locus-tag	class	description
H9L17_RS00010	COG0077	Prephenate dehydratase
H9L17_RS00010	COG1605	Chorismate mutase
H9L17_RS00015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L17_RS00020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9L17_RS00045	COG1131	(ABC) transporter
H9L17_RS00050	COG1725	Transcriptional regulator
H9L17_RS00075	COG2900	Belongs to the SlyX family
H9L17_RS00085	COG0646	methionine synthase
H9L17_RS00085	COG1410	methionine synthase
H9L17_RS00100	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS00105	COG2902	Dehydrogenase
H9L17_RS00115	COG5002	protein histidine kinase activity
H9L17_RS00115	COG5001	Diguanylate cyclase
H9L17_RS00130	COG2925	Exonuclease
H9L17_RS00135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_RS00145	COG3844	kynureninase activity
H9L17_RS00160	COG1420	regulation of RNA biosynthetic process
H9L17_RS00165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9L17_RS00170	COG0443	Heat shock 70 kDa protein
H9L17_RS00175	COG0484	heat shock protein binding
H9L17_RS00180	COG1605	Chorismate mutase
H9L17_RS00180	COG0287	Prephenate dehydrogenase
H9L17_RS00190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9L17_RS00195	COG0505	Belongs to the CarA family
H9L17_RS00200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9L17_RS00205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_RS00215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9L17_RS00220	COG0671	phosphoesterase, PA-phosphatase related
H9L17_RS00230	COG3279	Response regulator of the LytR AlgR family
H9L17_RS00245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9L17_RS00255	COG2205	protein histidine kinase activity
H9L17_RS00255	COG2198	Histidine kinase
H9L17_RS00255	COG0784	Response regulator, receiver
H9L17_RS00260	COG1024	Enoyl-CoA hydratase
H9L17_RS00265	COG0318	PFAM AMP-dependent synthetase and ligase
H9L17_RS00280	COG3706	GGDEF domain
H9L17_RS00300	COG2409	Drug exporters of the RND superfamily
H9L17_RS00310	COG0745	RESPONSE REGULATOR receiver
H9L17_RS00320	COG0835	chemotaxis
H9L17_RS00325	COG1192	Involved in chromosome partitioning
H9L17_RS00330	COG1360	Flagellar Motor Protein
H9L17_RS00335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L17_RS00340	COG0643	Histidine kinase
H9L17_RS00340	COG0784	Response regulator, receiver
H9L17_RS00340	COG2198	Histidine kinase
H9L17_RS00345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H9L17_RS00370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9L17_RS00380	COG1684	flagellar biosynthetic protein fliR
H9L17_RS00385	COG1987	bacterial-type flagellum assembly
H9L17_RS00445	COG1677	Flagellar hook-basal body complex protein FliE
H9L17_RS00455	COG2201	protein-glutamate methylesterase activity
H9L17_RS00460	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9L17_RS00490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L17_RS00560	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9L17_RS00565	COG4786	Flagellar basal body rod
H9L17_RS00570	COG4787	bacterial-type flagellum-dependent cell motility
H9L17_RS00575	COG1749	Flagellar hook protein flgE
H9L17_RS00580	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9L17_RS00590	COG1815	bacterial-type flagellum-dependent cell motility
H9L17_RS00595	COG0784	Response regulator, receiver
H9L17_RS00595	COG0835	chemotaxis
H9L17_RS00620	COG5001	Diguanylate cyclase
H9L17_RS00620	COG3300	MHYT domain
H9L17_RS00695	COG0590	tRNA wobble adenosine to inosine editing
H9L17_RS00710	COG4974	Belongs to the 'phage' integrase family
H9L17_RS00725	COG1902	pentaerythritol trinitrate reductase activity
H9L17_RS00770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9L17_RS00775	COG2217	Heavy metal translocating P-type atpase
H9L17_RS00780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L17_RS00795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9L17_RS00800	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9L17_RS00825	COG0789	Transcriptional regulator
H9L17_RS00830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_RS00965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L17_RS01035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_RS01080	COG2217	Heavy metal translocating P-type atpase
H9L17_RS01085	COG2608	mercury ion transmembrane transporter activity
H9L17_RS01090	COG2132	Multicopper oxidase
H9L17_RS01115	COG0714	Associated with various cellular activities
H9L17_RS01145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_RS01150	COG2914	Belongs to the UPF0125 (RnfH) family
H9L17_RS01155	COG2867	negative regulation of translational initiation
H9L17_RS01160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9L17_RS01190	COG0668	transmembrane transport
H9L17_RS01195	COG2199	diguanylate cyclase activity
H9L17_RS01200	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H9L17_RS01215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_RS01215	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_RS01235	COG1160	GTP binding
H9L17_RS01240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_RS01260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9L17_RS01265	COG0105	UTP biosynthetic process
H9L17_RS01275	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_RS01275	COG1024	Enoyl-CoA hydratase
H9L17_RS01280	COG0183	Belongs to the thiolase family
H9L17_RS01285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9L17_RS01300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9L17_RS01310	COG0776	regulation of translation
H9L17_RS01320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9L17_RS01325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9L17_RS01335	COG2957	Belongs to the agmatine deiminase family
H9L17_RS01340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_RS01350	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L17_RS01350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9L17_RS01350	COG1042	CoA-binding domain protein
H9L17_RS01375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_RS01400	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9L17_RS01410	COG1183	phosphatidylcholine synthase activity
H9L17_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS01430	COG1064	alcohol dehydrogenase
H9L17_RS01480	COG0583	DNA-binding transcription factor activity
H9L17_RS01485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9L17_RS01490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9L17_RS01515	COG2850	peptidyl-arginine hydroxylation
H9L17_RS01525	COG0567	Dehydrogenase, E1 component
H9L17_RS01545	COG0604	alcohol dehydrogenase
H9L17_RS01560	COG0678	peroxiredoxin activity
H9L17_RS01565	COG4953	penicillin-binding protein 1C
H9L17_RS01585	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9L17_RS01595	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H9L17_RS01600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L17_RS01605	COG3115	cell septum assembly
H9L17_RS01620	COG2350	Protein conserved in bacteria
H9L17_RS01630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9L17_RS01635	COG1187	pseudouridine synthase activity
H9L17_RS01690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_RS01700	COG0436	Aminotransferase
H9L17_RS01740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_RS01760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L17_RS01775	COG0438	transferase activity, transferring glycosyl groups
H9L17_RS01780	COG0671	phosphoesterase, PA-phosphatase related
H9L17_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS01805	COG0288	reversible hydration of carbon dioxide
H9L17_RS01825	COG4774	siderophore transport
H9L17_RS01830	COG2382	esterase
H9L17_RS01855	COG1185	polyribonucleotide nucleotidyltransferase activity
H9L17_RS01860	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9L17_RS01880	COG0195	Participates in both transcription termination and antitermination
H9L17_RS01885	COG0779	Required for maturation of 30S ribosomal subunits
H9L17_RS01895	COG1007	ATP synthesis coupled electron transport
H9L17_RS01935	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H9L17_RS01940	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9L17_RS01945	COG0649	NAD binding
H9L17_RS01950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_RS01955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_RS01960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L17_RS01970	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_RS01970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_RS01975	COG2081	HI0933 family
H9L17_RS01995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L17_RS02005	COG0438	transferase activity, transferring glycosyl groups
H9L17_RS02040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9L17_RS02045	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9L17_RS02080	COG1596	polysaccharide export
H9L17_RS02090	COG0529	Catalyzes the synthesis of activated sulfate
H9L17_RS02090	COG2895	sulfate adenylyltransferase (ATP) activity
H9L17_RS02095	COG0175	sulfate reduction
H9L17_RS02100	COG0069	glutamate synthase activity
H9L17_RS02120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9L17_RS02125	COG0322	excinuclease ABC activity
H9L17_RS02130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9L17_RS02135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9L17_RS02140	COG1663	tetraacyldisaccharide 4'-kinase activity
H9L17_RS02145	COG1132	(ABC) transporter
H9L17_RS02155	COG0811	peptide transport
H9L17_RS02160	COG2333	competence protein COMEC
H9L17_RS02160	COG0658	competence protein
H9L17_RS02175	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L17_RS02195	COG1053	succinate dehydrogenase
H9L17_RS02200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H9L17_RS02230	COG0028	Belongs to the TPP enzyme family
H9L17_RS02235	COG0022	dehydrogenase e1 component
H9L17_RS02240	COG0625	glutathione transferase activity
H9L17_RS02250	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS02265	COG0084	hydrolase, TatD family'
H9L17_RS02270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9L17_RS02275	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H9L17_RS02295	COG2133	pyrroloquinoline quinone binding
H9L17_RS02315	COG0386	Belongs to the glutathione peroxidase family
H9L17_RS02320	COG0339	signal peptide processing
H9L17_RS02335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9L17_RS02345	COG1469	GTP cyclohydrolase I activity
H9L17_RS02360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L17_RS02365	COG0402	S-adenosylhomocysteine deaminase activity
H9L17_RS02375	COG1509	lysine 2,3-aminomutase activity
H9L17_RS02380	COG3300	MHYT domain
H9L17_RS02380	COG5001	Diguanylate cyclase
H9L17_RS02385	COG0501	Belongs to the peptidase M48B family
H9L17_RS02395	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS02420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9L17_RS02435	COG0582	viral genome integration into host DNA
H9L17_RS02505	COG3237	CsbD-like
H9L17_RS02510	COG0840	transmembrane signaling receptor activity
H9L17_RS02555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_RS02560	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
H9L17_RS02570	COG0019	diaminopimelate decarboxylase activity
H9L17_RS02585	COG4948	Mandelate Racemase Muconate Lactonizing
H9L17_RS02590	COG1737	Transcriptional regulator
H9L17_RS02600	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9L17_RS02610	COG0527	aspartate kinase activity
H9L17_RS02610	COG0460	homoserine dehydrogenase
H9L17_RS02620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9L17_RS02625	COG0590	tRNA wobble adenosine to inosine editing
H9L17_RS02660	COG1012	belongs to the aldehyde dehydrogenase family
H9L17_RS02675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9L17_RS02690	COG0515	serine threonine protein kinase
H9L17_RS02690	COG2815	serine threonine protein kinase
H9L17_RS02700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9L17_RS02705	COG1570	exodeoxyribonuclease VII activity
H9L17_RS02715	COG1595	DNA-templated transcription, initiation
H9L17_RS02725	COG1132	(ABC) transporter
H9L17_RS02755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9L17_RS02760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9L17_RS02765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9L17_RS02770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L17_RS02775	COG0617	tRNA 3'-terminal CCA addition
H9L17_RS02785	COG1201	RNA secondary structure unwinding
H9L17_RS02800	COG1187	pseudouridine synthase activity
H9L17_RS02810	COG0705	Rhomboid family
H9L17_RS02815	COG3104	oligopeptide transport
H9L17_RS02820	COG0625	glutathione transferase activity
H9L17_RS02850	COG0456	acetyltransferase
H9L17_RS02860	COG4774	siderophore transport
H9L17_RS02865	COG3128	pkhd-type hydroxylase
H9L17_RS02885	COG1477	protein flavinylation
H9L17_RS02890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9L17_RS02945	COG4969	Belongs to the N-Me-Phe pilin family
H9L17_RS02950	COG3275	phosphorelay sensor kinase activity
H9L17_RS02955	COG1611	Belongs to the LOG family
H9L17_RS02965	COG2095	MarC family integral membrane protein
H9L17_RS02970	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS02995	COG2835	tetraacyldisaccharide 4'-kinase activity
H9L17_RS03020	COG2969	positive regulation of protein catabolic process
H9L17_RS03025	COG0625	glutathione transferase activity
H9L17_RS03030	COG2857	Cytochrome c1
H9L17_RS03035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9L17_RS03040	COG0723	plastoquinol--plastocyanin reductase activity
H9L17_RS03045	COG0741	lytic transglycosylase activity
H9L17_RS03050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L17_RS03060	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H9L17_RS03065	COG0842	Transport permease protein
H9L17_RS03070	COG1131	(ABC) transporter
H9L17_RS03080	COG1309	transcriptional regulator
H9L17_RS03085	COG1702	phosphate starvation-inducible protein PhoH
H9L17_RS03090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L17_RS03095	COG4535	Mg2 and Co2 transporter CorC
H9L17_RS03115	COG1506	peptidase
H9L17_RS03115	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_RS03120	COG1297	OPT oligopeptide transporter protein
H9L17_RS03125	COG3104	oligopeptide transport
H9L17_RS03150	COG0306	phosphate transporter
H9L17_RS03160	COG1253	flavin adenine dinucleotide binding
H9L17_RS03185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L17_RS03190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L17_RS03195	COG1862	Preprotein translocase
H9L17_RS03200	COG0343	queuine tRNA-ribosyltransferase activity
H9L17_RS03210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9L17_RS03215	COG1522	sequence-specific DNA binding
H9L17_RS03220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L17_RS03230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L17_RS03235	COG0405	Gamma-glutamyltransferase
H9L17_RS03250	COG0742	ribosomal rna small subunit methyltransferase
H9L17_RS03255	COG0552	protein localization to endoplasmic reticulum
H9L17_RS03265	COG1194	a g-specific adenine glycosylase
H9L17_RS03270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H9L17_RS03290	COG4774	siderophore transport
H9L17_RS03380	COG0582	viral genome integration into host DNA
H9L17_RS03390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L17_RS03395	COG0149	triose-phosphate isomerase activity
H9L17_RS03415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L17_RS03430	COG0133	tryptophan synthase activity
H9L17_RS03435	COG0135	phosphoribosylanthranilate isomerase activity
H9L17_RS03445	COG0101	tRNA pseudouridine synthase activity
H9L17_RS03455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L17_RS03475	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L17_RS03480	COG1999	signal sequence binding
H9L17_RS03485	COG0688	phosphatidylethanolamine metabolic process
H9L17_RS03490	COG3401	FG-GAP repeat protein
H9L17_RS03505	COG0433	COG0433 Predicted ATPase
H9L17_RS03515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_RS03540	COG0717	Belongs to the dCTP deaminase family
H9L17_RS03545	COG0489	protein tyrosine kinase activity
H9L17_RS03550	COG4771	TonB-dependent receptor
H9L17_RS03560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_RS03560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_RS03570	COG2878	Part of a membrane complex involved in electron transport
H9L17_RS03590	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9L17_RS03595	COG0802	atpase or kinase
H9L17_RS03600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9L17_RS03600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9L17_RS03605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L17_RS03615	COG3654	unkown
H9L17_RS03630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L17_RS03635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_RS03660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9L17_RS03665	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H9L17_RS03675	COG0826	peptidase U32
H9L17_RS03680	COG0826	peptidase U32
H9L17_RS03685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9L17_RS03695	COG3154	lipid carrier protein
H9L17_RS03740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_RS03745	COG3278	Belongs to the heme-copper respiratory oxidase family
H9L17_RS03760	COG2010	Cytochrome c
H9L17_RS03820	COG3093	addiction module antidote protein HigA
H9L17_RS03825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L17_RS03830	COG1393	Belongs to the ArsC family
H9L17_RS03845	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H9L17_RS03850	COG0024	Methionine aminopeptidase
H9L17_RS03885	COG4771	TonB-dependent receptor
H9L17_RS03890	COG0052	Belongs to the universal ribosomal protein uS2 family
H9L17_RS03895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9L17_RS03900	COG0038	chloride channel
H9L17_RS03910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9L17_RS03920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9L17_RS03935	COG0495	leucyl-tRNA aminoacylation
H9L17_RS04010	COG3118	belongs to the thioredoxin family
H9L17_RS04025	COG0840	transmembrane signaling receptor activity
H9L17_RS04025	COG0840	transmembrane signaling receptor activity
H9L17_RS04035	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9L17_RS04065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9L17_RS04080	COG2197	response regulator
