locus-tag	class	description
TCARB_RS00015	COG0585	pseudouridine synthase activity
TCARB_RS00020	COG1444	tRNA N-acetyltransferase activity
TCARB_RS00030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TCARB_RS00095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TCARB_RS00100	COG0175	sulfate reduction
TCARB_RS00150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCARB_RS00175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TCARB_RS00195	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_RS00200	COG1122	ATPase activity
TCARB_RS00205	COG1122	ATPase activity
TCARB_RS00210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TCARB_RS00230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TCARB_RS00265	COG1192	Involved in chromosome partitioning
TCARB_RS00325	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TCARB_RS00385	COG2078	PFAM AMMECR1 domain protein
TCARB_RS00395	COG1793	dna ligase
TCARB_RS00415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TCARB_RS00440	COG0516	GMP reductase activity
TCARB_RS00440	COG0517	IMP dehydrogenase activity
TCARB_RS00450	COG0519	Catalyzes the synthesis of GMP from XMP
TCARB_RS00450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TCARB_RS00465	COG1254	Belongs to the acylphosphatase family
TCARB_RS00475	COG0303	'Molybdopterin
TCARB_RS00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TCARB_RS00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TCARB_RS00510	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TCARB_RS00520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TCARB_RS00525	COG2814	Major facilitator Superfamily
TCARB_RS00545	COG0310	cobalt ion transport
TCARB_RS00560	COG0109	protoheme IX farnesyltransferase activity
TCARB_RS00595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TCARB_RS00600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TCARB_RS00610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_RS00625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCARB_RS00650	COG0126	phosphoglycerate kinase activity
TCARB_RS00675	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TCARB_RS00750	COG1573	uracil-dna glycosylase
TCARB_RS00790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_RS00815	COG2835	tetraacyldisaccharide 4'-kinase activity
TCARB_RS00820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TCARB_RS00855	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_RS00865	COG0438	transferase activity, transferring glycosyl groups
TCARB_RS00870	COG1449	Belongs to the glycosyl hydrolase 57 family
TCARB_RS00880	COG0442	prolyl-tRNA aminoacylation
TCARB_RS00885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TCARB_RS00890	COG1234	tRNA 3'-trailer cleavage
TCARB_RS00895	COG1082	Xylose isomerase domain protein TIM barrel
TCARB_RS00900	COG1063	alcohol dehydrogenase
TCARB_RS00905	COG1402	creatininase
TCARB_RS00910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_RS00915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TCARB_RS00925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_RS00930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TCARB_RS00955	COG0330	HflC and HflK could
TCARB_RS01000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCARB_RS01010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TCARB_RS01040	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TCARB_RS01060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TCARB_RS01060	COG0551	DNA topoisomerase type I activity
TCARB_RS01085	COG0149	triose-phosphate isomerase activity
TCARB_RS01135	COG2151	metal-sulfur cluster biosynthetic enzyme
TCARB_RS01150	COG2255	four-way junction helicase activity
TCARB_RS01170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCARB_RS01180	COG0513	Belongs to the DEAD box helicase family
TCARB_RS01185	COG2264	protein methyltransferase activity
TCARB_RS01190	COG0017	Asparaginyl-tRNA synthetase
TCARB_RS01210	COG2814	Major facilitator Superfamily
TCARB_RS01220	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TCARB_RS01240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCARB_RS01240	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS01275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TCARB_RS01295	COG1940	carbohydrate kinase activity
TCARB_RS01310	COG0215	cysteine-tRNA ligase activity
TCARB_RS01315	COG1454	alcohol dehydrogenase
TCARB_RS01320	COG1126	abc transporter atp-binding protein
TCARB_RS01325	COG0765	amino acid transport
TCARB_RS01350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TCARB_RS01355	COG1177	transmembrane transport
TCARB_RS01365	COG3842	ATPase activity
TCARB_RS01380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TCARB_RS01420	COG0037	tRNA processing
TCARB_RS01460	COG1201	RNA secondary structure unwinding
TCARB_RS01545	COG1918	ferrous iron import across plasma membrane
TCARB_RS01545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TCARB_RS01580	COG0656	L-ascorbic acid biosynthetic process
TCARB_RS01600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TCARB_RS01625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TCARB_RS01650	COG1487	ribonuclease activity
TCARB_RS01685	COG0673	inositol 2-dehydrogenase activity
TCARB_RS01690	COG1201	RNA secondary structure unwinding
TCARB_RS01745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TCARB_RS01750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TCARB_RS01825	COG0456	acetyltransferase
TCARB_RS01835	COG3260	NADH ubiquinone oxidoreductase 20
TCARB_RS01840	COG3261	NADH dehydrogenase
TCARB_RS01840	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TCARB_RS01850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_RS01865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_RS01870	COG0651	ATP synthesis coupled electron transport
TCARB_RS01880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_RS01885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_RS01890	COG0649	NAD binding
TCARB_RS01895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_RS01900	COG4656	Part of a membrane complex involved in electron transport
TCARB_RS01910	COG0713	ATP synthesis coupled electron transport
TCARB_RS01915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_RS01920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_RS01925	COG1007	ATP synthesis coupled electron transport
TCARB_RS01930	COG0174	glutamine synthetase
TCARB_RS01935	COG0693	protein deglycase activity
TCARB_RS01940	COG4821	SIS domain
TCARB_RS01945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_RS01960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCARB_RS01970	COG0673	inositol 2-dehydrogenase activity
TCARB_RS01980	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_RS01990	COG3716	PTS system mannose fructose sorbose family IID component
TCARB_RS01995	COG0561	phosphatase activity
TCARB_RS02000	COG3037	sugar-specific permease SgaT UlaA
TCARB_RS02010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TCARB_RS02015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TCARB_RS02030	COG1122	ATPase activity
TCARB_RS02045	COG2723	6-phospho-beta-galactosidase activity
TCARB_RS02055	COG1085	galactose-1-phosphate uridylyltransferase
TCARB_RS02090	COG0437	4 iron, 4 sulfur cluster binding
TCARB_RS02125	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TCARB_RS02150	COG0395	ABC-type sugar transport system, permease component
TCARB_RS02155	COG3842	ATPase activity
TCARB_RS02165	COG2431	L-lysine efflux transmembrane transporter activity
TCARB_RS02200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TCARB_RS02205	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_RS02210	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
TCARB_RS02215	COG3836	Belongs to the HpcH HpaI aldolase family
TCARB_RS02220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_RS02225	COG1070	Carbohydrate kinase
TCARB_RS02240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TCARB_RS02250	COG1175	transmembrane transport
TCARB_RS02255	COG0395	ABC-type sugar transport system, permease component
TCARB_RS02260	COG1070	Carbohydrate kinase
TCARB_RS02275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TCARB_RS02280	COG0540	Belongs to the ATCase OTCase family
TCARB_RS02285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TCARB_RS02290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TCARB_RS02295	COG0543	2 iron, 2 sulfur cluster binding
TCARB_RS02300	COG0167	dihydroorotate dehydrogenase activity
TCARB_RS02305	COG1418	mRNA catabolic process
TCARB_RS02315	COG0504	CTP synthase activity
TCARB_RS02320	COG3842	ATPase activity
TCARB_RS02340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TCARB_RS02355	COG1131	(ABC) transporter
TCARB_RS02375	COG3833	ABC-type maltose transport systems, permease component
TCARB_RS02380	COG3842	ATPase activity
TCARB_RS02390	COG2095	MarC family integral membrane protein
TCARB_RS02405	COG0543	2 iron, 2 sulfur cluster binding
TCARB_RS02410	COG0493	'glutamate synthase
TCARB_RS02410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TCARB_RS02440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TCARB_RS02490	COG0396	ATPase activity
TCARB_RS02510	COG4214	carbohydrate transport
TCARB_RS02555	COG0501	Belongs to the peptidase M48B family
TCARB_RS02575	COG1131	(ABC) transporter
TCARB_RS02605	COG0667	Aldo Keto reductase
TCARB_RS02610	COG1850	ribulose-bisphosphate carboxylase activity
TCARB_RS02620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_RS02630	COG0371	Dehydrogenase
TCARB_RS02680	COG0864	Transcriptional regulator
TCARB_RS02695	COG0277	FAD linked oxidase domain protein
TCARB_RS02710	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCARB_RS02710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TCARB_RS02720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TCARB_RS02755	COG1175	transmembrane transport
TCARB_RS02760	COG3833	ABC-type maltose transport systems, permease component
TCARB_RS02765	COG3842	ATPase activity
TCARB_RS02770	COG1378	Sugar-specific transcriptional regulator TrmB
TCARB_RS02785	COG1554	hydrolase, family 65, central catalytic
TCARB_RS02795	COG0778	Nitroreductase
TCARB_RS02810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TCARB_RS02815	COG1830	Aldolase
TCARB_RS02820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TCARB_RS02820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TCARB_RS02825	COG0805	protein transport
TCARB_RS02835	COG0805	protein transport
TCARB_RS02840	COG0454	-acetyltransferase
TCARB_RS02850	COG2095	MarC family integral membrane protein
TCARB_RS02855	COG2814	Major facilitator Superfamily
TCARB_RS02875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TCARB_RS02880	COG0747	negative chemotaxis
TCARB_RS02885	COG0601	transmembrane transport
TCARB_RS02895	COG0444	Belongs to the ABC transporter superfamily
TCARB_RS02900	COG4608	Belongs to the ABC transporter superfamily
TCARB_RS02915	COG0243	molybdopterin cofactor binding
TCARB_RS02950	COG0309	Hydrogenase expression formation protein (HypE)
TCARB_RS02980	COG1342	Belongs to the UPF0251 family
TCARB_RS03015	COG2211	Major facilitator Superfamily
TCARB_RS03045	COG0668	transmembrane transport
TCARB_RS03080	COG0395	ABC-type sugar transport system, permease component
TCARB_RS03120	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_RS03125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCARB_RS03150	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TCARB_RS03215	COG1088	dTDP-glucose 4,6-dehydratase activity
TCARB_RS03220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TCARB_RS03275	COG0438	transferase activity, transferring glycosyl groups
TCARB_RS03285	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TCARB_RS03295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TCARB_RS03335	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_RS03365	COG1373	ATPase (AAA superfamily
TCARB_RS03455	COG0438	transferase activity, transferring glycosyl groups
TCARB_RS03465	COG0489	protein tyrosine kinase activity
TCARB_RS03500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TCARB_RS03550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_RS03565	COG0395	ABC-type sugar transport system, permease component
TCARB_RS03625	COG5012	cobalamin binding
TCARB_RS03645	COG0243	molybdopterin cofactor binding
TCARB_RS03670	COG2267	carboxylic ester hydrolase activity
TCARB_RS03710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TCARB_RS03730	COG1136	(ABC) transporter
TCARB_RS03735	COG0577	efflux transmembrane transporter activity
TCARB_RS03735	COG1136	(ABC) transporter
TCARB_RS03755	COG1131	(ABC) transporter
TCARB_RS03770	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TCARB_RS03830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TCARB_RS03960	COG0438	transferase activity, transferring glycosyl groups
TCARB_RS03965	COG1378	Sugar-specific transcriptional regulator TrmB
TCARB_RS03970	COG1131	(ABC) transporter
TCARB_RS03975	COG0842	Transport permease protein
TCARB_RS03995	COG1063	alcohol dehydrogenase
TCARB_RS04005	COG0531	amino acid
TCARB_RS04015	COG1486	melibiose metabolic process
TCARB_RS04070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCARB_RS04090	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TCARB_RS04115	COG0437	4 iron, 4 sulfur cluster binding
TCARB_RS04120	COG1151	hydroxylamine reductase activity
TCARB_RS04140	COG2111	Na H antiporter
TCARB_RS04140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCARB_RS04145	COG0649	NAD binding
TCARB_RS04145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_RS04150	COG0649	NAD binding
TCARB_RS04160	COG3260	NADH ubiquinone oxidoreductase 20
TCARB_RS04165	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCARB_RS04170	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCARB_RS04200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCARB_RS04210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TCARB_RS04225	COG4555	ABC transporter
TCARB_RS04235	COG4690	dipeptidase activity
TCARB_RS04270	COG2814	Major facilitator Superfamily
TCARB_RS04275	COG0402	S-adenosylhomocysteine deaminase activity
TCARB_RS04280	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_RS04295	COG1122	ATPase activity
TCARB_RS04300	COG1122	ATPase activity
TCARB_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
TCARB_RS04390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCARB_RS04545	COG0471	metal ion transport
TCARB_RS04550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TCARB_RS04620	COG1872	DUF167
TCARB_RS04625	COG4608	Belongs to the ABC transporter superfamily
TCARB_RS04630	COG0444	Belongs to the ABC transporter superfamily
TCARB_RS04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCARB_RS04640	COG0601	transmembrane transport
TCARB_RS04670	COG0698	ribose 5-phosphate isomerase
TCARB_RS04675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCARB_RS04695	COG1435	thymidine kinase activity
TCARB_RS04705	COG3845	ABC transporter
TCARB_RS04710	COG4603	Belongs to the binding-protein-dependent transport system permease family
TCARB_RS04715	COG1079	Belongs to the binding-protein-dependent transport system permease family
TCARB_RS04720	COG1744	ABC transporter substrate-binding protein PnrA-like
TCARB_RS04725	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_RS04750	COG0535	radical SAM domain protein
TCARB_RS04755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TCARB_RS04770	COG1575	Belongs to the MenA family. Type 1 subfamily
TCARB_RS04775	COG0535	radical SAM domain protein
TCARB_RS04785	COG0456	acetyltransferase
TCARB_RS04785	COG1214	PFAM Peptidase M22, glycoprotease
TCARB_RS04790	COG1058	Belongs to the CinA family
TCARB_RS04790	COG1546	Belongs to the CinA family
TCARB_RS04795	COG1309	transcriptional regulator
TCARB_RS04875	COG0450	alkyl hydroperoxide reductase
TCARB_RS04910	COG0419	ATPase involved in DNA repair
TCARB_RS04925	COG0730	response to heat
TCARB_RS04955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TCARB_RS04965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_RS05000	COG0318	PFAM AMP-dependent synthetase and ligase
TCARB_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
TCARB_RS05015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCARB_RS05030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_RS05030	COG1042	CoA-binding domain protein
TCARB_RS05030	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_RS05040	COG3285	dna ligase
TCARB_RS05040	COG1793	dna ligase
TCARB_RS05075	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS05075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCARB_RS05080	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS05090	COG0493	'glutamate synthase
TCARB_RS05130	COG0417	DNA replication proofreading
TCARB_RS05160	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TCARB_RS05160	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TCARB_RS05165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TCARB_RS05175	COG1213	nucleotidyl transferase
TCARB_RS05175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TCARB_RS05280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TCARB_RS05300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TCARB_RS05315	COG0301	tRNA thio-modification
TCARB_RS05315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCARB_RS05330	COG1472	Belongs to the glycosyl hydrolase 3 family
TCARB_RS05350	COG0494	nUDIX hydrolase
TCARB_RS05370	COG4221	oxidoreductase activity
TCARB_RS05415	COG1260	myo-inositol-1-phosphate synthase
TCARB_RS05420	COG4608	Belongs to the ABC transporter superfamily
TCARB_RS05435	COG0601	transmembrane transport
TCARB_RS05440	COG4166	transmembrane transport
TCARB_RS05530	COG4591	ABC-type transport system involved in lipoprotein release permease component
TCARB_RS05535	COG1136	(ABC) transporter
TCARB_RS05555	COG1063	alcohol dehydrogenase
TCARB_RS05560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TCARB_RS05565	COG1840	ABC-type Fe3 transport system, periplasmic component
TCARB_RS05575	COG1177	transmembrane transport
TCARB_RS05580	COG3842	ATPase activity
TCARB_RS05585	COG0584	glycerophosphoryl diester phosphodiesterase
TCARB_RS05590	COG2094	Belongs to the DNA glycosylase MPG family
TCARB_RS05595	COG0470	DNA polymerase III
TCARB_RS05595	COG1067	ATP-dependent peptidase activity
TCARB_RS05610	COG4150	thiosulfate binding
TCARB_RS05615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TCARB_RS05630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TCARB_RS05670	COG0425	Belongs to the sulfur carrier protein TusA family
TCARB_RS05685	COG3842	ATPase activity
TCARB_RS05720	COG0009	L-threonylcarbamoyladenylate synthase
TCARB_RS05735	COG0477	Major facilitator Superfamily
TCARB_RS05745	COG1489	DNA binding
TCARB_RS05760	COG1028	Short-chain dehydrogenase reductase Sdr
TCARB_RS05765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TCARB_RS05775	COG2217	Heavy metal translocating P-type atpase
TCARB_RS05805	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_RS05840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TCARB_RS05845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCARB_RS05860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TCARB_RS05895	COG2033	superoxide reductase activity
TCARB_RS05915	COG0017	Asparaginyl-tRNA synthetase
TCARB_RS05930	COG1528	Iron-storage protein
TCARB_RS05940	COG4948	Mandelate Racemase Muconate Lactonizing
TCARB_RS05950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TCARB_RS05970	COG1363	Peptidase, m42
TCARB_RS05975	COG1592	Rubrerythrin
TCARB_RS05980	COG1522	sequence-specific DNA binding
TCARB_RS06005	COG2814	Major facilitator Superfamily
TCARB_RS06010	COG1122	ATPase activity
TCARB_RS06015	COG1122	ATPase activity
TCARB_RS06020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TCARB_RS06035	COG0563	adenylate kinase activity
TCARB_RS06070	COG3613	nucleoside 2-deoxyribosyltransferase
TCARB_RS06075	COG1522	sequence-specific DNA binding
TCARB_RS06120	COG0436	Aminotransferase
TCARB_RS06195	COG0312	modulator of DNA gyrase
TCARB_RS06200	COG0312	modulator of DNA gyrase
TCARB_RS06250	COG0531	amino acid
TCARB_RS06325	COG0402	S-adenosylhomocysteine deaminase activity
TCARB_RS06330	COG0813	purine-nucleoside phosphorylase activity
TCARB_RS06340	COG0813	purine-nucleoside phosphorylase activity
TCARB_RS06350	COG4720	Psort location CytoplasmicMembrane, score
TCARB_RS06365	COG1122	ATPase activity
TCARB_RS06400	COG2084	Dehydrogenase
TCARB_RS06425	COG0436	Aminotransferase
TCARB_RS06440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCARB_RS06475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TCARB_RS06480	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_RS06535	COG3433	isochorismatase activity
TCARB_RS06535	COG1535	isochorismatase
TCARB_RS06540	COG4974	Belongs to the 'phage' integrase family
TCARB_RS06560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TCARB_RS06570	COG0148	phosphopyruvate hydratase activity
TCARB_RS06575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TCARB_RS06600	COG0084	hydrolase, TatD family'
TCARB_RS06605	COG0439	Biotin carboxylase
TCARB_RS06610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TCARB_RS06615	COG0803	Belongs to the bacterial solute-binding protein 9 family
TCARB_RS06640	COG0813	purine-nucleoside phosphorylase activity
TCARB_RS06660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TCARB_RS06695	COG3276	selenocysteine insertion sequence binding
TCARB_RS06710	COG0717	Belongs to the dCTP deaminase family
TCARB_RS06730	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCARB_RS06740	COG4608	Belongs to the ABC transporter superfamily
TCARB_RS06745	COG0444	Belongs to the ABC transporter superfamily
TCARB_RS06800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TCARB_RS06825	COG0003	Pfam Anion-transporting ATPase
TCARB_RS06840	COG0714	Associated with various cellular activities
TCARB_RS06855	COG0563	adenylate kinase activity
TCARB_RS06880	COG0549	Belongs to the carbamate kinase family
TCARB_RS06895	COG2414	aldehyde ferredoxin oxidoreductase
TCARB_RS06905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TCARB_RS06915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TCARB_RS06915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCARB_RS06925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TCARB_RS06975	COG2379	hydroxypyruvate reductase
TCARB_RS06995	COG0488	(ABC) transporter
TCARB_RS07015	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
TCARB_RS07020	COG0430	RNA-3'-phosphate cyclase activity
TCARB_RS07025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TCARB_RS07035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TCARB_RS07045	COG0081	regulation of translation
TCARB_RS07050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TCARB_RS07055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TCARB_RS07060	COG1252	NADH dehydrogenase
TCARB_RS07065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TCARB_RS07070	COG0089	rRNA binding
TCARB_RS07080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TCARB_RS07110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TCARB_RS07130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TCARB_RS07135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TCARB_RS07145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TCARB_RS07155	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_RS07165	COG0006	proline dipeptidase activity
TCARB_RS07200	COG0436	Aminotransferase
TCARB_RS07210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TCARB_RS07215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TCARB_RS07220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TCARB_RS07235	COG4948	Mandelate Racemase Muconate Lactonizing
TCARB_RS07250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TCARB_RS07250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCARB_RS07255	COG2255	four-way junction helicase activity
TCARB_RS07260	COG0049	tRNA binding
TCARB_RS07280	COG1304	FMN binding
TCARB_RS07285	COG1355	regulation of microtubule-based process
TCARB_RS07290	COG0052	Belongs to the universal ribosomal protein uS2 family
TCARB_RS07310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TCARB_RS07315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TCARB_RS07340	COG1358	cellular component organization or biogenesis
TCARB_RS07350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TCARB_RS07355	COG0085	RNA polymerase activity
TCARB_RS07375	COG0423	glycine-tRNA ligase activity
TCARB_RS07390	COG0864	Transcriptional regulator
TCARB_RS07405	COG0459	protein refolding
TCARB_RS07420	COG1247	-acetyltransferase
TCARB_RS07440	COG0417	DNA replication proofreading
TCARB_RS07480	COG1598	PFAM Uncharacterised protein family UPF0150
TCARB_RS07530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TCARB_RS07535	COG1047	Peptidyl-prolyl cis-trans
TCARB_RS07550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TCARB_RS07555	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_RS07570	COG0521	Mo-molybdopterin cofactor biosynthetic process
TCARB_RS07575	COG0315	cyclic pyranopterin monophosphate synthase activity
TCARB_RS07590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCARB_RS07595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCARB_RS07605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TCARB_RS07610	COG2234	aminopeptidase activity
TCARB_RS07630	COG0525	valine-tRNA ligase activity
TCARB_RS07640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TCARB_RS07655	COG0469	pyruvate kinase activity
TCARB_RS07685	COG1328	CTP reductase activity
TCARB_RS07690	COG1042	CoA-binding domain protein
TCARB_RS07690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_RS07690	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_RS07695	COG1269	ATP hydrolysis coupled proton transport
TCARB_RS07720	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TCARB_RS07740	COG0501	Belongs to the peptidase M48B family
TCARB_RS07800	COG0343	queuine tRNA-ribosyltransferase activity
TCARB_RS07820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TCARB_RS07865	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TCARB_RS07880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TCARB_RS07905	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TCARB_RS07930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TCARB_RS07935	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_RS07940	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCARB_RS07945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCARB_RS07970	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TCARB_RS08050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TCARB_RS08065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TCARB_RS08070	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TCARB_RS08085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TCARB_RS08135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TCARB_RS08140	COG1793	dna ligase
TCARB_RS08150	COG3276	selenocysteine insertion sequence binding
TCARB_RS08155	COG0457	Tetratricopeptide repeat
TCARB_RS08155	COG0552	protein localization to endoplasmic reticulum
TCARB_RS08210	COG1144	Oxidoreductase
TCARB_RS08215	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS08220	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS08225	COG1110	DNA topoisomerase II activity
TCARB_RS08230	COG1051	belongs to the nudix hydrolase family
TCARB_RS08230	COG1056	cytidyltransferase-related domain
TCARB_RS08240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TCARB_RS08260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TCARB_RS08345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_RS08365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TCARB_RS08375	COG1522	sequence-specific DNA binding
TCARB_RS08385	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TCARB_RS08390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TCARB_RS08410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TCARB_RS08460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TCARB_RS08475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_RS08480	COG1078	dGTPase activity
TCARB_RS08485	COG0071	Belongs to the small heat shock protein (HSP20) family
TCARB_RS08490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_RS08505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TCARB_RS08540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TCARB_RS08550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TCARB_RS08565	COG2264	protein methyltransferase activity
TCARB_RS08580	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TCARB_RS08605	COG1192	Involved in chromosome partitioning
TCARB_RS08635	COG2226	methyltransferase
TCARB_RS08645	COG0010	Belongs to the arginase family
TCARB_RS08665	COG1773	rubredoxin
TCARB_RS08665	COG0426	domain, Protein
TCARB_RS08670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TCARB_RS08690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TCARB_RS08715	COG1358	cellular component organization or biogenesis
TCARB_RS08720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TCARB_RS08720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCARB_RS08735	COG1185	polyribonucleotide nucleotidyltransferase activity
TCARB_RS08745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TCARB_RS08780	COG0419	ATPase involved in DNA repair
TCARB_RS08870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TCARB_RS08985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TCARB_RS08995	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS09000	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCARB_RS09010	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TCARB_RS09060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TCARB_RS09135	COG0495	leucyl-tRNA aminoacylation
TCARB_RS09145	COG0180	Tryptophanyl-tRNA synthetase
TCARB_RS09150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TCARB_RS09150	COG0574	Belongs to the PEP-utilizing enzyme family
TCARB_RS09155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
TCARB_RS09170	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
TCARB_RS09185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCARB_RS09195	COG0410	ABC transporter
TCARB_RS09210	COG0045	succinate-CoA ligase (ADP-forming) activity
TCARB_RS09210	COG1042	CoA-binding domain protein
TCARB_RS09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TCARB_RS09215	COG0432	Pfam Uncharacterised protein family UPF0047
TCARB_RS09220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TCARB_RS09235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TCARB_RS09250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TCARB_RS09260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TCARB_RS09270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCARB_RS09275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCARB_RS09280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TCARB_RS09285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TCARB_RS09300	COG1793	dna ligase
TCARB_RS09300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCARB_RS09330	COG0017	Asparaginyl-tRNA synthetase
TCARB_RS09350	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TCARB_RS09385	COG1185	polyribonucleotide nucleotidyltransferase activity
TCARB_RS09395	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TCARB_RS09400	COG0051	transcription antitermination factor activity, RNA binding
TCARB_RS09425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TCARB_RS09455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCARB_RS09460	COG0124	histidyl-tRNA synthetase
TCARB_RS09465	COG2222	sugar isomerase
TCARB_RS09495	COG1234	tRNA 3'-trailer cleavage
TCARB_RS09530	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TCARB_RS09530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TCARB_RS09535	COG1515	deoxyribonuclease V activity
TCARB_RS09545	COG0024	Methionine aminopeptidase