locus-tag	class	description
OCC_RS00005	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OCC_RS00050	COG1518	maintenance of DNA repeat elements
OCC_RS00060	COG1203	CRISPR-associated helicase, Cas3
OCC_RS00085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCC_RS00105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCC_RS00115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OCC_RS00130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OCC_RS00135	COG0492	ferredoxin-NADP+ reductase activity
OCC_RS00155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OCC_RS00165	COG1628	Protein of unknown function DUF99
OCC_RS00175	COG1254	Belongs to the acylphosphatase family
OCC_RS00205	COG0037	tRNA processing
OCC_RS00225	COG0095	Lipoate-protein ligase
OCC_RS00230	COG0681	Belongs to the peptidase S26 family
OCC_RS00250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCC_RS00255	COG0482	sulfurtransferase activity
OCC_RS00350	COG1078	dGTPase activity
OCC_RS00365	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCC_RS00400	COG1199	ATP-dependent helicase activity
OCC_RS00415	COG1489	DNA binding
OCC_RS00425	COG4974	Belongs to the 'phage' integrase family
OCC_RS00435	COG3473	Maleate cis-trans isomerase
OCC_RS00440	COG1355	regulation of microtubule-based process
OCC_RS00450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCC_RS00465	COG2361	Protein of unknown function DUF86
OCC_RS00505	COG1304	FMN binding
OCC_RS00510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OCC_RS00515	COG0142	geranyltranstransferase activity
OCC_RS00540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OCC_RS00575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OCC_RS00605	COG0641	radical SAM
OCC_RS00675	COG1121	(ABC) transporter
OCC_RS00680	COG1131	(ABC) transporter
OCC_RS00740	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OCC_RS00745	COG1122	ATPase activity
OCC_RS00750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OCC_RS00750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OCC_RS00755	COG1268	BioY protein
OCC_RS00780	COG1694	Mazg nucleotide pyrophosphohydrolase
OCC_RS00785	COG1522	sequence-specific DNA binding
OCC_RS00790	COG1836	PFAM Integral membrane protein DUF92
OCC_RS00815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OCC_RS00825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCC_RS00830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCC_RS00860	COG0501	Belongs to the peptidase M48B family
OCC_RS00865	COG2131	deaminase
OCC_RS00875	COG0546	phosphoglycolate phosphatase activity
OCC_RS00880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCC_RS00915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OCC_RS00920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCC_RS00930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCC_RS00990	COG1378	Sugar-specific transcriptional regulator TrmB
OCC_RS00995	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OCC_RS01030	COG0489	protein tyrosine kinase activity
OCC_RS01035	COG0489	protein tyrosine kinase activity
OCC_RS01045	COG1342	Belongs to the UPF0251 family
OCC_RS01050	COG0513	Belongs to the DEAD box helicase family
OCC_RS01065	COG2362	D-Aminopeptidase
OCC_RS01070	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OCC_RS01095	COG2894	cell division
OCC_RS01100	COG0330	HflC and HflK could
OCC_RS01115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OCC_RS01130	COG1111	helicase
OCC_RS01130	COG1205	dead DEAH box helicase
OCC_RS01140	COG1121	(ABC) transporter
OCC_RS01150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCC_RS01170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OCC_RS01225	COG2022	thiamine diphosphate biosynthetic process
OCC_RS01225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCC_RS01250	COG0733	neurotransmitter:sodium symporter activity
OCC_RS01265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCC_RS01275	COG2723	6-phospho-beta-galactosidase activity
OCC_RS01280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCC_RS01295	COG1011	Hydrolase
OCC_RS01305	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OCC_RS01325	COG0556	nucleotide-excision repair
OCC_RS01330	COG0101	tRNA pseudouridine synthase activity
OCC_RS01350	COG1063	alcohol dehydrogenase
OCC_RS01360	COG2894	cell division
OCC_RS01380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OCC_RS01385	COG0252	asparaginase activity
OCC_RS01470	COG2226	methyltransferase
OCC_RS01490	COG4221	oxidoreductase activity
OCC_RS01495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCC_RS01500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OCC_RS01515	COG2723	6-phospho-beta-galactosidase activity
OCC_RS01520	COG1085	galactose-1-phosphate uridylyltransferase
OCC_RS01540	COG1185	polyribonucleotide nucleotidyltransferase activity
OCC_RS01570	COG0656	L-ascorbic acid biosynthetic process
OCC_RS01585	COG0243	molybdopterin cofactor binding
OCC_RS01620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCC_RS01625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OCC_RS01655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OCC_RS01710	COG0598	Magnesium transport protein CorA
OCC_RS01730	COG0312	modulator of DNA gyrase
OCC_RS01735	COG0312	modulator of DNA gyrase
OCC_RS01750	COG0105	UTP biosynthetic process
OCC_RS01755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCC_RS01780	COG1110	DNA topoisomerase II activity
OCC_RS01785	COG0045	succinate-CoA ligase (ADP-forming) activity
OCC_RS01785	COG1042	CoA-binding domain protein
