locus-tag	class	description
IG193_RS00015	COG0383	alpha-mannosidase activity
IG193_RS00025	COG0805	protein transport
IG193_RS00105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IG193_RS00140	COG5012	cobalamin binding
IG193_RS00150	COG0393	Putative heavy-metal-binding
IG193_RS00180	COG0437	4 iron, 4 sulfur cluster binding
IG193_RS00205	COG0517	IMP dehydrogenase activity
IG193_RS00205	COG0516	GMP reductase activity
IG193_RS00210	COG0531	amino acid
IG193_RS00215	COG2267	carboxylic ester hydrolase activity
IG193_RS00230	COG0477	Major facilitator Superfamily
IG193_RS00255	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IG193_RS00260	COG0747	negative chemotaxis
IG193_RS00265	COG0601	transmembrane transport
IG193_RS00275	COG0444	Belongs to the ABC transporter superfamily
IG193_RS00280	COG4608	Belongs to the ABC transporter superfamily
IG193_RS00295	COG1408	metallophosphoesterase
IG193_RS00305	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IG193_RS00310	COG3273	potassium ion transport
IG193_RS00310	COG0471	metal ion transport
IG193_RS00335	COG0586	Pfam SNARE associated Golgi protein
IG193_RS00365	COG0515	serine threonine protein kinase
IG193_RS00365	COG2815	serine threonine protein kinase
IG193_RS00405	COG1404	Belongs to the peptidase S8 family
IG193_RS00480	COG0515	serine threonine protein kinase
IG193_RS00480	COG2815	serine threonine protein kinase
IG193_RS00510	COG0515	serine threonine protein kinase
IG193_RS00585	COG1063	alcohol dehydrogenase
IG193_RS00640	COG1201	RNA secondary structure unwinding
IG193_RS00805	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IG193_RS00850	COG1506	peptidase
IG193_RS00850	COG0823	Involved in the tonB-independent uptake of proteins
IG193_RS00865	COG1268	BioY protein
IG193_RS00890	COG2211	Major facilitator Superfamily
IG193_RS00900	COG1271	oxidase subunit
IG193_RS00920	COG1505	serine-type exopeptidase activity
IG193_RS00935	COG1346	cytolysis
IG193_RS00940	COG1380	Effector of murein hydrolase LrgA
IG193_RS00975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IG193_RS00980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IG193_RS01005	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IG193_RS01035	COG0535	radical SAM domain protein
IG193_RS01040	COG0864	Transcriptional regulator
IG193_RS01075	COG4133	protoheme IX ABC transporter activity
IG193_RS01145	COG0494	nUDIX hydrolase
IG193_RS01175	COG0493	'glutamate synthase
IG193_RS01180	COG3585	molybdate ion transport
IG193_RS01180	COG2005	Transcriptional regulator
IG193_RS01240	COG1850	ribulose-bisphosphate carboxylase activity
IG193_RS01250	COG0395	ABC-type sugar transport system, permease component
IG193_RS01255	COG1175	transmembrane transport
IG193_RS01280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IG193_RS01285	COG1486	melibiose metabolic process
IG193_RS01320	COG0556	nucleotide-excision repair
IG193_RS01325	COG5297	Belongs to the glycosyl hydrolase family 6
IG193_RS01325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IG193_RS01365	COG0644	oxidoreductase
IG193_RS01375	COG0037	tRNA processing
IG193_RS01415	COG3842	ATPase activity
IG193_RS01420	COG3833	ABC-type maltose transport systems, permease component
IG193_RS01440	COG1131	(ABC) transporter
IG193_RS01460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IG193_RS01475	COG1305	Transglutaminase-like
IG193_RS01490	COG0543	2 iron, 2 sulfur cluster binding
IG193_RS01495	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IG193_RS01500	COG0540	Belongs to the ATCase OTCase family
IG193_RS01510	COG0284	orotidine-5'-phosphate decarboxylase activity
IG193_RS01515	COG1051	belongs to the nudix hydrolase family
IG193_RS01540	COG0438	transferase activity, transferring glycosyl groups
IG193_RS01550	COG0395	ABC-type sugar transport system, permease component
IG193_RS01555	COG1175	transmembrane transport
IG193_RS01560	COG1653	transport
IG193_RS01575	COG1070	Carbohydrate kinase
IG193_RS01580	COG0395	ABC-type sugar transport system, permease component
IG193_RS01585	COG1175	transmembrane transport
IG193_RS01595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IG193_RS01610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IG193_RS01615	COG3836	Belongs to the HpcH HpaI aldolase family
IG193_RS01645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IG193_RS01650	COG0167	dihydroorotate dehydrogenase activity
IG193_RS01660	COG0504	CTP synthase activity
IG193_RS01670	COG3842	ATPase activity
IG193_RS01720	COG2431	L-lysine efflux transmembrane transporter activity
IG193_RS01725	COG4221	oxidoreductase activity
IG193_RS01755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IG193_RS01760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IG193_RS01770	COG2009	succinate dehydrogenase
IG193_RS01800	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IG193_RS01805	COG1085	galactose-1-phosphate uridylyltransferase
IG193_RS01835	COG1122	ATPase activity
IG193_RS01850	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IG193_RS01855	COG0561	phosphatase activity
IG193_RS01860	COG3716	PTS system mannose fructose sorbose family IID component
IG193_RS01870	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IG193_RS01880	COG0673	inositol 2-dehydrogenase activity
IG193_RS01890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IG193_RS01905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IG193_RS01960	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IG193_RS02050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IG193_RS02055	COG1216	Glycosyl transferase, family 2
IG193_RS02060	COG0438	transferase activity, transferring glycosyl groups
IG193_RS02085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IG193_RS02090	COG0438	transferase activity, transferring glycosyl groups
IG193_RS02110	COG1215	transferase activity, transferring glycosyl groups
IG193_RS02165	COG0714	Associated with various cellular activities
IG193_RS02210	COG0463	Glycosyl transferase, family 2
IG193_RS02225	COG0297	glycogen (starch) synthase activity
IG193_RS02225	COG0438	transferase activity, transferring glycosyl groups
IG193_RS02280	COG4821	SIS domain
IG193_RS02285	COG0174	glutamine synthetase
IG193_RS02290	COG1007	ATP synthesis coupled electron transport
IG193_RS02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IG193_RS02300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IG193_RS02305	COG0713	ATP synthesis coupled electron transport
IG193_RS02320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IG193_RS02325	COG0649	NAD binding
IG193_RS02330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IG193_RS02335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IG193_RS02345	COG0651	ATP synthesis coupled electron transport
IG193_RS02350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IG193_RS02355	COG0713	ATP synthesis coupled electron transport
IG193_RS02365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IG193_RS02375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IG193_RS02375	COG0649	NAD binding
IG193_RS02380	COG3260	NADH ubiquinone oxidoreductase 20
IG193_RS02385	COG0704	Plays a role in the regulation of phosphate uptake
IG193_RS02400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IG193_RS02410	COG0517	IMP dehydrogenase activity
IG193_RS02410	COG0516	GMP reductase activity
IG193_RS02420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IG193_RS02420	COG0519	Catalyzes the synthesis of GMP from XMP
IG193_RS02425	COG1342	Belongs to the UPF0251 family
IG193_RS02430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IG193_RS02445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IG193_RS02465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IG193_RS02470	COG0573	inorganic phosphate transmembrane transporter activity
IG193_RS02475	COG0581	inorganic phosphate transmembrane transporter activity
IG193_RS02480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IG193_RS02485	COG0303	'Molybdopterin
IG193_RS02495	COG1254	Belongs to the acylphosphatase family
IG193_RS02520	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
IG193_RS02545	COG0109	protoheme IX farnesyltransferase activity
IG193_RS02555	COG0310	cobalt ion transport
IG193_RS02570	COG1122	ATPase activity
IG193_RS02620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IG193_RS02645	COG0673	inositol 2-dehydrogenase activity
IG193_RS02650	COG1201	RNA secondary structure unwinding
IG193_RS02705	COG0402	S-adenosylhomocysteine deaminase activity
IG193_RS02735	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IG193_RS02770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IG193_RS02790	COG0656	L-ascorbic acid biosynthetic process
IG193_RS02800	COG1122	ATPase activity
IG193_RS02805	COG1122	ATPase activity
IG193_RS02865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IG193_RS02910	COG1201	RNA secondary structure unwinding
IG193_RS02920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IG193_RS02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IG193_RS02930	COG0706	membrane insertase activity
IG193_RS02940	COG1201	RNA secondary structure unwinding
IG193_RS02945	COG2813	Specifically methylates the guanine in position
IG193_RS02950	COG0017	Asparaginyl-tRNA synthetase
IG193_RS02960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IG193_RS02980	COG0501	Belongs to the peptidase M48B family
IG193_RS02985	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IG193_RS03000	COG1013	pyruvate-flavodoxin oxidoreductase activity
IG193_RS03005	COG0674	pyruvate-flavodoxin oxidoreductase activity
IG193_RS03005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IG193_RS03055	COG1940	carbohydrate kinase activity
IG193_RS03060	COG0215	cysteine-tRNA ligase activity
IG193_RS03070	COG1126	abc transporter atp-binding protein
IG193_RS03075	COG0765	amino acid transport
IG193_RS03090	COG0489	protein tyrosine kinase activity
IG193_RS03110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IG193_RS03140	COG0037	tRNA processing
IG193_RS03200	COG2151	metal-sulfur cluster biosynthetic enzyme
IG193_RS03205	COG0632	four-way junction helicase activity
IG193_RS03230	COG0085	RNA polymerase activity
IG193_RS03235	COG0149	triose-phosphate isomerase activity
IG193_RS03245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IG193_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IG193_RS03260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IG193_RS03265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IG193_RS03270	COG1402	creatininase
IG193_RS03275	COG1063	alcohol dehydrogenase
IG193_RS03280	COG1082	Xylose isomerase domain protein TIM barrel
IG193_RS03290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IG193_RS03295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IG193_RS03310	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IG193_RS03365	COG0330	HflC and HflK could
IG193_RS03410	COG1446	asparaginase
IG193_RS03415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IG193_RS03430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IG193_RS03495	COG2835	tetraacyldisaccharide 4'-kinase activity
IG193_RS03500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IG193_RS03520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IG193_RS03545	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IG193_RS03580	COG1573	uracil-dna glycosylase
IG193_RS03625	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IG193_RS03635	COG0297	glycogen (starch) synthase activity
IG193_RS03640	COG1449	Belongs to the glycosyl hydrolase 57 family
IG193_RS03675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IG193_RS03680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IG193_RS03690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IG193_RS03705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IG193_RS03705	COG0301	tRNA thio-modification
IG193_RS03710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IG193_RS03710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IG193_RS03735	COG0126	phosphoglycerate kinase activity
IG193_RS03770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IG193_RS03780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IG193_RS03790	COG1793	dna ligase
IG193_RS03800	COG2078	PFAM AMMECR1 domain protein
IG193_RS03910	COG0051	transcription antitermination factor activity, RNA binding
IG193_RS03915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IG193_RS03920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IG193_RS03930	COG0017	Asparaginyl-tRNA synthetase
IG193_RS03940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IG193_RS03940	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IG193_RS03975	COG1234	tRNA 3'-trailer cleavage
IG193_RS04010	COG2222	sugar isomerase
IG193_RS04015	COG0124	histidyl-tRNA synthetase
IG193_RS04020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IG193_RS04050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IG193_RS04075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IG193_RS04090	COG1515	deoxyribonuclease V activity
IG193_RS04100	COG0024	Methionine aminopeptidase
IG193_RS04110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IG193_RS04150	COG1733	regulation of RNA biosynthetic process
IG193_RS04165	COG0673	inositol 2-dehydrogenase activity
IG193_RS04175	COG2226	methyltransferase
IG193_RS04210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IG193_RS04240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IG193_RS04270	COG5002	protein histidine kinase activity
IG193_RS04365	COG0585	pseudouridine synthase activity
IG193_RS04370	COG1444	tRNA N-acetyltransferase activity
IG193_RS04380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IG193_RS04405	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
IG193_RS04425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IG193_RS04430	COG1122	ATPase activity
IG193_RS04435	COG1122	ATPase activity
IG193_RS04440	COG0012	GTP binding
IG193_RS04450	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IG193_RS04460	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IG193_RS04465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IG193_RS04470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IG193_RS04480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IG193_RS04490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IG193_RS04505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IG193_RS04515	COG0142	geranyltranstransferase activity
IG193_RS04525	COG0432	Pfam Uncharacterised protein family UPF0047
IG193_RS04545	COG3842	ATPase activity
IG193_RS04560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IG193_RS04575	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
IG193_RS04595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IG193_RS04595	COG0574	Belongs to the PEP-utilizing enzyme family
IG193_RS04630	COG1618	nucleotide phosphatase activity, acting on free nucleotides
IG193_RS04635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IG193_RS04640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IG193_RS04660	COG1522	sequence-specific DNA binding
IG193_RS04665	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IG193_RS04745	COG1196	nuclear chromosome segregation
IG193_RS04805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IG193_RS04820	COG0674	pyruvate-flavodoxin oxidoreductase activity
IG193_RS04825	COG1013	pyruvate-flavodoxin oxidoreductase activity
IG193_RS04835	COG0023	Translation Initiation Factor
IG193_RS04840	COG0071	Belongs to the small heat shock protein (HSP20) family
IG193_RS04850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IG193_RS04905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IG193_RS04945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IG193_RS04980	COG1051	belongs to the nudix hydrolase family
IG193_RS04980	COG1056	cytidyltransferase-related domain
IG193_RS04985	COG1110	DNA topoisomerase II activity
IG193_RS04990	COG1013	pyruvate-flavodoxin oxidoreductase activity
IG193_RS04995	COG0674	pyruvate-flavodoxin oxidoreductase activity
IG193_RS05000	COG1144	Oxidoreductase
IG193_RS05005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IG193_RS05030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IG193_RS05035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IG193_RS05035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IG193_RS05060	COG4581	dead DEAH box helicase
IG193_RS05065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IG193_RS05095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IG193_RS05100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IG193_RS05115	COG2264	protein methyltransferase activity
IG193_RS05125	COG0528	UMP kinase activity
IG193_RS05145	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IG193_RS05150	COG0071	Belongs to the small heat shock protein (HSP20) family
IG193_RS05165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IG193_RS05200	COG0495	leucyl-tRNA aminoacylation
IG193_RS05220	COG0010	Belongs to the arginase family
IG193_RS05230	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IG193_RS05280	COG0116	Belongs to the methyltransferase superfamily
IG193_RS05280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IG193_RS05330	COG1773	rubredoxin
IG193_RS05330	COG0426	domain, Protein
IG193_RS05360	COG0180	Tryptophanyl-tRNA synthetase
IG193_RS05370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IG193_RS05375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IG193_RS05390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IG193_RS05395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IG193_RS05410	COG1078	dGTPase activity
IG193_RS05420	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IG193_RS05455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IG193_RS05455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IG193_RS05460	COG1793	dna ligase
IG193_RS05495	COG0552	protein localization to endoplasmic reticulum
IG193_RS05500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IG193_RS05520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IG193_RS05600	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
IG193_RS05625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IG193_RS05630	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IG193_RS05635	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IG193_RS05640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IG193_RS05655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IG193_RS05660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IG193_RS05700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IG193_RS05710	COG4991	sh3 domain protein
IG193_RS05710	COG3064	Membrane
IG193_RS05710	COG0515	serine threonine protein kinase
IG193_RS05720	COG2226	methyltransferase
IG193_RS05745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IG193_RS05765	COG0343	queuine tRNA-ribosyltransferase activity
IG193_RS05795	COG0501	Belongs to the peptidase M48B family
IG193_RS05845	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
IG193_RS05865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IG193_RS05870	COG2234	aminopeptidase activity
IG193_RS05910	COG1269	ATP hydrolysis coupled proton transport
IG193_RS05930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IG193_RS05940	COG0525	valine-tRNA ligase activity
IG193_RS05975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IG193_RS05990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IG193_RS06000	COG0315	cyclic pyranopterin monophosphate synthase activity
IG193_RS06020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IG193_RS06025	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
IG193_RS06040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IG193_RS06085	COG0417	DNA replication proofreading
IG193_RS06125	COG0459	protein refolding
IG193_RS06155	COG0423	glycine-tRNA ligase activity
IG193_RS06165	COG0085	RNA polymerase activity
IG193_RS06170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IG193_RS06175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IG193_RS06200	COG0200	Binds to the 23S rRNA
IG193_RS06205	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IG193_RS06210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IG193_RS06240	COG0052	Belongs to the universal ribosomal protein uS2 family
IG193_RS06245	COG1355	regulation of microtubule-based process
IG193_RS06250	COG1304	FMN binding
IG193_RS06270	COG0049	tRNA binding
IG193_RS06275	COG2255	four-way junction helicase activity
IG193_RS06290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IG193_RS06335	COG0436	Aminotransferase
IG193_RS06345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IG193_RS06350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IG193_RS06355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IG193_RS06370	COG4948	Mandelate Racemase Muconate Lactonizing
IG193_RS06385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IG193_RS06395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IG193_RS06405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IG193_RS06425	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IG193_RS06435	COG0200	Binds to the 23S rRNA
IG193_RS06455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IG193_RS06465	COG0089	rRNA binding
IG193_RS06470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IG193_RS06475	COG1252	NADH dehydrogenase
IG193_RS06480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IG193_RS06485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IG193_RS06490	COG0081	regulation of translation
IG193_RS06495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IG193_RS06515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IG193_RS06520	COG0430	RNA-3'-phosphate cyclase activity
IG193_RS06545	COG0488	(ABC) transporter
IG193_RS06560	COG2379	hydroxypyruvate reductase
IG193_RS06625	COG0714	Associated with various cellular activities
IG193_RS06665	COG0549	Belongs to the carbamate kinase family
IG193_RS06680	COG2414	aldehyde ferredoxin oxidoreductase
IG193_RS06690	COG0746	molybdenum cofactor guanylyltransferase activity
IG193_RS06700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IG193_RS06700	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IG193_RS06710	COG1980	fructose-bisphosphate aldolase activity
IG193_RS06720	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IG193_RS06725	COG0003	Pfam Anion-transporting ATPase
IG193_RS06735	COG1522	sequence-specific DNA binding
IG193_RS06745	COG0037	tRNA processing
IG193_RS06765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IG193_RS06775	COG1216	Glycosyl transferase, family 2
IG193_RS06795	COG0747	negative chemotaxis
IG193_RS06800	COG0601	transmembrane transport
IG193_RS06810	COG0444	Belongs to the ABC transporter superfamily
IG193_RS06815	COG4608	Belongs to the ABC transporter superfamily
IG193_RS06830	COG0785	Cytochrome C biogenesis protein
IG193_RS06845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IG193_RS06865	COG0717	Belongs to the dCTP deaminase family
IG193_RS06870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IG193_RS06875	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IG193_RS06890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IG193_RS06895	COG0805	protein transport
IG193_RS06910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IG193_RS06915	COG0813	purine-nucleoside phosphorylase activity
IG193_RS06935	COG1121	(ABC) transporter
IG193_RS06950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IG193_RS06955	COG0439	Biotin carboxylase
IG193_RS06960	COG0084	hydrolase, TatD family'
IG193_RS06985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IG193_RS07000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IG193_RS07025	COG4974	Belongs to the 'phage' integrase family
IG193_RS07040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IG193_RS07040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IG193_RS07080	COG2414	aldehyde ferredoxin oxidoreductase
IG193_RS07085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IG193_RS07140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IG193_RS07160	COG0436	Aminotransferase
IG193_RS07210	COG1032	radical SAM domain protein
IG193_RS07225	COG4721	ABC-type cobalt transport system, permease component
IG193_RS07230	COG1122	ATPase activity
IG193_RS07265	COG0813	purine-nucleoside phosphorylase activity
IG193_RS07270	COG0402	S-adenosylhomocysteine deaminase activity
IG193_RS07325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IG193_RS07335	COG0667	Aldo Keto reductase
IG193_RS07360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IG193_RS07380	COG0312	modulator of DNA gyrase
IG193_RS07385	COG0312	modulator of DNA gyrase
IG193_RS07460	COG0436	Aminotransferase
IG193_RS07495	COG1522	sequence-specific DNA binding
IG193_RS07500	COG3613	nucleoside 2-deoxyribosyltransferase
IG193_RS07535	COG0563	adenylate kinase activity
IG193_RS07565	COG1363	Peptidase, m42
IG193_RS07575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IG193_RS07610	COG4948	Mandelate Racemase Muconate Lactonizing
IG193_RS07640	COG2033	superoxide reductase activity
IG193_RS07645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IG193_RS07665	COG0616	signal peptide processing
IG193_RS07700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IG193_RS07725	COG1489	DNA binding
IG193_RS07760	COG0009	L-threonylcarbamoyladenylate synthase
IG193_RS07805	COG0631	protein serine/threonine phosphatase activity
IG193_RS07815	COG2815	serine threonine protein kinase
IG193_RS07815	COG0515	serine threonine protein kinase
IG193_RS07845	COG2304	oxidoreductase activity
IG193_RS07850	COG0450	alkyl hydroperoxide reductase
IG193_RS07870	COG0419	ATPase involved in DNA repair
IG193_RS07875	COG0698	ribose 5-phosphate isomerase
IG193_RS07910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IG193_RS07950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IG193_RS07980	COG5012	cobalamin binding
IG193_RS07990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IG193_RS08010	COG0778	Nitroreductase
IG193_RS08015	COG2094	Belongs to the DNA glycosylase MPG family
IG193_RS08030	COG1136	(ABC) transporter
IG193_RS08040	COG1122	ATPase activity
IG193_RS08070	COG1372	Participates in initiation and elongation during chromosome replication
IG193_RS08070	COG0719	Fe-S assembly protein
IG193_RS08085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IG193_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
IG193_RS08120	COG2414	aldehyde ferredoxin oxidoreductase
IG193_RS08125	COG0437	4 iron, 4 sulfur cluster binding
IG193_RS08140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IG193_RS08145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IG193_RS08150	COG0017	Asparaginyl-tRNA synthetase
IG193_RS08165	COG0351	phosphomethylpyrimidine kinase
IG193_RS08165	COG0352	thiamine-phosphate diphosphorylase activity
IG193_RS08270	COG2427	Protein of unknown function (DUF1641)
IG193_RS08280	COG0425	Belongs to the sulfur carrier protein TusA family
IG193_RS08290	COG0109	protoheme IX farnesyltransferase activity
IG193_RS08305	COG3842	ATPase activity
IG193_RS08310	COG4149	molybdate abc transporter
IG193_RS08350	COG1131	(ABC) transporter
IG193_RS08360	COG0577	efflux transmembrane transporter activity
IG193_RS08360	COG1136	(ABC) transporter
IG193_RS08365	COG1136	(ABC) transporter
IG193_RS08375	COG0409	Hydrogenase expression formation protein
IG193_RS08380	COG3383	formate dehydrogenase (NAD+) activity
IG193_RS08395	COG0778	Nitroreductase
IG193_RS08405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IG193_RS08410	COG1830	Aldolase
IG193_RS08415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IG193_RS08415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IG193_RS08420	COG0534	Mate efflux family protein
IG193_RS08425	COG0709	Synthesizes selenophosphate from selenide and ATP
IG193_RS08450	COG0121	glutamine amidotransferase
IG193_RS08465	COG0371	Dehydrogenase
IG193_RS08480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IG193_RS08515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IG193_RS08520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IG193_RS08525	COG0531	amino acid
IG193_RS08535	COG0471	metal ion transport
IG193_RS08800	COG1254	Belongs to the acylphosphatase family
IG193_RS08855	COG0601	transmembrane transport
IG193_RS08860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IG193_RS08870	COG4608	Belongs to the ABC transporter superfamily
IG193_RS08905	COG1131	(ABC) transporter
IG193_RS08930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IG193_RS08945	COG1175	transmembrane transport
IG193_RS08980	COG1418	mRNA catabolic process
IG193_RS08990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IG193_RS09035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IG193_RS09050	COG2095	MarC family integral membrane protein
IG193_RS09105	COG0719	Fe-S assembly protein