locus-tag	class	description
HPC62_RS00130	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS00160	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HPC62_RS00165	ENOG4108JJA	ABC, transporter
HPC62_RS00175	ENOG4105BZ1	(ABC) transporter
HPC62_RS00250	ENOG4108R0D	protein with myosin-like
HPC62_RS00255	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HPC62_RS00260	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HPC62_RS00310	ENOG4105D1H	recombination factor protein RarA
HPC62_RS00340	ENOG41082AF	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HPC62_RS00365	ENOG4105VMP	Transcriptional regulator
HPC62_RS00390	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HPC62_RS00425	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HPC62_RS00445	ENOG41063JG	Transcriptional regulator
HPC62_RS00455	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPC62_RS00460	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HPC62_RS00470	ENOG4105C9B	Cysteine desulfurase
HPC62_RS00485	ENOG4105VFU	Rna-binding protein
HPC62_RS00490	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HPC62_RS00500	ENOG4105K6T	rare lipoprotein A
HPC62_RS00510	ENOG4105DZP	Membrane-associated zinc metalloprotease
HPC62_RS00515	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HPC62_RS00520	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_RS00535	ENOG4105C89	phosphohexose isomerase
HPC62_RS00555	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_RS00585	ENOG4107QI6	Cysteine desulfurase
HPC62_RS00590	ENOG4108HMN	Caspase domain
HPC62_RS00595	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPC62_RS00615	ENOG4106E83	A core subunit of photosystem II (PSII) (By similarity)
HPC62_RS00620	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HPC62_RS00625	ENOG4107YU2	histidine triad (hIT) protein
HPC62_RS00665	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HPC62_RS00685	ENOG4105ETX	regulatoR
HPC62_RS00705	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HPC62_RS00715	ENOG4105BZU	Histidine kinase
HPC62_RS00785	ENOG41066KU	photosystem I subunit X
HPC62_RS00805	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HPC62_RS00820	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HPC62_RS00825	ENOG41084GG	50S ribosomal protein L33
HPC62_RS00830	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HPC62_RS00835	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS00845	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPC62_RS00875	ENOG4105CS2	ec 3.2.1.21
HPC62_RS00880	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HPC62_RS00895	ENOG4108VX5	3-methyladenine DNA glycosylase
HPC62_RS00940	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HPC62_RS00970	ENOG4105BZU	Histidine kinase
HPC62_RS01015	ENOG4108SGF	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_RS01050	ENOG4108K7V	UPF0284 protein
HPC62_RS01070	ENOG4105BZM	domain protein
HPC62_RS01080	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPC62_RS01120	ENOG4105D7Z	glutathione synthase
HPC62_RS01135	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS01145	ENOG4107TTD	cytosine deaminase
HPC62_RS01155	ENOG4105C7K	acetolactate synthase
HPC62_RS01200	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HPC62_RS01205	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPC62_RS01215	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPC62_RS01230	ENOG4108W3Y	Transcriptional regulator, Crp Fnr family
HPC62_RS01235	ENOG41090A1	ferritin
HPC62_RS01245	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_RS01305	ENOG4105CSV	Glutaminase
HPC62_RS01310	ENOG4105D1F	ATP-binding protein
HPC62_RS01325	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPC62_RS01340	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HPC62_RS01345	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HPC62_RS01360	ENOG4105C12	Phosphoribosylglycinamide synthetase
HPC62_RS01375	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HPC62_RS01390	ENOG4105KRS	Proteinase inhibitor
HPC62_RS01405	ENOG4105DZC	cytosine deaminase
HPC62_RS01435	ENOG4105WN2	Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase (By similarity)
HPC62_RS01440	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HPC62_RS01455	ENOG4108YRB	methyltransferase
HPC62_RS01460	ENOG4107YFT	Nadph-dependent fmn reductase
HPC62_RS01465	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_RS01490	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HPC62_RS01500	ENOG4105CHH	sulfate transporter
HPC62_RS01505	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HPC62_RS01520	ENOG4107R73	Mate efflux family protein
HPC62_RS01545	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HPC62_RS01550	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HPC62_RS01555	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPC62_RS01565	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HPC62_RS01595	ENOG4105E4C	Lytic transglycosylase catalytic
HPC62_RS01600	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HPC62_RS01610	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPC62_RS01615	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPC62_RS01625	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPC62_RS01635	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS01645	ENOG4108IPT	Naphthoate synthase
HPC62_RS01660	ENOG4108J4B	Beta-lactamase
HPC62_RS01670	ENOG4105DR5	peptidase
HPC62_RS01715	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HPC62_RS01750	ENOG4105BZ1	(ABC) transporter
HPC62_RS01765	ENOG41060PQ	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
HPC62_RS01775	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HPC62_RS01790	ENOG4105BZU	Histidine kinase
HPC62_RS01800	ENOG4105BZU	Histidine kinase
HPC62_RS01820	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HPC62_RS01825	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPC62_RS01850	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HPC62_RS01860	ENOG410902K	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPC62_RS01870	ENOG4108HM4	ABC transporter
HPC62_RS01880	ENOG41080UQ	Transcriptional regulator
HPC62_RS01920	ENOG4105DGW	oligopeptidase A
HPC62_RS01940	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_RS01955	ENOG4107YJ4	chain length determinant protein
HPC62_RS01980	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HPC62_RS01995	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPC62_RS02045	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPC62_RS02070	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPC62_RS02185	ENOG41086B8	CoB-CoM heterodisulfide reductase
HPC62_RS02225	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
HPC62_RS02235	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS02285	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
HPC62_RS02290	ENOG4107T5V	SNARE associated Golgi
HPC62_RS02295	ENOG4107XR4	alpha beta
HPC62_RS02310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPC62_RS02315	ENOG4105CPC	Aldo Keto reductase
HPC62_RS02320	ENOG4105CAK	Cell division ATP-binding protein ftsE
HPC62_RS02350	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HPC62_RS02375	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
HPC62_RS02420	ENOG4105MN0	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HPC62_RS02425	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HPC62_RS02440	ENOG4105C5F	glutamine synthetase
HPC62_RS02445	ENOG4105BZU	Histidine kinase
HPC62_RS02465	ENOG4105E1F	short-chain dehydrogenase reductase
HPC62_RS02475	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HPC62_RS02520	ENOG4105C26	Dehydrogenase
HPC62_RS02540	ENOG4105C78	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_RS02565	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HPC62_RS02575	ENOG4107VAM	peptidase, m28
HPC62_RS02580	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HPC62_RS02590	ENOG4105BZU	Histidine kinase
HPC62_RS02595	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS02600	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HPC62_RS02605	ENOG4105CVN	desaturase
HPC62_RS02635	ENOG4105C3M	thioredoxin reductase
HPC62_RS02645	ENOG41082BG	Binds together with S18 to 16S ribosomal RNA (By similarity)
HPC62_RS02650	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPC62_RS02665	ENOG4105DRR	Transcriptional regulator, GntR family
HPC62_RS02670	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HPC62_RS02685	ENOG4105KC4	UPF0296 protein
HPC62_RS02705	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_RS02710	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HPC62_RS02720	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HPC62_RS02725	ENOG4105I4A	GCN5-related N-acetyltransferase
HPC62_RS02760	ENOG41080UQ	Transcriptional regulator
HPC62_RS02770	ENOG4105D64	Mechanosensitive ion channel
HPC62_RS02790	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPC62_RS02800	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HPC62_RS02815	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HPC62_RS02825	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPC62_RS02835	ENOG4105D3R	alkyl hydroperoxide reductase
HPC62_RS02845	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HPC62_RS02850	ENOG4107RNI	Glucose 6-phosphate dehydrogenase effector OpcA
