locus-tag	class	description
THEYE_A0001	COG1797	cobyrinic acid a,c-diamide synthase activity
THEYE_A0003	COG2920	part of a sulfur-relay system
THEYE_A0010	COG0504	CTP synthase activity
THEYE_A0011	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
THEYE_A0012	COG0815	Transfers the fatty acyl group on membrane lipoproteins
THEYE_A0013	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
THEYE_A0015	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THEYE_A0016	COG0592	DNA-directed DNA polymerase activity
THEYE_A0017	COG0187	DNA topoisomerase II activity
THEYE_A0018	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THEYE_A0020	COG2257	FlhB HrpN YscU SpaS Family
THEYE_A0026	COG0798	PFAM Bile acid sodium symporter
THEYE_A0030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
THEYE_A0031	COG3162	membrane
THEYE_A0032	COG2176	DNA-directed DNA polymerase activity
THEYE_A0035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
THEYE_A0037	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
THEYE_A0039	COG2204	response regulator
THEYE_A0041	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
THEYE_A0044	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
THEYE_A0046	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THEYE_A0047	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THEYE_A0052	COG0739	heme binding
THEYE_A0054	COG4974	Belongs to the 'phage' integrase family
THEYE_A0060	COG1353	crispr-associated protein
THEYE_A0062	COG1337	RAMP superfamily
THEYE_A0069	COG2333	competence protein COMEC
THEYE_A0069	COG0658	competence protein
THEYE_A0070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
THEYE_A0073	COG4956	integral membrane protein (PIN domain superfamily)
THEYE_A0074	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
THEYE_A0074	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
THEYE_A0078	COG1242	4 iron, 4 sulfur cluster binding
THEYE_A0079	COG0606	chelatase, subunit chli
THEYE_A0081	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
THEYE_A0082	COG2226	methyltransferase
THEYE_A0083	COG0475	glutathione-regulated potassium exporter activity
THEYE_A0084	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
THEYE_A0087	COG0095	Lipoate-protein ligase
THEYE_A0089	COG3494	Protein of unknown function (DUF1009)
THEYE_A0090	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THEYE_A0091	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THEYE_A0092	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THEYE_A0094	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THEYE_A0098	COG0681	Belongs to the peptidase S26 family
THEYE_A0099	COG0481	GTPase activity
THEYE_A0100	COG1940	carbohydrate kinase activity
THEYE_A0101	COG1028	Short-chain dehydrogenase reductase Sdr
THEYE_A0102	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THEYE_A0103	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THEYE_A0111	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
THEYE_A0112	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THEYE_A0113	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
THEYE_A0114	COG0473	3-isopropylmalate dehydrogenase activity
THEYE_A0115	COG0066	3-isopropylmalate dehydratase activity
THEYE_A0116	COG1309	transcriptional regulator
THEYE_A0120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THEYE_A0121	COG1136	(ABC) transporter
THEYE_A0122	COG0577	efflux transmembrane transporter activity
THEYE_A0122	COG1136	(ABC) transporter
THEYE_A0124	COG2204	response regulator
THEYE_A0127	COG1193	negative regulation of DNA recombination
THEYE_A0134	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THEYE_A0136	COG0432	Pfam Uncharacterised protein family UPF0047
THEYE_A0137	COG0436	Aminotransferase
THEYE_A0140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
THEYE_A0145	COG3852	Histidine kinase
THEYE_A0147	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
THEYE_A0152	COG0166	Belongs to the GPI family
THEYE_A0153	COG1525	nuclease
THEYE_A0154	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
THEYE_A0155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THEYE_A0157	COG5002	protein histidine kinase activity
THEYE_A0158	COG0735	belongs to the Fur family
THEYE_A0159	COG2193	ferroxidase activity
THEYE_A0160	COG0426	domain, Protein
THEYE_A0161	COG1592	Rubrerythrin
THEYE_A0165	COG0719	Fe-S assembly protein
THEYE_A0166	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THEYE_A0167	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
THEYE_A0170	COG1530	ribonuclease E activity
THEYE_A0172	COG5001	Diguanylate cyclase
THEYE_A0172	COG3300	MHYT domain
THEYE_A0173	COG3920	Histidine kinase
THEYE_A0174	COG0840	transmembrane signaling receptor activity
THEYE_A0181	COG3437	response regulator, receiver
THEYE_A0182	COG0784	Response regulator, receiver
THEYE_A0183	COG2202	Pas domain
THEYE_A0183	COG2205	protein histidine kinase activity
THEYE_A0186	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
THEYE_A0189	COG2226	methyltransferase
THEYE_A0190	COG0343	queuine tRNA-ribosyltransferase activity
THEYE_A0191	COG1151	hydroxylamine reductase activity
THEYE_A0193	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
THEYE_A0194	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THEYE_A0202	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
THEYE_A0205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THEYE_A0205	COG0519	Catalyzes the synthesis of GMP from XMP
THEYE_A0206	COG0517	IMP dehydrogenase activity
THEYE_A0206	COG0516	GMP reductase activity
THEYE_A0208	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THEYE_A0208	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
THEYE_A0213	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THEYE_A0214	COG1459	type II secretion system
THEYE_A0215	COG3409	Peptidoglycan-binding domain 1 protein
THEYE_A0215	COG3267	Type II secretory pathway component ExeA
THEYE_A0218	COG1379	DNA repair
THEYE_A0220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
THEYE_A0221	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THEYE_A0223	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
THEYE_A0224	COG0494	nUDIX hydrolase
THEYE_A0225	COG0750	zinc metalloprotease
THEYE_A0226	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
THEYE_A0227	COG0575	Belongs to the CDS family
THEYE_A0228	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
THEYE_A0233	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
THEYE_A0234	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
THEYE_A0235	COG1660	Displays ATPase and GTPase activities
THEYE_A0236	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THEYE_A0237	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THEYE_A0238	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THEYE_A0239	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THEYE_A0241	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THEYE_A0242	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THEYE_A0244	COG2855	membrane
THEYE_A0245	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
THEYE_A0246	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THEYE_A0247	COG0126	phosphoglycerate kinase activity
THEYE_A0251	COG0542	response to heat
THEYE_A0252	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
THEYE_A0254	COG0544	peptidyl-prolyl cis-trans isomerase activity
THEYE_A0255	COG0740	serine-type endopeptidase activity
THEYE_A0256	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THEYE_A0262	COG3852	Histidine kinase
THEYE_A0268	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THEYE_A0270	COG1157	protein secretion by the type III secretion system
THEYE_A0274	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
