locus-tag	class	description
TES1_RS00030	COG0714	Associated with various cellular activities
TES1_RS00065	COG0647	UMP catabolic process
TES1_RS00095	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TES1_RS00100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TES1_RS00175	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
TES1_RS00205	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TES1_RS00215	COG0347	Belongs to the P(II) protein family
TES1_RS00225	COG0733	neurotransmitter:sodium symporter activity
TES1_RS00230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TES1_RS00240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TES1_RS00245	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TES1_RS00260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TES1_RS00270	COG0022	dehydrogenase e1 component
TES1_RS00275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TES1_RS00280	COG0508	dehydrogenase complex catalyzes the overall conversion of
TES1_RS00285	COG0508	dehydrogenase complex catalyzes the overall conversion of
TES1_RS00295	COG3199	ATP-NAD kinase
TES1_RS00300	COG0095	Lipoate-protein ligase
TES1_RS00310	COG0534	Mate efflux family protein
TES1_RS00315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TES1_RS00315	COG0574	Belongs to the PEP-utilizing enzyme family
TES1_RS00335	COG1473	amidohydrolase
TES1_RS00340	COG1404	Belongs to the peptidase S8 family
TES1_RS00375	COG0446	pyridine nucleotide-disulphide oxidoreductase
TES1_RS00385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TES1_RS00415	COG1618	nucleotide phosphatase activity, acting on free nucleotides
TES1_RS00420	COG1120	ATPase activity
TES1_RS00425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TES1_RS00430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TES1_RS00445	COG0731	radical SAM domain protein
TES1_RS00445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_RS00465	COG0409	Hydrogenase expression formation protein
TES1_RS00480	COG3383	formate dehydrogenase (NAD+) activity
TES1_RS00490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TES1_RS00495	COG0651	ATP synthesis coupled electron transport
TES1_RS00500	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TES1_RS00505	COG3261	NADH dehydrogenase
TES1_RS00505	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TES1_RS00510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS00515	COG3260	NADH ubiquinone oxidoreductase 20
TES1_RS00530	COG1320	monovalent cation:proton antiporter activity
TES1_RS00545	COG1006	Multisubunit Na H antiporter MnhC subunit
TES1_RS00555	COG0651	ATP synthesis coupled electron transport
TES1_RS00570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TES1_RS00575	COG1120	ATPase activity
TES1_RS00585	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TES1_RS00600	COG1063	alcohol dehydrogenase
TES1_RS00605	COG0746	molybdenum cofactor guanylyltransferase activity
TES1_RS00620	COG1234	tRNA 3'-trailer cleavage
TES1_RS00635	COG1994	Peptidase M50
TES1_RS00640	COG2140	Oxalate decarboxylase
TES1_RS00675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TES1_RS00695	COG1122	ATPase activity
TES1_RS00710	COG0310	cobalt ion transport
TES1_RS00720	COG0025	NhaP-type Na H and K H
TES1_RS00725	COG0010	Belongs to the arginase family
TES1_RS00745	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TES1_RS00755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TES1_RS00755	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TES1_RS00760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TES1_RS00780	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TES1_RS00790	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TES1_RS00810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TES1_RS00820	COG0017	Asparaginyl-tRNA synthetase
TES1_RS00825	COG0778	Nitroreductase
TES1_RS00830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TES1_RS00830	COG0493	'glutamate synthase
TES1_RS00835	COG0543	2 iron, 2 sulfur cluster binding
TES1_RS00845	COG0543	2 iron, 2 sulfur cluster binding
TES1_RS00855	COG3259	Nickel-dependent hydrogenase
TES1_RS00885	COG0430	RNA-3'-phosphate cyclase activity
TES1_RS00915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TES1_RS00925	COG5016	pyruvate
TES1_RS00925	COG0511	ligase activity, forming carbon-carbon bonds
TES1_RS00930	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TES1_RS00935	COG2239	Acts as a magnesium transporter
TES1_RS00940	COG0460	homoserine dehydrogenase
TES1_RS00975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TES1_RS00985	COG0089	rRNA binding
TES1_RS00990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TES1_RS00995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TES1_RS01005	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TES1_RS01010	COG0255	Belongs to the universal ribosomal protein uL29 family
TES1_RS01015	COG0023	Translation Initiation Factor
TES1_RS01025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TES1_RS01030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TES1_RS01035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TES1_RS01045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TES1_RS01055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TES1_RS01060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TES1_RS01075	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TES1_RS01080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TES1_RS01085	COG1841	ribosomal large subunit assembly
TES1_RS01090	COG0200	Binds to the 23S rRNA
TES1_RS01115	COG1102	Psort location Cytoplasmic, score
TES1_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