HPC62_RS02860	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
HPC62_RS02870	ENOG4108TCG	allophycocyanin beta subunit
HPC62_RS02880	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS02900	ENOG4105W2E	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth (By similarity)
HPC62_RS02905	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HPC62_RS02920	ENOG4105CTK	cobaltochelatase, cobn subunit
HPC62_RS02930	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HPC62_RS02935	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPC62_RS02940	ENOG4108MAQ	allophycocyanin alpha
HPC62_RS02950	ENOG4105W5K	Rod linker protein, associated with allophycocyanin. Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer (By similarity)
HPC62_RS03030	ENOG4106WTF	Glycosyl transferase, family 2
HPC62_RS03040	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HPC62_RS03055	ENOG4105PGM	cation diffusion facilitator family transporter
HPC62_RS03065	ENOG4105VN1	Heat shock protein
HPC62_RS03070	ENOG4105C9X	ppx gppa phosphatase
HPC62_RS03080	ENOG4106HWW	Acyltransferase family
HPC62_RS03090	ENOG4105CAS	nag kinase
HPC62_RS03105	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HPC62_RS03120	ENOG4105E67	Catalyzes the four-electron reduction of biliverdin IX- alpha (2-electron reduction at both the A and D rings)
HPC62_RS03135	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HPC62_RS03145	ENOG4107RIQ	Sulfate adenylate transferase
HPC62_RS03155	ENOG4107FCW	Abortive infection protein
HPC62_RS03180	ENOG4105D6V	phycocyanin beta subunit
HPC62_RS03195	ENOG4108MZQ	phycobilisome linker polypeptide
HPC62_RS03200	ENOG4106DMB	CpcD phycobilisome linker domain protein
HPC62_RS03205	ENOG41078GB	pbs lyase
HPC62_RS03210	ENOG4108V9J	phycocyanobilin lyase
HPC62_RS03215	ENOG4106BTU	phycobilisome rod-core linker polypeptide
HPC62_RS03220	ENOG4106BTU	phycobilisome rod-core linker polypeptide
HPC62_RS03230	ENOG4106Q05	Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes (By similarity)
HPC62_RS03235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_RS03250	ENOG4108UXN	response regulator
HPC62_RS03255	ENOG4105BZU	Histidine kinase
HPC62_RS03260	ENOG4105BZU	Histidine kinase
HPC62_RS03265	ENOG4105BZU	Histidine kinase
HPC62_RS03275	ENOG4107VRP	DNA repair exonuclease
HPC62_RS03290	ENOG4105C6X	Major Facilitator
HPC62_RS03315	ENOG4108PJD	permease
HPC62_RS03355	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_RS03360	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HPC62_RS03375	ENOG4105J0U	photosystem II
HPC62_RS03390	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HPC62_RS03410	ENOG4105VGQ	Photosystem I subunit X
HPC62_RS03445	ENOG4105DX0	Hemolysin A
HPC62_RS03455	ENOG4105PFC	Transcriptional regulator
HPC62_RS03460	ENOG4108JGH	Tetr family transcriptional regulator
HPC62_RS03470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPC62_RS03490	ENOG4105DRP	amino acid AbC transporter
HPC62_RS03495	ENOG4105EZ7	amino acid ABC transporter
HPC62_RS03500	ENOG4107QXX	ABC transporter
HPC62_RS03535	ENOG4105C0H	protease
HPC62_RS03555	ENOG4107RH8	nuclease SbcCD subunit D
HPC62_RS03590	ENOG4105D3Q	Sugar transferase
HPC62_RS03630	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPC62_RS03635	ENOG4108MRH	transcriptional regulatory protein
HPC62_RS03640	ENOG41083EU	50s ribosomal protein l28
HPC62_RS03720	ENOG41082AN	stage II sporulation protein
HPC62_RS03735	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPC62_RS03740	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HPC62_RS03745	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPC62_RS03765	ENOG4105D7N	magnesium and cobalt transport protein CorA
HPC62_RS03770	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HPC62_RS03790	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HPC62_RS03800	ENOG4107WDG	serine threonine protein kinase
HPC62_RS03810	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_RS03815	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPC62_RS03820	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HPC62_RS03870	ENOG4108KMV	Glycosyl transferase (Group 1
HPC62_RS03895	ENOG4107Z3D	50S ribosomal protein l10
HPC62_RS03900	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HPC62_RS03905	ENOG4105JKW	Valine--pyruvate aminotransferase
HPC62_RS03920	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HPC62_RS03940	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HPC62_RS03950	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HPC62_RS03960	ENOG4105DFU	Cell wall formation (By similarity)
HPC62_RS03965	ENOG4105D4A	Cell wall formation (By similarity)
HPC62_RS04010	ENOG4105CDH	Citrulline--aspartate ligase
HPC62_RS04015	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS04025	ENOG4105EN6	Membrane
HPC62_RS04035	ENOG4107TS3	membrane protein, TerC
HPC62_RS04040	ENOG4105CFP	Peptidase U32
HPC62_RS04050	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HPC62_RS04055	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HPC62_RS04070	ENOG4107RFW	hydrolase family 57
HPC62_RS04110	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HPC62_RS04120	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HPC62_RS04125	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HPC62_RS04130	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HPC62_RS04140	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPC62_RS04205	ENOG4108KS2	transglutaminase domain protein
HPC62_RS04210	ENOG4105CJN	penicillin-binding protein
HPC62_RS04215	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HPC62_RS04220	ENOG4105IJJ	transcriptional regulator, crp fnr family
HPC62_RS04235	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HPC62_RS04245	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HPC62_RS04260	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HPC62_RS04265	ENOG4105EET	magnesium chelatase
HPC62_RS04280	ENOG4105KVH	Transcriptional regulator
HPC62_RS04290	ENOG4107VQD	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HPC62_RS04295	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPC62_RS04315	ENOG4105BZA	Phosphoglycerate kinase
HPC62_RS04320	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HPC62_RS04340	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HPC62_RS04375	ENOG4105WIA	photosystem II reaction center protein H
HPC62_RS04380	ENOG410686T	photosystem II reaction center protein N
HPC62_RS04400	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
HPC62_RS04410	ENOG4105DAA	L-lactate
HPC62_RS04430	ENOG4108R6K	riboflavin synthase, subunit alpha
HPC62_RS04435	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HPC62_RS04470	ENOG4107QHF	type ii secretion system protein e
HPC62_RS04475	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS04480	ENOG41088CC	tellurite resistance protein tehB
HPC62_RS04490	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HPC62_RS04505	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HPC62_RS04550	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HPC62_RS04555	ENOG4105D3G	Pseudouridine synthase
HPC62_RS04570	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HPC62_RS04585	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_RS04590	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_RS04605	ENOG41084H8	Binds directly to 16S ribosomal RNA (By similarity)
HPC62_RS04620	ENOG4105J3Z	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPC62_RS04635	ENOG41084GC	stage II sporulation protein
HPC62_RS04640	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPC62_RS04650	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPC62_RS04660	ENOG4105CQC	Prephenate dehydratase
HPC62_RS04665	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HPC62_RS04670	ENOG4105VF7	tolerance protein
HPC62_RS04680	ENOG4108KXV	response regulator
HPC62_RS04690	ENOG4105D0C	transport protein
HPC62_RS04705	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HPC62_RS04710	ENOG41067HS	methyltransferase
HPC62_RS04720	ENOG4105C59	p-type ATPase
HPC62_RS04730	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HPC62_RS04740	ENOG4105CPQ	Dehydrogenase
HPC62_RS04745	ENOG410612X	Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane
HPC62_RS04750	ENOG4105DRS	transport system, permease
HPC62_RS04755	ENOG4105CPC	Aldo Keto reductase
HPC62_RS04765	ENOG4105E66	phosphoriboisomerase A
HPC62_RS04780	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HPC62_RS04790	ENOG4105DCI	Phosphohydrolase
HPC62_RS04795	ENOG4105CMI	transporter
HPC62_RS04800	ENOG4105CJ1	ABC, transporter
HPC62_RS04805	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_RS04810	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HPC62_RS04820	ENOG4105CXI	aluminum resistance protein
HPC62_RS04830	ENOG4105BZU	Histidine kinase
HPC62_RS04840	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS04860	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HPC62_RS04895	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HPC62_RS04940	ENOG4105CVJ	phosphoglycerate mutase
HPC62_RS04950	ENOG4108JQC	penicillin-binding protein 1A
HPC62_RS04955	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HPC62_RS05030	ENOG4107RCV	ABC transporter, permease
HPC62_RS05045	ENOG4105C6K	Malic enzyme