OCC_RS01785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCC_RS01830	COG0693	protein deglycase activity
OCC_RS01840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCC_RS01845	COG0071	Belongs to the small heat shock protein (HSP20) family
OCC_RS01860	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
OCC_RS01865	COG0534	Mate efflux family protein
OCC_RS01885	COG0012	GTP binding
OCC_RS01895	COG1522	sequence-specific DNA binding
OCC_RS01900	COG0163	prenyltransferase activity
OCC_RS01910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCC_RS01920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OCC_RS01920	COG1918	ferrous iron import across plasma membrane
OCC_RS01935	COG0628	permease
OCC_RS01945	COG0616	signal peptide processing
OCC_RS01970	COG1185	polyribonucleotide nucleotidyltransferase activity
OCC_RS01985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OCC_RS01995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OCC_RS02035	COG1993	acr, cog1993
OCC_RS02040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCC_RS02080	COG2414	aldehyde ferredoxin oxidoreductase
OCC_RS02095	COG0469	pyruvate kinase activity
OCC_RS02100	COG1058	Belongs to the CinA family
OCC_RS02100	COG1546	Belongs to the CinA family
OCC_RS02125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OCC_RS02130	COG0352	thiamine-phosphate diphosphorylase activity
OCC_RS02140	COG0351	phosphomethylpyrimidine kinase
OCC_RS02170	COG1449	Belongs to the glycosyl hydrolase 57 family
OCC_RS02175	COG0037	tRNA processing
OCC_RS02180	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OCC_RS02195	COG0475	glutathione-regulated potassium exporter activity
OCC_RS02210	COG1522	sequence-specific DNA binding
OCC_RS02225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OCC_RS02230	COG0540	Belongs to the ATCase OTCase family
OCC_RS02235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OCC_RS02240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCC_RS02245	COG0543	2 iron, 2 sulfur cluster binding
OCC_RS02250	COG0167	dihydroorotate dehydrogenase activity
OCC_RS02265	COG0585	pseudouridine synthase activity
OCC_RS02280	COG0017	Asparaginyl-tRNA synthetase
OCC_RS02290	COG1418	mRNA catabolic process
OCC_RS02315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OCC_RS02370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCC_RS02390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OCC_RS02400	COG1121	(ABC) transporter
OCC_RS02405	COG2095	MarC family integral membrane protein
OCC_RS02410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCC_RS02430	COG0006	proline dipeptidase activity
OCC_RS02485	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
OCC_RS02490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCC_RS02520	COG0049	tRNA binding
OCC_RS02540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCC_RS02545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCC_RS02550	COG0085	RNA polymerase activity
OCC_RS02595	COG0717	Belongs to the dCTP deaminase family
OCC_RS02610	COG0081	regulation of translation
OCC_RS02615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OCC_RS02630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCC_RS02665	COG1458	PINc domain ribonuclease
OCC_RS02685	COG0434	BtpA family
OCC_RS02890	COG4143	(ABC) transporter
OCC_RS02895	COG3842	ATPase activity
OCC_RS02920	COG3842	ATPase activity
OCC_RS02930	COG0438	transferase activity, transferring glycosyl groups
OCC_RS02945	COG1653	transport
OCC_RS02960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OCC_RS02975	COG0301	tRNA thio-modification
OCC_RS02985	COG0052	Belongs to the universal ribosomal protein uS2 family
OCC_RS02990	COG0148	phosphopyruvate hydratase activity
OCC_RS03010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCC_RS03015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OCC_RS03035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OCC_RS03040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OCC_RS03045	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCC_RS03055	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCC_RS03075	COG1102	Psort location Cytoplasmic, score
OCC_RS03100	COG0200	Binds to the 23S rRNA
OCC_RS03105	COG1841	ribosomal large subunit assembly
OCC_RS03110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OCC_RS03115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OCC_RS03130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCC_RS03135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCC_RS03145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OCC_RS03155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCC_RS03160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OCC_RS03165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCC_RS03180	COG0255	Belongs to the universal ribosomal protein uL29 family
OCC_RS03185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCC_RS03190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OCC_RS03195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCC_RS03200	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCC_RS03205	COG0089	rRNA binding
OCC_RS03210	COG0088	Forms part of the polypeptide exit tunnel
OCC_RS03215	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCC_RS03235	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
OCC_RS03260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OCC_RS03265	COG0651	ATP synthesis coupled electron transport
OCC_RS03270	COG0650	Formate hydrogenlyase subunit 4
OCC_RS03275	COG3261	NADH dehydrogenase
OCC_RS03275	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
OCC_RS03280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS03285	COG3260	NADH ubiquinone oxidoreductase 20
OCC_RS03295	COG2212	antiporter activity
OCC_RS03315	COG1006	Multisubunit Na H antiporter MnhC subunit
OCC_RS03325	COG0651	ATP synthesis coupled electron transport
OCC_RS03335	COG0493	'glutamate synthase
OCC_RS03335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCC_RS03340	COG0437	4 iron, 4 sulfur cluster binding
OCC_RS03345	COG0477	Major facilitator Superfamily
OCC_RS03365	COG2814	Major facilitator Superfamily
OCC_RS03370	COG1446	asparaginase
OCC_RS03380	COG0534	Mate efflux family protein
OCC_RS03390	COG0534	Mate efflux family protein
OCC_RS03395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCC_RS03395	COG0574	Belongs to the PEP-utilizing enzyme family
OCC_RS03425	COG1473	amidohydrolase
OCC_RS03450	COG0840	transmembrane signaling receptor activity
OCC_RS03465	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCC_RS03475	COG0495	leucyl-tRNA aminoacylation
OCC_RS03490	COG0509	glycine decarboxylation via glycine cleavage system
OCC_RS03495	COG1793	dna ligase
OCC_RS03495	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OCC_RS03510	COG3769	mannosylglycerate metabolic process
OCC_RS03515	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OCC_RS03515	COG0662	Cupin 2, conserved barrel domain protein
OCC_RS03525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCC_RS03535	COG0010	Belongs to the arginase family
OCC_RS03550	COG1748	Saccharopine dehydrogenase
OCC_RS03565	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OCC_RS03565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCC_RS03595	COG1966	Carbon starvation protein
OCC_RS03605	COG1830	Aldolase
OCC_RS03610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OCC_RS03610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OCC_RS03625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCC_RS03650	COG1178	ABC-type Fe3 transport system permease component
OCC_RS03655	COG3842	ATPase activity
OCC_RS03675	COG1715	Restriction endonuclease
OCC_RS03680	COG0126	phosphoglycerate kinase activity
OCC_RS03705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCC_RS03725	COG1042	CoA-binding domain protein
OCC_RS03725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCC_RS03725	COG0045	succinate-CoA ligase (ADP-forming) activity
OCC_RS03765	COG4555	ABC transporter
OCC_RS03770	COG2814	Major facilitator Superfamily
OCC_RS03780	COG1234	tRNA 3'-trailer cleavage
OCC_RS03785	COG0432	Pfam Uncharacterised protein family UPF0047
OCC_RS03815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCC_RS03840	COG0237	dephospho-CoA kinase activity
OCC_RS03875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCC_RS03885	COG1744	ABC transporter substrate-binding protein PnrA-like
OCC_RS03890	COG3845	ABC transporter
OCC_RS03895	COG4603	Belongs to the binding-protein-dependent transport system permease family
OCC_RS03900	COG1079	Belongs to the binding-protein-dependent transport system permease family
OCC_RS03905	COG0803	Belongs to the bacterial solute-binding protein 9 family
OCC_RS03960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCC_RS03980	COG0215	cysteine-tRNA ligase activity
OCC_RS03985	COG1047	Peptidyl-prolyl cis-trans
OCC_RS04005	COG1136	(ABC) transporter
OCC_RS04010	COG1505	serine-type exopeptidase activity
OCC_RS04020	COG1201	RNA secondary structure unwinding
OCC_RS04040	COG3842	ATPase activity
OCC_RS04050	COG1106	Psort location Cytoplasmic, score
OCC_RS04055	COG4149	molybdate abc transporter
OCC_RS04060	COG0725	ABC transporter, periplasmic molybdate-binding protein
OCC_RS04065	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
OCC_RS04075	COG2239	Acts as a magnesium transporter
OCC_RS04080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OCC_RS04105	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
OCC_RS04110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OCC_RS04120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OCC_RS04165	COG1363	Peptidase, m42
OCC_RS04170	COG0730	response to heat
OCC_RS04175	COG0730	response to heat
OCC_RS04210	COG1141	Ferredoxin
OCC_RS04215	COG1141	Ferredoxin
OCC_RS04220	COG2151	metal-sulfur cluster biosynthetic enzyme
OCC_RS04235	COG0281	malic enzyme
OCC_RS04255	COG2226	methyltransferase
OCC_RS04295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCC_RS04310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OCC_RS04320	COG1530	ribonuclease E activity
OCC_RS04330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCC_RS04345	COG2255	four-way junction helicase activity
OCC_RS04355	COG0156	8-amino-7-oxononanoate synthase activity
OCC_RS04370	COG0456	acetyltransferase
OCC_RS04375	COG0366	Alpha amylase catalytic
OCC_RS04380	COG0433	COG0433 Predicted ATPase
OCC_RS04400	COG0343	queuine tRNA-ribosyltransferase activity
OCC_RS04405	COG1215	transferase activity, transferring glycosyl groups
OCC_RS04415	COG1067	ATP-dependent peptidase activity
OCC_RS04415	COG0470	DNA polymerase III
OCC_RS04435	COG1346	cytolysis
OCC_RS04470	COG1695	Transcriptional regulator
OCC_RS04490	COG2264	protein methyltransferase activity
OCC_RS04500	COG0668	transmembrane transport
OCC_RS04525	COG3383	formate dehydrogenase (NAD+) activity
OCC_RS04530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCC_RS04535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCC_RS04545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCC_RS04550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OCC_RS04555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OCC_RS04560	COG0151	Belongs to the GarS family