H9L17_RS04085	COG4585	Histidine kinase
H9L17_RS04095	COG0850	regulation of cytokinetic process
H9L17_RS04100	COG2894	cell division
H9L17_RS04105	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9L17_RS04125	COG0531	amino acid
H9L17_RS04130	COG2814	Major facilitator Superfamily
H9L17_RS04150	COG2815	serine threonine protein kinase
H9L17_RS04150	COG0515	serine threonine protein kinase
H9L17_RS04160	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L17_RS04160	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L17_RS04165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L17_RS04165	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H9L17_RS04180	COG1725	Transcriptional regulator
H9L17_RS04185	COG1131	(ABC) transporter
H9L17_RS04210	COG0330	HflC and HflK could
H9L17_RS04215	COG0330	HflC and HflK could
H9L17_RS04220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9L17_RS04225	COG1923	regulation of RNA biosynthetic process
H9L17_RS04230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9L17_RS04235	COG0531	amino acid
H9L17_RS04240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9L17_RS04245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_RS04250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9L17_RS04255	COG1534	Rna-binding protein
H9L17_RS04265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L17_RS04275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9L17_RS04295	COG0481	GTPase activity
H9L17_RS04300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L17_RS04315	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_RS04315	COG1024	Enoyl-CoA hydratase
H9L17_RS04330	COG1506	peptidase
H9L17_RS04330	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_RS04340	COG1131	(ABC) transporter
H9L17_RS04345	COG1725	Transcriptional regulator
H9L17_RS04360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9L17_RS04365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9L17_RS04375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9L17_RS04395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9L17_RS04405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L17_RS04410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9L17_RS04415	COG1399	metal-binding, possibly nucleic acid-binding protein
H9L17_RS04440	COG0714	Associated with various cellular activities
H9L17_RS04455	COG0537	adenosine 5'-monophosphoramidase activity
H9L17_RS04470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9L17_RS04515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L17_RS04530	COG2723	6-phospho-beta-galactosidase activity
H9L17_RS04565	COG3642	lipopolysaccharide core region biosynthetic process
H9L17_RS04570	COG0859	PFAM glycosyl transferase family 9
H9L17_RS04590	COG0631	protein serine/threonine phosphatase activity
H9L17_RS04595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9L17_RS04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L17_RS04645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9L17_RS04655	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9L17_RS04690	COG0473	3-isopropylmalate dehydrogenase activity
H9L17_RS04695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L17_RS04705	COG4783	chaperone-mediated protein folding
H9L17_RS04720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9L17_RS04735	COG4452	Inner membrane protein CreD
H9L17_RS04740	COG2205	protein histidine kinase activity
H9L17_RS04745	COG0745	RESPONSE REGULATOR receiver
H9L17_RS04750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9L17_RS04755	COG2354	Protein conserved in bacteria
H9L17_RS04765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9L17_RS04775	COG1515	deoxyribonuclease V activity
H9L17_RS05030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H9L17_RS05040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H9L17_RS05045	COG1137	ATPase activity
H9L17_RS05080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9L17_RS05090	COG2239	Acts as a magnesium transporter
H9L17_RS05100	COG0393	Putative heavy-metal-binding
H9L17_RS05105	COG0540	Belongs to the ATCase OTCase family
H9L17_RS05110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9L17_RS05115	COG1678	Uncharacterized ACR, COG1678
H9L17_RS05130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9L17_RS05150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9L17_RS05155	COG0259	pyridoxamine-phosphate oxidase activity
H9L17_RS05175	COG0515	serine threonine protein kinase
H9L17_RS05200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9L17_RS05215	COG3038	cytochrome b561
H9L17_RS05230	COG1760	l-serine dehydratase
H9L17_RS05235	COG3706	GGDEF domain
H9L17_RS05240	COG5002	protein histidine kinase activity
H9L17_RS05240	COG5001	Diguanylate cyclase
H9L17_RS05245	COG0527	aspartate kinase activity
H9L17_RS05245	COG0460	homoserine dehydrogenase
H9L17_RS05250	COG0626	cystathionine gamma-synthase activity
H9L17_RS05255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L17_RS05260	COG0739	heme binding
H9L17_RS05285	COG0463	Glycosyl transferase, family 2
H9L17_RS05295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9L17_RS05340	COG0457	Tetratricopeptide repeat
H9L17_RS05350	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H9L17_RS05355	COG1309	transcriptional regulator
H9L17_RS05360	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS05420	COG0210	DNA helicase
H9L17_RS05425	COG0501	Belongs to the peptidase M48B family
H9L17_RS05430	COG1704	LemA family
H9L17_RS05465	COG0330	HflC and HflK could
H9L17_RS05510	COG2119	membrane
H9L17_RS05520	COG2211	Major facilitator Superfamily
H9L17_RS05525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_RS05535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9L17_RS05540	COG0602	queuosine metabolic process
H9L17_RS05550	COG2885	chlorophyll binding
H9L17_RS05565	COG0848	biopolymer transport protein
H9L17_RS05575	COG0824	Thioesterase
H9L17_RS05580	COG2255	four-way junction helicase activity
H9L17_RS05585	COG5001	Diguanylate cyclase
H9L17_RS05585	COG3447	MASE1 domain protein
H9L17_RS05585	COG5002	protein histidine kinase activity
H9L17_RS05595	COG0632	four-way junction helicase activity
H9L17_RS05605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9L17_RS05610	COG0217	transcriptional regulatory protein
H9L17_RS05620	COG4191	Histidine kinase
H9L17_RS05625	COG3300	MHYT domain
H9L17_RS05625	COG5001	Diguanylate cyclase
H9L17_RS05630	COG2267	carboxylic ester hydrolase activity
H9L17_RS05655	COG0488	(ABC) transporter
H9L17_RS05660	COG4206	TonB-dependent receptor
H9L17_RS05665	COG4651	solute:proton antiporter activity
H9L17_RS05665	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L17_RS05670	COG5002	protein histidine kinase activity
H9L17_RS05670	COG5001	Diguanylate cyclase
H9L17_RS05675	COG0542	response to heat
H9L17_RS05685	COG2885	chlorophyll binding
H9L17_RS05720	COG3011	Protein conserved in bacteria
H9L17_RS05735	COG0564	pseudouridine synthase activity
H9L17_RS05740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L17_RS05760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9L17_RS05775	COG1917	Cupin 2, conserved barrel domain protein
H9L17_RS05775	COG2207	Transcriptional regulator
H9L17_RS05800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9L17_RS05805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9L17_RS05815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9L17_RS05820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L17_RS05825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9L17_RS05835	COG0356	it plays a direct role in the translocation of protons across the membrane
H9L17_RS05850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L17_RS05855	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L17_RS05865	COG1666	GTP binding
H9L17_RS05880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9L17_RS05885	COG1187	pseudouridine synthase activity
H9L17_RS05920	COG4941	Belongs to the sigma-70 factor family
H9L17_RS05930	COG2764	glyoxalase bleomycin resistance protein dioxygenase
H9L17_RS05935	COG3795	YCII-related domain
H9L17_RS05940	COG3795	YCII-related domain
H9L17_RS05945	COG1793	dna ligase
H9L17_RS05955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_RS05965	COG2814	Major facilitator Superfamily
H9L17_RS05970	COG2972	Histidine kinase
H9L17_RS06000	COG2818	Glycosylase
H9L17_RS06015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_RS06030	COG3588	fructose-bisphosphate aldolase
H9L17_RS06035	COG1560	Kdo2-lipid A biosynthetic process
H9L17_RS06040	COG0469	pyruvate kinase activity
H9L17_RS06045	COG0126	phosphoglycerate kinase activity
H9L17_RS06075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9L17_RS06095	COG3682	Transcriptional regulator
H9L17_RS06115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9L17_RS06170	COG0714	Associated with various cellular activities
H9L17_RS06215	COG0254	rRNA binding
H9L17_RS06260	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L17_RS06265	COG0640	Transcriptional regulator
H9L17_RS06275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9L17_RS06305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L17_RS06315	COG0194	GDP metabolic process
H9L17_RS06320	COG1561	YicC-like family, N-terminal region
H9L17_RS06325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9L17_RS06335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9L17_RS06350	COG0006	proline dipeptidase activity
H9L17_RS06360	COG0006	proline dipeptidase activity
H9L17_RS06365	COG3079	Belongs to the UPF0149 family
H9L17_RS06390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9L17_RS06405	COG0129	dihydroxy-acid dehydratase activity
H9L17_RS06410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9L17_RS06435	COG0473	3-isopropylmalate dehydrogenase activity
H9L17_RS06445	COG0066	3-isopropylmalate dehydratase activity
H9L17_RS06450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9L17_RS06460	COG3300	MHYT domain
H9L17_RS06460	COG5001	Diguanylate cyclase
H9L17_RS06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_RS06475	COG1309	transcriptional regulator
H9L17_RS06480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L17_RS06485	COG1538	Outer membrane efflux protein
H9L17_RS06490	COG1519	Transferase
H9L17_RS06495	COG1560	Kdo2-lipid A biosynthetic process
H9L17_RS06505	COG0297	glycogen (starch) synthase activity
H9L17_RS06515	COG1741	Belongs to the pirin family
H9L17_RS06520	COG2353	YceI-like domain
H9L17_RS06525	COG0778	Nitroreductase
H9L17_RS06535	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H9L17_RS06540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L17_RS06570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9L17_RS06575	COG1324	tolerance protein
H9L17_RS06580	COG4232	protein-disulfide reductase activity
H9L17_RS06585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_RS06590	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9L17_RS06595	COG0511	ligase activity, forming carbon-carbon bonds
H9L17_RS06600	COG0439	Biotin carboxylase
H9L17_RS06610	COG2264	protein methyltransferase activity
H9L17_RS06620	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9L17_RS06625	COG0138	bifunctional purine biosynthesis protein purh
H9L17_RS06630	COG0454	-acetyltransferase
H9L17_RS06630	COG0456	acetyltransferase
H9L17_RS06635	COG0151	Belongs to the GarS family
H9L17_RS06645	COG4181	ATPase activity
H9L17_RS06660	COG3384	dioxygenase
H9L17_RS06730	COG2906	2 iron, 2 sulfur cluster binding
H9L17_RS06735	COG0720	synthase
H9L17_RS06750	COG1183	phosphatidylcholine synthase activity
H9L17_RS06765	COG0442	prolyl-tRNA aminoacylation
H9L17_RS06780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L17_RS06785	COG1127	ABC transporter
H9L17_RS06815	COG2086	electron transfer activity
H9L17_RS06830	COG1215	transferase activity, transferring glycosyl groups
H9L17_RS06850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L17_RS06905	COG1459	type II secretion system
H9L17_RS06910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L17_RS06960	COG1450	Type ii and iii secretion system protein
H9L17_RS06970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9L17_RS06970	COG3620	sequence-specific DNA binding
H9L17_RS06970	COG0617	tRNA 3'-terminal CCA addition
H9L17_RS06980	COG2885	chlorophyll binding
H9L17_RS06990	COG0625	glutathione transferase activity
H9L17_RS07010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9L17_RS07015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9L17_RS07020	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H9L17_RS07035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9L17_RS07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L17_RS07060	COG0134	indole-3-glycerol-phosphate synthase activity
H9L17_RS07070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9L17_RS07080	COG0642	Histidine kinase
H9L17_RS07085	COG0745	RESPONSE REGULATOR receiver
H9L17_RS07135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9L17_RS07140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9L17_RS07150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9L17_RS07165	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9L17_RS07190	COG0673	inositol 2-dehydrogenase activity
H9L17_RS07200	COG1501	Belongs to the glycosyl hydrolase 31 family
H9L17_RS07205	COG2222	sugar isomerase
H9L17_RS07210	COG1940	carbohydrate kinase activity
H9L17_RS07220	COG1349	DNA-binding transcription factor activity
H9L17_RS07225	COG3104	oligopeptide transport
H9L17_RS07230	COG3483	tryptophan 2,3-dioxygenase activity
H9L17_RS07270	COG1846	Transcriptional regulator
H9L17_RS07280	COG0180	Tryptophanyl-tRNA synthetase
H9L17_RS07300	COG2323	membrane
H9L17_RS07310	COG1132	(ABC) transporter
H9L17_RS07320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_RS07325	COG0210	DNA helicase
H9L17_RS07350	COG1609	Transcriptional regulator
H9L17_RS07355	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L17_RS07365	COG0625	glutathione transferase activity
H9L17_RS07370	COG0662	Cupin 2, conserved barrel domain protein
H9L17_RS07375	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_RS07375	COG1506	peptidase
H9L17_RS07410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9L17_RS07445	COG0357	Ribosomal RNA small subunit methyltransferase G
H9L17_RS07450	COG1192	Involved in chromosome partitioning
H9L17_RS07460	COG0463	Glycosyl transferase, family 2
H9L17_RS07485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9L17_RS07495	COG1968	undecaprenyl-diphosphatase activity
H9L17_RS07500	COG0174	glutamine synthetase
H9L17_RS07510	COG0347	Belongs to the P(II) protein family
H9L17_RS07515	COG0004	ammonium transporteR
H9L17_RS07525	COG3023	N-Acetylmuramoyl-L-alanine amidase
H9L17_RS07530	COG4206	TonB-dependent receptor
H9L17_RS07535	COG4774	siderophore transport
H9L17_RS07585	COG3291	Pkd domain containing protein
H9L17_RS07595	COG0006	proline dipeptidase activity
H9L17_RS07610	COG3938	Belongs to the proline racemase family
H9L17_RS07615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L17_RS07660	COG1056	cytidyltransferase-related domain
H9L17_RS07660	COG1051	belongs to the nudix hydrolase family
H9L17_RS07675	COG3852	Histidine kinase
H9L17_RS07680	COG2204	response regulator
H9L17_RS07685	COG2032	superoxide dismutase activity
H9L17_RS07710	COG0515	serine threonine protein kinase
H9L17_RS07740	COG0183	Belongs to the thiolase family
H9L17_RS07775	COG1271	oxidase subunit
H9L17_RS07785	COG1294	oxidase, subunit
H9L17_RS07790	COG3100	YcgL domain-containing protein
H9L17_RS07800	COG0475	glutathione-regulated potassium exporter activity
H9L17_RS07800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L17_RS07815	COG0493	'glutamate synthase
H9L17_RS07820	COG0067	glutamate synthase
H9L17_RS07820	COG0069	glutamate synthase activity
H9L17_RS07820	COG0070	glutamate synthase
H9L17_RS07845	COG2922	Belongs to the Smg family
H9L17_RS07850	COG0758	DNA mediated transformation
H9L17_RS07860	COG0242	peptide deformylase activity
H9L17_RS07870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9L17_RS07870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L17_RS07875	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9L17_RS07880	COG0438	transferase activity, transferring glycosyl groups
H9L17_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9L17_RS07900	COG0210	DNA helicase
H9L17_RS07915	COG5001	Diguanylate cyclase
H9L17_RS07915	COG3300	MHYT domain
H9L17_RS07920	COG2937	Belongs to the GPAT DAPAT family
H9L17_RS07925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L17_RS07935	COG0037	tRNA processing
H9L17_RS07940	COG2974	May be involved in recombination
H9L17_RS07955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9L17_RS07970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L17_RS07990	COG0519	Catalyzes the synthesis of GMP from XMP
H9L17_RS07990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L17_RS08000	COG0625	glutathione transferase activity
H9L17_RS08010	COG0729	surface antigen
H9L17_RS08030	COG0445	tRNA wobble uridine modification
H9L17_RS08035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L17_RS08040	COG5002	protein histidine kinase activity
H9L17_RS08050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9L17_RS08055	COG3850	Histidine kinase
H9L17_RS08055	COG2205	protein histidine kinase activity
H9L17_RS08055	COG4999	Histidine kinase
H9L17_RS08055	COG3437	response regulator, receiver
H9L17_RS08065	COG2267	carboxylic ester hydrolase activity
H9L17_RS08075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9L17_RS08080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L17_RS08090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L17_RS08095	COG4771	TonB-dependent receptor
H9L17_RS08100	COG0457	Tetratricopeptide repeat
H9L17_RS08115	COG0156	8-amino-7-oxononanoate synthase activity
H9L17_RS08120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9L17_RS08125	COG1040	competence protein
H9L17_RS08175	COG2945	thiolester hydrolase activity
H9L17_RS08180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H9L17_RS08185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L17_RS08185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L17_RS08190	COG1652	LysM domain
H9L17_RS08210	COG1187	pseudouridine synthase activity
H9L17_RS08225	COG1643	Atp-dependent helicase
H9L17_RS08230	COG0084	hydrolase, TatD family'