HPC62_RS05050	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HPC62_RS05090	ENOG4105FDK	ABC transporter
HPC62_RS05095	ENOG4105FAV	ABC, transporter
HPC62_RS05140	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HPC62_RS05165	ENOG4105D85	methylase
HPC62_RS05285	ENOG4105CNI	cell division protein FtsW
HPC62_RS05305	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HPC62_RS05340	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS05350	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_RS05355	ENOG41084IE	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_RS05365	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPC62_RS05380	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPC62_RS05405	ENOG4108S59	
HPC62_RS05415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPC62_RS05430	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_RS05435	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPC62_RS05450	ENOG4105E4F	Isochorismate synthase
HPC62_RS05465	ENOG4105W5Q	DNA repair protein (RadC
HPC62_RS05480	ENOG4105EWK	phytoene
HPC62_RS05485	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HPC62_RS05490	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HPC62_RS05520	ENOG4105DDQ	anthranilate synthase
HPC62_RS05540	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS05550	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HPC62_RS05560	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HPC62_RS05585	ENOG4105CDA	abc transporter atp-binding protein
HPC62_RS05590	ENOG4105E5Q	amino acid AbC transporter
HPC62_RS05635	ENOG4105HHA	aminodeoxychorismate lyase
HPC62_RS05640	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HPC62_RS05650	ENOG41060PK	NIL
HPC62_RS05660	ENOG4107Z6A	sulfate abc transporter permease
HPC62_RS05665	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HPC62_RS05670	ENOG4105CKI	cobalamin synthesis protein
HPC62_RS05680	ENOG4105CFH	Aspartokinase
HPC62_RS05685	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HPC62_RS05705	ENOG4107Y1F	Involved in the transcription termination process (By similarity)
HPC62_RS05740	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HPC62_RS05745	ENOG4105DFF	Rod shape-determining protein mreb
HPC62_RS05750	ENOG41080E3	single-stranded DNA-binding protein
HPC62_RS05760	ENOG4105C1Q	protoporphyrinogen oxidase
HPC62_RS05765	ENOG4105CJN	penicillin-binding protein
HPC62_RS05770	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS05775	ENOG4107RUE	extracellular solute-binding protein family 1
HPC62_RS05780	ENOG4105F38	ABC transporter, permease
HPC62_RS05785	ENOG4105D38	putrescine abc transporter
HPC62_RS05790	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPC62_RS05825	ENOG4105CGZ	zinc metallopeptidase
HPC62_RS05840	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HPC62_RS05845	ENOG4108HW3	(ABC) transporter
HPC62_RS05855	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
HPC62_RS05870	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPC62_RS05875	ENOG4105Q36	FHA domain containing protein
HPC62_RS05900	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_RS05910	ENOG4105CPJ	photosystem II manganese-stabilizing
HPC62_RS05925	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS05950	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HPC62_RS06040	ENOG4105CVB	Vitamin K epoxide reductase
HPC62_RS06045	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_RS06060	ENOG4105E54	alpha-amylase
HPC62_RS06070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS06080	ENOG4105DWV	Homoserine O-trans-acetylase
HPC62_RS06085	ENOG4105CHR	reductase
HPC62_RS06125	ENOG4107WDG	serine threonine protein kinase
HPC62_RS06145	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPC62_RS06170	ENOG4105C8M	UPF0272 protein
HPC62_RS06190	ENOG4105CHH	sulfate transporter
HPC62_RS06195	ENOG41082SX	arsR family transcriptional regulator
HPC62_RS06220	ENOG4107S17	Phosphate-binding protein
HPC62_RS06250	ENOG4106I2R	Coenzyme F420 hydrogenase dehydrogenase, beta
HPC62_RS06275	ENOG4107JDS	UPF0102 protein
HPC62_RS06315	ENOG4108Z66	YbaK ebsC protein
HPC62_RS06335	ENOG4105DXN	mazG family
HPC62_RS06345	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_RS06350	ENOG4107WMZ	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HPC62_RS06365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPC62_RS06405	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HPC62_RS06445	ENOG4105C3Q	Glycosyl transferase, family 2
HPC62_RS06485	ENOG4105CQB	FAD linked oxidase domain protein
HPC62_RS06545	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HPC62_RS06575	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS06580	ENOG4105GR3	Histidine kinase
HPC62_RS06625	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPC62_RS06710	ENOG4108IJ8	ABC transporter
HPC62_RS06715	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HPC62_RS06740	ENOG4108JYK	Dehydrogenase
HPC62_RS06745	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS06770	ENOG4105BZU	Histidine kinase
HPC62_RS06835	ENOG4108TJN	glycosyl transferase group 1
HPC62_RS06850	ENOG4108RVA	ribokinase
HPC62_RS06855	ENOG4107QUY	Guanine deaminase
HPC62_RS06865	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
HPC62_RS06885	ENOG4105C2W	permease
HPC62_RS06890	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_RS06915	ENOG4107U9T	Pfam:Ribonuclease_BN
HPC62_RS06940	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPC62_RS06980	ENOG4105CJN	penicillin-binding protein
HPC62_RS07000	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPC62_RS07020	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HPC62_RS07025	ENOG41082QS	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HPC62_RS07080	ENOG4105XEV	csbD-like
HPC62_RS07135	ENOG4105M08	Membrane
HPC62_RS07145	ENOG4105C8N	cysteinyl-tRNA synthetase
HPC62_RS07170	ENOG4105C0B	DNA polymerase III (alpha subunit)
HPC62_RS07180	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_RS07190	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HPC62_RS07200	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPC62_RS07215	ENOG4108HM4	ABC transporter
HPC62_RS07275	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPC62_RS07285	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HPC62_RS07295	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_RS07300	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS07305	ENOG4105D64	Mechanosensitive ion channel
HPC62_RS07340	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPC62_RS07350	ENOG41086VY	Fic/DOC family
HPC62_RS07355	ENOG4105E1F	short-chain dehydrogenase reductase
HPC62_RS07365	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPC62_RS07375	ENOG4107XFE	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HPC62_RS07400	ENOG4105JFG	SpoIID LytB domain protein
HPC62_RS07405	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
HPC62_RS07445	ENOG4105DB7	PHP domain protein
HPC62_RS07450	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HPC62_RS07460	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HPC62_RS07515	ENOG4105H3G	oxidoreductase
HPC62_RS07520	ENOG4105C26	Dehydrogenase
HPC62_RS07540	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HPC62_RS07545	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HPC62_RS07550	ENOG4105CDU	Replicative dna helicase
HPC62_RS07575	ENOG4105C5H	ABC transporter
HPC62_RS07615	ENOG4106ASF	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex (By similarity)
HPC62_RS07625	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HPC62_RS07635	ENOG4105ECY	inositol monophosphatase
HPC62_RS07695	ENOG410801B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HPC62_RS07740	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPC62_RS07755	ENOG4108ZF3	Phosphatase
HPC62_RS07765	ENOG4105BZU	Histidine kinase
HPC62_RS07795	ENOG4105C8Q	Methyl-accepting chemotaxis
HPC62_RS07810	ENOG4108UNF	response regulator
HPC62_RS07825	ENOG4105C01	Dihydroxy-acid dehydratase
HPC62_RS07870	ENOG410848W	30S ribosomal protein S21
HPC62_RS07875	ENOG4105VFU	Rna-binding protein
HPC62_RS07880	ENOG4105CNG	UPF0061 protein
HPC62_RS07885	ENOG4105C7K	acetolactate synthase
HPC62_RS07895	ENOG4108E2B	had-superfamily hydrolase, subfamily iib
HPC62_RS07915	ENOG4105CBX	hi0933 family
HPC62_RS07925	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_RS07930	ENOG4105D3Q	Sugar transferase
HPC62_RS07980	ENOG4108TNP	
HPC62_RS07985	ENOG4105C9B	Cysteine desulfurase
HPC62_RS08005	ENOG4105PWN	phosphate abc transporter
HPC62_RS08035	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HPC62_RS08045	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HPC62_RS08050	ENOG4107ZYR	domain protein
HPC62_RS08055	ENOG4105CZN	Potassium uptake protein
HPC62_RS08085	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HPC62_RS08110	ENOG4105CXN	decarboxylase
HPC62_RS08115	ENOG4105ES5	Histidine kinase
HPC62_RS08125	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_RS08130	ENOG4107ZH9	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HPC62_RS08155	ENOG4105FBB	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) (By similarity)
HPC62_RS08200	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HPC62_RS08205	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPC62_RS08215	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HPC62_RS08220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS08230	ENOG4105CQB	FAD linked oxidase domain protein