THEYE_A0276	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THEYE_A0277	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THEYE_A0278	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
THEYE_A0278	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
THEYE_A0279	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THEYE_A0280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THEYE_A0281	COG1862	Preprotein translocase
THEYE_A0282	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THEYE_A0306	COG0582	viral genome integration into host DNA
THEYE_A0309	COG1598	PFAM Uncharacterised protein family UPF0150
THEYE_A0315	COG0582	viral genome integration into host DNA
THEYE_A0318	COG1458	PINc domain ribonuclease
THEYE_A0319	COG0825	malonyl-CoA metabolic process
THEYE_A0320	COG0587	DNA-directed DNA polymerase activity
THEYE_A0324	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THEYE_A0326	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THEYE_A0326	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
THEYE_A0328	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THEYE_A0329	COG0242	peptide deformylase activity
THEYE_A0331	COG0655	NAD(P)H dehydrogenase (quinone) activity
THEYE_A0332	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THEYE_A0332	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THEYE_A0333	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THEYE_A0336	COG0359	binds to the 23S rRNA
THEYE_A0337	COG0305	Participates in initiation and elongation during chromosome replication
THEYE_A0338	COG1355	regulation of microtubule-based process
THEYE_A0340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THEYE_A0341	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
THEYE_A0345	COG1381	Involved in DNA repair and RecF pathway recombination
THEYE_A0348	COG2095	MarC family integral membrane protein
THEYE_A0349	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
THEYE_A0350	COG0588	phosphoglycerate mutase activity
THEYE_A0351	COG1663	tetraacyldisaccharide 4'-kinase activity
THEYE_A0360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
THEYE_A0361	COG0303	'Molybdopterin
THEYE_A0362	COG1090	epimerase
THEYE_A0364	COG0709	Synthesizes selenophosphate from selenide and ATP
THEYE_A0365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
THEYE_A0366	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
THEYE_A0367	COG0254	rRNA binding
THEYE_A0368	COG3872	metal-dependent enzyme
THEYE_A0369	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THEYE_A0370	COG2890	protein-(glutamine-N5) methyltransferase activity
THEYE_A0372	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THEYE_A0373	COG3851	Histidine kinase
THEYE_A0374	COG2197	response regulator
THEYE_A0375	COG2814	Major facilitator Superfamily
THEYE_A0376	COG1494	fructose-1,6-bisphosphatase
THEYE_A0381	COG2003	Belongs to the UPF0758 family
THEYE_A0382	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THEYE_A0382	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THEYE_A0383	COG1774	PSP1 C-terminal conserved region
THEYE_A0385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THEYE_A0389	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
THEYE_A0390	COG0840	transmembrane signaling receptor activity
THEYE_A0391	COG0643	Histidine kinase
THEYE_A0391	COG0784	Response regulator, receiver
THEYE_A0391	COG2198	Histidine kinase
THEYE_A0393	COG0745	RESPONSE REGULATOR receiver
THEYE_A0394	COG0745	RESPONSE REGULATOR receiver
THEYE_A0397	COG0352	thiamine-phosphate diphosphorylase activity
THEYE_A0398	COG0439	Biotin carboxylase
THEYE_A0399	COG0511	ligase activity, forming carbon-carbon bonds
THEYE_A0400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THEYE_A0401	COG0006	proline dipeptidase activity
THEYE_A0402	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THEYE_A0403	COG1758	RNA polymerase activity
THEYE_A0404	COG0194	GDP metabolic process
THEYE_A0405	COG2052	Domain of unknown function (DUF370)
THEYE_A0406	COG1561	YicC-like family, N-terminal region
THEYE_A0407	COG1872	DUF167
THEYE_A0411	COG0463	Glycosyl transferase, family 2
THEYE_A0417	COG0745	RESPONSE REGULATOR receiver
THEYE_A0423	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
THEYE_A0425	COG0438	transferase activity, transferring glycosyl groups
THEYE_A0426	COG0859	PFAM glycosyl transferase family 9
THEYE_A0429	COG0438	transferase activity, transferring glycosyl groups
THEYE_A0433	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THEYE_A0434	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THEYE_A0435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
THEYE_A0436	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
THEYE_A0438	COG0840	transmembrane signaling receptor activity
THEYE_A0440	COG0840	transmembrane signaling receptor activity
THEYE_A0443	COG2022	thiamine diphosphate biosynthetic process
THEYE_A0444	COG0352	thiamine-phosphate diphosphorylase activity
THEYE_A0445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
THEYE_A0446	COG2072	flavoprotein involved in K transport
THEYE_A0448	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THEYE_A0448	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THEYE_A0449	COG0863	Belongs to the N(4) N(6)-methyltransferase family
THEYE_A0454	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THEYE_A0455	COG1063	alcohol dehydrogenase
THEYE_A0458	COG0617	tRNA 3'-terminal CCA addition
THEYE_A0459	COG1490	D-aminoacyl-tRNA deacylase activity
THEYE_A0460	COG3437	response regulator, receiver
THEYE_A0461	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
THEYE_A0462	COG1434	Gram-negative-bacterium-type cell wall biogenesis
THEYE_A0463	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THEYE_A0466	COG1598	PFAM Uncharacterised protein family UPF0150
THEYE_A0471	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A0473	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A0476	COG0529	Catalyzes the synthesis of activated sulfate
THEYE_A0479	COG2089	acid synthase
THEYE_A0480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THEYE_A0482	COG1083	cytidylyl-transferase
THEYE_A0484	COG0367	asparagine synthase
THEYE_A0485	COG2226	methyltransferase
THEYE_A0486	COG0438	transferase activity, transferring glycosyl groups
THEYE_A0487	COG1215	transferase activity, transferring glycosyl groups
THEYE_A0491	COG2226	methyltransferase
THEYE_A0495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A0496	COG0673	inositol 2-dehydrogenase activity
THEYE_A0497	COG0297	glycogen (starch) synthase activity
THEYE_A0499	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
THEYE_A0504	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
THEYE_A0506	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
THEYE_A0507	COG0512	Glutamine amidotransferase of anthranilate synthase
THEYE_A0508	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THEYE_A0513	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THEYE_A0529	COG2234	aminopeptidase activity
THEYE_A0531	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
THEYE_A0532	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
THEYE_A0533	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THEYE_A0536	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THEYE_A0539	COG0232	Belongs to the dGTPase family. Type 2 subfamily
THEYE_A0540	COG0736	holo-[acyl-carrier-protein] synthase activity
THEYE_A0541	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THEYE_A0542	COG0543	2 iron, 2 sulfur cluster binding
THEYE_A0543	COG0167	dihydroorotate dehydrogenase activity
THEYE_A0545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
THEYE_A0547	COG0585	pseudouridine synthase activity
THEYE_A0549	COG1187	pseudouridine synthase activity
THEYE_A0550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THEYE_A0553	COG0165	Argininosuccinate lyase
THEYE_A0554	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THEYE_A0555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
THEYE_A0556	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THEYE_A0559	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
THEYE_A0560	COG0159	tryptophan synthase activity
THEYE_A0561	COG0133	tryptophan synthase activity
THEYE_A0563	COG0741	lytic transglycosylase activity
THEYE_A0564	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
THEYE_A0567	COG1960	acyl-CoA dehydrogenase activity
THEYE_A0568	COG0312	modulator of DNA gyrase
THEYE_A0569	COG0720	synthase
THEYE_A0572	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
THEYE_A0576	COG1487	ribonuclease activity
THEYE_A0580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THEYE_A0581	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THEYE_A0583	COG1214	PFAM Peptidase M22, glycoprotease
THEYE_A0584	COG0357	Ribosomal RNA small subunit methyltransferase G
THEYE_A0585	COG0445	tRNA wobble uridine modification
THEYE_A0588	COG0463	Glycosyl transferase, family 2
THEYE_A0589	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
THEYE_A0593	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A0605	COG0459	protein refolding
THEYE_A0606	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THEYE_A0611	COG0745	RESPONSE REGULATOR receiver
THEYE_A0612	COG5002	protein histidine kinase activity
THEYE_A0614	COG0425	Belongs to the sulfur carrier protein TusA family
THEYE_A0617	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THEYE_A0623	COG1196	nuclear chromosome segregation
THEYE_A0623	COG0741	lytic transglycosylase activity
THEYE_A0623	COG0739	heme binding
THEYE_A0624	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
THEYE_A0626	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THEYE_A0627	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THEYE_A0628	COG0018	arginyl-trna synthetase
THEYE_A0629	COG0047	phosphoribosylformylglycinamidine synthase activity
THEYE_A0629	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THEYE_A0631	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THEYE_A0633	COG1353	crispr-associated protein
THEYE_A0635	COG1337	RAMP superfamily
THEYE_A0640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THEYE_A0642	COG0419	ATPase involved in DNA repair
THEYE_A0643	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEYE_A0644	COG1518	maintenance of DNA repeat elements
THEYE_A0646	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEYE_A0648	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
THEYE_A0650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THEYE_A0651	COG1183	phosphatidylcholine synthase activity
THEYE_A0652	COG0688	phosphatidylethanolamine metabolic process
THEYE_A0653	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
THEYE_A0654	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THEYE_A0655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THEYE_A0656	COG0802	atpase or kinase
THEYE_A0657	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THEYE_A0658	COG1573	uracil-dna glycosylase
THEYE_A0660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
THEYE_A0661	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THEYE_A0662	COG0123	including yeast histone deacetylase and acetoin utilization protein
THEYE_A0665	COG1139	Iron-sulfur cluster binding protein
THEYE_A0667	COG0247	lactate metabolic process
THEYE_A0668	COG0277	FAD linked oxidase domain protein
THEYE_A0669	COG1620	l-lactate permease
THEYE_A0670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THEYE_A0671	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THEYE_A0672	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
THEYE_A0673	COG0302	gtp cyclohydrolase
THEYE_A0674	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THEYE_A0677	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THEYE_A0678	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
THEYE_A0681	COG1937	Protein conserved in bacteria
THEYE_A0683	COG0493	'glutamate synthase
THEYE_A0683	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
THEYE_A0686	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
THEYE_A0687	COG0556	nucleotide-excision repair
THEYE_A0690	COG0113	porphobilinogen synthase activity
THEYE_A0692	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
THEYE_A0693	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THEYE_A0696	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THEYE_A0697	COG0195	Participates in both transcription termination and antitermination
THEYE_A0698	COG0779	Required for maturation of 30S ribosomal subunits
THEYE_A0703	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THEYE_A0704	COG0196	riboflavin kinase activity
THEYE_A0705	COG0237	dephospho-CoA kinase activity
THEYE_A0706	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THEYE_A0712	COG0784	Response regulator, receiver
THEYE_A0712	COG4191	Histidine kinase
THEYE_A0716	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
THEYE_A0717	COG0181	hydroxymethylbilane synthase activity
THEYE_A0724	COG4191	Histidine kinase
THEYE_A0725	COG2204	response regulator
THEYE_A0726	COG0469	pyruvate kinase activity
THEYE_A0727	COG2188	Transcriptional regulator
THEYE_A0732	COG0589	response to stress
THEYE_A0733	COG2204	response regulator
THEYE_A0735	COG2189	Belongs to the N(4) N(6)-methyltransferase family
THEYE_A0739	COG0745	RESPONSE REGULATOR receiver
THEYE_A0741	COG2204	response regulator
THEYE_A0742	COG5002	protein histidine kinase activity
THEYE_A0743	COG2204	response regulator
THEYE_A0744	COG3852	Histidine kinase
THEYE_A0747	COG4191	Histidine kinase
THEYE_A0749	COG0586	Pfam SNARE associated Golgi protein
THEYE_A0751	COG5002	protein histidine kinase activity
THEYE_A0752	COG0745	RESPONSE REGULATOR receiver
THEYE_A0755	COG1131	(ABC) transporter
THEYE_A0758	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THEYE_A0761	COG0730	response to heat
THEYE_A0762	COG0589	response to stress
THEYE_A0765	COG0411	ABC transporter
THEYE_A0774	COG1459	type II secretion system
THEYE_A0775	COG0501	Belongs to the peptidase M48B family
THEYE_A0777	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
THEYE_A0780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
THEYE_A0782	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
THEYE_A0785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THEYE_A0786	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
THEYE_A0786	COG0140	phosphoribosyl-ATP diphosphatase activity
THEYE_A0787	COG0537	adenosine 5'-monophosphoramidase activity
THEYE_A0790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
THEYE_A0791	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THEYE_A0794	COG0629	single-stranded DNA binding
THEYE_A0795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THEYE_A0799	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
THEYE_A0802	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THEYE_A0803	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THEYE_A0804	COG0742	ribosomal rna small subunit methyltransferase
THEYE_A0805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
THEYE_A0806	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
THEYE_A0807	COG0535	radical SAM domain protein
THEYE_A0808	COG0733	neurotransmitter:sodium symporter activity
THEYE_A0809	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THEYE_A0810	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
THEYE_A0811	COG1597	lipid kinase activity
THEYE_A0813	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
THEYE_A0817	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THEYE_A0818	COG0228	four-way junction DNA binding
THEYE_A0819	COG1837	Belongs to the UPF0109 family
THEYE_A0820	COG0336	Belongs to the RNA methyltransferase TrmD family
THEYE_A0821	COG0335	large ribosomal subunit rRNA binding
THEYE_A0822	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THEYE_A0823	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
THEYE_A0825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
THEYE_A0826	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THEYE_A0826	COG1519	Transferase
THEYE_A0827	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THEYE_A0830	COG1648	precorrin-2 dehydrogenase activity
THEYE_A0830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
THEYE_A0836	COG2801	Transposase and inactivated derivatives
THEYE_A0840	COG0501	Belongs to the peptidase M48B family
THEYE_A0841	COG1254	Belongs to the acylphosphatase family
THEYE_A0844	COG2801	Transposase and inactivated derivatives
THEYE_A0845	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
THEYE_A0845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THEYE_A0850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THEYE_A0852	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THEYE_A0855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THEYE_A0857	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEYE_A0858	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
THEYE_A0859	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THEYE_A0860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
THEYE_A0862	COG0129	dihydroxy-acid dehydratase activity
THEYE_A0867	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THEYE_A0868	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THEYE_A0869	COG1480	7TM receptor with intracellular HD hydrolase
THEYE_A0872	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
THEYE_A0873	COG2385	sporulation resulting in formation of a cellular spore
THEYE_A0875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
THEYE_A0876	COG2255	four-way junction helicase activity
THEYE_A0877	COG0632	four-way junction helicase activity
THEYE_A0878	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
THEYE_A0879	COG1127	ABC transporter
THEYE_A0884	COG0525	valine-tRNA ligase activity
THEYE_A0886	COG0157	Belongs to the NadC ModD family
THEYE_A0887	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
THEYE_A0888	COG4191	Histidine kinase
THEYE_A0893	COG0437	4 iron, 4 sulfur cluster binding
THEYE_A0894a	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THEYE_A0895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THEYE_A0896	COG0037	tRNA processing
THEYE_A0898	COG0583	DNA-binding transcription factor activity
THEYE_A0900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THEYE_A0901	COG0805	protein transport
THEYE_A0903	COG0012	GTP binding
THEYE_A0907	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THEYE_A0908	COG1144	Oxidoreductase
THEYE_A0909	COG0674	pyruvate-flavodoxin oxidoreductase activity
THEYE_A0910	COG1013	pyruvate-flavodoxin oxidoreductase activity
THEYE_A0911	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A0912	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A0913	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A0914	COG0649	NAD binding
THEYE_A0915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THEYE_A0916	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A0917	COG0839	Belongs to the complex I subunit 6 family
THEYE_A0918	COG0713	ATP synthesis coupled electron transport
THEYE_A0921	COG1007	ATP synthesis coupled electron transport
THEYE_A0927	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
THEYE_A0928	COG0601	transmembrane transport
THEYE_A0929	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THEYE_A0930	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
THEYE_A0931	COG0312	modulator of DNA gyrase
THEYE_A0932	COG0497	DNA recombination
THEYE_A0933	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THEYE_A0934	COG0778	Nitroreductase
THEYE_A0936	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THEYE_A0937	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
THEYE_A0938	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THEYE_A0939	COG1040	competence protein
THEYE_A0940	COG0730	response to heat
THEYE_A0942	COG1331	Highly conserved protein containing a thioredoxin domain
THEYE_A0943	COG0135	phosphoribosylanthranilate isomerase activity
THEYE_A0945	COG0859	PFAM glycosyl transferase family 9
THEYE_A0946	COG0131	Imidazoleglycerol-phosphate dehydratase
THEYE_A0946	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
THEYE_A0948	COG4608	Belongs to the ABC transporter superfamily
THEYE_A0954	COG3959	Transketolase, thiamine diphosphate binding domain
THEYE_A0954a	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THEYE_A0955	COG3876	Protein conserved in bacteria
THEYE_A0956	COG0823	Involved in the tonB-independent uptake of proteins
THEYE_A0960	COG0501	Belongs to the peptidase M48B family
THEYE_A0961	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THEYE_A0966	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THEYE_A0966	COG1918	ferrous iron import across plasma membrane
THEYE_A0968	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
THEYE_A0970	COG0131	Imidazoleglycerol-phosphate dehydratase
THEYE_A0971	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THEYE_A0972	COG0483	inositol monophosphate 1-phosphatase activity
THEYE_A0975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
THEYE_A0977	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
THEYE_A0979	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
THEYE_A0981	COG0163	prenyltransferase activity
THEYE_A0982	COG2084	Dehydrogenase
THEYE_A0983	COG1013	pyruvate-flavodoxin oxidoreductase activity
THEYE_A0984	COG0674	pyruvate-flavodoxin oxidoreductase activity
THEYE_A0984	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THEYE_A0988	COG3260	NADH ubiquinone oxidoreductase 20
THEYE_A0989	COG0651	ATP synthesis coupled electron transport
THEYE_A0991	COG0650	Formate hydrogenlyase subunit 4
THEYE_A0992	COG0651	ATP synthesis coupled electron transport
THEYE_A0993	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THEYE_A0995	COG3261	NADH dehydrogenase
THEYE_A0995	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
THEYE_A0998	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
THEYE_A1004	COG0148	phosphopyruvate hydratase activity
THEYE_A1006	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
THEYE_A1007	COG0509	glycine decarboxylation via glycine cleavage system
THEYE_A1008	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THEYE_A1010	COG0009	L-threonylcarbamoyladenylate synthase
THEYE_A1013	COG0714	Associated with various cellular activities
THEYE_A1014	COG1227	inorganic diphosphatase activity
THEYE_A1015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
THEYE_A1015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THEYE_A1018	COG1765	OsmC-like protein
THEYE_A1019	COG0409	Hydrogenase expression formation protein
THEYE_A1021	COG0653	protein targeting
THEYE_A1024	COG1063	alcohol dehydrogenase
THEYE_A1026	COG0828	Belongs to the bacterial ribosomal protein bS21 family
THEYE_A1028	COG0358	DNA primase activity
THEYE_A1032	COG0328	RNA-DNA hybrid ribonuclease activity
THEYE_A1033	COG0037	tRNA processing
THEYE_A1037	COG0564	pseudouridine synthase activity
THEYE_A1038	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THEYE_A1041	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THEYE_A1046	COG0248	Ppx GppA phosphatase
THEYE_A1047	COG0442	prolyl-tRNA aminoacylation
THEYE_A1048	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEYE_A1049	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THEYE_A1051	COG0655	NAD(P)H dehydrogenase (quinone) activity
THEYE_A1052	COG1408	metallophosphoesterase
THEYE_A1053	COG0450	alkyl hydroperoxide reductase
THEYE_A1057	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
THEYE_A1060	COG1333	cytochrome c biogenesis protein
THEYE_A1061	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THEYE_A1062	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THEYE_A1063	COG0137	argininosuccinate synthase activity
THEYE_A1064	COG0758	DNA mediated transformation
THEYE_A1064	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THEYE_A1066	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
THEYE_A1068	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THEYE_A1069	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THEYE_A1070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
THEYE_A1071	COG1426	Protein conserved in bacteria
THEYE_A1072	COG0557	exoribonuclease II activity
THEYE_A1074	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
THEYE_A1074	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
THEYE_A1075	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
THEYE_A1078	COG1598	PFAM Uncharacterised protein family UPF0150
THEYE_A1080	COG1120	ATPase activity
THEYE_A1081	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
THEYE_A1086	COG1720	tRNA m6t6A37 methyltransferase activity
THEYE_A1101	COG1518	maintenance of DNA repeat elements
THEYE_A1102a	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEYE_A1106	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THEYE_A1109	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THEYE_A1111	COG3852	Histidine kinase
THEYE_A1112	COG2204	response regulator
THEYE_A1113	COG0840	transmembrane signaling receptor activity
THEYE_A1114	COG1007	ATP synthesis coupled electron transport
THEYE_A1115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A1116	COG0651	ATP synthesis coupled electron transport
THEYE_A1118	COG0651	ATP synthesis coupled electron transport
THEYE_A1119	COG0713	ATP synthesis coupled electron transport
THEYE_A1121	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THEYE_A1123	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A1125	COG0649	NAD binding
THEYE_A1126	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THEYE_A1127	COG0437	4 iron, 4 sulfur cluster binding
THEYE_A1131	COG0589	response to stress
THEYE_A1132	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THEYE_A1133	COG0019	diaminopimelate decarboxylase activity
THEYE_A1134	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
THEYE_A1137	COG1074	ATP-dependent DNA helicase activity
THEYE_A1138	COG0574	Belongs to the PEP-utilizing enzyme family
THEYE_A1138	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THEYE_A1139	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
THEYE_A1140	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
THEYE_A1144	COG0149	triose-phosphate isomerase activity
THEYE_A1148	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
THEYE_A1150	COG0154	amidase activity
THEYE_A1151	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THEYE_A1155	COG3301	Polysulphide reductase, NrfD
THEYE_A1156	COG0437	4 iron, 4 sulfur cluster binding
THEYE_A1161	COG0415	Belongs to the DNA photolyase family
THEYE_A1168	COG1054	Belongs to the UPF0176 family
THEYE_A1173	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
THEYE_A1175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THEYE_A1177	COG1492	cobalamin metabolic process
THEYE_A1178	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
THEYE_A1182	COG4771	TonB-dependent receptor
THEYE_A1184	COG2361	Protein of unknown function DUF86
THEYE_A1186	COG2003	Belongs to the UPF0758 family
THEYE_A1193	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THEYE_A1196	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
THEYE_A1197	COG0574	Belongs to the PEP-utilizing enzyme family
THEYE_A1197	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THEYE_A1198	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THEYE_A1199	COG0011	TIGRFAM Protein of
THEYE_A1202	COG0521	Mo-molybdopterin cofactor biosynthetic process
THEYE_A1203	COG0785	Cytochrome C biogenesis protein
THEYE_A1204	COG0495	leucyl-tRNA aminoacylation
THEYE_A1210	COG1466	dna polymerase III delta subunit
THEYE_A1213	COG0402	S-adenosylhomocysteine deaminase activity
THEYE_A1217	COG2801	Transposase and inactivated derivatives
THEYE_A1223	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THEYE_A1224	COG0706	membrane insertase activity
THEYE_A1225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
THEYE_A1226	COG0230	Belongs to the bacterial ribosomal protein bL34 family
THEYE_A1227	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THEYE_A1228	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THEYE_A1229	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THEYE_A1230	COG1136	(ABC) transporter
THEYE_A1233	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THEYE_A1238	COG0540	Belongs to the ATCase OTCase family
THEYE_A1239	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THEYE_A1240	COG0505	Belongs to the CarA family
THEYE_A1242	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
THEYE_A1243	COG0138	bifunctional purine biosynthesis protein purh
THEYE_A1245	COG0151	Belongs to the GarS family
THEYE_A1247	COG0784	Response regulator, receiver
THEYE_A1247	COG4191	Histidine kinase
THEYE_A1250	COG1131	(ABC) transporter
THEYE_A1252	COG0315	cyclic pyranopterin monophosphate synthase activity
THEYE_A1253	COG4221	oxidoreductase activity
THEYE_A1254	COG2814	Major facilitator Superfamily
THEYE_A1255	COG0268	Binds directly to 16S ribosomal RNA
THEYE_A1256	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
THEYE_A1257	COG0058	SHG alpha-glucan phosphorylase activity
THEYE_A1260	COG0084	hydrolase, TatD family'
THEYE_A1261	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
THEYE_A1263	COG1295	ribonuclease BN
THEYE_A1264	COG0351	phosphomethylpyrimidine kinase
THEYE_A1265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
THEYE_A1266	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
THEYE_A1275	COG0028	Belongs to the TPP enzyme family
THEYE_A1276	COG0440	acetolactate synthase activity
THEYE_A1278	COG0473	3-isopropylmalate dehydrogenase activity
THEYE_A1279	COG1253	flavin adenine dinucleotide binding
THEYE_A1280	COG5557	Pfam Polysulphide reductase, NrfD
THEYE_A1281	COG3064	Membrane
THEYE_A1281	COG0437	4 iron, 4 sulfur cluster binding
THEYE_A1284	COG0247	lactate metabolic process
THEYE_A1285	COG2181	nitrate reductase activity
THEYE_A1288	COG0641	radical SAM
THEYE_A1291	COG1918	ferrous iron import across plasma membrane
THEYE_A1291	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THEYE_A1293	COG2078	PFAM AMMECR1 domain protein
THEYE_A1296	COG1376	ErfK ybiS ycfS ynhG family protein
THEYE_A1298	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THEYE_A1298	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THEYE_A1299	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
THEYE_A1300	COG1388	LysM domain
THEYE_A1300	COG0791	NLP P60 protein
THEYE_A1301	COG1910	domain protein
THEYE_A1303	COG1858	cytochrome C peroxidase
THEYE_A1307	COG1271	oxidase subunit
THEYE_A1308	COG1294	oxidase, subunit
THEYE_A1309	COG1959	2 iron, 2 sulfur cluster binding
THEYE_A1312	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
THEYE_A1313	COG1104	cysteine desulfurase activity
THEYE_A1316	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THEYE_A1319	COG1181	Belongs to the D-alanine--D-alanine ligase family
THEYE_A1320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
THEYE_A1321	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THEYE_A1322	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THEYE_A1323	COG0772	Belongs to the SEDS family
THEYE_A1326	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THEYE_A1327	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THEYE_A1329	COG0768	penicillin binding
THEYE_A1331	COG0275	rRNA processing
THEYE_A1332	COG2001	Belongs to the MraZ family
THEYE_A1333	COG0156	8-amino-7-oxononanoate synthase activity
THEYE_A1334	COG1472	Belongs to the glycosyl hydrolase 3 family
THEYE_A1335	COG2223	nitrite transmembrane transporter activity
THEYE_A1337	COG0745	RESPONSE REGULATOR receiver
THEYE_A1338	COG0784	Response regulator, receiver
THEYE_A1341	COG1692	metallophosphoesterase
THEYE_A1342	COG1418	mRNA catabolic process
THEYE_A1344	COG0417	DNA replication proofreading
THEYE_A1346	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THEYE_A1347	COG0085	RNA polymerase activity
THEYE_A1348	COG0222	ribosome binding
THEYE_A1349	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THEYE_A1350	COG0081	regulation of translation
THEYE_A1355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THEYE_A1366	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
THEYE_A1374	COG0589	response to stress
THEYE_A1375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A1376	COG1160	GTP binding
THEYE_A1377	COG2204	response regulator
THEYE_A1378	COG5000	phosphorelay sensor kinase activity
THEYE_A1381	COG0730	response to heat
THEYE_A1384	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
THEYE_A1385	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
THEYE_A1386	COG0698	ribose 5-phosphate isomerase
THEYE_A1387	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THEYE_A1388	COG0590	tRNA wobble adenosine to inosine editing
THEYE_A1389	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
THEYE_A1390	COG0375	protein maturation
THEYE_A1394	COG1260	myo-inositol-1-phosphate synthase
THEYE_A1395	COG4974	Belongs to the 'phage' integrase family
THEYE_A1396	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THEYE_A1397	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THEYE_A1398	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
THEYE_A1400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THEYE_A1402	COG0745	RESPONSE REGULATOR receiver
THEYE_A1403	COG2205	protein histidine kinase activity
THEYE_A1407	COG0577	efflux transmembrane transporter activity
THEYE_A1407	COG1136	(ABC) transporter
THEYE_A1408	COG1136	(ABC) transporter
THEYE_A1408	COG0577	efflux transmembrane transporter activity
THEYE_A1416	COG0072	phenylalanine-tRNA ligase activity
THEYE_A1417	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THEYE_A1418	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THEYE_A1420	COG0203	ribosomal protein L17
THEYE_A1421	COG0202	RNA polymerase activity
THEYE_A1422	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THEYE_A1423	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THEYE_A1424	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THEYE_A1426	COG0024	Methionine aminopeptidase
THEYE_A1427	COG0201	protein transport
THEYE_A1428	COG0200	Binds to the 23S rRNA
THEYE_A1429	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THEYE_A1430	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THEYE_A1431	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THEYE_A1432	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THEYE_A1433	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THEYE_A1435	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THEYE_A1436	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THEYE_A1437	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THEYE_A1438	COG0255	Belongs to the universal ribosomal protein uL29 family
THEYE_A1439	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THEYE_A1440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THEYE_A1441	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
THEYE_A1442	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THEYE_A1443	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THEYE_A1444	COG0089	rRNA binding
THEYE_A1445	COG0088	Forms part of the polypeptide exit tunnel
THEYE_A1447	COG0051	transcription antitermination factor activity, RNA binding
THEYE_A1448	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THEYE_A1449	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THEYE_A1450	COG0049	tRNA binding
THEYE_A1451	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THEYE_A1453	COG0193	aminoacyl-tRNA hydrolase activity
THEYE_A1454	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THEYE_A1455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
THEYE_A1457	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
THEYE_A1461	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
THEYE_A1463	COG0628	permease
THEYE_A1464	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
THEYE_A1465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
THEYE_A1466	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
THEYE_A1467	COG0860	N-Acetylmuramoyl-L-alanine amidase
THEYE_A1475	COG0330	HflC and HflK could
THEYE_A1477	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THEYE_A1478	COG0416	fatty acid biosynthetic process
THEYE_A1479	COG0333	Belongs to the bacterial ribosomal protein bL32 family
THEYE_A1480	COG1399	metal-binding, possibly nucleic acid-binding protein
THEYE_A1481	COG0793	Belongs to the peptidase S41A family
THEYE_A1483	COG2177	Part of the ABC transporter FtsEX involved in
THEYE_A1484	COG2884	Cell division ATP-binding protein ftsE
THEYE_A1485	COG3958	Transketolase
THEYE_A1486	COG3959	Transketolase, thiamine diphosphate binding domain
THEYE_A1487	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THEYE_A1487	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THEYE_A1488	COG0612	Peptidase, M16
THEYE_A1489	COG0612	Peptidase, M16
THEYE_A1490	COG0745	RESPONSE REGULATOR receiver
THEYE_A1491	COG5002	protein histidine kinase activity
THEYE_A1492	COG0297	glycogen (starch) synthase activity
THEYE_A1495	COG3852	Histidine kinase
THEYE_A1496	COG2204	response regulator
THEYE_A1497	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
THEYE_A1498	COG0644	oxidoreductase
THEYE_A1498	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
THEYE_A1499	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THEYE_A1500	COG0142	geranyltranstransferase activity
THEYE_A1501	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
THEYE_A1506	COG0425	Belongs to the sulfur carrier protein TusA family
THEYE_A1509	COG1516	flagellar protein fliS
THEYE_A1510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
THEYE_A1515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THEYE_A1516	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THEYE_A1519	COG3959	Transketolase, thiamine diphosphate binding domain
THEYE_A1520	COG3958	Transketolase
THEYE_A1522	COG0527	aspartate kinase activity
THEYE_A1523	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
THEYE_A1524	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
THEYE_A1526	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
THEYE_A1529	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THEYE_A1530	COG0356	it plays a direct role in the translocation of protons across the membrane
THEYE_A1532	COG0602	queuosine metabolic process
THEYE_A1533	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THEYE_A1535	COG1496	oxidoreductase activity
THEYE_A1537	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THEYE_A1540	COG3706	GGDEF domain
THEYE_A1541	COG0052	Belongs to the universal ribosomal protein uS2 family
THEYE_A1542	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THEYE_A1543	COG0528	UMP kinase activity
THEYE_A1544	COG0233	cytoplasmic translational termination
THEYE_A1545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THEYE_A1546	COG0101	tRNA pseudouridine synthase activity
THEYE_A1548	COG0859	PFAM glycosyl transferase family 9
THEYE_A1549	COG0438	transferase activity, transferring glycosyl groups
THEYE_A1550	COG0726	polysaccharide deacetylase
THEYE_A1552	COG3620	sequence-specific DNA binding
THEYE_A1552	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
THEYE_A1552	COG0617	tRNA 3'-terminal CCA addition
THEYE_A1554	COG3547	Transposase (IS116 IS110 IS902 family)
THEYE_A1557	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THEYE_A1559	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
THEYE_A1565	COG1309	transcriptional regulator
THEYE_A1566	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THEYE_A1567	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
THEYE_A1571	COG0842	Transport permease protein
THEYE_A1572	COG1129	ABC transporter
THEYE_A1572	COG0842	Transport permease protein
THEYE_A1575	COG1131	(ABC) transporter
THEYE_A1576	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THEYE_A1582	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THEYE_A1583	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THEYE_A1584	COG2086	electron transfer activity
THEYE_A1585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
THEYE_A1586	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THEYE_A1587	COG0039	L-malate dehydrogenase activity
THEYE_A1588	COG0105	UTP biosynthetic process
THEYE_A1589	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
THEYE_A1590	COG1966	Carbon starvation protein
THEYE_A1591	COG3279	Response regulator of the LytR AlgR family
THEYE_A1592	COG3275	phosphorelay sensor kinase activity
THEYE_A1594	COG1131	(ABC) transporter
THEYE_A1596	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
THEYE_A1597	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THEYE_A1599	COG1773	rubredoxin
THEYE_A1600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
THEYE_A1601	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
THEYE_A1604	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THEYE_A1605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
THEYE_A1606	COG0799	negative regulation of ribosome biogenesis
THEYE_A1608	COG0644	oxidoreductase
THEYE_A1612	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THEYE_A1617	COG1309	transcriptional regulator
THEYE_A1618	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THEYE_A1619	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
THEYE_A1623	COG0842	Transport permease protein
THEYE_A1624	COG1129	ABC transporter
THEYE_A1624	COG0842	Transport permease protein
THEYE_A1627	COG1131	(ABC) transporter
THEYE_A1628	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THEYE_A1634	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THEYE_A1635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THEYE_A1636	COG2086	electron transfer activity
THEYE_A1637	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
THEYE_A1638	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THEYE_A1639	COG0039	L-malate dehydrogenase activity
THEYE_A1640	COG0105	UTP biosynthetic process
THEYE_A1641	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
THEYE_A1642	COG1966	Carbon starvation protein
THEYE_A1643	COG3279	Response regulator of the LytR AlgR family
THEYE_A1644	COG3275	phosphorelay sensor kinase activity
THEYE_A1646	COG1131	(ABC) transporter
THEYE_A1648	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
THEYE_A1649	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THEYE_A1651	COG1773	rubredoxin
THEYE_A1652	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
THEYE_A1653	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
THEYE_A1656	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THEYE_A1657	COG1385	rRNA (uridine-N3-)-methyltransferase activity
THEYE_A1658	COG0799	negative regulation of ribosome biogenesis
THEYE_A1659a	COG0644	oxidoreductase
THEYE_A1664	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
THEYE_A1671	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
THEYE_A1672	COG1570	exodeoxyribonuclease VII activity
THEYE_A1674	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
THEYE_A1676	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
THEYE_A1677	COG1127	ABC transporter
THEYE_A1678	COG0133	tryptophan synthase activity
THEYE_A1679	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
THEYE_A1681	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THEYE_A1682	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
THEYE_A1683	COG0586	Pfam SNARE associated Golgi protein
THEYE_A1685	COG0174	glutamine synthetase
THEYE_A1688	COG0493	'glutamate synthase
THEYE_A1689	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
THEYE_A1692	COG0732	type I restriction modification DNA specificity domain
THEYE_A1693	COG0732	type I restriction modification DNA specificity domain
THEYE_A1694	COG1196	nuclear chromosome segregation
THEYE_A1697	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
THEYE_A1699	COG2414	aldehyde ferredoxin oxidoreductase
THEYE_A1702	COG0519	Catalyzes the synthesis of GMP from XMP
THEYE_A1706	COG0347	Belongs to the P(II) protein family
THEYE_A1707	COG0004	ammonium transporteR
THEYE_A1711	COG0347	Belongs to the P(II) protein family
THEYE_A1712	COG0347	Belongs to the P(II) protein family
THEYE_A1714	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
THEYE_A1715	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
THEYE_A1716	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
THEYE_A1717	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
THEYE_A1718	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THEYE_A1719	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THEYE_A1722	COG1027	Aspartate ammonia-lyase
THEYE_A1726	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
THEYE_A1726	COG4624	Iron only hydrogenase large subunit, C-terminal domain
THEYE_A1729	COG2877	3-deoxy-8-phosphooctulonate synthase activity
THEYE_A1731	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
THEYE_A1735	COG0180	Tryptophanyl-tRNA synthetase
THEYE_A1736	COG1994	Peptidase M50
THEYE_A1737	COG0511	ligase activity, forming carbon-carbon bonds
THEYE_A1737	COG5016	pyruvate
THEYE_A1738	COG0439	Biotin carboxylase
THEYE_A1741	COG3409	Peptidoglycan-binding domain 1 protein
THEYE_A1741	COG0793	Belongs to the peptidase S41A family
THEYE_A1742	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
THEYE_A1745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
THEYE_A1747	COG0492	ferredoxin-NADP+ reductase activity
THEYE_A1753	COG1067	ATP-dependent peptidase activity
THEYE_A1754	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THEYE_A1755	COG1121	(ABC) transporter
THEYE_A1757	COG0484	heat shock protein binding
THEYE_A1758	COG0443	Heat shock 70 kDa protein
THEYE_A1759	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THEYE_A1760	COG1420	regulation of RNA biosynthetic process
THEYE_A1761	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THEYE_A1762	COG0019	diaminopimelate decarboxylase activity
THEYE_A1763	COG1605	Chorismate mutase
THEYE_A1763	COG0077	Prephenate dehydratase
THEYE_A1764	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THEYE_A1765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
THEYE_A1766	COG0287	Prephenate dehydrogenase
THEYE_A1767	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THEYE_A1768	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
THEYE_A1769	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
THEYE_A1771	COG0616	signal peptide processing
THEYE_A1772	COG0776	regulation of translation
THEYE_A1773	COG0444	Belongs to the ABC transporter superfamily
THEYE_A1774	COG0704	Plays a role in the regulation of phosphate uptake
THEYE_A1778	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
THEYE_A1779	COG0710	3-dehydroquinate dehydratase activity
THEYE_A1780	COG0745	RESPONSE REGULATOR receiver
THEYE_A1785	COG2200	EAL domain
THEYE_A1788	COG2205	protein histidine kinase activity
THEYE_A1788	COG0784	Response regulator, receiver
THEYE_A1789	COG2723	6-phospho-beta-galactosidase activity
THEYE_A1790	COG0573	inorganic phosphate transmembrane transporter activity
THEYE_A1791	COG0581	inorganic phosphate transmembrane transporter activity
THEYE_A1792	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THEYE_A1795	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
THEYE_A1795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
THEYE_A1796	COG0124	histidyl-tRNA synthetase
THEYE_A1797	COG3599	regulation of cell shape
THEYE_A1799	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
THEYE_A1800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
THEYE_A1801	COG5000	phosphorelay sensor kinase activity
THEYE_A1802	COG2204	response regulator
THEYE_A1808	COG0306	phosphate transporter
THEYE_A1813	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THEYE_A1815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
THEYE_A1816	COG3158	transport of potassium into the cell
THEYE_A1817	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
THEYE_A1820	COG1324	tolerance protein
THEYE_A1821	COG4274	PFAM GYD family protein
THEYE_A1824	COG0420	3'-5' exonuclease activity
THEYE_A1826	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THEYE_A1827	COG1185	polyribonucleotide nucleotidyltransferase activity
THEYE_A1828	COG0612	Peptidase, M16
THEYE_A1830	COG1233	COG1233 Phytoene dehydrogenase and related
THEYE_A1835	COG2046	Belongs to the sulfate adenylyltransferase family
THEYE_A1836	COG0563	adenylate kinase activity
THEYE_A1837	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THEYE_A1839	COG0552	protein localization to endoplasmic reticulum
THEYE_A1843	COG1792	Involved in formation and maintenance of cell shape
THEYE_A1845	COG0768	penicillin binding
THEYE_A1846	COG0772	Belongs to the SEDS family
THEYE_A1847	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
THEYE_A1848	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THEYE_A1854	COG3259	Nickel-dependent hydrogenase
THEYE_A1858	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
THEYE_A1860	COG0489	protein tyrosine kinase activity
THEYE_A1865	COG0735	belongs to the Fur family
THEYE_A1866	COG0730	response to heat
THEYE_A1868	COG0217	transcriptional regulatory protein
THEYE_A1870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THEYE_A1871	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THEYE_A1873	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THEYE_A1874	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
THEYE_A1875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
THEYE_A1877	COG1011	Hydrolase
THEYE_A1883	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THEYE_A1884	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THEYE_A1885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THEYE_A1887	COG1192	Involved in chromosome partitioning
THEYE_A1889	COG0322	excinuclease ABC activity
THEYE_A1894	COG1127	ABC transporter
THEYE_A1917	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THEYE_A1920	COG0310	cobalt ion transport
THEYE_A1921	COG0310	cobalt ion transport
THEYE_A1922	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
THEYE_A1923	COG1122	ATPase activity
THEYE_A1924	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THEYE_A1925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
THEYE_A1926	COG3118	belongs to the thioredoxin family
THEYE_A1928	COG0542	response to heat
THEYE_A1930	COG0484	heat shock protein binding
THEYE_A1932	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
THEYE_A1936	COG0284	orotidine-5'-phosphate decarboxylase activity
THEYE_A1937	COG0717	Belongs to the dCTP deaminase family
THEYE_A1940	COG0298	carbon dioxide binding
THEYE_A1942	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
THEYE_A1947	COG2361	Protein of unknown function DUF86
THEYE_A1948	COG0205	6-phosphofructokinase activity
THEYE_A1950	COG0792	nuclease activity
THEYE_A1955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
THEYE_A1958	COG0107	imidazoleglycerol-phosphate synthase activity
THEYE_A1959	COG1966	Carbon starvation protein
THEYE_A1961	COG0579	oxidoreductase
THEYE_A1964	COG1715	Restriction endonuclease
THEYE_A1968	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
THEYE_A1969	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THEYE_A1970	COG0668	transmembrane transport
THEYE_A1975	COG0215	cysteine-tRNA ligase activity
THEYE_A1976	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
THEYE_A1977	COG2217	Heavy metal translocating P-type atpase
THEYE_A1979	COG1968	undecaprenyl-diphosphatase activity
THEYE_A1980	COG1674	ftsk spoiiie
THEYE_A1983	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
THEYE_A1984	COG1979	alcohol dehydrogenase
THEYE_A1985	COG0436	Aminotransferase
THEYE_A1987	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
THEYE_A1989	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
THEYE_A1990	COG1192	Involved in chromosome partitioning
THEYE_A1991	COG1475	DNA binding
THEYE_A1992	COG0277	FAD linked oxidase domain protein
THEYE_A1993	COG1196	nuclear chromosome segregation
THEYE_A1994	COG2221	Nitrite and sulphite reductase 4Fe-4S
THEYE_A1995	COG2221	Nitrite and sulphite reductase 4Fe-4S
THEYE_A1997	COG1546	Belongs to the CinA family
THEYE_A1997	COG1058	Belongs to the CinA family
THEYE_A2000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THEYE_A2001	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THEYE_A2002	COG2835	tetraacyldisaccharide 4'-kinase activity
THEYE_A2003	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THEYE_A2004	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
THEYE_A2006	COG2199	diguanylate cyclase activity
THEYE_A2006	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THEYE_A2034	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
THEYE_A2036	COG1518	maintenance of DNA repeat elements
THEYE_A2045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
THEYE_A2050	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
THEYE_A2051	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
THEYE_A2053	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THEYE_A2057	COG0739	heme binding
THEYE_A2058	COG1706	bacterial-type flagellum-dependent cell motility
THEYE_A2059	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
THEYE_A2065	COG2201	protein-glutamate methylesterase activity
THEYE_A2066	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
THEYE_A2067	COG0643	Histidine kinase
THEYE_A2067	COG0784	Response regulator, receiver
THEYE_A2067	COG2198	Histidine kinase
THEYE_A2068	COG0745	RESPONSE REGULATOR receiver
THEYE_A2069	COG0745	RESPONSE REGULATOR receiver
THEYE_A2070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
THEYE_A2075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THEYE_A2076	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THEYE_A2077	COG1684	flagellar biosynthetic protein fliR
THEYE_A2078	COG1987	bacterial-type flagellum assembly
THEYE_A2079	COG3190	flagellar
THEYE_A2079	COG1338	Plays a role in the flagellum-specific transport system
THEYE_A2082	COG1580	Controls the rotational direction of flagella during chemotaxis
THEYE_A2083	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THEYE_A2088	COG0546	phosphoglycolate phosphatase activity
THEYE_A2089	COG2894	cell division
THEYE_A2090	COG3956	TIGRFAM MazG family protein
THEYE_A2094	COG1132	(ABC) transporter
THEYE_A2095	COG0463	Glycosyl transferase, family 2
THEYE_A2096	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THEYE_A2098	COG2885	chlorophyll binding
THEYE_A2099	COG0751	glycine-tRNA ligase activity
THEYE_A2100	COG0752	glycyl-tRNA synthetase alpha subunit