H9L17_RS08245	COG0842	Transport permease protein
H9L17_RS08250	COG1131	(ABC) transporter
H9L17_RS08300	COG4964	Belongs to the GSP D family
H9L17_RS08360	COG2267	carboxylic ester hydrolase activity
H9L17_RS08365	COG4555	ABC transporter
H9L17_RS08385	COG0706	membrane insertase activity
H9L17_RS08410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9L17_RS08415	COG0187	DNA topoisomerase II activity
H9L17_RS08460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_RS08475	COG1741	Belongs to the pirin family
H9L17_RS08480	COG3273	potassium ion transport
H9L17_RS08480	COG0471	metal ion transport
H9L17_RS08485	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9L17_RS08495	COG5487	UPF0391 membrane protein
H9L17_RS08500	COG3186	Phenylalanine-4-hydroxylase
H9L17_RS08510	COG1595	DNA-templated transcription, initiation
H9L17_RS08525	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L17_RS08530	COG3647	Membrane
H9L17_RS08545	COG0861	Integral membrane protein TerC family
H9L17_RS08550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L17_RS08565	COG2853	Lipoprotein
H9L17_RS08575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L17_RS08580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L17_RS08585	COG1127	ABC transporter
H9L17_RS08590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H9L17_RS08595	COG1074	ATP-dependent DNA helicase activity
H9L17_RS08615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_RS08620	COG2226	methyltransferase
H9L17_RS08625	COG0534	Mate efflux family protein
H9L17_RS08635	COG0346	lactoylglutathione lyase activity
H9L17_RS08640	COG3122	Protein conserved in bacteria
H9L17_RS08645	COG1451	nucleotide metabolic process
H9L17_RS08660	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS08670	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H9L17_RS08670	COG3408	Glycogen debranching enzyme
H9L17_RS08685	COG0302	gtp cyclohydrolase
H9L17_RS08720	COG3550	peptidyl-serine autophosphorylation
H9L17_RS08730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9L17_RS08740	COG2188	Transcriptional regulator
H9L17_RS08745	COG1609	Transcriptional regulator
H9L17_RS08750	COG0738	Major facilitator superfamily
H9L17_RS08755	COG0837	glucose binding
H9L17_RS08765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
H9L17_RS08780	COG2062	phosphohistidine phosphatase, SixA
H9L17_RS08785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L17_RS08795	COG2050	protein possibly involved in aromatic compounds catabolism
H9L17_RS08810	COG1881	PFAM PEBP family protein
H9L17_RS08845	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9L17_RS08890	COG1505	serine-type exopeptidase activity
H9L17_RS08915	COG0612	Peptidase, M16
H9L17_RS08925	COG2932	Transcriptional regulator
H9L17_RS08935	COG2378	regulation of single-species biofilm formation
H9L17_RS08960	COG0181	hydroxymethylbilane synthase activity
H9L17_RS08980	COG1368	sulfuric ester hydrolase activity
H9L17_RS08985	COG0745	RESPONSE REGULATOR receiver
H9L17_RS08990	COG2205	protein histidine kinase activity
H9L17_RS09000	COG3537	Alpha-1,2-mannosidase
H9L17_RS09005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L17_RS09010	COG1490	D-aminoacyl-tRNA deacylase activity
H9L17_RS09025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9L17_RS09035	COG0515	serine threonine protein kinase
H9L17_RS09040	COG3590	peptidase
H9L17_RS09045	COG0477	Major facilitator Superfamily
H9L17_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS09090	COG0616	signal peptide processing
H9L17_RS09095	COG0534	Mate efflux family protein
H9L17_RS09115	COG4585	Histidine kinase
H9L17_RS09130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9L17_RS09140	COG3250	beta-galactosidase activity
H9L17_RS09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_RS09160	COG1609	Transcriptional regulator
H9L17_RS09165	COG3537	Alpha-1,2-mannosidase
H9L17_RS09180	COG1252	NADH dehydrogenase
H9L17_RS09185	COG2860	membrane
H9L17_RS09200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L17_RS09205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9L17_RS09220	COG2022	thiamine diphosphate biosynthetic process
H9L17_RS09235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9L17_RS09260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9L17_RS09265	COG3118	belongs to the thioredoxin family
H9L17_RS09275	COG2884	Cell division ATP-binding protein ftsE
H9L17_RS09280	COG2177	Part of the ABC transporter FtsEX involved in
H9L17_RS09285	COG2201	protein-glutamate methylesterase activity
H9L17_RS09295	COG0308	aminopeptidase N
H9L17_RS09300	COG0596	Alpha beta hydrolase
H9L17_RS09300	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L17_RS09325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_RS09330	COG1077	Cell shape determining protein MreB Mrl
H9L17_RS09340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H9L17_RS09345	COG0768	penicillin binding
H9L17_RS09350	COG0772	Belongs to the SEDS family
H9L17_RS09355	COG2951	lytic endotransglycosylase activity
H9L17_RS09360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9L17_RS09370	COG1686	Belongs to the peptidase S11 family
H9L17_RS09375	COG2921	Belongs to the UPF0250 family
H9L17_RS09380	COG0321	lipoyl(octanoyl) transferase activity
H9L17_RS09390	COG0697	spore germination
H9L17_RS09405	COG0577	efflux transmembrane transporter activity
H9L17_RS09410	COG0577	efflux transmembrane transporter activity
H9L17_RS09415	COG1136	(ABC) transporter
H9L17_RS09420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_RS09425	COG1131	(ABC) transporter
H9L17_RS09435	COG4585	Histidine kinase
H9L17_RS09440	COG2197	response regulator
H9L17_RS09455	COG0753	catalase activity
H9L17_RS09470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L17_RS09480	COG0628	permease
H9L17_RS09500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L17_RS09575	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9L17_RS09630	COG2234	aminopeptidase activity
H9L17_RS09650	COG2824	Alkylphosphonate utilization operon protein PhnA
H9L17_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS09680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L17_RS09705	COG3228	Belongs to the MtfA family
H9L17_RS09720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9L17_RS09735	COG0010	Belongs to the arginase family
H9L17_RS09745	COG0408	coproporphyrinogen oxidase activity
H9L17_RS09750	COG0697	spore germination
H9L17_RS09780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L17_RS09785	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9L17_RS09790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9L17_RS09800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9L17_RS09810	COG0612	Peptidase, M16
H9L17_RS09820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L17_RS09825	COG1573	uracil-dna glycosylase
H9L17_RS09835	COG0596	Alpha beta hydrolase
H9L17_RS09855	COG2852	Protein conserved in bacteria
H9L17_RS09860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L17_RS09880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_RS09915	COG0564	pseudouridine synthase activity
H9L17_RS09940	COG1216	Glycosyl transferase, family 2
H9L17_RS09980	COG0583	DNA-binding transcription factor activity
H9L17_RS09985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9L17_RS09990	COG2224	Isocitrate lyase
H9L17_RS10015	COG0606	chelatase, subunit chli
H9L17_RS10020	COG2960	long-chain fatty acid transporting porin activity
H9L17_RS10025	COG0347	Belongs to the P(II) protein family
H9L17_RS10035	COG1166	arginine decarboxylase activity
H9L17_RS10060	COG3275	phosphorelay sensor kinase activity
H9L17_RS10065	COG3279	Response regulator of the LytR AlgR family
H9L17_RS10070	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L17_RS10070	COG2755	lipolytic protein G-D-S-L family
H9L17_RS10090	COG3596	GTP binding
H9L17_RS10095	COG4735	regulation of single-species biofilm formation
H9L17_RS10120	COG5001	Diguanylate cyclase
H9L17_RS10125	COG3447	MASE1 domain protein
H9L17_RS10125	COG5001	Diguanylate cyclase
H9L17_RS10125	COG5002	protein histidine kinase activity
H9L17_RS10130	COG4221	oxidoreductase activity
H9L17_RS10155	COG0018	arginyl-trna synthetase
H9L17_RS10165	COG2003	Belongs to the UPF0758 family
H9L17_RS10180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L17_RS10190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9L17_RS10205	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9L17_RS10210	COG0739	heme binding
H9L17_RS10215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L17_RS10250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9L17_RS10265	COG0577	efflux transmembrane transporter activity
H9L17_RS10270	COG0577	efflux transmembrane transporter activity
H9L17_RS10270	COG0577	efflux transmembrane transporter activity
H9L17_RS10270	COG1136	(ABC) transporter
H9L17_RS10270	COG1136	(ABC) transporter
H9L17_RS10275	COG0577	efflux transmembrane transporter activity
H9L17_RS10285	COG0577	efflux transmembrane transporter activity
H9L17_RS10290	COG1136	(ABC) transporter
H9L17_RS10290	COG0577	efflux transmembrane transporter activity
H9L17_RS10295	COG1136	(ABC) transporter
H9L17_RS10295	COG0577	efflux transmembrane transporter activity
H9L17_RS10310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9L17_RS10330	COG3781	membrane
H9L17_RS10340	COG0243	molybdopterin cofactor binding
H9L17_RS10355	COG2823	Periplasmic or secreted lipoprotein
H9L17_RS10370	COG1956	GAF domain-containing protein
H9L17_RS10380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9L17_RS10385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L17_RS10390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_RS10425	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L17_RS10445	COG4974	Belongs to the 'phage' integrase family
H9L17_RS10450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L17_RS10455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9L17_RS10455	COG0047	phosphoribosylformylglycinamidine synthase activity
H9L17_RS10460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L17_RS10465	COG1459	type II secretion system
H9L17_RS10470	COG2165	general secretion pathway protein
H9L17_RS10480	COG2165	general secretion pathway protein
H9L17_RS10485	COG4795	General secretion pathway protein
H9L17_RS10490	COG3156	type II secretion system protein K
H9L17_RS10495	COG3166	PFAM Fimbrial assembly family protein
H9L17_RS10510	COG1450	Type ii and iii secretion system protein
H9L17_RS10525	COG0284	orotidine-5'-phosphate decarboxylase activity
H9L17_RS10550	COG0488	(ABC) transporter
H9L17_RS10570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9L17_RS10600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9L17_RS10605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L17_RS10620	COG0277	FAD linked oxidase domain protein
H9L17_RS10625	COG0792	nuclease activity
H9L17_RS10670	COG2001	Belongs to the MraZ family
H9L17_RS10675	COG0275	rRNA processing
H9L17_RS10680	COG3116	cell division
H9L17_RS10695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9L17_RS10700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L17_RS10715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L17_RS10720	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9L17_RS10725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9L17_RS10750	COG0739	heme binding
H9L17_RS10755	COG0653	protein targeting
H9L17_RS10760	COG0494	nUDIX hydrolase
H9L17_RS10770	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9L17_RS10785	COG0463	Glycosyl transferase, family 2
H9L17_RS10790	COG0438	transferase activity, transferring glycosyl groups
H9L17_RS10795	COG1215	transferase activity, transferring glycosyl groups
H9L17_RS10800	COG1442	glycosyl transferase family 8
H9L17_RS10835	COG2755	lipolytic protein G-D-S-L family
H9L17_RS10835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L17_RS10870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9L17_RS10875	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H9L17_RS10885	COG1872	DUF167
H9L17_RS10910	COG0563	adenylate kinase activity
H9L17_RS10915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L17_RS10920	COG0671	phosphoesterase, PA-phosphatase related
H9L17_RS10925	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS10930	COG0346	lactoylglutathione lyase activity
H9L17_RS10935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L17_RS10940	COG4771	TonB-dependent receptor
H9L17_RS10950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L17_RS10955	COG1846	Transcriptional regulator
H9L17_RS10955	COG1940	carbohydrate kinase activity
H9L17_RS10975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9L17_RS10980	COG1773	rubredoxin
H9L17_RS11020	COG2234	aminopeptidase activity
H9L17_RS11030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9L17_RS11035	COG4942	peptidase
H9L17_RS11040	COG0793	Belongs to the peptidase S41A family
H9L17_RS11060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L17_RS11065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L17_RS11075	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9L17_RS11105	COG0109	protoheme IX farnesyltransferase activity
H9L17_RS11110	COG3145	DNA-N1-methyladenine dioxygenase activity
H9L17_RS11115	COG2169	Transcriptional regulator
H9L17_RS11115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L17_RS11120	COG0038	chloride channel
H9L17_RS11135	COG0358	DNA primase activity
H9L17_RS11140	COG1295	ribonuclease BN
H9L17_RS11160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9L17_RS11165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9L17_RS11170	COG0300	oxidoreductase activity
H9L17_RS11195	COG0617	tRNA 3'-terminal CCA addition
H9L17_RS11205	COG0730	response to heat
H9L17_RS11225	COG2863	cytochrome
H9L17_RS11240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9L17_RS11245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H9L17_RS11270	COG1307	EDD domain protein, DegV family
H9L17_RS11280	COG1228	amidohydrolase
H9L17_RS11300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9L17_RS11320	COG3038	cytochrome b561
H9L17_RS11330	COG0436	Aminotransferase
H9L17_RS11335	COG1162	GTPase activity
H9L17_RS11345	COG0280	phosphate acetyltransferase
H9L17_RS11345	COG0281	malic enzyme
H9L17_RS11355	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H9L17_RS11365	COG1970	mechanosensitive ion channel activity
H9L17_RS11390	COG3273	potassium ion transport
H9L17_RS11390	COG0471	metal ion transport
H9L17_RS11415	COG0745	RESPONSE REGULATOR receiver
H9L17_RS11420	COG0642	Histidine kinase
H9L17_RS11425	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9L17_RS11435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9L17_RS11450	COG3275	phosphorelay sensor kinase activity
H9L17_RS11455	COG3279	Response regulator of the LytR AlgR family
H9L17_RS11460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9L17_RS11465	COG0488	(ABC) transporter
H9L17_RS11490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_RS11500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L17_RS11520	COG0514	ATP-dependent DNA helicase (RecQ)
H9L17_RS11525	COG0783	Belongs to the Dps family
H9L17_RS11530	COG1643	Atp-dependent helicase
H9L17_RS11535	COG1643	Atp-dependent helicase
H9L17_RS11540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L17_RS11550	COG1216	Glycosyl transferase, family 2
H9L17_RS11550	COG0438	transferase activity, transferring glycosyl groups
H9L17_RS11555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L17_RS11560	COG1199	ATP-dependent helicase activity
H9L17_RS11585	COG0189	ligase activity
H9L17_RS11605	COG0840	transmembrane signaling receptor activity
H9L17_RS11610	COG0643	Histidine kinase
H9L17_RS11610	COG2198	Histidine kinase
H9L17_RS11610	COG0784	Response regulator, receiver
H9L17_RS11615	COG2201	protein-glutamate methylesterase activity
H9L17_RS11630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9L17_RS11640	COG0494	nUDIX hydrolase
H9L17_RS11645	COG1218	3'(2'),5'-bisphosphate nucleotidase
H9L17_RS11650	COG3956	TIGRFAM MazG family protein
H9L17_RS11670	COG0642	Histidine kinase
H9L17_RS11675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L17_RS11680	COG1136	(ABC) transporter
H9L17_RS11680	COG0577	efflux transmembrane transporter activity
H9L17_RS11685	COG0577	efflux transmembrane transporter activity
H9L17_RS11685	COG1136	(ABC) transporter
H9L17_RS11690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9L17_RS11695	COG0861	Integral membrane protein TerC family
H9L17_RS11700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9L17_RS11715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9L17_RS11720	COG2967	ApaG domain
H9L17_RS11730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L17_RS11735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9L17_RS11740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L17_RS11745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H9L17_RS11750	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L17_RS11755	COG2096	Adenosyltransferase
H9L17_RS11765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_RS11770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_RS11790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L17_RS11810	COG0583	DNA-binding transcription factor activity
H9L17_RS11850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L17_RS11850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L17_RS11890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H9L17_RS11900	COG2151	metal-sulfur cluster biosynthetic enzyme
H9L17_RS11905	COG3227	Zinc metalloprotease (Elastase)
H9L17_RS11915	COG0457	Tetratricopeptide repeat
H9L17_RS11930	COG1295	ribonuclease BN
H9L17_RS11935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L17_RS11940	COG1254	Belongs to the acylphosphatase family
H9L17_RS11955	COG0456	acetyltransferase
H9L17_RS11960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9L17_RS11965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L17_RS11980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9L17_RS11990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9L17_RS12000	COG0193	aminoacyl-tRNA hydrolase activity
H9L17_RS12005	COG0012	GTP binding
H9L17_RS12025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L17_RS12035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L17_RS12040	COG0250	Participates in transcription elongation, termination and antitermination
H9L17_RS12045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9L17_RS12055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9L17_RS12060	COG0222	ribosome binding
H9L17_RS12070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9L17_RS12075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9L17_RS12080	COG0049	tRNA binding
H9L17_RS12085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9L17_RS12090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L17_RS12095	COG0051	transcription antitermination factor activity, RNA binding
H9L17_RS12100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9L17_RS12105	COG0088	Forms part of the polypeptide exit tunnel
H9L17_RS12110	COG0089	rRNA binding
H9L17_RS12115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9L17_RS12125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9L17_RS12130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9L17_RS12135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9L17_RS12145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9L17_RS12155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9L17_RS12160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9L17_RS12175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9L17_RS12180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9L17_RS12185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9L17_RS12190	COG1841	ribosomal large subunit assembly
H9L17_RS12195	COG0200	Binds to the 23S rRNA
H9L17_RS12200	COG0201	protein transport
H9L17_RS12205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9L17_RS12210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9L17_RS12215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9L17_RS12225	COG0203	ribosomal protein L17
H9L17_RS12235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
H9L17_RS12245	COG0154	amidase activity
H9L17_RS12255	COG1217	gtp-binding protein TYPA
H9L17_RS12260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L17_RS12275	COG0039	L-malate dehydrogenase activity
H9L17_RS12280	COG3706	GGDEF domain
H9L17_RS12295	COG0625	glutathione transferase activity
H9L17_RS12305	COG1902	pentaerythritol trinitrate reductase activity
H9L17_RS12305	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L17_RS12320	COG1187	pseudouridine synthase activity
H9L17_RS12325	COG0156	8-amino-7-oxononanoate synthase activity
H9L17_RS12335	COG1063	alcohol dehydrogenase
H9L17_RS12350	COG0406	alpha-ribazole phosphatase activity
H9L17_RS12355	COG4989	oxidoreductase activity
H9L17_RS12360	COG0285	dihydrofolate synthase activity
H9L17_RS12375	COG2833	Protein of unknown function (DUF455)
H9L17_RS12390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_RS12395	COG0515	serine threonine protein kinase
H9L17_RS12425	COG0735	belongs to the Fur family
H9L17_RS12450	COG1228	amidohydrolase
H9L17_RS12455	COG0010	Belongs to the arginase family
H9L17_RS12460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L17_RS12470	COG1309	transcriptional regulator
H9L17_RS12490	COG0488	(ABC) transporter
H9L17_RS12505	COG2837	iron assimilation
H9L17_RS12525	COG1073	alpha beta
H9L17_RS12530	COG0823	Involved in the tonB-independent uptake of proteins
H9L17_RS12530	COG1506	peptidase
H9L17_RS12545	COG0513	Belongs to the DEAD box helicase family
H9L17_RS12560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9L17_RS12585	COG3409	Peptidoglycan-binding domain 1 protein
H9L17_RS12585	COG3267	Type II secretory pathway component ExeA
H9L17_RS12600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9L17_RS12615	COG0384	phenazine biosynthesis protein PhzF
H9L17_RS12620	COG0527	aspartate kinase activity
H9L17_RS12630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9L17_RS12640	COG0142	geranyltranstransferase activity
H9L17_RS12645	COG0629	single-stranded DNA binding
H9L17_RS12655	COG0791	NLP P60 protein
H9L17_RS12660	COG0791	NLP P60 protein
H9L17_RS12670	COG2311	Membrane
H9L17_RS12675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L17_RS12695	COG1446	asparaginase
H9L17_RS12700	COG3142	Participates in the control of copper homeostasis
H9L17_RS12710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9L17_RS12715	COG0148	phosphopyruvate hydratase activity
H9L17_RS12720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9L17_RS12730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L17_RS12760	COG1238	metal cluster binding
H9L17_RS12780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9L17_RS12795	COG0628	permease
H9L17_RS12805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9L17_RS12810	COG3178	'Phosphotransferase
H9L17_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS12870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9L17_RS12870	COG1648	precorrin-2 dehydrogenase activity
H9L17_RS12875	COG0583	DNA-binding transcription factor activity
H9L17_RS12885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L17_RS12895	COG1959	2 iron, 2 sulfur cluster binding
H9L17_RS12910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H9L17_RS12920	COG4208	sulfate ABC transporter
H9L17_RS12925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9L17_RS12965	COG0424	maF-like protein
H9L17_RS12980	COG0312	modulator of DNA gyrase
H9L17_RS12990	COG0312	modulator of DNA gyrase
H9L17_RS13005	COG0142	geranyltranstransferase activity
H9L17_RS13010	COG1722	exodeoxyribonuclease VII activity
H9L17_RS13015	COG0037	tRNA processing
H9L17_RS13020	COG0825	malonyl-CoA metabolic process
H9L17_RS13035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_RS13040	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L17_RS13045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L17_RS13060	COG0750	zinc metalloprotease
H9L17_RS13065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9L17_RS13070	COG0575	Belongs to the CDS family
H9L17_RS13075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9L17_RS13090	COG3706	GGDEF domain
H9L17_RS13100	COG4970	Tfp pilus assembly protein FimT
H9L17_RS13115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9L17_RS13120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9L17_RS13135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9L17_RS13205	COG1073	alpha beta
H9L17_RS13235	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9L17_RS13255	COG1946	Acyl-CoA thioesterase
H9L17_RS13275	COG0116	Belongs to the methyltransferase superfamily
H9L17_RS13275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L17_RS13280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9L17_RS13290	COG1177	transmembrane transport
H9L17_RS13295	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9L17_RS13300	COG3842	ATPase activity
H9L17_RS13305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9L17_RS13320	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS13335	COG3590	peptidase
H9L17_RS13340	COG3590	peptidase
H9L17_RS13350	COG0612	Peptidase, M16
H9L17_RS13370	COG3275	phosphorelay sensor kinase activity
H9L17_RS13380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H9L17_RS13400	COG0513	Belongs to the DEAD box helicase family
H9L17_RS13405	COG2194	sulfuric ester hydrolase activity
H9L17_RS13410	COG0840	transmembrane signaling receptor activity
H9L17_RS13425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9L17_RS13430	COG0719	Fe-S assembly protein
H9L17_RS13435	COG0396	ATPase activity
H9L17_RS13440	COG0719	Fe-S assembly protein
H9L17_RS13445	COG1959	2 iron, 2 sulfur cluster binding
H9L17_RS13515	COG0457	Tetratricopeptide repeat
H9L17_RS13520	COG4771	TonB-dependent receptor
H9L17_RS13530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9L17_RS13550	COG1981	membrane
H9L17_RS13555	COG1785	Belongs to the alkaline phosphatase family
H9L17_RS13560	COG1301	dicarboxylic acid transport
H9L17_RS13580	COG3387	PFAM Glycoside hydrolase 15-related
H9L17_RS13585	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H9L17_RS13630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L17_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS13725	COG0557	exoribonuclease II activity
H9L17_RS13735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L17_RS13750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9L17_RS13770	COG0704	Plays a role in the regulation of phosphate uptake
H9L17_RS13785	COG0573	inorganic phosphate transmembrane transporter activity
H9L17_RS13805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L17_RS13815	COG1024	Enoyl-CoA hydratase
H9L17_RS13835	COG1393	Belongs to the ArsC family
H9L17_RS13855	COG0824	Thioesterase
H9L17_RS13860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9L17_RS13865	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9L17_RS13870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9L17_RS13875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9L17_RS13880	COG0268	Binds directly to 16S ribosomal RNA
H9L17_RS13885	COG0728	peptidoglycan biosynthetic process
H9L17_RS13890	COG0196	riboflavin kinase activity
H9L17_RS13905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9L17_RS13925	COG2814	Major facilitator Superfamily
H9L17_RS13930	COG1566	PFAM secretion protein HlyD family protein
H9L17_RS13945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9L17_RS13965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9L17_RS13970	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9L17_RS13970	COG0315	cyclic pyranopterin monophosphate synthase activity
H9L17_RS13975	COG0303	'Molybdopterin
H9L17_RS13985	COG0314	molybdopterin synthase activity
H9L17_RS13990	COG0746	molybdenum cofactor guanylyltransferase activity
H9L17_RS14005	COG2223	nitrite transmembrane transporter activity
H9L17_RS14010	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H9L17_RS14015	COG1140	nitrate reductase beta subunit
H9L17_RS14020	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H9L17_RS14025	COG2181	nitrate reductase activity
H9L17_RS14030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L17_RS14040	COG4771	TonB-dependent receptor
H9L17_RS14050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L17_RS14075	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H9L17_RS14080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9L17_RS14085	COG4772	TonB-dependent receptor
H9L17_RS14100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9L17_RS14115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9L17_RS14125	COG5002	protein histidine kinase activity
H9L17_RS14125	COG5001	Diguanylate cyclase
H9L17_RS14125	COG3447	MASE1 domain protein
H9L17_RS14130	COG0228	four-way junction DNA binding
H9L17_RS14135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9L17_RS14140	COG0336	Belongs to the RNA methyltransferase TrmD family
H9L17_RS14165	COG1522	sequence-specific DNA binding
H9L17_RS14170	COG0626	cystathionine gamma-synthase activity
H9L17_RS14185	COG0753	catalase activity
H9L17_RS14190	COG2258	MOSC domain
H9L17_RS14205	COG1546	Belongs to the CinA family
H9L17_RS14215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9L17_RS14220	COG2137	regulation of response to DNA damage stimulus
H9L17_RS14235	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H9L17_RS14315	COG4791	protein targeting
H9L17_RS14325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9L17_RS14330	COG4786	Flagellar basal body rod
H9L17_RS14335	COG4786	Flagellar basal body rod
H9L17_RS14350	COG1706	bacterial-type flagellum-dependent cell motility
H9L17_RS14365	COG1677	Flagellar hook-basal body complex protein FliE
H9L17_RS14385	COG1157	protein secretion by the type III secretion system
H9L17_RS14400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9L17_RS14435	COG1191	sigma factor activity
H9L17_RS14465	COG0366	Alpha amylase catalytic
H9L17_RS14470	COG1082	Xylose isomerase domain protein TIM barrel
H9L17_RS14485	COG1695	Transcriptional regulator
H9L17_RS14505	COG3620	sequence-specific DNA binding
H9L17_RS14510	COG1073	alpha beta
H9L17_RS14515	COG0800	Aldolase
H9L17_RS14535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9L17_RS14555	COG0659	secondary active sulfate transmembrane transporter activity
H9L17_RS14570	COG2944	sequence-specific DNA binding
H9L17_RS14580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9L17_RS14585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L17_RS14595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L17_RS14605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H9L17_RS14615	COG2166	iron-sulfur cluster assembly
H9L17_RS14630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9L17_RS14635	COG0137	argininosuccinate synthase activity
H9L17_RS14640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L17_RS14645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9L17_RS14650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9L17_RS14655	COG0165	Argininosuccinate lyase
H9L17_RS14665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9L17_RS14680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9L17_RS14690	COG0124	histidyl-tRNA synthetase
H9L17_RS14695	COG2986	histidine ammonia-lyase
H9L17_RS14705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9L17_RS14710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9L17_RS14715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L17_RS14725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9L17_RS14730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9L17_RS14740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9L17_RS14740	COG0140	phosphoribosyl-ATP diphosphatase activity
H9L17_RS14745	COG3706	GGDEF domain
H9L17_RS14745	COG4251	negative regulation of phosphorylation
H9L17_RS14745	COG5001	Diguanylate cyclase
H9L17_RS14745	COG2203	Gaf domain
H9L17_RS14755	COG0697	spore germination
H9L17_RS14760	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
H9L17_RS14765	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9L17_RS14770	COG0235	Class ii aldolase
H9L17_RS14775	COG0235	Class ii aldolase
H9L17_RS14780	COG0531	amino acid
H9L17_RS14785	COG0531	amino acid
H9L17_RS14795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L17_RS14800	COG0277	FAD linked oxidase domain protein
H9L17_RS14820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9L17_RS14860	COG1024	Enoyl-CoA hydratase
H9L17_RS14860	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L17_RS14870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9L17_RS14870	COG1918	ferrous iron import across plasma membrane
H9L17_RS14905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L17_RS14910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L17_RS14915	COG2954	triphosphatase activity
H9L17_RS14920	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L17_RS14925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9L17_RS14930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9L17_RS14935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L17_RS14940	COG1278	Cold shock
H9L17_RS14955	COG0183	Belongs to the thiolase family
H9L17_RS14960	COG1404	Belongs to the peptidase S8 family
H9L17_RS14965	COG2915	High frequency lysogenization protein hflD homolog
H9L17_RS14970	COG0482	sulfurtransferase activity
H9L17_RS14985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9L17_RS14990	COG0542	response to heat
H9L17_RS15010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L17_RS15040	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9L17_RS15050	COG1024	Enoyl-CoA hydratase
H9L17_RS15055	COG1024	Enoyl-CoA hydratase
H9L17_RS15060	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS15085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9L17_RS15115	COG2183	response to ionizing radiation
H9L17_RS15125	COG0477	Major facilitator Superfamily
H9L17_RS15135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9L17_RS15145	COG0025	NhaP-type Na H and K H
H9L17_RS15150	COG2610	gluconate transmembrane transporter activity
H9L17_RS15155	COG4771	TonB-dependent receptor
H9L17_RS15160	COG2205	protein histidine kinase activity
H9L17_RS15165	COG2197	response regulator
H9L17_RS15170	COG1530	ribonuclease E activity
H9L17_RS15180	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9L17_RS15185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9L17_RS15185	COG0316	Belongs to the HesB IscA family
H9L17_RS15195	COG1742	UPF0060 membrane protein
H9L17_RS15210	COG0017	Asparaginyl-tRNA synthetase
H9L17_RS15215	COG0316	Belongs to the HesB IscA family
H9L17_RS15220	COG0360	Binds together with S18 to 16S ribosomal RNA
H9L17_RS15225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9L17_RS15230	COG0359	binds to the 23S rRNA
H9L17_RS15235	COG0305	Participates in initiation and elongation during chromosome replication
H9L17_RS15240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9L17_RS15285	COG0745	RESPONSE REGULATOR receiver
H9L17_RS15330	COG0492	ferredoxin-NADP+ reductase activity
H9L17_RS15335	COG0686	Belongs to the AlaDH PNT family
H9L17_RS15340	COG1674	ftsk spoiiie
H9L17_RS15350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9L17_RS15355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9L17_RS15380	COG3300	MHYT domain
H9L17_RS15380	COG5001	Diguanylate cyclase
H9L17_RS15395	COG0840	transmembrane signaling receptor activity
H9L17_RS15405	COG0840	transmembrane signaling receptor activity
H9L17_RS15410	COG0835	chemotaxis
H9L17_RS15415	COG1960	acyl-CoA dehydrogenase activity
H9L17_RS15430	COG1703	isobutyryl-CoA mutase activity
H9L17_RS15430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L17_RS15430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9L17_RS15490	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L17_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
H9L17_RS15575	COG3706	GGDEF domain
H9L17_RS15585	COG1131	(ABC) transporter
H9L17_RS15605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H9L17_RS15695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9L17_RS15700	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9L17_RS15705	COG0813	purine-nucleoside phosphorylase activity
H9L17_RS15730	COG0204	Acyl-transferase
H9L17_RS15735	COG3038	cytochrome b561
H9L17_RS15750	COG0251	oxidation-reduction process
H9L17_RS15775	COG3590	peptidase
H9L17_RS15820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9L17_RS15835	COG4221	oxidoreductase activity