HPC62_RS08235	ENOG4105BZU	Histidine kinase
HPC62_RS08240	ENOG4105CD8	aminopeptidase N
HPC62_RS08255	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPC62_RS08265	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HPC62_RS08285	ENOG4107XWB	Zinc finger, swim domain protein
HPC62_RS08350	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPC62_RS08355	ENOG4105CMQ	Chloride channel
HPC62_RS08360	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS08395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HPC62_RS08405	ENOG4105BZU	Histidine kinase
HPC62_RS08445	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
HPC62_RS08450	ENOG4105CBT	Fructose-1,6-bisphosphatase
HPC62_RS08475	ENOG4105BZU	Histidine kinase
HPC62_RS08480	ENOG4105DFK	Polyphosphate glucokinase
HPC62_RS08485	ENOG4107U7Q	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HPC62_RS08495	ENOG4105BZ1	(ABC) transporter
HPC62_RS08515	ENOG4105NXP	Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity)
HPC62_RS08545	ENOG4107RSS	Hydrogenase accessory protein HypB
HPC62_RS08575	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HPC62_RS08580	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HPC62_RS08585	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_RS08590	ENOG4105VYJ	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_RS08600	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPC62_RS08610	ENOG4105PA3	atp synthase
HPC62_RS08615	ENOG4107SWE	Methyltransferase
HPC62_RS08625	ENOG4105EQK	-acetyltransferase
HPC62_RS08630	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HPC62_RS08650	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HPC62_RS08780	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPC62_RS08835	ENOG4105CHM	Aminotransferase
HPC62_RS08845	ENOG4105CQM	Urea amidohydrolase subunit alpha
HPC62_RS08865	ENOG4105BZU	Histidine kinase
HPC62_RS08870	ENOG4105BZU	Histidine kinase
HPC62_RS08875	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS08900	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HPC62_RS08910	ENOG4108IUZ	ABC transporter
HPC62_RS08955	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HPC62_RS08965	ENOG4105DBI	uridine monophosphokinase
HPC62_RS08975	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPC62_RS08995	ENOG4105D3Q	Sugar transferase
HPC62_RS09120	ENOG41082AN	stage II sporulation protein
HPC62_RS09135	ENOG4105EMN	RNA polymerase sigma factor
HPC62_RS09140	ENOG4105C72	UPF0176 protein
HPC62_RS09150	ENOG4105CNF	WD-40 repeat protein
HPC62_RS09155	ENOG4105DIH	basic membrane
HPC62_RS09160	ENOG4105UIB	(ABC) transporter
HPC62_RS09175	ENOG4108JQ9	ABC transporter
HPC62_RS09185	ENOG4105C5S	asparaginyl-tRNA synthetase
HPC62_RS09240	ENOG4105KME	endoribonuclease L-psp
HPC62_RS09245	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HPC62_RS09250	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HPC62_RS09275	ENOG4106TD9	Diguanylate cyclase
HPC62_RS09325	ENOG4105CJW	magnesium transporter
HPC62_RS09330	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HPC62_RS09335	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HPC62_RS09415	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPC62_RS09420	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HPC62_RS09435	ENOG4105CHH	sulfate transporter
HPC62_RS09490	ENOG4105D5K	Hemolysin activator protein
HPC62_RS09505	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
HPC62_RS09520	ENOG4105BZU	Histidine kinase
HPC62_RS09540	ENOG4105CUT	histidyl-tRNA synthetase
HPC62_RS09550	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_RS09565	ENOG4106PMH	Extracellular solute-binding protein family 3
HPC62_RS09570	ENOG4105E5Q	amino acid AbC transporter
HPC62_RS09615	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HPC62_RS09640	ENOG4105CRK	lysyL-tRNA synthetase
HPC62_RS09645	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HPC62_RS09725	ENOG4105GVR	general secretion pathway protein D
HPC62_RS09730	ENOG4105K70	DNA-binding protein
HPC62_RS09735	ENOG4107QZB	decarboxylase
HPC62_RS09740	ENOG4105C7Z	Conserved Protein
HPC62_RS09755	ENOG4106PMH	Extracellular solute-binding protein family 3
HPC62_RS09770	ENOG4105BZU	Histidine kinase
HPC62_RS09775	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HPC62_RS09785	ENOG4105C75	arginyL-tRNA synthetase
HPC62_RS09800	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HPC62_RS09820	ENOG4105BZU	Histidine kinase
HPC62_RS09825	ENOG4105CTK	cobaltochelatase, cobn subunit
HPC62_RS09855	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HPC62_RS09880	ENOG4105BZU	Histidine kinase
HPC62_RS09885	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HPC62_RS09910	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPC62_RS09940	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_RS09960	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HPC62_RS09990	ENOG41061MV	Arylsulfatase
HPC62_RS10020	ENOG4105D74	hydrolase
HPC62_RS10025	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_RS10045	ENOG4108JQC	penicillin-binding protein 1A
HPC62_RS10065	ENOG4105K8N	protein family UPF0079, ATPase
HPC62_RS10070	ENOG4105C6E	dna polymerase iii
HPC62_RS10105	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HPC62_RS10115	ENOG4105DHP	deoxycytidine triphosphate deaminase
HPC62_RS10150	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HPC62_RS10155	ENOG4105C6E	dna polymerase iii
HPC62_RS10160	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HPC62_RS10210	ENOG4105DA5	(ABC) transporter
HPC62_RS10225	ENOG4105DGU	Histone deacetylase
HPC62_RS10250	ENOG4107XZ0	Peptidase M50
HPC62_RS10260	ENOG4105BZU	Histidine kinase
HPC62_RS10265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS10285	ENOG4107WJM	-acetyltransferase
HPC62_RS10295	ENOG4105CSR	polyphosphate kinase 2
HPC62_RS10305	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS10310	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HPC62_RS10315	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPC62_RS10325	ENOG4105CEY	Amp-dependent synthetase and ligase
HPC62_RS10340	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPC62_RS10350	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HPC62_RS10355	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPC62_RS10380	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HPC62_RS10390	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HPC62_RS10405	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS10425	ENOG4105C8B	TIGR00159 family
HPC62_RS10435	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HPC62_RS10450	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HPC62_RS10475	ENOG41072GX	Peptidase M22 Glycoprotease
HPC62_RS10530	ENOG4105E0C	molybdate abc transporter
HPC62_RS10535	ENOG4108IJ6	ABC transporter
HPC62_RS10540	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HPC62_RS10560	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HPC62_RS10565	ENOG4107XM9	(LipO)protein
HPC62_RS10585	ENOG4105BZF	Glycosyl transferase (Group 1
HPC62_RS10620	ENOG4107S73	homocitrate synthase
HPC62_RS10625	ENOG4108JA1	polyketide synthase
HPC62_RS10640	ENOG4105CHR	reductase
HPC62_RS10675	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPC62_RS10680	ENOG4108062	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPC62_RS10685	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HPC62_RS10695	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPC62_RS10700	ENOG4105C0Z	ABC transporter
HPC62_RS10740	ENOG4105C31	Tryptophanyl-tRNA synthetase
HPC62_RS10750	ENOG4105E0X	reductase
HPC62_RS10755	ENOG4105EB3	Histidine kinase
HPC62_RS10760	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS10785	ENOG4105D4Y	metalloprotease
HPC62_RS10790	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_RS10800	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HPC62_RS10810	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HPC62_RS10815	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HPC62_RS10875	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPC62_RS10895	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HPC62_RS10945	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPC62_RS11020	ENOG4105CQR	helicase
HPC62_RS11030	ENOG4105C8T	Leucyl-tRNA synthetase
HPC62_RS11045	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HPC62_RS11055	ENOG41085FC	arsR family transcriptional regulator
HPC62_RS11060	ENOG4105C1J	atp-dependent rna helicase
HPC62_RS11065	ENOG41063SB	peptidase
HPC62_RS11075	ENOG4108YXU	transcriptional regulator AsnC family
HPC62_RS11080	ENOG4105D0M	Protease HtpX homolog
HPC62_RS11085	ENOG4105C8Y	Acetylornithine aminotransferase
HPC62_RS11120	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPC62_RS11210	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HPC62_RS11215	ENOG4105X1F	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration (By similarity)
HPC62_RS11240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HPC62_RS11285	ENOG4105MPN	Membrane
HPC62_RS11300	ENOG4105BZU	Histidine kinase
HPC62_RS11350	ENOG4105DCF	alanine dehydrogenase
HPC62_RS11360	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPC62_RS11370	ENOG4105BZU	Histidine kinase
HPC62_RS11380	ENOG4107E2E	PKHD-type hydroxylase
HPC62_RS11430	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HPC62_RS11510	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPC62_RS11520	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPC62_RS11525	ENOG4108VCT	Sulfite exporter TauE/SafE
HPC62_RS11545	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HPC62_RS11570	ENOG41088CC	tellurite resistance protein tehB
HPC62_RS11575	ENOG4105ND9	Nitrogenase-associated protein
HPC62_RS11580	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HPC62_RS11620	ENOG4105D7W	serine acetyltransferase
HPC62_RS11645	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
HPC62_RS11675	ENOG4108UR2	Nitrogen fixation protein NifX
HPC62_RS11680	ENOG4108VQE	nitrogen fixation protein
HPC62_RS11685	ENOG4108NWW	ferritin dps family protein
HPC62_RS11690	ENOG4107S73	homocitrate synthase
HPC62_RS11765	ENOG4105C0D	helicase
HPC62_RS11850	ENOG4105BZU	Histidine kinase
HPC62_RS11860	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HPC62_RS11870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HPC62_RS11875	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HPC62_RS11880	ENOG4108Z6M	essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA B D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin cytochrome c6- ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn
HPC62_RS11895	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_RS11900	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HPC62_RS11910	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_RS11935	ENOG4107R0E	Glycosyl transferase, family 2
HPC62_RS11955	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HPC62_RS11965	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HPC62_RS11970	ENOG4105CJ1	ABC, transporter
HPC62_RS11975	ENOG4106PVI	ATP-dependent carboxylate-amine ligase (By similarity)
HPC62_RS11980	ENOG4105F32	YngK protein
HPC62_RS11990	ENOG4105CSR	polyphosphate kinase 2
HPC62_RS11995	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
HPC62_RS12020	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HPC62_RS12030	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HPC62_RS12035	ENOG4105EUJ	GTP cyclohydrolase i
HPC62_RS12055	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_RS12060	ENOG41076QQ	Glycosyl transferase, family 2
HPC62_RS12080	ENOG4108JJA	ABC, transporter
HPC62_RS12130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPC62_RS12180	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HPC62_RS12190	ENOG4108SKZ	Patatin-like phospholipase
HPC62_RS12200	ENOG4107WZZ	SMC domain protein
HPC62_RS12215	ENOG4107XW6	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HPC62_RS12225	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HPC62_RS12250	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPC62_RS12255	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_RS12260	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPC62_RS12280	ENOG4106F1P	AAA ATPase, central domain protein
HPC62_RS12290	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HPC62_RS12320	ENOG4108E1C	hydrolase
HPC62_RS12325	ENOG4105CNW	domain protein
HPC62_RS12340	ENOG4105CNW	domain protein
HPC62_RS12350	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS12405	ENOG4105E6M	Sulphatase-modifying factor protein
HPC62_RS12430	ENOG4107QPR	SAICAR synthetase
HPC62_RS12480	ENOG4105MSA	Photosystem II reaction center W protein
HPC62_RS12485	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HPC62_RS12540	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HPC62_RS12560	ENOG4105DAY	polysaccharide export protein
HPC62_RS12600	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPC62_RS12610	ENOG4105N6Y	Thioredoxin
HPC62_RS12630	ENOG4105C5I	Dehydrogenase
HPC62_RS12640	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HPC62_RS12645	ENOG4105D5U	fad dependent oxidoreductase
HPC62_RS12650	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_RS12655	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_RS12665	ENOG4105DAY	polysaccharide export protein
HPC62_RS12700	ENOG4105U3E	Transcriptional regulator
HPC62_RS12710	ENOG4105D2N	Aldolase
HPC62_RS12715	ENOG4108JJB	ABC transporter
HPC62_RS12720	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HPC62_RS12730	ENOG4108IJ9	(ABC) transporter
HPC62_RS12740	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HPC62_RS12750	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPC62_RS12755	ENOG4105NZG	Ferredoxin
HPC62_RS12770	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HPC62_RS12775	ENOG4105D0M	Protease HtpX homolog
HPC62_RS12780	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HPC62_RS12820	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPC62_RS12825	ENOG4107QHF	type ii secretion system protein e
HPC62_RS12830	ENOG4105CZX	twitching motility protein
HPC62_RS12900	ENOG4105Y3U	Transglycosylase-associated protein
HPC62_RS12930	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HPC62_RS12950	ENOG4108IYU	L-aspartate oxidase
HPC62_RS12970	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HPC62_RS13020	ENOG4108IUW	ABC transporter
HPC62_RS13030	ENOG4105WXN	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HPC62_RS13040	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HPC62_RS13065	ENOG4105BZ1	(ABC) transporter
HPC62_RS13070	ENOG4105K64	Glycosyl transferase, family 2
HPC62_RS13075	ENOG4105K64	Glycosyl transferase, family 2
HPC62_RS13080	ENOG4105CPK	Glycosyl transferase (Group 1
HPC62_RS13105	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HPC62_RS13125	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HPC62_RS13135	ENOG4106CD9	glycosyl transferase group 1
HPC62_RS13140	ENOG4108WF2	Metal Dependent Phosphohydrolase
HPC62_RS13165	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HPC62_RS13175	ENOG4105BZ1	(ABC) transporter
HPC62_RS13185	ENOG4105H63	Glycosyl transferase, family 2
HPC62_RS13210	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_RS13215	ENOG4105DAY	polysaccharide export protein
HPC62_RS13220	ENOG4107YJ4	chain length determinant protein
HPC62_RS13245	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HPC62_RS13255	ENOG4107VAM	peptidase, m28
HPC62_RS13260	ENOG4105CPC	Aldo Keto reductase
HPC62_RS13270	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_RS13320	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS13325	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_RS13330	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS13335	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS13345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS13365	ENOG4105BZ1	(ABC) transporter
HPC62_RS13370	ENOG4107YJ4	chain length determinant protein
HPC62_RS13410	ENOG4108JQ6	ABC transporter
HPC62_RS13420	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HPC62_RS13425	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HPC62_RS13445	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_RS13450	ENOG4105DR5	peptidase
HPC62_RS13485	ENOG4107R21	site-determining protein
HPC62_RS13495	ENOG4105BZU	Histidine kinase
HPC62_RS13505	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
HPC62_RS13510	ENOG4105EHU	Circadian clock protein KaiC
HPC62_RS13530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_RS13535	ENOG4105BZU	Histidine kinase
HPC62_RS13580	ENOG4105CD3	dihydroorotase
HPC62_RS13595	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HPC62_RS13600	ENOG4105CIK	Amidinotransferase
HPC62_RS13650	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HPC62_RS13660	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_RS13665	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS13695	ENOG4105EYW	Ion transport protein
HPC62_RS13755	ENOG4105CVJ	phosphoglycerate mutase
HPC62_RS13770	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HPC62_RS13805	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HPC62_RS13810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HPC62_RS13825	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPC62_RS13870	ENOG4105D0M	Protease HtpX homolog
HPC62_RS13885	ENOG4105BZU	Histidine kinase
HPC62_RS13940	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HPC62_RS13990	ENOG41065W4	chlorophyll a b binding light harvesting protein
HPC62_RS13995	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HPC62_RS14005	ENOG4105DSE	periplasmic solute binding protein
HPC62_RS14060	ENOG4105F32	YngK protein
HPC62_RS14075	ENOG4105D9R	oxidoreductase
HPC62_RS14080	ENOG4105ETX	regulatoR
HPC62_RS14095	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HPC62_RS14115	ENOG4105K63	Thioredoxin
HPC62_RS14120	ENOG4105D49	3-dehydroquinate synthase
HPC62_RS14140	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPC62_RS14145	ENOG4105CJW	magnesium transporter
HPC62_RS14155	ENOG4107ZYJ	bioY protein
HPC62_RS14160	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPC62_RS14165	ENOG410828V	rubredoxin
HPC62_RS14180	ENOG410689D	This b-type cytochrome is tightly associated with the reaction center of photosystem II and possibly is part of the water-oxidation complex (By similarity)
HPC62_RS14255	ENOG4105D9N	nucleoside
HPC62_RS14260	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_RS14270	ENOG4105BZU	Histidine kinase
HPC62_RS14275	ENOG4108Z6B	deaminase
HPC62_RS14280	ENOG4105C3M	thioredoxin reductase
HPC62_RS14320	ENOG4105BZU	Histidine kinase
HPC62_RS14345	ENOG4107E2E	PKHD-type hydroxylase
HPC62_RS14350	ENOG4108Z0R	Transferase
HPC62_RS14365	ENOG4108HMN	Caspase domain
HPC62_RS14370	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HPC62_RS14375	ENOG4105CMR	udp-glucose 4-epimerase
HPC62_RS14420	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_RS14430	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HPC62_RS14450	ENOG4108SHN	Glycosyl transferase, family 2
HPC62_RS14455	ENOG41064K2	Hepn domain protein
HPC62_RS14490	ENOG41082AN	stage II sporulation protein
HPC62_RS14525	ENOG4105D52	delta-aminolevulinic acid dehydratase
HPC62_RS14535	ENOG4105EMU	Dehydrogenase
HPC62_RS14595	ENOG4105D5K	Hemolysin activator protein
HPC62_RS14610	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPC62_RS14615	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HPC62_RS14620	ENOG4108VHT	MarR family transcriptional regulator
HPC62_RS14645	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HPC62_RS14690	ENOG4105D9R	oxidoreductase
HPC62_RS14705	ENOG4108UNF	response regulator
HPC62_RS14730	ENOG4107RCI	amp-dependent synthetase and ligase
HPC62_RS14735	ENOG4107T9Q	phosphonate abc transporter
HPC62_RS14740	ENOG4105D5T	phosphonate abc transporter
HPC62_RS14750	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
HPC62_RS14755	ENOG4105CZX	twitching motility protein
HPC62_RS14760	ENOG4107S5T	Carbohydrate kinase
HPC62_RS14780	ENOG4105EMU	Dehydrogenase
HPC62_RS14790	ENOG4105FE1	phytoene synthase
HPC62_RS14800	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HPC62_RS14805	ENOG4105C5F	glutamine synthetase
HPC62_RS14925	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
HPC62_RS14930	ENOG4108RCM	Nitroreductase
HPC62_RS14990	ENOG4105CP9	extracellular ligand-binding receptor
HPC62_RS15060	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPC62_RS15075	ENOG4105C5H	ABC transporter
HPC62_RS15095	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HPC62_RS15100	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HPC62_RS15140	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HPC62_RS15145	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HPC62_RS15175	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
HPC62_RS15180	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS15195	ENOG4105BZU	Histidine kinase
HPC62_RS15260	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HPC62_RS15310	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HPC62_RS15375	ENOG4105BZU	Histidine kinase
HPC62_RS15410	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_RS15430	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HPC62_RS15440	ENOG4105BZ1	(ABC) transporter
HPC62_RS15490	ENOG41088PD	hydrolase
HPC62_RS15500	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HPC62_RS15535	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HPC62_RS15610	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_RS15615	ENOG4105BZU	Histidine kinase
HPC62_RS15640	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HPC62_RS15645	ENOG4105C5I	Dehydrogenase
HPC62_RS15650	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HPC62_RS15670	ENOG41080W8	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HPC62_RS15700	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS15705	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPC62_RS15720	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HPC62_RS15780	ENOG4105C8U	phosphate abc transporter
HPC62_RS15785	ENOG4105E2Z	phosphate ABC transporter (Permease
HPC62_RS15790	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS15815	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HPC62_RS15845	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HPC62_RS15885	ENOG4105X25	
HPC62_RS15900	ENOG4105BZU	Histidine kinase
HPC62_RS15905	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_RS15925	ENOG41086BQ	Protein CrcB homolog
HPC62_RS15940	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HPC62_RS15955	ENOG4105C2I	pirin domain protein
HPC62_RS15965	ENOG4105KVH	Transcriptional regulator
HPC62_RS16025	ENOG4105CJ1	ABC, transporter
HPC62_RS16030	ENOG4108JUA	Transcriptional regulator
HPC62_RS16035	ENOG4107YCR	Transcriptional regulator, ARSR family
HPC62_RS16050	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPC62_RS16070	ENOG4105C26	Dehydrogenase
HPC62_RS16075	ENOG4105C5F	glutamine synthetase
HPC62_RS16080	ENOG4105NVB	glycoside hydrolase, family 19
HPC62_RS16090	ENOG4107QRT	dEAD DEAH box helicase
HPC62_RS16220	ENOG4105CDA	abc transporter atp-binding protein
HPC62_RS16245	ENOG4105DR4	Methyltransferase
HPC62_RS16270	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPC62_RS16295	ENOG41082EZ	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HPC62_RS16310	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HPC62_RS16335	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPC62_RS16340	ENOG4105PGM	cation diffusion facilitator family transporter
HPC62_RS16365	ENOG4107T3P	ABC, transporter
HPC62_RS16435	ENOG4107QRP	cobalamin biosynthesis protein CobW
HPC62_RS16465	ENOG4105D8X	mechanosensitive ion channel
HPC62_RS16490	ENOG4108V5V	Serine Threonine protein kinase
HPC62_RS16520	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPC62_RS16565	ENOG4105VN1	Heat shock protein
HPC62_RS16610	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HPC62_RS16620	ENOG4108Q5Y	Membrane
HPC62_RS16625	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HPC62_RS16655	ENOG4107VC8	ATP cone domain protein
HPC62_RS16720	ENOG4107Y9U	Membrane
HPC62_RS16730	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HPC62_RS16740	ENOG4105ETX	regulatoR
HPC62_RS16770	ENOG4105KI2	Urea amidohydrolase subunit beta
HPC62_RS16775	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HPC62_RS16780	ENOG4107UAN	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HPC62_RS16790	ENOG4105CRE	cytochrome C
HPC62_RS16805	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
HPC62_RS16860	ENOG4108JQ6	ABC transporter
HPC62_RS16865	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPC62_RS16880	ENOG4107RAQ	aminopeptidase
HPC62_RS16895	ENOG4105CD2	stage iii sporulation protein aa
HPC62_RS16910	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
HPC62_RS16915	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPC62_RS16920	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPC62_RS16940	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_RS16950	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HPC62_RS17030	ENOG4105BZU	Histidine kinase
HPC62_RS17035	ENOG4105VFU	Rna-binding protein
HPC62_RS17050	ENOG4107QZ7	Cellulose synthase catalytic subunit
HPC62_RS17060	ENOG4105M3Z	response regulator
HPC62_RS17130	ENOG4105DRS	transport system, permease
HPC62_RS17160	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HPC62_RS17170	ENOG4105YVZ	photosystem II
HPC62_RS17180	ENOG4106DDF	Photosystem II reaction center protein M
HPC62_RS17185	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_RS17190	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HPC62_RS17195	ENOG4105C19	ABC transporter
HPC62_RS17200	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPC62_RS17215	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS17230	ENOG4105M0M	Tetracycline resistance protein
HPC62_RS17240	ENOG4107EPV	Aminotransferase class V
HPC62_RS17265	ENOG41082FX	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HPC62_RS17300	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPC62_RS17325	ENOG41083MR	nifu domain-containing protein
HPC62_RS17340	ENOG4107R7Y	intracellular protease Pfpi family
HPC62_RS17385	ENOG4105BZU	Histidine kinase
HPC62_RS17395	ENOG4105BZU	Histidine kinase
HPC62_RS17410	ENOG4107QKW	extracellular solute-binding protein family 1
HPC62_RS17430	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_RS17450	ENOG4105C85	amino acid
HPC62_RS17485	ENOG4107VUB	phosphate binding protein
HPC62_RS17495	ENOG4107ZR3	Required for maturation of 30S ribosomal subunits (By similarity)
HPC62_RS17500	ENOG4105CHV	Transcription elongation factor NusA
HPC62_RS17525	ENOG4105EYH	Exonuclease
HPC62_RS17540	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HPC62_RS17560	ENOG4106R7G	Glycoside hydrolase family 5
HPC62_RS17575	ENOG4107SM8	Adenylate Guanylate cyclase
HPC62_RS17600	ENOG4105JNK	Glycosyl transferase (Group 1
HPC62_RS17605	ENOG4105CPK	Glycosyl transferase (Group 1
HPC62_RS17630	ENOG4105CEV	competence damage-inducible protein
HPC62_RS17635	ENOG4105ESV	Glycosyl transferase, family 4
HPC62_RS17655	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPC62_RS17690	ENOG4105C0D	helicase
HPC62_RS17695	ENOG4107TCE	N-acetyltransferase
HPC62_RS17715	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_RS17720	ENOG4105D0M	Protease HtpX homolog
HPC62_RS17735	ENOG4105VXP	Protein of unknown function DUF86
HPC62_RS17740	ENOG4108Y85	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_RS17745	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPC62_RS17790	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPC62_RS17795	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPC62_RS17800	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HPC62_RS17810	ENOG4105BZ1	(ABC) transporter
HPC62_RS17830	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
HPC62_RS17835	ENOG4105E9X	Photosystem II 44 kDa subunit reaction center protein
HPC62_RS17840	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HPC62_RS17865	ENOG4105C8Y	Acetylornithine aminotransferase
HPC62_RS17870	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HPC62_RS17875	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HPC62_RS17900	ENOG4107TVC	Glycosyl transferase, family 2
HPC62_RS17925	ENOG4107RIX	inner membrane protein translocase component YidC
HPC62_RS17940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPC62_RS17965	ENOG4108R85	Short chain dehydrogenase
HPC62_RS18030	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HPC62_RS18035	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS18040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS18045	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HPC62_RS18065	ENOG4105WVZ	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPC62_RS18085	ENOG4107RAQ	aminopeptidase
HPC62_RS18095	ENOG4107KHP	This protein is a component of the reaction center of photosystem II (By similarity)
HPC62_RS18120	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HPC62_RS18125	ENOG4105BZU	Histidine kinase
HPC62_RS18135	ENOG4105BZU	Histidine kinase
HPC62_RS18140	ENOG4105WH1	Two component transcriptional regulator luxr family
HPC62_RS18145	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPC62_RS18155	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HPC62_RS18170	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPC62_RS18175	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HPC62_RS18205	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HPC62_RS18210	ENOG4108IUK	alpha amylase, catalytic
HPC62_RS18225	ENOG4105E09	nadh pyrophosphatase
HPC62_RS18255	ENOG4105FR1	rard protein
HPC62_RS18285	ENOG4105BZU	Histidine kinase
HPC62_RS18290	ENOG4105E4C	Lytic transglycosylase catalytic
HPC62_RS18295	ENOG4105BZU	Histidine kinase
HPC62_RS18350	ENOG4105CVA	phosphate
HPC62_RS18400	ENOG4105CPQ	Dehydrogenase
HPC62_RS18405	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HPC62_RS18420	ENOG4105C37	(CBS) domain
HPC62_RS18430	ENOG4108ZCU	PPIases accelerate the folding of proteins
HPC62_RS18435	ENOG4105D65	subunit l
HPC62_RS18440	ENOG4105C8S	subunit m
HPC62_RS18460	ENOG4105BZ8	glutamate synthase
HPC62_RS18475	ENOG4105D8X	mechanosensitive ion channel
HPC62_RS18490	ENOG4106WTF	Glycosyl transferase, family 2
HPC62_RS18495	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPC62_RS18525	ENOG4108UQX	Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II (By similarity)
HPC62_RS18530	ENOG4105M3Z	response regulator
HPC62_RS18550	ENOG4105CEN	a g-specific adenine glycosylase
HPC62_RS18565	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS18570	ENOG4107R0W	ABC transporter
HPC62_RS18575	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HPC62_RS18590	ENOG4106UY4	Inherit from COG: Scp-like extracellular
HPC62_RS18615	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS18645	ENOG4105D0M	Protease HtpX homolog
HPC62_RS18665	ENOG4105ETX	regulatoR
HPC62_RS18675	ENOG41061H0	Monooxygenase
HPC62_RS18680	ENOG4105VT2	5-hydroxyisourate hydrolase
HPC62_RS18690	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HPC62_RS18695	ENOG4105F1A	Pyruvate formate-lyase
HPC62_RS18710	ENOG4105C0A	alcohol dehydrogenase
HPC62_RS18745	ENOG4105CHM	Aminotransferase
HPC62_RS18785	ENOG4105CE4	GlcNAc 6-P deacetylase
HPC62_RS18790	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HPC62_RS18795	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPC62_RS18820	ENOG4105BZU	Histidine kinase
HPC62_RS18830	ENOG4108NWW	ferritin dps family protein
HPC62_RS18835	ENOG4105FFC	UPF0187 protein
HPC62_RS18840	ENOG4107RSM	transcriptional regulator
HPC62_RS18880	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HPC62_RS18905	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HPC62_RS18910	ENOG4105D0M	Protease HtpX homolog
HPC62_RS18950	ENOG4105C8S	subunit m
HPC62_RS18960	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
HPC62_RS18965	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HPC62_RS18970	ENOG4105MXK	Carbon dioxide concentrating mechanism protein
HPC62_RS18985	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_RS18995	ENOG4108ZF3	Phosphatase
HPC62_RS19025	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HPC62_RS19075	ENOG4105D0M	Protease HtpX homolog
HPC62_RS19105	ENOG4105DTQ	mandelate racemase muconate lactonizing
HPC62_RS19110	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HPC62_RS19115	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPC62_RS19120	ENOG4105DKP	glycosyl transferase, family 9
HPC62_RS19125	ENOG4105CYM	Glutathione S-transferase
HPC62_RS19130	ENOG4108Z6Z	Transcriptional regulator
HPC62_RS19165	ENOG4105DFE	Dna adenine methylase
HPC62_RS19210	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_RS19220	ENOG4105F95	Monooxygenase
HPC62_RS19225	ENOG4105C5F	glutamine synthetase
HPC62_RS19250	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HPC62_RS19290	ENOG4105MSA	Photosystem II reaction center W protein
HPC62_RS19295	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HPC62_RS19340	ENOG4108W6I	photosystem I reaction center protein subunit XI
HPC62_RS19355	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS19365	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HPC62_RS19385	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HPC62_RS19410	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HPC62_RS19415	ENOG4105C3M	thioredoxin reductase
HPC62_RS19420	ENOG4105BZU	Histidine kinase
HPC62_RS19425	ENOG4105CJP	fad dependent oxidoreductase
HPC62_RS19430	ENOG4105KZX	Pterin carbinolamine dehydratase
HPC62_RS19440	ENOG4105D81	ABC transporter, permease
HPC62_RS19450	ENOG4105D7T	ABC transporter
HPC62_RS19455	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS19470	ENOG4105DJZ	UPF0182 protein
HPC62_RS19485	ENOG4106855	Competence protein
HPC62_RS19490	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HPC62_RS19550	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPC62_RS19560	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPC62_RS19570	ENOG4106AST	May help in the organization of the PsaE and PsaF subunits (By similarity)
HPC62_RS19580	ENOG4105CI1	PTS System
HPC62_RS19585	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HPC62_RS19590	ENOG4108ZFD	Antibiotic biosynthesis monooxygenase
HPC62_RS19600	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS19610	ENOG4108KGH	TRANSCRIPTIONal
HPC62_RS19685	ENOG4107SGM	protein serine threonine phosphatase
HPC62_RS19710	ENOG4108KQJ	Type 11 methyltransferase
HPC62_RS19720	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HPC62_RS19730	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HPC62_RS19740	ENOG4106MP8	UPF0754 membrane protein
HPC62_RS19770	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HPC62_RS19790	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HPC62_RS19815	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
HPC62_RS19820	ENOG4107T0X	DNA ligase
HPC62_RS19825	ENOG4105BZU	Histidine kinase
HPC62_RS19830	ENOG4108Z86	Glutamine amidotransferase
HPC62_RS19835	ENOG4105CHR	reductase
HPC62_RS19850	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPC62_RS19855	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HPC62_RS19860	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HPC62_RS19865	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HPC62_RS19875	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HPC62_RS19910	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HPC62_RS19925	ENOG4107QJE	Chromosome Partitioning Protein
HPC62_RS19950	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
HPC62_RS19965	ENOG4105C0P	Mg chelatase subunit ChlI
HPC62_RS19980	ENOG4108WPJ	Ferritin-like domain
HPC62_RS20005	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HPC62_RS20010	ENOG4105D44	asparaginase
HPC62_RS20035	ENOG41081UC	Inherit from COG: Competence protein
HPC62_RS20045	ENOG4106855	Competence protein
HPC62_RS20055	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HPC62_RS20065	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HPC62_RS20095	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HPC62_RS20105	ENOG4105BZU	Histidine kinase
HPC62_RS20115	ENOG4108MV2	Involved in light-induced Na( )-dependent proton extrusion. Also seems to be involved in CO(2) transport (By similarity)
HPC62_RS20145	ENOG4108KXV	response regulator
HPC62_RS20175	ENOG4108IJ6	ABC transporter
HPC62_RS20180	ENOG4105CHW	UPF0052 protein
HPC62_RS20185	ENOG4105D7K	pfkb domain protein
HPC62_RS20215	ENOG4105CRQ	synthase (Component I)
HPC62_RS20265	ENOG4108VPT	UPF0234 protein
HPC62_RS20285	ENOG4105BZF	Glycosyl transferase (Group 1
HPC62_RS20295	ENOG41080UQ	Transcriptional regulator
HPC62_RS20310	ENOG4105DAY	polysaccharide export protein
HPC62_RS20315	ENOG4107YJ4	chain length determinant protein
HPC62_RS20330	ENOG4107T8Q	Glycosyl transferase (Group 1
HPC62_RS20340	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPC62_RS20345	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HPC62_RS20350	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
HPC62_RS20355	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPC62_RS20375	ENOG4105BZ1	(ABC) transporter
HPC62_RS20385	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HPC62_RS20410	ENOG4107UQD	Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity)
HPC62_RS20430	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HPC62_RS20445	ENOG4105BZU	Histidine kinase
HPC62_RS20475	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
HPC62_RS20490	ENOG4105E0R	Deoxyhypusine synthase
HPC62_RS20505	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HPC62_RS20510	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPC62_RS20530	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPC62_RS20540	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS20550	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HPC62_RS20570	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HPC62_RS20590	ENOG4105K64	Glycosyl transferase, family 2
HPC62_RS20595	ENOG4105DXI	Major Facilitator superfamily
HPC62_RS20620	ENOG4107QJE	Chromosome Partitioning Protein
HPC62_RS20660	ENOG4108UHU	Aldolase
HPC62_RS20695	ENOG4105CFG	Acts as a chaperone (By similarity)
HPC62_RS20705	ENOG4105EUB	pirin domain protein
HPC62_RS20820	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPC62_RS20835	ENOG4105D9N	nucleoside
HPC62_RS20845	ENOG4105CJ3	phosphate transporter
HPC62_RS20880	ENOG41061MD	high-affinity nickel-transporter
HPC62_RS20895	ENOG4105F8J	Adenylate Guanylate cyclase
HPC62_RS20920	ENOG4107Z8V	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPC62_RS20930	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_RS20935	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HPC62_RS20940	ENOG4105XCI	PucC protein
HPC62_RS20955	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HPC62_RS20960	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPC62_RS20985	ENOG4105CMG	Carbohydrate kinase
HPC62_RS21005	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPC62_RS21015	ENOG4105EEK	Polypeptide
HPC62_RS21045	ENOG4105CKK	Glycosyl transferase, family 2
HPC62_RS21060	ENOG4108DN8	FAD dependent oxidoreductase
HPC62_RS21065	ENOG4108Z2U	ureidoglycolate hydrolase
HPC62_RS21070	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HPC62_RS21085	ENOG4105KHC	sulfurtransferase
HPC62_RS21090	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPC62_RS21145	ENOG4105C8S	subunit m
HPC62_RS21150	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HPC62_RS21215	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HPC62_RS21250	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HPC62_RS21280	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HPC62_RS21310	ENOG41082HT	Binds the 23S rRNA (By similarity)
HPC62_RS21325	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HPC62_RS21330	ENOG4108ZT0	50S ribosomal protein l17
HPC62_RS21335	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPC62_RS21340	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HPC62_RS21365	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HPC62_RS21370	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HPC62_RS21375	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HPC62_RS21380	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HPC62_RS21390	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HPC62_RS21395	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPC62_RS21420	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HPC62_RS21425	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HPC62_RS21430	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HPC62_RS21440	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPC62_RS21450	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HPC62_RS21455	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HPC62_RS21465	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPC62_RS21470	ENOG4108SMZ	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_RS21475	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPC62_RS21480	ENOG4105DR5	peptidase
HPC62_RS21495	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPC62_RS21500	ENOG4105W8H	transhydrogenase (subunit alpha
HPC62_RS21505	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPC62_RS21525	ENOG4105CC5	ABC transporter
HPC62_RS21530	ENOG4105DIK	(ABC) transporter
HPC62_RS21535	ENOG4105DSE	periplasmic solute binding protein
HPC62_RS21545	ENOG4105EY5	This is one of the two reaction center proteins of photosystem II
HPC62_RS21560	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
HPC62_RS21575	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_RS21595	ENOG4105BZU	Histidine kinase
HPC62_RS21600	ENOG4105ETU	transcriptional activator (TenA
HPC62_RS21640	ENOG4105BZU	Histidine kinase
HPC62_RS21660	ENOG4108JQC	penicillin-binding protein 1A
HPC62_RS21670	ENOG4105DWF	phosphomethylpyrimidine kinase
HPC62_RS21705	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HPC62_RS21710	ENOG4105CT1	(ABC) transporter
HPC62_RS21715	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HPC62_RS21740	ENOG4108Z61	cytochrome c-550
HPC62_RS21750	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPC62_RS21765	ENOG4107RA4	Glycosyl transferase (Group 1
HPC62_RS21780	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
HPC62_RS21790	ENOG4105K8R	UPF0145 protein
HPC62_RS21795	ENOG4108IV0	ABC, transporter
HPC62_RS21800	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPC62_RS21805	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HPC62_RS21810	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS21905	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HPC62_RS21975	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPC62_RS21990	ENOG4108IV0	ABC, transporter
HPC62_RS21995	ENOG4105C0Z	ABC transporter
HPC62_RS22005	ENOG4105C32	Amino acid ABC transporter (Permease)
HPC62_RS22010	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HPC62_RS22035	ENOG4105BZU	Histidine kinase
HPC62_RS22040	ENOG4108ZAF	Molybdopterin
HPC62_RS22045	ENOG4105CGH	5'-nucleotidase
HPC62_RS22060	ENOG4105C8S	subunit m
HPC62_RS22065	ENOG4107XWZ	ferric uptake regulator
HPC62_RS22080	ENOG41067XK	integral membrane protein
HPC62_RS22090	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HPC62_RS22100	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HPC62_RS22130	ENOG4108IJ6	ABC transporter
HPC62_RS22140	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPC62_RS22160	ENOG410902C	phosphohistidine phosphatase, SixA
HPC62_RS22170	ENOG4108IJ0	Aspartate ammonia-lyase
HPC62_RS22190	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HPC62_RS22215	ENOG4108IQE	Amp-dependent synthetase and ligase
HPC62_RS22270	ENOG41060D5	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPC62_RS22280	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPC62_RS22285	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HPC62_RS22345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPC62_RS22385	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HPC62_RS22390	ENOG4105CE9	30S ribosomal protein S2
HPC62_RS22400	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPC62_RS22420	ENOG4105K63	Thioredoxin
HPC62_RS22435	ENOG4105Q84	sucrose synthase
HPC62_RS22440	ENOG4108JJB	ABC transporter
HPC62_RS22445	ENOG4105VUV	UPF0367 protein
HPC62_RS22450	ENOG4105D6H	One of the two reaction center proteins of photosystem II (PSII), D2 is needed for assembly of a stable PSII complex (By similarity)
HPC62_RS22460	ENOG4108PWY	Carbohydrate-selective porin OprB
HPC62_RS22475	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPC62_RS22485	ENOG4107U45	Cobalt transport protein
HPC62_RS22490	ENOG41081XD	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HPC62_RS22505	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HPC62_RS22510	ENOG4105E0X	reductase
HPC62_RS22525	ENOG4105C7N	Xanthine uracil vitamin C permease
HPC62_RS22530	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HPC62_RS22570	ENOG4105D38	putrescine abc transporter
HPC62_RS22585	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS22605	ENOG4105K64	Glycosyl transferase, family 2
HPC62_RS22610	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
HPC62_RS22615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPC62_RS22620	ENOG4105BZU	Histidine kinase
HPC62_RS22635	ENOG4105E2K	Glycosyl transferase (Group 1
HPC62_RS22665	ENOG410667J	hydrolase
HPC62_RS22690	ENOG4105C3G	gtp-binding protein
HPC62_RS22715	ENOG4107EEX	Cellulose synthase regulator protein
HPC62_RS22720	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HPC62_RS22765	ENOG4105E2X	shikimate dehydrogenase
HPC62_RS22770	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HPC62_RS22780	ENOG4105EWN	Heme oxygenase
HPC62_RS22795	ENOG4108P5B	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
HPC62_RS22800	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HPC62_RS22825	ENOG4105RRH	
HPC62_RS22835	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HPC62_RS22870	ENOG4105C59	p-type ATPase
HPC62_RS22875	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPC62_RS22880	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
HPC62_RS22905	ENOG4105E33	succinate dehydrogenase
HPC62_RS22915	ENOG4105C0H	protease