TES1_RS01130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TES1_RS01145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TES1_RS01150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TES1_RS01155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TES1_RS01160	COG0202	RNA polymerase activity
TES1_RS01170	COG0200	Binds to the 23S rRNA
TES1_RS01175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TES1_RS01180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TES1_RS01200	COG0148	phosphopyruvate hydratase activity
TES1_RS01205	COG0052	Belongs to the universal ribosomal protein uS2 family
TES1_RS01210	COG1355	regulation of microtubule-based process
TES1_RS01220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TES1_RS01225	COG1304	FMN binding
TES1_RS01230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TES1_RS01245	COG0495	leucyl-tRNA aminoacylation
TES1_RS01270	COG0626	cystathionine gamma-synthase activity
TES1_RS01295	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TES1_RS01305	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TES1_RS01320	COG1185	polyribonucleotide nucleotidyltransferase activity
TES1_RS01325	COG1185	polyribonucleotide nucleotidyltransferase activity
TES1_RS01370	COG0359	binds to the 23S rRNA
TES1_RS01370	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TES1_RS01385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TES1_RS01385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TES1_RS01390	COG0656	L-ascorbic acid biosynthetic process
TES1_RS01400	COG1458	PINc domain ribonuclease
TES1_RS01420	COG2358	TRAP transporter, solute receptor (TAXI family
TES1_RS01435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TES1_RS01455	COG0081	regulation of translation
TES1_RS01475	COG0717	Belongs to the dCTP deaminase family
TES1_RS01505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TES1_RS01515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TES1_RS01520	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TES1_RS01535	COG0058	SHG alpha-glucan phosphorylase activity
TES1_RS01545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TES1_RS01560	COG2271	Major facilitator Superfamily
TES1_RS01565	COG2211	Major facilitator Superfamily
TES1_RS01570	COG0584	glycerophosphoryl diester phosphodiesterase
TES1_RS01575	COG0584	glycerophosphoryl diester phosphodiesterase
TES1_RS01595	COG0579	oxidoreductase
TES1_RS01645	COG0288	reversible hydration of carbon dioxide
TES1_RS01660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TES1_RS01700	COG0085	RNA polymerase activity
TES1_RS01705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TES1_RS01710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TES1_RS01730	COG0049	tRNA binding
TES1_RS01735	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TES1_RS01755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TES1_RS01760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TES1_RS01775	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TES1_RS01790	COG0477	Major facilitator Superfamily
TES1_RS01795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TES1_RS01810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TES1_RS01820	COG1522	sequence-specific DNA binding
TES1_RS01845	COG1695	Transcriptional regulator
TES1_RS01900	COG0003	Pfam Anion-transporting ATPase
TES1_RS01910	COG1966	Carbon starvation protein
TES1_RS01915	COG5016	pyruvate
TES1_RS01915	COG0511	ligase activity, forming carbon-carbon bonds
TES1_RS01920	COG1830	Aldolase
TES1_RS01925	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TES1_RS01925	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TES1_RS01940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TES1_RS01945	COG1872	DUF167
TES1_RS01955	COG0423	glycine-tRNA ligase activity
TES1_RS01975	COG0534	Mate efflux family protein
TES1_RS01985	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TES1_RS01995	COG0006	proline dipeptidase activity
TES1_RS02005	COG0709	Synthesizes selenophosphate from selenide and ATP
TES1_RS02025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TES1_RS02025	COG1918	ferrous iron import across plasma membrane
TES1_RS02035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TES1_RS02045	COG0163	prenyltransferase activity
TES1_RS02050	COG1522	sequence-specific DNA binding
TES1_RS02070	COG0012	GTP binding
TES1_RS02085	COG0598	Magnesium transport protein CorA
TES1_RS02105	COG0312	modulator of DNA gyrase
TES1_RS02110	COG0312	modulator of DNA gyrase
TES1_RS02120	COG1011	Hydrolase
TES1_RS02130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TES1_RS02160	COG0243	molybdopterin cofactor binding
TES1_RS02165	COG0450	alkyl hydroperoxide reductase
TES1_RS02190	COG1013	pyruvate-flavodoxin oxidoreductase activity
TES1_RS02195	COG0450	alkyl hydroperoxide reductase
TES1_RS02200	COG0426	domain, Protein
TES1_RS02205	COG0446	pyridine nucleotide-disulphide oxidoreductase
TES1_RS02210	COG1592	Rubrerythrin
TES1_RS02215	COG1773	rubredoxin
TES1_RS02220	COG2033	superoxide reductase activity
TES1_RS02250	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TES1_RS02305	COG1185	polyribonucleotide nucleotidyltransferase activity
TES1_RS02330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TES1_RS02355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TES1_RS02390	COG0252	asparaginase activity
TES1_RS02395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TES1_RS02415	COG2894	cell division
TES1_RS02425	COG1063	alcohol dehydrogenase
TES1_RS02445	COG0101	tRNA pseudouridine synthase activity
TES1_RS02450	COG0556	nucleotide-excision repair
TES1_RS02460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TES1_RS02470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TES1_RS02475	COG0083	homoserine kinase activity
