locus-tag	class	description
JTM80_RS00005	COG2885	chlorophyll binding
JTM80_RS00010	COG2885	chlorophyll binding
JTM80_RS00015	COG2133	pyrroloquinoline quinone binding
JTM80_RS00025	COG0174	glutamine synthetase
JTM80_RS00030	COG5002	protein histidine kinase activity
JTM80_RS00040	COG3437	response regulator, receiver
JTM80_RS00040	COG4999	Histidine kinase
JTM80_RS00040	COG3850	Histidine kinase
JTM80_RS00040	COG2205	protein histidine kinase activity
JTM80_RS00055	COG4636	protein conserved in cyanobacteria
JTM80_RS00060	COG0300	oxidoreductase activity
JTM80_RS00070	COG1074	ATP-dependent DNA helicase activity
JTM80_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
JTM80_RS00120	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JTM80_RS00135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS00155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JTM80_RS00160	COG1799	cell septum assembly
JTM80_RS00165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JTM80_RS00170	COG2234	aminopeptidase activity
JTM80_RS00175	COG1192	Involved in chromosome partitioning
JTM80_RS00185	COG5002	protein histidine kinase activity
JTM80_RS00190	COG0745	RESPONSE REGULATOR receiver
JTM80_RS00195	COG1192	Involved in chromosome partitioning
JTM80_RS00200	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JTM80_RS00215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JTM80_RS00230	COG0492	ferredoxin-NADP+ reductase activity
JTM80_RS00240	COG0360	Binds together with S18 to 16S ribosomal RNA
JTM80_RS00245	COG0179	Fumarylacetoacetate (FAA) hydrolase
JTM80_RS00260	COG1802	Transcriptional regulator
JTM80_RS00265	COG0525	valine-tRNA ligase activity
JTM80_RS00275	COG0194	GDP metabolic process
JTM80_RS00280	COG2052	Domain of unknown function (DUF370)
JTM80_RS00295	COG0604	alcohol dehydrogenase
JTM80_RS00295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JTM80_RS00295	COG3321	synthase
JTM80_RS00295	COG4221	oxidoreductase activity
JTM80_RS00300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS00305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JTM80_RS00315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JTM80_RS00315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JTM80_RS00320	COG0454	-acetyltransferase
JTM80_RS00355	COG0583	DNA-binding transcription factor activity
JTM80_RS00365	COG0668	transmembrane transport
JTM80_RS00385	COG2226	methyltransferase
JTM80_RS00395	COG0720	synthase
JTM80_RS00400	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS00410	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JTM80_RS00415	COG1045	serine acetyltransferase
JTM80_RS00420	COG0516	GMP reductase activity
JTM80_RS00420	COG0517	IMP dehydrogenase activity
JTM80_RS00430	COG0450	alkyl hydroperoxide reductase
JTM80_RS00435	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JTM80_RS00440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JTM80_RS00445	COG3429	Glucose-6-phosphate dehydrogenase subunit
JTM80_RS00445	COG3409	Peptidoglycan-binding domain 1 protein
JTM80_RS00500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JTM80_RS00515	COG1429	ligase activity, forming nitrogen-metal bonds
JTM80_RS00525	COG0459	protein refolding
JTM80_RS00530	COG0516	GMP reductase activity
JTM80_RS00555	COG0083	homoserine kinase activity
JTM80_RS00560	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JTM80_RS00565	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JTM80_RS00595	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JTM80_RS00620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JTM80_RS00625	COG1573	uracil-dna glycosylase
JTM80_RS00630	COG1252	NADH dehydrogenase
JTM80_RS00650	COG0071	Belongs to the small heat shock protein (HSP20) family
JTM80_RS00660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JTM80_RS00665	COG3594	Acyltransferase
JTM80_RS00675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JTM80_RS00690	COG0072	phenylalanine-tRNA ligase activity
JTM80_RS00690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTM80_RS00695	COG0515	serine threonine protein kinase
JTM80_RS00695	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS00710	COG0515	serine threonine protein kinase
JTM80_RS00720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JTM80_RS00730	COG2046	Belongs to the sulfate adenylyltransferase family
JTM80_RS00735	COG1266	CAAX protease self-immunity
JTM80_RS00745	COG0456	acetyltransferase
JTM80_RS00755	COG0564	pseudouridine synthase activity
JTM80_RS00775	COG0237	dephospho-CoA kinase activity
JTM80_RS00780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JTM80_RS00785	COG1413	lyase activity
JTM80_RS00790	COG1413	lyase activity
JTM80_RS00795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JTM80_RS00800	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JTM80_RS00805	COG0237	dephospho-CoA kinase activity
JTM80_RS00810	COG0237	dephospho-CoA kinase activity
JTM80_RS00815	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JTM80_RS00820	COG0217	transcriptional regulatory protein
JTM80_RS00830	COG0784	Response regulator, receiver
JTM80_RS00835	COG5002	protein histidine kinase activity
JTM80_RS00835	COG2205	protein histidine kinase activity
JTM80_RS00835	COG0784	Response regulator, receiver
JTM80_RS00870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JTM80_RS00875	COG0420	3'-5' exonuclease activity
JTM80_RS00885	COG0424	maF-like protein
JTM80_RS00890	COG2814	Major facilitator Superfamily
JTM80_RS00910	COG0701	Predicted permease
JTM80_RS00945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JTM80_RS00950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JTM80_RS00980	COG0138	bifunctional purine biosynthesis protein purh
JTM80_RS00990	COG3536	Protein conserved in bacteria
JTM80_RS01015	COG1480	7TM receptor with intracellular HD hydrolase
JTM80_RS01035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JTM80_RS01045	COG2197	response regulator
JTM80_RS01050	COG1309	transcriptional regulator
JTM80_RS01060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JTM80_RS01060	COG2169	Transcriptional regulator
JTM80_RS01080	COG0765	amino acid transport
JTM80_RS01085	COG4597	amino acid ABC transporter
JTM80_RS01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTM80_RS01125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS01140	COG0420	3'-5' exonuclease activity
JTM80_RS01175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JTM80_RS01190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JTM80_RS01195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JTM80_RS01210	COG1842	Phage shock protein A
JTM80_RS01215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JTM80_RS01220	COG4565	transcriptional regulatory protein
JTM80_RS01225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JTM80_RS01315	COG1366	Belongs to the anti-sigma-factor antagonist family
JTM80_RS01330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JTM80_RS01335	COG0131	Imidazoleglycerol-phosphate dehydratase
JTM80_RS01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JTM80_RS01355	COG0598	Magnesium transport protein CorA
JTM80_RS01360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JTM80_RS01365	COG0601	transmembrane transport
JTM80_RS01380	COG0745	RESPONSE REGULATOR receiver
JTM80_RS01390	COG0515	serine threonine protein kinase
JTM80_RS01390	COG3266	domain, Protein
JTM80_RS01400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JTM80_RS01405	COG0412	Dienelactone hydrolase
JTM80_RS01440	COG2319	Wd-40 repeat
JTM80_RS01445	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JTM80_RS01460	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS01465	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JTM80_RS01470	COG0250	Participates in transcription elongation, termination and antitermination
JTM80_RS01475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JTM80_RS01480	COG0081	regulation of translation
JTM80_RS01485	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JTM80_RS01490	COG0222	ribosome binding
JTM80_RS01495	COG3977	Valine--pyruvate aminotransferase
JTM80_RS01500	COG0170	dolichyl monophosphate biosynthetic process
JTM80_RS01510	COG1509	lysine 2,3-aminomutase activity
JTM80_RS01530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JTM80_RS01535	COG1309	transcriptional regulator
JTM80_RS01540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JTM80_RS01550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JTM80_RS01555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JTM80_RS01560	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JTM80_RS01570	COG0517	IMP dehydrogenase activity
JTM80_RS01570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JTM80_RS01570	COG0617	tRNA 3'-terminal CCA addition
JTM80_RS01600	COG0137	argininosuccinate synthase activity
JTM80_RS01615	COG2860	membrane
JTM80_RS01625	COG0861	Integral membrane protein TerC family
JTM80_RS01630	COG0826	peptidase U32
JTM80_RS01640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JTM80_RS01645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JTM80_RS01660	COG1543	Belongs to the glycosyl hydrolase 57 family
JTM80_RS01685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JTM80_RS01700	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JTM80_RS01710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JTM80_RS01715	COG0632	four-way junction helicase activity
JTM80_RS01720	COG0312	modulator of DNA gyrase
JTM80_RS01730	COG0542	response to heat
JTM80_RS01740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JTM80_RS01740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JTM80_RS01770	COG1131	(ABC) transporter
JTM80_RS01775	COG1131	(ABC) transporter
JTM80_RS01795	COG0123	including yeast histone deacetylase and acetoin utilization protein
JTM80_RS01800	COG1305	Transglutaminase-like
JTM80_RS01805	COG0768	penicillin binding
JTM80_RS01810	COG1218	3'(2'),5'-bisphosphate nucleotidase
JTM80_RS01815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS01830	COG1222	aaa ATPase
JTM80_RS01840	COG0346	lactoylglutathione lyase activity
JTM80_RS01855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JTM80_RS01860	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JTM80_RS01875	COG1733	regulation of RNA biosynthetic process
JTM80_RS01885	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JTM80_RS01890	COG0519	Catalyzes the synthesis of GMP from XMP
JTM80_RS01890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JTM80_RS01895	COG0515	serine threonine protein kinase
JTM80_RS01910	COG0589	response to stress
JTM80_RS01915	COG0126	phosphoglycerate kinase activity
JTM80_RS01920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JTM80_RS01935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JTM80_RS01935	COG0758	DNA mediated transformation
JTM80_RS01940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTM80_RS01970	COG0024	Methionine aminopeptidase
JTM80_RS02000	COG1691	(AIR) carboxylase
JTM80_RS02010	COG1620	l-lactate permease
JTM80_RS02035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JTM80_RS02075	COG0297	glycogen (starch) synthase activity
JTM80_RS02080	COG0500	methyltransferase
JTM80_RS02090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JTM80_RS02105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JTM80_RS02140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JTM80_RS02145	COG0564	pseudouridine synthase activity
JTM80_RS02160	COG0167	dihydroorotate dehydrogenase activity
JTM80_RS02170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JTM80_RS02175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JTM80_RS02180	COG0085	RNA polymerase activity
JTM80_RS02185	COG0084	hydrolase, TatD family'
JTM80_RS02190	COG0268	Binds directly to 16S ribosomal RNA
JTM80_RS02195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JTM80_RS02205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JTM80_RS02220	COG1366	Belongs to the anti-sigma-factor antagonist family
JTM80_RS02225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTM80_RS02230	COG1530	ribonuclease E activity
JTM80_RS02235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JTM80_RS02250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JTM80_RS02255	COG1324	tolerance protein
JTM80_RS02265	COG0745	RESPONSE REGULATOR receiver
JTM80_RS02275	COG0569	domain protein
JTM80_RS02275	COG2985	domain, Protein
JTM80_RS02295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JTM80_RS02300	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
JTM80_RS02310	COG2217	Heavy metal translocating P-type atpase
JTM80_RS02320	COG0456	acetyltransferase
JTM80_RS02330	COG1063	alcohol dehydrogenase
JTM80_RS02335	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JTM80_RS02340	COG0395	ABC-type sugar transport system, permease component
JTM80_RS02345	COG0667	Aldo Keto reductase
JTM80_RS02355	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JTM80_RS02370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JTM80_RS02375	COG0793	Belongs to the peptidase S41A family
JTM80_RS02380	COG1078	dGTPase activity
JTM80_RS02385	COG0842	Transport permease protein
JTM80_RS02390	COG1131	(ABC) transporter
JTM80_RS02395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS02400	COG0003	Pfam Anion-transporting ATPase
JTM80_RS02410	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JTM80_RS02415	COG1490	D-aminoacyl-tRNA deacylase activity
