locus-tag	class	description
A3L14_RS00035	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L14_RS00035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_RS00045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A3L14_RS00055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A3L14_RS00125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A3L14_RS00155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L14_RS00160	COG0402	S-adenosylhomocysteine deaminase activity
A3L14_RS00165	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A3L14_RS00165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A3L14_RS00180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A3L14_RS00180	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A3L14_RS00205	COG0640	Transcriptional regulator
A3L14_RS00240	COG0308	aminopeptidase N
A3L14_RS00255	COG0179	Fumarylacetoacetate (FAA) hydrolase
A3L14_RS00275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L14_RS00275	COG0116	Belongs to the methyltransferase superfamily
A3L14_RS00280	COG1160	GTP binding
A3L14_RS00315	COG1047	Peptidyl-prolyl cis-trans
A3L14_RS00340	COG0714	Associated with various cellular activities
A3L14_RS00360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A3L14_RS00375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A3L14_RS00405	COG0037	tRNA processing
A3L14_RS00410	COG0750	zinc metalloprotease
A3L14_RS00415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L14_RS00435	COG0463	Glycosyl transferase, family 2
A3L14_RS00435	COG1216	Glycosyl transferase, family 2
A3L14_RS00460	COG0110	maltose O-acetyltransferase activity
A3L14_RS00470	COG1086	Polysaccharide biosynthesis protein
A3L14_RS00495	COG0076	glutamate decarboxylase activity
A3L14_RS00525	COG1449	Belongs to the glycosyl hydrolase 57 family
A3L14_RS00540	COG0037	tRNA processing
A3L14_RS00555	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A3L14_RS00565	COG0475	glutathione-regulated potassium exporter activity
A3L14_RS00625	COG0681	Belongs to the peptidase S26 family
A3L14_RS00635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_RS00645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A3L14_RS00680	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A3L14_RS00685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L14_RS00690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A3L14_RS00695	COG0569	domain protein
A3L14_RS00705	COG1269	ATP hydrolysis coupled proton transport
A3L14_RS00715	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L14_RS00725	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L14_RS00730	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A3L14_RS00740	COG1394	ATPase activity, coupled to movement of substances
A3L14_RS00745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_RS00765	COG0601	transmembrane transport
A3L14_RS00770	COG1606	tRNA processing
A3L14_RS00790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A3L14_RS00800	COG0601	transmembrane transport
A3L14_RS00805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A3L14_RS00810	COG0444	Belongs to the ABC transporter superfamily
A3L14_RS00815	COG4608	Belongs to the ABC transporter superfamily
A3L14_RS00835	COG0174	glutamine synthetase
A3L14_RS00860	COG0697	spore germination
A3L14_RS00875	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_RS00895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A3L14_RS00905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L14_RS00915	COG1297	OPT oligopeptide transporter protein
A3L14_RS00920	COG1234	tRNA 3'-trailer cleavage
A3L14_RS00925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L14_RS00935	COG3842	ATPase activity
A3L14_RS00945	COG3833	ABC-type maltose transport systems, permease component
A3L14_RS00950	COG1175	transmembrane transport
A3L14_RS00955	COG2182	Extracellular solute-binding protein
A3L14_RS00965	COG1378	Sugar-specific transcriptional regulator TrmB
A3L14_RS01000	COG0697	spore germination
A3L14_RS01010	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_RS01035	COG1373	ATPase (AAA superfamily
A3L14_RS01040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A3L14_RS01060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A3L14_RS01105	COG0714	Associated with various cellular activities
A3L14_RS01120	COG0463	Glycosyl transferase, family 2
A3L14_RS01125	COG1215	transferase activity, transferring glycosyl groups
A3L14_RS01135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L14_RS01170	COG0730	response to heat
A3L14_RS01175	COG0529	Catalyzes the synthesis of activated sulfate
A3L14_RS01200	COG2046	Belongs to the sulfate adenylyltransferase family
A3L14_RS01265	COG1785	Belongs to the alkaline phosphatase family
A3L14_RS01335	COG0516	GMP reductase activity
A3L14_RS01335	COG0517	IMP dehydrogenase activity
A3L14_RS01340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A3L14_RS01350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A3L14_RS01365	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A3L14_RS01370	COG3383	formate dehydrogenase (NAD+) activity
A3L14_RS01395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A3L14_RS01400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L14_RS01405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A3L14_RS01410	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A3L14_RS01415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A3L14_RS01420	COG0151	Belongs to the GarS family
A3L14_RS01435	COG0047	phosphoribosylformylglycinamidine synthase activity
A3L14_RS01450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A3L14_RS01460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L14_RS01460	COG0519	Catalyzes the synthesis of GMP from XMP
A3L14_RS01475	COG0519	Catalyzes the synthesis of GMP from XMP
A3L14_RS01475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A3L14_RS01525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L14_RS01540	COG2890	protein-(glutamine-N5) methyltransferase activity
A3L14_RS01640	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_RS01650	COG2234	aminopeptidase activity
A3L14_RS01715	COG0393	Putative heavy-metal-binding
A3L14_RS01740	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_RS01745	COG2264	protein methyltransferase activity
A3L14_RS01760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L14_RS01760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_RS01765	COG0668	transmembrane transport
A3L14_RS01865	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A3L14_RS01870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A3L14_RS01880	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A3L14_RS01950	COG3842	ATPase activity
A3L14_RS01955	COG1178	ABC-type Fe3 transport system permease component
A3L14_RS01980	COG0011	TIGRFAM Protein of
A3L14_RS01985	COG2078	PFAM AMMECR1 domain protein
A3L14_RS01995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A3L14_RS01995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_RS02015	COG0417	DNA replication proofreading
A3L14_RS02070	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_RS02090	COG1695	Transcriptional regulator
A3L14_RS02095	COG2050	protein possibly involved in aromatic compounds catabolism
A3L14_RS02095	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_RS02110	COG4662	Binding-protein-dependent transport system inner membrane component
A3L14_RS02120	COG1335	isochorismatase
A3L14_RS02150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS02215	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_RS02220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A3L14_RS02260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A3L14_RS02260	COG0517	IMP dehydrogenase activity
A3L14_RS02265	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A3L14_RS02270	COG5016	pyruvate
A3L14_RS02270	COG0511	ligase activity, forming carbon-carbon bonds
A3L14_RS02280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A3L14_RS02290	COG0305	Participates in initiation and elongation during chromosome replication
A3L14_RS02290	COG1372	Participates in initiation and elongation during chromosome replication
A3L14_RS02315	COG0430	RNA-3'-phosphate cyclase activity
A3L14_RS02395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
A3L14_RS02405	COG0543	2 iron, 2 sulfur cluster binding
A3L14_RS02435	COG0017	Asparaginyl-tRNA synthetase
A3L14_RS02450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A3L14_RS02495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A3L14_RS02500	COG0088	Forms part of the polypeptide exit tunnel
A3L14_RS02505	COG0089	rRNA binding
A3L14_RS02510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L14_RS02515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A3L14_RS02525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A3L14_RS02530	COG0255	Belongs to the universal ribosomal protein uL29 family
A3L14_RS02545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A3L14_RS02550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A3L14_RS02555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A3L14_RS02565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L14_RS02575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A3L14_RS02580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A3L14_RS02595	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A3L14_RS02600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A3L14_RS02610	COG0200	Binds to the 23S rRNA
A3L14_RS02635	COG1102	Psort location Cytoplasmic, score
A3L14_RS02645	COG0300	oxidoreductase activity
A3L14_RS02650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A3L14_RS02665	COG2813	Specifically methylates the guanine in position
A3L14_RS02675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L14_RS02680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A3L14_RS02705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A3L14_RS02710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A3L14_RS02735	COG0052	Belongs to the universal ribosomal protein uS2 family
A3L14_RS02775	COG1522	sequence-specific DNA binding
A3L14_RS02785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A3L14_RS02800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L14_RS02820	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A3L14_RS02825	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_RS02850	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A3L14_RS02855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L14_RS02860	COG1355	regulation of microtubule-based process
A3L14_RS02875	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L14_RS02890	COG1304	FMN binding
A3L14_RS02905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A3L14_RS02935	COG0495	leucyl-tRNA aminoacylation
A3L14_RS02945	COG0006	proline dipeptidase activity
A3L14_RS02985	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A3L14_RS03005	COG0864	Transcriptional regulator
A3L14_RS03020	COG1543	Belongs to the glycosyl hydrolase 57 family
A3L14_RS03025	COG0347	Belongs to the P(II) protein family
A3L14_RS03035	COG0733	neurotransmitter:sodium symporter activity
A3L14_RS03040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A3L14_RS03055	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A3L14_RS03060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L14_RS03075	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A3L14_RS03085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A3L14_RS03090	COG0534	Mate efflux family protein
A3L14_RS03095	COG0534	Mate efflux family protein
A3L14_RS03100	COG0574	Belongs to the PEP-utilizing enzyme family
A3L14_RS03100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A3L14_RS03120	COG1404	Belongs to the peptidase S8 family
A3L14_RS03135	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_RS03160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A3L14_RS03185	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A3L14_RS03190	COG0409	Hydrogenase expression formation protein
A3L14_RS03195	COG0298	carbon dioxide binding
A3L14_RS03200	COG0746	molybdenum cofactor guanylyltransferase activity
A3L14_RS03210	COG0489	protein tyrosine kinase activity
A3L14_RS03235	COG1234	tRNA 3'-trailer cleavage
A3L14_RS03255	COG2140	Oxalate decarboxylase
A3L14_RS03275	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
A3L14_RS03275	COG0662	Cupin 2, conserved barrel domain protein
A3L14_RS03295	COG1122	ATPase activity
A3L14_RS03310	COG0310	cobalt ion transport
A3L14_RS03325	COG1185	polyribonucleotide nucleotidyltransferase activity
A3L14_RS03360	COG0436	Aminotransferase
A3L14_RS03365	COG2104	thiamine diphosphate biosynthetic process
A3L14_RS03395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A3L14_RS03410	COG0049	tRNA binding
A3L14_RS03430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L14_RS03435	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A3L14_RS03440	COG0085	RNA polymerase activity
A3L14_RS03470	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L14_RS03475	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L14_RS03530	COG0584	glycerophosphoryl diester phosphodiesterase
A3L14_RS03535	COG0584	glycerophosphoryl diester phosphodiesterase
A3L14_RS03540	COG2814	Major facilitator Superfamily
A3L14_RS03545	COG2271	Major facilitator Superfamily
A3L14_RS03555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A3L14_RS03570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
A3L14_RS03575	COG0058	SHG alpha-glucan phosphorylase activity
A3L14_RS03585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A3L14_RS03610	COG0717	Belongs to the dCTP deaminase family
A3L14_RS03635	COG0081	regulation of translation
A3L14_RS03640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A3L14_RS03670	COG2358	TRAP transporter, solute receptor (TAXI family
A3L14_RS03695	COG1458	PINc domain ribonuclease
A3L14_RS03720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A3L14_RS03750	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A3L14_RS03830	COG1110	DNA topoisomerase II activity
A3L14_RS03855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A3L14_RS03865	COG0546	phosphoglycolate phosphatase activity
A3L14_RS03875	COG1418	mRNA catabolic process
A3L14_RS03885	COG0017	Asparaginyl-tRNA synthetase
A3L14_RS03900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A3L14_RS03910	COG0585	pseudouridine synthase activity
A3L14_RS03915	COG0546	phosphoglycolate phosphatase activity
A3L14_RS03925	COG1473	amidohydrolase
A3L14_RS03955	COG0504	CTP synthase activity
A3L14_RS03970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L14_RS03985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A3L14_RS03995	COG0517	IMP dehydrogenase activity
A3L14_RS03995	COG0516	GMP reductase activity
A3L14_RS04005	COG0024	Methionine aminopeptidase
A3L14_RS04010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A3L14_RS04015	COG1122	ATPase activity
A3L14_RS04055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A3L14_RS04070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A3L14_RS04190	COG0628	permease
A3L14_RS04195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A3L14_RS04215	COG1131	(ABC) transporter
A3L14_RS04225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A3L14_RS04230	COG0556	nucleotide-excision repair
A3L14_RS04235	COG0101	tRNA pseudouridine synthase activity
A3L14_RS04250	COG1063	alcohol dehydrogenase
A3L14_RS04255	COG2894	cell division
A3L14_RS04285	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A3L14_RS04290	COG0252	asparaginase activity
A3L14_RS04320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L14_RS04370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A3L14_RS04375	COG1085	galactose-1-phosphate uridylyltransferase
A3L14_RS04385	COG0038	chloride channel
A3L14_RS04400	COG0475	glutathione-regulated potassium exporter activity
A3L14_RS04415	COG0010	Belongs to the arginase family
A3L14_RS04420	COG1554	hydrolase, family 65, central catalytic
A3L14_RS04440	COG1175	transmembrane transport
A3L14_RS04445	COG3833	ABC-type maltose transport systems, permease component
A3L14_RS04450	COG3842	ATPase activity
A3L14_RS04455	COG0438	transferase activity, transferring glycosyl groups
A3L14_RS04530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A3L14_RS04540	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A3L14_RS04555	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A3L14_RS04570	COG4133	protoheme IX ABC transporter activity
A3L14_RS04600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L14_RS04600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A3L14_RS04615	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A3L14_RS04615	COG0359	binds to the 23S rRNA
A3L14_RS04640	COG0573	inorganic phosphate transmembrane transporter activity
A3L14_RS04645	COG0581	inorganic phosphate transmembrane transporter activity
A3L14_RS04650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A3L14_RS04660	COG0704	Plays a role in the regulation of phosphate uptake
A3L14_RS04710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_RS04735	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_RS04740	COG1881	PFAM PEBP family protein
A3L14_RS04785	COG1151	hydroxylamine reductase activity
A3L14_RS04845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS04850	COG0649	NAD binding
A3L14_RS04860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS04865	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A3L14_RS04870	COG0651	ATP synthesis coupled electron transport
A3L14_RS04875	COG0651	ATP synthesis coupled electron transport
A3L14_RS04880	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L14_RS04885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A3L14_RS04885	COG2111	Na H antiporter
A3L14_RS04895	COG1320	monovalent cation:proton antiporter activity
A3L14_RS04900	COG2212	antiporter activity
A3L14_RS04905	COG1863	multisubunit Na H antiporter MnhE subunit
A3L14_RS04915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_RS04935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A3L14_RS04960	COG0018	arginyl-trna synthetase
A3L14_RS04970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L14_RS05040	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A3L14_RS05060	COG0301	tRNA thio-modification
A3L14_RS05060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A3L14_RS05065	COG1836	PFAM Integral membrane protein DUF92
A3L14_RS05070	COG1522	sequence-specific DNA binding
A3L14_RS05075	COG1694	Mazg nucleotide pyrophosphohydrolase
A3L14_RS05080	COG0640	Transcriptional regulator
A3L14_RS05100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A3L14_RS05150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A3L14_RS05160	COG1476	TRANSCRIPTIONal
A3L14_RS05180	COG0569	domain protein
A3L14_RS05200	COG1515	deoxyribonuclease V activity
A3L14_RS05210	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A3L14_RS05220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A3L14_RS05225	COG0501	Belongs to the peptidase M48B family
A3L14_RS05235	COG0436	Aminotransferase
A3L14_RS05240	COG2192	nodulation
A3L14_RS05250	COG0442	prolyl-tRNA aminoacylation
A3L14_RS05255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L14_RS05275	COG0730	response to heat
A3L14_RS05285	COG0730	response to heat
A3L14_RS05325	COG0720	synthase
A3L14_RS05350	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS05355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L14_RS05355	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS05375	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS05380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A3L14_RS05380	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS05395	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A3L14_RS05405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L14_RS05415	COG1744	ABC transporter substrate-binding protein PnrA-like
A3L14_RS05420	COG3845	ABC transporter
A3L14_RS05425	COG4603	Belongs to the binding-protein-dependent transport system permease family
A3L14_RS05430	COG1079	Belongs to the binding-protein-dependent transport system permease family
A3L14_RS05470	COG0215	cysteine-tRNA ligase activity
A3L14_RS05475	COG2223	nitrite transmembrane transporter activity
A3L14_RS05510	COG0351	phosphomethylpyrimidine kinase
A3L14_RS05510	COG0352	thiamine-phosphate diphosphorylase activity
A3L14_RS05515	COG0352	thiamine-phosphate diphosphorylase activity
A3L14_RS05520	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A3L14_RS05525	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A3L14_RS05535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A3L14_RS05540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A3L14_RS05560	COG0534	Mate efflux family protein
A3L14_RS05565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_RS05575	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_RS05580	COG1201	RNA secondary structure unwinding
A3L14_RS05590	COG2001	Belongs to the MraZ family
A3L14_RS05600	COG1215	transferase activity, transferring glycosyl groups
A3L14_RS05730	COG1363	Peptidase, m42
A3L14_RS05740	COG2409	Drug exporters of the RND superfamily
A3L14_RS05775	COG2096	Adenosyltransferase
A3L14_RS05785	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_RS05800	COG1546	Belongs to the CinA family
A3L14_RS05800	COG1058	Belongs to the CinA family
A3L14_RS05815	COG1872	DUF167
A3L14_RS05860	COG0534	Mate efflux family protein
A3L14_RS05880	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L14_RS05895	COG0006	proline dipeptidase activity
A3L14_RS05930	COG0482	sulfurtransferase activity
A3L14_RS05945	COG1918	ferrous iron import across plasma membrane
A3L14_RS05945	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A3L14_RS05965	COG0163	prenyltransferase activity
A3L14_RS05980	COG0012	GTP binding
A3L14_RS06000	COG0312	modulator of DNA gyrase
A3L14_RS06010	COG2264	protein methyltransferase activity
A3L14_RS06030	COG0525	valine-tRNA ligase activity
A3L14_RS06060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L14_RS06065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L14_RS06070	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A3L14_RS06090	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A3L14_RS06105	COG2342	PFAM TM1410 hypothetical-related protein
A3L14_RS06110	COG0746	molybdenum cofactor guanylyltransferase activity
A3L14_RS06120	COG1492	cobalamin metabolic process
A3L14_RS06125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A3L14_RS06145	COG0521	Mo-molybdopterin cofactor biosynthetic process
A3L14_RS06150	COG0303	'Molybdopterin
A3L14_RS06175	COG1078	dGTPase activity
A3L14_RS06185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_RS06210	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A3L14_RS06215	COG0493	'glutamate synthase
A3L14_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_RS06225	COG1335	isochorismatase
A3L14_RS06230	COG0492	ferredoxin-NADP+ reductase activity
A3L14_RS06250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A3L14_RS06260	COG0459	protein refolding
A3L14_RS06270	COG0515	serine threonine protein kinase
A3L14_RS06275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A3L14_RS06285	COG0315	cyclic pyranopterin monophosphate synthase activity
A3L14_RS06315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A3L14_RS06315	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A3L14_RS06340	COG0463	Glycosyl transferase, family 2
A3L14_RS06370	COG1739	Uncharacterized protein family UPF0029
A3L14_RS06375	COG1205	dead DEAH box helicase
A3L14_RS06375	COG1111	helicase
A3L14_RS06380	COG1129	ABC transporter
A3L14_RS06440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A3L14_RS06440	COG0517	IMP dehydrogenase activity
A3L14_RS06440	COG0617	tRNA 3'-terminal CCA addition
A3L14_RS06455	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A3L14_RS06480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L14_RS06485	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_RS06500	COG0051	transcription antitermination factor activity, RNA binding
A3L14_RS06505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A3L14_RS06515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A3L14_RS06520	COG1078	dGTPase activity
A3L14_RS06560	COG1469	GTP cyclohydrolase I activity
A3L14_RS06585	COG2205	protein histidine kinase activity
A3L14_RS06605	COG1121	(ABC) transporter
A3L14_RS06615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A3L14_RS06660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A3L14_RS06675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A3L14_RS06680	COG0011	TIGRFAM Protein of
A3L14_RS06695	COG0563	adenylate kinase activity
A3L14_RS06710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L14_RS06760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A3L14_RS06765	COG1993	acr, cog1993
A3L14_RS06775	COG1794	racemase activity, acting on amino acids and derivatives
A3L14_RS06785	COG0312	modulator of DNA gyrase
A3L14_RS06790	COG0312	modulator of DNA gyrase
A3L14_RS06805	COG2814	Major facilitator Superfamily
A3L14_RS06810	COG0477	Major facilitator Superfamily
A3L14_RS06865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A3L14_RS06945	COG0243	molybdopterin cofactor binding
A3L14_RS06950	COG0450	alkyl hydroperoxide reductase
A3L14_RS06975	COG2217	Heavy metal translocating P-type atpase
A3L14_RS06980	COG1522	sequence-specific DNA binding
A3L14_RS07025	COG0626	cystathionine gamma-synthase activity
A3L14_RS07045	COG2217	Heavy metal translocating P-type atpase
A3L14_RS07055	COG0631	protein serine/threonine phosphatase activity
A3L14_RS07060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_RS07065	COG0515	serine threonine protein kinase
A3L14_RS07065	COG2815	serine threonine protein kinase
A3L14_RS07120	COG0456	acetyltransferase
A3L14_RS07135	COG2217	Heavy metal translocating P-type atpase
A3L14_RS07140	COG0640	Transcriptional regulator
A3L14_RS07145	COG0697	spore germination
A3L14_RS07175	COG0450	alkyl hydroperoxide reductase
A3L14_RS07185	COG1522	sequence-specific DNA binding
A3L14_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
A3L14_RS07240	COG0396	ATPase activity
A3L14_RS07250	COG0301	tRNA thio-modification
A3L14_RS07255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A3L14_RS07260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A3L14_RS07290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L14_RS07290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A3L14_RS07295	COG1012	belongs to the aldehyde dehydrogenase family
A3L14_RS07305	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS07315	COG0426	domain, Protein
A3L14_RS07325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A3L14_RS07330	COG1592	Rubrerythrin
A3L14_RS07335	COG1773	rubredoxin
A3L14_RS07340	COG2033	superoxide reductase activity
A3L14_RS07380	COG0735	belongs to the Fur family
A3L14_RS07450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A3L14_RS07460	COG0131	Imidazoleglycerol-phosphate dehydratase
A3L14_RS07475	COG0107	imidazoleglycerol-phosphate synthase activity
A3L14_RS07480	COG0140	phosphoribosyl-ATP diphosphatase activity
A3L14_RS07480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A3L14_RS07485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A3L14_RS07495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A3L14_RS07500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A3L14_RS07515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_RS07525	COG1301	dicarboxylic acid transport
A3L14_RS07535	COG1830	Aldolase
A3L14_RS07540	COG5016	pyruvate
A3L14_RS07540	COG0511	ligase activity, forming carbon-carbon bonds
A3L14_RS07545	COG1966	Carbon starvation protein
A3L14_RS07560	COG0003	Pfam Anion-transporting ATPase
A3L14_RS07585	COG2267	carboxylic ester hydrolase activity
A3L14_RS07595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A3L14_RS07620	COG0489	protein tyrosine kinase activity
A3L14_RS07670	COG1342	Belongs to the UPF0251 family
A3L14_RS07680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A3L14_RS07705	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_RS07725	COG0477	Major facilitator Superfamily
A3L14_RS07745	COG1201	RNA secondary structure unwinding
A3L14_RS07755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A3L14_RS07760	COG5434	Belongs to the glycosyl hydrolase 28 family
A3L14_RS07770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A3L14_RS07785	COG0084	hydrolase, TatD family'
A3L14_RS07795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A3L14_RS07820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A3L14_RS07825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L14_RS07830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A3L14_RS07840	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A3L14_RS07850	COG0105	UTP biosynthetic process
A3L14_RS07890	COG0175	sulfate reduction
A3L14_RS07905	COG0402	S-adenosylhomocysteine deaminase activity
A3L14_RS07925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A3L14_RS07965	COG0017	Asparaginyl-tRNA synthetase
A3L14_RS07975	COG4143	(ABC) transporter
A3L14_RS07995	COG1444	tRNA N-acetyltransferase activity
A3L14_RS08010	COG1506	peptidase
A3L14_RS08010	COG4946	Tricorn protease homolog
A3L14_RS08010	COG0823	Involved in the tonB-independent uptake of proteins
A3L14_RS08035	COG1268	BioY protein
A3L14_RS08040	COG1827	regulation of RNA biosynthetic process
A3L14_RS08045	COG1122	ATPase activity
A3L14_RS08050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A3L14_RS08100	COG1178	ABC-type Fe3 transport system permease component
A3L14_RS08105	COG3842	ATPase activity
A3L14_RS08115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A3L14_RS08130	COG0126	phosphoglycerate kinase activity
A3L14_RS08160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A3L14_RS08200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_RS08200	COG1042	CoA-binding domain protein
A3L14_RS08200	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L14_RS08235	COG0301	tRNA thio-modification
A3L14_RS08245	COG0301	tRNA thio-modification
A3L14_RS08260	COG3473	Maleate cis-trans isomerase
A3L14_RS08280	COG1489	DNA binding
A3L14_RS08355	COG0457	Tetratricopeptide repeat
A3L14_RS08355	COG0705	Rhomboid family
A3L14_RS08360	COG0483	inositol monophosphate 1-phosphatase activity
A3L14_RS08370	COG1454	alcohol dehydrogenase
A3L14_RS08380	COG1984	allophanate hydrolase subunit 2
A3L14_RS08385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A3L14_RS08390	COG1487	ribonuclease activity
A3L14_RS08400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A3L14_RS08450	COG0330	HflC and HflK could
A3L14_RS08455	COG2894	cell division
A3L14_RS08470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A3L14_RS08485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A3L14_RS08500	COG0513	Belongs to the DEAD box helicase family
A3L14_RS08525	COG1196	nuclear chromosome segregation
A3L14_RS08545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_RS08545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_RS08590	COG2894	cell division
A3L14_RS08600	COG0367	asparagine synthase
A3L14_RS08615	COG0009	L-threonylcarbamoyladenylate synthase
A3L14_RS08640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A3L14_RS08645	COG0303	'Molybdopterin
A3L14_RS08660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_RS08675	COG0045	succinate-CoA ligase (ADP-forming) activity
A3L14_RS08675	COG1042	CoA-binding domain protein
A3L14_RS08675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A3L14_RS08750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_RS08750	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A3L14_RS08755	COG1793	dna ligase
A3L14_RS08755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A3L14_RS08765	COG0071	Belongs to the small heat shock protein (HSP20) family
A3L14_RS08770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_RS08815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A3L14_RS08820	COG0778	Nitroreductase
A3L14_RS08840	COG0312	modulator of DNA gyrase
A3L14_RS08935	COG1056	cytidyltransferase-related domain
A3L14_RS08935	COG1051	belongs to the nudix hydrolase family
A3L14_RS08965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L14_RS09000	COG0560	Phosphoserine phosphatase
A3L14_RS09005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A3L14_RS09030	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A3L14_RS09035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A3L14_RS09055	COG1160	GTP binding
A3L14_RS09060	COG0432	Pfam Uncharacterised protein family UPF0047
A3L14_RS09080	COG1832	CoA-binding protein
A3L14_RS09115	COG2379	hydroxypyruvate reductase
A3L14_RS09125	COG3842	ATPase activity
A3L14_RS09130	COG0581	inorganic phosphate transmembrane transporter activity
A3L14_RS09150	COG0673	inositol 2-dehydrogenase activity
A3L14_RS09155	COG0463	Glycosyl transferase, family 2
A3L14_RS09200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A3L14_RS09210	COG1850	ribulose-bisphosphate carboxylase activity
A3L14_RS09255	COG1131	(ABC) transporter
A3L14_RS09280	COG1213	nucleotidyl transferase
A3L14_RS09280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A3L14_RS09295	COG0284	orotidine-5'-phosphate decarboxylase activity
A3L14_RS09305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A3L14_RS09305	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A3L14_RS09315	COG1192	Involved in chromosome partitioning
A3L14_RS09320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A3L14_RS09335	COG0436	Aminotransferase
A3L14_RS09340	COG2119	membrane
A3L14_RS09370	COG1476	TRANSCRIPTIONal
A3L14_RS09375	COG1131	(ABC) transporter
A3L14_RS09430	COG0543	2 iron, 2 sulfur cluster binding
A3L14_RS09445	COG0509	glycine decarboxylation via glycine cleavage system
A3L14_RS09450	COG1863	multisubunit Na H antiporter MnhE subunit
A3L14_RS09455	COG2212	antiporter activity
A3L14_RS09460	COG1320	monovalent cation:proton antiporter activity
A3L14_RS09485	COG0651	ATP synthesis coupled electron transport
A3L14_RS09490	COG0440	acetolactate synthase activity
A3L14_RS09510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A3L14_RS09540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A3L14_RS09615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A3L14_RS09645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A3L14_RS09650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A3L14_RS09655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A3L14_RS09665	COG1765	OsmC-like protein
A3L14_RS09670	COG2095	MarC family integral membrane protein
A3L14_RS09700	COG0693	protein deglycase activity
A3L14_RS09705	COG1522	sequence-specific DNA binding
A3L14_RS09710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L14_RS09730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A3L14_RS09750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A3L14_RS09760	COG2814	Major facilitator Superfamily
A3L14_RS09780	COG2723	6-phospho-beta-galactosidase activity
A3L14_RS09805	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A3L14_RS09820	COG0446	pyridine nucleotide-disulphide oxidoreductase
A3L14_RS09850	COG0528	UMP kinase activity
A3L14_RS09890	COG0167	dihydroorotate dehydrogenase activity
A3L14_RS09895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A3L14_RS09915	COG2414	aldehyde ferredoxin oxidoreductase
A3L14_RS09920	COG1404	Belongs to the peptidase S8 family
A3L14_RS09940	COG2151	metal-sulfur cluster biosynthetic enzyme
A3L14_RS09945	COG1141	Ferredoxin
A3L14_RS09970	COG0493	'glutamate synthase
A3L14_RS09975	COG0543	2 iron, 2 sulfur cluster binding
A3L14_RS10010	COG0501	Belongs to the peptidase M48B family
A3L14_RS10015	COG2131	deaminase
A3L14_RS10025	COG0546	phosphoglycolate phosphatase activity
A3L14_RS10030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A3L14_RS10040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A3L14_RS10045	COG2271	Major facilitator Superfamily
A3L14_RS10070	COG1446	asparaginase
A3L14_RS10090	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A3L14_RS10140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A3L14_RS10180	COG1530	ribonuclease E activity
A3L14_RS10190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_RS10205	COG2255	four-way junction helicase activity
A3L14_RS10210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A3L14_RS10215	COG0156	8-amino-7-oxononanoate synthase activity
A3L14_RS10235	COG1214	PFAM Peptidase M22, glycoprotease
A3L14_RS10235	COG0456	acetyltransferase
A3L14_RS10240	COG0433	COG0433 Predicted ATPase
A3L14_RS10250	COG0419	ATPase involved in DNA repair
A3L14_RS10250	COG0419	ATPase involved in DNA repair
A3L14_RS10265	COG4139	cobalamin transport
A3L14_RS10270	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A3L14_RS10300	COG3885	ferrous iron binding
A3L14_RS10300	COG2078	PFAM AMMECR1 domain protein
A3L14_RS10315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A3L14_RS10350	COG0432	Pfam Uncharacterised protein family UPF0047
A3L14_RS10365	COG0540	Belongs to the ATCase OTCase family
A3L14_RS10370	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A3L14_RS10405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A3L14_RS10425	COG0434	BtpA family
A3L14_RS10440	COG0714	Associated with various cellular activities
A3L14_RS10470	COG0312	modulator of DNA gyrase
A3L14_RS10475	COG0312	modulator of DNA gyrase
A3L14_RS10480	COG1846	Transcriptional regulator
A3L14_RS10495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A3L14_RS10530	COG0281	malic enzyme
A3L14_RS10545	COG1373	ATPase (AAA superfamily
A3L14_RS10550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A3L14_RS10560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A3L14_RS10565	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A3L14_RS10570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A3L14_RS10605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A3L14_RS10610	COG0306	phosphate transporter
A3L14_RS10625	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS10630	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS10640	COG0674	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS10645	COG1013	pyruvate-flavodoxin oxidoreductase activity
A3L14_RS10650	COG0489	protein tyrosine kinase activity
A3L14_RS10675	COG1131	(ABC) transporter
A3L14_RS10690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A3L14_RS10700	COG1254	Belongs to the acylphosphatase family
A3L14_RS10705	COG1324	tolerance protein
A3L14_RS10710	COG1628	Protein of unknown function DUF99
A3L14_RS10740	COG1980	fructose-bisphosphate aldolase activity
A3L14_RS10775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A3L14_RS10850	COG1522	sequence-specific DNA binding
A3L14_RS10865	COG2894	cell division
A3L14_RS10870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A3L14_RS10890	COG1757	Na H antiporter
A3L14_RS10895	COG1573	uracil-dna glycosylase
A3L14_RS10905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A3L14_RS10920	COG1380	Effector of murein hydrolase LrgA
A3L14_RS10925	COG1346	cytolysis
A3L14_RS10960	COG1404	Belongs to the peptidase S8 family
A3L14_RS11185	COG0095	Lipoate-protein ligase
A3L14_RS11215	COG2226	methyltransferase
A3L14_RS11220	COG4946	Tricorn protease homolog
A3L14_RS11220	COG1506	peptidase
A3L14_RS11220	COG0823	Involved in the tonB-independent uptake of proteins
A3L14_RS11245	COG0306	phosphate transporter
A3L14_RS11270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A3L14_RS11280	COG1863	multisubunit Na H antiporter MnhE subunit
A3L14_RS11285	COG2212	antiporter activity
A3L14_RS11290	COG1320	monovalent cation:proton antiporter activity
A3L14_RS11315	COG0651	ATP synthesis coupled electron transport
A3L14_RS11325	COG3260	NADH ubiquinone oxidoreductase 20
A3L14_RS11330	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS11330	COG0649	NAD binding
A3L14_RS11330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS11340	COG0650	Formate hydrogenlyase subunit 4
A3L14_RS11345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS11355	COG2212	antiporter activity
A3L14_RS11360	COG1320	monovalent cation:proton antiporter activity
A3L14_RS11375	COG2111	Na H antiporter
A3L14_RS11380	COG1006	Multisubunit Na H antiporter MnhC subunit
A3L14_RS11385	COG0651	ATP synthesis coupled electron transport
A3L14_RS11395	COG3260	NADH ubiquinone oxidoreductase 20
A3L14_RS11400	COG0649	NAD binding
A3L14_RS11400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A3L14_RS11410	COG0650	Formate hydrogenlyase subunit 4
A3L14_RS11465	COG0492	ferredoxin-NADP+ reductase activity
A3L14_RS11480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A3L14_RS11505	COG0148	phosphopyruvate hydratase activity
A3L14_RS11520	COG1522	sequence-specific DNA binding
A3L14_RS11525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A3L14_RS11545	COG0314	molybdopterin synthase activity