locus-tag	class	description
NUS69_RS00015	COG2379	hydroxypyruvate reductase
NUS69_RS00050	COG1832	CoA-binding protein
NUS69_RS00080	COG0432	Pfam Uncharacterised protein family UPF0047
NUS69_RS00085	COG1160	GTP binding
NUS69_RS00105	COG0714	Associated with various cellular activities
NUS69_RS00130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NUS69_RS00135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NUS69_RS00160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NUS69_RS00165	COG0560	Phosphoserine phosphatase
NUS69_RS00200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUS69_RS00225	COG1051	belongs to the nudix hydrolase family
NUS69_RS00225	COG1056	cytidyltransferase-related domain
NUS69_RS00270	COG2226	methyltransferase
NUS69_RS00300	COG2264	protein methyltransferase activity
NUS69_RS00310	COG2264	protein methyltransferase activity
NUS69_RS00340	COG0778	Nitroreductase
NUS69_RS00345	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NUS69_RS00410	COG0071	Belongs to the small heat shock protein (HSP20) family
NUS69_RS00425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUS69_RS00425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUS69_RS00505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUS69_RS00505	COG1042	CoA-binding domain protein
NUS69_RS00505	COG0045	succinate-CoA ligase (ADP-forming) activity
NUS69_RS00520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUS69_RS00540	COG0303	'Molybdopterin
NUS69_RS00545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NUS69_RS00565	COG0009	L-threonylcarbamoyladenylate synthase
NUS69_RS00580	COG0367	asparagine synthase
NUS69_RS00590	COG2894	cell division
NUS69_RS00625	COG0424	maF-like protein
NUS69_RS00635	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUS69_RS00635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NUS69_RS00655	COG1196	nuclear chromosome segregation
NUS69_RS00680	COG0513	Belongs to the DEAD box helicase family
NUS69_RS00695	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NUS69_RS00710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NUS69_RS00725	COG2894	cell division
NUS69_RS00730	COG0330	HflC and HflK could
NUS69_RS00745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NUS69_RS00775	COG0860	N-Acetylmuramoyl-L-alanine amidase
NUS69_RS00775	COG2247	cell wall binding repeat
NUS69_RS00785	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NUS69_RS00795	COG1487	ribonuclease activity
NUS69_RS00800	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NUS69_RS00805	COG1984	allophanate hydrolase subunit 2
NUS69_RS00815	COG1454	alcohol dehydrogenase
NUS69_RS00825	COG0483	inositol monophosphate 1-phosphatase activity
NUS69_RS00830	COG0705	Rhomboid family
NUS69_RS00830	COG0457	Tetratricopeptide repeat
NUS69_RS00875	COG1199	ATP-dependent helicase activity
NUS69_RS00895	COG1489	DNA binding
NUS69_RS00920	COG3473	Maleate cis-trans isomerase
NUS69_RS00935	COG0301	tRNA thio-modification
NUS69_RS00955	COG0301	tRNA thio-modification
NUS69_RS00970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NUS69_RS00990	COG1042	CoA-binding domain protein
NUS69_RS00990	COG0045	succinate-CoA ligase (ADP-forming) activity
NUS69_RS00990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUS69_RS01025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NUS69_RS01055	COG0126	phosphoglycerate kinase activity
NUS69_RS01060	COG1715	Restriction endonuclease
NUS69_RS01080	COG3842	ATPase activity
NUS69_RS01085	COG1178	ABC-type Fe3 transport system permease component
NUS69_RS01135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NUS69_RS01140	COG1122	ATPase activity
NUS69_RS01150	COG1268	BioY protein
NUS69_RS01175	COG4946	Tricorn protease homolog
NUS69_RS01175	COG1506	peptidase
NUS69_RS01175	COG0823	Involved in the tonB-independent uptake of proteins
NUS69_RS01190	COG1444	tRNA N-acetyltransferase activity
NUS69_RS01210	COG4143	(ABC) transporter
NUS69_RS01220	COG0017	Asparaginyl-tRNA synthetase
NUS69_RS01260	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NUS69_RS01280	COG0402	S-adenosylhomocysteine deaminase activity
NUS69_RS01295	COG0175	sulfate reduction
NUS69_RS01335	COG0105	UTP biosynthetic process
NUS69_RS01380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUS69_RS01385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUS69_RS01400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUS69_RS01410	COG0084	hydrolase, TatD family'
NUS69_RS01425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NUS69_RS01430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUS69_RS01450	COG1201	RNA secondary structure unwinding
NUS69_RS01475	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NUS69_RS01500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NUS69_RS01505	COG1342	Belongs to the UPF0251 family
NUS69_RS01535	COG1028	Short-chain dehydrogenase reductase Sdr
NUS69_RS01570	COG0489	protein tyrosine kinase activity
NUS69_RS01600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NUS69_RS01605	COG2267	carboxylic ester hydrolase activity
NUS69_RS01630	COG0003	Pfam Anion-transporting ATPase
NUS69_RS01645	COG1966	Carbon starvation protein
NUS69_RS01655	COG1830	Aldolase
NUS69_RS01665	COG1301	dicarboxylic acid transport
NUS69_RS01675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUS69_RS01685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NUS69_RS01690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NUS69_RS01700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUS69_RS01705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NUS69_RS01705	COG0140	phosphoribosyl-ATP diphosphatase activity
NUS69_RS01710	COG0107	imidazoleglycerol-phosphate synthase activity
NUS69_RS01715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NUS69_RS01720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NUS69_RS01725	COG0131	Imidazoleglycerol-phosphate dehydratase
NUS69_RS01735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NUS69_RS01775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NUS69_RS01790	COG0735	belongs to the Fur family
NUS69_RS01830	COG2033	superoxide reductase activity
NUS69_RS01835	COG1773	rubredoxin
NUS69_RS01840	COG1592	Rubrerythrin
NUS69_RS01845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NUS69_RS01855	COG0426	domain, Protein
NUS69_RS01860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NUS69_RS01865	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS01895	COG0778	Nitroreductase
NUS69_RS01900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NUS69_RS01905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUS69_RS01910	COG0301	tRNA thio-modification
NUS69_RS01920	COG0396	ATPase activity
NUS69_RS01965	COG1522	sequence-specific DNA binding
NUS69_RS01975	COG0450	alkyl hydroperoxide reductase
NUS69_RS02020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NUS69_RS02025	COG0640	Transcriptional regulator
NUS69_RS02030	COG2217	Heavy metal translocating P-type atpase
NUS69_RS02035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NUS69_RS02035	COG1918	ferrous iron import across plasma membrane
NUS69_RS02070	COG0456	acetyltransferase
NUS69_RS02115	COG0515	serine threonine protein kinase
NUS69_RS02115	COG2815	serine threonine protein kinase
NUS69_RS02125	COG0631	protein serine/threonine phosphatase activity
NUS69_RS02135	COG2217	Heavy metal translocating P-type atpase
NUS69_RS02140	COG1131	(ABC) transporter
NUS69_RS02175	COG2226	methyltransferase
NUS69_RS02180	COG0626	cystathionine gamma-synthase activity
NUS69_RS02220	COG1522	sequence-specific DNA binding
NUS69_RS02225	COG2217	Heavy metal translocating P-type atpase
NUS69_RS02265	COG0450	alkyl hydroperoxide reductase
NUS69_RS02270	COG0243	molybdopterin cofactor binding
NUS69_RS02340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NUS69_RS02400	COG0477	Major facilitator Superfamily
NUS69_RS02405	COG2814	Major facilitator Superfamily
NUS69_RS02420	COG0312	modulator of DNA gyrase
NUS69_RS02425	COG0312	modulator of DNA gyrase
NUS69_RS02450	COG1794	racemase activity, acting on amino acids and derivatives
NUS69_RS02460	COG1993	acr, cog1993
NUS69_RS02465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NUS69_RS02515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NUS69_RS02530	COG0563	adenylate kinase activity
NUS69_RS02545	COG0011	TIGRFAM Protein of
NUS69_RS02550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NUS69_RS02565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NUS69_RS02590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NUS69_RS02600	COG1121	(ABC) transporter
NUS69_RS02620	COG2205	protein histidine kinase activity
NUS69_RS02645	COG1469	GTP cyclohydrolase I activity
NUS69_RS02685	COG1078	dGTPase activity
NUS69_RS02690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NUS69_RS02695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NUS69_RS02700	COG0051	transcription antitermination factor activity, RNA binding
NUS69_RS02725	COG1111	helicase
NUS69_RS02725	COG1205	dead DEAH box helicase
NUS69_RS02735	COG2414	aldehyde ferredoxin oxidoreductase
NUS69_RS02740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NUS69_RS02755	COG1373	ATPase (AAA superfamily
NUS69_RS02770	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
NUS69_RS02785	COG0517	IMP dehydrogenase activity
NUS69_RS02785	COG0617	tRNA 3'-terminal CCA addition
NUS69_RS02785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NUS69_RS02830	COG1454	alcohol dehydrogenase
NUS69_RS02850	COG1129	ABC transporter
NUS69_RS02855	COG1111	helicase
NUS69_RS02855	COG1205	dead DEAH box helicase
NUS69_RS02860	COG1739	Uncharacterized protein family UPF0029
NUS69_RS02890	COG0463	Glycosyl transferase, family 2
NUS69_RS02915	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NUS69_RS02915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUS69_RS02945	COG0315	cyclic pyranopterin monophosphate synthase activity
NUS69_RS02955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NUS69_RS02960	COG0515	serine threonine protein kinase
NUS69_RS02970	COG0459	protein refolding
NUS69_RS02975	COG0501	Belongs to the peptidase M48B family
NUS69_RS02995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NUS69_RS03000	COG0492	ferredoxin-NADP+ reductase activity
NUS69_RS03005	COG1335	isochorismatase
NUS69_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
NUS69_RS03015	COG0493	'glutamate synthase
NUS69_RS03020	COG1899	peptidyl-lysine modification to peptidyl-hypusine
NUS69_RS03035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NUS69_RS03045	COG1078	dGTPase activity
NUS69_RS03070	COG0303	'Molybdopterin
NUS69_RS03075	COG0521	Mo-molybdopterin cofactor biosynthetic process
NUS69_RS03095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NUS69_RS03100	COG1492	cobalamin metabolic process
NUS69_RS03110	COG0746	molybdenum cofactor guanylyltransferase activity
NUS69_RS03115	COG2342	PFAM TM1410 hypothetical-related protein
NUS69_RS03120	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NUS69_RS03135	COG1573	uracil-dna glycosylase
NUS69_RS03140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NUS69_RS03145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NUS69_RS03150	COG2226	methyltransferase
NUS69_RS03170	COG0525	valine-tRNA ligase activity
NUS69_RS03190	COG2264	protein methyltransferase activity
NUS69_RS03200	COG0312	modulator of DNA gyrase
NUS69_RS03235	COG0598	Magnesium transport protein CorA
NUS69_RS03240	COG0012	GTP binding
NUS69_RS03255	COG0163	prenyltransferase activity
NUS69_RS03265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NUS69_RS03275	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NUS69_RS03275	COG1918	ferrous iron import across plasma membrane
NUS69_RS03290	COG0482	sulfurtransferase activity
NUS69_RS03320	COG0006	proline dipeptidase activity
NUS69_RS03335	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
NUS69_RS03355	COG0534	Mate efflux family protein
NUS69_RS03375	COG0423	glycine-tRNA ligase activity
NUS69_RS03380	COG2361	Protein of unknown function DUF86
NUS69_RS03400	COG1872	DUF167
NUS69_RS03415	COG1546	Belongs to the CinA family
NUS69_RS03415	COG1058	Belongs to the CinA family
NUS69_RS03445	COG2096	Adenosyltransferase
NUS69_RS03500	COG2409	Drug exporters of the RND superfamily
NUS69_RS03510	COG1363	Peptidase, m42
NUS69_RS03605	COG1201	RNA secondary structure unwinding
NUS69_RS03610	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS03615	COG1505	serine-type exopeptidase activity
NUS69_RS03620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUS69_RS03620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NUS69_RS03625	COG0307	riboflavin synthase, alpha
NUS69_RS03630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUS69_RS03630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NUS69_RS03650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NUS69_RS03655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NUS69_RS03670	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
NUS69_RS03675	COG1992	Thiamine-phosphate synthase
NUS69_RS03675	COG0351	phosphomethylpyrimidine kinase
NUS69_RS03705	COG1047	Peptidyl-prolyl cis-trans
NUS69_RS03710	COG2223	nitrite transmembrane transporter activity
NUS69_RS03715	COG0215	cysteine-tRNA ligase activity
NUS69_RS03740	COG1079	Belongs to the binding-protein-dependent transport system permease family
NUS69_RS03745	COG4603	Belongs to the binding-protein-dependent transport system permease family
NUS69_RS03750	COG3845	ABC transporter
NUS69_RS03755	COG1744	ABC transporter substrate-binding protein PnrA-like
NUS69_RS03765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NUS69_RS03775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NUS69_RS03800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NUS69_RS03800	COG0674	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS03805	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS03815	COG0674	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS03815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NUS69_RS03820	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS03845	COG0720	synthase
NUS69_RS03875	COG0730	response to heat
NUS69_RS03885	COG0730	response to heat
NUS69_RS03905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NUS69_RS03910	COG0442	prolyl-tRNA aminoacylation
NUS69_RS03920	COG2192	nodulation
NUS69_RS03935	COG0436	Aminotransferase
NUS69_RS03945	COG0501	Belongs to the peptidase M48B family
NUS69_RS03950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NUS69_RS03960	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
NUS69_RS03970	COG1515	deoxyribonuclease V activity
NUS69_RS03990	COG0569	domain protein
NUS69_RS04005	COG1476	TRANSCRIPTIONal
NUS69_RS04015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NUS69_RS04085	COG0640	Transcriptional regulator
NUS69_RS04090	COG1694	Mazg nucleotide pyrophosphohydrolase
NUS69_RS04095	COG1522	sequence-specific DNA binding
NUS69_RS04100	COG1836	PFAM Integral membrane protein DUF92
NUS69_RS04105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NUS69_RS04105	COG0301	tRNA thio-modification
NUS69_RS04125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NUS69_RS04195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NUS69_RS04205	COG0018	arginyl-trna synthetase
NUS69_RS04225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NUS69_RS04250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUS69_RS04260	COG1863	multisubunit Na H antiporter MnhE subunit
NUS69_RS04265	COG2212	antiporter activity
NUS69_RS04270	COG1320	monovalent cation:proton antiporter activity
NUS69_RS04280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NUS69_RS04280	COG2111	Na H antiporter
NUS69_RS04285	COG1006	Multisubunit Na H antiporter MnhC subunit
NUS69_RS04290	COG0651	ATP synthesis coupled electron transport
NUS69_RS04295	COG0651	ATP synthesis coupled electron transport
NUS69_RS04300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NUS69_RS04305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS04315	COG0649	NAD binding
NUS69_RS04320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS04345	COG1522	sequence-specific DNA binding
NUS69_RS04370	COG1151	hydroxylamine reductase activity
NUS69_RS04415	COG1881	PFAM PEBP family protein
NUS69_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
NUS69_RS04485	COG0602	queuosine metabolic process
NUS69_RS04535	COG0359	binds to the 23S rRNA
NUS69_RS04535	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NUS69_RS04545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUS69_RS04545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NUS69_RS04565	COG0667	Aldo Keto reductase
NUS69_RS04570	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NUS69_RS04585	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NUS69_RS04595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NUS69_RS04650	COG3842	ATPase activity
NUS69_RS04655	COG3833	ABC-type maltose transport systems, permease component
NUS69_RS04660	COG1175	transmembrane transport
NUS69_RS04680	COG1554	hydrolase, family 65, central catalytic
NUS69_RS04685	COG0010	Belongs to the arginase family
NUS69_RS04700	COG0475	glutathione-regulated potassium exporter activity
NUS69_RS04715	COG0038	chloride channel
NUS69_RS04725	COG1085	galactose-1-phosphate uridylyltransferase
NUS69_RS04730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NUS69_RS04770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NUS69_RS04780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NUS69_RS04810	COG0252	asparaginase activity
NUS69_RS04815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NUS69_RS04835	COG2894	cell division
NUS69_RS04840	COG1063	alcohol dehydrogenase
NUS69_RS04855	COG0101	tRNA pseudouridine synthase activity
NUS69_RS04860	COG0556	nucleotide-excision repair
NUS69_RS04875	COG1131	(ABC) transporter
NUS69_RS04905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NUS69_RS04910	COG0628	permease
NUS69_RS04965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NUS69_RS04980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NUS69_RS05020	COG1122	ATPase activity
NUS69_RS05025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NUS69_RS05030	COG0024	Methionine aminopeptidase
NUS69_RS05040	COG0516	GMP reductase activity
NUS69_RS05040	COG0517	IMP dehydrogenase activity
NUS69_RS05050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NUS69_RS05065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NUS69_RS05080	COG0504	CTP synthase activity
NUS69_RS05110	COG1473	amidohydrolase
NUS69_RS05120	COG0546	phosphoglycolate phosphatase activity
NUS69_RS05125	COG0585	pseudouridine synthase activity
NUS69_RS05140	COG0017	Asparaginyl-tRNA synthetase
NUS69_RS05150	COG1418	mRNA catabolic process
NUS69_RS05165	COG0546	phosphoglycolate phosphatase activity
NUS69_RS05175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NUS69_RS05200	COG1110	DNA topoisomerase II activity
NUS69_RS05245	COG1203	CRISPR-associated helicase, Cas3
NUS69_RS05260	COG1518	maintenance of DNA repeat elements
NUS69_RS05275	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NUS69_RS05310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NUS69_RS05330	COG1458	PINc domain ribonuclease
NUS69_RS05355	COG2358	TRAP transporter, solute receptor (TAXI family
NUS69_RS05385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NUS69_RS05390	COG0081	regulation of translation
NUS69_RS05415	COG0717	Belongs to the dCTP deaminase family
NUS69_RS05440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NUS69_RS05450	COG0058	SHG alpha-glucan phosphorylase activity
NUS69_RS05455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NUS69_RS05470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NUS69_RS05475	COG1131	(ABC) transporter
NUS69_RS05490	COG2271	Major facilitator Superfamily
NUS69_RS05495	COG2814	Major facilitator Superfamily
NUS69_RS05500	COG0584	glycerophosphoryl diester phosphodiesterase
NUS69_RS05505	COG0584	glycerophosphoryl diester phosphodiesterase
NUS69_RS05560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUS69_RS05565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NUS69_RS05595	COG0085	RNA polymerase activity
NUS69_RS05600	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NUS69_RS05605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NUS69_RS05625	COG0049	tRNA binding
NUS69_RS05650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NUS69_RS05685	COG0436	Aminotransferase
NUS69_RS05720	COG1185	polyribonucleotide nucleotidyltransferase activity
NUS69_RS05735	COG0310	cobalt ion transport
NUS69_RS05750	COG1122	ATPase activity
NUS69_RS05770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NUS69_RS05770	COG0662	Cupin 2, conserved barrel domain protein
NUS69_RS05790	COG2140	Oxalate decarboxylase
NUS69_RS05815	COG1234	tRNA 3'-trailer cleavage
NUS69_RS05840	COG0489	protein tyrosine kinase activity
NUS69_RS05850	COG0746	molybdenum cofactor guanylyltransferase activity
NUS69_RS05860	COG0651	ATP synthesis coupled electron transport
NUS69_RS05870	COG1006	Multisubunit Na H antiporter MnhC subunit
NUS69_RS05900	COG3260	NADH ubiquinone oxidoreductase 20
NUS69_RS05905	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS05910	COG3261	NADH dehydrogenase
NUS69_RS05910	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NUS69_RS05915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NUS69_RS05920	COG0651	ATP synthesis coupled electron transport
NUS69_RS05925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NUS69_RS05935	COG3383	formate dehydrogenase (NAD+) activity
NUS69_RS05940	COG1309	transcriptional regulator
NUS69_RS05945	COG0298	carbon dioxide binding
NUS69_RS05950	COG0409	Hydrogenase expression formation protein
NUS69_RS05955	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NUS69_RS05980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NUS69_RS06005	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUS69_RS06020	COG1404	Belongs to the peptidase S8 family
NUS69_RS06040	COG0574	Belongs to the PEP-utilizing enzyme family
NUS69_RS06040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NUS69_RS06055	COG0534	Mate efflux family protein
NUS69_RS06060	COG0534	Mate efflux family protein
NUS69_RS06065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NUS69_RS06075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NUS69_RS06090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NUS69_RS06095	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NUS69_RS06110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NUS69_RS06115	COG0733	neurotransmitter:sodium symporter activity
NUS69_RS06125	COG0347	Belongs to the P(II) protein family
NUS69_RS06130	COG1543	Belongs to the glycosyl hydrolase 57 family
NUS69_RS06165	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NUS69_RS06185	COG0006	proline dipeptidase activity
NUS69_RS06190	COG0495	leucyl-tRNA aminoacylation
NUS69_RS06210	COG0142	geranyltranstransferase activity
NUS69_RS06215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NUS69_RS06220	COG1304	FMN binding
NUS69_RS06235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NUS69_RS06240	COG2361	Protein of unknown function DUF86
NUS69_RS06260	COG1355	regulation of microtubule-based process
NUS69_RS06265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUS69_RS06270	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NUS69_RS06285	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUS69_RS06290	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NUS69_RS06310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NUS69_RS06325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NUS69_RS06335	COG1522	sequence-specific DNA binding
NUS69_RS06375	COG0052	Belongs to the universal ribosomal protein uS2 family
NUS69_RS06400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NUS69_RS06405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NUS69_RS06420	COG0202	RNA polymerase activity
NUS69_RS06430	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NUS69_RS06435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NUS69_RS06445	COG2813	Specifically methylates the guanine in position
NUS69_RS06455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NUS69_RS06460	COG0300	oxidoreductase activity
NUS69_RS06470	COG1102	Psort location Cytoplasmic, score
NUS69_RS06495	COG0200	Binds to the 23S rRNA
NUS69_RS06505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NUS69_RS06510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NUS69_RS06525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NUS69_RS06530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NUS69_RS06540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NUS69_RS06550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NUS69_RS06555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NUS69_RS06560	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NUS69_RS06575	COG0255	Belongs to the universal ribosomal protein uL29 family
NUS69_RS06580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NUS69_RS06590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NUS69_RS06595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NUS69_RS06600	COG0089	rRNA binding
NUS69_RS06605	COG0088	Forms part of the polypeptide exit tunnel
NUS69_RS06610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NUS69_RS06640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NUS69_RS06655	COG0017	Asparaginyl-tRNA synthetase
NUS69_RS06680	COG0543	2 iron, 2 sulfur cluster binding
NUS69_RS06690	COG3259	Nickel-dependent hydrogenase
NUS69_RS06740	COG0430	RNA-3'-phosphate cyclase activity
NUS69_RS06765	COG0305	Participates in initiation and elongation during chromosome replication
NUS69_RS06765	COG1372	Participates in initiation and elongation during chromosome replication
NUS69_RS06775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NUS69_RS06785	COG5016	pyruvate
NUS69_RS06785	COG0511	ligase activity, forming carbon-carbon bonds
NUS69_RS06790	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NUS69_RS06795	COG0517	IMP dehydrogenase activity
NUS69_RS06795	COG1125	glycine betaine transport
NUS69_RS06835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NUS69_RS06840	COG1185	polyribonucleotide nucleotidyltransferase activity
NUS69_RS06910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS06940	COG1335	isochorismatase
NUS69_RS06950	COG4662	Binding-protein-dependent transport system inner membrane component
NUS69_RS06965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NUS69_RS06965	COG2050	protein possibly involved in aromatic compounds catabolism
NUS69_RS06970	COG1695	Transcriptional regulator
NUS69_RS06990	COG1185	polyribonucleotide nucleotidyltransferase activity
NUS69_RS07030	COG0417	DNA replication proofreading
NUS69_RS07050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUS69_RS07050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUS69_RS07060	COG2078	PFAM AMMECR1 domain protein
NUS69_RS07065	COG0011	TIGRFAM Protein of
NUS69_RS07105	COG1178	ABC-type Fe3 transport system permease component
NUS69_RS07110	COG3842	ATPase activity
NUS69_RS07180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NUS69_RS07185	COG0552	protein localization to endoplasmic reticulum
NUS69_RS07190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NUS69_RS07195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NUS69_RS07255	COG0668	transmembrane transport
NUS69_RS07265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NUS69_RS07265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUS69_RS07280	COG2264	protein methyltransferase activity
NUS69_RS07285	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS07290	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS07375	COG2234	aminopeptidase activity
NUS69_RS07385	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS07495	COG2890	protein-(glutamine-N5) methyltransferase activity
NUS69_RS07565	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUS69_RS07565	COG0519	Catalyzes the synthesis of GMP from XMP
NUS69_RS07580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NUS69_RS07580	COG0519	Catalyzes the synthesis of GMP from XMP
NUS69_RS07590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NUS69_RS07595	COG0047	phosphoribosylformylglycinamidine synthase activity
NUS69_RS07625	COG0151	Belongs to the GarS family
NUS69_RS07630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NUS69_RS07635	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NUS69_RS07640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NUS69_RS07650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NUS69_RS07655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NUS69_RS07670	COG3383	formate dehydrogenase (NAD+) activity
NUS69_RS07675	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NUS69_RS07690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NUS69_RS07695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NUS69_RS07700	COG0517	IMP dehydrogenase activity
NUS69_RS07700	COG0516	GMP reductase activity
NUS69_RS07795	COG1785	Belongs to the alkaline phosphatase family
NUS69_RS07865	COG2046	Belongs to the sulfate adenylyltransferase family
NUS69_RS07890	COG0529	Catalyzes the synthesis of activated sulfate
NUS69_RS07895	COG0730	response to heat
NUS69_RS07970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NUS69_RS07975	COG1216	Glycosyl transferase, family 2
NUS69_RS07980	COG0463	Glycosyl transferase, family 2
NUS69_RS08000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NUS69_RS08010	COG0463	Glycosyl transferase, family 2
NUS69_RS08025	COG0714	Associated with various cellular activities
NUS69_RS08060	COG0647	UMP catabolic process
NUS69_RS08070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NUS69_RS08100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NUS69_RS08135	COG2414	aldehyde ferredoxin oxidoreductase
NUS69_RS08220	COG0297	glycogen (starch) synthase activity
NUS69_RS08225	COG1378	Sugar-specific transcriptional regulator TrmB
NUS69_RS08230	COG0366	Alpha amylase catalytic
NUS69_RS08235	COG2182	Extracellular solute-binding protein
NUS69_RS08240	COG1175	transmembrane transport
NUS69_RS08245	COG3833	ABC-type maltose transport systems, permease component
NUS69_RS08255	COG3842	ATPase activity
NUS69_RS08265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUS69_RS08275	COG1234	tRNA 3'-trailer cleavage
NUS69_RS08280	COG1297	OPT oligopeptide transporter protein
NUS69_RS08290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUS69_RS08310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NUS69_RS08330	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS08370	COG0174	glutamine synthetase
NUS69_RS08390	COG4608	Belongs to the ABC transporter superfamily
NUS69_RS08395	COG0444	Belongs to the ABC transporter superfamily
NUS69_RS08400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NUS69_RS08405	COG0601	transmembrane transport
NUS69_RS08415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NUS69_RS08435	COG1606	tRNA processing
NUS69_RS08450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUS69_RS08455	COG1394	ATPase activity, coupled to movement of substances
NUS69_RS08470	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
NUS69_RS08480	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
NUS69_RS08490	COG1269	ATP hydrolysis coupled proton transport
NUS69_RS08500	COG0569	domain protein
NUS69_RS08505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUS69_RS08510	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUS69_RS08510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NUS69_RS08515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NUS69_RS08550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NUS69_RS08565	COG1131	(ABC) transporter
NUS69_RS08600	COG1122	ATPase activity
NUS69_RS08610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUS69_RS08685	COG4974	Belongs to the 'phage' integrase family
NUS69_RS08690	COG1115	amino acid carrier protein
NUS69_RS08735	COG0475	glutathione-regulated potassium exporter activity
NUS69_RS08745	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NUS69_RS08775	COG0037	tRNA processing
NUS69_RS08790	COG1449	Belongs to the glycosyl hydrolase 57 family
NUS69_RS08820	COG0076	glutamate decarboxylase activity
NUS69_RS08835	COG1216	Glycosyl transferase, family 2
NUS69_RS08845	COG0463	Glycosyl transferase, family 2
NUS69_RS08850	COG3119	arylsulfatase activity
NUS69_RS08855	COG0463	Glycosyl transferase, family 2
NUS69_RS08855	COG1216	Glycosyl transferase, family 2
NUS69_RS08860	COG0750	zinc metalloprotease
NUS69_RS08865	COG0037	tRNA processing
NUS69_RS08895	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NUS69_RS08900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NUS69_RS08925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NUS69_RS08945	COG0714	Associated with various cellular activities
NUS69_RS08970	COG1047	Peptidyl-prolyl cis-trans
NUS69_RS09005	COG1160	GTP binding
NUS69_RS09010	COG0116	Belongs to the methyltransferase superfamily
NUS69_RS09030	COG0179	Fumarylacetoacetate (FAA) hydrolase
NUS69_RS09055	COG0535	radical SAM domain protein
NUS69_RS09085	COG0640	Transcriptional regulator
NUS69_RS09130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NUS69_RS09130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NUS69_RS09145	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NUS69_RS09145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NUS69_RS09150	COG0402	S-adenosylhomocysteine deaminase activity
NUS69_RS09175	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NUS69_RS09210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NUS69_RS09275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NUS69_RS09285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NUS69_RS09295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NUS69_RS09295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NUS69_RS09345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NUS69_RS09355	COG0314	molybdopterin synthase activity
NUS69_RS09375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NUS69_RS09380	COG1522	sequence-specific DNA binding
NUS69_RS09420	COG0148	phosphopyruvate hydratase activity
NUS69_RS09445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NUS69_RS09455	COG0492	ferredoxin-NADP+ reductase activity
NUS69_RS09505	COG0650	Formate hydrogenlyase subunit 4
NUS69_RS09515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS09515	COG0649	NAD binding
NUS69_RS09520	COG3260	NADH ubiquinone oxidoreductase 20
NUS69_RS09530	COG0651	ATP synthesis coupled electron transport
NUS69_RS09535	COG1006	Multisubunit Na H antiporter MnhC subunit
NUS69_RS09540	COG2111	Na H antiporter
NUS69_RS09555	COG1320	monovalent cation:proton antiporter activity
NUS69_RS09560	COG2212	antiporter activity
NUS69_RS09570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NUS69_RS09575	COG0650	Formate hydrogenlyase subunit 4
NUS69_RS09585	COG3261	NADH dehydrogenase
NUS69_RS09585	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NUS69_RS09590	COG3260	NADH ubiquinone oxidoreductase 20
NUS69_RS09600	COG0651	ATP synthesis coupled electron transport
NUS69_RS09625	COG1320	monovalent cation:proton antiporter activity
NUS69_RS09630	COG2212	antiporter activity
NUS69_RS09635	COG1863	multisubunit Na H antiporter MnhE subunit
NUS69_RS09645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NUS69_RS09670	COG0306	phosphate transporter
NUS69_RS09695	COG1506	peptidase
NUS69_RS09695	COG0823	Involved in the tonB-independent uptake of proteins
NUS69_RS09695	COG4946	Tricorn protease homolog
NUS69_RS09735	COG0095	Lipoate-protein ligase
NUS69_RS09785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NUS69_RS09825	COG1346	cytolysis
NUS69_RS09830	COG1380	Effector of murein hydrolase LrgA
NUS69_RS09845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUS69_RS09855	COG1573	uracil-dna glycosylase
NUS69_RS09860	COG1757	Na H antiporter
NUS69_RS09880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NUS69_RS09885	COG2894	cell division
NUS69_RS09900	COG1522	sequence-specific DNA binding
NUS69_RS09980	COG1233	COG1233 Phytoene dehydrogenase and related
NUS69_RS10020	COG1980	fructose-bisphosphate aldolase activity
NUS69_RS10050	COG1628	Protein of unknown function DUF99
NUS69_RS10055	COG1324	tolerance protein
NUS69_RS10060	COG1254	Belongs to the acylphosphatase family
NUS69_RS10085	COG1131	(ABC) transporter
NUS69_RS10110	COG0489	protein tyrosine kinase activity
NUS69_RS10115	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS10120	COG0674	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS10130	COG1013	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS10135	COG0674	pyruvate-flavodoxin oxidoreductase activity
NUS69_RS10150	COG0306	phosphate transporter
NUS69_RS10160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NUS69_RS10195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NUS69_RS10200	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NUS69_RS10205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NUS69_RS10215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NUS69_RS10250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NUS69_RS10265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NUS69_RS10280	COG1846	Transcriptional regulator
NUS69_RS10285	COG0312	modulator of DNA gyrase
NUS69_RS10290	COG0312	modulator of DNA gyrase
NUS69_RS10320	COG0714	Associated with various cellular activities
NUS69_RS10335	COG0434	BtpA family
NUS69_RS10370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NUS69_RS10390	COG0237	dephospho-CoA kinase activity
NUS69_RS10405	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NUS69_RS10410	COG0540	Belongs to the ATCase OTCase family
NUS69_RS10425	COG0432	Pfam Uncharacterised protein family UPF0047
NUS69_RS10460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NUS69_RS10465	COG0312	modulator of DNA gyrase
NUS69_RS10470	COG3885	ferrous iron binding
NUS69_RS10470	COG2078	PFAM AMMECR1 domain protein
NUS69_RS10490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NUS69_RS10505	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NUS69_RS10510	COG4139	cobalamin transport
NUS69_RS10525	COG0419	ATPase involved in DNA repair
NUS69_RS10525	COG0419	ATPase involved in DNA repair
NUS69_RS10530	COG0420	3'-5' exonuclease activity
NUS69_RS10545	COG0433	COG0433 Predicted ATPase
NUS69_RS10550	COG0456	acetyltransferase
NUS69_RS10550	COG1214	PFAM Peptidase M22, glycoprotease
NUS69_RS10565	COG0156	8-amino-7-oxononanoate synthase activity
NUS69_RS10570	COG2255	four-way junction helicase activity
NUS69_RS10575	COG2255	four-way junction helicase activity
NUS69_RS10580	COG2361	Protein of unknown function DUF86
NUS69_RS10595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NUS69_RS10605	COG1530	ribonuclease E activity
NUS69_RS10635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NUS69_RS10680	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NUS69_RS10725	COG2271	Major facilitator Superfamily
NUS69_RS10730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NUS69_RS10745	COG0546	phosphoglycolate phosphatase activity
NUS69_RS10755	COG2131	deaminase
NUS69_RS10760	COG0501	Belongs to the peptidase M48B family
NUS69_RS10795	COG0543	2 iron, 2 sulfur cluster binding
NUS69_RS10800	COG0493	'glutamate synthase
NUS69_RS10800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NUS69_RS10835	COG1141	Ferredoxin
NUS69_RS10840	COG2151	metal-sulfur cluster biosynthetic enzyme
NUS69_RS10860	COG1404	Belongs to the peptidase S8 family
NUS69_RS10865	COG2414	aldehyde ferredoxin oxidoreductase
NUS69_RS10885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NUS69_RS10900	COG0167	dihydroorotate dehydrogenase activity
NUS69_RS10925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NUS69_RS10940	COG0528	UMP kinase activity
NUS69_RS10960	COG0446	pyridine nucleotide-disulphide oxidoreductase
NUS69_RS10975	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NUS69_RS10995	COG2723	6-phospho-beta-galactosidase activity
NUS69_RS11020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NUS69_RS11035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NUS69_RS11060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NUS69_RS11065	COG1522	sequence-specific DNA binding
NUS69_RS11070	COG0693	protein deglycase activity
NUS69_RS11100	COG2095	MarC family integral membrane protein
NUS69_RS11105	COG1765	OsmC-like protein
NUS69_RS11115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NUS69_RS11120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NUS69_RS11125	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NUS69_RS11155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NUS69_RS11195	COG0123	including yeast histone deacetylase and acetoin utilization protein
NUS69_RS11215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NUS69_RS11245	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NUS69_RS11265	COG0440	acetolactate synthase activity
NUS69_RS11270	COG0651	ATP synthesis coupled electron transport
NUS69_RS11295	COG1320	monovalent cation:proton antiporter activity
NUS69_RS11300	COG2212	antiporter activity
NUS69_RS11305	COG1863	multisubunit Na H antiporter MnhE subunit
NUS69_RS11310	COG0509	glycine decarboxylation via glycine cleavage system
NUS69_RS11330	COG0543	2 iron, 2 sulfur cluster binding
NUS69_RS11380	COG1131	(ABC) transporter
NUS69_RS11385	COG1476	TRANSCRIPTIONal
NUS69_RS11415	COG0436	Aminotransferase
NUS69_RS11430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NUS69_RS11435	COG1192	Involved in chromosome partitioning
NUS69_RS11445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NUS69_RS11445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NUS69_RS11455	COG0284	orotidine-5'-phosphate decarboxylase activity
NUS69_RS11475	COG1175	transmembrane transport
NUS69_RS11480	COG0395	ABC-type sugar transport system, permease component
NUS69_RS11485	COG3842	ATPase activity
NUS69_RS11490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NUS69_RS11490	COG1213	nucleotidyl transferase
NUS69_RS11510	COG1131	(ABC) transporter
NUS69_RS11555	COG1850	ribulose-bisphosphate carboxylase activity
NUS69_RS11565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NUS69_RS11610	COG3842	ATPase activity
NUS69_RS11620	COG0438	transferase activity, transferring glycosyl groups
NUS69_RS11625	COG1653	transport
NUS69_RS11630	COG1175	transmembrane transport
NUS69_RS11635	COG0395	ABC-type sugar transport system, permease component
NUS69_RS11650	COG0463	Glycosyl transferase, family 2
NUS69_RS11680	COG3842	ATPase activity