locus-tag	class	description
HPC62_RS00105	COG0387	Pfam Sodium calcium exchanger
HPC62_RS00125	COG2204	response regulator
HPC62_RS00175	COG1132	(ABC) transporter
HPC62_RS00250	COG4372	Transposase
HPC62_RS00255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS00260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HPC62_RS00310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HPC62_RS00315	COG0848	biopolymer transport protein
HPC62_RS00320	COG0811	peptide transport
HPC62_RS00340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPC62_RS00365	COG3655	Transcriptional regulator
HPC62_RS00390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HPC62_RS00410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPC62_RS00410	COG0574	Belongs to the PEP-utilizing enzyme family
HPC62_RS00415	COG0440	acetolactate synthase activity
HPC62_RS00425	COG0148	phosphopyruvate hydratase activity
HPC62_RS00445	COG2912	Transglutaminase-like superfamily
HPC62_RS00455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPC62_RS00460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HPC62_RS00470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPC62_RS00485	COG0724	RNA recognition motif
HPC62_RS00490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPC62_RS00500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPC62_RS00505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPC62_RS00510	COG0750	zinc metalloprotease
HPC62_RS00515	COG0509	glycine decarboxylation via glycine cleavage system
HPC62_RS00520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HPC62_RS00525	COG0346	lactoylglutathione lyase activity
HPC62_RS00535	COG0166	Belongs to the GPI family
HPC62_RS00555	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS00580	COG0004	ammonium transporteR
HPC62_RS00585	COG1104	cysteine desulfurase activity
HPC62_RS00590	COG4249	Peptidase C14 caspase catalytic subunit p20
HPC62_RS00590	COG2319	Wd-40 repeat
HPC62_RS00600	COG0515	serine threonine protein kinase
HPC62_RS00620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPC62_RS00625	COG0537	adenosine 5'-monophosphoramidase activity
HPC62_RS00655	COG1280	lysine exporter protein (LysE YggA)
HPC62_RS00685	COG0745	RESPONSE REGULATOR receiver
HPC62_RS00705	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HPC62_RS00715	COG0784	Response regulator, receiver
HPC62_RS00715	COG2205	protein histidine kinase activity
HPC62_RS00715	COG5002	protein histidine kinase activity
HPC62_RS00780	COG0135	phosphoribosylanthranilate isomerase activity
HPC62_RS00790	COG1994	Peptidase M50
HPC62_RS00790	COG0517	IMP dehydrogenase activity
HPC62_RS00800	COG0788	formyltetrahydrofolate deformylase activity
HPC62_RS00805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HPC62_RS00815	COG0557	exoribonuclease II activity
HPC62_RS00820	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPC62_RS00825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HPC62_RS00830	COG0303	'Molybdopterin
HPC62_RS00835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPC62_RS00845	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPC62_RS00860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPC62_RS00875	COG2723	6-phospho-beta-galactosidase activity
HPC62_RS00880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPC62_RS00890	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HPC62_RS00895	COG2094	Belongs to the DNA glycosylase MPG family
HPC62_RS00940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPC62_RS01005	COG1032	radical SAM domain protein
HPC62_RS01050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HPC62_RS01070	COG2183	response to ionizing radiation
HPC62_RS01080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPC62_RS01090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPC62_RS01115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HPC62_RS01120	COG0189	ligase activity
HPC62_RS01135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HPC62_RS01145	COG0402	S-adenosylhomocysteine deaminase activity
HPC62_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
HPC62_RS01165	COG0583	DNA-binding transcription factor activity
HPC62_RS01170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPC62_RS01180	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HPC62_RS01200	COG0822	iron-sulfur transferase activity
HPC62_RS01205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HPC62_RS01230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS01235	COG1528	Iron-storage protein
HPC62_RS01245	COG0318	PFAM AMP-dependent synthetase and ligase
HPC62_RS01265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS01275	COG0330	HflC and HflK could
HPC62_RS01305	COG2066	Belongs to the glutaminase family
HPC62_RS01310	COG0489	protein tyrosine kinase activity
HPC62_RS01325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPC62_RS01340	COG0045	succinate-CoA ligase (ADP-forming) activity
HPC62_RS01360	COG0151	Belongs to the GarS family
HPC62_RS01375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPC62_RS01405	COG0402	S-adenosylhomocysteine deaminase activity
HPC62_RS01415	COG0228	four-way junction DNA binding
HPC62_RS01425	COG1702	phosphate starvation-inducible protein PhoH
HPC62_RS01440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HPC62_RS01445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HPC62_RS01450	COG4956	integral membrane protein (PIN domain superfamily)
HPC62_RS01455	COG2226	methyltransferase
HPC62_RS01460	COG0431	NADPH-dependent FMN reductase
HPC62_RS01465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPC62_RS01475	COG0583	DNA-binding transcription factor activity
HPC62_RS01480	COG0515	serine threonine protein kinase
HPC62_RS01490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HPC62_RS01500	COG0659	secondary active sulfate transmembrane transporter activity
HPC62_RS01505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HPC62_RS01520	COG0534	Mate efflux family protein
HPC62_RS01545	COG0511	ligase activity, forming carbon-carbon bonds
HPC62_RS01550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPC62_RS01555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HPC62_RS01565	COG0159	tryptophan synthase activity
HPC62_RS01575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS01585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HPC62_RS01595	COG0741	lytic transglycosylase activity
HPC62_RS01595	COG0739	heme binding
HPC62_RS01595	COG1196	nuclear chromosome segregation
HPC62_RS01600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HPC62_RS01605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HPC62_RS01615	COG4106	trans-aconitate 2-methyltransferase activity
HPC62_RS01625	COG0156	8-amino-7-oxononanoate synthase activity
HPC62_RS01635	COG0745	RESPONSE REGULATOR receiver
HPC62_RS01645	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HPC62_RS01660	COG2367	Beta-lactamase
HPC62_RS01665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HPC62_RS01670	COG0739	heme binding
HPC62_RS01705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPC62_RS01715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPC62_RS01715	COG0140	phosphoribosyl-ATP diphosphatase activity
HPC62_RS01750	COG1132	(ABC) transporter
HPC62_RS01775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPC62_RS01785	COG4251	negative regulation of phosphorylation
HPC62_RS01785	COG3706	GGDEF domain
HPC62_RS01785	COG2203	Gaf domain
HPC62_RS01785	COG5001	Diguanylate cyclase
HPC62_RS01790	COG2205	protein histidine kinase activity
HPC62_RS01790	COG0784	Response regulator, receiver
HPC62_RS01795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HPC62_RS01800	COG5001	Diguanylate cyclase
HPC62_RS01800	COG3300	MHYT domain
HPC62_RS01810	COG0003	Pfam Anion-transporting ATPase
HPC62_RS01815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HPC62_RS01820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPC62_RS01825	COG2226	methyltransferase
HPC62_RS01850	COG0592	DNA-directed DNA polymerase activity
HPC62_RS01860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HPC62_RS01865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HPC62_RS01880	COG0583	DNA-binding transcription factor activity
HPC62_RS01895	COG0515	serine threonine protein kinase
HPC62_RS01920	COG0339	signal peptide processing
HPC62_RS01940	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS01945	COG0463	Glycosyl transferase, family 2
HPC62_RS01955	COG0489	protein tyrosine kinase activity
HPC62_RS01995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HPC62_RS02005	COG4242	Belongs to the peptidase S51 family
HPC62_RS02040	COG2124	cytochrome p450
HPC62_RS02070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HPC62_RS02100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPC62_RS02135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPC62_RS02135	COG0189	ligase activity
HPC62_RS02145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPC62_RS02185	COG2048	Heterodisulfide reductase, subunit B
HPC62_RS02200	COG1473	amidohydrolase
HPC62_RS02205	COG1116	anion transmembrane transporter activity
HPC62_RS02230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPC62_RS02235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPC62_RS02255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS02260	COG0811	peptide transport
HPC62_RS02270	COG0848	biopolymer transport protein
HPC62_RS02285	COG0384	phenazine biosynthesis protein PhzF
HPC62_RS02290	COG0586	Pfam SNARE associated Golgi protein
HPC62_RS02295	COG1073	alpha beta
HPC62_RS02310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPC62_RS02315	COG0667	Aldo Keto reductase
HPC62_RS02320	COG2884	Cell division ATP-binding protein ftsE
HPC62_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS02375	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPC62_RS02385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HPC62_RS02420	COG2885	chlorophyll binding
HPC62_RS02425	COG2885	chlorophyll binding
HPC62_RS02430	COG2133	pyrroloquinoline quinone binding
HPC62_RS02440	COG0174	glutamine synthetase
HPC62_RS02445	COG5002	protein histidine kinase activity
HPC62_RS02460	COG4636	protein conserved in cyanobacteria
HPC62_RS02465	COG0300	oxidoreductase activity
HPC62_RS02475	COG1074	ATP-dependent DNA helicase activity
HPC62_RS02520	COG1012	belongs to the aldehyde dehydrogenase family
HPC62_RS02525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HPC62_RS02540	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS02560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPC62_RS02565	COG1799	cell septum assembly
HPC62_RS02570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPC62_RS02575	COG2234	aminopeptidase activity
HPC62_RS02580	COG1192	Involved in chromosome partitioning
HPC62_RS02590	COG5002	protein histidine kinase activity
HPC62_RS02595	COG0745	RESPONSE REGULATOR receiver
HPC62_RS02600	COG1192	Involved in chromosome partitioning
HPC62_RS02605	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HPC62_RS02620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HPC62_RS02635	COG0492	ferredoxin-NADP+ reductase activity
HPC62_RS02645	COG0360	Binds together with S18 to 16S ribosomal RNA
HPC62_RS02650	COG0179	Fumarylacetoacetate (FAA) hydrolase
HPC62_RS02665	COG1802	Transcriptional regulator
HPC62_RS02670	COG0525	valine-tRNA ligase activity
HPC62_RS02680	COG0194	GDP metabolic process
HPC62_RS02685	COG2052	Domain of unknown function (DUF370)
HPC62_RS02700	COG4221	oxidoreductase activity
HPC62_RS02700	COG3321	synthase
HPC62_RS02700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HPC62_RS02700	COG0604	alcohol dehydrogenase
HPC62_RS02705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS02710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPC62_RS02720	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPC62_RS02720	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HPC62_RS02725	COG0454	-acetyltransferase
HPC62_RS02760	COG0583	DNA-binding transcription factor activity
HPC62_RS02770	COG0668	transmembrane transport
HPC62_RS02790	COG2226	methyltransferase
HPC62_RS02800	COG0720	synthase
HPC62_RS02805	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS02815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPC62_RS02820	COG1045	serine acetyltransferase
HPC62_RS02825	COG0516	GMP reductase activity
HPC62_RS02825	COG0517	IMP dehydrogenase activity
HPC62_RS02835	COG0450	alkyl hydroperoxide reductase
HPC62_RS02840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HPC62_RS02845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPC62_RS02850	COG3409	Peptidoglycan-binding domain 1 protein
HPC62_RS02850	COG3429	Glucose-6-phosphate dehydrogenase subunit
HPC62_RS02905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HPC62_RS02920	COG1429	ligase activity, forming nitrogen-metal bonds
HPC62_RS02930	COG0459	protein refolding
HPC62_RS02935	COG0516	GMP reductase activity
HPC62_RS02960	COG0083	homoserine kinase activity
HPC62_RS02965	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HPC62_RS02970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HPC62_RS03005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HPC62_RS03035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HPC62_RS03040	COG1573	uracil-dna glycosylase
