYL17_RS11845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYL17_RS11845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_RS11850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CYL17_RS11865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CYL17_RS11875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CYL17_RS11880	COG1481	regulation of sporulation
CYL17_RS11890	COG1660	Displays ATPase and GTPase activities
CYL17_RS11895	COG0322	excinuclease ABC activity
CYL17_RS11905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYL17_RS11915	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_RS11930	COG0688	phosphatidylethanolamine metabolic process
CYL17_RS11940	COG0297	glycogen (starch) synthase activity
CYL17_RS11965	COG0497	DNA recombination
CYL17_RS11970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CYL17_RS11990	COG0647	UMP catabolic process
CYL17_RS12015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYL17_RS12020	COG3401	FG-GAP repeat protein
CYL17_RS12025	COG2094	Belongs to the DNA glycosylase MPG family
CYL17_RS12030	COG0165	Argininosuccinate lyase
CYL17_RS12035	COG0137	argininosuccinate synthase activity
CYL17_RS12040	COG1438	arginine binding
CYL17_RS12045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CYL17_RS12050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYL17_RS12055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CYL17_RS12060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CYL17_RS12065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CYL17_RS12070	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS12090	COG0072	phenylalanine-tRNA ligase activity
CYL17_RS12090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYL17_RS12095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CYL17_RS12100	COG5002	protein histidine kinase activity
CYL17_RS12105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYL17_RS12110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CYL17_RS12120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CYL17_RS12125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CYL17_RS12130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CYL17_RS12140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CYL17_RS12145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CYL17_RS12170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYL17_RS12175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CYL17_RS12180	COG0124	histidyl-tRNA synthetase
CYL17_RS12190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYL17_RS12195	COG1196	nuclear chromosome segregation
CYL17_RS12200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CYL17_RS12205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYL17_RS12210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_RS12215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYL17_RS12220	COG1862	Preprotein translocase
CYL17_RS12225	COG2255	four-way junction helicase activity
CYL17_RS12230	COG0632	four-way junction helicase activity
CYL17_RS12235	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CYL17_RS12240	COG0217	transcriptional regulatory protein
CYL17_RS12245	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CYL17_RS12255	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CYL17_RS12270	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS12275	COG1560	Kdo2-lipid A biosynthetic process
CYL17_RS12280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CYL17_RS12290	COG1649	PFAM Uncharacterised BCR, COG1649
CYL17_RS12300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CYL17_RS12305	COG0667	Aldo Keto reductase
CYL17_RS12325	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS12330	COG2197	response regulator
CYL17_RS12340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CYL17_RS12350	COG1733	regulation of RNA biosynthetic process
CYL17_RS12355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CYL17_RS12360	COG1024	Enoyl-CoA hydratase
CYL17_RS12365	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS12370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CYL17_RS12395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYL17_RS12400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CYL17_RS12400	COG0512	Glutamine amidotransferase of anthranilate synthase
CYL17_RS12405	COG0583	DNA-binding transcription factor activity
CYL17_RS12415	COG2986	histidine ammonia-lyase
CYL17_RS12440	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYL17_RS12445	COG0477	Major facilitator Superfamily
CYL17_RS12450	COG1309	transcriptional regulator
CYL17_RS12465	COG3851	Histidine kinase
CYL17_RS12490	COG2124	cytochrome p450
CYL17_RS12500	COG0297	glycogen (starch) synthase activity
CYL17_RS12505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYL17_RS12515	COG1024	Enoyl-CoA hydratase
CYL17_RS12525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYL17_RS12555	COG0243	molybdopterin cofactor binding
CYL17_RS12570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYL17_RS12575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CYL17_RS12575	COG1796	DNA polymerase
CYL17_RS12590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYL17_RS12600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYL17_RS12610	COG3279	Response regulator of the LytR AlgR family
CYL17_RS12615	COG3275	phosphorelay sensor kinase activity
CYL17_RS12650	COG1597	lipid kinase activity
CYL17_RS12660	COG0277	FAD linked oxidase domain protein
CYL17_RS12665	COG1024	Enoyl-CoA hydratase
CYL17_RS12680	COG2313	pseudouridylate synthase activity
CYL17_RS12700	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS12715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CYL17_RS12725	COG0022	dehydrogenase e1 component
CYL17_RS12770	COG0419	ATPase involved in DNA repair
CYL17_RS12775	COG0420	3'-5' exonuclease activity
CYL17_RS12785	COG1316	TRANSCRIPTIONal
CYL17_RS12790	COG4948	Mandelate Racemase Muconate Lactonizing
CYL17_RS12795	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CYL17_RS12805	COG0714	Associated with various cellular activities
CYL17_RS12820	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS12830	COG1741	Belongs to the pirin family
CYL17_RS12855	COG3842	ATPase activity
CYL17_RS12900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CYL17_RS12905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CYL17_RS12910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CYL17_RS12915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CYL17_RS12935	COG0549	Belongs to the carbamate kinase family
CYL17_RS12940	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_RS12945	COG0450	alkyl hydroperoxide reductase
CYL17_RS12960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYL17_RS13020	COG2233	PERMEase
CYL17_RS13035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CYL17_RS13040	COG1304	FMN binding
CYL17_RS13045	COG0515	serine threonine protein kinase
CYL17_RS13045	COG2815	serine threonine protein kinase
CYL17_RS13055	COG0277	FAD linked oxidase domain protein
CYL17_RS13075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CYL17_RS13080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CYL17_RS13090	COG0175	sulfate reduction
CYL17_RS13115	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS13140	COG1793	dna ligase
CYL17_RS13155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYL17_RS13165	COG3253	May function as heme-dependent peroxidase
CYL17_RS13170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CYL17_RS13180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CYL17_RS13190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CYL17_RS13195	COG0183	Belongs to the thiolase family
CYL17_RS13205	COG0531	amino acid
CYL17_RS13210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CYL17_RS13220	COG4214	carbohydrate transport
CYL17_RS13230	COG4213	ABC transporter substrate-binding protein
CYL17_RS13240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CYL17_RS13275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYL17_RS13280	COG0531	amino acid
CYL17_RS13285	COG0569	domain protein
CYL17_RS13310	COG0756	dUTP diphosphatase activity
CYL17_RS13320	COG0525	valine-tRNA ligase activity
CYL17_RS13330	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CYL17_RS13345	COG2205	protein histidine kinase activity
CYL17_RS13350	COG0745	RESPONSE REGULATOR receiver
CYL17_RS13365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYL17_RS13370	COG0739	heme binding
CYL17_RS13400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_RS13425	COG1579	Zn-ribbon protein possibly nucleic acid-binding
CYL17_RS13430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CYL17_RS13435	COG2205	protein histidine kinase activity
CYL17_RS13450	COG0300	oxidoreductase activity
CYL17_RS13460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CYL17_RS13465	COG1609	Transcriptional regulator
CYL17_RS13510	COG1643	Atp-dependent helicase
CYL17_RS13515	COG0745	RESPONSE REGULATOR receiver
CYL17_RS13555	COG1404	Belongs to the peptidase S8 family
CYL17_RS13570	COG3173	Aminoglycoside phosphotransferase
CYL17_RS13595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYL17_RS13660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CYL17_RS13675	COG0754	glutathionylspermidine amidase activity
CYL17_RS13680	COG3766	membrane
CYL17_RS13710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYL17_RS13715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYL17_RS13785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_RS13795	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYL17_RS13830	COG0187	DNA topoisomerase II activity
CYL17_RS13845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_RS13845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYL17_RS13850	COG5001	Diguanylate cyclase
CYL17_RS13860	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CYL17_RS13880	COG1609	Transcriptional regulator
CYL17_RS13885	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_RS13890	COG1940	carbohydrate kinase activity
CYL17_RS13905	COG2815	serine threonine protein kinase
CYL17_RS13905	COG0515	serine threonine protein kinase
CYL17_RS13910	COG0515	serine threonine protein kinase
CYL17_RS13915	COG1472	Belongs to the glycosyl hydrolase 3 family
CYL17_RS13920	COG0395	ABC-type sugar transport system, permease component
CYL17_RS13935	COG1501	Belongs to the glycosyl hydrolase 31 family
CYL17_RS13975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CYL17_RS13980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CYL17_RS13985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CYL17_RS13990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CYL17_RS13995	COG0495	leucyl-tRNA aminoacylation
CYL17_RS14010	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS14015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYL17_RS14065	COG0424	maF-like protein
CYL17_RS14080	COG1492	cobalamin metabolic process
CYL17_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS14120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CYL17_RS14125	COG0501	Belongs to the peptidase M48B family
CYL17_RS14135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CYL17_RS14140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CYL17_RS14145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYL17_RS14150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CYL17_RS14155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CYL17_RS14160	COG1530	ribonuclease E activity
CYL17_RS14175	COG0772	Belongs to the SEDS family
CYL17_RS14180	COG0768	penicillin binding
CYL17_RS14195	COG1077	Cell shape determining protein MreB Mrl
CYL17_RS14200	COG0105	UTP biosynthetic process
CYL17_RS14215	COG0285	dihydrofolate synthase activity
CYL17_RS14225	COG0525	valine-tRNA ligase activity
CYL17_RS14230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYL17_RS14235	COG0740	serine-type endopeptidase activity
CYL17_RS14240	COG0740	serine-type endopeptidase activity
CYL17_RS14245	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYL17_RS14265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CYL17_RS14300	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS14310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYL17_RS14335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CYL17_RS14345	COG1028	Short-chain dehydrogenase reductase Sdr
CYL17_RS14365	COG0750	zinc metalloprotease
CYL17_RS14380	COG0242	peptide deformylase activity
CYL17_RS14400	COG0154	amidase activity
CYL17_RS14410	COG0129	dihydroxy-acid dehydratase activity
CYL17_RS14435	COG1505	serine-type exopeptidase activity
CYL17_RS14465	COG0668	transmembrane transport
CYL17_RS14510	COG0629	single-stranded DNA binding
CYL17_RS14525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CYL17_RS14525	COG1648	precorrin-2 dehydrogenase activity
CYL17_RS14530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CYL17_RS14555	COG0583	DNA-binding transcription factor activity
CYL17_RS14570	COG0587	DNA-directed DNA polymerase activity
CYL17_RS14585	COG0574	Belongs to the PEP-utilizing enzyme family
CYL17_RS14585	COG3848	Pyruvate phosphate dikinase
CYL17_RS14600	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CYL17_RS14625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_RS14630	COG1609	Transcriptional regulator
CYL17_RS14645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS14665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_RS14670	COG4266	Belongs to the allantoicase family
CYL17_RS14675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYL17_RS14680	COG1929	Belongs to the glycerate kinase type-1 family
CYL17_RS14725	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CYL17_RS14730	COG1984	allophanate hydrolase subunit 2
CYL17_RS14740	COG1760	l-serine dehydratase
CYL17_RS14750	COG2723	6-phospho-beta-galactosidase activity
CYL17_RS14755	COG1012	belongs to the aldehyde dehydrogenase family
CYL17_RS14760	COG0028	Belongs to the TPP enzyme family
CYL17_RS14765	COG0477	Major facilitator Superfamily
CYL17_RS14775	COG0804	urea catabolic process
CYL17_RS14780	COG0831	urea catabolic process
CYL17_RS14780	COG0832	Belongs to the urease beta subunit family
CYL17_RS14800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CYL17_RS14800	COG3608	succinylglutamate desuccinylase aspartoacylase
CYL17_RS14810	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CYL17_RS14820	COG0375	protein maturation
CYL17_RS14850	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CYL17_RS14865	COG1595	DNA-templated transcription, initiation
CYL17_RS14870	COG2852	Protein conserved in bacteria
CYL17_RS14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYL17_RS14910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CYL17_RS14910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CYL17_RS14915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CYL17_RS14920	COG0297	glycogen (starch) synthase activity
CYL17_RS14925	COG0859	PFAM glycosyl transferase family 9
CYL17_RS14935	COG2192	nodulation
CYL17_RS14940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CYL17_RS14960	COG0121	glutamine amidotransferase
CYL17_RS14965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CYL17_RS14970	COG3572	ergothioneine biosynthetic process
CYL17_RS14985	COG0640	Transcriptional regulator
CYL17_RS14995	COG5297	Belongs to the glycosyl hydrolase family 6
CYL17_RS15015	COG0039	L-malate dehydrogenase activity
CYL17_RS15035	COG0215	cysteine-tRNA ligase activity
CYL17_RS15045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_RS15055	COG3629	intracellular signal transduction
CYL17_RS15055	COG3903	Transcriptional regulator
CYL17_RS15090	COG0726	polysaccharide deacetylase
CYL17_RS15090	COG1649	PFAM Uncharacterised BCR, COG1649
CYL17_RS15110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CYL17_RS15120	COG2197	response regulator
CYL17_RS15150	COG0477	Major facilitator Superfamily
CYL17_RS15165	COG0725	ABC transporter, periplasmic molybdate-binding protein
CYL17_RS15175	COG0783	Belongs to the Dps family
CYL17_RS15205	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS15210	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS15215	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS15235	COG0653	protein targeting
CYL17_RS15245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYL17_RS15270	COG0517	IMP dehydrogenase activity
CYL17_RS15270	COG0516	GMP reductase activity
CYL17_RS15275	COG2239	Acts as a magnesium transporter
CYL17_RS15285	COG1653	transport
CYL17_RS15295	COG0395	ABC-type sugar transport system, permease component
CYL17_RS15345	COG0210	DNA helicase
CYL17_RS15350	COG1111	helicase
CYL17_RS15350	COG1205	dead DEAH box helicase
CYL17_RS15355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYL17_RS15360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYL17_RS15365	COG2814	Major facilitator Superfamily
CYL17_RS15375	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CYL17_RS15440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CYL17_RS15445	COG4988	ABC transporter
CYL17_RS15450	COG1294	oxidase, subunit
CYL17_RS15455	COG1271	oxidase subunit
CYL17_RS15475	COG2130	NADP-dependent
CYL17_RS15480	COG1950	PFAM Membrane protein of
CYL17_RS15490	COG2807	transmembrane transport
CYL17_RS15505	COG1414	Transcriptional regulator
CYL17_RS15510	COG0667	Aldo Keto reductase
CYL17_RS15535	COG1217	gtp-binding protein TYPA
CYL17_RS15545	COG0433	COG0433 Predicted ATPase
CYL17_RS15550	COG0726	polysaccharide deacetylase
CYL17_RS15555	COG1476	TRANSCRIPTIONal
CYL17_RS15565	COG1595	DNA-templated transcription, initiation
CYL17_RS15580	COG1196	nuclear chromosome segregation
CYL17_RS15590	COG1254	Belongs to the acylphosphatase family
CYL17_RS15595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYL17_RS15600	COG0571	ribonuclease III activity
CYL17_RS15605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CYL17_RS15615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CYL17_RS15620	COG0742	ribosomal rna small subunit methyltransferase
CYL17_RS15630	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CYL17_RS15635	COG0351	phosphomethylpyrimidine kinase
CYL17_RS15660	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYL17_RS15665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CYL17_RS15675	COG1920	GTP binding
CYL17_RS15695	COG0776	regulation of translation
CYL17_RS15700	COG0066	3-isopropylmalate dehydratase activity
CYL17_RS15705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CYL17_RS15710	COG1414	Transcriptional regulator
CYL17_RS15735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYL17_RS15740	COG0179	Fumarylacetoacetate (FAA) hydrolase
CYL17_RS15755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYL17_RS15765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYL17_RS15770	COG0473	3-isopropylmalate dehydrogenase activity
CYL17_RS15775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CYL17_RS15785	COG2211	Major facilitator Superfamily
CYL17_RS15790	COG2340	Cysteine-rich secretory protein family
CYL17_RS15800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CYL17_RS15805	COG0440	acetolactate synthase activity
CYL17_RS15815	COG3300	MHYT domain
CYL17_RS15815	COG5001	Diguanylate cyclase
CYL17_RS15820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CYL17_RS15825	COG2133	pyrroloquinoline quinone binding
CYL17_RS15835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYL17_RS15840	COG0154	amidase activity
CYL17_RS15845	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYL17_RS15865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_RS15870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYL17_RS15880	COG3485	protocatechuate 3,4-dioxygenase
CYL17_RS15885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CYL17_RS15890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CYL17_RS15895	COG1414	Transcriptional regulator
CYL17_RS15900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CYL17_RS15915	COG0482	sulfurtransferase activity
CYL17_RS15930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CYL17_RS15945	COG0515	serine threonine protein kinase
CYL17_RS15945	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYL17_RS15960	COG2362	D-Aminopeptidase
CYL17_RS15975	COG1024	Enoyl-CoA hydratase
CYL17_RS15980	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS15990	COG0058	SHG alpha-glucan phosphorylase activity
CYL17_RS15995	COG0366	Alpha amylase catalytic
CYL17_RS16005	COG3281	Trehalose synthase
CYL17_RS16010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYL17_RS16020	COG0616	signal peptide processing
CYL17_RS16045	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS16065	COG1309	transcriptional regulator
CYL17_RS16075	COG0438	transferase activity, transferring glycosyl groups
CYL17_RS16080	COG2226	methyltransferase
CYL17_RS16115	COG0673	inositol 2-dehydrogenase activity
CYL17_RS16120	COG4213	ABC transporter substrate-binding protein
CYL17_RS16125	COG1172	Belongs to the binding-protein-dependent transport system permease family
CYL17_RS16130	COG1129	ABC transporter
CYL17_RS16135	COG1940	carbohydrate kinase activity
CYL17_RS16160	COG0567	Dehydrogenase, E1 component
CYL17_RS16160	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYL17_RS16175	COG0604	alcohol dehydrogenase
CYL17_RS16190	COG0488	(ABC) transporter
CYL17_RS16230	COG2172	sigma factor antagonist activity
CYL17_RS16245	COG1597	lipid kinase activity
CYL17_RS16260	COG2188	Transcriptional regulator
CYL17_RS16275	COG0515	serine threonine protein kinase
CYL17_RS16285	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CYL17_RS16310	COG1595	DNA-templated transcription, initiation
CYL17_RS16325	COG2135	peptidase activity
CYL17_RS16330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CYL17_RS16340	COG0483	inositol monophosphate 1-phosphatase activity
CYL17_RS16355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CYL17_RS16370	COG0581	inorganic phosphate transmembrane transporter activity
CYL17_RS16375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYL17_RS16390	COG0747	negative chemotaxis
CYL17_RS16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYL17_RS16435	COG0601	transmembrane transport
CYL17_RS16440	COG0747	negative chemotaxis
CYL17_RS16470	COG1615	UPF0182 protein
CYL17_RS16475	COG3480	Lon protease (S16) C-terminal proteolytic domain
CYL17_RS16515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYL17_RS16535	COG1946	Acyl-CoA thioesterase
CYL17_RS16565	COG4264	IucA IucC family
CYL17_RS16575	COG0019	diaminopimelate decarboxylase activity
CYL17_RS16585	COG0210	DNA helicase
CYL17_RS16590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CYL17_RS16615	COG1404	Belongs to the peptidase S8 family
CYL17_RS16660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CYL17_RS16665	COG1793	dna ligase
CYL17_RS16665	COG3285	dna ligase
CYL17_RS16690	COG0513	Belongs to the DEAD box helicase family
CYL17_RS16715	COG0494	nUDIX hydrolase
CYL17_RS16725	COG1266	CAAX protease self-immunity
CYL17_RS16730	COG2301	Belongs to the HpcH HpaI aldolase family
CYL17_RS16735	COG1268	BioY protein
CYL17_RS16755	COG2239	Acts as a magnesium transporter
CYL17_RS16770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYL17_RS16790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYL17_RS16800	COG1024	Enoyl-CoA hydratase
CYL17_RS16805	COG0519	Catalyzes the synthesis of GMP from XMP
CYL17_RS16820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CYL17_RS16830	COG1611	Belongs to the LOG family
CYL17_RS16860	COG4106	trans-aconitate 2-methyltransferase activity
CYL17_RS16870	COG0210	DNA helicase
CYL17_RS16880	COG0215	cysteine-tRNA ligase activity
CYL17_RS16890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_RS16905	COG0542	response to heat
CYL17_RS16920	COG1053	succinate dehydrogenase
CYL17_RS16935	COG0494	nUDIX hydrolase
CYL17_RS16940	COG0791	NLP P60 protein
CYL17_RS16940	COG1388	LysM domain
CYL17_RS16975	COG0012	GTP binding
CYL17_RS16980	COG1322	Protein conserved in bacteria
CYL17_RS16990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CYL17_RS17000	COG1570	exodeoxyribonuclease VII activity
CYL17_RS17005	COG0367	asparagine synthase
CYL17_RS17010	COG1722	exodeoxyribonuclease VII activity
CYL17_RS17040	COG3962	Belongs to the TPP enzyme family
CYL17_RS17045	COG3718	enzyme involved in inositol metabolism
CYL17_RS17055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYL17_RS17065	COG0673	inositol 2-dehydrogenase activity
CYL17_RS17080	COG0515	serine threonine protein kinase
CYL17_RS17085	COG2815	serine threonine protein kinase
CYL17_RS17085	COG0515	serine threonine protein kinase
CYL17_RS17090	COG0114	fumarate hydratase activity
CYL17_RS17100	COG1215	transferase activity, transferring glycosyl groups
CYL17_RS17110	COG0745	RESPONSE REGULATOR receiver
CYL17_RS17115	COG2205	protein histidine kinase activity
CYL17_RS17125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CYL17_RS17130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYL17_RS17135	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CYL17_RS17145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CYL17_RS17155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CYL17_RS17195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CYL17_RS17205	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CYL17_RS17215	COG0180	Tryptophanyl-tRNA synthetase
CYL17_RS17220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CYL17_RS17230	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CYL17_RS17255	COG2755	lipolytic protein G-D-S-L family
CYL17_RS17265	COG0183	Belongs to the thiolase family
CYL17_RS17285	COG2205	protein histidine kinase activity
CYL17_RS17290	COG0477	Major facilitator Superfamily