TES1_RS02480	COG0527	aspartate kinase activity
TES1_RS02490	COG3959	Transketolase, thiamine diphosphate binding domain
TES1_RS02495	COG3958	Transketolase
TES1_RS02500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TES1_RS02515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TES1_RS02520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TES1_RS02525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TES1_RS02540	COG0436	Aminotransferase
TES1_RS02550	COG2217	Heavy metal translocating P-type atpase
TES1_RS02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TES1_RS02565	COG0347	Belongs to the P(II) protein family
TES1_RS02570	COG0004	ammonium transporteR
TES1_RS02575	COG0137	argininosuccinate synthase activity
TES1_RS02580	COG0165	Argininosuccinate lyase
TES1_RS02585	COG0505	Belongs to the CarA family
TES1_RS02595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TES1_RS02600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TES1_RS02605	COG0066	3-isopropylmalate dehydratase activity
TES1_RS02610	COG0473	3-isopropylmalate dehydrogenase activity
TES1_RS02620	COG0189	ligase activity
TES1_RS02625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TES1_RS02635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TES1_RS02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TES1_RS02650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TES1_RS02655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TES1_RS02655	COG0140	phosphoribosyl-ATP diphosphatase activity
TES1_RS02660	COG0107	imidazoleglycerol-phosphate synthase activity
TES1_RS02665	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TES1_RS02670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TES1_RS02675	COG0131	Imidazoleglycerol-phosphate dehydratase
TES1_RS02685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TES1_RS02705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TES1_RS02725	COG3842	ATPase activity
TES1_RS02730	COG0395	ABC-type sugar transport system, permease component
TES1_RS02735	COG1175	transmembrane transport
TES1_RS02745	COG2182	Extracellular solute-binding protein
TES1_RS02785	COG0725	ABC transporter, periplasmic molybdate-binding protein
TES1_RS02790	COG4149	molybdate abc transporter
TES1_RS02795	COG3842	ATPase activity
TES1_RS02805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TES1_RS02810	COG1058	Belongs to the CinA family
TES1_RS02810	COG1546	Belongs to the CinA family
TES1_RS02815	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TES1_RS02830	COG1993	acr, cog1993
TES1_RS02835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TES1_RS02910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TES1_RS02915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TES1_RS02925	COG0156	8-amino-7-oxononanoate synthase activity
TES1_RS02940	COG0456	acetyltransferase
TES1_RS02940	COG1214	PFAM Peptidase M22, glycoprotease
TES1_RS02945	COG0433	COG0433 Predicted ATPase
TES1_RS02955	COG0419	ATPase involved in DNA repair
TES1_RS02955	COG0419	ATPase involved in DNA repair
TES1_RS02965	COG0343	queuine tRNA-ribosyltransferase activity
TES1_RS02970	COG0306	phosphate transporter
TES1_RS02975	COG1215	transferase activity, transferring glycosyl groups
TES1_RS02985	COG0470	DNA polymerase III
TES1_RS02985	COG1067	ATP-dependent peptidase activity
TES1_RS03020	COG1694	Mazg nucleotide pyrophosphohydrolase
TES1_RS03025	COG1522	sequence-specific DNA binding
TES1_RS03030	COG1836	PFAM Integral membrane protein DUF92
TES1_RS03035	COG0552	protein localization to endoplasmic reticulum
TES1_RS03040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TES1_RS03045	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TES1_RS03050	COG0352	thiamine-phosphate diphosphorylase activity
TES1_RS03055	COG0351	phosphomethylpyrimidine kinase
TES1_RS03060	COG1121	(ABC) transporter
TES1_RS03070	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TES1_RS03080	COG2890	protein-(glutamine-N5) methyltransferase activity
TES1_RS03110	COG2226	methyltransferase
TES1_RS03145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS03150	COG0644	oxidoreductase
TES1_RS03160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TES1_RS03225	COG1131	(ABC) transporter
TES1_RS03240	COG0084	hydrolase, TatD family'
TES1_RS03250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TES1_RS03255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TES1_RS03275	COG1201	RNA secondary structure unwinding
TES1_RS03285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TES1_RS03300	COG1120	ATPase activity
TES1_RS03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TES1_RS03395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TES1_RS03415	COG1013	pyruvate-flavodoxin oxidoreductase activity
TES1_RS03420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TES1_RS03420	COG0674	pyruvate-flavodoxin oxidoreductase activity
TES1_RS03430	COG1013	pyruvate-flavodoxin oxidoreductase activity
TES1_RS03435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TES1_RS03435	COG0674	pyruvate-flavodoxin oxidoreductase activity
TES1_RS03455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TES1_RS03460	COG2095	MarC family integral membrane protein
TES1_RS03480	COG2205	protein histidine kinase activity
TES1_RS03505	COG1469	GTP cyclohydrolase I activity
TES1_RS03525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TES1_RS03550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TES1_RS03555	COG1850	ribulose-bisphosphate carboxylase activity
TES1_RS03560	COG1435	thymidine kinase activity
TES1_RS03590	COG2379	hydroxypyruvate reductase
TES1_RS03610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TES1_RS03615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TES1_RS03620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TES1_RS03625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TES1_RS03630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TES1_RS03635	COG4821	SIS domain
TES1_RS03665	COG1832	CoA-binding protein
TES1_RS03695	COG1160	GTP binding
TES1_RS03705	COG1418	mRNA catabolic process
TES1_RS03710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TES1_RS03730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TES1_RS03745	COG2414	aldehyde ferredoxin oxidoreductase
TES1_RS03810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TES1_RS03820	COG0438	transferase activity, transferring glycosyl groups
TES1_RS03860	COG0730	response to heat
TES1_RS03865	COG0469	pyruvate kinase activity
TES1_RS03895	COG1110	DNA topoisomerase II activity
TES1_RS03920	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TES1_RS03930	COG0546	phosphoglycolate phosphatase activity
TES1_RS03945	COG1418	mRNA catabolic process
TES1_RS03955	COG0017	Asparaginyl-tRNA synthetase
TES1_RS03970	COG0585	pseudouridine synthase activity
TES1_RS03975	COG0561	phosphatase activity
TES1_RS03990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TES1_RS04035	COG1122	ATPase activity
TES1_RS04040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TES1_RS04045	COG0402	S-adenosylhomocysteine deaminase activity
TES1_RS04050	COG0024	Methionine aminopeptidase
TES1_RS04060	COG2239	Acts as a magnesium transporter
TES1_RS04070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TES1_RS04075	COG1968	undecaprenyl-diphosphatase activity
TES1_RS04080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TES1_RS04090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_RS04115	COG0504	CTP synthase activity
TES1_RS04260	COG0312	modulator of DNA gyrase
TES1_RS04265	COG0312	modulator of DNA gyrase
TES1_RS04270	COG0720	synthase
TES1_RS04300	COG0601	transmembrane transport
TES1_RS04305	COG0730	response to heat
TES1_RS04310	COG0730	response to heat
TES1_RS04315	COG1363	Peptidase, m42
TES1_RS04320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TES1_RS04325	COG0442	prolyl-tRNA aminoacylation
TES1_RS04330	COG2192	nodulation
TES1_RS04335	COG0436	Aminotransferase
TES1_RS04350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TES1_RS04365	COG2226	methyltransferase
TES1_RS04375	COG0525	valine-tRNA ligase activity
TES1_RS04400	COG0864	Transcriptional regulator
TES1_RS04415	COG1881	PFAM PEBP family protein
TES1_RS04445	COG0475	glutathione-regulated potassium exporter activity
TES1_RS04455	COG0822	iron-sulfur transferase activity
TES1_RS04475	COG1151	hydroxylamine reductase activity
TES1_RS04490	COG0006	proline dipeptidase activity
TES1_RS04530	COG0649	NAD binding
TES1_RS04535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS04540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS04545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TES1_RS04550	COG0651	ATP synthesis coupled electron transport
TES1_RS04555	COG0651	ATP synthesis coupled electron transport
TES1_RS04565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TES1_RS04565	COG2111	Na H antiporter
TES1_RS04575	COG1320	monovalent cation:proton antiporter activity
TES1_RS04580	COG2212	antiporter activity
TES1_RS04585	COG1863	multisubunit Na H antiporter MnhE subunit
TES1_RS04600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TES1_RS04615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TES1_RS04640	COG0018	arginyl-trna synthetase
TES1_RS04650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TES1_RS04730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TES1_RS04760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TES1_RS04790	COG0616	signal peptide processing
TES1_RS04800	COG0628	permease
TES1_RS04810	COG1121	(ABC) transporter
TES1_RS04815	COG1111	helicase
TES1_RS04815	COG1205	dead DEAH box helicase
TES1_RS04840	COG0163	prenyltransferase activity
TES1_RS04845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TES1_RS04855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TES1_RS04860	COG0051	transcription antitermination factor activity, RNA binding
TES1_RS04875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TES1_RS04905	COG1131	(ABC) transporter
TES1_RS04915	COG0393	Putative heavy-metal-binding
TES1_RS04920	COG0315	cyclic pyranopterin monophosphate synthase activity
TES1_RS04930	COG1193	negative regulation of DNA recombination
TES1_RS04935	COG0515	serine threonine protein kinase
TES1_RS04965	COG1078	dGTPase activity
TES1_RS05005	COG0501	Belongs to the peptidase M48B family
TES1_RS05010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TES1_RS05020	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TES1_RS05030	COG1515	deoxyribonuclease V activity
TES1_RS05060	COG1476	TRANSCRIPTIONal
TES1_RS05075	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TES1_RS05080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TES1_RS05090	COG1492	cobalamin metabolic process
TES1_RS05095	COG2342	PFAM TM1410 hypothetical-related protein
TES1_RS05105	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TES1_RS05130	COG1573	uracil-dna glycosylase
TES1_RS05145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TES1_RS05160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TES1_RS05165	COG0437	4 iron, 4 sulfur cluster binding
TES1_RS05170	COG0493	'glutamate synthase
TES1_RS05190	COG1201	RNA secondary structure unwinding
TES1_RS05205	COG1505	serine-type exopeptidase activity
TES1_RS05210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TES1_RS05225	COG1047	Peptidyl-prolyl cis-trans
TES1_RS05230	COG0215	cysteine-tRNA ligase activity