HPC62_RS03045	COG1252	NADH dehydrogenase
HPC62_RS03065	COG0071	Belongs to the small heat shock protein (HSP20) family
HPC62_RS03075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPC62_RS03080	COG3594	Acyltransferase
HPC62_RS03090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HPC62_RS03105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPC62_RS03105	COG0072	phenylalanine-tRNA ligase activity
HPC62_RS03110	COG0515	serine threonine protein kinase
HPC62_RS03110	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS03125	COG0515	serine threonine protein kinase
HPC62_RS03135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPC62_RS03145	COG2046	Belongs to the sulfate adenylyltransferase family
HPC62_RS03155	COG1266	CAAX protease self-immunity
HPC62_RS03165	COG0456	acetyltransferase
HPC62_RS03175	COG0564	pseudouridine synthase activity
HPC62_RS03195	COG0237	dephospho-CoA kinase activity
HPC62_RS03200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HPC62_RS03205	COG1413	lyase activity
HPC62_RS03210	COG1413	lyase activity
HPC62_RS03215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPC62_RS03220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPC62_RS03225	COG0237	dephospho-CoA kinase activity
HPC62_RS03230	COG0237	dephospho-CoA kinase activity
HPC62_RS03235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_RS03240	COG0217	transcriptional regulatory protein
HPC62_RS03250	COG0784	Response regulator, receiver
HPC62_RS03255	COG5002	protein histidine kinase activity
HPC62_RS03255	COG0784	Response regulator, receiver
HPC62_RS03255	COG2205	protein histidine kinase activity
HPC62_RS03270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPC62_RS03275	COG0420	3'-5' exonuclease activity
HPC62_RS03285	COG0424	maF-like protein
HPC62_RS03290	COG2814	Major facilitator Superfamily
HPC62_RS03315	COG0701	Predicted permease
HPC62_RS03355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPC62_RS03360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPC62_RS03390	COG0138	bifunctional purine biosynthesis protein purh
HPC62_RS03400	COG3536	Protein conserved in bacteria
HPC62_RS03425	COG1480	7TM receptor with intracellular HD hydrolase
HPC62_RS03445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HPC62_RS03455	COG2197	response regulator
HPC62_RS03460	COG1309	transcriptional regulator
HPC62_RS03470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPC62_RS03470	COG2169	Transcriptional regulator
HPC62_RS03490	COG0765	amino acid transport
HPC62_RS03495	COG4597	amino acid ABC transporter
HPC62_RS03500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPC62_RS03555	COG0420	3'-5' exonuclease activity
HPC62_RS03590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HPC62_RS03605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HPC62_RS03610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPC62_RS03625	COG1842	Phage shock protein A
HPC62_RS03630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HPC62_RS03635	COG4565	transcriptional regulatory protein
HPC62_RS03640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HPC62_RS03720	COG1366	Belongs to the anti-sigma-factor antagonist family
HPC62_RS03735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HPC62_RS03740	COG0131	Imidazoleglycerol-phosphate dehydratase
HPC62_RS03745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPC62_RS03765	COG0598	Magnesium transport protein CorA
HPC62_RS03770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPC62_RS03775	COG0601	transmembrane transport
HPC62_RS03780	COG1397	ADP-ribosylglycohydrolase
HPC62_RS03790	COG0745	RESPONSE REGULATOR receiver
HPC62_RS03800	COG0515	serine threonine protein kinase
HPC62_RS03800	COG3266	domain, Protein
HPC62_RS03810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HPC62_RS03815	COG0412	Dienelactone hydrolase
HPC62_RS03820	COG3384	dioxygenase
HPC62_RS03850	COG2319	Wd-40 repeat
HPC62_RS03855	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPC62_RS03870	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS03880	COG0250	Participates in transcription elongation, termination and antitermination
HPC62_RS03885	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPC62_RS03890	COG0081	regulation of translation
HPC62_RS03895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPC62_RS03900	COG0222	ribosome binding
HPC62_RS03905	COG3977	Valine--pyruvate aminotransferase
HPC62_RS03910	COG0170	dolichyl monophosphate biosynthetic process
HPC62_RS03920	COG1509	lysine 2,3-aminomutase activity
HPC62_RS03940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HPC62_RS03945	COG1309	transcriptional regulator
HPC62_RS03950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPC62_RS03960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HPC62_RS03965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HPC62_RS03970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HPC62_RS03980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HPC62_RS03980	COG0617	tRNA 3'-terminal CCA addition
HPC62_RS03980	COG0517	IMP dehydrogenase activity
HPC62_RS04010	COG0137	argininosuccinate synthase activity
HPC62_RS04025	COG2860	membrane
HPC62_RS04035	COG0861	Integral membrane protein TerC family
HPC62_RS04040	COG0826	peptidase U32
HPC62_RS04050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPC62_RS04055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HPC62_RS04070	COG1543	Belongs to the glycosyl hydrolase 57 family
HPC62_RS04095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HPC62_RS04110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HPC62_RS04120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPC62_RS04125	COG0632	four-way junction helicase activity
HPC62_RS04130	COG0312	modulator of DNA gyrase
HPC62_RS04140	COG0542	response to heat
HPC62_RS04150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HPC62_RS04150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPC62_RS04200	COG0123	including yeast histone deacetylase and acetoin utilization protein
HPC62_RS04205	COG1305	Transglutaminase-like
HPC62_RS04210	COG0768	penicillin binding
HPC62_RS04215	COG1218	3'(2'),5'-bisphosphate nucleotidase
HPC62_RS04220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS04235	COG1222	aaa ATPase
HPC62_RS04245	COG0346	lactoylglutathione lyase activity
HPC62_RS04260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPC62_RS04265	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HPC62_RS04280	COG1733	regulation of RNA biosynthetic process
HPC62_RS04290	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HPC62_RS04295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HPC62_RS04295	COG0519	Catalyzes the synthesis of GMP from XMP
HPC62_RS04300	COG0515	serine threonine protein kinase
HPC62_RS04310	COG0589	response to stress
HPC62_RS04315	COG0126	phosphoglycerate kinase activity
HPC62_RS04320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPC62_RS04335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPC62_RS04335	COG0758	DNA mediated transformation
HPC62_RS04340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPC62_RS04370	COG0024	Methionine aminopeptidase
HPC62_RS04400	COG1691	(AIR) carboxylase
HPC62_RS04410	COG1620	l-lactate permease
HPC62_RS04435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPC62_RS04475	COG0297	glycogen (starch) synthase activity
HPC62_RS04480	COG0500	methyltransferase
HPC62_RS04490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPC62_RS04505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPC62_RS04550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPC62_RS04555	COG0564	pseudouridine synthase activity
HPC62_RS04570	COG0167	dihydroorotate dehydrogenase activity
HPC62_RS04585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPC62_RS04590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPC62_RS04595	COG0085	RNA polymerase activity
HPC62_RS04600	COG0084	hydrolase, TatD family'
HPC62_RS04605	COG0268	Binds directly to 16S ribosomal RNA
HPC62_RS04610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPC62_RS04620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HPC62_RS04635	COG1366	Belongs to the anti-sigma-factor antagonist family
HPC62_RS04640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPC62_RS04645	COG1530	ribonuclease E activity
HPC62_RS04650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPC62_RS04665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HPC62_RS04670	COG1324	tolerance protein
HPC62_RS04680	COG0745	RESPONSE REGULATOR receiver
HPC62_RS04690	COG0569	domain protein
HPC62_RS04690	COG2985	domain, Protein
HPC62_RS04705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HPC62_RS04710	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HPC62_RS04720	COG2217	Heavy metal translocating P-type atpase
HPC62_RS04730	COG0456	acetyltransferase
HPC62_RS04740	COG1063	alcohol dehydrogenase
HPC62_RS04745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HPC62_RS04750	COG0395	ABC-type sugar transport system, permease component
HPC62_RS04755	COG0667	Aldo Keto reductase
HPC62_RS04765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPC62_RS04780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HPC62_RS04785	COG0793	Belongs to the peptidase S41A family
HPC62_RS04790	COG1078	dGTPase activity
HPC62_RS04795	COG0842	Transport permease protein
HPC62_RS04800	COG1131	(ABC) transporter
HPC62_RS04805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS04810	COG0003	Pfam Anion-transporting ATPase
HPC62_RS04820	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HPC62_RS04825	COG1490	D-aminoacyl-tRNA deacylase activity
HPC62_RS04830	COG2205	protein histidine kinase activity
HPC62_RS04840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS04860	COG0445	tRNA wobble uridine modification
HPC62_RS04895	COG0751	glycine-tRNA ligase activity
HPC62_RS04920	COG0587	DNA-directed DNA polymerase activity
HPC62_RS04930	COG0587	DNA-directed DNA polymerase activity
HPC62_RS04935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HPC62_RS04950	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HPC62_RS04955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPC62_RS05020	COG1840	ABC-type Fe3 transport system, periplasmic component
HPC62_RS05025	COG3842	ATPase activity
HPC62_RS05045	COG0857	belongs to the CobB CobQ family
HPC62_RS05045	COG0280	phosphate acetyltransferase
HPC62_RS05050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPC62_RS05090	COG1121	(ABC) transporter
HPC62_RS05095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HPC62_RS05105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS05130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPC62_RS05140	COG2095	MarC family integral membrane protein
HPC62_RS05165	COG1002	Type II restriction enzyme, methylase subunits
HPC62_RS05240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HPC62_RS05250	COG1619	proteins homologs of microcin C7 resistance protein MccF
HPC62_RS05255	COG1361	Conserved repeat domain
HPC62_RS05280	COG2082	Precorrin-8x methylmutase
HPC62_RS05285	COG0772	Belongs to the SEDS family
HPC62_RS05305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPC62_RS05315	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HPC62_RS05320	COG2211	Major facilitator Superfamily
HPC62_RS05340	COG0484	heat shock protein binding
HPC62_RS05345	COG0740	serine-type endopeptidase activity
HPC62_RS05350	COG0740	serine-type endopeptidase activity
HPC62_RS05355	COG0740	serine-type endopeptidase activity
HPC62_RS05360	COG2304	oxidoreductase activity
HPC62_RS05365	COG1136	(ABC) transporter
HPC62_RS05375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HPC62_RS05380	COG2264	protein methyltransferase activity
HPC62_RS05385	COG1187	pseudouridine synthase activity
HPC62_RS05395	COG1640	4-alpha-glucanotransferase
HPC62_RS05410	COG0730	response to heat
HPC62_RS05415	COG0156	8-amino-7-oxononanoate synthase activity
HPC62_RS05430	COG0649	NAD binding
HPC62_RS05440	COG1575	Belongs to the MenA family. Type 1 subfamily
HPC62_RS05465	COG2003	Belongs to the UPF0758 family
HPC62_RS05485	COG1166	arginine decarboxylase activity
HPC62_RS05490	COG0105	UTP biosynthetic process
HPC62_RS05500	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS05500	COG0515	serine threonine protein kinase
HPC62_RS05525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HPC62_RS05530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPC62_RS05540	COG3842	ATPase activity
HPC62_RS05550	COG0395	ABC-type sugar transport system, permease component
HPC62_RS05585	COG1126	abc transporter atp-binding protein
HPC62_RS05590	COG0765	amino acid transport
HPC62_RS05625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPC62_RS05635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPC62_RS05640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HPC62_RS05650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPC62_RS05655	COG4208	sulfate ABC transporter
HPC62_RS05660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HPC62_RS05665	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HPC62_RS05670	COG0523	cobalamin synthesis protein
HPC62_RS05675	COG0628	permease
HPC62_RS05680	COG0527	aspartate kinase activity
HPC62_RS05685	COG0363	glucosamine-6-phosphate deaminase activity
HPC62_RS05705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPC62_RS05710	COG0552	protein localization to endoplasmic reticulum
HPC62_RS05725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HPC62_RS05745	COG1077	Cell shape determining protein MreB Mrl
HPC62_RS05750	COG0629	single-stranded DNA binding
HPC62_RS05760	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HPC62_RS05765	COG0768	penicillin binding
HPC62_RS05770	COG3842	ATPase activity
HPC62_RS05775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HPC62_RS05780	COG1176	ABC-type spermidine putrescine transport system, permease component I
HPC62_RS05785	COG1177	transmembrane transport
HPC62_RS05790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPC62_RS05795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HPC62_RS05800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPC62_RS05825	COG2321	neutral zinc metallopeptidase
HPC62_RS05840	COG0275	rRNA processing
HPC62_RS05845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPC62_RS05855	COG0723	plastoquinol--plastocyanin reductase activity
HPC62_RS05865	COG0805	protein transport
HPC62_RS05875	COG1716	ATPase activity
HPC62_RS05900	COG0740	serine-type endopeptidase activity
HPC62_RS05920	COG1191	sigma factor activity
HPC62_RS05925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPC62_RS05935	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HPC62_RS05935	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HPC62_RS05950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPC62_RS05960	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HPC62_RS05970	COG1981	membrane
HPC62_RS05990	COG0405	Gamma-glutamyltransferase
HPC62_RS06040	COG4243	Vitamin k epoxide reductase
HPC62_RS06045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HPC62_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPC62_RS06080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPC62_RS06085	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS06090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS06100	COG0628	permease
HPC62_RS06105	COG0484	heat shock protein binding
HPC62_RS06110	COG0443	Heat shock 70 kDa protein
HPC62_RS06115	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HPC62_RS06125	COG0515	serine threonine protein kinase
HPC62_RS06125	COG3266	domain, Protein
HPC62_RS06145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HPC62_RS06145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HPC62_RS06170	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPC62_RS06190	COG0659	secondary active sulfate transmembrane transporter activity
HPC62_RS06195	COG0640	Transcriptional regulator
HPC62_RS06220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS06250	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HPC62_RS06275	COG0792	nuclease activity
HPC62_RS06305	COG0612	Peptidase, M16
HPC62_RS06315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPC62_RS06335	COG3956	TIGRFAM MazG family protein
HPC62_RS06345	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS06350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HPC62_RS06365	COG0542	response to heat
HPC62_RS06370	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS06370	COG0515	serine threonine protein kinase
HPC62_RS06395	COG0288	reversible hydration of carbon dioxide
HPC62_RS06400	COG4178	(ABC) transporter
HPC62_RS06405	COG0285	dihydrofolate synthase activity
HPC62_RS06440	COG0515	serine threonine protein kinase
HPC62_RS06445	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS06485	COG0277	FAD linked oxidase domain protein
HPC62_RS06540	COG1175	transmembrane transport
HPC62_RS06545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPC62_RS06575	COG0745	RESPONSE REGULATOR receiver
HPC62_RS06580	COG5002	protein histidine kinase activity
HPC62_RS06620	COG3385	transposase activity
HPC62_RS06625	COG0556	nucleotide-excision repair
HPC62_RS06670	COG3385	transposase activity
HPC62_RS06715	COG1732	Glycine betaine
HPC62_RS06740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HPC62_RS06745	COG0484	heat shock protein binding
HPC62_RS06770	COG5000	phosphorelay sensor kinase activity
HPC62_RS06770	COG5002	protein histidine kinase activity
HPC62_RS06790	COG0335	large ribosomal subunit rRNA binding
HPC62_RS06810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPC62_RS06840	COG0589	response to stress
HPC62_RS06845	COG0824	Thioesterase
HPC62_RS06850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPC62_RS06855	COG0402	S-adenosylhomocysteine deaminase activity
HPC62_RS06865	COG2205	protein histidine kinase activity
HPC62_RS06870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HPC62_RS06885	COG2233	PERMEase
HPC62_RS06915	COG1295	ribonuclease BN
HPC62_RS06940	COG1136	(ABC) transporter
HPC62_RS06980	COG0768	penicillin binding
HPC62_RS07020	COG1472	Belongs to the glycosyl hydrolase 3 family
HPC62_RS07075	COG0697	spore germination
HPC62_RS07080	COG3237	CsbD-like
HPC62_RS07125	COG0107	imidazoleglycerol-phosphate synthase activity
HPC62_RS07135	COG2363	Small membrane protein
HPC62_RS07145	COG0215	cysteine-tRNA ligase activity
HPC62_RS07165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPC62_RS07170	COG0587	DNA-directed DNA polymerase activity
HPC62_RS07175	COG0745	RESPONSE REGULATOR receiver
HPC62_RS07180	COG0318	PFAM AMP-dependent synthetase and ligase
HPC62_RS07185	COG4948	Mandelate Racemase Muconate Lactonizing
HPC62_RS07190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPC62_RS07200	COG0829	nickel cation binding
HPC62_RS07240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPC62_RS07260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HPC62_RS07275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPC62_RS07285	COG2255	four-way junction helicase activity
HPC62_RS07300	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS07305	COG0668	transmembrane transport
HPC62_RS07340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPC62_RS07350	COG3654	unkown
HPC62_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS07365	COG0066	3-isopropylmalate dehydratase activity
HPC62_RS07375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPC62_RS07390	COG1309	transcriptional regulator
HPC62_RS07400	COG2385	sporulation resulting in formation of a cellular spore
HPC62_RS07405	COG3608	succinylglutamate desuccinylase aspartoacylase
HPC62_RS07420	COG0681	Belongs to the peptidase S26 family
HPC62_RS07435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPC62_RS07445	COG0613	PHP domain protein
HPC62_RS07450	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HPC62_RS07460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPC62_RS07465	COG0187	DNA topoisomerase II activity
HPC62_RS07465	COG1372	Participates in initiation and elongation during chromosome replication
HPC62_RS07485	COG2144	transferase activity, transferring acyl groups
HPC62_RS07515	COG2072	flavoprotein involved in K transport
HPC62_RS07520	COG1012	belongs to the aldehyde dehydrogenase family
HPC62_RS07535	COG0514	ATP-dependent DNA helicase (RecQ)
HPC62_RS07540	COG0752	glycyl-tRNA synthetase alpha subunit
HPC62_RS07545	COG0359	binds to the 23S rRNA
HPC62_RS07550	COG1372	Participates in initiation and elongation during chromosome replication
HPC62_RS07550	COG0305	Participates in initiation and elongation during chromosome replication
HPC62_RS07575	COG0488	(ABC) transporter
HPC62_RS07580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPC62_RS07605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPC62_RS07620	COG2010	Cytochrome c
HPC62_RS07625	COG0745	RESPONSE REGULATOR receiver
HPC62_RS07635	COG0483	inositol monophosphate 1-phosphatase activity
HPC62_RS07640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPC62_RS07650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPC62_RS07660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPC62_RS07665	COG0134	indole-3-glycerol-phosphate synthase activity
HPC62_RS07695	COG0746	molybdenum cofactor guanylyltransferase activity
HPC62_RS07735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS07740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPC62_RS07745	COG3937	granule-associated protein
HPC62_RS07750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HPC62_RS07755	COG0631	protein serine/threonine phosphatase activity
HPC62_RS07765	COG4251	negative regulation of phosphorylation
HPC62_RS07790	COG0784	Response regulator, receiver
HPC62_RS07790	COG2198	Histidine kinase
HPC62_RS07790	COG2198	Histidine kinase
HPC62_RS07790	COG0784	Response regulator, receiver
HPC62_RS07790	COG0643	Histidine kinase
HPC62_RS07790	COG0643	Histidine kinase
HPC62_RS07795	COG0840	transmembrane signaling receptor activity
HPC62_RS07825	COG0129	dihydroxy-acid dehydratase activity
HPC62_RS07870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HPC62_RS07875	COG0724	RNA recognition motif
HPC62_RS07880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HPC62_RS07885	COG0028	Belongs to the TPP enzyme family
HPC62_RS07895	COG0561	phosphatase activity
HPC62_RS07915	COG2081	HI0933 family
HPC62_RS07925	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS07945	COG1049	propionate catabolic process, 2-methylcitrate cycle
HPC62_RS07960	COG0067	glutamate synthase
HPC62_RS07960	COG0069	glutamate synthase activity
HPC62_RS07960	COG0070	glutamate synthase
HPC62_RS07985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPC62_RS08005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS08015	COG0372	Belongs to the citrate synthase family
HPC62_RS08035	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HPC62_RS08045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HPC62_RS08050	COG0569	domain protein
HPC62_RS08055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HPC62_RS08060	COG2226	methyltransferase
HPC62_RS08085	COG0363	glucosamine-6-phosphate deaminase activity
HPC62_RS08105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HPC62_RS08110	COG1982	Orn Lys Arg decarboxylase major
HPC62_RS08115	COG5002	protein histidine kinase activity
HPC62_RS08125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HPC62_RS08130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPC62_RS08140	COG0109	protoheme IX farnesyltransferase activity
HPC62_RS08150	COG1606	tRNA processing
HPC62_RS08155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HPC62_RS08200	COG0193	aminoacyl-tRNA hydrolase activity
HPC62_RS08205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPC62_RS08215	COG0538	isocitrate dehydrogenase activity
HPC62_RS08230	COG0277	FAD linked oxidase domain protein
HPC62_RS08240	COG0308	aminopeptidase N
HPC62_RS08250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPC62_RS08255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPC62_RS08260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPC62_RS08265	COG0544	peptidyl-prolyl cis-trans isomerase activity
HPC62_RS08270	COG0740	serine-type endopeptidase activity
HPC62_RS08275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPC62_RS08285	COG4279	zinc finger
HPC62_RS08295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS08325	COG0315	cyclic pyranopterin monophosphate synthase activity
HPC62_RS08350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPC62_RS08365	COG2226	methyltransferase
HPC62_RS08390	COG0709	Synthesizes selenophosphate from selenide and ATP
HPC62_RS08395	COG0481	GTPase activity
HPC62_RS08445	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS08450	COG1494	fructose-1,6-bisphosphatase
HPC62_RS08455	COG2099	Precorrin-6x reductase
HPC62_RS08480	COG1940	carbohydrate kinase activity
HPC62_RS08485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HPC62_RS08495	COG1132	(ABC) transporter
HPC62_RS08515	COG2010	Cytochrome c
HPC62_RS08525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HPC62_RS08525	COG0723	plastoquinol--plastocyanin reductase activity
HPC62_RS08535	COG0010	Belongs to the arginase family
HPC62_RS08540	COG0375	protein maturation
HPC62_RS08570	COG1053	succinate dehydrogenase
HPC62_RS08575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPC62_RS08580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPC62_RS08585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPC62_RS08590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPC62_RS08595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPC62_RS08600	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPC62_RS08605	COG0356	it plays a direct role in the translocation of protons across the membrane
HPC62_RS08615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HPC62_RS08620	COG0728	peptidoglycan biosynthetic process
HPC62_RS08625	COG0110	maltose O-acetyltransferase activity
HPC62_RS08635	COG0601	transmembrane transport
HPC62_RS08650	COG0009	L-threonylcarbamoyladenylate synthase
HPC62_RS08675	COG0784	Response regulator, receiver
HPC62_RS08675	COG4191	Histidine kinase
HPC62_RS08705	COG1192	Involved in chromosome partitioning
HPC62_RS08710	COG0415	Belongs to the DNA photolyase family
HPC62_RS08725	COG2203	Gaf domain
HPC62_RS08725	COG3706	GGDEF domain
HPC62_RS08725	COG4251	negative regulation of phosphorylation
HPC62_RS08725	COG5001	Diguanylate cyclase
HPC62_RS08780	COG0415	Belongs to the DNA photolyase family
HPC62_RS08835	COG0436	Aminotransferase
HPC62_RS08845	COG0804	urea catabolic process
HPC62_RS08865	COG5002	protein histidine kinase activity
HPC62_RS08870	COG4191	Histidine kinase
HPC62_RS08875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS08890	COG0058	SHG alpha-glucan phosphorylase activity
HPC62_RS08895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPC62_RS08900	COG0584	glycerophosphoryl diester phosphodiesterase
HPC62_RS08940	COG0848	biopolymer transport protein
HPC62_RS08945	COG0811	peptide transport
HPC62_RS08955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPC62_RS08965	COG0572	uridine kinase
HPC62_RS08970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPC62_RS08975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPC62_RS08995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HPC62_RS09000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPC62_RS09005	COG0321	lipoyl(octanoyl) transferase activity
HPC62_RS09135	COG1595	DNA-templated transcription, initiation
HPC62_RS09140	COG1054	Belongs to the UPF0176 family
HPC62_RS09150	COG2319	Wd-40 repeat
HPC62_RS09150	COG3903	Transcriptional regulator
HPC62_RS09155	COG1744	ABC transporter substrate-binding protein PnrA-like
HPC62_RS09160	COG4603	Belongs to the binding-protein-dependent transport system permease family
HPC62_RS09165	COG1079	Belongs to the binding-protein-dependent transport system permease family
HPC62_RS09175	COG3845	ABC transporter
HPC62_RS09185	COG0017	Asparaginyl-tRNA synthetase
HPC62_RS09245	COG0402	S-adenosylhomocysteine deaminase activity
HPC62_RS09250	COG2177	Part of the ABC transporter FtsEX involved in
HPC62_RS09295	COG0316	Belongs to the HesB IscA family
HPC62_RS09310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPC62_RS09325	COG2239	Acts as a magnesium transporter
HPC62_RS09330	COG1006	Multisubunit Na H antiporter MnhC subunit
HPC62_RS09335	COG0651	ATP synthesis coupled electron transport
HPC62_RS09415	COG0154	amidase activity
HPC62_RS09420	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HPC62_RS09435	COG0659	secondary active sulfate transmembrane transporter activity
HPC62_RS09440	COG0284	orotidine-5'-phosphate decarboxylase activity
HPC62_RS09475	COG0412	Dienelactone hydrolase
HPC62_RS09490	COG2831	hemolysin activation secretion protein
HPC62_RS09505	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HPC62_RS09515	COG1496	oxidoreductase activity
HPC62_RS09520	COG4251	negative regulation of phosphorylation
HPC62_RS09530	COG1032	radical SAM domain protein
HPC62_RS09540	COG0124	histidyl-tRNA synthetase
HPC62_RS09550	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPC62_RS09570	COG0765	amino acid transport
HPC62_RS09615	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPC62_RS09620	COG2197	response regulator
HPC62_RS09630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HPC62_RS09640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HPC62_RS09645	COG0783	Belongs to the Dps family
HPC62_RS09730	COG0776	regulation of translation
HPC62_RS09735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPC62_RS09740	COG1331	Highly conserved protein containing a thioredoxin domain
HPC62_RS09765	COG4636	protein conserved in cyanobacteria
HPC62_RS09770	COG5002	protein histidine kinase activity
HPC62_RS09775	COG0596	Alpha beta hydrolase
HPC62_RS09785	COG0018	arginyl-trna synthetase
HPC62_RS09800	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPC62_RS09815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HPC62_RS09820	COG2205	protein histidine kinase activity
HPC62_RS09820	COG2202	Pas domain
HPC62_RS09850	COG0347	Belongs to the P(II) protein family
HPC62_RS09855	COG0095	Lipoate-protein ligase
HPC62_RS09880	COG3852	Histidine kinase
HPC62_RS09885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPC62_RS09895	COG0312	modulator of DNA gyrase
HPC62_RS09910	COG0242	peptide deformylase activity
HPC62_RS09940	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HPC62_RS09990	COG3119	arylsulfatase activity
HPC62_RS10020	COG0596	Alpha beta hydrolase
HPC62_RS10025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HPC62_RS10045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HPC62_RS10065	COG0802	atpase or kinase
HPC62_RS10070	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPC62_RS10095	COG1217	gtp-binding protein TYPA
HPC62_RS10105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPC62_RS10115	COG0717	Belongs to the dCTP deaminase family
HPC62_RS10140	COG2226	methyltransferase
HPC62_RS10150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPC62_RS10155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPC62_RS10160	COG1696	Membrane protein involved in D-alanine export
HPC62_RS10195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPC62_RS10200	COG0473	3-isopropylmalate dehydrogenase activity
HPC62_RS10210	COG1131	(ABC) transporter
HPC62_RS10225	COG0123	including yeast histone deacetylase and acetoin utilization protein
HPC62_RS10250	COG1994	Peptidase M50
HPC62_RS10260	COG0784	Response regulator, receiver
HPC62_RS10260	COG2205	protein histidine kinase activity
HPC62_RS10260	COG5002	protein histidine kinase activity
HPC62_RS10265	COG0745	RESPONSE REGULATOR receiver
HPC62_RS10285	COG0456	acetyltransferase
HPC62_RS10300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPC62_RS10305	COG0745	RESPONSE REGULATOR receiver
HPC62_RS10310	COG0416	fatty acid biosynthetic process
HPC62_RS10315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPC62_RS10320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HPC62_RS10325	COG0318	PFAM AMP-dependent synthetase and ligase
HPC62_RS10325	COG0204	Acyl-transferase
HPC62_RS10340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HPC62_RS10340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HPC62_RS10365	COG5001	Diguanylate cyclase
HPC62_RS10365	COG1716	ATPase activity
HPC62_RS10380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPC62_RS10385	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HPC62_RS10390	COG1234	tRNA 3'-trailer cleavage
HPC62_RS10395	COG0196	riboflavin kinase activity
HPC62_RS10420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPC62_RS10425	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPC62_RS10430	COG0019	diaminopimelate decarboxylase activity
HPC62_RS10435	COG0456	acetyltransferase
HPC62_RS10440	COG0542	response to heat
HPC62_RS10445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPC62_RS10450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPC62_RS10475	COG1214	PFAM Peptidase M22, glycoprotease
HPC62_RS10530	COG4149	molybdate abc transporter
HPC62_RS10535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HPC62_RS10540	COG0725	ABC transporter, periplasmic molybdate-binding protein
HPC62_RS10550	COG2091	lysine biosynthetic process via aminoadipic acid
HPC62_RS10555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPC62_RS10560	COG0473	3-isopropylmalate dehydrogenase activity
HPC62_RS10565	COG1073	alpha beta
HPC62_RS10585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPC62_RS10585	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS10620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPC62_RS10625	COG0604	alcohol dehydrogenase
HPC62_RS10625	COG3321	synthase
HPC62_RS10655	COG3629	intracellular signal transduction
HPC62_RS10655	COG3903	Transcriptional regulator
HPC62_RS10675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPC62_RS10680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HPC62_RS10685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPC62_RS10725	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPC62_RS10740	COG0180	Tryptophanyl-tRNA synthetase
HPC62_RS10755	COG5002	protein histidine kinase activity
HPC62_RS10760	COG0745	RESPONSE REGULATOR receiver
HPC62_RS10770	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HPC62_RS10790	COG0297	glycogen (starch) synthase activity
HPC62_RS10800	COG0181	hydroxymethylbilane synthase activity
HPC62_RS10805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HPC62_RS10810	COG0860	N-Acetylmuramoyl-L-alanine amidase
HPC62_RS10815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPC62_RS10845	COG0612	Peptidase, M16
HPC62_RS10850	COG3001	Fructosamine kinase
HPC62_RS10860	COG0450	alkyl hydroperoxide reductase
HPC62_RS10870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPC62_RS10875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HPC62_RS10890	COG3932	Exopolysaccharide synthesis, ExoD
HPC62_RS10895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HPC62_RS10905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HPC62_RS10915	COG0432	Pfam Uncharacterised protein family UPF0047
HPC62_RS10930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPC62_RS10930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPC62_RS10935	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HPC62_RS10940	COG1408	metallophosphoesterase
HPC62_RS10945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS10950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPC62_RS10955	COG0719	Fe-S assembly protein
HPC62_RS10960	COG0396	ATPase activity
HPC62_RS10970	COG0719	Fe-S assembly protein
HPC62_RS10975	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
HPC62_RS11015	COG5001	Diguanylate cyclase
HPC62_RS11020	COG4581	dead DEAH box helicase
HPC62_RS11025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPC62_RS11030	COG0495	leucyl-tRNA aminoacylation
HPC62_RS11035	COG0798	PFAM Bile acid sodium symporter
HPC62_RS11045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HPC62_RS11050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS11055	COG0640	Transcriptional regulator
HPC62_RS11060	COG0513	Belongs to the DEAD box helicase family
HPC62_RS11065	COG4942	peptidase
HPC62_RS11075	COG1522	sequence-specific DNA binding
HPC62_RS11080	COG0501	Belongs to the peptidase M48B family
HPC62_RS11085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HPC62_RS11110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPC62_RS11120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPC62_RS11200	COG3385	transposase activity
HPC62_RS11210	COG0039	L-malate dehydrogenase activity
HPC62_RS11240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HPC62_RS11245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HPC62_RS11250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPC62_RS11300	COG3852	Histidine kinase
HPC62_RS11320	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS11320	COG0515	serine threonine protein kinase
HPC62_RS11330	COG0617	tRNA 3'-terminal CCA addition
HPC62_RS11345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPC62_RS11350	COG0686	Belongs to the AlaDH PNT family
HPC62_RS11360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPC62_RS11370	COG5002	protein histidine kinase activity
HPC62_RS11380	COG3128	pkhd-type hydroxylase
HPC62_RS11395	COG3385	transposase activity
HPC62_RS11430	COG0446	pyridine nucleotide-disulphide oxidoreductase
HPC62_RS11455	COG3385	transposase activity
HPC62_RS11485	COG0731	radical SAM domain protein
HPC62_RS11505	COG0789	Transcriptional regulator
HPC62_RS11510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HPC62_RS11520	COG1271	oxidase subunit
HPC62_RS11525	COG0730	response to heat
HPC62_RS11530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPC62_RS11545	COG0446	pyridine nucleotide-disulphide oxidoreductase
HPC62_RS11570	COG0500	methyltransferase
HPC62_RS11580	COG0716	FMN binding
HPC62_RS11595	COG0316	Belongs to the HesB IscA family
HPC62_RS11600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HPC62_RS11610	COG5420	small protein containing a coiled-coil domain
HPC62_RS11620	COG1045	serine acetyltransferase
HPC62_RS11635	COG1104	cysteine desulfurase activity
HPC62_RS11645	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HPC62_RS11650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS11655	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS11660	COG5554	nitrogen fixation
HPC62_RS11670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HPC62_RS11685	COG0783	Belongs to the Dps family
HPC62_RS11690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPC62_RS11765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HPC62_RS11850	COG4251	negative regulation of phosphorylation
HPC62_RS11860	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HPC62_RS11870	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HPC62_RS11870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPC62_RS11875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HPC62_RS11880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS11895	COG1088	dTDP-glucose 4,6-dehydratase activity
HPC62_RS11935	COG0463	Glycosyl transferase, family 2
HPC62_RS11945	COG4451	ribulose bisphosphate carboxylase, small
HPC62_RS11955	COG1850	ribulose-bisphosphate carboxylase activity
HPC62_RS11965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HPC62_RS11970	COG1131	(ABC) transporter
HPC62_RS11975	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HPC62_RS11980	COG1649	PFAM Uncharacterised BCR, COG1649
HPC62_RS11985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPC62_RS11985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPC62_RS11990	COG2326	polyphosphate kinase activity
HPC62_RS11995	COG1376	ErfK ybiS ycfS ynhG family protein
HPC62_RS12000	COG0534	Mate efflux family protein
HPC62_RS12020	COG0825	malonyl-CoA metabolic process
HPC62_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS12035	COG0302	gtp cyclohydrolase
HPC62_RS12055	COG3659	wide pore channel activity
HPC62_RS12060	COG0463	Glycosyl transferase, family 2
HPC62_RS12085	COG2319	Wd-40 repeat
HPC62_RS12085	COG1672	PFAM Archaeal ATPase
HPC62_RS12130	COG0154	amidase activity
HPC62_RS12165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPC62_RS12180	COG3046	protein related to deoxyribodipyrimidine photolyase
HPC62_RS12190	COG1752	Esterase of the alpha-beta hydrolase superfamily
HPC62_RS12195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPC62_RS12200	COG0419	ATPase involved in DNA repair
HPC62_RS12215	COG0850	regulation of cytokinetic process
HPC62_RS12220	COG2894	cell division
HPC62_RS12225	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HPC62_RS12250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS12255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS12260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS12290	COG0110	maltose O-acetyltransferase activity
HPC62_RS12295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HPC62_RS12305	COG0515	serine threonine protein kinase
HPC62_RS12320	COG3409	Peptidoglycan-binding domain 1 protein
HPC62_RS12320	COG0860	N-Acetylmuramoyl-L-alanine amidase
HPC62_RS12325	COG0426	domain, Protein
HPC62_RS12325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPC62_RS12340	COG0426	domain, Protein
HPC62_RS12340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPC62_RS12350	COG0484	heat shock protein binding
HPC62_RS12430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HPC62_RS12440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HPC62_RS12445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HPC62_RS12450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPC62_RS12455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPC62_RS12485	COG0521	Mo-molybdopterin cofactor biosynthetic process
HPC62_RS12535	COG2188	Transcriptional regulator
HPC62_RS12540	COG1797	cobyrinic acid a,c-diamide synthase activity
HPC62_RS12550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPC62_RS12560	COG1596	polysaccharide export
HPC62_RS12590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HPC62_RS12595	COG0025	NhaP-type Na H and K H
HPC62_RS12600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HPC62_RS12600	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HPC62_RS12605	COG0163	prenyltransferase activity
HPC62_RS12610	COG3118	belongs to the thioredoxin family
HPC62_RS12615	COG1842	Phage shock protein A
HPC62_RS12625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS12630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPC62_RS12640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HPC62_RS12645	COG0579	oxidoreductase
HPC62_RS12650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPC62_RS12660	COG0460	homoserine dehydrogenase
HPC62_RS12670	COG0142	geranyltranstransferase activity
HPC62_RS12675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HPC62_RS12680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HPC62_RS12700	COG1695	Transcriptional regulator
HPC62_RS12715	COG1122	ATPase activity
HPC62_RS12720	COG0357	Ribosomal RNA small subunit methyltransferase G
HPC62_RS12725	COG2203	Gaf domain
HPC62_RS12725	COG3706	GGDEF domain
HPC62_RS12725	COG4251	negative regulation of phosphorylation
HPC62_RS12725	COG5001	Diguanylate cyclase
HPC62_RS12730	COG3842	ATPase activity
HPC62_RS12735	COG5001	Diguanylate cyclase
HPC62_RS12740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HPC62_RS12750	COG0745	RESPONSE REGULATOR receiver
HPC62_RS12755	COG3411	Ferredoxin
HPC62_RS12760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HPC62_RS12770	COG0343	queuine tRNA-ribosyltransferase activity
HPC62_RS12775	COG0501	Belongs to the peptidase M48B family
HPC62_RS12780	COG1196	nuclear chromosome segregation
HPC62_RS12790	COG5001	Diguanylate cyclase
HPC62_RS12790	COG2203	Gaf domain
HPC62_RS12790	COG3706	GGDEF domain
HPC62_RS12790	COG4251	negative regulation of phosphorylation
HPC62_RS12795	COG1162	GTPase activity
HPC62_RS12805	COG0484	heat shock protein binding
HPC62_RS12820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPC62_RS12825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HPC62_RS12835	COG1459	type II secretion system
HPC62_RS12855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPC62_RS12860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HPC62_RS12900	COG2261	transglycosylase associated protein
HPC62_RS12930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HPC62_RS12935	COG2211	Major facilitator Superfamily
HPC62_RS12950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HPC62_RS12970	COG1968	undecaprenyl-diphosphatase activity
HPC62_RS12990	COG3206	protein involved in exopolysaccharide biosynthesis
HPC62_RS12990	COG0489	protein tyrosine kinase activity
HPC62_RS13020	COG4555	ABC transporter
HPC62_RS13040	COG0408	coproporphyrinogen oxidase activity
HPC62_RS13060	COG0489	protein tyrosine kinase activity
HPC62_RS13060	COG3206	protein involved in exopolysaccharide biosynthesis
HPC62_RS13065	COG1132	(ABC) transporter
HPC62_RS13070	COG1216	Glycosyl transferase, family 2
HPC62_RS13075	COG1216	Glycosyl transferase, family 2
HPC62_RS13080	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13105	COG0505	Belongs to the CarA family
HPC62_RS13120	COG0459	protein refolding
HPC62_RS13125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPC62_RS13130	COG1254	Belongs to the acylphosphatase family
HPC62_RS13135	COG0297	glycogen (starch) synthase activity
HPC62_RS13140	COG1713	HD superfamily hydrolase involved in NAD metabolism
HPC62_RS13145	COG0799	negative regulation of ribosome biogenesis
HPC62_RS13160	COG1007	ATP synthesis coupled electron transport
HPC62_RS13165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPC62_RS13175	COG1132	(ABC) transporter
HPC62_RS13180	COG1045	serine acetyltransferase
HPC62_RS13215	COG1596	polysaccharide export
HPC62_RS13220	COG0489	protein tyrosine kinase activity
HPC62_RS13225	COG0837	glucose binding
HPC62_RS13245	COG0714	Associated with various cellular activities
HPC62_RS13255	COG2234	aminopeptidase activity
HPC62_RS13260	COG0667	Aldo Keto reductase
HPC62_RS13270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HPC62_RS13285	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
HPC62_RS13320	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13330	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13335	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13345	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13365	COG1132	(ABC) transporter
HPC62_RS13370	COG0489	protein tyrosine kinase activity
HPC62_RS13420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPC62_RS13425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HPC62_RS13430	COG0237	dephospho-CoA kinase activity
HPC62_RS13450	COG0739	heme binding
HPC62_RS13480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPC62_RS13485	COG0455	bacterial-type flagellum organization
HPC62_RS13495	COG2205	protein histidine kinase activity
HPC62_RS13505	COG4251	negative regulation of phosphorylation
HPC62_RS13510	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HPC62_RS13535	COG0784	Response regulator, receiver
HPC62_RS13535	COG2198	Histidine kinase
HPC62_RS13535	COG5002	protein histidine kinase activity
HPC62_RS13550	COG2319	Wd-40 repeat
HPC62_RS13550	COG1672	PFAM Archaeal ATPase
HPC62_RS13560	COG0460	homoserine dehydrogenase
HPC62_RS13575	COG0673	inositol 2-dehydrogenase activity
HPC62_RS13580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HPC62_RS13595	COG2267	carboxylic ester hydrolase activity
HPC62_RS13600	COG1834	amidinotransferase
HPC62_RS13630	COG2346	COG2346, Truncated hemoglobins
HPC62_RS13650	COG1489	DNA binding
HPC62_RS13660	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13665	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS13690	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HPC62_RS13695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS13755	COG0406	alpha-ribazole phosphatase activity
HPC62_RS13765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HPC62_RS13770	COG0494	nUDIX hydrolase
HPC62_RS13810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPC62_RS13825	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HPC62_RS13835	COG0640	Transcriptional regulator
HPC62_RS13845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HPC62_RS13875	COG0022	dehydrogenase e1 component
HPC62_RS13875	COG0508	dehydrogenase complex catalyzes the overall conversion of
HPC62_RS13885	COG3447	MASE1 domain protein
HPC62_RS13885	COG5001	Diguanylate cyclase
HPC62_RS13885	COG5002	protein histidine kinase activity
HPC62_RS13895	COG1672	PFAM Archaeal ATPase
HPC62_RS13895	COG2319	Wd-40 repeat
HPC62_RS13940	COG0436	Aminotransferase
HPC62_RS13980	COG0589	response to stress
HPC62_RS13995	COG0716	FMN binding
HPC62_RS14000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HPC62_RS14005	COG0803	Belongs to the bacterial solute-binding protein 9 family
HPC62_RS14005	COG3443	Belongs to the bacterial solute-binding protein 9 family
HPC62_RS14060	COG1649	PFAM Uncharacterised BCR, COG1649
HPC62_RS14075	COG0673	inositol 2-dehydrogenase activity
HPC62_RS14080	COG0745	RESPONSE REGULATOR receiver
HPC62_RS14095	COG0714	Associated with various cellular activities
HPC62_RS14115	COG3118	belongs to the thioredoxin family
HPC62_RS14120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPC62_RS14140	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPC62_RS14145	COG2239	Acts as a magnesium transporter
HPC62_RS14150	COG1234	tRNA 3'-trailer cleavage
HPC62_RS14155	COG1268	BioY protein
HPC62_RS14160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPC62_RS14165	COG1773	rubredoxin
HPC62_RS14170	COG4447	cellulose binding
HPC62_RS14210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HPC62_RS14245	COG5002	protein histidine kinase activity
HPC62_RS14255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HPC62_RS14260	COG3659	wide pore channel activity
HPC62_RS14265	COG0784	Response regulator, receiver
HPC62_RS14270	COG2205	protein histidine kinase activity
HPC62_RS14275	COG0590	tRNA wobble adenosine to inosine editing
HPC62_RS14280	COG0492	ferredoxin-NADP+ reductase activity
HPC62_RS14315	COG1836	PFAM Integral membrane protein DUF92
HPC62_RS14320	COG5002	protein histidine kinase activity
HPC62_RS14345	COG3128	pkhd-type hydroxylase
HPC62_RS14365	COG4249	Peptidase C14 caspase catalytic subunit p20
HPC62_RS14365	COG2319	Wd-40 repeat
HPC62_RS14370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPC62_RS14375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPC62_RS14420	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS14430	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPC62_RS14450	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS14455	COG1895	HEPN domain
HPC62_RS14460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HPC62_RS14480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPC62_RS14525	COG0113	porphobilinogen synthase activity
HPC62_RS14535	COG4221	oxidoreductase activity
HPC62_RS14540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HPC62_RS14565	COG3848	Pyruvate phosphate dikinase
HPC62_RS14565	COG0574	Belongs to the PEP-utilizing enzyme family
HPC62_RS14585	COG4636	protein conserved in cyanobacteria
HPC62_RS14605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HPC62_RS14610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPC62_RS14620	COG1846	Transcriptional regulator
HPC62_RS14645	COG1333	cytochrome c biogenesis protein
HPC62_RS14650	COG0157	Belongs to the NadC ModD family
HPC62_RS14690	COG0673	inositol 2-dehydrogenase activity
HPC62_RS14710	COG1410	methionine synthase
HPC62_RS14710	COG0646	methionine synthase
HPC62_RS14725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS14730	COG0318	PFAM AMP-dependent synthetase and ligase
HPC62_RS14735	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HPC62_RS14740	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPC62_RS14740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS14745	COG3639	organic phosphonate transmembrane transporter activity
HPC62_RS14750	COG4251	negative regulation of phosphorylation
HPC62_RS14760	COG1070	Carbohydrate kinase
HPC62_RS14780	COG4221	oxidoreductase activity
HPC62_RS14785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPC62_RS14785	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HPC62_RS14800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPC62_RS14805	COG0174	glutamine synthetase
HPC62_RS14810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPC62_RS14840	COG0629	single-stranded DNA binding
HPC62_RS14855	COG3266	domain, Protein
HPC62_RS14855	COG2911	Protein conserved in bacteria
HPC62_RS14855	COG1361	Conserved repeat domain
HPC62_RS14865	COG4636	protein conserved in cyanobacteria
HPC62_RS14875	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HPC62_RS14880	COG2066	Belongs to the glutaminase family
HPC62_RS14915	COG2175	clavaminate synthase activity
HPC62_RS14925	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HPC62_RS14930	COG0778	Nitroreductase
HPC62_RS14940	COG0616	signal peptide processing
HPC62_RS14975	COG2268	Band 7 protein
HPC62_RS15040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPC62_RS15060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_RS15075	COG0488	(ABC) transporter
HPC62_RS15080	COG0772	Belongs to the SEDS family
HPC62_RS15100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPC62_RS15105	COG1122	ATPase activity
HPC62_RS15140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HPC62_RS15145	COG0133	tryptophan synthase activity
HPC62_RS15155	COG0023	Translation Initiation Factor
HPC62_RS15165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HPC62_RS15175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HPC62_RS15180	COG1191	sigma factor activity
HPC62_RS15195	COG3852	Histidine kinase
HPC62_RS15260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HPC62_RS15270	COG0577	efflux transmembrane transporter activity
HPC62_RS15310	COG1468	defense response to virus
HPC62_RS15310	COG1518	maintenance of DNA repeat elements
HPC62_RS15375	COG5002	protein histidine kinase activity
HPC62_RS15410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HPC62_RS15440	COG1132	(ABC) transporter
HPC62_RS15450	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS15450	COG0515	serine threonine protein kinase
HPC62_RS15490	COG2267	carboxylic ester hydrolase activity
HPC62_RS15500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPC62_RS15515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPC62_RS15525	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS15525	COG0515	serine threonine protein kinase
HPC62_RS15535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPC62_RS15555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPC62_RS15585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HPC62_RS15590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HPC62_RS15595	COG1845	cytochrome c oxidase, subunit III
HPC62_RS15610	COG2197	response regulator
HPC62_RS15615	COG4585	Histidine kinase
HPC62_RS15620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HPC62_RS15640	COG0033	Phosphoglucomutase
HPC62_RS15645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPC62_RS15650	COG0588	phosphoglycerate mutase activity
HPC62_RS15655	COG0469	pyruvate kinase activity
HPC62_RS15665	COG0824	Thioesterase
HPC62_RS15670	COG1799	cell septum assembly
HPC62_RS15685	COG4191	Histidine kinase
HPC62_RS15700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPC62_RS15705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPC62_RS15720	COG0336	Belongs to the RNA methyltransferase TrmD family
HPC62_RS15725	COG4242	Belongs to the peptidase S51 family
HPC62_RS15730	COG0189	ligase activity
HPC62_RS15730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPC62_RS15750	COG5002	protein histidine kinase activity
HPC62_RS15765	COG0300	oxidoreductase activity
HPC62_RS15765	COG3000	fatty acid hydroxylase
HPC62_RS15775	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS15780	COG0573	inorganic phosphate transmembrane transporter activity
HPC62_RS15785	COG0581	inorganic phosphate transmembrane transporter activity
HPC62_RS15790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HPC62_RS15815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPC62_RS15820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPC62_RS15820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPC62_RS15845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPC62_RS15865	COG5001	Diguanylate cyclase
HPC62_RS15870	COG0442	prolyl-tRNA aminoacylation
HPC62_RS15895	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HPC62_RS15895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HPC62_RS15900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPC62_RS15900	COG2205	protein histidine kinase activity
HPC62_RS15905	COG2197	response regulator
HPC62_RS15920	COG0589	response to stress
HPC62_RS15920	COG0475	glutathione-regulated potassium exporter activity
HPC62_RS15925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPC62_RS15930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPC62_RS15940	COG0514	ATP-dependent DNA helicase (RecQ)
HPC62_RS15955	COG1741	Belongs to the pirin family
HPC62_RS15965	COG1733	regulation of RNA biosynthetic process
HPC62_RS15990	COG3629	intracellular signal transduction
HPC62_RS15990	COG3903	Transcriptional regulator
HPC62_RS16000	COG4636	protein conserved in cyanobacteria
HPC62_RS16005	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HPC62_RS16025	COG1131	(ABC) transporter
HPC62_RS16030	COG3604	Transcriptional regulator
HPC62_RS16035	COG0640	Transcriptional regulator
HPC62_RS16070	COG1012	belongs to the aldehyde dehydrogenase family
HPC62_RS16075	COG0174	glutamine synthetase
HPC62_RS16090	COG1201	RNA secondary structure unwinding
HPC62_RS16205	COG1090	epimerase
HPC62_RS16220	COG1126	abc transporter atp-binding protein
HPC62_RS16230	COG0612	Peptidase, M16
HPC62_RS16240	COG2204	response regulator
HPC62_RS16245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HPC62_RS16275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPC62_RS16290	COG0515	serine threonine protein kinase
HPC62_RS16290	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS16295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPC62_RS16310	COG0358	DNA primase activity
HPC62_RS16335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPC62_RS16340	COG1230	cation diffusion facilitator family transporter
HPC62_RS16365	COG1653	transport
HPC62_RS16390	COG0475	glutathione-regulated potassium exporter activity
HPC62_RS16415	COG0489	protein tyrosine kinase activity
HPC62_RS16420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPC62_RS16465	COG0668	transmembrane transport
HPC62_RS16510	COG0628	permease
HPC62_RS16515	COG0398	Pfam SNARE associated Golgi protein
HPC62_RS16520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPC62_RS16525	COG0398	Pfam SNARE associated Golgi protein
HPC62_RS16565	COG0071	Belongs to the small heat shock protein (HSP20) family
HPC62_RS16575	COG0149	triose-phosphate isomerase activity
HPC62_RS16610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPC62_RS16615	COG0583	DNA-binding transcription factor activity
HPC62_RS16620	COG0697	spore germination
HPC62_RS16625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPC62_RS16655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPC62_RS16720	COG0697	spore germination
HPC62_RS16730	COG0671	phosphoesterase, PA-phosphatase related
HPC62_RS16740	COG0745	RESPONSE REGULATOR receiver
HPC62_RS16770	COG0832	Belongs to the urease beta subunit family
HPC62_RS16775	COG0831	urea catabolic process
HPC62_RS16780	COG0037	tRNA processing
HPC62_RS16790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HPC62_RS16800	COG0312	modulator of DNA gyrase
HPC62_RS16805	COG2226	methyltransferase
HPC62_RS16810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HPC62_RS16845	COG3385	transposase activity
HPC62_RS16860	COG4172	Belongs to the ABC transporter superfamily
HPC62_RS16865	COG0740	serine-type endopeptidase activity
HPC62_RS16870	COG5322	oxidoreductase activity
HPC62_RS16880	COG0006	proline dipeptidase activity
HPC62_RS16895	COG3854	ATPases associated with a variety of cellular activities
HPC62_RS16910	COG0457	Tetratricopeptide repeat
HPC62_RS16915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPC62_RS16920	COG0328	RNA-DNA hybrid ribonuclease activity
HPC62_RS16925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HPC62_RS16945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPC62_RS16950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPC62_RS16960	COG2082	Precorrin-8x methylmutase
HPC62_RS17030	COG5002	protein histidine kinase activity
HPC62_RS17035	COG0724	RNA recognition motif
HPC62_RS17050	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS17055	COG0784	Response regulator, receiver
HPC62_RS17070	COG2203	Gaf domain
HPC62_RS17070	COG0840	transmembrane signaling receptor activity
HPC62_RS17075	COG0643	Histidine kinase
HPC62_RS17075	COG0784	Response regulator, receiver
HPC62_RS17075	COG2198	Histidine kinase
HPC62_RS17090	COG2738	Putative neutral zinc metallopeptidase
HPC62_RS17110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPC62_RS17115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HPC62_RS17130	COG0395	ABC-type sugar transport system, permease component
HPC62_RS17160	COG0504	CTP synthase activity
HPC62_RS17185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPC62_RS17190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HPC62_RS17195	COG1136	(ABC) transporter
HPC62_RS17200	COG1136	(ABC) transporter
HPC62_RS17200	COG0577	efflux transmembrane transporter activity
HPC62_RS17205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPC62_RS17220	COG0154	amidase activity
HPC62_RS17230	COG3688	RNA-binding protein containing a PIN domain
HPC62_RS17240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPC62_RS17250	COG3118	belongs to the thioredoxin family
HPC62_RS17255	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS17260	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HPC62_RS17265	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HPC62_RS17300	COG0577	efflux transmembrane transporter activity
HPC62_RS17300	COG1136	(ABC) transporter
HPC62_RS17305	COG1252	NADH dehydrogenase
HPC62_RS17310	COG1011	Hydrolase
HPC62_RS17325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HPC62_RS17335	COG1597	lipid kinase activity
HPC62_RS17335	COG1803	Methylglyoxal synthase
HPC62_RS17340	COG0693	protein deglycase activity
HPC62_RS17355	COG1181	Belongs to the D-alanine--D-alanine ligase family
HPC62_RS17365	COG0557	exoribonuclease II activity
HPC62_RS17375	COG0704	Plays a role in the regulation of phosphate uptake
HPC62_RS17395	COG4191	Histidine kinase
HPC62_RS17395	COG0784	Response regulator, receiver
HPC62_RS17410	COG1840	ABC-type Fe3 transport system, periplasmic component
HPC62_RS17415	COG3128	pkhd-type hydroxylase
HPC62_RS17420	COG3487	Iron-regulated protein
HPC62_RS17430	COG2197	response regulator
HPC62_RS17495	COG0779	Required for maturation of 30S ribosomal subunits
HPC62_RS17500	COG0195	Participates in both transcription termination and antitermination
HPC62_RS17505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPC62_RS17525	COG0419	ATPase involved in DNA repair
HPC62_RS17530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPC62_RS17540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPC62_RS17560	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPC62_RS17575	COG1672	PFAM Archaeal ATPase
HPC62_RS17575	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HPC62_RS17585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPC62_RS17600	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS17605	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS17630	COG1546	Belongs to the CinA family
HPC62_RS17630	COG1058	Belongs to the CinA family
HPC62_RS17635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPC62_RS17655	COG2814	Major facilitator Superfamily
HPC62_RS17690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HPC62_RS17715	COG0297	glycogen (starch) synthase activity
HPC62_RS17720	COG0501	Belongs to the peptidase M48B family
HPC62_RS17735	COG2361	Protein of unknown function DUF86
HPC62_RS17745	COG0556	nucleotide-excision repair
HPC62_RS17750	COG0463	Glycosyl transferase, family 2
HPC62_RS17755	COG0628	permease
HPC62_RS17790	COG0247	lactate metabolic process
HPC62_RS17795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPC62_RS17800	COG4935	Belongs to the peptidase S8 family
HPC62_RS17800	COG1404	Belongs to the peptidase S8 family
HPC62_RS17810	COG1132	(ABC) transporter
HPC62_RS17820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPC62_RS17840	COG1160	GTP binding
HPC62_RS17865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HPC62_RS17875	COG0830	nickel cation binding
HPC62_RS17900	COG0457	Tetratricopeptide repeat
HPC62_RS17900	COG0463	Glycosyl transferase, family 2
HPC62_RS17910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HPC62_RS17915	COG0594	ribonuclease P activity
HPC62_RS17925	COG0706	membrane insertase activity
HPC62_RS17940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPC62_RS17965	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS17970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPC62_RS17980	COG1032	radical SAM domain protein
HPC62_RS18010	COG0702	epimerase
HPC62_RS18025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HPC62_RS18030	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPC62_RS18035	COG1178	ABC-type Fe3 transport system permease component
HPC62_RS18040	COG3842	ATPase activity
HPC62_RS18045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPC62_RS18050	COG0010	Belongs to the arginase family
HPC62_RS18065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPC62_RS18085	COG0006	proline dipeptidase activity
HPC62_RS18110	COG0469	pyruvate kinase activity
HPC62_RS18115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPC62_RS18120	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPC62_RS18125	COG4999	Histidine kinase
HPC62_RS18125	COG3850	Histidine kinase
HPC62_RS18125	COG3437	response regulator, receiver
HPC62_RS18125	COG2205	protein histidine kinase activity
HPC62_RS18130	COG0784	Response regulator, receiver
HPC62_RS18135	COG4251	negative regulation of phosphorylation
HPC62_RS18140	COG2197	response regulator
HPC62_RS18145	COG0412	Dienelactone hydrolase
HPC62_RS18155	COG1185	polyribonucleotide nucleotidyltransferase activity
HPC62_RS18170	COG0539	negative regulation of cytoplasmic translation
HPC62_RS18175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPC62_RS18200	COG0540	Belongs to the ATCase OTCase family
HPC62_RS18205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPC62_RS18210	COG0366	Alpha amylase catalytic
HPC62_RS18225	COG2816	NAD+ diphosphatase activity
HPC62_RS18230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPC62_RS18240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPC62_RS18255	COG2962	Rard protein
HPC62_RS18275	COG4251	negative regulation of phosphorylation
HPC62_RS18275	COG2203	Gaf domain
HPC62_RS18275	COG5001	Diguanylate cyclase
HPC62_RS18275	COG3706	GGDEF domain
HPC62_RS18280	COG0784	Response regulator, receiver
HPC62_RS18285	COG4251	negative regulation of phosphorylation
HPC62_RS18290	COG0741	lytic transglycosylase activity
HPC62_RS18295	COG3852	Histidine kinase
HPC62_RS18315	COG0454	-acetyltransferase
HPC62_RS18350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HPC62_RS18360	COG0058	SHG alpha-glucan phosphorylase activity
HPC62_RS18390	COG0644	oxidoreductase
HPC62_RS18400	COG1063	alcohol dehydrogenase
HPC62_RS18405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPC62_RS18420	COG1253	flavin adenine dinucleotide binding
HPC62_RS18430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPC62_RS18435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HPC62_RS18440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS18450	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HPC62_RS18455	COG0067	glutamate synthase
HPC62_RS18455	COG0069	glutamate synthase activity
HPC62_RS18455	COG0070	glutamate synthase
HPC62_RS18460	COG0493	'glutamate synthase
HPC62_RS18470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPC62_RS18475	COG0668	transmembrane transport
HPC62_RS18495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPC62_RS18525	COG2010	Cytochrome c
HPC62_RS18540	COG0251	oxidation-reduction process
HPC62_RS18550	COG1194	a g-specific adenine glycosylase
HPC62_RS18560	COG5002	protein histidine kinase activity
HPC62_RS18565	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS18570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPC62_RS18575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPC62_RS18585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPC62_RS18615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPC62_RS18630	COG1253	flavin adenine dinucleotide binding
HPC62_RS18635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPC62_RS18645	COG0501	Belongs to the peptidase M48B family
HPC62_RS18665	COG0745	RESPONSE REGULATOR receiver
HPC62_RS18675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPC62_RS18680	COG2351	hydroxyisourate hydrolase activity
HPC62_RS18685	COG0574	Belongs to the PEP-utilizing enzyme family
HPC62_RS18685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPC62_RS18690	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HPC62_RS18695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPC62_RS18710	COG1012	belongs to the aldehyde dehydrogenase family
HPC62_RS18710	COG1454	alcohol dehydrogenase
HPC62_RS18720	COG1733	regulation of RNA biosynthetic process
HPC62_RS18725	COG0672	)-iron permease
HPC62_RS18745	COG0436	Aminotransferase
HPC62_RS18750	COG0371	Dehydrogenase
HPC62_RS18770	COG2308	Evidence 4 Homologs of previously reported genes of
HPC62_RS18785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPC62_RS18790	COG1970	mechanosensitive ion channel activity
HPC62_RS18795	COG0415	Belongs to the DNA photolyase family
HPC62_RS18830	COG0783	Belongs to the Dps family
HPC62_RS18835	COG3781	membrane
HPC62_RS18840	COG0583	DNA-binding transcription factor activity
HPC62_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HPC62_RS18870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HPC62_RS18870	COG1116	anion transmembrane transporter activity
HPC62_RS18875	COG1116	anion transmembrane transporter activity
HPC62_RS18880	COG0243	molybdopterin cofactor binding
HPC62_RS18905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPC62_RS18910	COG0501	Belongs to the peptidase M48B family
HPC62_RS18920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HPC62_RS18950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS18955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HPC62_RS18960	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HPC62_RS18965	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HPC62_RS18970	COG4451	ribulose bisphosphate carboxylase, small
HPC62_RS18970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HPC62_RS18980	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HPC62_RS18995	COG0631	protein serine/threonine phosphatase activity
HPC62_RS19000	COG1187	pseudouridine synthase activity
HPC62_RS19025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HPC62_RS19035	COG0038	chloride channel
HPC62_RS19050	COG3385	transposase activity
HPC62_RS19075	COG0501	Belongs to the peptidase M48B family
HPC62_RS19080	COG2954	triphosphatase activity
HPC62_RS19105	COG4948	Mandelate Racemase Muconate Lactonizing
HPC62_RS19110	COG0482	sulfurtransferase activity
HPC62_RS19115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HPC62_RS19120	COG0859	PFAM glycosyl transferase family 9
HPC62_RS19125	COG0625	glutathione transferase activity
HPC62_RS19130	COG0789	Transcriptional regulator
HPC62_RS19190	COG0668	transmembrane transport
HPC62_RS19210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HPC62_RS19225	COG0174	glutamine synthetase
HPC62_RS19250	COG0352	thiamine-phosphate diphosphorylase activity
HPC62_RS19260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPC62_RS19295	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HPC62_RS19305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPC62_RS19350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HPC62_RS19355	COG0601	transmembrane transport
HPC62_RS19365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPC62_RS19380	COG0793	Belongs to the peptidase S41A family
HPC62_RS19385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HPC62_RS19400	COG0386	Belongs to the glutathione peroxidase family
HPC62_RS19405	COG0528	UMP kinase activity
HPC62_RS19410	COG0233	cytoplasmic translational termination
HPC62_RS19415	COG0492	ferredoxin-NADP+ reductase activity
HPC62_RS19420	COG5002	protein histidine kinase activity
HPC62_RS19425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HPC62_RS19430	COG2154	pterin-4-alpha-carbinolamine dehydratase
HPC62_RS19440	COG1176	ABC-type spermidine putrescine transport system, permease component I
HPC62_RS19450	COG1116	anion transmembrane transporter activity
HPC62_RS19455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HPC62_RS19470	COG1615	UPF0182 protein
HPC62_RS19485	COG4968	Prepilin-type N-terminal cleavage methylation domain
HPC62_RS19490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HPC62_RS19505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPC62_RS19515	COG1492	cobalamin metabolic process
HPC62_RS19545	COG0582	viral genome integration into host DNA
HPC62_RS19550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HPC62_RS19560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPC62_RS19590	COG3224	Antibiotic biosynthesis monooxygenase
HPC62_RS19600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPC62_RS19610	COG1316	TRANSCRIPTIONal
HPC62_RS19630	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HPC62_RS19635	COG0058	SHG alpha-glucan phosphorylase activity
HPC62_RS19665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HPC62_RS19680	COG1136	(ABC) transporter
HPC62_RS19685	COG2208	phosphoserine phosphatase activity
HPC62_RS19700	COG0165	Argininosuccinate lyase
HPC62_RS19710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HPC62_RS19715	COG2045	Belongs to the ComB family
HPC62_RS19720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPC62_RS19725	COG0575	Belongs to the CDS family
HPC62_RS19735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPC62_RS19740	COG4399	Belongs to the UPF0754 family
HPC62_RS19750	COG3937	granule-associated protein
HPC62_RS19780	COG0625	glutathione transferase activity
HPC62_RS19790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HPC62_RS19810	COG0517	IMP dehydrogenase activity
HPC62_RS19810	COG1994	Peptidase M50
HPC62_RS19815	COG0546	phosphoglycolate phosphatase activity
HPC62_RS19820	COG1793	dna ligase
HPC62_RS19825	COG3852	Histidine kinase
HPC62_RS19830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HPC62_RS19835	COG1028	Short-chain dehydrogenase reductase Sdr
HPC62_RS19845	COG0051	transcription antitermination factor activity, RNA binding
HPC62_RS19850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPC62_RS19855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPC62_RS19860	COG0049	tRNA binding
HPC62_RS19865	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPC62_RS19870	COG0316	Belongs to the HesB IscA family
HPC62_RS19875	COG0662	Cupin 2, conserved barrel domain protein
HPC62_RS19875	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HPC62_RS19910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPC62_RS19925	COG1192	Involved in chromosome partitioning
HPC62_RS19950	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HPC62_RS19955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HPC62_RS19980	COG0783	Belongs to the Dps family
HPC62_RS19995	COG1420	regulation of RNA biosynthetic process
HPC62_RS20005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HPC62_RS20010	COG1446	asparaginase
HPC62_RS20035	COG1040	competence protein
HPC62_RS20040	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPC62_RS20045	COG4968	Prepilin-type N-terminal cleavage methylation domain
HPC62_RS20065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPC62_RS20095	COG0259	pyridoxamine-phosphate oxidase activity
HPC62_RS20105	COG5002	protein histidine kinase activity
HPC62_RS20110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPC62_RS20130	COG0542	response to heat
HPC62_RS20145	COG0745	RESPONSE REGULATOR receiver
HPC62_RS20150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPC62_RS20170	COG2203	Gaf domain
HPC62_RS20170	COG4251	negative regulation of phosphorylation
HPC62_RS20170	COG5001	Diguanylate cyclase
HPC62_RS20170	COG3706	GGDEF domain
HPC62_RS20175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HPC62_RS20180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HPC62_RS20220	COG0024	Methionine aminopeptidase
HPC62_RS20265	COG1666	GTP binding
HPC62_RS20285	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS20295	COG0583	DNA-binding transcription factor activity
HPC62_RS20315	COG0489	protein tyrosine kinase activity
HPC62_RS20345	COG1091	dTDP-4-dehydrorhamnose reductase activity
HPC62_RS20355	COG1088	dTDP-glucose 4,6-dehydratase activity
HPC62_RS20375	COG1132	(ABC) transporter
HPC62_RS20380	COG0668	transmembrane transport
HPC62_RS20385	COG0653	protein targeting
HPC62_RS20410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HPC62_RS20430	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HPC62_RS20445	COG2205	protein histidine kinase activity
HPC62_RS20490	COG1899	peptidyl-lysine modification to peptidyl-hypusine
HPC62_RS20505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPC62_RS20510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPC62_RS20515	COG0484	heat shock protein binding
HPC62_RS20530	COG0519	Catalyzes the synthesis of GMP from XMP
HPC62_RS20550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HPC62_RS20550	COG2022	thiamine diphosphate biosynthetic process
HPC62_RS20590	COG1216	Glycosyl transferase, family 2
HPC62_RS20595	COG2814	Major facilitator Superfamily
HPC62_RS20620	COG1192	Involved in chromosome partitioning
HPC62_RS20630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HPC62_RS20660	COG0800	Aldolase
HPC62_RS20675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPC62_RS20695	COG0443	Heat shock 70 kDa protein
HPC62_RS20705	COG1741	Belongs to the pirin family
HPC62_RS20765	COG5002	protein histidine kinase activity
HPC62_RS20820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HPC62_RS20825	COG2267	carboxylic ester hydrolase activity
HPC62_RS20835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HPC62_RS20845	COG0306	phosphate transporter
HPC62_RS20860	COG0572	uridine kinase
HPC62_RS20920	COG0571	ribonuclease III activity
HPC62_RS20930	COG3437	response regulator, receiver
HPC62_RS20935	COG3265	gluconokinase activity
HPC62_RS20945	COG1522	sequence-specific DNA binding
HPC62_RS20955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HPC62_RS20960	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPC62_RS20970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HPC62_RS20975	COG0025	NhaP-type Na H and K H
HPC62_RS20985	COG1070	Carbohydrate kinase
HPC62_RS20995	COG2890	protein-(glutamine-N5) methyltransferase activity
HPC62_RS21005	COG0009	L-threonylcarbamoyladenylate synthase
HPC62_RS21015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPC62_RS21015	COG0237	dephospho-CoA kinase activity
HPC62_RS21030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPC62_RS21030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPC62_RS21040	COG2226	methyltransferase
HPC62_RS21045	COG0463	Glycosyl transferase, family 2
HPC62_RS21060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HPC62_RS21065	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HPC62_RS21070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HPC62_RS21090	COG3437	response regulator, receiver
HPC62_RS21120	COG1672	PFAM Archaeal ATPase
HPC62_RS21125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HPC62_RS21145	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS21150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPC62_RS21155	COG4191	Histidine kinase
HPC62_RS21210	COG1253	flavin adenine dinucleotide binding
HPC62_RS21215	COG1725	Transcriptional regulator
HPC62_RS21235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPC62_RS21250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPC62_RS21250	COG3266	domain, Protein
HPC62_RS21260	COG0497	DNA recombination
HPC62_RS21275	COG0616	signal peptide processing
HPC62_RS21280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPC62_RS21295	COG1473	amidohydrolase
HPC62_RS21300	COG0330	HflC and HflK could
HPC62_RS21305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPC62_RS21310	COG0254	rRNA binding
HPC62_RS21315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HPC62_RS21320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPC62_RS21325	COG0101	tRNA pseudouridine synthase activity
HPC62_RS21330	COG0203	ribosomal protein L17
HPC62_RS21335	COG0202	RNA polymerase activity
HPC62_RS21340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPC62_RS21345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPC62_RS21350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HPC62_RS21355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPC62_RS21360	COG0563	adenylate kinase activity
HPC62_RS21365	COG0201	protein transport
HPC62_RS21370	COG0200	Binds to the 23S rRNA
HPC62_RS21375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPC62_RS21380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPC62_RS21385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPC62_RS21390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPC62_RS21395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPC62_RS21400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPC62_RS21405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPC62_RS21410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPC62_RS21415	COG0255	Belongs to the universal ribosomal protein uL29 family
HPC62_RS21420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPC62_RS21425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPC62_RS21430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPC62_RS21435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPC62_RS21440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPC62_RS21445	COG0089	rRNA binding
HPC62_RS21450	COG0088	Forms part of the polypeptide exit tunnel
HPC62_RS21455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPC62_RS21465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPC62_RS21475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HPC62_RS21525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HPC62_RS21530	COG1121	(ABC) transporter
HPC62_RS21535	COG0803	Belongs to the bacterial solute-binding protein 9 family
HPC62_RS21540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HPC62_RS21575	COG3659	wide pore channel activity
HPC62_RS21590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPC62_RS21595	COG5002	protein histidine kinase activity
HPC62_RS21600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HPC62_RS21605	COG0572	uridine kinase
HPC62_RS21610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HPC62_RS21640	COG3850	Histidine kinase
HPC62_RS21640	COG5002	protein histidine kinase activity
HPC62_RS21670	COG0351	phosphomethylpyrimidine kinase
HPC62_RS21685	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPC62_RS21700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HPC62_RS21705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPC62_RS21710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HPC62_RS21715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HPC62_RS21725	COG5002	protein histidine kinase activity
HPC62_RS21730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPC62_RS21740	COG2010	Cytochrome c
HPC62_RS21750	COG0297	glycogen (starch) synthase activity
HPC62_RS21765	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS21765	COG0297	glycogen (starch) synthase activity
HPC62_RS21780	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS21790	COG0393	Putative heavy-metal-binding
HPC62_RS21800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS21805	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPC62_RS21810	COG0484	heat shock protein binding
HPC62_RS21815	COG0483	inositol monophosphate 1-phosphatase activity
HPC62_RS21820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HPC62_RS21830	COG0697	spore germination
HPC62_RS21840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPC62_RS21880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPC62_RS21905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HPC62_RS21915	COG1193	negative regulation of DNA recombination
HPC62_RS21955	COG0586	Pfam SNARE associated Golgi protein
HPC62_RS21975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPC62_RS21975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPC62_RS22025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HPC62_RS22035	COG5001	Diguanylate cyclase
HPC62_RS22040	COG0314	molybdopterin synthase activity
HPC62_RS22045	COG0737	Belongs to the 5'-nucleotidase family
HPC62_RS22050	COG0793	Belongs to the peptidase S41A family
HPC62_RS22055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HPC62_RS22060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPC62_RS22065	COG0735	belongs to the Fur family
HPC62_RS22080	COG0762	integral membrane protein
HPC62_RS22090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPC62_RS22100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPC62_RS22130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HPC62_RS22140	COG0747	negative chemotaxis
HPC62_RS22150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HPC62_RS22160	COG2062	phosphohistidine phosphatase, SixA
HPC62_RS22170	COG1027	Aspartate ammonia-lyase
HPC62_RS22190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPC62_RS22215	COG1022	Amp-dependent synthetase and ligase
HPC62_RS22225	COG0508	dehydrogenase complex catalyzes the overall conversion of
HPC62_RS22245	COG1316	TRANSCRIPTIONal
HPC62_RS22250	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS22270	COG1722	exodeoxyribonuclease VII activity
HPC62_RS22280	COG1570	exodeoxyribonuclease VII activity
HPC62_RS22285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPC62_RS22305	COG1959	2 iron, 2 sulfur cluster binding
HPC62_RS22310	COG2119	membrane
HPC62_RS22330	COG1357	PFAM Pentapeptide repeats (8 copies)
HPC62_RS22330	COG0515	serine threonine protein kinase
HPC62_RS22340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HPC62_RS22345	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS22375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPC62_RS22385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPC62_RS22390	COG0052	Belongs to the universal ribosomal protein uS2 family
HPC62_RS22395	COG0434	BtpA family
HPC62_RS22400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPC62_RS22405	COG0513	Belongs to the DEAD box helicase family
HPC62_RS22410	COG3706	GGDEF domain
HPC62_RS22410	COG2203	Gaf domain
HPC62_RS22410	COG5001	Diguanylate cyclase
HPC62_RS22410	COG4251	negative regulation of phosphorylation
HPC62_RS22420	COG3118	belongs to the thioredoxin family
HPC62_RS22425	COG0436	Aminotransferase
HPC62_RS22435	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS22440	COG1122	ATPase activity
HPC62_RS22455	COG2154	pterin-4-alpha-carbinolamine dehydratase
HPC62_RS22460	COG3659	wide pore channel activity
HPC62_RS22465	COG1959	2 iron, 2 sulfur cluster binding
HPC62_RS22470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HPC62_RS22475	COG0484	heat shock protein binding
HPC62_RS22480	COG1160	GTP binding
HPC62_RS22485	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPC62_RS22490	COG0736	holo-[acyl-carrier-protein] synthase activity
HPC62_RS22500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPC62_RS22505	COG1304	FMN binding
HPC62_RS22510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPC62_RS22515	COG0857	belongs to the CobB CobQ family
HPC62_RS22525	COG2252	PERMEase
HPC62_RS22530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HPC62_RS22535	COG0697	spore germination
HPC62_RS22570	COG1177	transmembrane transport
HPC62_RS22585	COG3842	ATPase activity
HPC62_RS22605	COG0463	Glycosyl transferase, family 2
HPC62_RS22605	COG1216	Glycosyl transferase, family 2
HPC62_RS22610	COG1177	transmembrane transport
HPC62_RS22615	COG3842	ATPase activity
HPC62_RS22620	COG5002	protein histidine kinase activity
HPC62_RS22635	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS22645	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS22665	COG0561	phosphatase activity
HPC62_RS22675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPC62_RS22690	COG0012	GTP binding
HPC62_RS22715	COG1215	transferase activity, transferring glycosyl groups
HPC62_RS22720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HPC62_RS22750	COG0322	excinuclease ABC activity
HPC62_RS22760	COG0515	serine threonine protein kinase
HPC62_RS22765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPC62_RS22770	COG0439	Biotin carboxylase
HPC62_RS22780	COG5398	heme oxygenase
HPC62_RS22790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HPC62_RS22800	COG1404	Belongs to the peptidase S8 family
HPC62_RS22800	COG4935	Belongs to the peptidase S8 family
HPC62_RS22810	COG0271	Belongs to the BolA IbaG family
HPC62_RS22815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HPC62_RS22835	COG0047	phosphoribosylformylglycinamidine synthase activity
HPC62_RS22840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPC62_RS22850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HPC62_RS22870	COG2217	Heavy metal translocating P-type atpase
HPC62_RS22875	COG0571	ribonuclease III activity
HPC62_RS22890	COG0004	ammonium transporteR
HPC62_RS22905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HPC62_RS22915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS22930	COG0515	serine threonine protein kinase
HPC62_RS23065	COG0297	glycogen (starch) synthase activity
HPC62_RS23065	COG0438	transferase activity, transferring glycosyl groups
HPC62_RS23115	COG0604	alcohol dehydrogenase
HPC62_RS23115	COG3321	synthase
HPC62_RS23140	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HPC62_RS23160	COG3179	chitinase
HPC62_RS23175	COG3063	Type IV pilus biogenesis stability protein PilW
HPC62_RS23235	COG0564	pseudouridine synthase activity
HPC62_RS23255	COG1376	ErfK ybiS ycfS ynhG family protein
HPC62_RS23325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HPC62_RS23335	COG1381	Involved in DNA repair and RecF pathway recombination
HPC62_RS23340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HPC62_RS23460	COG4172	Belongs to the ABC transporter superfamily
HPC62_RS23470	COG2022	thiamine diphosphate biosynthetic process
HPC62_RS23550	COG2340	Cysteine-rich secretory protein family
HPC62_RS23555	COG0784	Response regulator, receiver
HPC62_RS23555	COG5002	protein histidine kinase activity
HPC62_RS23605	COG0739	heme binding
HPC62_RS23645	COG0784	Response regulator, receiver
HPC62_RS23645	COG2205	protein histidine kinase activity
HPC62_RS23645	COG5002	protein histidine kinase activity
HPC62_RS23655	COG1397	ADP-ribosylglycohydrolase
HPC62_RS23730	COG0464	growth
HPC62_RS23760	COG1247	-acetyltransferase
HPC62_RS23765	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HPC62_RS23940	COG1028	Short-chain dehydrogenase reductase Sdr