CYL17_RS17325	COG0148	phosphopyruvate hydratase activity
CYL17_RS17350	COG0529	Catalyzes the synthesis of activated sulfate
CYL17_RS17370	COG0515	serine threonine protein kinase
CYL17_RS17370	COG2815	serine threonine protein kinase
CYL17_RS17410	COG1218	3'(2'),5'-bisphosphate nucleotidase
CYL17_RS17415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYL17_RS17420	COG0193	aminoacyl-tRNA hydrolase activity
CYL17_RS17425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CYL17_RS17430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYL17_RS17435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYL17_RS17450	COG1309	transcriptional regulator
CYL17_RS17455	COG4106	trans-aconitate 2-methyltransferase activity
CYL17_RS17495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CYL17_RS17500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYL17_RS17505	COG0084	hydrolase, TatD family'
CYL17_RS17515	COG2132	Multicopper oxidase
CYL17_RS17525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYL17_RS17585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CYL17_RS17590	COG0521	Mo-molybdopterin cofactor biosynthetic process
CYL17_RS17595	COG0315	cyclic pyranopterin monophosphate synthase activity
CYL17_RS17605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CYL17_RS17610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CYL17_RS17615	COG3263	regulation of cellular component size
CYL17_RS17625	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CYL17_RS17660	COG1252	NADH dehydrogenase
CYL17_RS17665	COG1595	DNA-templated transcription, initiation
CYL17_RS17670	COG1309	transcriptional regulator
CYL17_RS17675	COG1131	(ABC) transporter
CYL17_RS17680	COG3559	Exporter of polyketide antibiotics
CYL17_RS17690	COG0477	Major facilitator Superfamily
CYL17_RS17695	COG0477	Major facilitator Superfamily
CYL17_RS17700	COG2030	dehydratase
CYL17_RS17705	COG1960	acyl-CoA dehydrogenase activity
CYL17_RS17710	COG1024	Enoyl-CoA hydratase
CYL17_RS17715	COG0154	amidase activity
CYL17_RS17725	COG2267	carboxylic ester hydrolase activity
CYL17_RS17730	COG0318	PFAM AMP-dependent synthetase and ligase
CYL17_RS17760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYL17_RS17765	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CYL17_RS17770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CYL17_RS17775	COG0375	protein maturation
CYL17_RS17800	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CYL17_RS17845	COG0309	Hydrogenase expression formation protein (HypE)
CYL17_RS17850	COG0298	carbon dioxide binding
CYL17_RS17855	COG0409	Hydrogenase expression formation protein
CYL17_RS17870	COG1063	alcohol dehydrogenase
CYL17_RS17885	COG0247	lactate metabolic process
CYL17_RS17890	COG1139	Iron-sulfur cluster binding protein
CYL17_RS17895	COG1556	Lactate utilization protein
CYL17_RS17915	COG0395	ABC-type sugar transport system, permease component
CYL17_RS17920	COG1175	transmembrane transport
CYL17_RS17970	COG0477	Major facilitator Superfamily
CYL17_RS17975	COG0662	Cupin 2, conserved barrel domain protein
CYL17_RS17990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYL17_RS18000	COG0745	RESPONSE REGULATOR receiver
CYL17_RS18010	COG0577	efflux transmembrane transporter activity
CYL17_RS18010	COG1136	(ABC) transporter
CYL17_RS18015	COG1136	(ABC) transporter
CYL17_RS18030	COG2205	protein histidine kinase activity
CYL17_RS18035	COG0745	RESPONSE REGULATOR receiver
CYL17_RS18040	COG0579	oxidoreductase
CYL17_RS18060	COG1695	Transcriptional regulator
CYL17_RS18075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYL17_RS18085	COG0667	Aldo Keto reductase
CYL17_RS18105	COG2252	PERMEase
CYL17_RS18125	COG1278	Cold shock
CYL17_RS18140	COG3973	AAA domain
CYL17_RS18145	COG0459	protein refolding
CYL17_RS18155	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYL17_RS18170	COG4974	Belongs to the 'phage' integrase family
CYL17_RS18180	COG0717	Belongs to the dCTP deaminase family
CYL17_RS18330	COG2226	methyltransferase
CYL17_RS18380	COG1192	Involved in chromosome partitioning
CYL17_RS18515	COG0592	DNA-directed DNA polymerase activity
CYL17_RS18550	COG1609	Transcriptional regulator
CYL17_RS18715	COG3629	intracellular signal transduction
CYL17_RS18715	COG3903	Transcriptional regulator
CYL17_RS18760	COG0717	Belongs to the dCTP deaminase family