TES1_RS05240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TES1_RS05260	COG0803	Belongs to the bacterial solute-binding protein 9 family
TES1_RS05265	COG1079	Belongs to the binding-protein-dependent transport system permease family
TES1_RS05270	COG4603	Belongs to the binding-protein-dependent transport system permease family
TES1_RS05275	COG3845	ABC transporter
TES1_RS05280	COG1744	ABC transporter substrate-binding protein PnrA-like
TES1_RS05290	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TES1_RS05295	COG1518	maintenance of DNA repeat elements
TES1_RS05375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TES1_RS05400	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TES1_RS05415	COG1446	asparaginase
TES1_RS05420	COG2814	Major facilitator Superfamily
TES1_RS05440	COG2271	Major facilitator Superfamily
TES1_RS05445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TES1_RS05455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TES1_RS05470	COG2131	deaminase
TES1_RS05475	COG0501	Belongs to the peptidase M48B family
TES1_RS05485	COG0528	UMP kinase activity
TES1_RS05500	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
TES1_RS05515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TES1_RS05555	COG0733	neurotransmitter:sodium symporter activity
TES1_RS05560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_RS05565	COG1522	sequence-specific DNA binding
TES1_RS05570	COG0693	protein deglycase activity
TES1_RS05595	COG1765	OsmC-like protein
TES1_RS05605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TES1_RS05615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TES1_RS05630	COG4670	ketone body catabolic process
TES1_RS05640	COG0517	IMP dehydrogenase activity
TES1_RS05640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TES1_RS05655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TES1_RS05660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TES1_RS05660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TES1_RS05680	COG0489	protein tyrosine kinase activity
TES1_RS05685	COG0489	protein tyrosine kinase activity
TES1_RS05695	COG1342	Belongs to the UPF0251 family
TES1_RS05740	COG0513	Belongs to the DEAD box helicase family
TES1_RS05760	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TES1_RS05775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TES1_RS05785	COG0330	HflC and HflK could
TES1_RS05800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TES1_RS05840	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TES1_RS05845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TES1_RS05850	COG1984	allophanate hydrolase subunit 2
TES1_RS05860	COG0371	Dehydrogenase
TES1_RS05870	COG0483	inositol monophosphate 1-phosphatase activity
TES1_RS05885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TES1_RS05890	COG1196	nuclear chromosome segregation
TES1_RS05910	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TES1_RS05910	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TES1_RS05915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TES1_RS05920	COG0424	maF-like protein
TES1_RS05930	COG2894	cell division
TES1_RS05940	COG0367	asparagine synthase
TES1_RS05950	COG0438	transferase activity, transferring glycosyl groups
TES1_RS05955	COG0009	L-threonylcarbamoyladenylate synthase
TES1_RS05970	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TES1_RS05975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TES1_RS06000	COG2267	carboxylic ester hydrolase activity
TES1_RS06010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TES1_RS06025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TES1_RS06105	COG0045	succinate-CoA ligase (ADP-forming) activity
TES1_RS06105	COG1042	CoA-binding domain protein
TES1_RS06105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TES1_RS06120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TES1_RS06130	COG0303	'Molybdopterin
TES1_RS06135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TES1_RS06175	COG0105	UTP biosynthetic process
TES1_RS06180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TES1_RS06190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TES1_RS06195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TES1_RS06200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TES1_RS06215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TES1_RS06215	COG1213	nucleotidyl transferase
TES1_RS06225	COG3842	ATPase activity
TES1_RS06230	COG0395	ABC-type sugar transport system, permease component
TES1_RS06275	COG1199	ATP-dependent helicase activity
TES1_RS06295	COG0651	ATP synthesis coupled electron transport
TES1_RS06305	COG1006	Multisubunit Na H antiporter MnhC subunit
TES1_RS06310	COG2111	Na H antiporter
TES1_RS06320	COG1320	monovalent cation:proton antiporter activity
TES1_RS06330	COG3260	NADH ubiquinone oxidoreductase 20
TES1_RS06335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS06340	COG3261	NADH dehydrogenase
TES1_RS06340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TES1_RS06345	COG0650	Formate hydrogenlyase subunit 4
TES1_RS06350	COG0651	ATP synthesis coupled electron transport
TES1_RS06360	COG0003	Pfam Anion-transporting ATPase
TES1_RS06365	COG1151	hydroxylamine reductase activity
TES1_RS06370	COG0437	4 iron, 4 sulfur cluster binding
TES1_RS06385	COG1489	DNA binding
TES1_RS06405	COG3473	Maleate cis-trans isomerase
TES1_RS06410	COG0778	Nitroreductase
TES1_RS06420	COG0301	tRNA thio-modification
TES1_RS06465	COG1042	CoA-binding domain protein
TES1_RS06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TES1_RS06465	COG0045	succinate-CoA ligase (ADP-forming) activity
TES1_RS06485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TES1_RS06500	COG1131	(ABC) transporter
TES1_RS06515	COG0126	phosphoglycerate kinase activity
TES1_RS06540	COG1178	ABC-type Fe3 transport system permease component
TES1_RS06570	COG0513	Belongs to the DEAD box helicase family
TES1_RS06585	COG0017	Asparaginyl-tRNA synthetase
TES1_RS06590	COG0402	S-adenosylhomocysteine deaminase activity
TES1_RS06610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TES1_RS06675	COG1051	belongs to the nudix hydrolase family
TES1_RS06675	COG1056	cytidyltransferase-related domain
TES1_RS06720	COG2226	methyltransferase
TES1_RS06790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TES1_RS06830	COG0588	phosphoglycerate mutase activity
TES1_RS06835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TES1_RS06840	COG0071	Belongs to the small heat shock protein (HSP20) family
TES1_RS06875	COG2119	membrane
TES1_RS06880	COG0436	Aminotransferase
TES1_RS06895	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TES1_RS06900	COG1192	Involved in chromosome partitioning
TES1_RS06910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TES1_RS06910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TES1_RS06925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TES1_RS06925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TES1_RS06930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TES1_RS06930	COG1793	dna ligase
TES1_RS06960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TES1_RS06965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TES1_RS06990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TES1_RS06995	COG0183	Belongs to the thiolase family
TES1_RS07030	COG0123	including yeast histone deacetylase and acetoin utilization protein
TES1_RS07050	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TES1_RS07080	COG0535	radical SAM domain protein
TES1_RS07085	COG2414	aldehyde ferredoxin oxidoreductase
TES1_RS07100	COG1141	Ferredoxin
TES1_RS07105	COG1141	Ferredoxin
TES1_RS07110	COG2151	metal-sulfur cluster biosynthetic enzyme
TES1_RS07130	COG1402	creatininase
TES1_RS07135	COG0438	transferase activity, transferring glycosyl groups
TES1_RS07155	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TES1_RS07160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TES1_RS07205	COG1320	monovalent cation:proton antiporter activity
TES1_RS07210	COG2212	antiporter activity
TES1_RS07215	COG1863	multisubunit Na H antiporter MnhE subunit
TES1_RS07220	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TES1_RS07225	COG0309	Hydrogenase expression formation protein (HypE)
TES1_RS07250	COG0489	protein tyrosine kinase activity
TES1_RS07280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TES1_RS07285	COG2217	Heavy metal translocating P-type atpase
TES1_RS07310	COG0626	cystathionine gamma-synthase activity
TES1_RS07325	COG2217	Heavy metal translocating P-type atpase
TES1_RS07335	COG2217	Heavy metal translocating P-type atpase
TES1_RS07375	COG0396	ATPase activity
TES1_RS07380	COG0301	tRNA thio-modification
TES1_RS07385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TES1_RS07390	COG1528	Iron-storage protein
TES1_RS07405	COG0432	Pfam Uncharacterised protein family UPF0047
TES1_RS07415	COG1992	Thiamine-phosphate synthase
TES1_RS07415	COG0351	phosphomethylpyrimidine kinase
TES1_RS07435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TES1_RS07475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TES1_RS07480	COG0434	BtpA family
TES1_RS07530	COG0312	modulator of DNA gyrase
TES1_RS07535	COG0312	modulator of DNA gyrase
TES1_RS07555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TES1_RS07600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS07605	COG0650	Formate hydrogenlyase subunit 4
TES1_RS07615	COG0649	NAD binding
TES1_RS07615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS07620	COG3260	NADH ubiquinone oxidoreductase 20
TES1_RS07630	COG0651	ATP synthesis coupled electron transport
TES1_RS07635	COG1006	Multisubunit Na H antiporter MnhC subunit
TES1_RS07655	COG1320	monovalent cation:proton antiporter activity
TES1_RS07660	COG2212	antiporter activity
TES1_RS07675	COG0650	Formate hydrogenlyase subunit 4
TES1_RS07685	COG3261	NADH dehydrogenase
TES1_RS07685	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TES1_RS07690	COG3260	NADH ubiquinone oxidoreductase 20
TES1_RS07700	COG0651	ATP synthesis coupled electron transport
TES1_RS07705	COG1006	Multisubunit Na H antiporter MnhC subunit
TES1_RS07725	COG1320	monovalent cation:proton antiporter activity
TES1_RS07730	COG2212	antiporter activity
TES1_RS07735	COG1863	multisubunit Na H antiporter MnhE subunit
TES1_RS07740	COG0651	ATP synthesis coupled electron transport
TES1_RS07750	COG1006	Multisubunit Na H antiporter MnhC subunit
TES1_RS07755	COG2111	Na H antiporter
TES1_RS07765	COG1320	monovalent cation:proton antiporter activity
TES1_RS07775	COG2116	formate transmembrane transporter activity
TES1_RS07785	COG3260	NADH ubiquinone oxidoreductase 20
TES1_RS07790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS07795	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TES1_RS07795	COG3261	NADH dehydrogenase
TES1_RS07800	COG0650	Formate hydrogenlyase subunit 4
TES1_RS07805	COG0651	ATP synthesis coupled electron transport
TES1_RS07810	COG0651	ATP synthesis coupled electron transport
TES1_RS07815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TES1_RS07820	COG0437	4 iron, 4 sulfur cluster binding
TES1_RS07825	COG3383	formate dehydrogenase (NAD+) activity
TES1_RS07830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TES1_RS07845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TES1_RS07850	COG3259	Nickel-dependent hydrogenase
TES1_RS07860	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TES1_RS07865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TES1_RS07885	COG1476	TRANSCRIPTIONal
TES1_RS07895	COG1131	(ABC) transporter
TES1_RS07955	COG0543	2 iron, 2 sulfur cluster binding
TES1_RS07960	COG0493	'glutamate synthase
TES1_RS07960	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TES1_RS07970	COG0509	glycine decarboxylation via glycine cleavage system
TES1_RS07985	COG1254	Belongs to the acylphosphatase family
TES1_RS07995	COG1628	Protein of unknown function DUF99
TES1_RS08000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TES1_RS08015	COG2255	four-way junction helicase activity
TES1_RS08025	COG0492	ferredoxin-NADP+ reductase activity
TES1_RS08030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TES1_RS08040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TES1_RS08055	COG0148	phosphopyruvate hydratase activity
TES1_RS08060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TES1_RS08075	COG1131	(ABC) transporter
TES1_RS08100	COG0489	protein tyrosine kinase activity
TES1_RS08105	COG1013	pyruvate-flavodoxin oxidoreductase activity
TES1_RS08110	COG0674	pyruvate-flavodoxin oxidoreductase activity
TES1_RS08120	COG1013	pyruvate-flavodoxin oxidoreductase activity
TES1_RS08125	COG0674	pyruvate-flavodoxin oxidoreductase activity
TES1_RS08130	COG1144	Oxidoreductase
TES1_RS08145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TES1_RS08155	COG0475	glutathione-regulated potassium exporter activity
TES1_RS08175	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TES1_RS08185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TES1_RS08195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TES1_RS08210	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TES1_RS08210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TES1_RS08235	COG0589	response to stress
TES1_RS08240	COG1136	(ABC) transporter
TES1_RS08250	COG0577	efflux transmembrane transporter activity
TES1_RS08250	COG1136	(ABC) transporter
TES1_RS08255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TES1_RS08290	COG1451	nucleotide metabolic process
TES1_RS08365	COG0395	ABC-type sugar transport system, permease component
TES1_RS08370	COG1175	transmembrane transport
TES1_RS08400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TES1_RS08405	COG4608	Belongs to the ABC transporter superfamily
TES1_RS08410	COG0444	Belongs to the ABC transporter superfamily
TES1_RS08415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TES1_RS08420	COG0601	transmembrane transport
TES1_RS08425	COG0747	negative chemotaxis
TES1_RS08445	COG0281	malic enzyme
TES1_RS08450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TES1_RS08480	COG2252	PERMEase
TES1_RS08495	COG0235	Class ii aldolase
TES1_RS08535	COG0011	TIGRFAM Protein of
TES1_RS08540	COG2078	PFAM AMMECR1 domain protein
TES1_RS08545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TES1_RS08545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TES1_RS08550	COG0417	DNA replication proofreading
TES1_RS08605	COG1695	Transcriptional regulator
TES1_RS08610	COG2050	protein possibly involved in aromatic compounds catabolism
TES1_RS08610	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TES1_RS08625	COG1335	isochorismatase
TES1_RS08665	COG0442	prolyl-tRNA aminoacylation
TES1_RS08680	COG0297	glycogen (starch) synthase activity
TES1_RS08685	COG1378	Sugar-specific transcriptional regulator TrmB
TES1_RS08695	COG2182	Extracellular solute-binding protein
TES1_RS08700	COG1175	transmembrane transport
TES1_RS08705	COG3833	ABC-type maltose transport systems, permease component
TES1_RS08715	COG3842	ATPase activity
TES1_RS08725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TES1_RS08730	COG1234	tRNA 3'-trailer cleavage
TES1_RS08735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TES1_RS08745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TES1_RS08770	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TES1_RS08785	COG0697	spore germination
TES1_RS08810	COG0174	glutamine synthetase
TES1_RS08830	COG4608	Belongs to the ABC transporter superfamily
TES1_RS08835	COG0444	Belongs to the ABC transporter superfamily
TES1_RS08840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TES1_RS08845	COG0601	transmembrane transport
TES1_RS08870	COG0519	Catalyzes the synthesis of GMP from XMP
TES1_RS08870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TES1_RS08875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TES1_RS08880	COG1394	ATPase activity, coupled to movement of substances
TES1_RS08890	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TES1_RS08905	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TES1_RS08915	COG1269	ATP hydrolysis coupled proton transport
TES1_RS08925	COG0569	domain protein
TES1_RS08930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TES1_RS08940	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TES1_RS08950	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TES1_RS08975	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TES1_RS08985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TES1_RS08990	COG1115	amino acid carrier protein
TES1_RS09010	COG0124	histidyl-tRNA synthetase
TES1_RS09020	COG2264	protein methyltransferase activity
TES1_RS09080	COG2234	aminopeptidase activity
TES1_RS09085	COG0463	Glycosyl transferase, family 2
TES1_RS09105	COG4143	(ABC) transporter
TES1_RS09125	COG1444	tRNA N-acetyltransferase activity
TES1_RS09130	COG1506	peptidase
TES1_RS09130	COG0823	Involved in the tonB-independent uptake of proteins
TES1_RS09130	COG4946	Tricorn protease homolog
TES1_RS09135	COG1196	nuclear chromosome segregation
TES1_RS09160	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
TES1_RS09170	COG1268	BioY protein
