locus-tag	class	description
A3L09_RS00015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L09_RS00025	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L09_RS00025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L09_RS00045	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L09_RS00050	COG0516	GMP reductase activity
A3L09_RS00050	COG0517	IMP dehydrogenase activity
A3L09_RS00055	COG0475	glutathione-regulated potassium exporter activity
A3L09_RS00060	COG0475	glutathione-regulated potassium exporter activity
A3L09_RS00065	COG2095	MarC family integral membrane protein
A3L09_RS00070	COG0124	histidyl-tRNA synthetase
A3L09_RS00110	COG0681	Belongs to the peptidase S26 family
A3L09_RS00120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L09_RS00160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3L09_RS00170	COG2894	cell division
A3L09_RS00240	COG1506	peptidase
A3L09_RS00240	COG0823	Involved in the tonB-independent uptake of proteins
A3L09_RS00240	COG4946	Tricorn protease homolog
A3L09_RS00270	COG0306	phosphate transporter
A3L09_RS00280	COG1233	COG1233 Phytoene dehydrogenase and related
A3L09_RS00290	COG1980	fructose-bisphosphate aldolase activity
A3L09_RS00315	COG0543	2 iron, 2 sulfur cluster binding
A3L09_RS00320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L09_RS00320	COG0493	'glutamate synthase
A3L09_RS00345	COG1141	Ferredoxin
A3L09_RS00350	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L09_RS00370	COG1404	Belongs to the peptidase S8 family
A3L09_RS00390	COG0528	UMP kinase activity
A3L09_RS00400	COG0167	dihydroorotate dehydrogenase activity
A3L09_RS00415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L09_RS00420	COG1131	(ABC) transporter
A3L09_RS00480	COG0616	signal peptide processing
A3L09_RS00485	COG0330	HflC and HflK could
A3L09_RS00495	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
A3L09_RS00505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L09_RS00510	COG1522	sequence-specific DNA binding
A3L09_RS00515	COG1131	(ABC) transporter
A3L09_RS00545	COG2358	TRAP transporter, solute receptor (TAXI family
A3L09_RS00550	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L09_RS00555	COG0588	phosphoglycerate mutase activity
A3L09_RS00565	COG0546	phosphoglycolate phosphatase activity
A3L09_RS00580	COG1418	mRNA catabolic process
A3L09_RS00590	COG0017	Asparaginyl-tRNA synthetase
A3L09_RS00615	COG0585	pseudouridine synthase activity
A3L09_RS00660	COG0105	UTP biosynthetic process
A3L09_RS00670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3L09_RS00705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L09_RS00710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L09_RS00760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A3L09_RS00770	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
A3L09_RS00785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L09_RS00795	COG0402	S-adenosylhomocysteine deaminase activity
A3L09_RS00805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L09_RS00815	COG1269	ATP hydrolysis coupled proton transport
A3L09_RS00825	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L09_RS00835	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L09_RS00840	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L09_RS00860	COG0840	transmembrane signaling receptor activity
A3L09_RS00865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L09_RS00935	COG1131	(ABC) transporter
A3L09_RS00980	COG1522	sequence-specific DNA binding
A3L09_RS01005	COG0314	molybdopterin synthase activity
A3L09_RS01015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L09_RS01020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A3L09_RS01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L09_RS01040	COG0492	ferredoxin-NADP+ reductase activity
A3L09_RS01050	COG2255	four-way junction helicase activity
A3L09_RS01070	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L09_RS01075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L09_RS01090	COG0714	Associated with various cellular activities
A3L09_RS01110	COG1047	Peptidyl-prolyl cis-trans
A3L09_RS01145	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A3L09_RS01150	COG0116	Belongs to the methyltransferase superfamily
A3L09_RS01155	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L09_RS01175	COG1234	tRNA 3'-trailer cleavage
A3L09_RS01210	COG0148	phosphopyruvate hydratase activity
A3L09_RS01225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L09_RS01250	COG0235	Class ii aldolase
A3L09_RS01260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A3L09_RS01275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L09_RS01290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L09_RS01300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L09_RS01305	COG0306	phosphate transporter
A3L09_RS01320	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS01325	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS01330	COG1144	Oxidoreductase
A3L09_RS01330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L09_RS01335	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS01340	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS01355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L09_RS01355	COG0493	'glutamate synthase
A3L09_RS01360	COG1144	Oxidoreductase
A3L09_RS01365	COG1151	hydroxylamine reductase activity
A3L09_RS01395	COG1528	Iron-storage protein
A3L09_RS01410	COG2226	methyltransferase
A3L09_RS01415	COG1116	anion transmembrane transporter activity
A3L09_RS01425	COG4521	taurine ABC transporter
A3L09_RS01435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A3L09_RS01440	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L09_RS01450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L09_RS01465	COG0535	radical SAM domain protein
A3L09_RS01470	COG1294	oxidase, subunit
A3L09_RS01475	COG1271	oxidase subunit
A3L09_RS01495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A3L09_RS01510	COG0142	geranyltranstransferase activity
A3L09_RS01515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L09_RS01520	COG0651	ATP synthesis coupled electron transport
A3L09_RS01525	COG2212	antiporter activity
A3L09_RS01530	COG1320	monovalent cation:proton antiporter activity
A3L09_RS01545	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L09_RS01550	COG1863	multisubunit Na H antiporter MnhE subunit
A3L09_RS01555	COG0651	ATP synthesis coupled electron transport
A3L09_RS01570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L09_RS01575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L09_RS01580	COG0489	protein tyrosine kinase activity
A3L09_RS01600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L09_RS01600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L09_RS01615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L09_RS01615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L09_RS01625	COG0640	Transcriptional regulator
A3L09_RS01635	COG0640	Transcriptional regulator
A3L09_RS01655	COG2212	antiporter activity
A3L09_RS01660	COG1320	monovalent cation:proton antiporter activity
A3L09_RS01680	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L09_RS01685	COG0651	ATP synthesis coupled electron transport
A3L09_RS01695	COG3260	NADH ubiquinone oxidoreductase 20
A3L09_RS01700	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A3L09_RS01700	COG3261	NADH dehydrogenase
A3L09_RS01710	COG0650	Formate hydrogenlyase subunit 4
A3L09_RS01740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A3L09_RS01780	COG0037	tRNA processing
A3L09_RS01785	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L09_RS01790	COG0750	zinc metalloprotease
A3L09_RS01795	COG0438	transferase activity, transferring glycosyl groups
A3L09_RS01800	COG1216	Glycosyl transferase, family 2
A3L09_RS01800	COG0463	Glycosyl transferase, family 2
A3L09_RS01805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3L09_RS01810	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3L09_RS01840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L09_RS01845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3L09_RS01855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A3L09_RS01865	COG0475	glutathione-regulated potassium exporter activity
A3L09_RS01885	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L09_RS01895	COG0037	tRNA processing
A3L09_RS01905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L09_RS01980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L09_RS01995	COG0312	modulator of DNA gyrase
A3L09_RS02015	COG0434	BtpA family
A3L09_RS02045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L09_RS02080	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L09_RS02085	COG0540	Belongs to the ATCase OTCase family
A3L09_RS02090	COG1992	Thiamine-phosphate synthase
A3L09_RS02090	COG0351	phosphomethylpyrimidine kinase
A3L09_RS02120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L09_RS02135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A3L09_RS02140	COG1530	ribonuclease E activity
A3L09_RS02150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L09_RS02160	COG2255	four-way junction helicase activity
A3L09_RS02165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L09_RS02180	COG0156	8-amino-7-oxononanoate synthase activity
A3L09_RS02195	COG0456	acetyltransferase
A3L09_RS02195	COG1214	PFAM Peptidase M22, glycoprotease
A3L09_RS02200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L09_RS02205	COG1120	ATPase activity
A3L09_RS02210	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L09_RS02260	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L09_RS02265	COG2226	methyltransferase
A3L09_RS02290	COG0537	adenosine 5'-monophosphoramidase activity
A3L09_RS02315	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L09_RS02320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3L09_RS02350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L09_RS02350	COG0517	IMP dehydrogenase activity
A3L09_RS02355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L09_RS02360	COG0511	ligase activity, forming carbon-carbon bonds
A3L09_RS02360	COG5016	pyruvate
A3L09_RS02370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L09_RS02380	COG0305	Participates in initiation and elongation during chromosome replication
A3L09_RS02380	COG1372	Participates in initiation and elongation during chromosome replication
A3L09_RS02405	COG0430	RNA-3'-phosphate cyclase activity
A3L09_RS02420	COG0714	Associated with various cellular activities
A3L09_RS02460	COG0017	Asparaginyl-tRNA synthetase
A3L09_RS02475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L09_RS02480	COG4608	Belongs to the ABC transporter superfamily
A3L09_RS02485	COG0444	Belongs to the ABC transporter superfamily
A3L09_RS02490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L09_RS02495	COG0601	transmembrane transport
A3L09_RS02500	COG4166	transmembrane transport
A3L09_RS02505	COG2723	6-phospho-beta-galactosidase activity
A3L09_RS02545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L09_RS02555	COG0089	rRNA binding
A3L09_RS02560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L09_RS02565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L09_RS02575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L09_RS02580	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L09_RS02595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L09_RS02600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L09_RS02605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L09_RS02615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L09_RS02625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L09_RS02630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3L09_RS02645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L09_RS02650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L09_RS02655	COG1841	ribosomal large subunit assembly
A3L09_RS02660	COG0200	Binds to the 23S rRNA
A3L09_RS02685	COG1102	Psort location Cytoplasmic, score
A3L09_RS02695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L09_RS02710	COG2813	Specifically methylates the guanine in position
A3L09_RS02720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L09_RS02725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L09_RS02735	COG0202	RNA polymerase activity
A3L09_RS02750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L09_RS02755	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L09_RS02775	COG0148	phosphopyruvate hydratase activity
A3L09_RS02780	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L09_RS02820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L09_RS02825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L09_RS02840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L09_RS02865	COG1522	sequence-specific DNA binding
A3L09_RS02875	COG0303	'Molybdopterin
A3L09_RS02880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L09_RS02885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L09_RS02900	COG0009	L-threonylcarbamoyladenylate synthase
A3L09_RS02910	COG0367	asparagine synthase
A3L09_RS02920	COG2894	cell division
A3L09_RS02925	COG4956	integral membrane protein (PIN domain superfamily)
A3L09_RS02930	COG0424	maF-like protein
A3L09_RS02935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A3L09_RS02940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L09_RS02940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L09_RS02950	COG0346	lactoylglutathione lyase activity
A3L09_RS02970	COG0085	RNA polymerase activity
A3L09_RS02975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L09_RS02980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L09_RS03000	COG0049	tRNA binding
A3L09_RS03020	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L09_RS03030	COG2414	aldehyde ferredoxin oxidoreductase
A3L09_RS03055	COG0513	Belongs to the DEAD box helicase family
A3L09_RS03070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L09_RS03080	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3L09_RS03085	COG0058	SHG alpha-glucan phosphorylase activity
A3L09_RS03095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L09_RS03135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L09_RS03140	COG0142	geranyltranstransferase activity
A3L09_RS03160	COG0495	leucyl-tRNA aminoacylation
A3L09_RS03195	COG2119	membrane
A3L09_RS03200	COG0436	Aminotransferase
A3L09_RS03215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L09_RS03220	COG1192	Involved in chromosome partitioning
A3L09_RS03230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L09_RS03230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L09_RS03235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A3L09_RS03240	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L09_RS03255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L09_RS03255	COG1213	nucleotidyl transferase
A3L09_RS03280	COG2442	InterPro IPR007367
A3L09_RS03310	COG0437	4 iron, 4 sulfur cluster binding
A3L09_RS03325	COG1131	(ABC) transporter
A3L09_RS03390	COG0535	radical SAM domain protein
A3L09_RS03395	COG0719	Fe-S assembly protein
A3L09_RS03400	COG1137	ATPase activity
A3L09_RS03420	COG0375	protein maturation
A3L09_RS03425	COG0489	protein tyrosine kinase activity
A3L09_RS03440	COG0746	molybdenum cofactor guanylyltransferase activity
A3L09_RS03445	COG0298	carbon dioxide binding
A3L09_RS03450	COG0409	Hydrogenase expression formation protein
A3L09_RS03455	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L09_RS03470	COG0309	Hydrogenase expression formation protein (HypE)
A3L09_RS03495	COG0651	ATP synthesis coupled electron transport
A3L09_RS03520	COG1320	monovalent cation:proton antiporter activity
A3L09_RS03525	COG2212	antiporter activity
A3L09_RS03530	COG1863	multisubunit Na H antiporter MnhE subunit
A3L09_RS03560	COG1304	FMN binding
A3L09_RS03565	COG2414	aldehyde ferredoxin oxidoreductase
A3L09_RS03570	COG0437	4 iron, 4 sulfur cluster binding
A3L09_RS03580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L09_RS03595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L09_RS03610	COG1346	cytolysis
A3L09_RS03615	COG1380	Effector of murein hydrolase LrgA
A3L09_RS03635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L09_RS03645	COG1573	uracil-dna glycosylase
A3L09_RS03650	COG1757	Na H antiporter
A3L09_RS03665	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A3L09_RS03680	COG1268	BioY protein
A3L09_RS03685	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3L09_RS03685	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3L09_RS03690	COG1122	ATPase activity
A3L09_RS03745	COG0579	oxidoreductase
A3L09_RS03755	COG0584	glycerophosphoryl diester phosphodiesterase
A3L09_RS03765	COG2211	Major facilitator Superfamily
A3L09_RS03785	COG1131	(ABC) transporter
A3L09_RS03790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L09_RS03805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L09_RS03825	COG1178	ABC-type Fe3 transport system permease component
A3L09_RS03830	COG3842	ATPase activity
A3L09_RS03835	COG4143	(ABC) transporter
A3L09_RS03840	COG0733	neurotransmitter:sodium symporter activity
A3L09_RS03850	COG0347	Belongs to the P(II) protein family
A3L09_RS03855	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L09_RS03870	COG0747	negative chemotaxis
A3L09_RS03875	COG0601	transmembrane transport
A3L09_RS03880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L09_RS03885	COG0444	Belongs to the ABC transporter superfamily
A3L09_RS03890	COG4608	Belongs to the ABC transporter superfamily
A3L09_RS03900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L09_RS03910	COG0778	Nitroreductase
A3L09_RS04010	COG1132	(ABC) transporter
A3L09_RS04015	COG1132	(ABC) transporter
A3L09_RS04025	COG1056	cytidyltransferase-related domain
A3L09_RS04025	COG1051	belongs to the nudix hydrolase family
A3L09_RS04060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L09_RS04070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3L09_RS04105	COG1196	nuclear chromosome segregation
A3L09_RS04115	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L09_RS04140	COG1473	amidohydrolase
A3L09_RS04155	COG1984	allophanate hydrolase subunit 2
A3L09_RS04160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L09_RS04165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L09_RS04170	COG4956	integral membrane protein (PIN domain superfamily)
A3L09_RS04175	COG2247	cell wall binding repeat
A3L09_RS04175	COG0860	N-Acetylmuramoyl-L-alanine amidase
A3L09_RS04180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L09_RS04250	COG1042	CoA-binding domain protein
A3L09_RS04250	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L09_RS04250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L09_RS04270	COG2414	aldehyde ferredoxin oxidoreductase
A3L09_RS04275	COG1058	Belongs to the CinA family
A3L09_RS04275	COG1546	Belongs to the CinA family
A3L09_RS04290	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L09_RS04295	COG2361	Protein of unknown function DUF86
A3L09_RS04305	COG1355	regulation of microtubule-based process
A3L09_RS04310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L09_RS04315	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L09_RS04330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L09_RS04335	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L09_RS04340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L09_RS04350	COG1793	dna ligase
A3L09_RS04370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L09_RS04380	COG1201	RNA secondary structure unwinding
A3L09_RS04385	COG0477	Major facilitator Superfamily
A3L09_RS04400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L09_RS04425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L09_RS04430	COG0469	pyruvate kinase activity
A3L09_RS04435	COG0215	cysteine-tRNA ligase activity
A3L09_RS04455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L09_RS04460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L09_RS04530	COG2201	protein-glutamate methylesterase activity
A3L09_RS04535	COG2198	Histidine kinase
A3L09_RS04535	COG0643	Histidine kinase
A3L09_RS04580	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L09_RS04585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L09_RS04595	COG0546	phosphoglycolate phosphatase activity
A3L09_RS04600	COG1363	Peptidase, m42
A3L09_RS04610	COG2409	Drug exporters of the RND superfamily
A3L09_RS04635	COG2814	Major facilitator Superfamily
A3L09_RS04640	COG2096	Adenosyltransferase
A3L09_RS04680	COG0301	tRNA thio-modification
A3L09_RS04690	COG0301	tRNA thio-modification
A3L09_RS04705	COG0051	transcription antitermination factor activity, RNA binding
A3L09_RS04710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L09_RS04725	COG2192	nodulation
A3L09_RS04730	COG0442	prolyl-tRNA aminoacylation
A3L09_RS04735	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L09_RS04760	COG1404	Belongs to the peptidase S8 family
A3L09_RS04765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L09_RS04765	COG0574	Belongs to the PEP-utilizing enzyme family
A3L09_RS04770	COG0534	Mate efflux family protein
A3L09_RS04775	COG0534	Mate efflux family protein
A3L09_RS04780	COG1505	serine-type exopeptidase activity
A3L09_RS04810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L09_RS04825	COG0864	Transcriptional regulator
A3L09_RS04840	COG0501	Belongs to the peptidase M48B family
A3L09_RS04845	COG2131	deaminase
A3L09_RS04855	COG0546	phosphoglycolate phosphatase activity
A3L09_RS04860	COG1522	sequence-specific DNA binding
A3L09_RS04870	COG0693	protein deglycase activity
A3L09_RS04885	COG2264	protein methyltransferase activity
A3L09_RS04890	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L09_RS04920	COG0393	Putative heavy-metal-binding
A3L09_RS04930	COG1695	Transcriptional regulator
A3L09_RS04980	COG2095	MarC family integral membrane protein
A3L09_RS04985	COG1765	OsmC-like protein
A3L09_RS04995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L09_RS05000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L09_RS05010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L09_RS05025	COG1373	ATPase (AAA superfamily
A3L09_RS05040	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L09_RS05050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3L09_RS05055	COG0517	IMP dehydrogenase activity
A3L09_RS05055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L09_RS05090	COG1129	ABC transporter
A3L09_RS05130	COG4974	Belongs to the 'phage' integrase family
A3L09_RS05135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L09_RS05165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L09_RS05180	COG0084	hydrolase, TatD family'
A3L09_RS05195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L09_RS05220	COG0419	ATPase involved in DNA repair
A3L09_RS05220	COG0419	ATPase involved in DNA repair
A3L09_RS05265	COG0423	glycine-tRNA ligase activity
A3L09_RS05270	COG2361	Protein of unknown function DUF86
A3L09_RS05290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L09_RS05295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L09_RS05305	COG0109	protoheme IX farnesyltransferase activity
A3L09_RS05365	COG1744	ABC transporter substrate-binding protein PnrA-like
A3L09_RS05370	COG3845	ABC transporter
A3L09_RS05375	COG4603	Belongs to the binding-protein-dependent transport system permease family
A3L09_RS05380	COG1079	Belongs to the binding-protein-dependent transport system permease family
A3L09_RS05415	COG0616	signal peptide processing
A3L09_RS05425	COG0628	permease
A3L09_RS05430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L09_RS05455	COG1131	(ABC) transporter
A3L09_RS05465	COG0556	nucleotide-excision repair
A3L09_RS05470	COG0101	tRNA pseudouridine synthase activity
A3L09_RS05480	COG0463	Glycosyl transferase, family 2
A3L09_RS05495	COG0504	CTP synthase activity
A3L09_RS05530	COG0243	molybdopterin cofactor binding
A3L09_RS05625	COG0840	transmembrane signaling receptor activity
A3L09_RS05630	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L09_RS05655	COG0417	DNA replication proofreading
A3L09_RS05665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L09_RS05665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L09_RS05675	COG2078	PFAM AMMECR1 domain protein
A3L09_RS05680	COG0011	TIGRFAM Protein of
A3L09_RS05765	COG0543	2 iron, 2 sulfur cluster binding
A3L09_RS05775	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A3L09_RS05780	COG1695	Transcriptional regulator
A3L09_RS05790	COG0252	asparaginase activity
A3L09_RS05825	COG3842	ATPase activity
A3L09_RS05830	COG4149	molybdate abc transporter
A3L09_RS05840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3L09_RS05850	COG0534	Mate efflux family protein
A3L09_RS05870	COG1830	Aldolase
A3L09_RS05875	COG1301	dicarboxylic acid transport
A3L09_RS05880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3L09_RS05880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3L09_RS05890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L09_RS05900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L09_RS05920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L09_RS05960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L09_RS05960	COG0321	lipoyl(octanoyl) transferase activity
A3L09_RS05965	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L09_RS05990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A3L09_RS06015	COG1518	maintenance of DNA repeat elements
A3L09_RS06055	COG0560	Phosphoserine phosphatase
A3L09_RS06070	COG2234	aminopeptidase activity
A3L09_RS06085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_RS06110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L09_RS06180	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A3L09_RS06185	COG0840	transmembrane signaling receptor activity
A3L09_RS06200	COG0643	Histidine kinase
A3L09_RS06200	COG2198	Histidine kinase
A3L09_RS06205	COG2201	protein-glutamate methylesterase activity
A3L09_RS06210	COG2201	protein-glutamate methylesterase activity
A3L09_RS06215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A3L09_RS06225	COG0835	chemotaxis
A3L09_RS06240	COG0006	proline dipeptidase activity
A3L09_RS06260	COG0475	glutathione-regulated potassium exporter activity
A3L09_RS06290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L09_RS06300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L09_RS06315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L09_RS06325	COG0735	belongs to the Fur family
A3L09_RS06345	COG0668	transmembrane transport
A3L09_RS06360	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L09_RS06365	COG0450	alkyl hydroperoxide reductase
A3L09_RS06370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L09_RS06370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A3L09_RS06375	COG0307	riboflavin synthase, alpha
A3L09_RS06380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3L09_RS06380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A3L09_RS06385	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A3L09_RS06395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L09_RS06410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L09_RS06420	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A3L09_RS06425	COG0352	thiamine-phosphate diphosphorylase activity
A3L09_RS06425	COG0351	phosphomethylpyrimidine kinase
A3L09_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
A3L09_RS06450	COG1881	PFAM PEBP family protein
A3L09_RS06455	COG2226	methyltransferase
A3L09_RS06465	COG0525	valine-tRNA ligase activity
A3L09_RS06505	COG1373	ATPase (AAA superfamily
A3L09_RS06515	COG0312	modulator of DNA gyrase
A3L09_RS06530	COG0598	Magnesium transport protein CorA
A3L09_RS06545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L09_RS06575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L09_RS06575	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS06580	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS06600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L09_RS06600	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS06605	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L09_RS06650	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L09_RS06665	COG1160	GTP binding
A3L09_RS06680	COG1469	GTP cyclohydrolase I activity
A3L09_RS06705	COG2205	protein histidine kinase activity
A3L09_RS06710	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L09_RS06750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L09_RS06750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L09_RS06760	COG1446	asparaginase
A3L09_RS06770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L09_RS06790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L09_RS06800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L09_RS06810	COG0483	inositol monophosphate 1-phosphatase activity
A3L09_RS06820	COG1979	alcohol dehydrogenase
A3L09_RS06830	COG1078	dGTPase activity
A3L09_RS06835	COG0436	Aminotransferase
A3L09_RS06840	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L09_RS06840	COG2050	protein possibly involved in aromatic compounds catabolism
A3L09_RS06845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L09_RS06860	COG1444	tRNA N-acetyltransferase activity
A3L09_RS06870	COG4946	Tricorn protease homolog
A3L09_RS06870	COG1506	peptidase
A3L09_RS06870	COG0823	Involved in the tonB-independent uptake of proteins
A3L09_RS06880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L09_RS06895	COG0563	adenylate kinase activity
A3L09_RS06905	COG1966	Carbon starvation protein
A3L09_RS06920	COG0003	Pfam Anion-transporting ATPase
A3L09_RS06935	COG2267	carboxylic ester hydrolase activity
A3L09_RS06965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L09_RS07010	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L09_RS07015	COG2033	superoxide reductase activity
A3L09_RS07020	COG1773	rubredoxin
A3L09_RS07025	COG1592	Rubrerythrin
A3L09_RS07040	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L09_RS07055	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L09_RS07065	COG4555	ABC transporter
A3L09_RS07075	COG0493	'glutamate synthase
A3L09_RS07075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L09_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
A3L09_RS07085	COG0501	Belongs to the peptidase M48B family
A3L09_RS07115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L09_RS07120	COG0668	transmembrane transport
A3L09_RS07220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L09_RS07235	COG2815	serine threonine protein kinase
A3L09_RS07235	COG0515	serine threonine protein kinase
A3L09_RS07265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3L09_RS07320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L09_RS07320	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L09_RS07340	COG1850	ribulose-bisphosphate carboxylase activity
A3L09_RS07350	COG1078	dGTPase activity
A3L09_RS07360	COG0126	phosphoglycerate kinase activity
A3L09_RS07365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L09_RS07395	COG1872	DUF167
A3L09_RS07405	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L09_RS07410	COG1794	racemase activity, acting on amino acids and derivatives
A3L09_RS07425	COG1993	acr, cog1993
A3L09_RS07430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L09_RS07475	COG1110	DNA topoisomerase II activity
A3L09_RS07505	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L09_RS07505	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L09_RS07515	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L09_RS07545	COG1205	dead DEAH box helicase
A3L09_RS07545	COG1111	helicase
A3L09_RS07555	COG1739	Uncharacterized protein family UPF0029
A3L09_RS07580	COG1335	isochorismatase
A3L09_RS07635	COG1476	TRANSCRIPTIONal
A3L09_RS07640	COG1131	(ABC) transporter
A3L09_RS07725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L09_RS07735	COG0018	arginyl-trna synthetase
A3L09_RS07750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L09_RS07760	COG1863	multisubunit Na H antiporter MnhE subunit
A3L09_RS07765	COG2212	antiporter activity
A3L09_RS07770	COG1320	monovalent cation:proton antiporter activity
A3L09_RS07780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L09_RS07780	COG2111	Na H antiporter
A3L09_RS07790	COG0651	ATP synthesis coupled electron transport
A3L09_RS07795	COG0651	ATP synthesis coupled electron transport
A3L09_RS07805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L09_RS07810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L09_RS07815	COG0649	NAD binding
A3L09_RS07835	COG1522	sequence-specific DNA binding
A3L09_RS07855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L09_RS07870	COG0306	phosphate transporter
A3L09_RS07890	COG2894	cell division
A3L09_RS07895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L09_RS07900	COG1063	alcohol dehydrogenase
A3L09_RS07905	COG2886	Uncharacterised protein family (UPF0175)
A3L09_RS07945	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L09_RS07955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L09_RS07985	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L09_RS08005	COG0012	GTP binding
A3L09_RS08020	COG0163	prenyltransferase activity
A3L09_RS08030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A3L09_RS08040	COG1918	ferrous iron import across plasma membrane
A3L09_RS08040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L09_RS08055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L09_RS08085	COG0006	proline dipeptidase activity
A3L09_RS08110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A3L09_RS08110	COG1321	iron dependent repressor
A3L09_RS08115	COG1121	(ABC) transporter
A3L09_RS08130	COG1234	tRNA 3'-trailer cleavage
A3L09_RS08145	COG1994	Peptidase M50
A3L09_RS08150	COG2140	Oxalate decarboxylase
A3L09_RS08165	COG0436	Aminotransferase
A3L09_RS08185	COG1215	transferase activity, transferring glycosyl groups
A3L09_RS08200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L09_RS08205	COG0252	asparaginase activity
A3L09_RS08215	COG1515	deoxyribonuclease V activity
A3L09_RS08260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L09_RS08265	COG0509	glycine decarboxylation via glycine cleavage system
A3L09_RS08275	COG0297	glycogen (starch) synthase activity
A3L09_RS08295	COG0493	'glutamate synthase
A3L09_RS08300	COG0543	2 iron, 2 sulfur cluster binding
A3L09_RS08335	COG0601	transmembrane transport
A3L09_RS08340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L09_RS08345	COG0444	Belongs to the ABC transporter superfamily
A3L09_RS08350	COG4608	Belongs to the ABC transporter superfamily
A3L09_RS08380	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3L09_RS08425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L09_RS08430	COG0024	Methionine aminopeptidase
A3L09_RS08440	COG0517	IMP dehydrogenase activity
A3L09_RS08440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L09_RS08450	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L09_RS08455	COG0656	L-ascorbic acid biosynthetic process
A3L09_RS08490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L09_RS08490	COG1042	CoA-binding domain protein
A3L09_RS08490	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L09_RS08515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L09_RS08530	COG0151	Belongs to the GarS family
A3L09_RS08550	COG0047	phosphoribosylformylglycinamidine synthase activity
A3L09_RS08555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L09_RS08555	COG0574	Belongs to the PEP-utilizing enzyme family
A3L09_RS08560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L09_RS08575	COG0517	IMP dehydrogenase activity
A3L09_RS08575	COG0516	GMP reductase activity
A3L09_RS08580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L09_RS08580	COG0519	Catalyzes the synthesis of GMP from XMP
A3L09_RS08595	COG0519	Catalyzes the synthesis of GMP from XMP
A3L09_RS08595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L09_RS08660	COG1851	Uncharacterised protein family (UPF0128)
A3L09_RS08665	COG2379	hydroxypyruvate reductase
A3L09_RS08690	COG1832	CoA-binding protein
A3L09_RS08720	COG0432	Pfam Uncharacterised protein family UPF0047
A3L09_RS08730	COG1199	ATP-dependent helicase activity
A3L09_RS08750	COG1489	DNA binding
A3L09_RS08775	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L09_RS08790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L09_RS08825	COG0402	S-adenosylhomocysteine deaminase activity
A3L09_RS08830	COG0017	Asparaginyl-tRNA synthetase
A3L09_RS08870	COG4208	sulfate ABC transporter
A3L09_RS08875	COG3842	ATPase activity
A3L09_RS08910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_RS08945	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L09_RS08950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L09_RS08955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L09_RS08960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L09_RS08975	COG3383	formate dehydrogenase (NAD+) activity
A3L09_RS08980	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3L09_RS08985	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A3L09_RS09015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L09_RS09020	COG4608	Belongs to the ABC transporter superfamily
A3L09_RS09025	COG0444	Belongs to the ABC transporter superfamily
A3L09_RS09035	COG0601	transmembrane transport
A3L09_RS09075	COG0297	glycogen (starch) synthase activity
A3L09_RS09085	COG0438	transferase activity, transferring glycosyl groups
A3L09_RS09090	COG0395	ABC-type sugar transport system, permease component
A3L09_RS09095	COG1175	transmembrane transport
A3L09_RS09100	COG1653	transport
A3L09_RS09110	COG1378	Sugar-specific transcriptional regulator TrmB
A3L09_RS09125	COG1175	transmembrane transport
A3L09_RS09130	COG3833	ABC-type maltose transport systems, permease component
A3L09_RS09140	COG3842	ATPase activity
A3L09_RS09150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L09_RS09155	COG1234	tRNA 3'-trailer cleavage
A3L09_RS09160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L09_RS09195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A3L09_RS09200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L09_RS09225	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L09_RS09240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L09_RS09255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L09_RS09265	COG0157	Belongs to the NadC ModD family
A3L09_RS09285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L09_RS09315	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L09_RS09320	COG1201	RNA secondary structure unwinding
A3L09_RS09320	COG1201	RNA secondary structure unwinding
A3L09_RS09370	COG1342	Belongs to the UPF0251 family
A3L09_RS09375	COG0455	bacterial-type flagellum organization
A3L09_RS09380	COG0489	protein tyrosine kinase activity
A3L09_RS09385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_RS09385	COG0731	radical SAM domain protein
A3L09_RS09455	COG0719	Fe-S assembly protein
A3L09_RS09460	COG0396	ATPase activity
A3L09_RS09480	COG0730	response to heat
A3L09_RS09485	COG0730	response to heat
A3L09_RS09495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L09_RS09500	COG0546	phosphoglycolate phosphatase activity
A3L09_RS09510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L09_RS09515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3L09_RS09520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A3L09_RS09550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3L09_RS09555	COG2342	PFAM TM1410 hypothetical-related protein
A3L09_RS09560	COG0746	molybdenum cofactor guanylyltransferase activity
A3L09_RS09575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3L09_RS09590	COG0175	sulfate reduction
A3L09_RS09620	COG0515	serine threonine protein kinase
A3L09_RS09620	COG2815	serine threonine protein kinase
A3L09_RS09640	COG2815	serine threonine protein kinase
A3L09_RS09640	COG0515	serine threonine protein kinase
A3L09_RS09645	COG0631	protein serine/threonine phosphatase activity
A3L09_RS09650	COG2815	serine threonine protein kinase
A3L09_RS09650	COG0515	serine threonine protein kinase
A3L09_RS09660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L09_RS09665	COG0515	serine threonine protein kinase
A3L09_RS09665	COG2815	serine threonine protein kinase
A3L09_RS09670	COG0330	HflC and HflK could
A3L09_RS09680	COG1435	thymidine kinase activity
A3L09_RS09695	COG0511	ligase activity, forming carbon-carbon bonds
A3L09_RS09695	COG5016	pyruvate
A3L09_RS09700	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L09_RS09780	COG0717	Belongs to the dCTP deaminase family
A3L09_RS09795	COG0081	regulation of translation
A3L09_RS09800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L09_RS09815	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L09_RS09830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L09_RS09860	COG1458	PINc domain ribonuclease
A3L09_RS09925	COG1522	sequence-specific DNA binding
A3L09_RS09950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L09_RS09955	COG0183	Belongs to the thiolase family
A3L09_RS10030	COG0438	transferase activity, transferring glycosyl groups
A3L09_RS10040	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L09_RS10050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L09_RS10070	COG0010	Belongs to the arginase family
A3L09_RS10110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L09_RS10175	COG0438	transferase activity, transferring glycosyl groups
A3L09_RS10195	COG0463	Glycosyl transferase, family 2
A3L09_RS10210	COG0714	Associated with various cellular activities
A3L09_RS10255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L09_RS10270	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L09_RS10295	COG0697	spore germination
A3L09_RS10320	COG0297	glycogen (starch) synthase activity
A3L09_RS10365	COG0589	response to stress
A3L09_RS10370	COG1628	Protein of unknown function DUF99
A3L09_RS10380	COG1254	Belongs to the acylphosphatase family
A3L09_RS10425	COG0174	glutamine synthetase
A3L09_RS10440	COG4608	Belongs to the ABC transporter superfamily
A3L09_RS10445	COG0444	Belongs to the ABC transporter superfamily
A3L09_RS10450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L09_RS10455	COG0601	transmembrane transport
A3L09_RS10465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3L09_RS10470	COG0543	2 iron, 2 sulfur cluster binding
A3L09_RS10505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L09_RS10510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A3L09_RS10520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L09_RS10530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3L09_RS10540	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A3L09_RS10545	COG0281	malic enzyme
A3L09_RS10565	COG0095	Lipoate-protein ligase
A3L09_RS10600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L09_RS10610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L09_RS10615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L09_RS10620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L09_RS10625	COG0569	domain protein