JTM80_RS02420	COG2205	protein histidine kinase activity
JTM80_RS02430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JTM80_RS02445	COG0445	tRNA wobble uridine modification
JTM80_RS02480	COG0751	glycine-tRNA ligase activity
JTM80_RS02505	COG0587	DNA-directed DNA polymerase activity
JTM80_RS02515	COG0587	DNA-directed DNA polymerase activity
JTM80_RS02520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JTM80_RS02535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JTM80_RS02540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JTM80_RS02600	COG3385	transposase activity
JTM80_RS02605	COG1840	ABC-type Fe3 transport system, periplasmic component
JTM80_RS02610	COG3842	ATPase activity
JTM80_RS02640	COG0857	belongs to the CobB CobQ family
JTM80_RS02640	COG0280	phosphate acetyltransferase
JTM80_RS02645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JTM80_RS02685	COG1121	(ABC) transporter
JTM80_RS02690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JTM80_RS02700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS02725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JTM80_RS02735	COG2095	MarC family integral membrane protein
JTM80_RS02755	COG1002	Type II restriction enzyme, methylase subunits
JTM80_RS02775	COG3385	transposase activity
JTM80_RS02825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JTM80_RS02835	COG1619	proteins homologs of microcin C7 resistance protein MccF
JTM80_RS02840	COG1361	Conserved repeat domain
JTM80_RS02865	COG2082	Precorrin-8x methylmutase
JTM80_RS02870	COG0772	Belongs to the SEDS family
JTM80_RS02890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JTM80_RS02900	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
JTM80_RS02905	COG2211	Major facilitator Superfamily
JTM80_RS02920	COG0484	heat shock protein binding
JTM80_RS02925	COG0740	serine-type endopeptidase activity
JTM80_RS02930	COG0740	serine-type endopeptidase activity
JTM80_RS02935	COG0740	serine-type endopeptidase activity
JTM80_RS02940	COG2304	oxidoreductase activity
JTM80_RS02945	COG1136	(ABC) transporter
JTM80_RS02955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JTM80_RS02960	COG2264	protein methyltransferase activity
JTM80_RS02965	COG1187	pseudouridine synthase activity
JTM80_RS02975	COG1640	4-alpha-glucanotransferase
JTM80_RS02990	COG0730	response to heat
JTM80_RS02995	COG0156	8-amino-7-oxononanoate synthase activity
JTM80_RS03010	COG0649	NAD binding
JTM80_RS03020	COG1575	Belongs to the MenA family. Type 1 subfamily
JTM80_RS03045	COG2003	Belongs to the UPF0758 family
JTM80_RS03070	COG1166	arginine decarboxylase activity
JTM80_RS03075	COG0105	UTP biosynthetic process
JTM80_RS03080	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS03080	COG0515	serine threonine protein kinase
JTM80_RS03105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JTM80_RS03110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JTM80_RS03120	COG3842	ATPase activity
JTM80_RS03130	COG0395	ABC-type sugar transport system, permease component
JTM80_RS03170	COG1126	abc transporter atp-binding protein
JTM80_RS03175	COG0765	amino acid transport
JTM80_RS03215	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JTM80_RS03225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JTM80_RS03230	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JTM80_RS03235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JTM80_RS03240	COG4208	sulfate ABC transporter
JTM80_RS03245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JTM80_RS03250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JTM80_RS03255	COG0523	cobalamin synthesis protein
JTM80_RS03260	COG0628	permease
JTM80_RS03265	COG0527	aspartate kinase activity
JTM80_RS03270	COG0363	glucosamine-6-phosphate deaminase activity
JTM80_RS03290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JTM80_RS03295	COG0552	protein localization to endoplasmic reticulum
JTM80_RS03310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JTM80_RS03330	COG1077	Cell shape determining protein MreB Mrl
JTM80_RS03335	COG0629	single-stranded DNA binding
JTM80_RS03345	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JTM80_RS03350	COG0768	penicillin binding
JTM80_RS03355	COG3842	ATPase activity
JTM80_RS03360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JTM80_RS03365	COG1176	ABC-type spermidine putrescine transport system, permease component I
JTM80_RS03370	COG1177	transmembrane transport
JTM80_RS03375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JTM80_RS03380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JTM80_RS03385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JTM80_RS03425	COG0275	rRNA processing
JTM80_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTM80_RS03440	COG0723	plastoquinol--plastocyanin reductase activity
JTM80_RS03450	COG0805	protein transport
JTM80_RS03455	COG0539	negative regulation of cytoplasmic translation
JTM80_RS03460	COG1716	ATPase activity
JTM80_RS03485	COG0740	serine-type endopeptidase activity
JTM80_RS03500	COG1191	sigma factor activity
JTM80_RS03505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTM80_RS03510	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JTM80_RS03510	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
JTM80_RS03525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JTM80_RS03535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JTM80_RS03545	COG1981	membrane
JTM80_RS03565	COG0405	Gamma-glutamyltransferase
JTM80_RS03615	COG4243	Vitamin k epoxide reductase
JTM80_RS03620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JTM80_RS03645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JTM80_RS03655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JTM80_RS03660	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS03665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS03675	COG0628	permease
JTM80_RS03680	COG0484	heat shock protein binding
JTM80_RS03685	COG0443	Heat shock 70 kDa protein
JTM80_RS03690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JTM80_RS03700	COG3266	domain, Protein
JTM80_RS03700	COG0515	serine threonine protein kinase
JTM80_RS03720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JTM80_RS03720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JTM80_RS03745	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JTM80_RS03765	COG0659	secondary active sulfate transmembrane transporter activity
JTM80_RS03770	COG0640	Transcriptional regulator
JTM80_RS03810	COG3848	Pyruvate phosphate dikinase
JTM80_RS03810	COG0574	Belongs to the PEP-utilizing enzyme family
JTM80_RS03830	COG4636	protein conserved in cyanobacteria
JTM80_RS03850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JTM80_RS03855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JTM80_RS03860	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JTM80_RS03865	COG1846	Transcriptional regulator
JTM80_RS03890	COG1333	cytochrome c biogenesis protein
JTM80_RS03895	COG0157	Belongs to the NadC ModD family
JTM80_RS03935	COG0673	inositol 2-dehydrogenase activity
JTM80_RS03940	COG2205	protein histidine kinase activity
JTM80_RS03955	COG0646	methionine synthase
JTM80_RS03955	COG1410	methionine synthase
JTM80_RS03965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS03970	COG0318	PFAM AMP-dependent synthetase and ligase
JTM80_RS03975	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
JTM80_RS03980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JTM80_RS03980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS03985	COG3639	organic phosphonate transmembrane transporter activity
JTM80_RS03990	COG4251	negative regulation of phosphorylation
JTM80_RS04000	COG1070	Carbohydrate kinase
JTM80_RS04020	COG4221	oxidoreductase activity
JTM80_RS04025	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
JTM80_RS04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JTM80_RS04040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JTM80_RS04045	COG0174	glutamine synthetase
JTM80_RS04050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS04080	COG0629	single-stranded DNA binding
JTM80_RS04095	COG2911	Protein conserved in bacteria
JTM80_RS04095	COG3266	domain, Protein
JTM80_RS04095	COG1361	Conserved repeat domain
JTM80_RS04105	COG4636	protein conserved in cyanobacteria
JTM80_RS04115	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JTM80_RS04120	COG2066	Belongs to the glutaminase family
JTM80_RS04155	COG2175	clavaminate synthase activity
JTM80_RS04165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JTM80_RS04170	COG0778	Nitroreductase
JTM80_RS04180	COG0616	signal peptide processing
JTM80_RS04215	COG2268	Band 7 protein
JTM80_RS04270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JTM80_RS04285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JTM80_RS04300	COG0488	(ABC) transporter
JTM80_RS04305	COG0772	Belongs to the SEDS family
JTM80_RS04325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JTM80_RS04330	COG1122	ATPase activity
JTM80_RS04380	COG3706	GGDEF domain
JTM80_RS04380	COG2203	Gaf domain
JTM80_RS04380	COG4251	negative regulation of phosphorylation
JTM80_RS04380	COG5001	Diguanylate cyclase
JTM80_RS04395	COG0415	Belongs to the DNA photolyase family
JTM80_RS04400	COG1192	Involved in chromosome partitioning
JTM80_RS04430	COG0784	Response regulator, receiver
JTM80_RS04430	COG4191	Histidine kinase
JTM80_RS04445	COG0009	L-threonylcarbamoyladenylate synthase
JTM80_RS04460	COG0601	transmembrane transport
JTM80_RS04470	COG0110	maltose O-acetyltransferase activity
JTM80_RS04475	COG0728	peptidoglycan biosynthetic process
JTM80_RS04480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JTM80_RS04490	COG0356	it plays a direct role in the translocation of protons across the membrane
JTM80_RS04495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JTM80_RS04500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JTM80_RS04505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JTM80_RS04510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JTM80_RS04515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JTM80_RS04520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JTM80_RS04525	COG1053	succinate dehydrogenase
JTM80_RS04555	COG0375	protein maturation
JTM80_RS04560	COG0010	Belongs to the arginase family
JTM80_RS04570	COG0723	plastoquinol--plastocyanin reductase activity
JTM80_RS04570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTM80_RS04580	COG2010	Cytochrome c
JTM80_RS04610	COG1132	(ABC) transporter
JTM80_RS04620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JTM80_RS04625	COG1940	carbohydrate kinase activity
JTM80_RS04650	COG2099	Precorrin-6x reductase
JTM80_RS04655	COG1494	fructose-1,6-bisphosphatase
JTM80_RS04660	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS04715	COG0481	GTPase activity
JTM80_RS04720	COG0709	Synthesizes selenophosphate from selenide and ATP
JTM80_RS04750	COG2226	methyltransferase
JTM80_RS04765	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JTM80_RS04790	COG0315	cyclic pyranopterin monophosphate synthase activity
JTM80_RS04820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS04830	COG4279	zinc finger
JTM80_RS04840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JTM80_RS04845	COG0740	serine-type endopeptidase activity
JTM80_RS04850	COG0544	peptidyl-prolyl cis-trans isomerase activity
JTM80_RS04855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JTM80_RS04860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JTM80_RS04865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JTM80_RS04875	COG0308	aminopeptidase N
JTM80_RS04885	COG0277	FAD linked oxidase domain protein
JTM80_RS04900	COG0538	isocitrate dehydrogenase activity
JTM80_RS04910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JTM80_RS04915	COG0193	aminoacyl-tRNA hydrolase activity
JTM80_RS04960	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JTM80_RS04965	COG1606	tRNA processing
JTM80_RS04975	COG0109	protoheme IX farnesyltransferase activity
JTM80_RS04985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JTM80_RS04990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JTM80_RS05000	COG5002	protein histidine kinase activity
JTM80_RS05005	COG1982	Orn Lys Arg decarboxylase major
JTM80_RS05010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JTM80_RS05030	COG0363	glucosamine-6-phosphate deaminase activity
JTM80_RS05050	COG2226	methyltransferase
JTM80_RS05055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JTM80_RS05060	COG0569	domain protein
JTM80_RS05065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JTM80_RS05075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JTM80_RS05095	COG0372	Belongs to the citrate synthase family
JTM80_RS05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS05125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JTM80_RS05150	COG0070	glutamate synthase
JTM80_RS05150	COG0069	glutamate synthase activity
JTM80_RS05150	COG0067	glutamate synthase
JTM80_RS05165	COG1049	propionate catabolic process, 2-methylcitrate cycle
JTM80_RS05185	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS05195	COG2081	HI0933 family
JTM80_RS05215	COG0561	phosphatase activity
JTM80_RS05225	COG0028	Belongs to the TPP enzyme family
JTM80_RS05230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JTM80_RS05235	COG0724	RNA recognition motif
JTM80_RS05240	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JTM80_RS05290	COG0129	dihydroxy-acid dehydratase activity
