locus-tag	class	description
GQS_RS00050	COG0402	S-adenosylhomocysteine deaminase activity
GQS_RS00070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_RS00095	COG2815	serine threonine protein kinase
GQS_RS00095	COG0515	serine threonine protein kinase
GQS_RS00110	COG0631	protein serine/threonine phosphatase activity
GQS_RS00115	COG2815	serine threonine protein kinase
GQS_RS00115	COG0515	serine threonine protein kinase
GQS_RS00125	COG0515	serine threonine protein kinase
GQS_RS00125	COG2815	serine threonine protein kinase
GQS_RS00130	COG2815	serine threonine protein kinase
GQS_RS00130	COG0515	serine threonine protein kinase
GQS_RS00170	COG0175	sulfate reduction
GQS_RS00210	COG0105	UTP biosynthetic process
GQS_RS00220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GQS_RS00225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_RS00230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS_RS00255	COG0419	ATPase involved in DNA repair
GQS_RS00255	COG0419	ATPase involved in DNA repair
GQS_RS00285	COG0084	hydrolase, TatD family'
GQS_RS00300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS_RS00305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS_RS00310	COG1201	RNA secondary structure unwinding
GQS_RS00320	COG0477	Major facilitator Superfamily
GQS_RS00335	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_RS00360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GQS_RS00370	COG1342	Belongs to the UPF0251 family
GQS_RS00465	COG0489	protein tyrosine kinase activity
GQS_RS00490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GQS_RS00505	COG2267	carboxylic ester hydrolase activity
GQS_RS00515	COG1830	Aldolase
GQS_RS00535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_RS00555	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQS_RS00560	COG1518	maintenance of DNA repeat elements
GQS_RS00585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GQS_RS00665	COG2033	superoxide reductase activity
GQS_RS00670	COG1773	rubredoxin
GQS_RS00675	COG1592	Rubrerythrin
GQS_RS00690	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GQS_RS00695	COG0640	Transcriptional regulator
GQS_RS00700	COG2217	Heavy metal translocating P-type atpase
GQS_RS00705	COG0456	acetyltransferase
GQS_RS00710	COG2217	Heavy metal translocating P-type atpase
GQS_RS00730	COG2226	methyltransferase
GQS_RS00750	COG0450	alkyl hydroperoxide reductase
GQS_RS00755	COG0243	molybdopterin cofactor binding
GQS_RS00805	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GQS_RS00860	COG0477	Major facilitator Superfamily
GQS_RS00865	COG0312	modulator of DNA gyrase
GQS_RS00890	COG1794	racemase activity, acting on amino acids and derivatives
GQS_RS00900	COG0668	transmembrane transport
GQS_RS00910	COG1993	acr, cog1993
GQS_RS00915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GQS_RS00935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GQS_RS00945	COG0563	adenylate kinase activity
GQS_RS00960	COG0011	TIGRFAM Protein of
GQS_RS00965	COG2226	methyltransferase
GQS_RS00980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GQS_RS00990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_RS01000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GQS_RS01010	COG1121	(ABC) transporter
GQS_RS01050	COG1401	restriction endodeoxyribonuclease activity
GQS_RS01065	COG1469	GTP cyclohydrolase I activity
GQS_RS01080	COG1078	dGTPase activity
GQS_RS01085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GQS_RS01095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS_RS01100	COG0051	transcription antitermination factor activity, RNA binding
GQS_RS01115	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GQS_RS01135	COG0732	type I restriction modification DNA specificity domain
GQS_RS01150	COG2414	aldehyde ferredoxin oxidoreductase
GQS_RS01155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GQS_RS01180	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
GQS_RS01195	COG0517	IMP dehydrogenase activity
GQS_RS01195	COG0617	tRNA 3'-terminal CCA addition
GQS_RS01195	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GQS_RS01220	COG1121	(ABC) transporter
GQS_RS01225	COG1111	helicase
GQS_RS01225	COG1205	dead DEAH box helicase
GQS_RS01230	COG1739	Uncharacterized protein family UPF0029
GQS_RS01260	COG1216	Glycosyl transferase, family 2
GQS_RS01275	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQS_RS01275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_RS01305	COG0315	cyclic pyranopterin monophosphate synthase activity
GQS_RS01315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GQS_RS01325	COG0459	protein refolding
GQS_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
GQS_RS01345	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GQS_RS01350	COG0277	FAD linked oxidase domain protein
GQS_RS01360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GQS_RS01395	COG2819	hydrolase of the alpha beta superfamily
GQS_RS01410	COG1078	dGTPase activity
GQS_RS01435	COG0303	'Molybdopterin
GQS_RS01465	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GQS_RS01475	COG0746	molybdenum cofactor guanylyltransferase activity