TES1_RS09175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TES1_RS09175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TES1_RS09185	COG1122	ATPase activity
TES1_RS09190	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TES1_RS09210	COG1111	helicase
TES1_RS09210	COG1205	dead DEAH box helicase
TES1_RS09220	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TES1_RS09240	COG0306	phosphate transporter
TES1_RS09265	COG1506	peptidase
TES1_RS09265	COG0823	Involved in the tonB-independent uptake of proteins
TES1_RS09265	COG4946	Tricorn protease homolog
TES1_RS09285	COG0681	Belongs to the peptidase S26 family
TES1_RS09290	COG0095	Lipoate-protein ligase
TES1_RS09335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TES1_RS09370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TES1_RS09380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TES1_RS09435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TES1_RS09445	COG0501	Belongs to the peptidase M48B family
TES1_RS09475	COG0314	molybdopterin synthase activity
TES1_RS09495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TES1_RS09500	COG1522	sequence-specific DNA binding
TES1_RS09515	COG1980	fructose-bisphosphate aldolase activity
TES1_RS09535	COG3842	ATPase activity
TES1_RS09560	COG0673	inositol 2-dehydrogenase activity
TES1_RS09565	COG0463	Glycosyl transferase, family 2
TES1_RS09605	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TES1_RS09620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TES1_RS09625	COG0402	S-adenosylhomocysteine deaminase activity
TES1_RS09630	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TES1_RS09630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TES1_RS09635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TES1_RS09635	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TES1_RS09650	COG0640	Transcriptional regulator
TES1_RS09655	COG0471	metal ion transport
TES1_RS09655	COG0490	domain, Protein
TES1_RS09675	COG0179	Fumarylacetoacetate (FAA) hydrolase
TES1_RS09685	COG0116	Belongs to the methyltransferase superfamily
TES1_RS09685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TES1_RS09690	COG1160	GTP binding
TES1_RS09725	COG1047	Peptidyl-prolyl cis-trans
TES1_RS09750	COG0714	Associated with various cellular activities
TES1_RS09770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TES1_RS09790	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TES1_RS09835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TES1_RS09855	COG1442	glycosyl transferase family 8
TES1_RS09855	COG1216	Glycosyl transferase, family 2
TES1_RS09895	COG4651	solute:proton antiporter activity
TES1_RS09895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TES1_RS09925	COG1449	Belongs to the glycosyl hydrolase 57 family
TES1_RS09935	COG0037	tRNA processing
TES1_RS09945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TES1_RS09955	COG0475	glutathione-regulated potassium exporter activity
TES1_RS09960	COG0475	glutathione-regulated potassium exporter activity
TES1_RS09970	COG1522	sequence-specific DNA binding
TES1_RS09985	COG1793	dna ligase
TES1_RS10000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TES1_RS10010	COG1757	Na H antiporter
TES1_RS10015	COG1573	uracil-dna glycosylase
TES1_RS10025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TES1_RS10045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TES1_RS10060	COG0395	ABC-type sugar transport system, permease component
TES1_RS10065	COG1175	transmembrane transport
TES1_RS10075	COG0438	transferase activity, transferring glycosyl groups
TES1_RS10090	COG1380	Effector of murein hydrolase LrgA
TES1_RS10095	COG1346	cytolysis
TES1_RS10120	COG0668	transmembrane transport
TES1_RS10230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TES1_RS10245	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TES1_RS10280	COG0539	negative regulation of cytoplasmic translation
TES1_RS10310	COG2890	protein-(glutamine-N5) methyltransferase activity
TES1_RS10370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TES1_RS10370	COG0519	Catalyzes the synthesis of GMP from XMP
TES1_RS10375	COG0519	Catalyzes the synthesis of GMP from XMP
TES1_RS10375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TES1_RS10380	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
TES1_RS10390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TES1_RS10400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TES1_RS10405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TES1_RS10405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TES1_RS10410	COG0307	riboflavin synthase, alpha
TES1_RS10415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TES1_RS10415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TES1_RS10420	COG0516	GMP reductase activity
TES1_RS10420	COG0517	IMP dehydrogenase activity
TES1_RS10440	COG1328	CTP reductase activity
TES1_RS10450	COG1785	Belongs to the alkaline phosphatase family
TES1_RS10465	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
TES1_RS10505	COG2046	Belongs to the sulfate adenylyltransferase family
TES1_RS10530	COG0529	Catalyzes the synthesis of activated sulfate
TES1_RS10535	COG0730	response to heat
TES1_RS10615	COG1368	sulfuric ester hydrolase activity
TES1_RS10640	COG0438	transferase activity, transferring glycosyl groups
TES1_RS10650	COG0438	transferase activity, transferring glycosyl groups
TES1_RS10650	COG0297	glycogen (starch) synthase activity
TES1_RS10660	COG1216	Glycosyl transferase, family 2
TES1_RS10665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TES1_RS10700	COG1309	transcriptional regulator
TES1_RS10735	COG0454	-acetyltransferase
TES1_RS10785	COG2813	Specifically methylates the guanine in position
TES1_RS10845	COG2835	tetraacyldisaccharide 4'-kinase activity