JTM80_RS05320	COG0840	transmembrane signaling receptor activity
JTM80_RS05325	COG2198	Histidine kinase
JTM80_RS05325	COG0784	Response regulator, receiver
JTM80_RS05325	COG0643	Histidine kinase
JTM80_RS05325	COG2198	Histidine kinase
JTM80_RS05325	COG0784	Response regulator, receiver
JTM80_RS05325	COG0643	Histidine kinase
JTM80_RS05355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JTM80_RS05365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JTM80_RS05370	COG0419	ATPase involved in DNA repair
JTM80_RS05390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JTM80_RS05395	COG0195	Participates in both transcription termination and antitermination
JTM80_RS05400	COG0779	Required for maturation of 30S ribosomal subunits
JTM80_RS05465	COG2197	response regulator
JTM80_RS05475	COG3487	Iron-regulated protein
JTM80_RS05480	COG3128	pkhd-type hydroxylase
JTM80_RS05485	COG1840	ABC-type Fe3 transport system, periplasmic component
JTM80_RS05500	COG4191	Histidine kinase
JTM80_RS05500	COG0784	Response regulator, receiver
JTM80_RS05520	COG0704	Plays a role in the regulation of phosphate uptake
JTM80_RS05530	COG0557	exoribonuclease II activity
JTM80_RS05545	COG1181	Belongs to the D-alanine--D-alanine ligase family
JTM80_RS05565	COG0693	protein deglycase activity
JTM80_RS05570	COG1803	Methylglyoxal synthase
JTM80_RS05570	COG1597	lipid kinase activity
JTM80_RS05580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JTM80_RS05595	COG1011	Hydrolase
JTM80_RS05600	COG1252	NADH dehydrogenase
JTM80_RS05605	COG1136	(ABC) transporter
JTM80_RS05605	COG0577	efflux transmembrane transporter activity
JTM80_RS05645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JTM80_RS05650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JTM80_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS05660	COG3118	belongs to the thioredoxin family
JTM80_RS05670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JTM80_RS05680	COG3688	RNA-binding protein containing a PIN domain
JTM80_RS05690	COG0154	amidase activity
JTM80_RS05695	COG0484	heat shock protein binding
JTM80_RS05705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JTM80_RS05710	COG0577	efflux transmembrane transporter activity
JTM80_RS05710	COG1136	(ABC) transporter
JTM80_RS05715	COG1136	(ABC) transporter
JTM80_RS05720	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JTM80_RS05725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTM80_RS05750	COG0504	CTP synthase activity
JTM80_RS05775	COG3063	Type IV pilus biogenesis stability protein PilW
JTM80_RS05780	COG0395	ABC-type sugar transport system, permease component
JTM80_RS05795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JTM80_RS05800	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JTM80_RS05820	COG2738	Putative neutral zinc metallopeptidase
JTM80_RS05840	COG0784	Response regulator, receiver
JTM80_RS05840	COG0643	Histidine kinase
JTM80_RS05840	COG2198	Histidine kinase
JTM80_RS05850	COG0840	transmembrane signaling receptor activity
JTM80_RS05850	COG2203	Gaf domain
JTM80_RS05865	COG0784	Response regulator, receiver
JTM80_RS05870	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS05885	COG0724	RNA recognition motif
JTM80_RS05890	COG5002	protein histidine kinase activity
JTM80_RS05945	COG2082	Precorrin-8x methylmutase
JTM80_RS05955	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JTM80_RS05960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JTM80_RS05980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JTM80_RS05985	COG0328	RNA-DNA hybrid ribonuclease activity
JTM80_RS05990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JTM80_RS05995	COG0457	Tetratricopeptide repeat
JTM80_RS06010	COG3854	ATPases associated with a variety of cellular activities
JTM80_RS06025	COG0006	proline dipeptidase activity
JTM80_RS06035	COG5322	oxidoreductase activity
JTM80_RS06040	COG0740	serine-type endopeptidase activity
JTM80_RS06045	COG4172	Belongs to the ABC transporter superfamily
JTM80_RS06060	COG3385	transposase activity
JTM80_RS06090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTM80_RS06095	COG2226	methyltransferase
JTM80_RS06100	COG0312	modulator of DNA gyrase
JTM80_RS06110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JTM80_RS06120	COG0037	tRNA processing
JTM80_RS06125	COG0831	urea catabolic process
JTM80_RS06130	COG0832	Belongs to the urease beta subunit family
JTM80_RS06160	COG0745	RESPONSE REGULATOR receiver
JTM80_RS06170	COG0671	phosphoesterase, PA-phosphatase related
JTM80_RS06180	COG0697	spore germination
JTM80_RS06255	COG3385	transposase activity
JTM80_RS06275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JTM80_RS06300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JTM80_RS06305	COG0697	spore germination
JTM80_RS06310	COG0583	DNA-binding transcription factor activity
JTM80_RS06315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JTM80_RS06345	COG0149	triose-phosphate isomerase activity
JTM80_RS06355	COG0071	Belongs to the small heat shock protein (HSP20) family
JTM80_RS06385	COG0398	Pfam SNARE associated Golgi protein
JTM80_RS06390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JTM80_RS06395	COG0398	Pfam SNARE associated Golgi protein
JTM80_RS06400	COG0628	permease
JTM80_RS06450	COG0107	imidazoleglycerol-phosphate synthase activity
JTM80_RS06460	COG2363	Small membrane protein
JTM80_RS06470	COG0215	cysteine-tRNA ligase activity
JTM80_RS06490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JTM80_RS06495	COG0587	DNA-directed DNA polymerase activity
JTM80_RS06500	COG0745	RESPONSE REGULATOR receiver
JTM80_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
JTM80_RS06510	COG4948	Mandelate Racemase Muconate Lactonizing
JTM80_RS06515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JTM80_RS06525	COG0829	nickel cation binding
JTM80_RS06535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTM80_RS06540	COG0303	'Molybdopterin
JTM80_RS06545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JTM80_RS06550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JTM80_RS06555	COG0557	exoribonuclease II activity
JTM80_RS06565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JTM80_RS06570	COG0788	formyltetrahydrofolate deformylase activity
JTM80_RS06580	COG1994	Peptidase M50
JTM80_RS06580	COG0517	IMP dehydrogenase activity
JTM80_RS06590	COG0135	phosphoribosylanthranilate isomerase activity
JTM80_RS06655	COG0784	Response regulator, receiver
JTM80_RS06655	COG2205	protein histidine kinase activity
JTM80_RS06655	COG5002	protein histidine kinase activity
JTM80_RS06665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JTM80_RS06685	COG0745	RESPONSE REGULATOR receiver
JTM80_RS06715	COG1280	lysine exporter protein (LysE YggA)
JTM80_RS06745	COG0537	adenosine 5'-monophosphoramidase activity
JTM80_RS06750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JTM80_RS06770	COG0515	serine threonine protein kinase
JTM80_RS06780	COG4249	Peptidase C14 caspase catalytic subunit p20
JTM80_RS06780	COG2319	Wd-40 repeat
JTM80_RS06785	COG1104	cysteine desulfurase activity
JTM80_RS06790	COG0004	ammonium transporteR
JTM80_RS06810	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS06830	COG0166	Belongs to the GPI family
JTM80_RS06840	COG0346	lactoylglutathione lyase activity
JTM80_RS06845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JTM80_RS06850	COG0509	glycine decarboxylation via glycine cleavage system
JTM80_RS06855	COG0750	zinc metalloprotease
JTM80_RS06860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JTM80_RS06865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JTM80_RS06875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JTM80_RS06880	COG0724	RNA recognition motif
JTM80_RS06890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JTM80_RS06900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JTM80_RS06905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JTM80_RS06915	COG2912	Transglutaminase-like superfamily
JTM80_RS06935	COG0148	phosphopyruvate hydratase activity
JTM80_RS06945	COG0440	acetolactate synthase activity
JTM80_RS06950	COG0574	Belongs to the PEP-utilizing enzyme family
JTM80_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JTM80_RS06970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JTM80_RS06995	COG3655	Transcriptional regulator
JTM80_RS07020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JTM80_RS07040	COG0811	peptide transport
JTM80_RS07045	COG0848	biopolymer transport protein
JTM80_RS07050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JTM80_RS07085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JTM80_RS07090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS07095	COG4372	Transposase
JTM80_RS07105	COG2189	Belongs to the N(4) N(6)-methyltransferase family
JTM80_RS07160	COG1132	(ABC) transporter
JTM80_RS07210	COG2204	response regulator
JTM80_RS07225	COG0387	Pfam Sodium calcium exchanger
JTM80_RS07285	COG0515	serine threonine protein kinase
JTM80_RS07300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS07310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JTM80_RS07325	COG0004	ammonium transporteR
JTM80_RS07335	COG1376	ErfK ybiS ycfS ynhG family protein
JTM80_RS07340	COG0571	ribonuclease III activity
JTM80_RS07345	COG2217	Heavy metal translocating P-type atpase
JTM80_RS07365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JTM80_RS07375	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JTM80_RS07380	COG0047	phosphoribosylformylglycinamidine synthase activity
JTM80_RS07400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JTM80_RS07405	COG0271	Belongs to the BolA IbaG family
JTM80_RS07415	COG1404	Belongs to the peptidase S8 family
JTM80_RS07415	COG4935	Belongs to the peptidase S8 family
JTM80_RS07425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JTM80_RS07435	COG5398	heme oxygenase
JTM80_RS07440	COG0439	Biotin carboxylase
JTM80_RS07445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JTM80_RS07450	COG0515	serine threonine protein kinase
JTM80_RS07460	COG0322	excinuclease ABC activity
JTM80_RS07490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JTM80_RS07495	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS07515	COG0012	GTP binding
JTM80_RS07530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JTM80_RS07540	COG0561	phosphatase activity
JTM80_RS07560	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS07570	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS07585	COG5002	protein histidine kinase activity
JTM80_RS07590	COG3842	ATPase activity
JTM80_RS07595	COG1177	transmembrane transport
JTM80_RS07600	COG0463	Glycosyl transferase, family 2
JTM80_RS07600	COG1216	Glycosyl transferase, family 2
JTM80_RS07620	COG3842	ATPase activity
JTM80_RS07635	COG1177	transmembrane transport
JTM80_RS07670	COG0697	spore germination
JTM80_RS07675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JTM80_RS07680	COG2252	PERMEase
JTM80_RS07690	COG0857	belongs to the CobB CobQ family
JTM80_RS07695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JTM80_RS07700	COG1304	FMN binding
JTM80_RS07705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JTM80_RS07715	COG0736	holo-[acyl-carrier-protein] synthase activity
JTM80_RS07720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JTM80_RS07725	COG1160	GTP binding
JTM80_RS07730	COG0484	heat shock protein binding
JTM80_RS07735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JTM80_RS07740	COG1959	2 iron, 2 sulfur cluster binding
JTM80_RS07745	COG3659	wide pore channel activity
JTM80_RS07750	COG2154	pterin-4-alpha-carbinolamine dehydratase
JTM80_RS07765	COG1122	ATPase activity
JTM80_RS07770	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS07780	COG0436	Aminotransferase
JTM80_RS07785	COG3118	belongs to the thioredoxin family
JTM80_RS07795	COG2203	Gaf domain
JTM80_RS07795	COG3706	GGDEF domain
JTM80_RS07795	COG4251	negative regulation of phosphorylation
JTM80_RS07795	COG5001	Diguanylate cyclase
JTM80_RS07800	COG0513	Belongs to the DEAD box helicase family
JTM80_RS07805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTM80_RS07810	COG0434	BtpA family
JTM80_RS07815	COG0052	Belongs to the universal ribosomal protein uS2 family
JTM80_RS07820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JTM80_RS07830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JTM80_RS07860	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS07865	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JTM80_RS07875	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS07875	COG0515	serine threonine protein kinase
JTM80_RS07900	COG2119	membrane
JTM80_RS07905	COG1959	2 iron, 2 sulfur cluster binding
JTM80_RS07925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JTM80_RS07930	COG1570	exodeoxyribonuclease VII activity
JTM80_RS07940	COG3385	transposase activity
JTM80_RS07950	COG1722	exodeoxyribonuclease VII activity
JTM80_RS07970	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS07975	COG1316	TRANSCRIPTIONal
JTM80_RS07995	COG0508	dehydrogenase complex catalyzes the overall conversion of
JTM80_RS08005	COG1022	Amp-dependent synthetase and ligase
JTM80_RS08030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JTM80_RS08050	COG1027	Aspartate ammonia-lyase
JTM80_RS08060	COG2062	phosphohistidine phosphatase, SixA
JTM80_RS08070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JTM80_RS08080	COG0747	negative chemotaxis
