locus-tag	class	description
TON_RS00005	COG0417	DNA replication proofreading
TON_RS00005	COG0417	DNA replication proofreading
TON_RS00035	COG1185	polyribonucleotide nucleotidyltransferase activity
TON_RS00055	COG1695	Transcriptional regulator
TON_RS00060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TON_RS00060	COG2050	protein possibly involved in aromatic compounds catabolism
TON_RS00080	COG3842	ATPase activity
TON_RS00085	COG1335	isochorismatase
TON_RS00090	COG0628	permease
TON_RS00105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS00150	COG1185	polyribonucleotide nucleotidyltransferase activity
TON_RS00155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TON_RS00185	COG2239	Acts as a magnesium transporter
TON_RS00190	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TON_RS00195	COG0511	ligase activity, forming carbon-carbon bonds
TON_RS00195	COG5016	pyruvate
TON_RS00205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TON_RS00215	COG1372	Participates in initiation and elongation during chromosome replication
TON_RS00215	COG0305	Participates in initiation and elongation during chromosome replication
TON_RS00240	COG0430	RNA-3'-phosphate cyclase activity
TON_RS00270	COG0543	2 iron, 2 sulfur cluster binding
TON_RS00280	COG0543	2 iron, 2 sulfur cluster binding
TON_RS00285	COG0493	'glutamate synthase
TON_RS00285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TON_RS00290	COG0017	Asparaginyl-tRNA synthetase
TON_RS00305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TON_RS00330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TON_RS00335	COG0088	Forms part of the polypeptide exit tunnel
TON_RS00340	COG0089	rRNA binding
TON_RS00345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TON_RS00350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TON_RS00355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TON_RS00360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TON_RS00365	COG0255	Belongs to the universal ribosomal protein uL29 family
TON_RS00380	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TON_RS00385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TON_RS00400	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TON_RS00410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TON_RS00415	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TON_RS00430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TON_RS00435	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TON_RS00440	COG1841	ribosomal large subunit assembly
TON_RS00445	COG0200	Binds to the 23S rRNA
TON_RS00470	COG1102	Psort location Cytoplasmic, score
TON_RS00480	COG0300	oxidoreductase activity
TON_RS00485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TON_RS00520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TON_RS00525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TON_RS00535	COG0202	RNA polymerase activity
TON_RS00545	COG0200	Binds to the 23S rRNA
TON_RS00550	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TON_RS00555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TON_RS00580	COG0052	Belongs to the universal ribosomal protein uS2 family
TON_RS00620	COG1522	sequence-specific DNA binding
TON_RS00630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TON_RS00645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TON_RS00665	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TON_RS00670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TON_RS00690	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TON_RS00695	COG1355	regulation of microtubule-based process
TON_RS00700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TON_RS00710	COG1304	FMN binding
TON_RS00715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TON_RS00720	COG0142	geranyltranstransferase activity
TON_RS00745	COG0495	leucyl-tRNA aminoacylation
TON_RS00775	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TON_RS00790	COG0864	Transcriptional regulator
TON_RS00800	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TON_RS00805	COG1543	Belongs to the glycosyl hydrolase 57 family
TON_RS00810	COG0347	Belongs to the P(II) protein family
TON_RS00820	COG0733	neurotransmitter:sodium symporter activity
TON_RS00825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TON_RS00860	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TON_RS00865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TON_RS00880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TON_RS00895	COG1458	PINc domain ribonuclease
TON_RS00915	COG2358	TRAP transporter, solute receptor (TAXI family
TON_RS00925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TON_RS00940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TON_RS00945	COG0081	regulation of translation
TON_RS00970	COG0717	Belongs to the dCTP deaminase family
TON_RS00995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TON_RS01005	COG0058	SHG alpha-glucan phosphorylase activity
TON_RS01010	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TON_RS01025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TON_RS01045	COG0584	glycerophosphoryl diester phosphodiesterase
TON_RS01050	COG0584	glycerophosphoryl diester phosphodiesterase
TON_RS01060	COG0579	oxidoreductase
TON_RS01115	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TON_RS01150	COG0085	RNA polymerase activity
TON_RS01155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TON_RS01160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TON_RS01180	COG0049	tRNA binding
TON_RS01185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TON_RS01230	COG0436	Aminotransferase
TON_RS01260	COG1185	polyribonucleotide nucleotidyltransferase activity
TON_RS01275	COG0310	cobalt ion transport
TON_RS01290	COG1122	ATPase activity
TON_RS01310	COG2140	Oxalate decarboxylase
TON_RS01315	COG1994	Peptidase M50
TON_RS01330	COG1234	tRNA 3'-trailer cleavage
TON_RS01340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TON_RS01345	COG4139	cobalamin transport
TON_RS01350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TON_RS01380	COG0489	protein tyrosine kinase activity
TON_RS01390	COG0746	molybdenum cofactor guanylyltransferase activity
TON_RS01400	COG0651	ATP synthesis coupled electron transport
TON_RS01425	COG1320	monovalent cation:proton antiporter activity
TON_RS01440	COG3260	NADH ubiquinone oxidoreductase 20
TON_RS01445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS01450	COG3261	NADH dehydrogenase
TON_RS01450	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TON_RS01455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TON_RS01460	COG0651	ATP synthesis coupled electron transport
TON_RS01465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TON_RS01475	COG3383	formate dehydrogenase (NAD+) activity
TON_RS01495	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TON_RS01510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TON_RS01515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TON_RS01540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TON_RS01545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TON_RS01550	COG1120	ATPase activity
TON_RS01585	COG0446	pyridine nucleotide-disulphide oxidoreductase
TON_RS01600	COG1404	Belongs to the peptidase S8 family
TON_RS01615	COG0574	Belongs to the PEP-utilizing enzyme family
TON_RS01615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TON_RS01620	COG0534	Mate efflux family protein
TON_RS01625	COG0534	Mate efflux family protein
TON_RS01630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TON_RS01645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TON_RS01670	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TON_RS01725	COG1110	DNA topoisomerase II activity
TON_RS01750	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TON_RS01775	COG1418	mRNA catabolic process
TON_RS01785	COG0017	Asparaginyl-tRNA synthetase
TON_RS01800	COG0585	pseudouridine synthase activity
TON_RS01810	COG1473	amidohydrolase
TON_RS01845	COG0504	CTP synthase activity
TON_RS01865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TON_RS01880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TON_RS01890	COG0516	GMP reductase activity
TON_RS01890	COG0517	IMP dehydrogenase activity
TON_RS01900	COG0024	Methionine aminopeptidase
TON_RS01905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TON_RS01910	COG1122	ATPase activity
TON_RS01955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TON_RS01970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TON_RS01975	COG1185	polyribonucleotide nucleotidyltransferase activity
TON_RS02015	COG0628	permease
TON_RS02020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TON_RS02045	COG1131	(ABC) transporter
TON_RS02055	COG0556	nucleotide-excision repair
TON_RS02060	COG0101	tRNA pseudouridine synthase activity
TON_RS02070	COG0072	phenylalanine-tRNA ligase activity
TON_RS02080	COG1063	alcohol dehydrogenase
TON_RS02085	COG2894	cell division
TON_RS02100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TON_RS02105	COG0252	asparaginase activity
TON_RS02135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TON_RS02145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TON_RS02175	COG0438	transferase activity, transferring glycosyl groups
TON_RS02185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TON_RS02215	COG0010	Belongs to the arginase family
TON_RS02265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TON_RS02275	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TON_RS02285	COG1757	Na H antiporter
TON_RS02300	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TON_RS02305	COG0656	L-ascorbic acid biosynthetic process
TON_RS02325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TON_RS02325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TON_RS02340	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TON_RS02340	COG0359	binds to the 23S rRNA
TON_RS02380	COG0602	queuosine metabolic process
TON_RS02400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TON_RS02470	COG1151	hydroxylamine reductase activity
TON_RS02525	COG0649	NAD binding
TON_RS02530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS02535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS02540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TON_RS02545	COG0651	ATP synthesis coupled electron transport
TON_RS02550	COG0651	ATP synthesis coupled electron transport
TON_RS02555	COG1006	Multisubunit Na H antiporter MnhC subunit
TON_RS02560	COG2111	Na H antiporter
TON_RS02560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TON_RS02570	COG1320	monovalent cation:proton antiporter activity
TON_RS02575	COG2212	antiporter activity
TON_RS02580	COG1863	multisubunit Na H antiporter MnhE subunit
TON_RS02590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TON_RS02600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TON_RS02620	COG0018	arginyl-trna synthetase
TON_RS02625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TON_RS02680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TON_RS02700	COG0301	tRNA thio-modification
TON_RS02700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TON_RS02705	COG1836	PFAM Integral membrane protein DUF92
TON_RS02710	COG1522	sequence-specific DNA binding
TON_RS02720	COG0640	Transcriptional regulator
TON_RS02740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TON_RS02745	COG0396	ATPase activity
TON_RS02750	COG0719	Fe-S assembly protein
TON_RS02770	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
TON_RS02790	COG2116	formate transmembrane transporter activity
TON_RS02795	COG3383	formate dehydrogenase (NAD+) activity
TON_RS02805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS02810	COG0493	'glutamate synthase
TON_RS02815	COG0437	4 iron, 4 sulfur cluster binding
TON_RS02830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TON_RS02840	COG1476	TRANSCRIPTIONal
TON_RS02890	COG1515	deoxyribonuclease V activity
TON_RS02900	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TON_RS02910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TON_RS02925	COG0436	Aminotransferase
TON_RS02930	COG2192	nodulation
TON_RS02940	COG0442	prolyl-tRNA aminoacylation
TON_RS02945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TON_RS02955	COG0730	response to heat
TON_RS02965	COG0730	response to heat
TON_RS03000	COG0720	synthase
TON_RS03015	COG1013	pyruvate-flavodoxin oxidoreductase activity
TON_RS03020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TON_RS03020	COG0674	pyruvate-flavodoxin oxidoreductase activity
TON_RS03030	COG1013	pyruvate-flavodoxin oxidoreductase activity
TON_RS03035	COG0674	pyruvate-flavodoxin oxidoreductase activity
TON_RS03035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TON_RS03050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TON_RS03070	COG1744	ABC transporter substrate-binding protein PnrA-like
TON_RS03075	COG3845	ABC transporter
TON_RS03080	COG4603	Belongs to the binding-protein-dependent transport system permease family
TON_RS03085	COG1079	Belongs to the binding-protein-dependent transport system permease family
TON_RS03105	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TON_RS03110	COG0215	cysteine-tRNA ligase activity
TON_RS03130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TON_RS03135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TON_RS03140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TON_RS03140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TON_RS03145	COG0307	riboflavin synthase, alpha
TON_RS03150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TON_RS03150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TON_RS03155	COG1505	serine-type exopeptidase activity
TON_RS03160	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TON_RS03165	COG1201	RNA secondary structure unwinding
TON_RS03165	COG1201	RNA secondary structure unwinding
TON_RS03180	COG0306	phosphate transporter
TON_RS03240	COG1363	Peptidase, m42
TON_RS03275	COG2096	Adenosyltransferase
TON_RS03285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TON_RS03290	COG1546	Belongs to the CinA family
TON_RS03290	COG1058	Belongs to the CinA family
TON_RS03300	COG0814	amino acid
TON_RS03305	COG1872	DUF167
TON_RS03315	COG0423	glycine-tRNA ligase activity
TON_RS03330	COG0534	Mate efflux family protein
TON_RS03340	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TON_RS03355	COG0006	proline dipeptidase activity
TON_RS03370	COG0482	sulfurtransferase activity
TON_RS03395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TON_RS03430	COG0012	GTP binding
TON_RS03450	COG0312	modulator of DNA gyrase
TON_RS03460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TON_RS03485	COG0525	valine-tRNA ligase activity
TON_RS03495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TON_RS03500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TON_RS03525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TON_RS03530	COG2342	PFAM TM1410 hypothetical-related protein
TON_RS03535	COG0746	molybdenum cofactor guanylyltransferase activity
TON_RS03540	COG1492	cobalamin metabolic process