GQS_RS01480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GQS_RS01490	COG1573	uracil-dna glycosylase
GQS_RS01495	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GQS_RS01500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GQS_RS01515	COG0714	Associated with various cellular activities
GQS_RS01530	COG2226	methyltransferase
GQS_RS01535	COG0525	valine-tRNA ligase activity
GQS_RS01550	COG1525	nuclease
GQS_RS01555	COG2264	protein methyltransferase activity
GQS_RS01570	COG0312	modulator of DNA gyrase
GQS_RS01580	COG1794	racemase activity, acting on amino acids and derivatives
GQS_RS01585	COG0598	Magnesium transport protein CorA
GQS_RS01590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GQS_RS01600	COG0012	GTP binding
GQS_RS01610	COG1522	sequence-specific DNA binding
GQS_RS01615	COG0163	prenyltransferase activity
GQS_RS01635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GQS_RS01645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GQS_RS01645	COG1918	ferrous iron import across plasma membrane
GQS_RS01660	COG0482	sulfurtransferase activity
GQS_RS01685	COG0006	proline dipeptidase activity
GQS_RS01700	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
GQS_RS01710	COG0534	Mate efflux family protein
GQS_RS01725	COG0423	glycine-tRNA ligase activity
GQS_RS01735	COG1872	DUF167
GQS_RS01750	COG1546	Belongs to the CinA family
GQS_RS01750	COG1058	Belongs to the CinA family
GQS_RS01765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_RS01775	COG2096	Adenosyltransferase
GQS_RS01785	COG2814	Major facilitator Superfamily
GQS_RS01810	COG2409	Drug exporters of the RND superfamily
GQS_RS01820	COG1363	Peptidase, m42
GQS_RS01905	COG1215	transferase activity, transferring glycosyl groups
GQS_RS01930	COG1505	serine-type exopeptidase activity
GQS_RS01940	COG4145	pantothenate transmembrane transporter activity
GQS_RS01955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS_RS01965	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
GQS_RS01970	COG0351	phosphomethylpyrimidine kinase
GQS_RS01970	COG1992	Thiamine-phosphate synthase
GQS_RS02000	COG0215	cysteine-tRNA ligase activity
GQS_RS02025	COG1079	Belongs to the binding-protein-dependent transport system permease family
GQS_RS02030	COG4603	Belongs to the binding-protein-dependent transport system permease family
GQS_RS02035	COG3845	ABC transporter
GQS_RS02040	COG1744	ABC transporter substrate-binding protein PnrA-like
GQS_RS02060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GQS_RS02075	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_RS02075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQS_RS02080	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_RS02090	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GQS_RS02090	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_RS02095	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_RS02120	COG0720	synthase
GQS_RS02150	COG0730	response to heat
GQS_RS02160	COG0730	response to heat
GQS_RS02180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GQS_RS02185	COG0442	prolyl-tRNA aminoacylation
GQS_RS02195	COG2192	nodulation
GQS_RS02210	COG0436	Aminotransferase
GQS_RS02220	COG0501	Belongs to the peptidase M48B family
GQS_RS02225	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GQS_RS02235	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
GQS_RS02245	COG1515	deoxyribonuclease V activity
GQS_RS02280	COG1476	TRANSCRIPTIONal
GQS_RS02285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GQS_RS02300	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GQS_RS02305	COG3259	Nickel-dependent hydrogenase
GQS_RS02315	COG0437	4 iron, 4 sulfur cluster binding
GQS_RS02330	COG2111	Na H antiporter
GQS_RS02330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_RS02340	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_RS02370	COG3260	NADH ubiquinone oxidoreductase 20
GQS_RS02375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS02380	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GQS_RS02380	COG3261	NADH dehydrogenase
GQS_RS02385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS_RS02390	COG0651	ATP synthesis coupled electron transport
GQS_RS02395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_RS02405	COG0243	molybdopterin cofactor binding
GQS_RS02425	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
GQS_RS02430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GQS_RS02450	COG0719	Fe-S assembly protein
GQS_RS02455	COG0396	ATPase activity
GQS_RS02485	COG1694	Mazg nucleotide pyrophosphohydrolase
GQS_RS02490	COG1522	sequence-specific DNA binding
GQS_RS02495	COG1836	PFAM Integral membrane protein DUF92
GQS_RS02500	COG0301	tRNA thio-modification
GQS_RS02500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GQS_RS02520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GQS_RS02595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GQS_RS02605	COG0018	arginyl-trna synthetase
GQS_RS02635	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GQS_RS02655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_RS02665	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_RS02670	COG2212	antiporter activity
GQS_RS02675	COG1320	monovalent cation:proton antiporter activity
GQS_RS02685	COG2111	Na H antiporter
GQS_RS02685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GQS_RS02690	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_RS02695	COG0651	ATP synthesis coupled electron transport
GQS_RS02700	COG0651	ATP synthesis coupled electron transport
GQS_RS02710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS02715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS02715	COG0649	NAD binding
GQS_RS02715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS02720	COG0649	NAD binding
GQS_RS02750	COG1522	sequence-specific DNA binding
GQS_RS02770	COG1151	hydroxylamine reductase activity
GQS_RS02805	COG1881	PFAM PEBP family protein
GQS_RS02835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_RS02840	COG0602	queuosine metabolic process
GQS_RS02845	COG0640	Transcriptional regulator
GQS_RS02910	COG0359	binds to the 23S rRNA
GQS_RS02910	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GQS_RS02930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_RS02930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_RS02955	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GQS_RS02970	COG1757	Na H antiporter
GQS_RS02980	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GQS_RS02990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GQS_RS03030	COG0010	Belongs to the arginase family
GQS_RS03045	COG0475	glutathione-regulated potassium exporter activity
GQS_RS03065	COG1085	galactose-1-phosphate uridylyltransferase
GQS_RS03070	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GQS_RS03080	COG0438	transferase activity, transferring glycosyl groups
GQS_RS03150	COG0252	asparaginase activity
GQS_RS03185	COG2894	cell division
GQS_RS03190	COG1063	alcohol dehydrogenase
GQS_RS03205	COG0101	tRNA pseudouridine synthase activity
GQS_RS03210	COG0556	nucleotide-excision repair
GQS_RS03220	COG1131	(ABC) transporter
GQS_RS03245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GQS_RS03250	COG0628	permease
GQS_RS03300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GQS_RS03315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GQS_RS03360	COG1122	ATPase activity
GQS_RS03365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GQS_RS03370	COG0024	Methionine aminopeptidase
GQS_RS03380	COG0516	GMP reductase activity
GQS_RS03380	COG0517	IMP dehydrogenase activity
GQS_RS03390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GQS_RS03405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_RS03425	COG0504	CTP synthase activity
GQS_RS03455	COG1473	amidohydrolase
GQS_RS03470	COG0585	pseudouridine synthase activity
GQS_RS03485	COG0017	Asparaginyl-tRNA synthetase
GQS_RS03495	COG1418	mRNA catabolic process
GQS_RS03510	COG0546	phosphoglycolate phosphatase activity
GQS_RS03520	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GQS_RS03560	COG1110	DNA topoisomerase II activity
GQS_RS03620	COG1518	maintenance of DNA repeat elements
GQS_RS03630	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GQS_RS03655	COG0644	oxidoreductase
GQS_RS03660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GQS_RS03675	COG1458	PINc domain ribonuclease
GQS_RS03695	COG2358	TRAP transporter, solute receptor (TAXI family
GQS_RS03705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS_RS03720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GQS_RS03725	COG0081	regulation of translation
GQS_RS03745	COG0717	Belongs to the dCTP deaminase family
GQS_RS03770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GQS_RS03780	COG0058	SHG alpha-glucan phosphorylase activity
GQS_RS03785	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GQS_RS03800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GQS_RS03830	COG2814	Major facilitator Superfamily
GQS_RS03835	COG0584	glycerophosphoryl diester phosphodiesterase
GQS_RS03840	COG0584	glycerophosphoryl diester phosphodiesterase
GQS_RS03850	COG0579	oxidoreductase
GQS_RS03910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_RS03915	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_RS03940	COG0085	RNA polymerase activity
GQS_RS03945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS_RS03950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GQS_RS03970	COG0049	tRNA binding
GQS_RS03985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GQS_RS04015	COG0436	Aminotransferase
GQS_RS04040	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_RS04075	COG0662	Cupin 2, conserved barrel domain protein
GQS_RS04075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GQS_RS04085	COG2140	Oxalate decarboxylase
GQS_RS04135	COG0798	PFAM Bile acid sodium symporter
GQS_RS04175	COG0719	Fe-S assembly protein
GQS_RS04180	COG1137	ATPase activity
GQS_RS04205	COG2414	aldehyde ferredoxin oxidoreductase
GQS_RS04215	COG0489	protein tyrosine kinase activity
GQS_RS04230	COG0298	carbon dioxide binding
GQS_RS04235	COG0409	Hydrogenase expression formation protein
GQS_RS04240	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GQS_RS04265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GQS_RS04275	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS_RS04285	COG0731	radical SAM domain protein
GQS_RS04285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_RS04300	COG0446	pyridine nucleotide-disulphide oxidoreductase
GQS_RS04315	COG1404	Belongs to the peptidase S8 family
GQS_RS04340	COG0574	Belongs to the PEP-utilizing enzyme family
GQS_RS04340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GQS_RS04345	COG0534	Mate efflux family protein
GQS_RS04355	COG0534	Mate efflux family protein
GQS_RS04360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GQS_RS04370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GQS_RS04385	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQS_RS04390	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GQS_RS04405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GQS_RS04410	COG0733	neurotransmitter:sodium symporter activity
GQS_RS04420	COG0347	Belongs to the P(II) protein family
GQS_RS04425	COG1543	Belongs to the glycosyl hydrolase 57 family
GQS_RS04440	COG0864	Transcriptional regulator
GQS_RS04495	COG0006	proline dipeptidase activity
GQS_RS04505	COG0495	leucyl-tRNA aminoacylation
GQS_RS04510	COG0477	Major facilitator Superfamily
GQS_RS04515	COG0142	geranyltranstransferase activity
GQS_RS04525	COG1304	FMN binding
GQS_RS04530	COG2414	aldehyde ferredoxin oxidoreductase
GQS_RS04535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_RS04540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GQS_RS04560	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQS_RS04570	COG1355	regulation of microtubule-based process
GQS_RS04575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GQS_RS04580	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GQS_RS04595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GQS_RS04600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQS_RS04615	COG1160	GTP binding
GQS_RS04620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GQS_RS04635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GQS_RS04645	COG1522	sequence-specific DNA binding
GQS_RS04675	COG0052	Belongs to the universal ribosomal protein uS2 family
GQS_RS04700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GQS_RS04705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GQS_RS04720	COG0202	RNA polymerase activity
GQS_RS04725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GQS_RS04730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GQS_RS04735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GQS_RS04750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GQS_RS04765	COG1102	Psort location Cytoplasmic, score
GQS_RS04790	COG0200	Binds to the 23S rRNA
GQS_RS04795	COG1841	ribosomal large subunit assembly
GQS_RS04800	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GQS_RS04805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GQS_RS04820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GQS_RS04825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GQS_RS04835	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GQS_RS04845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GQS_RS04850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GQS_RS04855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GQS_RS04870	COG0255	Belongs to the universal ribosomal protein uL29 family
GQS_RS04875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GQS_RS04885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GQS_RS04890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GQS_RS04895	COG0089	rRNA binding
GQS_RS04900	COG0088	Forms part of the polypeptide exit tunnel
GQS_RS04905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GQS_RS04935	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GQS_RS04950	COG0017	Asparaginyl-tRNA synthetase
GQS_RS04955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GQS_RS04995	COG0543	2 iron, 2 sulfur cluster binding
GQS_RS05005	COG3259	Nickel-dependent hydrogenase
GQS_RS05030	COG0430	RNA-3'-phosphate cyclase activity
GQS_RS05065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GQS_RS05075	COG0511	ligase activity, forming carbon-carbon bonds
GQS_RS05075	COG5016	pyruvate
GQS_RS05080	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GQS_RS05085	COG0517	IMP dehydrogenase activity
GQS_RS05085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GQS_RS05120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GQS_RS05125	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_RS05205	COG1335	isochorismatase
GQS_RS05215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_RS05215	COG2050	protein possibly involved in aromatic compounds catabolism
GQS_RS05225	COG1695	Transcriptional regulator
GQS_RS05245	COG1185	polyribonucleotide nucleotidyltransferase activity
GQS_RS05285	COG0417	DNA replication proofreading
GQS_RS05295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GQS_RS05295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_RS05300	COG2078	PFAM AMMECR1 domain protein
GQS_RS05305	COG0011	TIGRFAM Protein of
GQS_RS05330	COG1178	ABC-type Fe3 transport system permease component
GQS_RS05335	COG3842	ATPase activity
GQS_RS05355	COG2252	PERMEase
GQS_RS05405	COG0109	protoheme IX farnesyltransferase activity
GQS_RS05415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GQS_RS05420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GQS_RS05445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GQS_RS05480	COG0668	transmembrane transport
GQS_RS05495	COG2264	protein methyltransferase activity
GQS_RS05515	COG0393	Putative heavy-metal-binding
GQS_RS05580	COG2234	aminopeptidase activity
GQS_RS05685	COG2264	protein methyltransferase activity
GQS_RS05750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS_RS05750	COG0519	Catalyzes the synthesis of GMP from XMP
GQS_RS05765	COG0519	Catalyzes the synthesis of GMP from XMP
GQS_RS05765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GQS_RS05775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GQS_RS05785	COG0047	phosphoribosylformylglycinamidine synthase activity
GQS_RS05800	COG0151	Belongs to the GarS family
GQS_RS05805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GQS_RS05810	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GQS_RS05815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GQS_RS05820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GQS_RS05825	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GQS_RS05840	COG3383	formate dehydrogenase (NAD+) activity
GQS_RS05845	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GQS_RS05850	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GQS_RS05860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GQS_RS05865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GQS_RS05875	COG0516	GMP reductase activity
GQS_RS05875	COG0517	IMP dehydrogenase activity
GQS_RS05905	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
GQS_RS05915	COG1120	ATPase activity
GQS_RS05920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS_RS05985	COG0438	transferase activity, transferring glycosyl groups
GQS_RS05985	COG0297	glycogen (starch) synthase activity
GQS_RS06020	COG1287	oligosaccharyl transferase activity
GQS_RS06055	COG0714	Associated with various cellular activities
GQS_RS06100	COG0438	transferase activity, transferring glycosyl groups
GQS_RS06110	COG0438	transferase activity, transferring glycosyl groups
GQS_RS06130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GQS_RS06135	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GQS_RS06145	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GQS_RS06220	COG0297	glycogen (starch) synthase activity
GQS_RS06225	COG1378	Sugar-specific transcriptional regulator TrmB
GQS_RS06240	COG1175	transmembrane transport
GQS_RS06245	COG3833	ABC-type maltose transport systems, permease component
GQS_RS06255	COG3842	ATPase activity
GQS_RS06265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS_RS06275	COG1234	tRNA 3'-trailer cleavage
GQS_RS06280	COG1297	OPT oligopeptide transporter protein
GQS_RS06290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GQS_RS06310	COG0022	dehydrogenase e1 component
GQS_RS06315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS_RS06330	COG0022	dehydrogenase e1 component
GQS_RS06335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GQS_RS06340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS_RS06345	COG0508	dehydrogenase complex catalyzes the overall conversion of
GQS_RS06350	COG3199	ATP-NAD kinase
GQS_RS06355	COG0095	Lipoate-protein ligase
GQS_RS06360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS_RS06380	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQS_RS06415	COG0174	glutamine synthetase
GQS_RS06435	COG4608	Belongs to the ABC transporter superfamily
GQS_RS06440	COG0444	Belongs to the ABC transporter superfamily
GQS_RS06445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS_RS06450	COG0601	transmembrane transport
GQS_RS06460	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GQS_RS06490	COG0482	sulfurtransferase activity
GQS_RS06495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_RS06505	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
GQS_RS06510	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GQS_RS06525	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
GQS_RS06535	COG1269	ATP hydrolysis coupled proton transport
GQS_RS06545	COG0569	domain protein
GQS_RS06550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS_RS06555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GQS_RS06560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GQS_RS06570	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GQS_RS06615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GQS_RS06635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_RS06705	COG0475	glutathione-regulated potassium exporter activity
GQS_RS06710	COG0475	glutathione-regulated potassium exporter activity
GQS_RS06715	COG0516	GMP reductase activity
GQS_RS06715	COG0517	IMP dehydrogenase activity
GQS_RS06720	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GQS_RS06730	COG0037	tRNA processing
GQS_RS06745	COG1449	Belongs to the glycosyl hydrolase 57 family
GQS_RS06770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GQS_RS06770	COG4651	solute:proton antiporter activity
GQS_RS06775	COG0076	glutamate decarboxylase activity
GQS_RS06790	COG2046	Belongs to the sulfate adenylyltransferase family
GQS_RS06805	COG0529	Catalyzes the synthesis of activated sulfate
GQS_RS06810	COG0730	response to heat
GQS_RS06820	COG3119	arylsulfatase activity
GQS_RS06845	COG3119	arylsulfatase activity
GQS_RS06850	COG1216	Glycosyl transferase, family 2
GQS_RS06850	COG0463	Glycosyl transferase, family 2
GQS_RS06855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GQS_RS06860	COG0037	tRNA processing
GQS_RS06895	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GQS_RS06900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GQS_RS06910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GQS_RS06930	COG0714	Associated with various cellular activities
GQS_RS06955	COG1047	Peptidyl-prolyl cis-trans
GQS_RS06990	COG1160	GTP binding
GQS_RS07005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GQS_RS07005	COG0116	Belongs to the methyltransferase superfamily
GQS_RS07025	COG0179	Fumarylacetoacetate (FAA) hydrolase
GQS_RS07075	COG1042	CoA-binding domain protein
GQS_RS07075	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_RS07075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_RS07080	COG0640	Transcriptional regulator
GQS_RS07105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GQS_RS07105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GQS_RS07110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GQS_RS07110	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GQS_RS07120	COG0402	S-adenosylhomocysteine deaminase activity
GQS_RS07130	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GQS_RS07175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GQS_RS07240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GQS_RS07250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GQS_RS07265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GQS_RS07265	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GQS_RS07305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GQS_RS07315	COG0314	molybdopterin synthase activity
GQS_RS07335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GQS_RS07340	COG1522	sequence-specific DNA binding
GQS_RS07365	COG0148	phosphopyruvate hydratase activity
GQS_RS07380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GQS_RS07395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GQS_RS07400	COG0492	ferredoxin-NADP+ reductase activity
GQS_RS07415	COG2255	four-way junction helicase activity
GQS_RS07445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GQS_RS07460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS07465	COG3260	NADH ubiquinone oxidoreductase 20
GQS_RS07475	COG0651	ATP synthesis coupled electron transport
GQS_RS07480	COG1006	Multisubunit Na H antiporter MnhC subunit
GQS_RS07485	COG2111	Na H antiporter
GQS_RS07500	COG1320	monovalent cation:proton antiporter activity
GQS_RS07505	COG2212	antiporter activity
GQS_RS07515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS07520	COG0650	Formate hydrogenlyase subunit 4
GQS_RS07530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GQS_RS07535	COG3260	NADH ubiquinone oxidoreductase 20
GQS_RS07545	COG0651	ATP synthesis coupled electron transport
GQS_RS07570	COG1320	monovalent cation:proton antiporter activity
GQS_RS07575	COG2212	antiporter activity
GQS_RS07580	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_RS07595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GQS_RS07625	COG0306	phosphate transporter
GQS_RS07670	COG0823	Involved in the tonB-independent uptake of proteins
GQS_RS07670	COG4946	Tricorn protease homolog
GQS_RS07670	COG1506	peptidase
GQS_RS07725	COG0681	Belongs to the peptidase S26 family
GQS_RS07730	COG0095	Lipoate-protein ligase
GQS_RS07770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GQS_RS07780	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GQS_RS07790	COG0235	Class ii aldolase
GQS_RS07820	COG1346	cytolysis
GQS_RS07825	COG1380	Effector of murein hydrolase LrgA
GQS_RS07840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_RS07850	COG1573	uracil-dna glycosylase
GQS_RS07855	COG1757	Na H antiporter
GQS_RS07875	COG1793	dna ligase
GQS_RS07885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GQS_RS07890	COG2894	cell division
GQS_RS07905	COG1522	sequence-specific DNA binding
GQS_RS07915	COG1980	fructose-bisphosphate aldolase activity
GQS_RS07925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS_RS08015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GQS_RS08035	COG1254	Belongs to the acylphosphatase family
GQS_RS08045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GQS_RS08070	COG0489	protein tyrosine kinase activity
GQS_RS08075	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS_RS08095	COG0746	molybdenum cofactor guanylyltransferase activity
GQS_RS08100	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_RS08105	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_RS08115	COG1013	pyruvate-flavodoxin oxidoreductase activity
GQS_RS08120	COG0674	pyruvate-flavodoxin oxidoreductase activity
GQS_RS08135	COG0306	phosphate transporter
GQS_RS08140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GQS_RS08170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GQS_RS08180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GQS_RS08185	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS_RS08185	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GQS_RS08240	COG0312	modulator of DNA gyrase
GQS_RS08280	COG0714	Associated with various cellular activities
GQS_RS08295	COG0434	BtpA family
GQS_RS08325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GQS_RS08330	COG1988	membrane-bound metal-dependent
GQS_RS08350	COG0237	dephospho-CoA kinase activity
GQS_RS08365	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GQS_RS08370	COG0540	Belongs to the ATCase OTCase family
GQS_RS08385	COG0432	Pfam Uncharacterised protein family UPF0047
GQS_RS08405	COG0667	Aldo Keto reductase
GQS_RS08420	COG0442	prolyl-tRNA aminoacylation
GQS_RS08425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GQS_RS08455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GQS_RS08460	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GQS_RS08465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GQS_RS08475	COG0456	acetyltransferase
GQS_RS08475	COG1214	PFAM Peptidase M22, glycoprotease
GQS_RS08490	COG0156	8-amino-7-oxononanoate synthase activity
GQS_RS08495	COG2255	four-way junction helicase activity
GQS_RS08525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GQS_RS08535	COG1530	ribonuclease E activity
GQS_RS08565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GQS_RS08605	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GQS_RS08625	COG1446	asparaginase
GQS_RS08635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GQS_RS08655	COG2814	Major facilitator Superfamily
GQS_RS08660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_RS08670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GQS_RS08685	COG2131	deaminase
GQS_RS08690	COG0501	Belongs to the peptidase M48B family
GQS_RS08725	COG0543	2 iron, 2 sulfur cluster binding
GQS_RS08730	COG0493	'glutamate synthase
GQS_RS08730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
GQS_RS08760	COG1141	Ferredoxin
GQS_RS08765	COG2151	metal-sulfur cluster biosynthetic enzyme
GQS_RS08785	COG1404	Belongs to the peptidase S8 family
GQS_RS08805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GQS_RS08810	COG0167	dihydroorotate dehydrogenase activity
GQS_RS08830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GQS_RS08835	COG0528	UMP kinase activity
GQS_RS08870	COG2723	6-phospho-beta-galactosidase activity
GQS_RS08885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GQS_RS08900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS_RS08935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GQS_RS08945	COG0693	protein deglycase activity
GQS_RS08985	COG2095	MarC family integral membrane protein
GQS_RS08990	COG1765	OsmC-like protein
GQS_RS09000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GQS_RS09005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GQS_RS09010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GQS_RS09030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GQS_RS09105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GQS_RS09110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GQS_RS09140	COG0438	transferase activity, transferring glycosyl groups
GQS_RS09160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GQS_RS09180	COG0440	acetolactate synthase activity
GQS_RS09185	COG0651	ATP synthesis coupled electron transport
GQS_RS09210	COG1320	monovalent cation:proton antiporter activity
GQS_RS09215	COG2212	antiporter activity
GQS_RS09220	COG1863	multisubunit Na H antiporter MnhE subunit
GQS_RS09225	COG0509	glycine decarboxylation via glycine cleavage system
GQS_RS09240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GQS_RS09240	COG0493	'glutamate synthase
GQS_RS09245	COG0543	2 iron, 2 sulfur cluster binding
GQS_RS09275	COG0747	negative chemotaxis
GQS_RS09280	COG0601	transmembrane transport
GQS_RS09285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS_RS09290	COG0444	Belongs to the ABC transporter superfamily
GQS_RS09295	COG4608	Belongs to the ABC transporter superfamily
GQS_RS09330	COG1131	(ABC) transporter
GQS_RS09340	COG1476	TRANSCRIPTIONal
GQS_RS09385	COG2119	membrane
GQS_RS09390	COG0436	Aminotransferase
GQS_RS09405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GQS_RS09410	COG1192	Involved in chromosome partitioning
GQS_RS09420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GQS_RS09420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GQS_RS09430	COG0284	orotidine-5'-phosphate decarboxylase activity
GQS_RS09460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQS_RS09460	COG1213	nucleotidyl transferase
GQS_RS09475	COG1131	(ABC) transporter
GQS_RS09520	COG1850	ribulose-bisphosphate carboxylase activity
GQS_RS09525	COG1435	thymidine kinase activity
GQS_RS09565	COG0463	Glycosyl transferase, family 2
GQS_RS09575	COG0673	inositol 2-dehydrogenase activity
GQS_RS09595	COG3842	ATPase activity
GQS_RS09605	COG2379	hydroxypyruvate reductase
GQS_RS09635	COG1832	CoA-binding protein
GQS_RS09660	COG1160	GTP binding
GQS_RS09680	COG0725	ABC transporter, periplasmic molybdate-binding protein
GQS_RS09685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GQS_RS09690	COG3842	ATPase activity
GQS_RS09700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GQS_RS09705	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GQS_RS09725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GQS_RS09730	COG0560	Phosphoserine phosphatase
GQS_RS09760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GQS_RS09790	COG1056	cytidyltransferase-related domain
GQS_RS09790	COG1051	belongs to the nudix hydrolase family
GQS_RS09830	COG2226	methyltransferase
GQS_RS09855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_RS09880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_RS09880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GQS_RS09890	COG0778	Nitroreductase
GQS_RS09895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GQS_RS09905	COG4608	Belongs to the ABC transporter superfamily
GQS_RS09910	COG0444	Belongs to the ABC transporter superfamily
GQS_RS09915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GQS_RS09920	COG0601	transmembrane transport
GQS_RS09925	COG0747	negative chemotaxis
GQS_RS09965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_RS09970	COG0071	Belongs to the small heat shock protein (HSP20) family
GQS_RS09980	COG1793	dna ligase
GQS_RS09980	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GQS_RS09985	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_RS09985	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_RS10070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_RS10070	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_RS10070	COG1042	CoA-binding domain protein
GQS_RS10090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GQS_RS10105	COG0303	'Molybdopterin
GQS_RS10110	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GQS_RS10130	COG0009	L-threonylcarbamoyladenylate synthase
GQS_RS10145	COG0367	asparagine synthase
GQS_RS10155	COG2894	cell division
GQS_RS10160	COG4956	integral membrane protein (PIN domain superfamily)
GQS_RS10175	COG0424	maF-like protein
GQS_RS10180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GQS_RS10185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_RS10185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GQS_RS10195	COG0346	lactoylglutathione lyase activity
GQS_RS10205	COG1196	nuclear chromosome segregation
GQS_RS10225	COG0513	Belongs to the DEAD box helicase family
GQS_RS10255	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GQS_RS10270	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GQS_RS10285	COG2894	cell division
GQS_RS10290	COG0330	HflC and HflK could
GQS_RS10305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GQS_RS10325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GQS_RS10330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GQS_RS10335	COG1984	allophanate hydrolase subunit 2
GQS_RS10345	COG1454	alcohol dehydrogenase
GQS_RS10355	COG0483	inositol monophosphate 1-phosphatase activity
GQS_RS10360	COG0705	Rhomboid family
GQS_RS10360	COG0457	Tetratricopeptide repeat
GQS_RS10370	COG1199	ATP-dependent helicase activity
GQS_RS10395	COG1489	DNA binding
GQS_RS10400	COG1215	transferase activity, transferring glycosyl groups
GQS_RS10425	COG3473	Maleate cis-trans isomerase
GQS_RS10430	COG0778	Nitroreductase
GQS_RS10440	COG0301	tRNA thio-modification
GQS_RS10450	COG0301	tRNA thio-modification
GQS_RS10460	COG2814	Major facilitator Superfamily
GQS_RS10465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GQS_RS10465	COG1042	CoA-binding domain protein
GQS_RS10465	COG0045	succinate-CoA ligase (ADP-forming) activity
GQS_RS10500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GQS_RS10540	COG0126	phosphoglycerate kinase activity
GQS_RS10565	COG3842	ATPase activity
GQS_RS10570	COG4208	sulfate ABC transporter
GQS_RS10590	COG1522	sequence-specific DNA binding
GQS_RS10615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GQS_RS10620	COG1122	ATPase activity
GQS_RS10630	COG1268	BioY protein
GQS_RS10645	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
GQS_RS10665	COG4946	Tricorn protease homolog
GQS_RS10665	COG0823	Involved in the tonB-independent uptake of proteins
GQS_RS10665	COG1506	peptidase
GQS_RS10680	COG1444	tRNA N-acetyltransferase activity
GQS_RS10715	COG0017	Asparaginyl-tRNA synthetase
GQS_RS10740	COG0631	protein serine/threonine phosphatase activity
GQS_RS10745	COG0515	serine threonine protein kinase
GQS_RS10745	COG2815	serine threonine protein kinase
GQS_RS10820	COG2813	Specifically methylates the guanine in position
GQS_RS10845	COG2361	Protein of unknown function DUF86