JTM80_RS08090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JTM80_RS08115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JTM80_RS08125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JTM80_RS08135	COG0762	integral membrane protein
JTM80_RS08150	COG0735	belongs to the Fur family
JTM80_RS08155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS08160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTM80_RS08165	COG0793	Belongs to the peptidase S41A family
JTM80_RS08170	COG0737	Belongs to the 5'-nucleotidase family
JTM80_RS08175	COG0314	molybdopterin synthase activity
JTM80_RS08190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JTM80_RS08240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JTM80_RS08240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JTM80_RS08260	COG0586	Pfam SNARE associated Golgi protein
JTM80_RS08300	COG1193	negative regulation of DNA recombination
JTM80_RS08310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JTM80_RS08330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JTM80_RS08365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JTM80_RS08375	COG0697	spore germination
JTM80_RS08385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JTM80_RS08390	COG0483	inositol monophosphate 1-phosphatase activity
JTM80_RS08395	COG0484	heat shock protein binding
JTM80_RS08400	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JTM80_RS08405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS08415	COG0393	Putative heavy-metal-binding
JTM80_RS08425	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS08440	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS08440	COG0297	glycogen (starch) synthase activity
JTM80_RS08455	COG0297	glycogen (starch) synthase activity
JTM80_RS08465	COG2010	Cytochrome c
JTM80_RS08475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JTM80_RS08490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JTM80_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTM80_RS08500	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JTM80_RS08505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JTM80_RS08520	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JTM80_RS08535	COG0351	phosphomethylpyrimidine kinase
JTM80_RS08565	COG3850	Histidine kinase
JTM80_RS08565	COG5002	protein histidine kinase activity
JTM80_RS08590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JTM80_RS08595	COG0572	uridine kinase
JTM80_RS08600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JTM80_RS08605	COG5002	protein histidine kinase activity
JTM80_RS08610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JTM80_RS08625	COG3659	wide pore channel activity
JTM80_RS08660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JTM80_RS08665	COG0803	Belongs to the bacterial solute-binding protein 9 family
JTM80_RS08670	COG1121	(ABC) transporter
JTM80_RS08675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JTM80_RS08710	COG0739	heme binding
JTM80_RS08715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JTM80_RS08725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTM80_RS08735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JTM80_RS08740	COG0088	Forms part of the polypeptide exit tunnel
JTM80_RS08745	COG0089	rRNA binding
JTM80_RS08750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JTM80_RS08755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JTM80_RS08760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JTM80_RS08765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JTM80_RS08770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JTM80_RS08775	COG0255	Belongs to the universal ribosomal protein uL29 family
JTM80_RS08780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JTM80_RS08785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JTM80_RS08790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JTM80_RS08795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JTM80_RS08800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JTM80_RS08805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JTM80_RS08810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JTM80_RS08815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JTM80_RS08820	COG0200	Binds to the 23S rRNA
JTM80_RS08825	COG0201	protein transport
JTM80_RS08830	COG0563	adenylate kinase activity
JTM80_RS08835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JTM80_RS08840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JTM80_RS08845	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JTM80_RS08850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JTM80_RS08855	COG0202	RNA polymerase activity
JTM80_RS08860	COG0203	ribosomal protein L17
JTM80_RS08865	COG0101	tRNA pseudouridine synthase activity
JTM80_RS08870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JTM80_RS08875	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JTM80_RS08880	COG0254	rRNA binding
JTM80_RS08885	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JTM80_RS08890	COG0330	HflC and HflK could
JTM80_RS08895	COG1473	amidohydrolase
JTM80_RS08910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JTM80_RS08915	COG0616	signal peptide processing
JTM80_RS08930	COG0497	DNA recombination
JTM80_RS08935	COG3266	domain, Protein
JTM80_RS08935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JTM80_RS08950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JTM80_RS08965	COG2273	Hydrolase Family 16
JTM80_RS08965	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JTM80_RS08970	COG1725	Transcriptional regulator
JTM80_RS08975	COG1253	flavin adenine dinucleotide binding
JTM80_RS09030	COG4191	Histidine kinase
JTM80_RS09035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JTM80_RS09040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS09060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JTM80_RS09065	COG1672	PFAM Archaeal ATPase
JTM80_RS09095	COG3437	response regulator, receiver
JTM80_RS09115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JTM80_RS09120	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JTM80_RS09125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTM80_RS09135	COG0463	Glycosyl transferase, family 2
JTM80_RS09155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JTM80_RS09155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JTM80_RS09170	COG0237	dephospho-CoA kinase activity
JTM80_RS09170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JTM80_RS09180	COG0009	L-threonylcarbamoyladenylate synthase
JTM80_RS09190	COG2890	protein-(glutamine-N5) methyltransferase activity
JTM80_RS09200	COG1070	Carbohydrate kinase
JTM80_RS09210	COG0025	NhaP-type Na H and K H
JTM80_RS09215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JTM80_RS09225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JTM80_RS09230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JTM80_RS09240	COG1522	sequence-specific DNA binding
JTM80_RS09250	COG3265	gluconokinase activity
JTM80_RS09255	COG3437	response regulator, receiver
JTM80_RS09265	COG0571	ribonuclease III activity
JTM80_RS09320	COG0572	uridine kinase
JTM80_RS09335	COG0306	phosphate transporter
JTM80_RS09345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JTM80_RS09355	COG2267	carboxylic ester hydrolase activity
JTM80_RS09360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JTM80_RS09365	COG0564	pseudouridine synthase activity
JTM80_RS09415	COG5002	protein histidine kinase activity
JTM80_RS09480	COG1741	Belongs to the pirin family
JTM80_RS09490	COG0443	Heat shock 70 kDa protein
JTM80_RS09510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JTM80_RS09525	COG0800	Aldolase
JTM80_RS09555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JTM80_RS09565	COG1192	Involved in chromosome partitioning
JTM80_RS09590	COG2814	Major facilitator Superfamily
JTM80_RS09595	COG1216	Glycosyl transferase, family 2
JTM80_RS09630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTM80_RS09630	COG2022	thiamine diphosphate biosynthetic process
JTM80_RS09650	COG0519	Catalyzes the synthesis of GMP from XMP
JTM80_RS09665	COG0484	heat shock protein binding
JTM80_RS09670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JTM80_RS09675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JTM80_RS09690	COG1899	peptidyl-lysine modification to peptidyl-hypusine
JTM80_RS09735	COG2205	protein histidine kinase activity
JTM80_RS09750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JTM80_RS09770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JTM80_RS09795	COG0653	protein targeting
JTM80_RS09800	COG0668	transmembrane transport
JTM80_RS09805	COG1132	(ABC) transporter
JTM80_RS09825	COG1088	dTDP-glucose 4,6-dehydratase activity
JTM80_RS09835	COG1091	dTDP-4-dehydrorhamnose reductase activity
JTM80_RS09865	COG0489	protein tyrosine kinase activity
JTM80_RS09885	COG0583	DNA-binding transcription factor activity
JTM80_RS09895	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS09915	COG1666	GTP binding
JTM80_RS09950	COG0024	Methionine aminopeptidase
JTM80_RS09990	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JTM80_RS09995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JTM80_RS10000	COG2203	Gaf domain
JTM80_RS10000	COG3706	GGDEF domain
JTM80_RS10000	COG5001	Diguanylate cyclase
JTM80_RS10000	COG4251	negative regulation of phosphorylation
JTM80_RS10005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JTM80_RS10010	COG0745	RESPONSE REGULATOR receiver
JTM80_RS10025	COG0542	response to heat
JTM80_RS10050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JTM80_RS10055	COG5002	protein histidine kinase activity
JTM80_RS10065	COG0259	pyridoxamine-phosphate oxidase activity
JTM80_RS10090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JTM80_RS10110	COG4968	Prepilin-type N-terminal cleavage methylation domain
JTM80_RS10115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JTM80_RS10120	COG1040	competence protein
JTM80_RS10145	COG1446	asparaginase
JTM80_RS10150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JTM80_RS10160	COG1420	regulation of RNA biosynthetic process
JTM80_RS10175	COG0783	Belongs to the Dps family
JTM80_RS10200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JTM80_RS10205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JTM80_RS10220	COG1192	Involved in chromosome partitioning
JTM80_RS10235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JTM80_RS10265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
JTM80_RS10265	COG0662	Cupin 2, conserved barrel domain protein
JTM80_RS10270	COG0316	Belongs to the HesB IscA family
JTM80_RS10275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JTM80_RS10280	COG0049	tRNA binding
JTM80_RS10285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JTM80_RS10290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JTM80_RS10295	COG0051	transcription antitermination factor activity, RNA binding
JTM80_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS10310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JTM80_RS10315	COG3852	Histidine kinase
JTM80_RS10320	COG1793	dna ligase
JTM80_RS10325	COG0546	phosphoglycolate phosphatase activity
JTM80_RS10330	COG1994	Peptidase M50
JTM80_RS10330	COG0517	IMP dehydrogenase activity
JTM80_RS10345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JTM80_RS10355	COG0625	glutathione transferase activity
JTM80_RS10365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JTM80_RS10385	COG3937	granule-associated protein
JTM80_RS10395	COG4399	Belongs to the UPF0754 family
JTM80_RS10400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JTM80_RS10410	COG0575	Belongs to the CDS family
JTM80_RS10415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JTM80_RS10420	COG2045	Belongs to the ComB family
JTM80_RS10425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JTM80_RS10435	COG0165	Argininosuccinate lyase
JTM80_RS10450	COG2208	phosphoserine phosphatase activity
JTM80_RS10455	COG0577	efflux transmembrane transporter activity
JTM80_RS10455	COG1136	(ABC) transporter
JTM80_RS10465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTM80_RS10500	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JTM80_RS10505	COG1518	maintenance of DNA repeat elements
JTM80_RS10505	COG1468	defense response to virus
JTM80_RS10515	COG1857	crispr-associated protein
JTM80_RS10520	COG2852	Protein conserved in bacteria
JTM80_RS10530	COG1203	CRISPR-associated helicase, Cas3
JTM80_RS10570	COG0321	lipoyl(octanoyl) transferase activity
JTM80_RS10575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JTM80_RS10580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JTM80_RS10600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JTM80_RS10605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JTM80_RS10610	COG0572	uridine kinase
JTM80_RS10620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JTM80_RS10630	COG0811	peptide transport
JTM80_RS10635	COG0848	biopolymer transport protein
JTM80_RS10675	COG0584	glycerophosphoryl diester phosphodiesterase
JTM80_RS10680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JTM80_RS10685	COG0058	SHG alpha-glucan phosphorylase activity
JTM80_RS10700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JTM80_RS10705	COG4191	Histidine kinase
JTM80_RS10710	COG5002	protein histidine kinase activity
JTM80_RS10730	COG0804	urea catabolic process
JTM80_RS10740	COG0436	Aminotransferase
JTM80_RS10770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JTM80_RS10775	COG1247	-acetyltransferase
JTM80_RS10795	COG0297	glycogen (starch) synthase activity
JTM80_RS10800	COG0501	Belongs to the peptidase M48B family
JTM80_RS10815	COG2361	Protein of unknown function DUF86
JTM80_RS10825	COG0556	nucleotide-excision repair
JTM80_RS10830	COG0463	Glycosyl transferase, family 2
JTM80_RS10835	COG0628	permease
JTM80_RS10870	COG0247	lactate metabolic process
JTM80_RS10875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JTM80_RS10885	COG1404	Belongs to the peptidase S8 family
JTM80_RS10885	COG4935	Belongs to the peptidase S8 family
JTM80_RS10895	COG1132	(ABC) transporter
JTM80_RS10905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JTM80_RS10925	COG1160	GTP binding
JTM80_RS10950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JTM80_RS10955	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JTM80_RS10960	COG0830	nickel cation binding
JTM80_RS10975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JTM80_RS10990	COG0501	Belongs to the peptidase M48B family
JTM80_RS10995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JTM80_RS11020	COG0243	molybdopterin cofactor binding
JTM80_RS11025	COG1116	anion transmembrane transporter activity
JTM80_RS11030	COG1116	anion transmembrane transporter activity
JTM80_RS11030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JTM80_RS11040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JTM80_RS11060	COG0583	DNA-binding transcription factor activity
JTM80_RS11065	COG3781	membrane
JTM80_RS11070	COG0783	Belongs to the Dps family
JTM80_RS11080	COG3706	GGDEF domain
JTM80_RS11080	COG5001	Diguanylate cyclase
JTM80_RS11080	COG2203	Gaf domain
JTM80_RS11080	COG4251	negative regulation of phosphorylation
JTM80_RS11085	COG0415	Belongs to the DNA photolyase family
JTM80_RS11090	COG1970	mechanosensitive ion channel activity
JTM80_RS11095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JTM80_RS11110	COG2308	Evidence 4 Homologs of previously reported genes of
JTM80_RS11130	COG0371	Dehydrogenase
JTM80_RS11135	COG0436	Aminotransferase
JTM80_RS11155	COG0672	)-iron permease
JTM80_RS11160	COG1733	regulation of RNA biosynthetic process
JTM80_RS11170	COG1454	alcohol dehydrogenase
JTM80_RS11170	COG1012	belongs to the aldehyde dehydrogenase family
JTM80_RS11180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JTM80_RS11190	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JTM80_RS11195	COG0574	Belongs to the PEP-utilizing enzyme family
JTM80_RS11195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JTM80_RS11200	COG2351	hydroxyisourate hydrolase activity
JTM80_RS11205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JTM80_RS11210	COG0745	RESPONSE REGULATOR receiver
JTM80_RS11230	COG0501	Belongs to the peptidase M48B family
JTM80_RS11240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JTM80_RS11245	COG1253	flavin adenine dinucleotide binding
JTM80_RS11260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JTM80_RS11265	COG1940	carbohydrate kinase activity
JTM80_RS11280	COG2340	Cysteine-rich secretory protein family
JTM80_RS11285	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JTM80_RS11295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JTM80_RS11300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTM80_RS11305	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS11310	COG5002	protein histidine kinase activity
JTM80_RS11315	COG1194	a g-specific adenine glycosylase
JTM80_RS11325	COG0251	oxidation-reduction process
JTM80_RS11340	COG2010	Cytochrome c
JTM80_RS11370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JTM80_RS11400	COG0668	transmembrane transport
JTM80_RS11405	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JTM80_RS11415	COG0493	'glutamate synthase
JTM80_RS11420	COG0067	glutamate synthase
JTM80_RS11420	COG0070	glutamate synthase
JTM80_RS11420	COG0069	glutamate synthase activity
JTM80_RS11430	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
JTM80_RS11440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS11445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTM80_RS11450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JTM80_RS11460	COG1253	flavin adenine dinucleotide binding
JTM80_RS11475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JTM80_RS11480	COG1063	alcohol dehydrogenase
JTM80_RS11490	COG0644	oxidoreductase
JTM80_RS11520	COG0058	SHG alpha-glucan phosphorylase activity
JTM80_RS11530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS11570	COG0454	-acetyltransferase
JTM80_RS11590	COG3852	Histidine kinase
JTM80_RS11595	COG0741	lytic transglycosylase activity
JTM80_RS11600	COG4251	negative regulation of phosphorylation
JTM80_RS11605	COG0784	Response regulator, receiver
JTM80_RS11610	COG2203	Gaf domain
JTM80_RS11610	COG4251	negative regulation of phosphorylation
JTM80_RS11610	COG5001	Diguanylate cyclase
JTM80_RS11610	COG3706	GGDEF domain
JTM80_RS11630	COG2962	Rard protein
JTM80_RS11645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JTM80_RS11655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JTM80_RS11660	COG2816	NAD+ diphosphatase activity
JTM80_RS11670	COG0366	Alpha amylase catalytic
JTM80_RS11675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JTM80_RS11680	COG0540	Belongs to the ATCase OTCase family
JTM80_RS11710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JTM80_RS11715	COG0539	negative regulation of cytoplasmic translation
JTM80_RS11730	COG1185	polyribonucleotide nucleotidyltransferase activity
JTM80_RS11740	COG0412	Dienelactone hydrolase
JTM80_RS11745	COG2197	response regulator
JTM80_RS11750	COG4251	negative regulation of phosphorylation
JTM80_RS11755	COG0784	Response regulator, receiver
JTM80_RS11760	COG4999	Histidine kinase
JTM80_RS11760	COG2205	protein histidine kinase activity
JTM80_RS11760	COG3437	response regulator, receiver
JTM80_RS11760	COG3850	Histidine kinase
JTM80_RS11765	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JTM80_RS11770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JTM80_RS11775	COG0469	pyruvate kinase activity
JTM80_RS11800	COG0006	proline dipeptidase activity
JTM80_RS11820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTM80_RS11835	COG0010	Belongs to the arginase family
JTM80_RS11840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JTM80_RS11845	COG3842	ATPase activity
JTM80_RS11850	COG1178	ABC-type Fe3 transport system permease component
JTM80_RS11855	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JTM80_RS11860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTM80_RS11875	COG0702	epimerase
JTM80_RS11895	COG1032	radical SAM domain protein
JTM80_RS11900	COG1116	anion transmembrane transporter activity
JTM80_RS11905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JTM80_RS11910	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS11935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS11950	COG0706	membrane insertase activity
JTM80_RS11960	COG0594	ribonuclease P activity
JTM80_RS11965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JTM80_RS11975	COG0457	Tetratricopeptide repeat
JTM80_RS11975	COG0463	Glycosyl transferase, family 2
JTM80_RS11990	COG0505	Belongs to the CarA family
JTM80_RS12010	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS12015	COG1216	Glycosyl transferase, family 2
JTM80_RS12020	COG1216	Glycosyl transferase, family 2
JTM80_RS12025	COG1132	(ABC) transporter
JTM80_RS12030	COG0489	protein tyrosine kinase activity
JTM80_RS12030	COG3206	protein involved in exopolysaccharide biosynthesis
JTM80_RS12050	COG0408	coproporphyrinogen oxidase activity
JTM80_RS12070	COG4555	ABC transporter
JTM80_RS12100	COG0489	protein tyrosine kinase activity
JTM80_RS12100	COG3206	protein involved in exopolysaccharide biosynthesis
JTM80_RS12120	COG1968	undecaprenyl-diphosphatase activity
JTM80_RS12140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JTM80_RS12155	COG2211	Major facilitator Superfamily
JTM80_RS12160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JTM80_RS12190	COG2261	transglycosylase associated protein
JTM80_RS12220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JTM80_RS12225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JTM80_RS12245	COG1459	type II secretion system
JTM80_RS12255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JTM80_RS12260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JTM80_RS12265	COG0443	Heat shock 70 kDa protein
JTM80_RS12270	COG0484	heat shock protein binding
JTM80_RS12280	COG1162	GTPase activity
JTM80_RS12285	COG4251	negative regulation of phosphorylation
JTM80_RS12285	COG5001	Diguanylate cyclase
JTM80_RS12285	COG2203	Gaf domain
JTM80_RS12285	COG3706	GGDEF domain
JTM80_RS12295	COG1196	nuclear chromosome segregation
JTM80_RS12300	COG0501	Belongs to the peptidase M48B family
JTM80_RS12310	COG0343	queuine tRNA-ribosyltransferase activity
JTM80_RS12320	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JTM80_RS12325	COG3411	Ferredoxin
JTM80_RS12330	COG0745	RESPONSE REGULATOR receiver
JTM80_RS12340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JTM80_RS12345	COG5001	Diguanylate cyclase
JTM80_RS12350	COG3842	ATPase activity
JTM80_RS12355	COG4251	negative regulation of phosphorylation
JTM80_RS12355	COG5001	Diguanylate cyclase
JTM80_RS12355	COG2203	Gaf domain
JTM80_RS12355	COG3706	GGDEF domain
JTM80_RS12360	COG0357	Ribosomal RNA small subunit methyltransferase G
JTM80_RS12365	COG1122	ATPase activity
JTM80_RS12380	COG1695	Transcriptional regulator
JTM80_RS12400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JTM80_RS12405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JTM80_RS12410	COG0142	geranyltranstransferase activity
JTM80_RS12420	COG0460	homoserine dehydrogenase
JTM80_RS12430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JTM80_RS12435	COG0579	oxidoreductase
JTM80_RS12440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JTM80_RS12450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JTM80_RS12455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS12465	COG1842	Phage shock protein A
JTM80_RS12470	COG3118	belongs to the thioredoxin family
JTM80_RS12475	COG0163	prenyltransferase activity
JTM80_RS12480	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JTM80_RS12480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JTM80_RS12485	COG0025	NhaP-type Na H and K H
JTM80_RS12490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JTM80_RS12520	COG1596	polysaccharide export
JTM80_RS12530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTM80_RS12540	COG1797	cobyrinic acid a,c-diamide synthase activity
JTM80_RS12545	COG2188	Transcriptional regulator
JTM80_RS12595	COG0521	Mo-molybdopterin cofactor biosynthetic process
JTM80_RS12625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JTM80_RS12630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JTM80_RS12635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JTM80_RS12640	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JTM80_RS12650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JTM80_RS12720	COG0484	heat shock protein binding
JTM80_RS12740	COG0426	domain, Protein
JTM80_RS12740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JTM80_RS12755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JTM80_RS12755	COG0426	domain, Protein
JTM80_RS12760	COG3409	Peptidoglycan-binding domain 1 protein
JTM80_RS12760	COG0860	N-Acetylmuramoyl-L-alanine amidase
JTM80_RS12775	COG0515	serine threonine protein kinase
JTM80_RS12780	COG3385	transposase activity
JTM80_RS12785	COG0515	serine threonine protein kinase
JTM80_RS12790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JTM80_RS12795	COG0110	maltose O-acetyltransferase activity
JTM80_RS12805	COG0464	growth
JTM80_RS12830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS12835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS12840	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS12865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JTM80_RS12870	COG2894	cell division
JTM80_RS12875	COG0850	regulation of cytokinetic process
JTM80_RS12890	COG0419	ATPase involved in DNA repair
JTM80_RS12895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JTM80_RS12900	COG1752	Esterase of the alpha-beta hydrolase superfamily
JTM80_RS12910	COG3046	protein related to deoxyribodipyrimidine photolyase
JTM80_RS12925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JTM80_RS12960	COG0154	amidase activity
JTM80_RS13005	COG1672	PFAM Archaeal ATPase
JTM80_RS13005	COG2319	Wd-40 repeat
JTM80_RS13030	COG0463	Glycosyl transferase, family 2
JTM80_RS13035	COG3659	wide pore channel activity
JTM80_RS13055	COG0302	gtp cyclohydrolase
JTM80_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS13065	COG0825	malonyl-CoA metabolic process
JTM80_RS13085	COG0534	Mate efflux family protein
JTM80_RS13090	COG1376	ErfK ybiS ycfS ynhG family protein
JTM80_RS13095	COG2326	polyphosphate kinase activity
JTM80_RS13100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JTM80_RS13100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JTM80_RS13105	COG1649	PFAM Uncharacterised BCR, COG1649
JTM80_RS13110	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JTM80_RS13115	COG1131	(ABC) transporter
JTM80_RS13120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JTM80_RS13130	COG1850	ribulose-bisphosphate carboxylase activity
JTM80_RS13140	COG4451	ribulose bisphosphate carboxylase, small
JTM80_RS13150	COG0463	Glycosyl transferase, family 2