TON_RS03545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TON_RS03560	COG0303	'Molybdopterin
TON_RS03585	COG1078	dGTPase activity
TON_RS03610	COG1899	peptidyl-lysine modification to peptidyl-hypusine
TON_RS03640	COG0459	protein refolding
TON_RS03650	COG0515	serine threonine protein kinase
TON_RS03655	COG0840	transmembrane signaling receptor activity
TON_RS03660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TON_RS03670	COG0315	cyclic pyranopterin monophosphate synthase activity
TON_RS03700	COG1215	transferase activity, transferring glycosyl groups
TON_RS03735	COG1739	Uncharacterized protein family UPF0029
TON_RS03740	COG1205	dead DEAH box helicase
TON_RS03740	COG1111	helicase
TON_RS03750	COG1121	(ABC) transporter
TON_RS03830	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
TON_RS03855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TON_RS03860	COG2414	aldehyde ferredoxin oxidoreductase
TON_RS03875	COG0051	transcription antitermination factor activity, RNA binding
TON_RS03880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TON_RS03890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TON_RS03895	COG1078	dGTPase activity
TON_RS03900	COG1469	GTP cyclohydrolase I activity
TON_RS03930	COG2205	protein histidine kinase activity
TON_RS03950	COG1121	(ABC) transporter
TON_RS03960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TON_RS03980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TON_RS03995	COG2226	methyltransferase
TON_RS04025	COG0531	amino acid
TON_RS04040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TON_RS04085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TON_RS04090	COG1993	acr, cog1993
TON_RS04105	COG0668	transmembrane transport
TON_RS04115	COG1794	racemase activity, acting on amino acids and derivatives
TON_RS04130	COG0312	modulator of DNA gyrase
TON_RS04135	COG0312	modulator of DNA gyrase
TON_RS04145	COG0477	Major facilitator Superfamily
TON_RS04180	COG0438	transferase activity, transferring glycosyl groups
TON_RS04195	COG0546	phosphoglycolate phosphatase activity
TON_RS04205	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TON_RS04215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TON_RS04250	COG0243	molybdopterin cofactor binding
TON_RS04255	COG0450	alkyl hydroperoxide reductase
TON_RS04280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TON_RS04285	COG2217	Heavy metal translocating P-type atpase
TON_RS04300	COG2226	methyltransferase
TON_RS04310	COG2217	Heavy metal translocating P-type atpase
TON_RS04345	COG0450	alkyl hydroperoxide reductase
TON_RS04365	COG0396	ATPase activity
TON_RS04375	COG0301	tRNA thio-modification
TON_RS04380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TON_RS04385	COG0778	Nitroreductase
TON_RS04410	COG1013	pyruvate-flavodoxin oxidoreductase activity
TON_RS04415	COG0450	alkyl hydroperoxide reductase
TON_RS04420	COG0426	domain, Protein
TON_RS04435	COG1592	Rubrerythrin
TON_RS04440	COG1773	rubredoxin
TON_RS04445	COG2033	superoxide reductase activity
TON_RS04500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TON_RS04510	COG0131	Imidazoleglycerol-phosphate dehydratase
TON_RS04515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TON_RS04525	COG0107	imidazoleglycerol-phosphate synthase activity
TON_RS04530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TON_RS04530	COG0140	phosphoribosyl-ATP diphosphatase activity
TON_RS04535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TON_RS04545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TON_RS04550	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TON_RS04570	COG1353	crispr-associated protein
TON_RS04580	COG1337	RAMP superfamily
TON_RS04600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TON_RS04610	COG1301	dicarboxylic acid transport
TON_RS04630	COG1966	Carbon starvation protein
TON_RS04655	COG2267	carboxylic ester hydrolase activity
TON_RS04660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TON_RS04685	COG0489	protein tyrosine kinase activity
TON_RS04740	COG1342	Belongs to the UPF0251 family
TON_RS04745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TON_RS04770	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TON_RS04785	COG1201	RNA secondary structure unwinding
TON_RS04790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TON_RS04795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TON_RS04805	COG0084	hydrolase, TatD family'
TON_RS04825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TON_RS04830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TON_RS04835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TON_RS04840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TON_RS04850	COG0105	UTP biosynthetic process
TON_RS04880	COG0175	sulfate reduction
TON_RS04895	COG0402	S-adenosylhomocysteine deaminase activity
TON_RS04900	COG0017	Asparaginyl-tRNA synthetase
TON_RS04915	COG4143	(ABC) transporter
TON_RS04940	COG1444	tRNA N-acetyltransferase activity
TON_RS04945	COG0823	Involved in the tonB-independent uptake of proteins
TON_RS04945	COG4946	Tricorn protease homolog
TON_RS04945	COG1506	peptidase
TON_RS04965	COG1268	BioY protein
TON_RS04970	COG1122	ATPase activity
TON_RS04975	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TON_RS05000	COG1522	sequence-specific DNA binding
TON_RS05020	COG1178	ABC-type Fe3 transport system permease component
TON_RS05025	COG3842	ATPase activity
TON_RS05035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TON_RS05050	COG0126	phosphoglycerate kinase activity
TON_RS05080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TON_RS05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TON_RS05110	COG0045	succinate-CoA ligase (ADP-forming) activity
TON_RS05110	COG1042	CoA-binding domain protein
TON_RS05120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TON_RS05130	COG0301	tRNA thio-modification
TON_RS05140	COG0301	tRNA thio-modification
TON_RS05155	COG3473	Maleate cis-trans isomerase
TON_RS05190	COG0437	4 iron, 4 sulfur cluster binding
TON_RS05200	COG2894	cell division
TON_RS05210	COG0651	ATP synthesis coupled electron transport
TON_RS05215	COG0650	Formate hydrogenlyase subunit 4
TON_RS05220	COG3261	NADH dehydrogenase
TON_RS05220	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TON_RS05230	COG3260	NADH ubiquinone oxidoreductase 20
TON_RS05240	COG1320	monovalent cation:proton antiporter activity
TON_RS05250	COG2111	Na H antiporter
TON_RS05255	COG1006	Multisubunit Na H antiporter MnhC subunit
TON_RS05265	COG0651	ATP synthesis coupled electron transport
TON_RS05310	COG1199	ATP-dependent helicase activity
TON_RS05330	COG0513	Belongs to the DEAD box helicase family
TON_RS05350	COG0483	inositol monophosphate 1-phosphatase activity
TON_RS05360	COG1979	alcohol dehydrogenase
TON_RS05370	COG1984	allophanate hydrolase subunit 2
TON_RS05375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TON_RS05380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TON_RS05400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TON_RS05415	COG0330	HflC and HflK could
TON_RS05420	COG2894	cell division
TON_RS05435	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TON_RS05450	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TON_RS05470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TON_RS05480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TON_RS05485	COG1196	nuclear chromosome segregation
TON_RS05495	COG0346	lactoylglutathione lyase activity
TON_RS05505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TON_RS05505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TON_RS05515	COG0424	maF-like protein
TON_RS05520	COG4956	integral membrane protein (PIN domain superfamily)
TON_RS05525	COG2894	cell division
TON_RS05535	COG0367	asparagine synthase
TON_RS05550	COG0009	L-threonylcarbamoyladenylate synthase
TON_RS05570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TON_RS05575	COG0303	'Molybdopterin
TON_RS05585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TON_RS05600	COG0045	succinate-CoA ligase (ADP-forming) activity
TON_RS05600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TON_RS05600	COG1042	CoA-binding domain protein
TON_RS05665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TON_RS05665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TON_RS05680	COG0071	Belongs to the small heat shock protein (HSP20) family
TON_RS05735	COG0778	Nitroreductase
TON_RS05755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TON_RS05760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TON_RS05765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TON_RS05770	COG0710	3-dehydroquinate dehydratase activity
TON_RS05775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TON_RS05785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TON_RS05795	COG1605	Chorismate mutase
TON_RS05795	COG0077	Prephenate dehydratase
TON_RS05800	COG0436	Aminotransferase
TON_RS05865	COG2226	methyltransferase
TON_RS05890	COG0560	Phosphoserine phosphatase
TON_RS05900	COG1056	cytidyltransferase-related domain
TON_RS05900	COG1051	belongs to the nudix hydrolase family
TON_RS05920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TON_RS05950	COG0560	Phosphoserine phosphatase
TON_RS05955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TON_RS06025	COG2264	protein methyltransferase activity
TON_RS06040	COG0835	chemotaxis
TON_RS06045	COG0840	transmembrane signaling receptor activity
TON_RS06055	COG2201	protein-glutamate methylesterase activity
TON_RS06060	COG2201	protein-glutamate methylesterase activity
TON_RS06065	COG0643	Histidine kinase
TON_RS06065	COG2198	Histidine kinase
TON_RS06080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TON_RS06135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TON_RS06140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TON_RS06165	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TON_RS06170	COG0432	Pfam Uncharacterised protein family UPF0047
TON_RS06220	COG2379	hydroxypyruvate reductase
TON_RS06240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TON_RS06245	COG1435	thymidine kinase activity
TON_RS06250	COG1850	ribulose-bisphosphate carboxylase activity