OCC_RS04570	COG0535	radical SAM domain protein
OCC_RS04575	COG1132	(ABC) transporter
OCC_RS04600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCC_RS04605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCC_RS04610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCC_RS04615	COG0157	Belongs to the NadC ModD family
OCC_RS04620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCC_RS04620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCC_RS04625	COG0307	riboflavin synthase, alpha
OCC_RS04630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCC_RS04630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCC_RS04635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OCC_RS04650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCC_RS04655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OCC_RS04660	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
OCC_RS04670	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OCC_RS04690	COG0517	IMP dehydrogenase activity
OCC_RS04690	COG0516	GMP reductase activity
OCC_RS04695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCC_RS04695	COG0519	Catalyzes the synthesis of GMP from XMP
OCC_RS04700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCC_RS04700	COG0519	Catalyzes the synthesis of GMP from XMP
OCC_RS04765	COG2890	protein-(glutamine-N5) methyltransferase activity
OCC_RS04790	COG0539	negative regulation of cytoplasmic translation
OCC_RS04815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OCC_RS04820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCC_RS04830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OCC_RS04835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OCC_RS04860	COG0297	glycogen (starch) synthase activity
OCC_RS04860	COG0438	transferase activity, transferring glycosyl groups
OCC_RS04875	COG0438	transferase activity, transferring glycosyl groups
OCC_RS04920	COG2442	InterPro IPR007367
OCC_RS04965	COG0463	Glycosyl transferase, family 2
OCC_RS05005	COG0714	Associated with various cellular activities
OCC_RS05065	COG0463	Glycosyl transferase, family 2
OCC_RS05215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCC_RS05215	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OCC_RS05220	COG0402	S-adenosylhomocysteine deaminase activity
OCC_RS05250	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
OCC_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
OCC_RS05310	COG0475	glutathione-regulated potassium exporter activity
OCC_RS05315	COG1522	sequence-specific DNA binding
OCC_RS05350	COG0647	UMP catabolic process
OCC_RS05365	COG0438	transferase activity, transferring glycosyl groups
OCC_RS05405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OCC_RS05405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OCC_RS05420	COG0640	Transcriptional regulator
OCC_RS05440	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCC_RS05455	COG0704	Plays a role in the regulation of phosphate uptake
OCC_RS05460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCC_RS05470	COG0573	inorganic phosphate transmembrane transporter activity
OCC_RS05480	COG1785	Belongs to the alkaline phosphatase family
OCC_RS05490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCC_RS05490	COG0116	Belongs to the methyltransferase superfamily
OCC_RS05500	COG4174	ABC transporter (Permease)
OCC_RS05545	COG1047	Peptidyl-prolyl cis-trans
OCC_RS05570	COG0714	Associated with various cellular activities
OCC_RS05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCC_RS05630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OCC_RS05645	COG2198	Histidine kinase
OCC_RS05645	COG0643	Histidine kinase
OCC_RS05650	COG2201	protein-glutamate methylesterase activity
OCC_RS05655	COG2201	protein-glutamate methylesterase activity
OCC_RS05665	COG0835	chemotaxis
OCC_RS05835	COG2002	toxin-antitoxin pair type II binding
OCC_RS05880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCC_RS05885	COG0018	arginyl-trna synthetase
OCC_RS05910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OCC_RS05930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCC_RS05940	COG1863	multisubunit Na H antiporter MnhE subunit
OCC_RS05945	COG2212	antiporter activity
OCC_RS05950	COG1320	monovalent cation:proton antiporter activity
OCC_RS05960	COG2111	Na H antiporter
OCC_RS05960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OCC_RS05970	COG0651	ATP synthesis coupled electron transport
OCC_RS05975	COG0651	ATP synthesis coupled electron transport
OCC_RS05980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OCC_RS05985	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS05990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS05995	COG0649	NAD binding
OCC_RS06010	COG0450	alkyl hydroperoxide reductase
OCC_RS06020	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCC_RS06025	COG0450	alkyl hydroperoxide reductase
OCC_RS06055	COG1592	Rubrerythrin
OCC_RS06060	COG1773	rubredoxin
OCC_RS06065	COG2033	superoxide reductase activity
OCC_RS06080	COG1850	ribulose-bisphosphate carboxylase activity
OCC_RS06090	COG1732	Glycine betaine
OCC_RS06095	COG1125	glycine betaine transport
OCC_RS06095	COG0517	IMP dehydrogenase activity
OCC_RS06115	COG0668	transmembrane transport
OCC_RS06140	COG0735	belongs to the Fur family
OCC_RS06150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCC_RS06200	COG1297	OPT oligopeptide transporter protein
OCC_RS06210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCC_RS06220	COG3842	ATPase activity
OCC_RS06230	COG3833	ABC-type maltose transport systems, permease component
OCC_RS06240	COG2182	Extracellular solute-binding protein
OCC_RS06250	COG1378	Sugar-specific transcriptional regulator TrmB
OCC_RS06255	COG0297	glycogen (starch) synthase activity
OCC_RS06265	COG0442	prolyl-tRNA aminoacylation
OCC_RS06285	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS06300	COG3842	ATPase activity
OCC_RS06305	COG0395	ABC-type sugar transport system, permease component
OCC_RS06310	COG1175	transmembrane transport
OCC_RS06330	COG1394	ATPase activity, coupled to movement of substances
OCC_RS06340	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
OCC_RS06355	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
OCC_RS06365	COG1269	ATP hydrolysis coupled proton transport
OCC_RS06375	COG0569	domain protein
OCC_RS06380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCC_RS06390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OCC_RS06400	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OCC_RS06450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OCC_RS06470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCC_RS06570	COG3842	ATPase activity
OCC_RS06590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCC_RS06635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCC_RS06640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OCC_RS06650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCC_RS06650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCC_RS06680	COG1032	radical SAM domain protein
OCC_RS06690	COG1510	regulation of RNA biosynthetic process
OCC_RS06705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCC_RS06710	COG0314	molybdopterin synthase activity
OCC_RS06725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCC_RS06750	COG1720	tRNA m6t6A37 methyltransferase activity
OCC_RS06755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCC_RS06760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCC_RS06765	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCC_RS06775	COG0557	exoribonuclease II activity
OCC_RS06790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCC_RS06810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OCC_RS06815	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OCC_RS06850	COG0174	glutamine synthetase
OCC_RS06860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OCC_RS06870	COG4608	Belongs to the ABC transporter superfamily
OCC_RS06875	COG0444	Belongs to the ABC transporter superfamily
OCC_RS06880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCC_RS06885	COG0601	transmembrane transport
OCC_RS06925	COG1131	(ABC) transporter
OCC_RS06955	COG1151	hydroxylamine reductase activity
OCC_RS07065	COG0426	domain, Protein
OCC_RS07080	COG0006	proline dipeptidase activity
OCC_RS07125	COG0534	Mate efflux family protein
OCC_RS07140	COG0778	Nitroreductase
OCC_RS07145	COG2084	Dehydrogenase
OCC_RS07150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCC_RS07155	COG0301	tRNA thio-modification
OCC_RS07165	COG1528	Iron-storage protein
OCC_RS07190	COG0396	ATPase activity
OCC_RS07200	COG0719	Fe-S assembly protein
OCC_RS07215	COG0134	indole-3-glycerol-phosphate synthase activity
OCC_RS07225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCC_RS07230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCC_RS07230	COG0512	Glutamine amidotransferase of anthranilate synthase
OCC_RS07235	COG0135	phosphoribosylanthranilate isomerase activity
OCC_RS07240	COG0133	tryptophan synthase activity
OCC_RS07245	COG0159	tryptophan synthase activity
OCC_RS07255	COG0436	Aminotransferase
OCC_RS07260	COG0287	Prephenate dehydrogenase
OCC_RS07260	COG1605	Chorismate mutase
OCC_RS07270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCC_RS07280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCC_RS07290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCC_RS07295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OCC_RS07300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCC_RS07315	COG0450	alkyl hydroperoxide reductase
OCC_RS07345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCC_RS07360	COG0697	spore germination
OCC_RS07380	COG0640	Transcriptional regulator
OCC_RS07385	COG2217	Heavy metal translocating P-type atpase
OCC_RS07410	COG0626	cystathionine gamma-synthase activity
OCC_RS07465	COG0798	PFAM Bile acid sodium symporter
OCC_RS07470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OCC_RS07485	COG0798	PFAM Bile acid sodium symporter
OCC_RS07495	COG1230	cation diffusion facilitator family transporter
OCC_RS07520	COG1137	ATPase activity
OCC_RS07525	COG0719	Fe-S assembly protein
OCC_RS07540	COG1980	fructose-bisphosphate aldolase activity
OCC_RS07560	COG3842	ATPase activity
OCC_RS07565	COG3833	ABC-type maltose transport systems, permease component
OCC_RS07590	COG0463	Glycosyl transferase, family 2
OCC_RS07625	COG2814	Major facilitator Superfamily
OCC_RS07670	COG0252	asparaginase activity
OCC_RS07680	COG1695	Transcriptional regulator
OCC_RS07690	COG2050	protein possibly involved in aromatic compounds catabolism
OCC_RS07690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OCC_RS07700	COG1335	isochorismatase
OCC_RS07705	COG0628	permease
OCC_RS07730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCC_RS07730	COG0519	Catalyzes the synthesis of GMP from XMP
OCC_RS07740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCC_RS07770	COG1160	GTP binding
OCC_RS07815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCC_RS07850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OCC_RS07855	COG0022	dehydrogenase e1 component
OCC_RS07865	COG0095	Lipoate-protein ligase
OCC_RS07870	COG3199	ATP-NAD kinase
OCC_RS07880	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCC_RS07890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OCC_RS07895	COG0022	dehydrogenase e1 component
OCC_RS07920	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OCC_RS07935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCC_RS07965	COG2379	hydroxypyruvate reductase
OCC_RS07970	COG0527	aspartate kinase activity
OCC_RS07975	COG0083	homoserine kinase activity
OCC_RS07980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCC_RS07990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCC_RS07995	COG1435	thymidine kinase activity
OCC_RS08015	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
OCC_RS08025	COG0309	Hydrogenase expression formation protein (HypE)
OCC_RS08035	COG1522	sequence-specific DNA binding
OCC_RS08040	COG0436	Aminotransferase
OCC_RS08060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCC_RS08065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCC_RS08070	COG1979	alcohol dehydrogenase
OCC_RS08085	COG0024	Methionine aminopeptidase
OCC_RS08090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCC_RS08095	COG1122	ATPase activity
OCC_RS08135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCC_RS08140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCC_RS08145	COG0017	Asparaginyl-tRNA synthetase
OCC_RS08155	COG0778	Nitroreductase
OCC_RS08190	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
OCC_RS08240	COG0430	RNA-3'-phosphate cyclase activity
OCC_RS08260	COG0305	Participates in initiation and elongation during chromosome replication
OCC_RS08260	COG1372	Participates in initiation and elongation during chromosome replication
OCC_RS08270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OCC_RS08285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OCC_RS08295	COG1739	Uncharacterized protein family UPF0029
OCC_RS08325	COG0515	serine threonine protein kinase
OCC_RS08335	COG1193	negative regulation of DNA recombination
OCC_RS08340	COG0315	cyclic pyranopterin monophosphate synthase activity
OCC_RS08345	COG0393	Putative heavy-metal-binding
OCC_RS08355	COG1131	(ABC) transporter
OCC_RS08380	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OCC_RS08380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCC_RS08415	COG0051	transcription antitermination factor activity, RNA binding
OCC_RS08420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCC_RS08455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCC_RS08465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OCC_RS08480	COG1288	antiporter activity
OCC_RS08505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OCC_RS08510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCC_RS08515	COG1492	cobalamin metabolic process
OCC_RS08535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OCC_RS08555	COG1573	uracil-dna glycosylase
OCC_RS08560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OCC_RS08565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCC_RS08575	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
OCC_RS08595	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
OCC_RS08600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCC_RS08645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCC_RS08690	COG0517	IMP dehydrogenase activity
OCC_RS08690	COG0516	GMP reductase activity
OCC_RS08705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCC_RS08725	COG0674	pyruvate-flavodoxin oxidoreductase activity
OCC_RS08725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OCC_RS08730	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCC_RS08740	COG0674	pyruvate-flavodoxin oxidoreductase activity
OCC_RS08740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OCC_RS08745	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCC_RS08755	COG0493	'glutamate synthase
OCC_RS08760	COG0543	2 iron, 2 sulfur cluster binding
OCC_RS08770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCC_RS08780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCC_RS08785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCC_RS08800	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OCC_RS08810	COG1201	RNA secondary structure unwinding
OCC_RS08815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCC_RS08825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCC_RS08830	COG0601	transmembrane transport
OCC_RS08840	COG4166	transmembrane transport
OCC_RS08875	COG1473	amidohydrolase
OCC_RS08885	COG1122	ATPase activity
OCC_RS08890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OCC_RS08900	COG0778	Nitroreductase
OCC_RS08910	COG1522	sequence-specific DNA binding
OCC_RS08920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCC_RS08925	COG1473	amidohydrolase
OCC_RS08930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OCC_RS08940	COG1522	sequence-specific DNA binding
OCC_RS08945	COG0747	negative chemotaxis
OCC_RS08950	COG0601	transmembrane transport
OCC_RS08960	COG0444	Belongs to the ABC transporter superfamily
OCC_RS08965	COG4608	Belongs to the ABC transporter superfamily
OCC_RS08990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCC_RS09005	COG0084	hydrolase, TatD family'
OCC_RS09020	COG1131	(ABC) transporter
OCC_RS09050	COG0298	carbon dioxide binding
OCC_RS09055	COG0409	Hydrogenase expression formation protein
OCC_RS09090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCC_RS09105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCC_RS09110	COG0477	Major facilitator Superfamily
OCC_RS09135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OCC_RS09165	COG0009	L-threonylcarbamoyladenylate synthase
OCC_RS09170	COG0297	glycogen (starch) synthase activity
OCC_RS09180	COG0367	asparagine synthase
OCC_RS09190	COG2894	cell division
OCC_RS09200	COG0424	maF-like protein
OCC_RS09215	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OCC_RS09215	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OCC_RS09225	COG0346	lactoylglutathione lyase activity
OCC_RS09245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OCC_RS09250	COG0303	'Molybdopterin
OCC_RS09265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCC_RS09285	COG1476	TRANSCRIPTIONal
OCC_RS09295	COG1131	(ABC) transporter
OCC_RS09320	COG0674	pyruvate-flavodoxin oxidoreductase activity
OCC_RS09325	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCC_RS09335	COG0674	pyruvate-flavodoxin oxidoreductase activity
OCC_RS09340	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCC_RS09345	COG0489	protein tyrosine kinase activity
OCC_RS09370	COG1131	(ABC) transporter
OCC_RS09385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCC_RS09390	COG0312	modulator of DNA gyrase
OCC_RS09395	COG0312	modulator of DNA gyrase
OCC_RS09410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCC_RS09440	COG0504	CTP synthase activity
OCC_RS09585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCC_RS09605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OCC_RS09620	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCC_RS09625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCC_RS09675	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OCC_RS09675	COG0359	binds to the 23S rRNA
OCC_RS09690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCC_RS09690	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCC_RS09730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OCC_RS09730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OCC_RS09735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCC_RS09750	COG0436	Aminotransferase
OCC_RS09755	COG2119	membrane
OCC_RS09775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCC_RS09785	COG0733	neurotransmitter:sodium symporter activity
OCC_RS09800	COG0528	UMP kinase activity
OCC_RS09805	COG0058	SHG alpha-glucan phosphorylase activity
OCC_RS09810	COG1122	ATPase activity
OCC_RS09825	COG0310	cobalt ion transport
OCC_RS09835	COG0517	IMP dehydrogenase activity
OCC_RS09835	COG0516	GMP reductase activity
OCC_RS09845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OCC_RS09850	COG1968	undecaprenyl-diphosphatase activity
OCC_RS09860	COG1863	multisubunit Na H antiporter MnhE subunit
OCC_RS09865	COG2212	antiporter activity
OCC_RS09870	COG1320	monovalent cation:proton antiporter activity
OCC_RS09890	COG1006	Multisubunit Na H antiporter MnhC subunit
OCC_RS09895	COG0651	ATP synthesis coupled electron transport
OCC_RS09905	COG3260	NADH ubiquinone oxidoreductase 20
OCC_RS09910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS09920	COG0650	Formate hydrogenlyase subunit 4
OCC_RS09935	COG2212	antiporter activity
OCC_RS09940	COG1320	monovalent cation:proton antiporter activity
OCC_RS09960	COG1006	Multisubunit Na H antiporter MnhC subunit
OCC_RS09965	COG0651	ATP synthesis coupled electron transport
OCC_RS09975	COG3260	NADH ubiquinone oxidoreductase 20
OCC_RS09980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCC_RS09980	COG0649	NAD binding
OCC_RS09990	COG0650	Formate hydrogenlyase subunit 4
OCC_RS10020	COG0417	DNA replication proofreading
OCC_RS10025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCC_RS10025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCC_RS10035	COG2078	PFAM AMMECR1 domain protein
OCC_RS10040	COG0011	TIGRFAM Protein of
OCC_RS10080	COG0235	Class ii aldolase
OCC_RS10100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCC_RS10135	COG1196	nuclear chromosome segregation
OCC_RS10155	COG0483	inositol monophosphate 1-phosphatase activity
OCC_RS10165	COG1979	alcohol dehydrogenase
OCC_RS10175	COG1984	allophanate hydrolase subunit 2
OCC_RS10180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OCC_RS10195	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OCC_RS10210	COG0163	prenyltransferase activity
OCC_RS10225	COG0864	Transcriptional regulator
OCC_RS10265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OCC_RS10275	COG1765	OsmC-like protein
OCC_RS10305	COG0588	phosphoglycerate mutase activity
OCC_RS10340	COG0436	Aminotransferase
OCC_RS10345	COG2192	nodulation
OCC_RS10405	COG0148	phosphopyruvate hydratase activity
OCC_RS10415	COG1131	(ABC) transporter
OCC_RS10435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCC_RS10485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OCC_RS10485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OCC_RS10490	COG2140	Oxalate decarboxylase
OCC_RS10495	COG1994	Peptidase M50
OCC_RS10540	COG1288	antiporter activity
OCC_RS10550	COG1522	sequence-specific DNA binding
OCC_RS10560	COG1234	tRNA 3'-trailer cleavage
OCC_RS10580	COG0746	molybdenum cofactor guanylyltransferase activity
OCC_RS10595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCC_RS10620	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OCC_RS10630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OCC_RS10635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OCC_RS10640	COG0589	response to stress
OCC_RS10650	COG1402	creatininase
OCC_RS10655	COG0438	transferase activity, transferring glycosyl groups
OCC_RS10675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OCC_RS10680	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OCC_RS10700	COG0651	ATP synthesis coupled electron transport
OCC_RS10725	COG1320	monovalent cation:proton antiporter activity
OCC_RS10730	COG2212	antiporter activity
OCC_RS10735	COG1863	multisubunit Na H antiporter MnhE subunit
OCC_RS10755	COG0563	adenylate kinase activity
OCC_RS10760	COG0011	TIGRFAM Protein of
OCC_RS10765	COG2226	methyltransferase
OCC_RS10800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OCC_RS10805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCC_RS10835	COG1444	tRNA N-acetyltransferase activity
OCC_RS10840	COG0823	Involved in the tonB-independent uptake of proteins
OCC_RS10840	COG1506	peptidase
OCC_RS10840	COG4946	Tricorn protease homolog
OCC_RS10860	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCC_RS10875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCC_RS10895	COG1573	uracil-dna glycosylase
OCC_RS10900	COG1757	Na H antiporter
OCC_RS10920	COG1793	dna ligase
OCC_RS10940	COG0546	phosphoglycolate phosphatase activity
OCC_RS10950	COG0436	Aminotransferase
OCC_RS10960	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
OCC_RS10965	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OCC_RS10980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCC_RS11025	COG0543	2 iron, 2 sulfur cluster binding
OCC_RS11030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCC_RS11030	COG0493	'glutamate synthase
OCC_RS11035	COG2226	methyltransferase
OCC_RS11045	COG0312	modulator of DNA gyrase
OCC_RS11055	COG0312	modulator of DNA gyrase
OCC_RS11060	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCC_RS11065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCC_RS11130	COG0579	oxidoreductase
OCC_RS11150	COG0584	glycerophosphoryl diester phosphodiesterase
OCC_RS11165	COG1192	Involved in chromosome partitioning
OCC_RS11170	COG2211	Major facilitator Superfamily
OCC_RS11175	COG2211	Major facilitator Superfamily
OCC_RS11175	COG2190	(PTS) system
OCC_RS11195	COG1872	DUF167
OCC_RS11210	COG0423	glycine-tRNA ligase activity
OCC_RS11225	COG0420	3'-5' exonuclease activity
OCC_RS11235	COG1899	peptidyl-lysine modification to peptidyl-hypusine
OCC_RS11250	COG0303	'Molybdopterin
OCC_RS11260	COG2226	methyltransferase
OCC_RS11270	COG0525	valine-tRNA ligase activity
OCC_RS11295	COG0501	Belongs to the peptidase M48B family
OCC_RS11300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OCC_RS11305	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
OCC_RS11315	COG1515	deoxyribonuclease V activity
OCC_RS11335	COG0569	domain protein
OCC_RS11350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCC_RS11385	COG0017	Asparaginyl-tRNA synthetase
OCC_RS11400	COG0489	protein tyrosine kinase activity
OCC_RS11410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OCC_RS11415	COG1115	amino acid carrier protein
OCC_RS11430	COG2414	aldehyde ferredoxin oxidoreductase
OCC_RS11435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCC_RS11435	COG1213	nucleotidyl transferase
OCC_RS11440	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OCC_RS11455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OCC_RS11460	COG0442	prolyl-tRNA aminoacylation
OCC_RS11465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCC_RS11470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCC_RS11480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCC_RS11515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCC_RS11525	COG0006	proline dipeptidase activity
OCC_RS11530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCC_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
OCC_RS11580	COG0513	Belongs to the DEAD box helicase family
OCC_RS11625	COG1506	peptidase
OCC_RS11625	COG4946	Tricorn protease homolog
OCC_RS11625	COG0823	Involved in the tonB-independent uptake of proteins
OCC_RS11640	COG0747	negative chemotaxis
OCC_RS11645	COG0601	transmembrane transport
OCC_RS11650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCC_RS11655	COG0444	Belongs to the ABC transporter superfamily
OCC_RS11660	COG4608	Belongs to the ABC transporter superfamily
OCC_RS11670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OCC_RS11710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCC_RS11720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCC_RS11720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCC_RS11725	COG2271	Major facilitator Superfamily
OCC_RS11730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCC_RS11750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCC_RS11765	COG2264	protein methyltransferase activity
OCC_RS11820	COG0778	Nitroreductase
OCC_RS11855	COG1132	(ABC) transporter
OCC_RS11860	COG1132	(ABC) transporter
OCC_RS11870	COG1056	cytidyltransferase-related domain
OCC_RS11870	COG1051	belongs to the nudix hydrolase family
OCC_RS11920	COG0560	Phosphoserine phosphatase
OCC_RS11925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCC_RS11940	COG0175	sulfate reduction
OCC_RS11980	COG1469	GTP cyclohydrolase I activity
OCC_RS12005	COG2205	protein histidine kinase activity
OCC_RS12030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OCC_RS12045	COG0347	Belongs to the P(II) protein family
OCC_RS12050	COG1543	Belongs to the glycosyl hydrolase 57 family
OCC_RS12055	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OCC_RS12100	COG0697	spore germination
OCC_RS12110	COG2414	aldehyde ferredoxin oxidoreductase
OCC_RS12145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OCC_RS12210	COG2813	Specifically methylates the guanine in position
OCC_RS12305	COG0804	urea catabolic process
OCC_RS12310	COG0402	S-adenosylhomocysteine deaminase activity
OCC_RS12350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone