locus-tag	class	description
A3L10_RS00005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L10_RS00010	COG0560	Phosphoserine phosphatase
A3L10_RS00045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L10_RS00075	COG1056	cytidyltransferase-related domain
A3L10_RS00075	COG1051	belongs to the nudix hydrolase family
A3L10_RS00135	COG0456	acetyltransferase
A3L10_RS00140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS00170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L10_RS00170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L10_RS00180	COG0778	Nitroreductase
A3L10_RS00185	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L10_RS00195	COG4608	Belongs to the ABC transporter superfamily
A3L10_RS00200	COG0444	Belongs to the ABC transporter superfamily
A3L10_RS00205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L10_RS00210	COG0601	transmembrane transport
A3L10_RS00215	COG0747	negative chemotaxis
A3L10_RS00255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L10_RS00260	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L10_RS00270	COG1793	dna ligase
A3L10_RS00270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L10_RS00285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L10_RS00285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L10_RS00360	COG1042	CoA-binding domain protein
A3L10_RS00360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS00360	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L10_RS00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L10_RS00390	COG0303	'Molybdopterin
A3L10_RS00395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L10_RS00420	COG0009	L-threonylcarbamoyladenylate synthase
A3L10_RS00435	COG0367	asparagine synthase
A3L10_RS00445	COG2894	cell division
A3L10_RS00480	COG0424	maF-like protein
A3L10_RS00490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L10_RS00490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L10_RS00500	COG0346	lactoylglutathione lyase activity
A3L10_RS00510	COG1196	nuclear chromosome segregation
A3L10_RS00535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L10_RS00550	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L10_RS00565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L10_RS00580	COG2894	cell division
A3L10_RS00585	COG0330	HflC and HflK could
A3L10_RS00600	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A3L10_RS00620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L10_RS00625	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L10_RS00630	COG1984	allophanate hydrolase subunit 2
A3L10_RS00640	COG1454	alcohol dehydrogenase
A3L10_RS00650	COG0483	inositol monophosphate 1-phosphatase activity
A3L10_RS00655	COG0457	Tetratricopeptide repeat
A3L10_RS00655	COG0705	Rhomboid family
A3L10_RS00710	COG1489	DNA binding
A3L10_RS00715	COG1215	transferase activity, transferring glycosyl groups
A3L10_RS00740	COG3473	Maleate cis-trans isomerase
A3L10_RS00755	COG0301	tRNA thio-modification
A3L10_RS00775	COG0301	tRNA thio-modification
A3L10_RS00805	COG2814	Major facilitator Superfamily
A3L10_RS00810	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L10_RS00810	COG1042	CoA-binding domain protein
A3L10_RS00810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS00850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L10_RS00890	COG0126	phosphoglycerate kinase activity
A3L10_RS00915	COG3842	ATPase activity
A3L10_RS00920	COG1178	ABC-type Fe3 transport system permease component
A3L10_RS00940	COG1522	sequence-specific DNA binding
A3L10_RS00965	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3L10_RS00970	COG1122	ATPase activity
A3L10_RS00975	COG1268	BioY protein
A3L10_RS00990	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
A3L10_RS01005	COG4946	Tricorn protease homolog
A3L10_RS01005	COG1506	peptidase
A3L10_RS01005	COG0823	Involved in the tonB-independent uptake of proteins
A3L10_RS01010	COG1444	tRNA N-acetyltransferase activity
A3L10_RS01030	COG4143	(ABC) transporter
A3L10_RS01045	COG0017	Asparaginyl-tRNA synthetase
A3L10_RS01105	COG0402	S-adenosylhomocysteine deaminase activity
A3L10_RS01120	COG0175	sulfate reduction
A3L10_RS01150	COG0105	UTP biosynthetic process
A3L10_RS01160	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3L10_RS01165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L10_RS01170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L10_RS01200	COG0084	hydrolase, TatD family'
A3L10_RS01215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L10_RS01220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L10_RS01225	COG1201	RNA secondary structure unwinding
A3L10_RS01250	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L10_RS01275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L10_RS01280	COG1342	Belongs to the UPF0251 family
A3L10_RS01370	COG0489	protein tyrosine kinase activity
A3L10_RS01410	COG2267	carboxylic ester hydrolase activity
A3L10_RS01425	COG0003	Pfam Anion-transporting ATPase
A3L10_RS01440	COG1966	Carbon starvation protein
A3L10_RS01450	COG1830	Aldolase
A3L10_RS01455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A3L10_RS01455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A3L10_RS01460	COG1301	dicarboxylic acid transport
A3L10_RS01470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L10_RS01480	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L10_RS01485	COG1518	maintenance of DNA repeat elements
A3L10_RS01505	COG1337	RAMP superfamily
A3L10_RS01515	COG1353	crispr-associated protein
A3L10_RS01525	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L10_RS01535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L10_RS01540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A3L10_RS01540	COG0140	phosphoribosyl-ATP diphosphatase activity
A3L10_RS01545	COG0107	imidazoleglycerol-phosphate synthase activity
A3L10_RS01550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A3L10_RS01555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A3L10_RS01560	COG0131	Imidazoleglycerol-phosphate dehydratase
A3L10_RS01570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3L10_RS01600	COG0735	belongs to the Fur family
A3L10_RS01645	COG2033	superoxide reductase activity
A3L10_RS01650	COG1773	rubredoxin
A3L10_RS01655	COG1592	Rubrerythrin
A3L10_RS01680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L10_RS01685	COG0640	Transcriptional regulator
A3L10_RS01690	COG2217	Heavy metal translocating P-type atpase
A3L10_RS01695	COG0456	acetyltransferase
A3L10_RS01700	COG2217	Heavy metal translocating P-type atpase
A3L10_RS01720	COG2226	methyltransferase
A3L10_RS01740	COG0450	alkyl hydroperoxide reductase
A3L10_RS01745	COG0243	molybdopterin cofactor binding
A3L10_RS01790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L10_RS01820	COG0477	Major facilitator Superfamily
A3L10_RS01830	COG0312	modulator of DNA gyrase
A3L10_RS01835	COG0312	modulator of DNA gyrase
A3L10_RS01845	COG1794	racemase activity, acting on amino acids and derivatives
A3L10_RS01855	COG0668	transmembrane transport
A3L10_RS01865	COG1993	acr, cog1993
A3L10_RS01870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L10_RS01915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L10_RS01935	COG0563	adenylate kinase activity
A3L10_RS01950	COG0011	TIGRFAM Protein of
A3L10_RS01955	COG2226	methyltransferase
A3L10_RS01970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L10_RS01990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3L10_RS02000	COG1121	(ABC) transporter
A3L10_RS02020	COG2205	protein histidine kinase activity
A3L10_RS02045	COG1469	GTP cyclohydrolase I activity
A3L10_RS02050	COG1078	dGTPase activity
A3L10_RS02055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L10_RS02060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L10_RS02065	COG0051	transcription antitermination factor activity, RNA binding
A3L10_RS02075	COG2414	aldehyde ferredoxin oxidoreductase
A3L10_RS02080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L10_RS02105	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L10_RS02155	COG1129	ABC transporter
A3L10_RS02165	COG1111	helicase
A3L10_RS02165	COG1205	dead DEAH box helicase
A3L10_RS02175	COG1739	Uncharacterized protein family UPF0029
A3L10_RS02205	COG0463	Glycosyl transferase, family 2
A3L10_RS02220	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L10_RS02220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L10_RS02250	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L10_RS02260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3L10_RS02265	COG0515	serine threonine protein kinase
A3L10_RS02275	COG0459	protein refolding
A3L10_RS02285	COG0501	Belongs to the peptidase M48B family
A3L10_RS02290	COG0402	S-adenosylhomocysteine deaminase activity
A3L10_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
A3L10_RS02300	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L10_RS02305	COG0277	FAD linked oxidase domain protein
A3L10_RS02315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A3L10_RS02345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS02355	COG1078	dGTPase activity
A3L10_RS02380	COG0303	'Molybdopterin
A3L10_RS02385	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3L10_RS02395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3L10_RS02400	COG1492	cobalamin metabolic process
A3L10_RS02410	COG0746	molybdenum cofactor guanylyltransferase activity
A3L10_RS02415	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3L10_RS02435	COG1573	uracil-dna glycosylase
A3L10_RS02440	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3L10_RS02445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L10_RS02450	COG2226	methyltransferase
A3L10_RS02455	COG0525	valine-tRNA ligase activity
A3L10_RS02475	COG2264	protein methyltransferase activity
A3L10_RS02485	COG0312	modulator of DNA gyrase
A3L10_RS02500	COG0598	Magnesium transport protein CorA
A3L10_RS02505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L10_RS02510	COG0012	GTP binding
A3L10_RS02525	COG0163	prenyltransferase activity
A3L10_RS02550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L10_RS02550	COG1918	ferrous iron import across plasma membrane
A3L10_RS02565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L10_RS02580	COG0006	proline dipeptidase activity
A3L10_RS02595	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L10_RS02605	COG0534	Mate efflux family protein
A3L10_RS02620	COG0423	glycine-tRNA ligase activity
A3L10_RS02625	COG2361	Protein of unknown function DUF86
A3L10_RS02640	COG1872	DUF167
A3L10_RS02645	COG0384	phenazine biosynthesis protein PhzF
A3L10_RS02655	COG1546	Belongs to the CinA family
A3L10_RS02655	COG1058	Belongs to the CinA family
A3L10_RS02675	COG2096	Adenosyltransferase
A3L10_RS02685	COG2814	Major facilitator Superfamily
A3L10_RS02710	COG1363	Peptidase, m42
A3L10_RS02785	COG1201	RNA secondary structure unwinding
A3L10_RS02790	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L10_RS02795	COG1505	serine-type exopeptidase activity
A3L10_RS02800	COG0351	phosphomethylpyrimidine kinase
A3L10_RS02800	COG0352	thiamine-phosphate diphosphorylase activity
A3L10_RS02805	COG0352	thiamine-phosphate diphosphorylase activity
A3L10_RS02810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A3L10_RS02835	COG1047	Peptidyl-prolyl cis-trans
A3L10_RS02840	COG0215	cysteine-tRNA ligase activity
A3L10_RS02865	COG1079	Belongs to the binding-protein-dependent transport system permease family
A3L10_RS02870	COG4603	Belongs to the binding-protein-dependent transport system permease family
A3L10_RS02875	COG3845	ABC transporter
A3L10_RS02880	COG1744	ABC transporter substrate-binding protein PnrA-like
A3L10_RS02895	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L10_RS02910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L10_RS02910	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS02915	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS02925	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS02925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L10_RS02930	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS02945	COG2361	Protein of unknown function DUF86
A3L10_RS02980	COG0730	response to heat
A3L10_RS02990	COG0730	response to heat
A3L10_RS03000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L10_RS03005	COG0442	prolyl-tRNA aminoacylation
A3L10_RS03015	COG2192	nodulation
A3L10_RS03030	COG0436	Aminotransferase
A3L10_RS03040	COG0501	Belongs to the peptidase M48B family
A3L10_RS03045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L10_RS03055	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L10_RS03065	COG1515	deoxyribonuclease V activity
A3L10_RS03125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L10_RS03155	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
A3L10_RS03160	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A3L10_RS03175	COG0719	Fe-S assembly protein
A3L10_RS03180	COG0396	ATPase activity
A3L10_RS03205	COG0640	Transcriptional regulator
A3L10_RS03215	COG1522	sequence-specific DNA binding
A3L10_RS03220	COG1836	PFAM Integral membrane protein DUF92
A3L10_RS03245	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3L10_RS03315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L10_RS03320	COG0018	arginyl-trna synthetase
A3L10_RS03340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L10_RS03355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L10_RS03365	COG1863	multisubunit Na H antiporter MnhE subunit
A3L10_RS03370	COG2212	antiporter activity
A3L10_RS03375	COG1320	monovalent cation:proton antiporter activity
A3L10_RS03385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L10_RS03385	COG2111	Na H antiporter
A3L10_RS03395	COG0651	ATP synthesis coupled electron transport
A3L10_RS03400	COG0651	ATP synthesis coupled electron transport
A3L10_RS03410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L10_RS03420	COG0649	NAD binding
A3L10_RS03450	COG1522	sequence-specific DNA binding
A3L10_RS03500	COG1881	PFAM PEBP family protein
A3L10_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
A3L10_RS03530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L10_RS03550	COG0602	queuosine metabolic process
A3L10_RS03600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3L10_RS03615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L10_RS03615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L10_RS03625	COG0656	L-ascorbic acid biosynthetic process
A3L10_RS03635	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L10_RS03650	COG1757	Na H antiporter
A3L10_RS03655	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L10_RS03670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L10_RS03675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L10_RS03675	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L10_RS03710	COG0438	transferase activity, transferring glycosyl groups
A3L10_RS03715	COG3842	ATPase activity
A3L10_RS03720	COG3833	ABC-type maltose transport systems, permease component
A3L10_RS03725	COG1175	transmembrane transport
A3L10_RS03745	COG1554	hydrolase, family 65, central catalytic
A3L10_RS03750	COG0010	Belongs to the arginase family
A3L10_RS03770	COG0475	glutathione-regulated potassium exporter activity
A3L10_RS03795	COG1085	galactose-1-phosphate uridylyltransferase
A3L10_RS03800	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L10_RS03880	COG0252	asparaginase activity
A3L10_RS03885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L10_RS03905	COG2894	cell division
A3L10_RS03910	COG1063	alcohol dehydrogenase
A3L10_RS03925	COG0101	tRNA pseudouridine synthase activity
A3L10_RS03930	COG0556	nucleotide-excision repair
A3L10_RS03940	COG1131	(ABC) transporter
A3L10_RS03960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L10_RS03965	COG0628	permease
A3L10_RS04010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L10_RS04025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L10_RS04065	COG1122	ATPase activity
A3L10_RS04070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L10_RS04075	COG0024	Methionine aminopeptidase
A3L10_RS04085	COG0517	IMP dehydrogenase activity
A3L10_RS04085	COG0516	GMP reductase activity
A3L10_RS04105	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L10_RS04110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L10_RS04125	COG0504	CTP synthase activity
A3L10_RS04155	COG1473	amidohydrolase
A3L10_RS04160	COG2153	protein acetylation
A3L10_RS04165	COG0546	phosphoglycolate phosphatase activity
A3L10_RS04170	COG0585	pseudouridine synthase activity
A3L10_RS04185	COG0017	Asparaginyl-tRNA synthetase
A3L10_RS04195	COG1418	mRNA catabolic process
A3L10_RS04210	COG0546	phosphoglycolate phosphatase activity
A3L10_RS04220	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L10_RS04245	COG1110	DNA topoisomerase II activity
A3L10_RS04295	COG0644	oxidoreductase
A3L10_RS04300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L10_RS04315	COG1458	PINc domain ribonuclease
A3L10_RS04335	COG2358	TRAP transporter, solute receptor (TAXI family
A3L10_RS04360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L10_RS04365	COG0081	regulation of translation
A3L10_RS04390	COG0717	Belongs to the dCTP deaminase family
A3L10_RS04415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L10_RS04420	COG0058	SHG alpha-glucan phosphorylase activity
A3L10_RS04425	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3L10_RS04440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L10_RS04460	COG2271	Major facilitator Superfamily
A3L10_RS04465	COG2814	Major facilitator Superfamily
A3L10_RS04470	COG0584	glycerophosphoryl diester phosphodiesterase
A3L10_RS04475	COG0584	glycerophosphoryl diester phosphodiesterase
A3L10_RS04530	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L10_RS04555	COG0085	RNA polymerase activity
A3L10_RS04560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L10_RS04565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L10_RS04585	COG0049	tRNA binding
A3L10_RS04630	COG0436	Aminotransferase
A3L10_RS04655	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L10_RS04680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L10_RS04690	COG0662	Cupin 2, conserved barrel domain protein
A3L10_RS04690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A3L10_RS04710	COG2140	Oxalate decarboxylase
A3L10_RS04745	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L10_RS04750	COG4139	cobalamin transport
A3L10_RS04780	COG1131	(ABC) transporter
A3L10_RS04800	COG0798	PFAM Bile acid sodium symporter
A3L10_RS04840	COG0719	Fe-S assembly protein
A3L10_RS04845	COG1137	ATPase activity
A3L10_RS04870	COG0535	radical SAM domain protein
A3L10_RS04885	COG0489	protein tyrosine kinase activity
A3L10_RS04900	COG0746	molybdenum cofactor guanylyltransferase activity
A3L10_RS04905	COG0298	carbon dioxide binding
A3L10_RS04910	COG0409	Hydrogenase expression formation protein
A3L10_RS04915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L10_RS04930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L10_RS04950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L10_RS04950	COG0731	radical SAM domain protein
A3L10_RS04965	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L10_RS04980	COG1404	Belongs to the peptidase S8 family
A3L10_RS05000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L10_RS05000	COG0574	Belongs to the PEP-utilizing enzyme family
A3L10_RS05005	COG0534	Mate efflux family protein
A3L10_RS05010	COG0534	Mate efflux family protein
A3L10_RS05015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L10_RS05025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3L10_RS05040	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L10_RS05045	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L10_RS05060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L10_RS05065	COG0733	neurotransmitter:sodium symporter activity
A3L10_RS05075	COG0347	Belongs to the P(II) protein family
A3L10_RS05080	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L10_RS05095	COG0864	Transcriptional regulator
A3L10_RS05130	COG0006	proline dipeptidase activity
A3L10_RS05135	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A3L10_RS05145	COG0495	leucyl-tRNA aminoacylation
A3L10_RS05150	COG0477	Major facilitator Superfamily
A3L10_RS05155	COG0142	geranyltranstransferase activity
A3L10_RS05160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L10_RS05165	COG1304	FMN binding
A3L10_RS05170	COG2414	aldehyde ferredoxin oxidoreductase
A3L10_RS05175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L10_RS05185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L10_RS05200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L10_RS05215	COG1355	regulation of microtubule-based process
A3L10_RS05220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L10_RS05225	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L10_RS05240	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L10_RS05245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L10_RS05265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L10_RS05280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L10_RS05290	COG1522	sequence-specific DNA binding
A3L10_RS05330	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L10_RS05355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L10_RS05360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L10_RS05375	COG0202	RNA polymerase activity
A3L10_RS05385	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L10_RS05390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L10_RS05400	COG2813	Specifically methylates the guanine in position
A3L10_RS05410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L10_RS05425	COG1102	Psort location Cytoplasmic, score
A3L10_RS05450	COG0200	Binds to the 23S rRNA
A3L10_RS05455	COG1841	ribosomal large subunit assembly
A3L10_RS05460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L10_RS05465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L10_RS05485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L10_RS05505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L10_RS05510	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L10_RS05515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L10_RS05530	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L10_RS05535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L10_RS05540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A3L10_RS05545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L10_RS05550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L10_RS05555	COG0089	rRNA binding
A3L10_RS05560	COG0088	Forms part of the polypeptide exit tunnel
A3L10_RS05565	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L10_RS05595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L10_RS05610	COG0017	Asparaginyl-tRNA synthetase
A3L10_RS05615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L10_RS05640	COG0543	2 iron, 2 sulfur cluster binding
A3L10_RS05650	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A3L10_RS05690	COG0430	RNA-3'-phosphate cyclase activity
A3L10_RS05725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L10_RS05735	COG5016	pyruvate
A3L10_RS05735	COG0511	ligase activity, forming carbon-carbon bonds
A3L10_RS05740	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L10_RS05745	COG0517	IMP dehydrogenase activity
A3L10_RS05745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L10_RS05750	COG0460	homoserine dehydrogenase
A3L10_RS05780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3L10_RS05785	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L10_RS05800	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L10_RS05860	COG1335	isochorismatase
A3L10_RS05870	COG2050	protein possibly involved in aromatic compounds catabolism
A3L10_RS05870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L10_RS05875	COG1695	Transcriptional regulator
A3L10_RS05895	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L10_RS05945	COG0417	DNA replication proofreading
A3L10_RS05955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L10_RS05955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L10_RS05965	COG2078	PFAM AMMECR1 domain protein
A3L10_RS05970	COG0011	TIGRFAM Protein of
A3L10_RS05995	COG1177	transmembrane transport
A3L10_RS06010	COG2252	PERMEase
A3L10_RS06045	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L10_RS06050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L10_RS06060	COG3842	ATPase activity
A3L10_RS06070	COG0725	ABC transporter, periplasmic molybdate-binding protein
A3L10_RS06085	COG1160	GTP binding
A3L10_RS06090	COG0432	Pfam Uncharacterised protein family UPF0047
A3L10_RS06120	COG1832	CoA-binding protein
A3L10_RS06150	COG2379	hydroxypyruvate reductase
A3L10_RS06160	COG3842	ATPase activity
A3L10_RS06190	COG0463	Glycosyl transferase, family 2
A3L10_RS06235	COG1850	ribulose-bisphosphate carboxylase activity
A3L10_RS06280	COG1131	(ABC) transporter
A3L10_RS06295	COG0531	amino acid
A3L10_RS06305	COG1213	nucleotidyl transferase
A3L10_RS06305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L10_RS06310	COG3842	ATPase activity
A3L10_RS06315	COG0395	ABC-type sugar transport system, permease component
A3L10_RS06320	COG1175	transmembrane transport
A3L10_RS06340	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L10_RS06350	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L10_RS06350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L10_RS06360	COG1192	Involved in chromosome partitioning
A3L10_RS06365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L10_RS06370	COG0864	Transcriptional regulator
A3L10_RS06380	COG0436	Aminotransferase
A3L10_RS06385	COG2119	membrane
A3L10_RS06425	COG1476	TRANSCRIPTIONal
A3L10_RS06430	COG1131	(ABC) transporter
A3L10_RS06480	COG0543	2 iron, 2 sulfur cluster binding
A3L10_RS06485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L10_RS06485	COG0493	'glutamate synthase
A3L10_RS06495	COG0509	glycine decarboxylation via glycine cleavage system
A3L10_RS06500	COG1863	multisubunit Na H antiporter MnhE subunit
A3L10_RS06505	COG2212	antiporter activity
A3L10_RS06510	COG1320	monovalent cation:proton antiporter activity
A3L10_RS06535	COG0651	ATP synthesis coupled electron transport
A3L10_RS06540	COG0440	acetolactate synthase activity
A3L10_RS06555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L10_RS06575	COG0438	transferase activity, transferring glycosyl groups
A3L10_RS06605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L10_RS06610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L10_RS06675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L10_RS06695	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L10_RS06700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L10_RS06705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L10_RS06715	COG1765	OsmC-like protein
A3L10_RS06720	COG2095	MarC family integral membrane protein
A3L10_RS06755	COG0693	protein deglycase activity
A3L10_RS06760	COG1522	sequence-specific DNA binding
A3L10_RS06765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L10_RS06790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L10_RS06805	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L10_RS06820	COG2723	6-phospho-beta-galactosidase activity
A3L10_RS06860	COG0528	UMP kinase activity
A3L10_RS06865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L10_RS06895	COG0167	dihydroorotate dehydrogenase activity
A3L10_RS06910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L10_RS06930	COG2414	aldehyde ferredoxin oxidoreductase
A3L10_RS06950	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L10_RS06955	COG1141	Ferredoxin
A3L10_RS06975	COG1028	Short-chain dehydrogenase reductase Sdr
A3L10_RS06990	COG0493	'glutamate synthase
A3L10_RS06995	COG0543	2 iron, 2 sulfur cluster binding
A3L10_RS07030	COG0501	Belongs to the peptidase M48B family
A3L10_RS07035	COG2131	deaminase
A3L10_RS07045	COG0546	phosphoglycolate phosphatase activity
A3L10_RS07050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3L10_RS07060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L10_RS07065	COG2271	Major facilitator Superfamily
A3L10_RS07080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L10_RS07090	COG1446	asparaginase
A3L10_RS07110	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L10_RS07160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3L10_RS07190	COG1530	ribonuclease E activity
A3L10_RS07200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L10_RS07210	COG2255	four-way junction helicase activity
A3L10_RS07215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3L10_RS07220	COG0156	8-amino-7-oxononanoate synthase activity
A3L10_RS07235	COG1214	PFAM Peptidase M22, glycoprotease
A3L10_RS07235	COG0456	acetyltransferase
A3L10_RS07240	COG0433	COG0433 Predicted ATPase
A3L10_RS07250	COG0419	ATPase involved in DNA repair
A3L10_RS07250	COG0419	ATPase involved in DNA repair
A3L10_RS07265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A3L10_RS07270	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L10_RS07275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A3L10_RS07285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L10_RS07290	COG2078	PFAM AMMECR1 domain protein
A3L10_RS07290	COG3885	ferrous iron binding
A3L10_RS07300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L10_RS07305	COG0442	prolyl-tRNA aminoacylation
A3L10_RS07315	COG0454	-acetyltransferase
A3L10_RS07325	COG0432	Pfam Uncharacterised protein family UPF0047
A3L10_RS07340	COG0540	Belongs to the ATCase OTCase family
A3L10_RS07345	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L10_RS07360	COG0237	dephospho-CoA kinase activity
A3L10_RS07370	COG1988	membrane-bound metal-dependent
A3L10_RS07375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L10_RS07400	COG0434	BtpA family
A3L10_RS07415	COG0714	Associated with various cellular activities
A3L10_RS07445	COG0312	modulator of DNA gyrase
A3L10_RS07455	COG0312	modulator of DNA gyrase
A3L10_RS07460	COG1846	Transcriptional regulator
A3L10_RS07515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3L10_RS07530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L10_RS07565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L10_RS07580	COG0306	phosphate transporter
A3L10_RS07595	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS07600	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS07610	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS07615	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L10_RS07630	COG0493	'glutamate synthase
A3L10_RS07630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A3L10_RS07640	COG1151	hydroxylamine reductase activity
A3L10_RS07655	COG0489	protein tyrosine kinase activity
A3L10_RS07680	COG1131	(ABC) transporter
A3L10_RS07705	COG1254	Belongs to the acylphosphatase family
A3L10_RS07715	COG1628	Protein of unknown function DUF99
A3L10_RS07735	COG0778	Nitroreductase
A3L10_RS07760	COG4608	Belongs to the ABC transporter superfamily
A3L10_RS07765	COG0444	Belongs to the ABC transporter superfamily
A3L10_RS07770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L10_RS07775	COG0601	transmembrane transport
A3L10_RS07780	COG0747	negative chemotaxis
A3L10_RS07785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A3L10_RS07790	COG0697	spore germination
A3L10_RS07805	COG1980	fructose-bisphosphate aldolase activity
A3L10_RS07835	COG1233	COG1233 Phytoene dehydrogenase and related
A3L10_RS07905	COG1522	sequence-specific DNA binding
A3L10_RS07910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L10_RS07920	COG2894	cell division
A3L10_RS07925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3L10_RS07935	COG1793	dna ligase
A3L10_RS07955	COG1757	Na H antiporter
A3L10_RS07960	COG1573	uracil-dna glycosylase
A3L10_RS07970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L10_RS07985	COG1380	Effector of murein hydrolase LrgA
A3L10_RS07990	COG1346	cytolysis
A3L10_RS08010	COG0235	Class ii aldolase
A3L10_RS08020	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A3L10_RS08065	COG0095	Lipoate-protein ligase
A3L10_RS08095	COG1506	peptidase
A3L10_RS08095	COG4946	Tricorn protease homolog
A3L10_RS08095	COG0823	Involved in the tonB-independent uptake of proteins
A3L10_RS08120	COG0306	phosphate transporter
A3L10_RS08150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L10_RS08165	COG1863	multisubunit Na H antiporter MnhE subunit
A3L10_RS08170	COG2212	antiporter activity
A3L10_RS08175	COG1320	monovalent cation:proton antiporter activity
A3L10_RS08200	COG0651	ATP synthesis coupled electron transport
A3L10_RS08210	COG3260	NADH ubiquinone oxidoreductase 20
A3L10_RS08215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L10_RS08225	COG0650	Formate hydrogenlyase subunit 4
A3L10_RS08230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L10_RS08240	COG2212	antiporter activity
A3L10_RS08245	COG1320	monovalent cation:proton antiporter activity
A3L10_RS08260	COG2111	Na H antiporter
A3L10_RS08265	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L10_RS08270	COG0651	ATP synthesis coupled electron transport
A3L10_RS08280	COG3260	NADH ubiquinone oxidoreductase 20
A3L10_RS08285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L10_RS08300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3L10_RS08340	COG0492	ferredoxin-NADP+ reductase activity
A3L10_RS08345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L10_RS08360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A3L10_RS08375	COG0148	phosphopyruvate hydratase activity
A3L10_RS08390	COG1522	sequence-specific DNA binding
A3L10_RS08395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3L10_RS08415	COG0314	molybdopterin synthase activity
A3L10_RS08425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L10_RS08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L10_RS08465	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L10_RS08480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L10_RS08490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L10_RS08500	COG1042	CoA-binding domain protein
A3L10_RS08500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS08500	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L10_RS08555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L10_RS08585	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L10_RS08590	COG0402	S-adenosylhomocysteine deaminase activity
A3L10_RS08600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L10_RS08600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L10_RS08610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L10_RS08610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L10_RS08620	COG0640	Transcriptional regulator
A3L10_RS08630	COG0640	Transcriptional regulator
A3L10_RS08635	COG1042	CoA-binding domain protein
A3L10_RS08635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L10_RS08635	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L10_RS08670	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L10_RS08695	COG0116	Belongs to the methyltransferase superfamily
A3L10_RS08700	COG1160	GTP binding
A3L10_RS08735	COG1047	Peptidyl-prolyl cis-trans
A3L10_RS08755	COG0714	Associated with various cellular activities
A3L10_RS08775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L10_RS08790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L10_RS08795	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A3L10_RS08820	COG0037	tRNA processing
A3L10_RS08830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A3L10_RS08865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A3L10_RS08870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L10_RS08875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A3L10_RS08880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A3L10_RS08905	COG2723	6-phospho-beta-galactosidase activity
A3L10_RS08910	COG4166	transmembrane transport
A3L10_RS08915	COG0601	transmembrane transport
A3L10_RS08930	COG4608	Belongs to the ABC transporter superfamily
A3L10_RS08935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L10_RS08950	COG0076	glutamate decarboxylase activity
A3L10_RS08975	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L10_RS08985	COG0037	tRNA processing
A3L10_RS09000	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L10_RS09010	COG0475	glutathione-regulated potassium exporter activity
A3L10_RS09015	COG0475	glutathione-regulated potassium exporter activity
A3L10_RS09035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L10_RS09040	COG1115	amino acid carrier protein
A3L10_RS09075	COG0681	Belongs to the peptidase S26 family
A3L10_RS09085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L10_RS09095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L10_RS09135	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L10_RS09150	COG0569	domain protein
A3L10_RS09160	COG1269	ATP hydrolysis coupled proton transport
A3L10_RS09170	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L10_RS09180	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L10_RS09185	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L10_RS09200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L10_RS09215	COG1606	tRNA processing
A3L10_RS09255	COG0601	transmembrane transport
A3L10_RS09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L10_RS09265	COG0444	Belongs to the ABC transporter superfamily
A3L10_RS09270	COG4608	Belongs to the ABC transporter superfamily
A3L10_RS09290	COG0174	glutamine synthetase
A3L10_RS09330	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L10_RS09350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L10_RS09355	COG0095	Lipoate-protein ligase
A3L10_RS09360	COG3199	ATP-NAD kinase
A3L10_RS09365	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3L10_RS09370	COG0508	dehydrogenase complex catalyzes the overall conversion of
A3L10_RS09375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3L10_RS09380	COG0022	dehydrogenase e1 component
A3L10_RS09395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A3L10_RS09400	COG0022	dehydrogenase e1 component
A3L10_RS09420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L10_RS09430	COG1297	OPT oligopeptide transporter protein
A3L10_RS09435	COG1234	tRNA 3'-trailer cleavage
A3L10_RS09440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L10_RS09450	COG3842	ATPase activity
A3L10_RS09460	COG3833	ABC-type maltose transport systems, permease component
A3L10_RS09465	COG1175	transmembrane transport
A3L10_RS09475	COG0366	Alpha amylase catalytic
A3L10_RS09480	COG1378	Sugar-specific transcriptional regulator TrmB
A3L10_RS09485	COG0297	glycogen (starch) synthase activity
A3L10_RS09495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A3L10_RS09535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L10_RS09540	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A3L10_RS09550	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L10_RS09560	COG0647	UMP catabolic process
A3L10_RS09600	COG0714	Associated with various cellular activities
A3L10_RS09640	COG2244	polysaccharide biosynthetic process
A3L10_RS09670	COG0730	response to heat
A3L10_RS09675	COG0529	Catalyzes the synthesis of activated sulfate
A3L10_RS09690	COG2046	Belongs to the sulfate adenylyltransferase family
A3L10_RS09785	COG0517	IMP dehydrogenase activity
A3L10_RS09785	COG0516	GMP reductase activity
A3L10_RS09790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L10_RS09795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L10_RS09805	COG3383	formate dehydrogenase (NAD+) activity
A3L10_RS09810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L10_RS09815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L10_RS09820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L10_RS09825	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L10_RS09830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L10_RS09835	COG0151	Belongs to the GarS family
A3L10_RS09850	COG0047	phosphoribosylformylglycinamidine synthase activity
A3L10_RS09855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L10_RS09865	COG0519	Catalyzes the synthesis of GMP from XMP
A3L10_RS09865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L10_RS09870	COG0519	Catalyzes the synthesis of GMP from XMP
A3L10_RS09870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L10_RS09935	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L10_RS10030	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L10_RS10040	COG2234	aminopeptidase activity
A3L10_RS10095	COG0393	Putative heavy-metal-binding
A3L10_RS10120	COG2264	protein methyltransferase activity
A3L10_RS10135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L10_RS10135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L10_RS10140	COG0668	transmembrane transport
A3L10_RS10205	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L10_RS10210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L10_RS10215	COG0552	protein localization to endoplasmic reticulum
A3L10_RS10220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate