locus-tag	class	description
A7C91_RS00010	COG1353	crispr-associated protein
A7C91_RS00020	COG1337	RAMP superfamily
A7C91_RS00040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_RS00050	COG1301	dicarboxylic acid transport
A7C91_RS00060	COG1830	Aldolase
A7C91_RS00095	COG2267	carboxylic ester hydrolase activity
A7C91_RS00115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7C91_RS00130	COG0455	bacterial-type flagellum organization
A7C91_RS00135	COG0489	protein tyrosine kinase activity
A7C91_RS00200	COG1342	Belongs to the UPF0251 family
A7C91_RS00205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7C91_RS00230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_RS00275	COG1201	RNA secondary structure unwinding
A7C91_RS00280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7C91_RS00285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7C91_RS00295	COG0084	hydrolase, TatD family'
A7C91_RS00330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7C91_RS00340	COG0105	UTP biosynthetic process
A7C91_RS00385	COG0175	sulfate reduction
A7C91_RS00400	COG0402	S-adenosylhomocysteine deaminase activity
A7C91_RS00405	COG0017	Asparaginyl-tRNA synthetase
A7C91_RS00420	COG4143	(ABC) transporter
A7C91_RS00440	COG1444	tRNA N-acetyltransferase activity
A7C91_RS00455	COG1268	BioY protein
A7C91_RS00460	COG1122	ATPase activity
A7C91_RS00465	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7C91_RS00490	COG1522	sequence-specific DNA binding
A7C91_RS00510	COG1178	ABC-type Fe3 transport system permease component
A7C91_RS00515	COG3842	ATPase activity
A7C91_RS00540	COG0126	phosphoglycerate kinase activity
A7C91_RS00565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7C91_RS00595	COG1042	CoA-binding domain protein
A7C91_RS00595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_RS00595	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_RS00605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7C91_RS00625	COG0301	tRNA thio-modification
A7C91_RS00640	COG3473	Maleate cis-trans isomerase
A7C91_RS00660	COG1489	DNA binding
A7C91_RS00680	COG1199	ATP-dependent helicase activity
A7C91_RS00695	COG0513	Belongs to the DEAD box helicase family
A7C91_RS00725	COG1979	alcohol dehydrogenase
A7C91_RS00735	COG1984	allophanate hydrolase subunit 2
A7C91_RS00740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7C91_RS00745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7C91_RS00780	COG0330	HflC and HflK could
A7C91_RS00800	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7C91_RS00815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A7C91_RS00865	COG1196	nuclear chromosome segregation
A7C91_RS00875	COG0346	lactoylglutathione lyase activity
A7C91_RS00885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_RS00885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_RS00890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7C91_RS00895	COG0424	maF-like protein
A7C91_RS00900	COG4956	integral membrane protein (PIN domain superfamily)
A7C91_RS00905	COG2894	cell division
A7C91_RS00915	COG0367	asparagine synthase
A7C91_RS00925	COG0297	glycogen (starch) synthase activity
A7C91_RS00930	COG0009	L-threonylcarbamoyladenylate synthase
A7C91_RS00950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7C91_RS00955	COG0303	'Molybdopterin
A7C91_RS00965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_RS00980	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_RS00980	COG1042	CoA-binding domain protein
A7C91_RS00980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_RS01020	COG0482	sulfurtransferase activity
A7C91_RS01055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_RS01055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_RS01075	COG0071	Belongs to the small heat shock protein (HSP20) family
A7C91_RS01235	COG0560	Phosphoserine phosphatase
A7C91_RS01255	COG0535	radical SAM domain protein
A7C91_RS01260	COG1056	cytidyltransferase-related domain
A7C91_RS01260	COG1051	belongs to the nudix hydrolase family
A7C91_RS01280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7C91_RS01310	COG0560	Phosphoserine phosphatase
A7C91_RS01315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7C91_RS01380	COG2264	protein methyltransferase activity
A7C91_RS01400	COG0835	chemotaxis
A7C91_RS01405	COG0840	transmembrane signaling receptor activity
A7C91_RS01415	COG2201	protein-glutamate methylesterase activity
A7C91_RS01420	COG2201	protein-glutamate methylesterase activity
A7C91_RS01425	COG2198	Histidine kinase
A7C91_RS01425	COG0643	Histidine kinase
A7C91_RS01440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A7C91_RS01445	COG0840	transmembrane signaling receptor activity
A7C91_RS01495	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A7C91_RS01500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A7C91_RS01520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A7C91_RS01525	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7C91_RS01540	COG1160	GTP binding
A7C91_RS01545	COG0432	Pfam Uncharacterised protein family UPF0047
A7C91_RS01610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7C91_RS01615	COG1435	thymidine kinase activity
A7C91_RS01665	COG4555	ABC transporter
A7C91_RS01700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A7C91_RS01700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7C91_RS01710	COG1192	Involved in chromosome partitioning
A7C91_RS01715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7C91_RS01730	COG0436	Aminotransferase
A7C91_RS01735	COG2119	membrane
A7C91_RS01770	COG1404	Belongs to the peptidase S8 family
A7C91_RS01900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A7C91_RS01905	COG0167	dihydroorotate dehydrogenase activity
A7C91_RS01930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7C91_RS01940	COG0528	UMP kinase activity
A7C91_RS01950	COG0535	radical SAM domain protein
A7C91_RS01985	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_RS01995	COG0501	Belongs to the peptidase M48B family
A7C91_RS02015	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_RS02020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7C91_RS02035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_RS02040	COG1522	sequence-specific DNA binding
A7C91_RS02045	COG0693	protein deglycase activity
A7C91_RS02080	COG1765	OsmC-like protein
A7C91_RS02090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A7C91_RS02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7C91_RS02100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_RS02125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7C91_RS02170	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7C91_RS02190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7C91_RS02230	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A7C91_RS02250	COG0651	ATP synthesis coupled electron transport
A7C91_RS02275	COG1320	monovalent cation:proton antiporter activity
A7C91_RS02280	COG2212	antiporter activity
A7C91_RS02285	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_RS02310	COG0493	'glutamate synthase
A7C91_RS02315	COG0543	2 iron, 2 sulfur cluster binding
A7C91_RS02355	COG0563	adenylate kinase activity
A7C91_RS02360	COG0428	transporter
A7C91_RS02375	COG1131	(ABC) transporter
A7C91_RS02385	COG1476	TRANSCRIPTIONal
A7C91_RS02425	COG0543	2 iron, 2 sulfur cluster binding
A7C91_RS02430	COG0493	'glutamate synthase
A7C91_RS02450	COG1141	Ferredoxin
A7C91_RS02460	COG2151	metal-sulfur cluster biosynthetic enzyme
A7C91_RS02485	COG1404	Belongs to the peptidase S8 family
A7C91_RS02495	COG0535	radical SAM domain protein
A7C91_RS02510	COG0501	Belongs to the peptidase M48B family
A7C91_RS02515	COG2131	deaminase
A7C91_RS02530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7C91_RS02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_RS02545	COG2271	Major facilitator Superfamily
A7C91_RS02565	COG2814	Major facilitator Superfamily
A7C91_RS02570	COG1446	asparaginase
A7C91_RS02590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A7C91_RS02630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A7C91_RS02645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7C91_RS02655	COG1530	ribonuclease E activity
A7C91_RS02665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7C91_RS02680	COG2255	four-way junction helicase activity
A7C91_RS02685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7C91_RS02690	COG0156	8-amino-7-oxononanoate synthase activity
A7C91_RS02705	COG1214	PFAM Peptidase M22, glycoprotease
A7C91_RS02705	COG0456	acetyltransferase
A7C91_RS02710	COG0433	COG0433 Predicted ATPase
A7C91_RS02720	COG0419	ATPase involved in DNA repair
A7C91_RS02720	COG0419	ATPase involved in DNA repair
A7C91_RS02735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7C91_RS02740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A7C91_RS02745	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_RS02760	COG3885	ferrous iron binding
A7C91_RS02760	COG2078	PFAM AMMECR1 domain protein
A7C91_RS02795	COG0351	phosphomethylpyrimidine kinase
A7C91_RS02795	COG1992	Thiamine-phosphate synthase
A7C91_RS02800	COG0540	Belongs to the ATCase OTCase family
A7C91_RS02805	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A7C91_RS02855	COG1091	dTDP-4-dehydrorhamnose reductase activity
A7C91_RS02895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7C91_RS02925	COG0714	Associated with various cellular activities
A7C91_RS02965	COG0647	UMP catabolic process
A7C91_RS02975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7C91_RS03015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7C91_RS03045	COG2414	aldehyde ferredoxin oxidoreductase
A7C91_RS03055	COG0697	spore germination
A7C91_RS03095	COG1378	Sugar-specific transcriptional regulator TrmB
A7C91_RS03130	COG1234	tRNA 3'-trailer cleavage
A7C91_RS03135	COG1297	OPT oligopeptide transporter protein
A7C91_RS03145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7C91_RS03190	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_RS03230	COG0174	glutamine synthetase
A7C91_RS03250	COG4608	Belongs to the ABC transporter superfamily
A7C91_RS03255	COG0444	Belongs to the ABC transporter superfamily
A7C91_RS03260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7C91_RS03265	COG0601	transmembrane transport
A7C91_RS03295	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A7C91_RS03300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_RS03310	COG0426	domain, Protein
A7C91_RS03310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7C91_RS03325	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A7C91_RS03350	COG1269	ATP hydrolysis coupled proton transport
A7C91_RS03360	COG0569	domain protein
A7C91_RS03365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7C91_RS03370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7C91_RS03375	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A7C91_RS03385	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_RS03415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7C91_RS03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_RS03445	COG0124	histidyl-tRNA synthetase
A7C91_RS03470	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A7C91_RS03480	COG0037	tRNA processing
A7C91_RS03535	COG2046	Belongs to the sulfate adenylyltransferase family
A7C91_RS03550	COG0529	Catalyzes the synthesis of activated sulfate
A7C91_RS03570	COG0367	asparagine synthase
A7C91_RS03575	COG0297	glycogen (starch) synthase activity
A7C91_RS03580	COG1216	Glycosyl transferase, family 2
A7C91_RS03580	COG1442	glycosyl transferase family 8
A7C91_RS03605	COG0673	inositol 2-dehydrogenase activity
A7C91_RS03610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7C91_RS03625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7C91_RS03630	COG0037	tRNA processing
A7C91_RS03650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A7C91_RS03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7C91_RS03680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A7C91_RS03700	COG0714	Associated with various cellular activities
A7C91_RS03725	COG1047	Peptidyl-prolyl cis-trans
A7C91_RS03765	COG0116	Belongs to the methyltransferase superfamily
A7C91_RS03780	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7C91_RS03795	COG0180	Tryptophanyl-tRNA synthetase
A7C91_RS03805	COG0471	metal ion transport
A7C91_RS03805	COG0490	domain, Protein
A7C91_RS03810	COG0640	Transcriptional regulator
A7C91_RS03855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_RS03855	COG0731	radical SAM domain protein
A7C91_RS03875	COG0402	S-adenosylhomocysteine deaminase activity
A7C91_RS03890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7C91_RS03915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7C91_RS03980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7C91_RS03990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7C91_RS04000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_RS04000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_RS04050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7C91_RS04060	COG0314	molybdopterin synthase activity
A7C91_RS04080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7C91_RS04085	COG1522	sequence-specific DNA binding
A7C91_RS04095	COG0148	phosphopyruvate hydratase activity
A7C91_RS04110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A7C91_RS04125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7C91_RS04130	COG0492	ferredoxin-NADP+ reductase activity
A7C91_RS04150	COG2255	four-way junction helicase activity
A7C91_RS04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7C91_RS04155	COG0301	tRNA thio-modification
A7C91_RS04170	COG0650	Formate hydrogenlyase subunit 4
A7C91_RS04180	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A7C91_RS04180	COG3261	NADH dehydrogenase
A7C91_RS04185	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_RS04195	COG0651	ATP synthesis coupled electron transport
A7C91_RS04200	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_RS04220	COG1320	monovalent cation:proton antiporter activity
A7C91_RS04225	COG2212	antiporter activity
A7C91_RS04230	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_RS04235	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_RS04240	COG0651	ATP synthesis coupled electron transport
A7C91_RS04250	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_RS04255	COG2111	Na H antiporter
A7C91_RS04265	COG1320	monovalent cation:proton antiporter activity
A7C91_RS04275	COG2116	formate transmembrane transporter activity
A7C91_RS04285	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_RS04290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_RS04305	COG0651	ATP synthesis coupled electron transport
A7C91_RS04310	COG0651	ATP synthesis coupled electron transport
A7C91_RS04315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_RS04320	COG3383	formate dehydrogenase (NAD+) activity
A7C91_RS04325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7C91_RS04340	COG3259	Nickel-dependent hydrogenase
A7C91_RS04350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7C91_RS04375	COG0306	phosphate transporter
A7C91_RS04400	COG0823	Involved in the tonB-independent uptake of proteins
A7C91_RS04400	COG1506	peptidase
A7C91_RS04400	COG4946	Tricorn protease homolog
A7C91_RS04440	COG0681	Belongs to the peptidase S26 family
A7C91_RS04445	COG0095	Lipoate-protein ligase
A7C91_RS04490	COG0704	Plays a role in the regulation of phosphate uptake
A7C91_RS04495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7C91_RS04545	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A7C91_RS04585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A7C91_RS04620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7C91_RS04630	COG1573	uracil-dna glycosylase
A7C91_RS04635	COG1757	Na H antiporter
A7C91_RS04645	COG1793	dna ligase
A7C91_RS04655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7C91_RS04665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_RS04670	COG1522	sequence-specific DNA binding
A7C91_RS04755	COG1233	COG1233 Phytoene dehydrogenase and related
A7C91_RS04785	COG1980	fructose-bisphosphate aldolase activity
A7C91_RS04810	COG0589	response to stress
A7C91_RS04815	COG1628	Protein of unknown function DUF99
A7C91_RS04825	COG1254	Belongs to the acylphosphatase family
A7C91_RS04835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7C91_RS04860	COG0489	protein tyrosine kinase activity
A7C91_RS04870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7C91_RS04880	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS04885	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS04895	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS04900	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS04915	COG0306	phosphate transporter
A7C91_RS04920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7C91_RS04935	COG0475	glutathione-regulated potassium exporter activity
A7C91_RS04960	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A7C91_RS04965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7C91_RS04975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7C91_RS05020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_RS05040	COG0312	modulator of DNA gyrase
A7C91_RS05065	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A7C91_RS05070	COG0714	Associated with various cellular activities
A7C91_RS05085	COG0434	BtpA family
A7C91_RS05105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7C91_RS05150	COG2244	polysaccharide biosynthetic process
A7C91_RS05155	COG3119	arylsulfatase activity
A7C91_RS05195	COG1216	Glycosyl transferase, family 2
A7C91_RS05255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7C91_RS05260	COG1120	ATPase activity
A7C91_RS05270	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
A7C91_RS05305	COG0516	GMP reductase activity
A7C91_RS05305	COG0517	IMP dehydrogenase activity
A7C91_RS05340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7C91_RS05350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A7C91_RS05360	COG0157	Belongs to the NadC ModD family
A7C91_RS05380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7C91_RS05390	COG4637	Psort location Cytoplasmic, score
A7C91_RS05425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A7C91_RS05430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7C91_RS05435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7C91_RS05440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7C91_RS05445	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A7C91_RS05450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7C91_RS05455	COG0151	Belongs to the GarS family
A7C91_RS05470	COG0047	phosphoribosylformylglycinamidine synthase activity
A7C91_RS05475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7C91_RS05485	COG0519	Catalyzes the synthesis of GMP from XMP
A7C91_RS05485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7C91_RS05490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7C91_RS05490	COG0519	Catalyzes the synthesis of GMP from XMP
A7C91_RS05550	COG2890	protein-(glutamine-N5) methyltransferase activity
A7C91_RS05580	COG0557	exoribonuclease II activity
A7C91_RS05645	COG2234	aminopeptidase activity
A7C91_RS05665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7C91_RS05690	COG1695	Transcriptional regulator
A7C91_RS05705	COG0393	Putative heavy-metal-binding
A7C91_RS05715	COG2264	protein methyltransferase activity
A7C91_RS05735	COG0668	transmembrane transport
A7C91_RS05785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A7C91_RS05790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7C91_RS05800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A7C91_RS05865	COG2252	PERMEase
A7C91_RS05875	COG4208	sulfate ABC transporter
A7C91_RS05900	COG0011	TIGRFAM Protein of
A7C91_RS05905	COG2078	PFAM AMMECR1 domain protein
A7C91_RS05910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_RS05910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_RS05955	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_RS05975	COG1695	Transcriptional regulator
A7C91_RS05980	COG2050	protein possibly involved in aromatic compounds catabolism
A7C91_RS05980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_RS05990	COG1335	isochorismatase
A7C91_RS05995	COG0628	permease
A7C91_RS06015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_RS06075	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_RS06090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7C91_RS06095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7C91_RS06120	COG2239	Acts as a magnesium transporter
A7C91_RS06125	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A7C91_RS06130	COG5016	pyruvate
A7C91_RS06130	COG0511	ligase activity, forming carbon-carbon bonds
A7C91_RS06140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7C91_RS06150	COG1372	Participates in initiation and elongation during chromosome replication
A7C91_RS06150	COG0305	Participates in initiation and elongation during chromosome replication
A7C91_RS06170	COG0430	RNA-3'-phosphate cyclase activity
A7C91_RS06195	COG0543	2 iron, 2 sulfur cluster binding
A7C91_RS06205	COG0543	2 iron, 2 sulfur cluster binding
A7C91_RS06215	COG0017	Asparaginyl-tRNA synthetase
A7C91_RS06230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7C91_RS06260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A7C91_RS06265	COG0088	Forms part of the polypeptide exit tunnel
A7C91_RS06270	COG0089	rRNA binding
A7C91_RS06275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7C91_RS06280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A7C91_RS06285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7C91_RS06290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A7C91_RS06295	COG0255	Belongs to the universal ribosomal protein uL29 family
A7C91_RS06310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7C91_RS06315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A7C91_RS06330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7C91_RS06340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A7C91_RS06345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7C91_RS06360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7C91_RS06365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A7C91_RS06370	COG1841	ribosomal large subunit assembly
A7C91_RS06375	COG0200	Binds to the 23S rRNA
A7C91_RS06400	COG1102	Psort location Cytoplasmic, score
A7C91_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
A7C91_RS06415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7C91_RS06430	COG2813	Specifically methylates the guanine in position
A7C91_RS06440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7C91_RS06445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7C91_RS06455	COG0202	RNA polymerase activity
A7C91_RS06470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A7C91_RS06475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A7C91_RS06495	COG0148	phosphopyruvate hydratase activity
A7C91_RS06500	COG0052	Belongs to the universal ribosomal protein uS2 family
A7C91_RS06540	COG1522	sequence-specific DNA binding
A7C91_RS06550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7C91_RS06565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7C91_RS06585	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7C91_RS06590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7C91_RS06615	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A7C91_RS06625	COG1355	regulation of microtubule-based process
A7C91_RS06640	COG1304	FMN binding
A7C91_RS06645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7C91_RS06675	COG0495	leucyl-tRNA aminoacylation
A7C91_RS06680	COG2409	Drug exporters of the RND superfamily
A7C91_RS06710	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A7C91_RS06725	COG0864	Transcriptional regulator
A7C91_RS06735	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A7C91_RS06745	COG0347	Belongs to the P(II) protein family
A7C91_RS06755	COG0733	neurotransmitter:sodium symporter activity
A7C91_RS06760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7C91_RS06770	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_RS06775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A7C91_RS06790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A7C91_RS06815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A7C91_RS06820	COG0534	Mate efflux family protein
A7C91_RS06825	COG0574	Belongs to the PEP-utilizing enzyme family
A7C91_RS06825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7C91_RS06865	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_RS06900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7C91_RS06910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7C91_RS06925	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A7C91_RS06930	COG0409	Hydrogenase expression formation protein
A7C91_RS06935	COG0298	carbon dioxide binding
A7C91_RS06940	COG1309	transcriptional regulator
A7C91_RS06945	COG3383	formate dehydrogenase (NAD+) activity
A7C91_RS06955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_RS06960	COG0651	ATP synthesis coupled electron transport
A7C91_RS06965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7C91_RS06970	COG3261	NADH dehydrogenase
A7C91_RS06970	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A7C91_RS06975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_RS06980	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_RS06995	COG1320	monovalent cation:proton antiporter activity
A7C91_RS07010	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_RS07020	COG0651	ATP synthesis coupled electron transport
A7C91_RS07030	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_RS07040	COG0489	protein tyrosine kinase activity
A7C91_RS07070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7C91_RS07075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7C91_RS07080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A7C91_RS07090	COG1234	tRNA 3'-trailer cleavage
A7C91_RS07105	COG1994	Peptidase M50
A7C91_RS07110	COG2140	Oxalate decarboxylase
A7C91_RS07145	COG1122	ATPase activity
A7C91_RS07160	COG0310	cobalt ion transport
A7C91_RS07175	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_RS07205	COG0436	Aminotransferase
A7C91_RS07235	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A7C91_RS07255	COG0049	tRNA binding
A7C91_RS07275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7C91_RS07280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7C91_RS07285	COG0085	RNA polymerase activity
A7C91_RS07315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7C91_RS07365	COG0579	oxidoreductase
A7C91_RS07375	COG0584	glycerophosphoryl diester phosphodiesterase
A7C91_RS07380	COG0584	glycerophosphoryl diester phosphodiesterase
A7C91_RS07385	COG2211	Major facilitator Superfamily
A7C91_RS07390	COG2271	Major facilitator Superfamily
A7C91_RS07395	COG1073	alpha beta
A7C91_RS07400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7C91_RS07415	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A7C91_RS07430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7C91_RS07480	COG0081	regulation of translation
A7C91_RS07485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7C91_RS07500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7C91_RS07535	COG1458	PINc domain ribonuclease
A7C91_RS07550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7C91_RS07555	COG0644	oxidoreductase
A7C91_RS07575	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A7C91_RS07585	COG1518	maintenance of DNA repeat elements
A7C91_RS07595	COG2002	toxin-antitoxin pair type II binding
A7C91_RS07605	COG1203	CRISPR-associated helicase, Cas3
A7C91_RS07650	COG1110	DNA topoisomerase II activity
A7C91_RS07685	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A7C91_RS07695	COG0546	phosphoglycolate phosphatase activity
A7C91_RS07710	COG1418	mRNA catabolic process
A7C91_RS07720	COG0017	Asparaginyl-tRNA synthetase
A7C91_RS07735	COG0585	pseudouridine synthase activity
A7C91_RS07750	COG1473	amidohydrolase
A7C91_RS07775	COG0504	CTP synthase activity
A7C91_RS07795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_RS07805	COG1968	undecaprenyl-diphosphatase activity
A7C91_RS07820	COG0516	GMP reductase activity
A7C91_RS07820	COG0517	IMP dehydrogenase activity
A7C91_RS07835	COG0024	Methionine aminopeptidase
A7C91_RS07840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7C91_RS07845	COG1122	ATPase activity
A7C91_RS07885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7C91_RS07900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7C91_RS07905	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_RS07945	COG0628	permease
A7C91_RS07950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7C91_RS07970	COG1131	(ABC) transporter
A7C91_RS07980	COG0556	nucleotide-excision repair
A7C91_RS07985	COG0101	tRNA pseudouridine synthase activity
A7C91_RS08000	COG1063	alcohol dehydrogenase
A7C91_RS08005	COG2894	cell division
A7C91_RS08020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7C91_RS08025	COG0252	asparaginase activity
A7C91_RS08055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A7C91_RS08065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7C91_RS08090	COG0726	polysaccharide deacetylase
A7C91_RS08105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A7C91_RS08120	COG0038	chloride channel
A7C91_RS08140	COG0010	Belongs to the arginase family
A7C91_RS08190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7C91_RS08200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A7C91_RS08225	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A7C91_RS08230	COG0656	L-ascorbic acid biosynthetic process
A7C91_RS08250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7C91_RS08250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7C91_RS08275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7C91_RS08275	COG0359	binds to the 23S rRNA
A7C91_RS08325	COG0602	queuosine metabolic process
A7C91_RS08340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_RS08410	COG1151	hydroxylamine reductase activity
A7C91_RS08455	COG0649	NAD binding
A7C91_RS08460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_RS08465	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_RS08470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7C91_RS08475	COG0651	ATP synthesis coupled electron transport
A7C91_RS08480	COG0651	ATP synthesis coupled electron transport
A7C91_RS08485	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_RS08490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_RS08490	COG2111	Na H antiporter
A7C91_RS08500	COG1320	monovalent cation:proton antiporter activity
A7C91_RS08505	COG2212	antiporter activity
A7C91_RS08510	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_RS08520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7C91_RS08545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7C91_RS08565	COG0018	arginyl-trna synthetase
A7C91_RS08570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7C91_RS08640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A7C91_RS08660	COG0301	tRNA thio-modification
A7C91_RS08660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7C91_RS08665	COG1836	PFAM Integral membrane protein DUF92
A7C91_RS08670	COG1522	sequence-specific DNA binding
A7C91_RS08680	COG0640	Transcriptional regulator
A7C91_RS08700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7C91_RS08705	COG0396	ATPase activity
A7C91_RS08710	COG0719	Fe-S assembly protein
A7C91_RS08730	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
A7C91_RS08750	COG3383	formate dehydrogenase (NAD+) activity
A7C91_RS08765	COG0493	'glutamate synthase
A7C91_RS08780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7C91_RS08790	COG1476	TRANSCRIPTIONal
A7C91_RS08825	COG1515	deoxyribonuclease V activity
A7C91_RS08835	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A7C91_RS08845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A7C91_RS08860	COG0436	Aminotransferase
A7C91_RS08865	COG2192	nodulation
A7C91_RS08875	COG0442	prolyl-tRNA aminoacylation
A7C91_RS08880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7C91_RS08890	COG0730	response to heat
A7C91_RS08915	COG0720	synthase
A7C91_RS08930	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS08935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7C91_RS08935	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS08945	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS08950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7C91_RS08950	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS08965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A7C91_RS08995	COG1744	ABC transporter substrate-binding protein PnrA-like
A7C91_RS09000	COG3845	ABC transporter
A7C91_RS09005	COG4603	Belongs to the binding-protein-dependent transport system permease family
A7C91_RS09010	COG1079	Belongs to the binding-protein-dependent transport system permease family
A7C91_RS09030	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A7C91_RS09035	COG0215	cysteine-tRNA ligase activity
A7C91_RS09055	COG1136	(ABC) transporter
A7C91_RS09065	COG0352	thiamine-phosphate diphosphorylase activity
A7C91_RS09065	COG0351	phosphomethylpyrimidine kinase
A7C91_RS09070	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A7C91_RS09075	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A7C91_RS09080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7C91_RS09095	COG1505	serine-type exopeptidase activity
A7C91_RS09100	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_RS09105	COG1201	RNA secondary structure unwinding
A7C91_RS09115	COG1215	transferase activity, transferring glycosyl groups
A7C91_RS09195	COG2096	Adenosyltransferase
A7C91_RS09205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_RS09210	COG1546	Belongs to the CinA family
A7C91_RS09210	COG1058	Belongs to the CinA family
A7C91_RS09215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7C91_RS09225	COG1872	DUF167
A7C91_RS09235	COG0423	glycine-tRNA ligase activity
A7C91_RS09250	COG0534	Mate efflux family protein
A7C91_RS09270	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A7C91_RS09285	COG0006	proline dipeptidase activity
A7C91_RS09300	COG0482	sulfurtransferase activity
A7C91_RS09325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A7C91_RS09335	COG0163	prenyltransferase activity
A7C91_RS09360	COG0012	GTP binding
A7C91_RS09375	COG2078	PFAM AMMECR1 domain protein
A7C91_RS09380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_RS09380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_RS09385	COG1131	(ABC) transporter
A7C91_RS09415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7C91_RS09450	COG0312	modulator of DNA gyrase
A7C91_RS09460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_RS09485	COG0525	valine-tRNA ligase activity
A7C91_RS09500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7C91_RS09505	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A7C91_RS09530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A7C91_RS09535	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_RS09555	COG1492	cobalamin metabolic process
A7C91_RS09560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A7C91_RS09575	COG0303	'Molybdopterin
A7C91_RS09600	COG1078	dGTPase activity
A7C91_RS09625	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A7C91_RS09630	COG0493	'glutamate synthase
A7C91_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
A7C91_RS09655	COG0459	protein refolding
A7C91_RS09695	COG0315	cyclic pyranopterin monophosphate synthase activity
A7C91_RS09710	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A7C91_RS09710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_RS09735	COG1216	Glycosyl transferase, family 2
A7C91_RS09765	COG1739	Uncharacterized protein family UPF0029
A7C91_RS09780	COG1121	(ABC) transporter
A7C91_RS09800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_RS09845	COG0617	tRNA 3'-terminal CCA addition
A7C91_RS09845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7C91_RS09845	COG0517	IMP dehydrogenase activity
A7C91_RS09860	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A7C91_RS09880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_RS09885	COG2414	aldehyde ferredoxin oxidoreductase
A7C91_RS09920	COG0051	transcription antitermination factor activity, RNA binding
A7C91_RS09925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7C91_RS09935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7C91_RS09980	COG1469	GTP cyclohydrolase I activity
A7C91_RS09990	COG1401	restriction endodeoxyribonuclease activity
A7C91_RS10015	COG2205	protein histidine kinase activity
A7C91_RS10035	COG1121	(ABC) transporter
A7C91_RS10045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7C91_RS10065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7C91_RS10080	COG2226	methyltransferase
A7C91_RS10085	COG0011	TIGRFAM Protein of
A7C91_RS10095	COG0563	adenylate kinase activity
A7C91_RS10115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7C91_RS10160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7C91_RS10165	COG1993	acr, cog1993
A7C91_RS10185	COG1794	racemase activity, acting on amino acids and derivatives
A7C91_RS10195	COG0312	modulator of DNA gyrase
A7C91_RS10200	COG0312	modulator of DNA gyrase
A7C91_RS10275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7C91_RS10280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7C91_RS10315	COG0243	molybdopterin cofactor binding
A7C91_RS10320	COG0450	alkyl hydroperoxide reductase
A7C91_RS10375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_RS10390	COG2217	Heavy metal translocating P-type atpase
A7C91_RS10410	COG0450	alkyl hydroperoxide reductase
A7C91_RS10430	COG0719	Fe-S assembly protein
A7C91_RS10440	COG0396	ATPase activity
A7C91_RS10445	COG1528	Iron-storage protein
A7C91_RS10450	COG0301	tRNA thio-modification
A7C91_RS10455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7C91_RS10460	COG0778	Nitroreductase
A7C91_RS10490	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_RS10495	COG0450	alkyl hydroperoxide reductase
A7C91_RS10500	COG0426	domain, Protein
A7C91_RS10515	COG1592	Rubrerythrin
A7C91_RS10520	COG1773	rubredoxin
A7C91_RS10525	COG2033	superoxide reductase activity
A7C91_RS10580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7C91_RS10590	COG0131	Imidazoleglycerol-phosphate dehydratase
A7C91_RS10595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7C91_RS10605	COG0107	imidazoleglycerol-phosphate synthase activity
A7C91_RS10610	COG0140	phosphoribosyl-ATP diphosphatase activity
A7C91_RS10610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7C91_RS10615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7C91_RS10675	COG1605	Chorismate mutase
A7C91_RS10675	COG0077	Prephenate dehydratase