JTM80_RS13190	COG1088	dTDP-glucose 4,6-dehydratase activity
JTM80_RS13205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS13210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JTM80_RS13215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JTM80_RS13215	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JTM80_RS13225	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JTM80_RS13235	COG4251	negative regulation of phosphorylation
JTM80_RS13320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JTM80_RS13380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTM80_RS13385	COG0783	Belongs to the Dps family
JTM80_RS13400	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS13410	COG5554	nitrogen fixation
JTM80_RS13415	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS13420	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
JTM80_RS13425	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JTM80_RS13435	COG1104	cysteine desulfurase activity
JTM80_RS13450	COG1045	serine acetyltransferase
JTM80_RS13460	COG5420	small protein containing a coiled-coil domain
JTM80_RS13470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JTM80_RS13475	COG0316	Belongs to the HesB IscA family
JTM80_RS13490	COG0716	FMN binding
JTM80_RS13500	COG0500	methyltransferase
JTM80_RS13525	COG0446	pyridine nucleotide-disulphide oxidoreductase
JTM80_RS13540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JTM80_RS13545	COG0730	response to heat
JTM80_RS13550	COG1271	oxidase subunit
JTM80_RS13560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTM80_RS13565	COG0789	Transcriptional regulator
JTM80_RS13570	COG3385	transposase activity
JTM80_RS13590	COG0731	radical SAM domain protein
JTM80_RS13610	COG0446	pyridine nucleotide-disulphide oxidoreductase
JTM80_RS13645	COG0446	pyridine nucleotide-disulphide oxidoreductase
JTM80_RS13690	COG3385	transposase activity
JTM80_RS13705	COG3128	pkhd-type hydroxylase
JTM80_RS13715	COG5002	protein histidine kinase activity
JTM80_RS13725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTM80_RS13735	COG0686	Belongs to the AlaDH PNT family
JTM80_RS13740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JTM80_RS13755	COG0617	tRNA 3'-terminal CCA addition
JTM80_RS13765	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS13765	COG0515	serine threonine protein kinase
JTM80_RS13780	COG3852	Histidine kinase
JTM80_RS13830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JTM80_RS13835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JTM80_RS13840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JTM80_RS13870	COG0039	L-malate dehydrogenase activity
JTM80_RS13955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JTM80_RS13965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JTM80_RS13990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JTM80_RS13995	COG0501	Belongs to the peptidase M48B family
JTM80_RS14000	COG1522	sequence-specific DNA binding
JTM80_RS14010	COG4942	peptidase
JTM80_RS14015	COG0513	Belongs to the DEAD box helicase family
JTM80_RS14020	COG0640	Transcriptional regulator
JTM80_RS14025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS14030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JTM80_RS14040	COG0798	PFAM Bile acid sodium symporter
JTM80_RS14050	COG0495	leucyl-tRNA aminoacylation
JTM80_RS14055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JTM80_RS14060	COG4581	dead DEAH box helicase
JTM80_RS14065	COG5001	Diguanylate cyclase
JTM80_RS14105	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
JTM80_RS14110	COG0719	Fe-S assembly protein
JTM80_RS14120	COG0396	ATPase activity
JTM80_RS14125	COG0719	Fe-S assembly protein
JTM80_RS14130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JTM80_RS14135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JTM80_RS14140	COG1408	metallophosphoesterase
JTM80_RS14145	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JTM80_RS14150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JTM80_RS14150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JTM80_RS14165	COG0432	Pfam Uncharacterised protein family UPF0047
JTM80_RS14175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JTM80_RS14185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JTM80_RS14190	COG3932	Exopolysaccharide synthesis, ExoD
JTM80_RS14205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JTM80_RS14210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JTM80_RS14220	COG0450	alkyl hydroperoxide reductase
JTM80_RS14230	COG3001	Fructosamine kinase
JTM80_RS14235	COG0612	Peptidase, M16
JTM80_RS14265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JTM80_RS14270	COG0860	N-Acetylmuramoyl-L-alanine amidase
JTM80_RS14275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JTM80_RS14280	COG0181	hydroxymethylbilane synthase activity
JTM80_RS14290	COG0297	glycogen (starch) synthase activity
JTM80_RS14310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JTM80_RS14320	COG0745	RESPONSE REGULATOR receiver
JTM80_RS14325	COG5002	protein histidine kinase activity
JTM80_RS14340	COG0180	Tryptophanyl-tRNA synthetase
JTM80_RS14355	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JTM80_RS14395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JTM80_RS14400	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JTM80_RS14405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JTM80_RS14425	COG3629	intracellular signal transduction
JTM80_RS14425	COG3903	Transcriptional regulator
JTM80_RS14440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JTM80_RS14445	COG0581	inorganic phosphate transmembrane transporter activity
JTM80_RS14450	COG0573	inorganic phosphate transmembrane transporter activity
JTM80_RS14455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS14465	COG0300	oxidoreductase activity
JTM80_RS14465	COG3000	fatty acid hydroxylase
JTM80_RS14480	COG5002	protein histidine kinase activity
JTM80_RS14500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JTM80_RS14500	COG0189	ligase activity
JTM80_RS14505	COG4242	Belongs to the peptidase S51 family
JTM80_RS14510	COG0336	Belongs to the RNA methyltransferase TrmD family
JTM80_RS14525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JTM80_RS14530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTM80_RS14545	COG4191	Histidine kinase
JTM80_RS14560	COG1799	cell septum assembly
JTM80_RS14565	COG0824	Thioesterase
JTM80_RS14575	COG0469	pyruvate kinase activity
JTM80_RS14580	COG0588	phosphoglycerate mutase activity
JTM80_RS14585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JTM80_RS14590	COG0033	Phosphoglucomutase
JTM80_RS14610	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JTM80_RS14615	COG4585	Histidine kinase
JTM80_RS14620	COG2197	response regulator
JTM80_RS14635	COG1845	cytochrome c oxidase, subunit III
JTM80_RS14640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JTM80_RS14645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JTM80_RS14675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JTM80_RS14695	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JTM80_RS14705	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS14705	COG0515	serine threonine protein kinase
JTM80_RS14715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTM80_RS14730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JTM80_RS14740	COG2267	carboxylic ester hydrolase activity
JTM80_RS14745	COG5002	protein histidine kinase activity
JTM80_RS14765	COG0515	serine threonine protein kinase
JTM80_RS14765	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS14775	COG1132	(ABC) transporter
JTM80_RS14805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JTM80_RS14835	COG5002	protein histidine kinase activity
JTM80_RS14900	COG1468	defense response to virus
JTM80_RS14900	COG1518	maintenance of DNA repeat elements
JTM80_RS14935	COG0577	efflux transmembrane transporter activity
JTM80_RS14945	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JTM80_RS15005	COG3852	Histidine kinase
JTM80_RS15020	COG1191	sigma factor activity
JTM80_RS15025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JTM80_RS15035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JTM80_RS15045	COG0023	Translation Initiation Factor
JTM80_RS15055	COG0133	tryptophan synthase activity
JTM80_RS15060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JTM80_RS15115	COG0415	Belongs to the DNA photolyase family
JTM80_RS15165	COG2814	Major facilitator Superfamily
JTM80_RS15185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JTM80_RS15190	COG1546	Belongs to the CinA family
JTM80_RS15190	COG1058	Belongs to the CinA family
JTM80_RS15215	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS15220	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS15235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JTM80_RS15245	COG1672	PFAM Archaeal ATPase
JTM80_RS15245	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
JTM80_RS15260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JTM80_RS15280	COG4251	negative regulation of phosphorylation
JTM80_RS15290	COG0631	protein serine/threonine phosphatase activity
JTM80_RS15295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JTM80_RS15300	COG3937	granule-associated protein
JTM80_RS15305	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JTM80_RS15310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JTM80_RS15325	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS15325	COG0297	glycogen (starch) synthase activity
JTM80_RS15335	COG0746	molybdenum cofactor guanylyltransferase activity
JTM80_RS15365	COG0134	indole-3-glycerol-phosphate synthase activity
JTM80_RS15370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JTM80_RS15380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JTM80_RS15390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JTM80_RS15395	COG0483	inositol monophosphate 1-phosphatase activity
JTM80_RS15405	COG0745	RESPONSE REGULATOR receiver
JTM80_RS15410	COG2010	Cytochrome c
JTM80_RS15425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JTM80_RS15430	COG3842	ATPase activity
JTM80_RS15450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JTM80_RS15455	COG0488	(ABC) transporter
JTM80_RS15470	COG1372	Participates in initiation and elongation during chromosome replication
JTM80_RS15470	COG0305	Participates in initiation and elongation during chromosome replication
JTM80_RS15475	COG0359	binds to the 23S rRNA
JTM80_RS15480	COG0752	glycyl-tRNA synthetase alpha subunit
JTM80_RS15485	COG0514	ATP-dependent DNA helicase (RecQ)
JTM80_RS15500	COG1012	belongs to the aldehyde dehydrogenase family
JTM80_RS15505	COG2072	flavoprotein involved in K transport
JTM80_RS15535	COG2144	transferase activity, transferring acyl groups
JTM80_RS15555	COG1372	Participates in initiation and elongation during chromosome replication
JTM80_RS15555	COG0187	DNA topoisomerase II activity
JTM80_RS15560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JTM80_RS15570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JTM80_RS15575	COG0613	PHP domain protein
JTM80_RS15585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JTM80_RS15600	COG0681	Belongs to the peptidase S26 family
JTM80_RS15615	COG3608	succinylglutamate desuccinylase aspartoacylase
JTM80_RS15620	COG2385	sporulation resulting in formation of a cellular spore
JTM80_RS15630	COG1309	transcriptional regulator
JTM80_RS15645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JTM80_RS15655	COG0066	3-isopropylmalate dehydratase activity
JTM80_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS15670	COG3654	unkown
JTM80_RS15680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JTM80_RS15725	COG0668	transmembrane transport
JTM80_RS15730	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS15745	COG2255	four-way junction helicase activity
JTM80_RS15755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JTM80_RS15770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JTM80_RS15790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JTM80_RS15810	COG0697	spore germination
JTM80_RS15815	COG3237	CsbD-like
JTM80_RS15865	COG1295	ribonuclease BN
JTM80_RS15870	COG3659	wide pore channel activity
JTM80_RS15875	COG2233	PERMEase
JTM80_RS15890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JTM80_RS15895	COG2205	protein histidine kinase activity
JTM80_RS15905	COG0402	S-adenosylhomocysteine deaminase activity
JTM80_RS15910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JTM80_RS15915	COG0824	Thioesterase
JTM80_RS15920	COG0589	response to stress
JTM80_RS15950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JTM80_RS15970	COG0335	large ribosomal subunit rRNA binding
JTM80_RS15990	COG5000	phosphorelay sensor kinase activity
JTM80_RS15990	COG5002	protein histidine kinase activity
JTM80_RS16015	COG0484	heat shock protein binding
JTM80_RS16020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JTM80_RS16050	COG1732	Glycine betaine
JTM80_RS16125	COG3385	transposase activity
JTM80_RS16130	COG0556	nucleotide-excision repair
JTM80_RS16155	COG5002	protein histidine kinase activity
JTM80_RS16160	COG0745	RESPONSE REGULATOR receiver
JTM80_RS16195	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JTM80_RS16200	COG1175	transmembrane transport
JTM80_RS16255	COG0277	FAD linked oxidase domain protein
JTM80_RS16300	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS16305	COG0515	serine threonine protein kinase
JTM80_RS16335	COG0285	dihydrofolate synthase activity
JTM80_RS16340	COG4178	(ABC) transporter
JTM80_RS16345	COG0288	reversible hydration of carbon dioxide
JTM80_RS16370	COG0515	serine threonine protein kinase
JTM80_RS16370	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS16375	COG0542	response to heat
JTM80_RS16390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JTM80_RS16395	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS16405	COG3956	TIGRFAM MazG family protein
JTM80_RS16440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JTM80_RS16450	COG0612	Peptidase, M16
JTM80_RS16480	COG0792	nuclease activity
JTM80_RS16505	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
JTM80_RS16535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JTM80_RS16545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JTM80_RS16550	COG4221	oxidoreductase activity
JTM80_RS16575	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
JTM80_RS16590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JTM80_RS16600	COG0667	Aldo Keto reductase
JTM80_RS16605	COG2234	aminopeptidase activity
JTM80_RS16610	COG0714	Associated with various cellular activities
JTM80_RS16630	COG0837	glucose binding
JTM80_RS16635	COG0489	protein tyrosine kinase activity
JTM80_RS16640	COG1596	polysaccharide export
JTM80_RS16675	COG1045	serine acetyltransferase
JTM80_RS16680	COG1132	(ABC) transporter
JTM80_RS16690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JTM80_RS16695	COG1007	ATP synthesis coupled electron transport
JTM80_RS16710	COG0799	negative regulation of ribosome biogenesis
JTM80_RS16715	COG1713	HD superfamily hydrolase involved in NAD metabolism
JTM80_RS16720	COG0297	glycogen (starch) synthase activity
JTM80_RS16725	COG1254	Belongs to the acylphosphatase family
JTM80_RS16730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JTM80_RS16735	COG0459	protein refolding
JTM80_RS16745	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS16750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JTM80_RS16755	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JTM80_RS16760	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
JTM80_RS16765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JTM80_RS16765	COG4451	ribulose bisphosphate carboxylase, small
JTM80_RS16775	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
JTM80_RS16790	COG0631	protein serine/threonine phosphatase activity
JTM80_RS16795	COG1187	pseudouridine synthase activity
JTM80_RS16820	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JTM80_RS16830	COG0038	chloride channel
JTM80_RS16845	COG3385	transposase activity
JTM80_RS16870	COG0501	Belongs to the peptidase M48B family
JTM80_RS16875	COG2954	triphosphatase activity
JTM80_RS16905	COG4948	Mandelate Racemase Muconate Lactonizing
JTM80_RS16910	COG0482	sulfurtransferase activity
JTM80_RS16915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JTM80_RS16920	COG0859	PFAM glycosyl transferase family 9
JTM80_RS16925	COG0625	glutathione transferase activity
JTM80_RS16930	COG0789	Transcriptional regulator
JTM80_RS16985	COG0668	transmembrane transport
JTM80_RS17005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JTM80_RS17020	COG0174	glutamine synthetase
JTM80_RS17045	COG0352	thiamine-phosphate diphosphorylase activity
JTM80_RS17055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JTM80_RS17090	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JTM80_RS17100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JTM80_RS17145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JTM80_RS17150	COG0601	transmembrane transport
JTM80_RS17160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JTM80_RS17175	COG0793	Belongs to the peptidase S41A family
JTM80_RS17180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JTM80_RS17195	COG0386	Belongs to the glutathione peroxidase family
JTM80_RS17200	COG0528	UMP kinase activity
JTM80_RS17205	COG0233	cytoplasmic translational termination
JTM80_RS17210	COG0492	ferredoxin-NADP+ reductase activity
JTM80_RS17215	COG5002	protein histidine kinase activity
JTM80_RS17220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTM80_RS17225	COG2154	pterin-4-alpha-carbinolamine dehydratase
JTM80_RS17235	COG1176	ABC-type spermidine putrescine transport system, permease component I
JTM80_RS17245	COG1116	anion transmembrane transporter activity
JTM80_RS17250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JTM80_RS17265	COG1615	UPF0182 protein
JTM80_RS17280	COG4968	Prepilin-type N-terminal cleavage methylation domain
JTM80_RS17285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JTM80_RS17300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JTM80_RS17310	COG1492	cobalamin metabolic process
JTM80_RS17340	COG0582	viral genome integration into host DNA
JTM80_RS17345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JTM80_RS17355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JTM80_RS17385	COG3224	Antibiotic biosynthesis monooxygenase
JTM80_RS17395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JTM80_RS17405	COG1316	TRANSCRIPTIONal
JTM80_RS17425	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JTM80_RS17430	COG0058	SHG alpha-glucan phosphorylase activity
JTM80_RS17490	COG1595	DNA-templated transcription, initiation
JTM80_RS17495	COG1054	Belongs to the UPF0176 family
JTM80_RS17505	COG3903	Transcriptional regulator
JTM80_RS17505	COG2319	Wd-40 repeat
JTM80_RS17510	COG1744	ABC transporter substrate-binding protein PnrA-like
JTM80_RS17515	COG4603	Belongs to the binding-protein-dependent transport system permease family
JTM80_RS17520	COG1079	Belongs to the binding-protein-dependent transport system permease family
JTM80_RS17530	COG3845	ABC transporter
JTM80_RS17540	COG0017	Asparaginyl-tRNA synthetase
JTM80_RS17595	COG0402	S-adenosylhomocysteine deaminase activity
JTM80_RS17600	COG2177	Part of the ABC transporter FtsEX involved in
JTM80_RS17645	COG0316	Belongs to the HesB IscA family
JTM80_RS17660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JTM80_RS17675	COG2239	Acts as a magnesium transporter
JTM80_RS17680	COG1006	Multisubunit Na H antiporter MnhC subunit
JTM80_RS17685	COG0651	ATP synthesis coupled electron transport
JTM80_RS17765	COG0154	amidase activity
JTM80_RS17770	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JTM80_RS17785	COG0659	secondary active sulfate transmembrane transporter activity
JTM80_RS17790	COG0284	orotidine-5'-phosphate decarboxylase activity
JTM80_RS17825	COG0412	Dienelactone hydrolase
JTM80_RS17840	COG2831	hemolysin activation secretion protein
JTM80_RS17850	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JTM80_RS17860	COG1496	oxidoreductase activity
JTM80_RS17865	COG4251	negative regulation of phosphorylation
JTM80_RS17875	COG1032	radical SAM domain protein
JTM80_RS17885	COG0124	histidyl-tRNA synthetase
JTM80_RS17895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JTM80_RS17915	COG0765	amino acid transport
JTM80_RS17935	COG1331	Highly conserved protein containing a thioredoxin domain
JTM80_RS17940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JTM80_RS17945	COG0776	regulation of translation
JTM80_RS18030	COG0783	Belongs to the Dps family
JTM80_RS18035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JTM80_RS18045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JTM80_RS18055	COG2197	response regulator
JTM80_RS18060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JTM80_RS18110	COG0668	transmembrane transport
JTM80_RS18155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JTM80_RS18160	COG0489	protein tyrosine kinase activity
JTM80_RS18185	COG0475	glutathione-regulated potassium exporter activity
JTM80_RS18210	COG1653	transport
JTM80_RS18235	COG1230	cation diffusion facilitator family transporter
JTM80_RS18240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JTM80_RS18265	COG0358	DNA primase activity
JTM80_RS18275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JTM80_RS18280	COG0515	serine threonine protein kinase
JTM80_RS18280	COG1357	PFAM Pentapeptide repeats (8 copies)
JTM80_RS18295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JTM80_RS18325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JTM80_RS18330	COG2204	response regulator
JTM80_RS18340	COG0612	Peptidase, M16
JTM80_RS18345	COG1126	abc transporter atp-binding protein
JTM80_RS18360	COG1090	epimerase
JTM80_RS18380	COG1201	RNA secondary structure unwinding
JTM80_RS18390	COG3179	chitinase
JTM80_RS18395	COG0174	glutamine synthetase
JTM80_RS18400	COG1012	belongs to the aldehyde dehydrogenase family
JTM80_RS18405	COG3385	transposase activity
JTM80_RS18430	COG3385	transposase activity
JTM80_RS18450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JTM80_RS18455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JTM80_RS18455	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JTM80_RS18480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JTM80_RS18500	COG5001	Diguanylate cyclase
JTM80_RS18510	COG0442	prolyl-tRNA aminoacylation
JTM80_RS18535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JTM80_RS18535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JTM80_RS18540	COG2205	protein histidine kinase activity
JTM80_RS18540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JTM80_RS18545	COG2197	response regulator
JTM80_RS18560	COG0475	glutathione-regulated potassium exporter activity
JTM80_RS18560	COG0589	response to stress
JTM80_RS18565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JTM80_RS18570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JTM80_RS18580	COG0514	ATP-dependent DNA helicase (RecQ)
JTM80_RS18590	COG1741	Belongs to the pirin family
JTM80_RS18600	COG1733	regulation of RNA biosynthetic process
JTM80_RS18625	COG3903	Transcriptional regulator
JTM80_RS18625	COG3629	intracellular signal transduction
JTM80_RS18635	COG4636	protein conserved in cyanobacteria
JTM80_RS18640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JTM80_RS18660	COG1131	(ABC) transporter
JTM80_RS18665	COG3604	Transcriptional regulator
JTM80_RS18670	COG0640	Transcriptional regulator
JTM80_RS18705	COG3321	synthase
JTM80_RS18705	COG0604	alcohol dehydrogenase
JTM80_RS18710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTM80_RS18715	COG3321	synthase
JTM80_RS18715	COG0604	alcohol dehydrogenase
JTM80_RS18725	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS18725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JTM80_RS18745	COG1073	alpha beta
JTM80_RS18750	COG0473	3-isopropylmalate dehydrogenase activity
JTM80_RS18755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JTM80_RS18760	COG2091	lysine biosynthetic process via aminoadipic acid
JTM80_RS18770	COG0725	ABC transporter, periplasmic molybdate-binding protein
JTM80_RS18775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JTM80_RS18780	COG4149	molybdate abc transporter
JTM80_RS18825	COG1214	PFAM Peptidase M22, glycoprotease
JTM80_RS18845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JTM80_RS18850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JTM80_RS18855	COG0542	response to heat
JTM80_RS18860	COG0456	acetyltransferase
JTM80_RS18865	COG0019	diaminopimelate decarboxylase activity
JTM80_RS18870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JTM80_RS18875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JTM80_RS18900	COG0196	riboflavin kinase activity
JTM80_RS18905	COG1234	tRNA 3'-trailer cleavage
JTM80_RS18910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JTM80_RS18915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JTM80_RS18925	COG5001	Diguanylate cyclase
JTM80_RS18925	COG1716	ATPase activity
JTM80_RS18950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JTM80_RS18950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JTM80_RS18965	COG0318	PFAM AMP-dependent synthetase and ligase
JTM80_RS18965	COG0204	Acyl-transferase
JTM80_RS18970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JTM80_RS18975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JTM80_RS18980	COG0416	fatty acid biosynthetic process
JTM80_RS18985	COG0745	RESPONSE REGULATOR receiver
JTM80_RS18990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JTM80_RS19005	COG0456	acetyltransferase
JTM80_RS19025	COG0745	RESPONSE REGULATOR receiver
JTM80_RS19030	COG2205	protein histidine kinase activity
JTM80_RS19030	COG0784	Response regulator, receiver
JTM80_RS19030	COG5002	protein histidine kinase activity
JTM80_RS19040	COG1994	Peptidase M50
JTM80_RS19065	COG0123	including yeast histone deacetylase and acetoin utilization protein
JTM80_RS19080	COG1131	(ABC) transporter
JTM80_RS19090	COG0473	3-isopropylmalate dehydrogenase activity
JTM80_RS19095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JTM80_RS19130	COG1696	Membrane protein involved in D-alanine export
JTM80_RS19135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JTM80_RS19140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JTM80_RS19150	COG2226	methyltransferase
JTM80_RS19175	COG0717	Belongs to the dCTP deaminase family
JTM80_RS19185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JTM80_RS19195	COG1217	gtp-binding protein TYPA
JTM80_RS19230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JTM80_RS19235	COG0802	atpase or kinase
JTM80_RS19255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JTM80_RS19275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JTM80_RS19280	COG0596	Alpha beta hydrolase
JTM80_RS19310	COG3119	arylsulfatase activity