TON_RS06295	COG1131	(ABC) transporter
TON_RS06315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TON_RS06315	COG1213	nucleotidyl transferase
TON_RS06330	COG0284	orotidine-5'-phosphate decarboxylase activity
TON_RS06340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TON_RS06340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TON_RS06350	COG1192	Involved in chromosome partitioning
TON_RS06355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TON_RS06370	COG0436	Aminotransferase
TON_RS06375	COG2119	membrane
TON_RS06400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TON_RS06405	COG0167	dihydroorotate dehydrogenase activity
TON_RS06430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TON_RS06440	COG0528	UMP kinase activity
TON_RS06445	COG0446	pyridine nucleotide-disulphide oxidoreductase
TON_RS06455	COG0501	Belongs to the peptidase M48B family
TON_RS06470	COG2814	Major facilitator Superfamily
TON_RS06475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TON_RS06490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TON_RS06495	COG1522	sequence-specific DNA binding
TON_RS06500	COG0693	protein deglycase activity
TON_RS06530	COG2095	MarC family integral membrane protein
TON_RS06535	COG1765	OsmC-like protein
TON_RS06545	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TON_RS06550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TON_RS06555	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TON_RS06580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TON_RS06625	COG0123	including yeast histone deacetylase and acetoin utilization protein
TON_RS06645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TON_RS06680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TON_RS06685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TON_RS06700	COG0440	acetolactate synthase activity
TON_RS06705	COG0651	ATP synthesis coupled electron transport
TON_RS06730	COG1320	monovalent cation:proton antiporter activity
TON_RS06735	COG2212	antiporter activity
TON_RS06740	COG1863	multisubunit Na H antiporter MnhE subunit
TON_RS06745	COG0509	glycine decarboxylation via glycine cleavage system
TON_RS06755	COG0493	'glutamate synthase
TON_RS06760	COG0543	2 iron, 2 sulfur cluster binding
TON_RS06815	COG1131	(ABC) transporter
TON_RS06825	COG1476	TRANSCRIPTIONal
TON_RS06850	COG0535	radical SAM domain protein
TON_RS06855	COG2414	aldehyde ferredoxin oxidoreductase
TON_RS06860	COG1404	Belongs to the peptidase S8 family
TON_RS06885	COG2151	metal-sulfur cluster biosynthetic enzyme
TON_RS06890	COG1141	Ferredoxin
TON_RS06925	COG2131	deaminase
TON_RS06930	COG0501	Belongs to the peptidase M48B family
TON_RS06965	COG0543	2 iron, 2 sulfur cluster binding
TON_RS06970	COG0493	'glutamate synthase
TON_RS07040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TON_RS07045	COG0477	Major facilitator Superfamily
TON_RS07070	COG2814	Major facilitator Superfamily
TON_RS07075	COG1446	asparaginase
TON_RS07100	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TON_RS07150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TON_RS07175	COG1530	ribonuclease E activity
TON_RS07185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TON_RS07205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TON_RS07210	COG0156	8-amino-7-oxononanoate synthase activity
TON_RS07225	COG0456	acetyltransferase
TON_RS07225	COG1214	PFAM Peptidase M22, glycoprotease
TON_RS07235	COG0433	COG0433 Predicted ATPase
TON_RS07245	COG0419	ATPase involved in DNA repair
TON_RS07245	COG0419	ATPase involved in DNA repair
TON_RS07255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TON_RS07260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TON_RS07265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TON_RS07275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TON_RS07290	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TON_RS07315	COG0351	phosphomethylpyrimidine kinase
TON_RS07315	COG1992	Thiamine-phosphate synthase
TON_RS07320	COG0540	Belongs to the ATCase OTCase family
TON_RS07325	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TON_RS07365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TON_RS07385	COG0434	BtpA family
TON_RS07410	COG0312	modulator of DNA gyrase
TON_RS07415	COG0640	Transcriptional regulator
TON_RS07460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TON_RS07475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TON_RS07495	COG0475	glutathione-regulated potassium exporter activity
TON_RS07515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TON_RS07520	COG0306	phosphate transporter
TON_RS07535	COG0674	pyruvate-flavodoxin oxidoreductase activity
TON_RS07540	COG1013	pyruvate-flavodoxin oxidoreductase activity
TON_RS07550	COG0674	pyruvate-flavodoxin oxidoreductase activity
TON_RS07555	COG1013	pyruvate-flavodoxin oxidoreductase activity
TON_RS07560	COG0489	protein tyrosine kinase activity
TON_RS07585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TON_RS07595	COG1254	Belongs to the acylphosphatase family
TON_RS07605	COG1628	Protein of unknown function DUF99
TON_RS07610	COG0589	response to stress
TON_RS07615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TON_RS07635	COG1980	fructose-bisphosphate aldolase activity
TON_RS07655	COG1233	COG1233 Phytoene dehydrogenase and related
TON_RS07710	COG1522	sequence-specific DNA binding
TON_RS07715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TON_RS07730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TON_RS07750	COG1757	Na H antiporter
TON_RS07755	COG1573	uracil-dna glycosylase
TON_RS07765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TON_RS07780	COG1380	Effector of murein hydrolase LrgA
TON_RS07785	COG1346	cytolysis
TON_RS07815	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TON_RS07840	COG0095	Lipoate-protein ligase
TON_RS07845	COG0681	Belongs to the peptidase S26 family
TON_RS07895	COG4946	Tricorn protease homolog
TON_RS07895	COG1506	peptidase
TON_RS07895	COG0823	Involved in the tonB-independent uptake of proteins
TON_RS07930	COG0306	phosphate transporter
TON_RS07955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TON_RS07965	COG3259	Nickel-dependent hydrogenase
TON_RS07980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TON_RS07985	COG3383	formate dehydrogenase (NAD+) activity
TON_RS07990	COG0437	4 iron, 4 sulfur cluster binding
TON_RS07995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TON_RS08000	COG0651	ATP synthesis coupled electron transport
TON_RS08005	COG0651	ATP synthesis coupled electron transport
TON_RS08010	COG0650	Formate hydrogenlyase subunit 4
TON_RS08015	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TON_RS08015	COG3261	NADH dehydrogenase
TON_RS08020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TON_RS08025	COG3260	NADH ubiquinone oxidoreductase 20
TON_RS08035	COG2116	formate transmembrane transporter activity
TON_RS08045	COG1320	monovalent cation:proton antiporter activity
TON_RS08055	COG2111	Na H antiporter
TON_RS08060	COG1006	Multisubunit Na H antiporter MnhC subunit
TON_RS08070	COG0651	ATP synthesis coupled electron transport
TON_RS08075	COG0746	molybdenum cofactor guanylyltransferase activity
TON_RS08080	COG1863	multisubunit Na H antiporter MnhE subunit
TON_RS08085	COG2212	antiporter activity
TON_RS08090	COG1320	monovalent cation:proton antiporter activity
TON_RS08115	COG0651	ATP synthesis coupled electron transport
TON_RS08125	COG3260	NADH ubiquinone oxidoreductase 20
TON_RS08130	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TON_RS08130	COG3261	NADH dehydrogenase
TON_RS08140	COG0650	Formate hydrogenlyase subunit 4
TON_RS08185	COG0492	ferredoxin-NADP+ reductase activity
TON_RS08195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TON_RS08210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TON_RS08225	COG2814	Major facilitator Superfamily
TON_RS08235	COG0148	phosphopyruvate hydratase activity
TON_RS08245	COG1522	sequence-specific DNA binding
TON_RS08250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TON_RS08270	COG0314	molybdopterin synthase activity
TON_RS08280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TON_RS08320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TON_RS08320	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TON_RS08330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TON_RS08340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TON_RS08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TON_RS08425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TON_RS08435	COG0402	S-adenosylhomocysteine deaminase activity
TON_RS08445	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TON_RS08445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TON_RS08465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TON_RS08465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TON_RS08485	COG0640	Transcriptional regulator
TON_RS08490	COG0490	domain, Protein
TON_RS08490	COG0471	metal ion transport
TON_RS08500	COG0180	Tryptophanyl-tRNA synthetase
TON_RS08505	COG0179	Fumarylacetoacetate (FAA) hydrolase
TON_RS08525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TON_RS08525	COG0116	Belongs to the methyltransferase superfamily
TON_RS08530	COG1160	GTP binding
TON_RS08565	COG1047	Peptidyl-prolyl cis-trans
TON_RS08590	COG0714	Associated with various cellular activities
TON_RS08605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TON_RS08610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TON_RS08620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TON_RS08625	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TON_RS08645	COG0750	zinc metalloprotease
TON_RS08650	COG1216	Glycosyl transferase, family 2
TON_RS08650	COG0463	Glycosyl transferase, family 2
TON_RS08655	COG3119	arylsulfatase activity
TON_RS08670	COG0110	maltose O-acetyltransferase activity
TON_RS08675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TON_RS08680	COG1086	Polysaccharide biosynthesis protein
TON_RS08695	COG0730	response to heat
TON_RS08700	COG0529	Catalyzes the synthesis of activated sulfate
TON_RS08715	COG2046	Belongs to the sulfate adenylyltransferase family
TON_RS08725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TON_RS08760	COG1449	Belongs to the glycosyl hydrolase 57 family
TON_RS08765	COG0037	tRNA processing
TON_RS08775	COG2239	Acts as a magnesium transporter
TON_RS08780	COG0475	glutathione-regulated potassium exporter activity
TON_RS08815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TON_RS08830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TON_RS08870	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TON_RS08880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TON_RS08895	COG0569	domain protein
TON_RS08905	COG1269	ATP hydrolysis coupled proton transport
TON_RS08915	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TON_RS08925	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TON_RS08930	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TON_RS08945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TON_RS08945	COG0426	domain, Protein
TON_RS08950	COG5278	phosphoserine phosphatase activity
TON_RS08950	COG0840	transmembrane signaling receptor activity
TON_RS08955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TON_RS08960	COG0482	sulfurtransferase activity
TON_RS08980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TON_RS08990	COG0601	transmembrane transport
TON_RS08995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TON_RS09000	COG0444	Belongs to the ABC transporter superfamily
TON_RS09005	COG4608	Belongs to the ABC transporter superfamily
TON_RS09025	COG0174	glutamine synthetase
TON_RS09045	COG0697	spore germination
TON_RS09060	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TON_RS09080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TON_RS09090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TON_RS09100	COG1297	OPT oligopeptide transporter protein
TON_RS09105	COG1234	tRNA 3'-trailer cleavage
TON_RS09110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TON_RS09120	COG3842	ATPase activity
TON_RS09130	COG3833	ABC-type maltose transport systems, permease component
TON_RS09135	COG1175	transmembrane transport
TON_RS09140	COG2182	Extracellular solute-binding protein
TON_RS09150	COG1378	Sugar-specific transcriptional regulator TrmB
TON_RS09155	COG0297	glycogen (starch) synthase activity
TON_RS09190	COG0697	spore germination
TON_RS09200	COG2414	aldehyde ferredoxin oxidoreductase
TON_RS09230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TON_RS09245	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TON_RS09270	COG0438	transferase activity, transferring glycosyl groups
TON_RS09330	COG0714	Associated with various cellular activities
TON_RS09360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TON_RS09450	COG0297	glycogen (starch) synthase activity
TON_RS09450	COG0438	transferase activity, transferring glycosyl groups
TON_RS09460	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TON_RS09465	COG0438	transferase activity, transferring glycosyl groups
TON_RS09480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TON_RS09490	COG1216	Glycosyl transferase, family 2
TON_RS09560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TON_RS09565	COG1120	ATPase activity
TON_RS09575	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TON_RS09580	COG0459	protein refolding
TON_RS09615	COG0516	GMP reductase activity
TON_RS09615	COG0517	IMP dehydrogenase activity
TON_RS09620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TON_RS09630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TON_RS09640	COG0157	Belongs to the NadC ModD family
TON_RS09655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TON_RS09655	COG0519	Catalyzes the synthesis of GMP from XMP
TON_RS09660	COG0519	Catalyzes the synthesis of GMP from XMP
TON_RS09660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TON_RS09720	COG2264	protein methyltransferase activity
TON_RS09755	COG0539	negative regulation of cytoplasmic translation
TON_RS09790	COG2234	aminopeptidase activity
TON_RS09815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TON_RS09855	COG1695	Transcriptional regulator
TON_RS09865	COG0393	Putative heavy-metal-binding
TON_RS09875	COG2264	protein methyltransferase activity
TON_RS09895	COG0668	transmembrane transport
TON_RS09940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TON_RS09945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TON_RS09955	COG0109	protoheme IX farnesyltransferase activity
TON_RS10005	COG2252	PERMEase
TON_RS10010	COG3842	ATPase activity
TON_RS10015	COG1178	ABC-type Fe3 transport system permease component
TON_RS10040	COG0011	TIGRFAM Protein of
TON_RS10045	COG2078	PFAM AMMECR1 domain protein
TON_RS10050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TON_RS10050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TON_RS10100	COG0730	response to heat
TON_RS10145	COG0535	radical SAM domain protein
TON_RS10225	COG2813	Specifically methylates the guanine in position
TON_RS10245	COG0598	Magnesium transport protein CorA