JTM80_RS19360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JTM80_RS19380	COG4636	protein conserved in cyanobacteria
JTM80_RS19385	COG5002	protein histidine kinase activity
JTM80_RS19390	COG0596	Alpha beta hydrolase
JTM80_RS19400	COG0018	arginyl-trna synthetase
JTM80_RS19415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JTM80_RS19430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JTM80_RS19435	COG2202	Pas domain
JTM80_RS19435	COG2205	protein histidine kinase activity
JTM80_RS19465	COG0347	Belongs to the P(II) protein family
JTM80_RS19470	COG0095	Lipoate-protein ligase
JTM80_RS19495	COG3852	Histidine kinase
JTM80_RS19500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JTM80_RS19510	COG0312	modulator of DNA gyrase
JTM80_RS19525	COG0242	peptide deformylase activity
JTM80_RS19550	COG0113	porphobilinogen synthase activity
JTM80_RS19595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JTM80_RS19615	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JTM80_RS19620	COG1895	HEPN domain
JTM80_RS19625	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS19645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JTM80_RS19655	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS19700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JTM80_RS19705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JTM80_RS19710	COG4249	Peptidase C14 caspase catalytic subunit p20
JTM80_RS19710	COG2319	Wd-40 repeat
JTM80_RS19730	COG3128	pkhd-type hydroxylase
JTM80_RS19755	COG5002	protein histidine kinase activity
JTM80_RS19760	COG1836	PFAM Integral membrane protein DUF92
JTM80_RS19785	COG0492	ferredoxin-NADP+ reductase activity
JTM80_RS19790	COG0590	tRNA wobble adenosine to inosine editing
JTM80_RS19795	COG2205	protein histidine kinase activity
JTM80_RS19800	COG0784	Response regulator, receiver
JTM80_RS19805	COG3659	wide pore channel activity
JTM80_RS19810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JTM80_RS19855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JTM80_RS19895	COG4447	cellulose binding
JTM80_RS19900	COG1773	rubredoxin
JTM80_RS19905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JTM80_RS19910	COG1268	BioY protein
JTM80_RS19915	COG1234	tRNA 3'-trailer cleavage
JTM80_RS19920	COG2239	Acts as a magnesium transporter
JTM80_RS19925	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JTM80_RS19945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JTM80_RS19950	COG3118	belongs to the thioredoxin family
JTM80_RS19970	COG0714	Associated with various cellular activities
JTM80_RS19985	COG0745	RESPONSE REGULATOR receiver
JTM80_RS19990	COG0673	inositol 2-dehydrogenase activity
JTM80_RS20005	COG1649	PFAM Uncharacterised BCR, COG1649
JTM80_RS20020	COG2274	protein secretion by the type I secretion system
JTM80_RS20060	COG3443	Belongs to the bacterial solute-binding protein 9 family
JTM80_RS20060	COG0803	Belongs to the bacterial solute-binding protein 9 family
JTM80_RS20065	COG3385	transposase activity
JTM80_RS20075	COG3385	transposase activity
JTM80_RS20080	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JTM80_RS20085	COG0716	FMN binding
JTM80_RS20100	COG0589	response to stress
JTM80_RS20110	COG3385	transposase activity
JTM80_RS20155	COG0436	Aminotransferase
JTM80_RS20205	COG2319	Wd-40 repeat
JTM80_RS20205	COG1672	PFAM Archaeal ATPase
JTM80_RS20215	COG5001	Diguanylate cyclase
JTM80_RS20215	COG2203	Gaf domain
JTM80_RS20215	COG3706	GGDEF domain
JTM80_RS20215	COG4251	negative regulation of phosphorylation
JTM80_RS20225	COG0508	dehydrogenase complex catalyzes the overall conversion of
JTM80_RS20225	COG0022	dehydrogenase e1 component
JTM80_RS20255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JTM80_RS20265	COG0640	Transcriptional regulator
JTM80_RS20275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JTM80_RS20290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JTM80_RS20330	COG0494	nUDIX hydrolase
JTM80_RS20335	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JTM80_RS20345	COG0406	alpha-ribazole phosphatase activity
JTM80_RS20400	COG0529	Catalyzes the synthesis of activated sulfate
JTM80_RS20405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS20410	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JTM80_RS20430	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20435	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20445	COG1489	DNA binding
JTM80_RS20465	COG2346	COG2346, Truncated hemoglobins
JTM80_RS20505	COG1834	amidinotransferase
JTM80_RS20510	COG2267	carboxylic ester hydrolase activity
JTM80_RS20525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JTM80_RS20530	COG0673	inositol 2-dehydrogenase activity
JTM80_RS20545	COG0460	homoserine dehydrogenase
JTM80_RS20555	COG1672	PFAM Archaeal ATPase
JTM80_RS20555	COG2319	Wd-40 repeat
JTM80_RS20565	COG2198	Histidine kinase
JTM80_RS20565	COG5002	protein histidine kinase activity
JTM80_RS20565	COG0784	Response regulator, receiver
JTM80_RS20590	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
JTM80_RS20595	COG4251	negative regulation of phosphorylation
JTM80_RS20605	COG2205	protein histidine kinase activity
JTM80_RS20615	COG0455	bacterial-type flagellum organization
JTM80_RS20620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JTM80_RS20640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JTM80_RS20640	COG2022	thiamine diphosphate biosynthetic process
JTM80_RS20650	COG0739	heme binding
JTM80_RS20660	COG1662	PFAM IS1 transposase
JTM80_RS20665	COG0237	dephospho-CoA kinase activity
JTM80_RS20670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JTM80_RS20675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JTM80_RS20685	COG4172	Belongs to the ABC transporter superfamily
JTM80_RS20720	COG0489	protein tyrosine kinase activity
JTM80_RS20725	COG1132	(ABC) transporter
JTM80_RS20745	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20755	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20760	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20770	COG0438	transferase activity, transferring glycosyl groups
JTM80_RS20800	COG4572	Cation transport regulator
JTM80_RS20805	COG0484	heat shock protein binding
JTM80_RS20810	COG0789	Transcriptional regulator
JTM80_RS20860	COG0768	penicillin binding
JTM80_RS20895	COG1136	(ABC) transporter
JTM80_RS20905	COG1472	Belongs to the glycosyl hydrolase 3 family
JTM80_RS20910	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JTM80_RS20980	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JTM80_RS20995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JTM80_RS21010	COG2723	6-phospho-beta-galactosidase activity
JTM80_RS21015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JTM80_RS21025	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JTM80_RS21030	COG2094	Belongs to the DNA glycosylase MPG family
JTM80_RS21070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JTM80_RS21130	COG1032	radical SAM domain protein
JTM80_RS21175	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JTM80_RS21195	COG2183	response to ionizing radiation
JTM80_RS21205	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JTM80_RS21215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JTM80_RS21235	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JTM80_RS21240	COG0189	ligase activity
JTM80_RS21255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JTM80_RS21265	COG0402	S-adenosylhomocysteine deaminase activity
JTM80_RS21280	COG1012	belongs to the aldehyde dehydrogenase family
JTM80_RS21285	COG0583	DNA-binding transcription factor activity
JTM80_RS21290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JTM80_RS21300	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JTM80_RS21320	COG0822	iron-sulfur transferase activity
JTM80_RS21325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JTM80_RS21350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS21355	COG1528	Iron-storage protein
JTM80_RS21365	COG0318	PFAM AMP-dependent synthetase and ligase
JTM80_RS21380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JTM80_RS21390	COG0330	HflC and HflK could
JTM80_RS21420	COG2066	Belongs to the glutaminase family
JTM80_RS21425	COG0489	protein tyrosine kinase activity
JTM80_RS21440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JTM80_RS21455	COG0045	succinate-CoA ligase (ADP-forming) activity
JTM80_RS21475	COG0151	Belongs to the GarS family
JTM80_RS21490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JTM80_RS21515	COG0402	S-adenosylhomocysteine deaminase activity
JTM80_RS21525	COG0228	four-way junction DNA binding
JTM80_RS21535	COG1702	phosphate starvation-inducible protein PhoH
JTM80_RS21550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JTM80_RS21555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JTM80_RS21560	COG4956	integral membrane protein (PIN domain superfamily)
JTM80_RS21565	COG2226	methyltransferase
JTM80_RS21570	COG0431	NADPH-dependent FMN reductase
JTM80_RS21575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JTM80_RS21585	COG0583	DNA-binding transcription factor activity
JTM80_RS21590	COG0515	serine threonine protein kinase
JTM80_RS21600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JTM80_RS21610	COG0659	secondary active sulfate transmembrane transporter activity
JTM80_RS21615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JTM80_RS21630	COG0534	Mate efflux family protein
JTM80_RS21635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JTM80_RS21650	COG0511	ligase activity, forming carbon-carbon bonds
JTM80_RS21655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JTM80_RS21660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JTM80_RS21670	COG0159	tryptophan synthase activity
JTM80_RS21680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JTM80_RS21690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JTM80_RS21700	COG0741	lytic transglycosylase activity
JTM80_RS21700	COG0739	heme binding
JTM80_RS21700	COG1196	nuclear chromosome segregation
JTM80_RS21705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JTM80_RS21710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JTM80_RS21720	COG4106	trans-aconitate 2-methyltransferase activity
JTM80_RS21730	COG0156	8-amino-7-oxononanoate synthase activity
JTM80_RS21740	COG0745	RESPONSE REGULATOR receiver
JTM80_RS21750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JTM80_RS21765	COG2367	Beta-lactamase
JTM80_RS21770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JTM80_RS21775	COG0739	heme binding
JTM80_RS21805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JTM80_RS21815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JTM80_RS21815	COG0140	phosphoribosyl-ATP diphosphatase activity
JTM80_RS21850	COG1132	(ABC) transporter
JTM80_RS21875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JTM80_RS21885	COG2203	Gaf domain
JTM80_RS21885	COG3706	GGDEF domain
JTM80_RS21885	COG4251	negative regulation of phosphorylation
JTM80_RS21885	COG5001	Diguanylate cyclase
JTM80_RS21890	COG0784	Response regulator, receiver
JTM80_RS21890	COG2205	protein histidine kinase activity
JTM80_RS21895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JTM80_RS21900	COG5001	Diguanylate cyclase
JTM80_RS21900	COG3300	MHYT domain
JTM80_RS21910	COG0003	Pfam Anion-transporting ATPase
JTM80_RS21915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JTM80_RS21920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JTM80_RS21925	COG2226	methyltransferase
JTM80_RS21950	COG0592	DNA-directed DNA polymerase activity
JTM80_RS21960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JTM80_RS21965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JTM80_RS21980	COG0583	DNA-binding transcription factor activity
JTM80_RS21995	COG0515	serine threonine protein kinase
JTM80_RS22020	COG0339	signal peptide processing
JTM80_RS22040	COG1215	transferase activity, transferring glycosyl groups
JTM80_RS22045	COG0463	Glycosyl transferase, family 2
JTM80_RS22055	COG0489	protein tyrosine kinase activity
JTM80_RS22095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JTM80_RS22100	COG4242	Belongs to the peptidase S51 family
JTM80_RS22135	COG2124	cytochrome p450
JTM80_RS22165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JTM80_RS22190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JTM80_RS22225	COG0189	ligase activity
JTM80_RS22225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JTM80_RS22235	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JTM80_RS22275	COG2048	Heterodisulfide reductase, subunit B
JTM80_RS22290	COG1473	amidohydrolase
JTM80_RS22295	COG1116	anion transmembrane transporter activity
JTM80_RS22320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JTM80_RS22325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JTM80_RS22345	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JTM80_RS22350	COG0811	peptide transport
JTM80_RS22360	COG0848	biopolymer transport protein
JTM80_RS22375	COG0384	phenazine biosynthesis protein PhzF
JTM80_RS22380	COG0586	Pfam SNARE associated Golgi protein
JTM80_RS22385	COG1073	alpha beta
JTM80_RS22400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JTM80_RS22405	COG0667	Aldo Keto reductase
JTM80_RS22410	COG2884	Cell division ATP-binding protein ftsE
JTM80_RS22445	COG1028	Short-chain dehydrogenase reductase Sdr
JTM80_RS22470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JTM80_RS22480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity