locus-tag	class	description
G7079_RS00020	COG0321	lipoyl(octanoyl) transferase activity
G7079_RS00025	COG2921	Belongs to the UPF0250 family
G7079_RS00030	COG2199	diguanylate cyclase activity
G7079_RS00030	COG2200	EAL domain
G7079_RS00030	COG2203	Gaf domain
G7079_RS00035	COG1686	Belongs to the peptidase S11 family
G7079_RS00040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7079_RS00045	COG2951	lytic endotransglycosylase activity
G7079_RS00050	COG0772	Belongs to the SEDS family
G7079_RS00055	COG0768	penicillin binding
G7079_RS00065	COG1792	Involved in formation and maintenance of cell shape
G7079_RS00070	COG1077	Cell shape determining protein MreB Mrl
G7079_RS00075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7079_RS00100	COG0308	aminopeptidase N
G7079_RS00115	COG2226	methyltransferase
G7079_RS00120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7079_RS00130	COG1215	transferase activity, transferring glycosyl groups
G7079_RS00155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7079_RS00175	COG1505	serine-type exopeptidase activity
G7079_RS00195	COG0243	molybdopterin cofactor binding
G7079_RS00205	COG0437	4 iron, 4 sulfur cluster binding
G7079_RS00210	COG0393	Putative heavy-metal-binding
G7079_RS00215	COG3302	dmso reductase anchor subunit
G7079_RS00225	COG0181	hydroxymethylbilane synthase activity
G7079_RS00275	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G7079_RS00285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7079_RS00290	COG1490	D-aminoacyl-tRNA deacylase activity
G7079_RS00315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_RS00320	COG0438	transferase activity, transferring glycosyl groups
G7079_RS00335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7079_RS00335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7079_RS00345	COG0242	peptide deformylase activity
G7079_RS00350	COG1652	LysM domain
G7079_RS00360	COG2922	Belongs to the Smg family
G7079_RS00365	COG1754	DNA topoisomerase type I activity
G7079_RS00365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7079_RS00370	COG1764	response to oxidative stress
G7079_RS00375	COG0009	L-threonylcarbamoyladenylate synthase
G7079_RS00390	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS00400	COG2755	lipolytic protein G-D-S-L family
G7079_RS00405	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS00415	COG1609	Transcriptional regulator
G7079_RS00435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G7079_RS00450	COG2272	Belongs to the type-B carboxylesterase lipase family
G7079_RS00465	COG0616	signal peptide processing
G7079_RS00470	COG0534	Mate efflux family protein
G7079_RS00490	COG4585	Histidine kinase
G7079_RS00510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7079_RS00525	COG1902	pentaerythritol trinitrate reductase activity
G7079_RS00550	COG2860	membrane
G7079_RS00570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7079_RS00580	COG2177	Part of the ABC transporter FtsEX involved in
G7079_RS00585	COG2884	Cell division ATP-binding protein ftsE
G7079_RS00590	COG0513	Belongs to the DEAD box helicase family
G7079_RS00595	COG3118	belongs to the thioredoxin family
G7079_RS00600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G7079_RS00620	COG3100	YcgL domain-containing protein
G7079_RS00625	COG1294	oxidase, subunit
G7079_RS00630	COG1271	oxidase subunit
G7079_RS00640	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G7079_RS00645	COG0183	Belongs to the thiolase family
G7079_RS00665	COG0515	serine threonine protein kinase
G7079_RS00685	COG2032	superoxide dismutase activity
G7079_RS00690	COG2204	response regulator
G7079_RS00695	COG3852	Histidine kinase
G7079_RS00735	COG1376	ErfK ybiS ycfS ynhG family protein
G7079_RS00745	COG3023	N-Acetylmuramoyl-L-alanine amidase
G7079_RS00750	COG0069	glutamate synthase activity
G7079_RS00750	COG0070	glutamate synthase
G7079_RS00750	COG0067	glutamate synthase
G7079_RS00755	COG0493	'glutamate synthase
G7079_RS00770	COG0667	Aldo Keto reductase
G7079_RS00775	COG0656	L-ascorbic acid biosynthetic process
G7079_RS00785	COG0667	Aldo Keto reductase
G7079_RS00805	COG0789	Transcriptional regulator
G7079_RS00820	COG0004	ammonium transporteR
G7079_RS00830	COG0174	glutamine synthetase
G7079_RS00835	COG1968	undecaprenyl-diphosphatase activity
G7079_RS00850	COG2267	carboxylic ester hydrolase activity
G7079_RS00870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_RS00885	COG4999	Histidine kinase
G7079_RS00885	COG3850	Histidine kinase
G7079_RS00885	COG3437	response regulator, receiver
G7079_RS00885	COG2205	protein histidine kinase activity
G7079_RS00925	COG0302	gtp cyclohydrolase
G7079_RS00970	COG1451	nucleotide metabolic process
G7079_RS00975	COG3122	Protein conserved in bacteria
G7079_RS00990	COG0640	Transcriptional regulator
G7079_RS01020	COG1074	ATP-dependent DNA helicase activity
G7079_RS01025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G7079_RS01030	COG1127	ABC transporter
G7079_RS01035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7079_RS01040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7079_RS01055	COG2853	Lipoprotein
G7079_RS01070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7079_RS01075	COG0861	Integral membrane protein TerC family
G7079_RS01085	COG3647	Membrane
G7079_RS01090	COG1752	Esterase of the alpha-beta hydrolase superfamily
G7079_RS01095	COG3186	Phenylalanine-4-hydroxylase
G7079_RS01100	COG4772	TonB-dependent receptor
G7079_RS01110	COG4585	Histidine kinase
G7079_RS01135	COG0784	Response regulator, receiver
G7079_RS01145	COG3273	potassium ion transport
G7079_RS01145	COG0471	metal ion transport
G7079_RS01150	COG1741	Belongs to the pirin family
G7079_RS01160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_RS01210	COG0187	DNA topoisomerase II activity
G7079_RS01215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G7079_RS01235	COG0594	ribonuclease P activity
G7079_RS01240	COG0706	membrane insertase activity
G7079_RS01260	COG4555	ABC transporter
G7079_RS01290	COG1131	(ABC) transporter
G7079_RS01295	COG0842	Transport permease protein
G7079_RS01300	COG0084	hydrolase, TatD family'
G7079_RS01305	COG1643	Atp-dependent helicase
G7079_RS01320	COG1187	pseudouridine synthase activity
G7079_RS01340	COG1652	LysM domain
G7079_RS01345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7079_RS01345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7079_RS01350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G7079_RS01355	COG2945	thiolester hydrolase activity
G7079_RS01365	COG3468	outer membrane autotransporter barrel domain protein
G7079_RS01405	COG1040	competence protein
G7079_RS01410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7079_RS01415	COG0156	8-amino-7-oxononanoate synthase activity
G7079_RS01430	COG0697	spore germination
G7079_RS01470	COG0729	surface antigen
G7079_RS01485	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_RS01485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_RS01520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G7079_RS01550	COG0037	tRNA processing
G7079_RS01560	COG2937	Belongs to the GPAT DAPAT family
G7079_RS01570	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
G7079_RS01575	COG0210	DNA helicase
G7079_RS01585	COG2815	serine threonine protein kinase
G7079_RS01585	COG0515	serine threonine protein kinase
G7079_RS01595	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7079_RS01610	COG2826	transposase and inactivated derivatives, IS30 family
G7079_RS01615	COG3590	peptidase
G7079_RS01620	COG0477	Major facilitator Superfamily
G7079_RS01645	COG1538	Outer membrane efflux protein
G7079_RS01650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_RS01665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7079_RS01670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7079_RS01685	COG0463	Glycosyl transferase, family 2
G7079_RS01690	COG1475	DNA binding
G7079_RS01695	COG1192	Involved in chromosome partitioning
G7079_RS01700	COG0357	Ribosomal RNA small subunit methyltransferase G
G7079_RS01705	COG2091	lysine biosynthetic process via aminoadipic acid
G7079_RS01725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G7079_RS01750	COG0463	Glycosyl transferase, family 2
G7079_RS01755	COG1506	peptidase
G7079_RS01755	COG0823	Involved in the tonB-independent uptake of proteins
G7079_RS01760	COG0625	glutathione transferase activity
G7079_RS01770	COG0210	DNA helicase
G7079_RS01775	COG4807	Protein conserved in bacteria
G7079_RS01795	COG1132	(ABC) transporter
G7079_RS01805	COG2323	membrane
G7079_RS01810	COG0408	coproporphyrinogen oxidase activity
G7079_RS01840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7079_RS01845	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G7079_RS01850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7079_RS01865	COG2205	protein histidine kinase activity
G7079_RS01870	COG0745	RESPONSE REGULATOR receiver
G7079_RS01875	COG1368	sulfuric ester hydrolase activity
G7079_RS01890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7079_RS01900	COG0612	Peptidase, M16
G7079_RS01915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7079_RS01920	COG0596	Alpha beta hydrolase
G7079_RS01930	COG0727	PFAM Uncharacterised protein family (UPF0153)
G7079_RS01935	COG0318	PFAM AMP-dependent synthetase and ligase
G7079_RS01940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7079_RS01955	COG1064	alcohol dehydrogenase
G7079_RS01960	COG0612	Peptidase, M16
G7079_RS01965	COG0564	pseudouridine synthase activity
G7079_RS01990	COG1216	Glycosyl transferase, family 2
G7079_RS02030	COG0583	DNA-binding transcription factor activity
G7079_RS02035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G7079_RS02040	COG2224	Isocitrate lyase
G7079_RS02045	COG3706	GGDEF domain
G7079_RS02065	COG0606	chelatase, subunit chli
G7079_RS02090	COG1166	arginine decarboxylase activity
G7079_RS02100	COG4221	oxidoreductase activity
G7079_RS02135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7079_RS02155	COG2807	transmembrane transport
G7079_RS02165	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G7079_RS02170	COG0739	heme binding
G7079_RS02180	COG0187	DNA topoisomerase II activity
G7079_RS02265	COG0776	regulation of translation
G7079_RS02285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G7079_RS02290	COG4942	peptidase
G7079_RS02295	COG0793	Belongs to the peptidase S41A family
G7079_RS02315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7079_RS02320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G7079_RS02330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G7079_RS02355	COG1612	heme a metabolic process
G7079_RS02360	COG0109	protoheme IX farnesyltransferase activity
G7079_RS02365	COG3145	DNA-N1-methyladenine dioxygenase activity
G7079_RS02370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7079_RS02370	COG2169	Transcriptional regulator
G7079_RS02375	COG4946	Tricorn protease homolog
G7079_RS02375	COG0823	Involved in the tonB-independent uptake of proteins
G7079_RS02375	COG1506	peptidase
G7079_RS02380	COG0358	DNA primase activity
G7079_RS02400	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7079_RS02405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G7079_RS02410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7079_RS02435	COG0617	tRNA 3'-terminal CCA addition
G7079_RS02440	COG0741	lytic transglycosylase activity
G7079_RS02445	COG0730	response to heat
G7079_RS02465	COG2863	cytochrome
G7079_RS02475	COG0366	Alpha amylase catalytic
G7079_RS02480	COG3572	ergothioneine biosynthetic process
G7079_RS02490	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G7079_RS02510	COG1307	EDD domain protein, DegV family
G7079_RS02520	COG0804	urea catabolic process
G7079_RS02540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7079_RS02555	COG0436	Aminotransferase
G7079_RS02560	COG1162	GTPase activity
G7079_RS02570	COG0280	phosphate acetyltransferase
G7079_RS02570	COG0281	malic enzyme
G7079_RS02600	COG2818	Glycosylase
G7079_RS02610	COG2814	Major facilitator Superfamily
G7079_RS02630	COG2972	Histidine kinase
G7079_RS02645	COG3795	YCII-related domain
G7079_RS02650	COG3795	YCII-related domain
G7079_RS02665	COG4941	Belongs to the sigma-70 factor family
G7079_RS02695	COG2813	Specifically methylates the guanine in position
G7079_RS02700	COG1187	pseudouridine synthase activity
G7079_RS02705	COG2885	chlorophyll binding
G7079_RS02705	COG3047	cAMP biosynthetic process
G7079_RS02715	COG1666	GTP binding
G7079_RS02720	COG0697	spore germination
G7079_RS02740	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7079_RS02745	COG1196	nuclear chromosome segregation
G7079_RS02745	COG3264	Mechanosensitive ion channel
G7079_RS02750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7079_RS02760	COG0356	it plays a direct role in the translocation of protons across the membrane
G7079_RS02770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7079_RS02790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7079_RS02795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7079_RS02810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7079_RS02815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G7079_RS02895	COG0577	efflux transmembrane transporter activity
G7079_RS02895	COG1136	(ABC) transporter
G7079_RS02985	COG4206	TonB-dependent receptor
G7079_RS02995	COG1956	GAF domain-containing protein
G7079_RS03005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G7079_RS03010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_RS03015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_RS03035	COG0720	synthase
G7079_RS03090	COG1002	Type II restriction enzyme, methylase subunits
G7079_RS03100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G7079_RS03110	COG1278	Cold shock
G7079_RS03115	COG0564	pseudouridine synthase activity
G7079_RS03120	COG3654	unkown
G7079_RS03135	COG3384	dioxygenase
G7079_RS03145	COG4181	ATPase activity
G7079_RS03155	COG0151	Belongs to the GarS family
G7079_RS03165	COG0138	bifunctional purine biosynthesis protein purh
G7079_RS03170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G7079_RS03180	COG2264	protein methyltransferase activity
G7079_RS03190	COG0439	Biotin carboxylase
G7079_RS03195	COG0511	ligase activity, forming carbon-carbon bonds
G7079_RS03200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7079_RS03205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7079_RS03210	COG4232	protein-disulfide reductase activity
G7079_RS03215	COG1324	tolerance protein
G7079_RS03240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7079_RS03250	COG0778	Nitroreductase
G7079_RS03255	COG2353	YceI-like domain
G7079_RS03260	COG1741	Belongs to the pirin family
G7079_RS03285	COG1560	Kdo2-lipid A biosynthetic process
G7079_RS03290	COG1519	Transferase
G7079_RS03295	COG1538	Outer membrane efflux protein
G7079_RS03300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7079_RS03305	COG1309	transcriptional regulator
G7079_RS03320	COG0473	3-isopropylmalate dehydrogenase activity
G7079_RS03335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7079_RS03360	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7079_RS03370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G7079_RS03385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7079_RS03390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G7079_RS03400	COG1872	DUF167
G7079_RS03420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7079_RS03430	COG0671	phosphoesterase, PA-phosphatase related
G7079_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS03440	COG1595	DNA-templated transcription, initiation
G7079_RS03455	COG0346	lactoylglutathione lyase activity
G7079_RS03460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7079_RS03470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_RS03475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G7079_RS03485	COG1773	rubredoxin
G7079_RS03520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7079_RS03540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7079_RS03570	COG0006	proline dipeptidase activity
G7079_RS03575	COG0006	proline dipeptidase activity
G7079_RS03590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7079_RS03595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7079_RS03600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G7079_RS03605	COG1561	YicC-like family, N-terminal region
G7079_RS03620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7079_RS03630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7079_RS03645	COG0372	Belongs to the citrate synthase family
G7079_RS03660	COG0745	RESPONSE REGULATOR receiver
G7079_RS03665	COG2205	protein histidine kinase activity
G7079_RS03675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G7079_RS03705	COG0714	Associated with various cellular activities
G7079_RS03735	COG1301	dicarboxylic acid transport
G7079_RS03740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G7079_RS03745	COG0427	acetyl-CoA hydrolase
G7079_RS03750	COG3682	Transcriptional regulator
G7079_RS03790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7079_RS03800	COG4251	negative regulation of phosphorylation
G7079_RS03800	COG5001	Diguanylate cyclase
G7079_RS03800	COG3706	GGDEF domain
G7079_RS03800	COG2203	Gaf domain
G7079_RS03820	COG0469	pyruvate kinase activity
G7079_RS03825	COG3588	fructose-bisphosphate aldolase
G7079_RS03840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7079_RS03855	COG1970	mechanosensitive ion channel activity
G7079_RS03875	COG0471	metal ion transport
G7079_RS03875	COG3273	potassium ion transport
G7079_RS03885	COG2022	thiamine diphosphate biosynthetic process
G7079_RS03905	COG0189	ligase activity
G7079_RS03905	COG4067	protein conserved in archaea
G7079_RS03910	COG0189	ligase activity
G7079_RS03915	COG0745	RESPONSE REGULATOR receiver
G7079_RS03920	COG0642	Histidine kinase
G7079_RS03925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7079_RS03935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G7079_RS03940	COG4251	negative regulation of phosphorylation
G7079_RS03940	COG3706	GGDEF domain
G7079_RS03940	COG2203	Gaf domain
G7079_RS03940	COG5001	Diguanylate cyclase
G7079_RS03945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G7079_RS03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7079_RS03970	COG3422	double-strand break repair
G7079_RS03975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7079_RS03980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7079_RS03990	COG2119	membrane
G7079_RS03995	COG0667	Aldo Keto reductase
G7079_RS04015	COG1595	DNA-templated transcription, initiation
G7079_RS04020	COG0330	HflC and HflK could
G7079_RS04035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7079_RS04040	COG0509	glycine decarboxylation via glycine cleavage system
G7079_RS04060	COG1704	LemA family
G7079_RS04065	COG0501	Belongs to the peptidase M48B family
G7079_RS04100	COG3759	membrane
G7079_RS04110	COG1960	acyl-CoA dehydrogenase activity
G7079_RS04120	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G7079_RS04160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7079_RS04165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7079_RS04170	COG0463	Glycosyl transferase, family 2
G7079_RS04175	COG3620	sequence-specific DNA binding
G7079_RS04175	COG0617	tRNA 3'-terminal CCA addition
G7079_RS04175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7079_RS04180	COG1272	protein, Hemolysin III
G7079_RS04185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7079_RS04195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7079_RS04200	COG0626	cystathionine gamma-synthase activity
G7079_RS04205	COG0460	homoserine dehydrogenase
G7079_RS04205	COG0527	aspartate kinase activity
G7079_RS04210	COG5002	protein histidine kinase activity
G7079_RS04210	COG5001	Diguanylate cyclase
G7079_RS04215	COG1760	l-serine dehydratase
G7079_RS04230	COG3038	cytochrome b561
G7079_RS04235	COG2353	YceI-like domain
G7079_RS04245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7079_RS04270	COG0259	pyridoxamine-phosphate oxidase activity
G7079_RS04275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7079_RS04310	COG1678	Uncharacterized ACR, COG1678
G7079_RS04315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7079_RS04325	COG2239	Acts as a magnesium transporter
G7079_RS04330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7079_RS04335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7079_RS04345	COG1660	Displays ATPase and GTPase activities
G7079_RS04365	COG1137	ATPase activity
G7079_RS04380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G7079_RS04390	COG0271	Belongs to the BolA IbaG family
G7079_RS04410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7079_RS04415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7079_RS04425	COG0628	permease
G7079_RS04435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G7079_RS04440	COG3178	'Phosphotransferase
G7079_RS04455	COG1648	precorrin-2 dehydrogenase activity
G7079_RS04455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7079_RS04460	COG0583	DNA-binding transcription factor activity
G7079_RS04465	COG0175	sulfate reduction
G7079_RS04470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7079_RS04475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7079_RS04480	COG2261	transglycosylase associated protein
G7079_RS04505	COG4774	siderophore transport
G7079_RS04510	COG2146	nitrite reductase [NAD(P)H] activity
G7079_RS04515	COG0456	acetyltransferase
G7079_RS04520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7079_RS04525	COG0719	Fe-S assembly protein
G7079_RS04530	COG0396	ATPase activity
G7079_RS04535	COG0719	Fe-S assembly protein
G7079_RS04540	COG1959	2 iron, 2 sulfur cluster binding
G7079_RS04575	COG0739	heme binding
G7079_RS04585	COG1764	response to oxidative stress
G7079_RS04595	COG0384	phenazine biosynthesis protein PhzF
G7079_RS04605	COG0527	aspartate kinase activity
G7079_RS04615	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7079_RS04625	COG0142	geranyltranstransferase activity
G7079_RS04670	COG1073	alpha beta
G7079_RS04705	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G7079_RS04720	COG1946	Acyl-CoA thioesterase
G7079_RS04735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7079_RS04735	COG0116	Belongs to the methyltransferase superfamily
G7079_RS04740	COG3963	phosphatidate phosphatase activity
G7079_RS04745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7079_RS04760	COG1960	acyl-CoA dehydrogenase activity
G7079_RS04785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G7079_RS04790	COG1194	a g-specific adenine glycosylase
G7079_RS04800	COG0552	protein localization to endoplasmic reticulum
G7079_RS04805	COG0742	ribosomal rna small subunit methyltransferase
G7079_RS04820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7079_RS04830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7079_RS04835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7079_RS04850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G7079_RS04855	COG0343	queuine tRNA-ribosyltransferase activity
G7079_RS04860	COG1862	Preprotein translocase
G7079_RS04865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7079_RS04870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7079_RS04900	COG1253	flavin adenine dinucleotide binding
G7079_RS04910	COG0306	phosphate transporter
G7079_RS04935	COG3104	oligopeptide transport
G7079_RS04940	COG1297	OPT oligopeptide transporter protein
G7079_RS04945	COG0823	Involved in the tonB-independent uptake of proteins
G7079_RS04945	COG1506	peptidase
G7079_RS04965	COG4535	Mg2 and Co2 transporter CorC
G7079_RS04970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7079_RS04975	COG1702	phosphate starvation-inducible protein PhoH
G7079_RS04980	COG1309	transcriptional regulator
G7079_RS04990	COG1131	(ABC) transporter
G7079_RS04995	COG0842	Transport permease protein
G7079_RS05010	COG0741	lytic transglycosylase activity
G7079_RS05015	COG0723	plastoquinol--plastocyanin reductase activity
G7079_RS05020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7079_RS05025	COG2857	Cytochrome c1
G7079_RS05030	COG0625	glutathione transferase activity
G7079_RS05035	COG2969	positive regulation of protein catabolic process
G7079_RS05055	COG2835	tetraacyldisaccharide 4'-kinase activity
G7079_RS05080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7079_RS05090	COG2095	MarC family integral membrane protein
G7079_RS05100	COG1611	Belongs to the LOG family
G7079_RS05105	COG3275	phosphorelay sensor kinase activity
G7079_RS05110	COG4969	Belongs to the N-Me-Phe pilin family
G7079_RS05175	COG2207	Transcriptional regulator
G7079_RS05185	COG1741	Belongs to the pirin family
G7079_RS05195	COG0243	molybdopterin cofactor binding
G7079_RS05200	COG3781	membrane
G7079_RS05215	COG2837	iron assimilation
G7079_RS05220	COG0484	heat shock protein binding
G7079_RS05245	COG2826	transposase and inactivated derivatives, IS30 family
G7079_RS05290	COG2826	transposase and inactivated derivatives, IS30 family
G7079_RS05320	COG0582	viral genome integration into host DNA
G7079_RS05335	COG0556	nucleotide-excision repair
G7079_RS05340	COG1652	LysM domain
G7079_RS05370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7079_RS05380	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7079_RS05385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7079_RS05415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7079_RS05420	COG3590	peptidase
G7079_RS05430	COG0612	Peptidase, M16
G7079_RS05435	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
G7079_RS05455	COG0513	Belongs to the DEAD box helicase family
G7079_RS05460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G7079_RS05480	COG3118	belongs to the thioredoxin family
G7079_RS05520	COG0495	leucyl-tRNA aminoacylation
G7079_RS05535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7079_RS05555	COG2968	Membrane
G7079_RS05560	COG0424	maF-like protein
G7079_RS05565	COG1530	ribonuclease E activity
G7079_RS05575	COG0312	modulator of DNA gyrase
G7079_RS05585	COG0312	modulator of DNA gyrase
G7079_RS05600	COG0142	geranyltranstransferase activity
G7079_RS05610	COG0037	tRNA processing
G7079_RS05635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_RS05640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_RS05645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7079_RS05650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_RS05660	COG0750	zinc metalloprotease
G7079_RS05665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G7079_RS05670	COG0575	Belongs to the CDS family
G7079_RS05675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7079_RS05700	COG0052	Belongs to the universal ribosomal protein uS2 family
G7079_RS05705	COG0024	Methionine aminopeptidase
G7079_RS05720	COG1393	Belongs to the ArsC family
G7079_RS05725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7079_RS05730	COG0367	asparagine synthase
G7079_RS05735	COG0500	methyltransferase
G7079_RS05780	COG2010	Cytochrome c
G7079_RS05795	COG3278	Belongs to the heme-copper respiratory oxidase family
G7079_RS05830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7079_RS05880	COG4772	TonB-dependent receptor
G7079_RS05890	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G7079_RS05905	COG0288	reversible hydration of carbon dioxide
G7079_RS05920	COG0277	FAD linked oxidase domain protein
G7079_RS05925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7079_RS05930	COG2181	nitrate reductase activity
G7079_RS05935	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G7079_RS05940	COG1140	nitrate reductase beta subunit
G7079_RS05945	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G7079_RS05955	COG0314	molybdopterin synthase activity
G7079_RS05965	COG0303	'Molybdopterin
G7079_RS05970	COG0315	cyclic pyranopterin monophosphate synthase activity
G7079_RS05970	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7079_RS05975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7079_RS05990	COG0557	exoribonuclease II activity
G7079_RS05995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7079_RS06010	COG3220	belongs to the UPF0276 family
G7079_RS06020	COG0704	Plays a role in the regulation of phosphate uptake
G7079_RS06030	COG0581	inorganic phosphate transmembrane transporter activity
G7079_RS06035	COG0573	inorganic phosphate transmembrane transporter activity
G7079_RS06040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G7079_RS06055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7079_RS06065	COG1024	Enoyl-CoA hydratase
G7079_RS06100	COG0824	Thioesterase
G7079_RS06105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7079_RS06115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7079_RS06120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7079_RS06135	COG0196	riboflavin kinase activity
G7079_RS06150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7079_RS06180	COG2814	Major facilitator Superfamily
G7079_RS06185	COG1566	PFAM secretion protein HlyD family protein
G7079_RS06190	COG1538	Outer membrane efflux protein
G7079_RS06195	COG1846	Transcriptional regulator
G7079_RS06205	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7079_RS06210	COG0228	four-way junction DNA binding
G7079_RS06215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7079_RS06220	COG0336	Belongs to the RNA methyltransferase TrmD family
G7079_RS06240	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7079_RS06250	COG2378	regulation of single-species biofilm formation
G7079_RS06270	COG4771	TonB-dependent receptor
G7079_RS06275	COG1546	Belongs to the CinA family
G7079_RS06280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7079_RS06285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7079_RS06290	COG2137	regulation of response to DNA damage stimulus
G7079_RS06295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7079_RS06300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G7079_RS06330	COG0366	Alpha amylase catalytic
G7079_RS06340	COG1082	Xylose isomerase domain protein TIM barrel
G7079_RS06345	COG2382	esterase
G7079_RS06355	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7079_RS06360	COG0800	Aldolase
G7079_RS06365	COG0837	glucose binding
G7079_RS06380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G7079_RS06400	COG0351	phosphomethylpyrimidine kinase
G7079_RS06400	COG0352	thiamine-phosphate diphosphorylase activity
G7079_RS06410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7079_RS06415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7079_RS06425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7079_RS06435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G7079_RS06445	COG0617	tRNA 3'-terminal CCA addition
G7079_RS06455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G7079_RS06460	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7079_RS06465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G7079_RS06470	COG0166	Belongs to the GPI family
G7079_RS06475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G7079_RS06480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7079_RS06480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7079_RS06485	COG0802	atpase or kinase
G7079_RS06490	COG0860	N-Acetylmuramoyl-L-alanine amidase
G7079_RS06495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7079_RS06510	COG2878	Part of a membrane complex involved in electron transport
G7079_RS06515	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_RS06515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_RS06530	COG0489	protein tyrosine kinase activity
G7079_RS06535	COG0717	Belongs to the dCTP deaminase family
G7079_RS06580	COG0412	Dienelactone hydrolase
G7079_RS06585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7079_RS06590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7079_RS06595	COG3015	lipoprotein NlpE involved in copper resistance
G7079_RS06600	COG0433	COG0433 Predicted ATPase
G7079_RS06610	COG0688	phosphatidylethanolamine metabolic process
G7079_RS06615	COG1999	signal sequence binding
G7079_RS06620	COG2890	protein-(glutamine-N5) methyltransferase activity
G7079_RS06630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7079_RS06640	COG0101	tRNA pseudouridine synthase activity
G7079_RS06650	COG0133	tryptophan synthase activity
G7079_RS06665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7079_RS06670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7079_RS06685	COG0149	triose-phosphate isomerase activity
G7079_RS06725	COG0625	glutathione transferase activity
G7079_RS06730	COG3104	oligopeptide transport
G7079_RS06745	COG1187	pseudouridine synthase activity
G7079_RS06760	COG1201	RNA secondary structure unwinding
G7079_RS06765	COG0339	signal peptide processing
G7079_RS06770	COG0386	Belongs to the glutathione peroxidase family
G7079_RS06795	COG2133	pyrroloquinoline quinone binding
G7079_RS06825	COG4104	PAAR repeat-containing protein
G7079_RS06835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7079_RS06840	COG0084	hydrolase, TatD family'
G7079_RS06855	COG1960	acyl-CoA dehydrogenase activity
G7079_RS06860	COG0625	glutathione transferase activity
G7079_RS06865	COG0022	dehydrogenase e1 component
G7079_RS06875	COG0354	folic acid binding
G7079_RS06890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G7079_RS06915	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7079_RS06930	COG0811	peptide transport
G7079_RS06940	COG1132	(ABC) transporter
G7079_RS06945	COG1663	tetraacyldisaccharide 4'-kinase activity
G7079_RS06955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G7079_RS06960	COG0322	excinuclease ABC activity
G7079_RS06965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7079_RS06985	COG0069	glutamate synthase activity
G7079_RS06995	COG0529	Catalyzes the synthesis of activated sulfate
G7079_RS06995	COG2895	sulfate adenylyltransferase (ATP) activity
G7079_RS07010	COG0489	protein tyrosine kinase activity
G7079_RS07015	COG0484	heat shock protein binding
G7079_RS07040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G7079_RS07045	COG2244	polysaccharide biosynthetic process
G7079_RS07065	COG0438	transferase activity, transferring glycosyl groups
G7079_RS07075	COG0438	transferase activity, transferring glycosyl groups
G7079_RS07080	COG0438	transferase activity, transferring glycosyl groups
G7079_RS07090	COG1086	Polysaccharide biosynthesis protein
G7079_RS07095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7079_RS07125	COG0535	radical SAM domain protein
G7079_RS07160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G7079_RS07185	COG1132	(ABC) transporter
G7079_RS07190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7079_RS07215	COG4221	oxidoreductase activity
G7079_RS07250	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G7079_RS07255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7079_RS07265	COG0077	Prephenate dehydratase
G7079_RS07265	COG1605	Chorismate mutase
G7079_RS07270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7079_RS07275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7079_RS07305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7079_RS07330	COG1595	DNA-templated transcription, initiation
G7079_RS07345	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7079_RS07365	COG2197	response regulator
G7079_RS07370	COG1530	ribonuclease E activity
G7079_RS07385	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7079_RS07390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G7079_RS07390	COG0316	Belongs to the HesB IscA family
G7079_RS07420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_RS07450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_RS07455	COG2957	Belongs to the agmatine deiminase family
G7079_RS07465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7079_RS07470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G7079_RS07480	COG0776	regulation of translation
G7079_RS07490	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G7079_RS07505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7079_RS07510	COG0183	Belongs to the thiolase family
G7079_RS07515	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7079_RS07515	COG1024	Enoyl-CoA hydratase
G7079_RS07525	COG0105	UTP biosynthetic process
G7079_RS07530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7079_RS07540	COG1426	Protein conserved in bacteria
G7079_RS07550	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_RS07555	COG1160	GTP binding
G7079_RS07560	COG0746	molybdenum cofactor guanylyltransferase activity
G7079_RS07565	COG0303	'Molybdopterin
G7079_RS07570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7079_RS07590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7079_RS07600	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_RS07600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_RS07605	COG1309	transcriptional regulator
G7079_RS07610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_RS07640	COG3706	GGDEF domain
G7079_RS07645	COG0668	transmembrane transport
G7079_RS07660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G7079_RS07705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7079_RS07710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7079_RS07725	COG1674	ftsk spoiiie
G7079_RS07730	COG0492	ferredoxin-NADP+ reductase activity
G7079_RS07740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G7079_RS07750	COG0542	response to heat
G7079_RS07755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7079_RS07765	COG0482	sulfurtransferase activity
G7079_RS07770	COG2915	High frequency lysogenization protein hflD homolog
G7079_RS07775	COG2409	Drug exporters of the RND superfamily
G7079_RS07780	COG2826	transposase and inactivated derivatives, IS30 family
G7079_RS07800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G7079_RS07815	COG1024	Enoyl-CoA hydratase
G7079_RS07820	COG2205	protein histidine kinase activity
G7079_RS07820	COG2198	Histidine kinase
G7079_RS07820	COG0784	Response regulator, receiver
G7079_RS07845	COG4676	Protein conserved in bacteria
G7079_RS07850	COG3279	Response regulator of the LytR AlgR family
G7079_RS07860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7079_RS07870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7079_RS07875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7079_RS07880	COG0505	Belongs to the CarA family
G7079_RS07885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7079_RS07900	COG0443	Heat shock 70 kDa protein
G7079_RS07905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7079_RS07910	COG1420	regulation of RNA biosynthetic process
G7079_RS07920	COG0735	belongs to the Fur family
G7079_RS07925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_RS07930	COG2914	Belongs to the UPF0125 (RnfH) family
G7079_RS07935	COG2867	negative regulation of translational initiation
G7079_RS07945	COG2205	protein histidine kinase activity
G7079_RS07945	COG2202	Pas domain
G7079_RS07975	COG0305	Participates in initiation and elongation during chromosome replication
G7079_RS07985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7079_RS07990	COG0360	Binds together with S18 to 16S ribosomal RNA
G7079_RS08000	COG0017	Asparaginyl-tRNA synthetase
G7079_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS08025	COG0288	reversible hydration of carbon dioxide
G7079_RS08050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_RS08055	COG2925	Exonuclease
G7079_RS08075	COG2902	Dehydrogenase
G7079_RS08080	COG1960	acyl-CoA dehydrogenase activity
G7079_RS08095	COG0646	methionine synthase
G7079_RS08095	COG1410	methionine synthase
G7079_RS08100	COG2814	Major facilitator Superfamily
G7079_RS08110	COG2900	Belongs to the SlyX family
G7079_RS08130	COG0386	Belongs to the glutathione peroxidase family
G7079_RS08140	COG1725	Transcriptional regulator
G7079_RS08145	COG1131	(ABC) transporter
G7079_RS08185	COG2850	peptidyl-arginine hydroxylation
G7079_RS08190	COG2153	protein acetylation
G7079_RS08195	COG0567	Dehydrogenase, E1 component
G7079_RS08210	COG0387	Pfam Sodium calcium exchanger
G7079_RS08220	COG0604	alcohol dehydrogenase
G7079_RS08235	COG0678	peroxiredoxin activity
G7079_RS08260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7079_RS08265	COG3115	cell septum assembly
G7079_RS08280	COG2350	Protein conserved in bacteria
G7079_RS08295	COG1187	pseudouridine synthase activity
G7079_RS08330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_RS08335	COG0436	Aminotransferase
G7079_RS08340	COG4133	protoheme IX ABC transporter activity
G7079_RS08350	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
G7079_RS08380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7079_RS08405	COG3088	subunit of a heme lyase
G7079_RS08405	COG4235	cytochrome complex assembly
G7079_RS08415	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G7079_RS08435	COG3243	poly(R)-hydroxyalkanoic acid synthase
G7079_RS08445	COG1183	phosphatidylcholine synthase activity
G7079_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS08465	COG2205	protein histidine kinase activity
G7079_RS08465	COG0784	Response regulator, receiver
G7079_RS08475	COG2610	gluconate transmembrane transporter activity
G7079_RS08485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7079_RS08495	COG0477	Major facilitator Superfamily
G7079_RS08500	COG2183	response to ionizing radiation
G7079_RS08505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7079_RS08505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7079_RS08520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7079_RS08530	COG1185	polyribonucleotide nucleotidyltransferase activity
G7079_RS08535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7079_RS08555	COG0195	Participates in both transcription termination and antitermination
G7079_RS08560	COG0779	Required for maturation of 30S ribosomal subunits
G7079_RS08570	COG1007	ATP synthesis coupled electron transport
G7079_RS08600	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7079_RS08605	COG1034	ATP synthesis coupled electron transport
G7079_RS08615	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G7079_RS08620	COG0649	NAD binding
G7079_RS08630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7079_RS08635	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7079_RS08645	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7079_RS08660	COG0519	Catalyzes the synthesis of GMP from XMP
G7079_RS08660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7079_RS08665	COG2081	HI0933 family
G7079_RS08705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7079_RS08710	COG3706	GGDEF domain
G7079_RS08715	COG2199	diguanylate cyclase activity
G7079_RS08715	COG2203	Gaf domain
G7079_RS08760	COG0251	oxidation-reduction process
G7079_RS08775	COG3038	cytochrome b561
G7079_RS08795	COG0204	Acyl-transferase
G7079_RS08800	COG3706	GGDEF domain
G7079_RS08810	COG3706	GGDEF domain
G7079_RS08815	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7079_RS08825	COG5001	Diguanylate cyclase
G7079_RS08825	COG4251	negative regulation of phosphorylation
G7079_RS08825	COG3706	GGDEF domain
G7079_RS08825	COG2203	Gaf domain
G7079_RS08850	COG0625	glutathione transferase activity
G7079_RS08860	COG1901	pseudouridine methyltransferase
G7079_RS08890	COG3220	belongs to the UPF0276 family
G7079_RS08920	COG2944	sequence-specific DNA binding
G7079_RS08930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7079_RS08930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G7079_RS08930	COG1703	isobutyryl-CoA mutase activity
G7079_RS08935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7079_RS08955	COG1960	acyl-CoA dehydrogenase activity
G7079_RS08965	COG0183	Belongs to the thiolase family
G7079_RS08980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7079_RS09015	COG1024	Enoyl-CoA hydratase
G7079_RS09020	COG2957	Belongs to the agmatine deiminase family
G7079_RS09060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7079_RS09070	COG0277	FAD linked oxidase domain protein
G7079_RS09075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7079_RS09085	COG0531	amino acid
G7079_RS09090	COG0235	Class ii aldolase
G7079_RS09095	COG0235	Class ii aldolase
G7079_RS09105	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
G7079_RS09115	COG5001	Diguanylate cyclase
G7079_RS09115	COG3300	MHYT domain
G7079_RS09120	COG2986	histidine ammonia-lyase
G7079_RS09125	COG0124	histidyl-tRNA synthetase
G7079_RS09135	COG0784	Response regulator, receiver
G7079_RS09135	COG2198	Histidine kinase
G7079_RS09135	COG5002	protein histidine kinase activity
G7079_RS09140	COG4797	methyltransferase
G7079_RS09140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7079_RS09230	COG3501	Rhs element vgr protein
G7079_RS09255	COG2885	chlorophyll binding
G7079_RS09265	COG3210	domain, Protein
G7079_RS09280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7079_RS09285	COG0165	Argininosuccinate lyase
G7079_RS09290	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7079_RS09295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7079_RS09300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7079_RS09305	COG0137	argininosuccinate synthase activity
G7079_RS09310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7079_RS09345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7079_RS09355	COG1469	GTP cyclohydrolase I activity
G7079_RS09375	COG0402	S-adenosylhomocysteine deaminase activity
G7079_RS09385	COG1509	lysine 2,3-aminomutase activity
G7079_RS09390	COG5001	Diguanylate cyclase
G7079_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS09410	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G7079_RS09415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7079_RS09415	COG0140	phosphoribosyl-ATP diphosphatase activity
G7079_RS09420	COG0107	imidazoleglycerol-phosphate synthase activity
G7079_RS09425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7079_RS09435	COG0131	Imidazoleglycerol-phosphate dehydratase
G7079_RS09435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7079_RS09440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7079_RS09445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7079_RS09450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7079_RS09480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
G7079_RS09495	COG4948	Mandelate Racemase Muconate Lactonizing
G7079_RS09505	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G7079_RS09510	COG0460	homoserine dehydrogenase
G7079_RS09510	COG0527	aspartate kinase activity
G7079_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
G7079_RS09550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7079_RS09555	COG0697	spore germination
G7079_RS09560	COG0671	phosphoesterase, PA-phosphatase related
G7079_RS09565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7079_RS09575	COG1012	belongs to the aldehyde dehydrogenase family
G7079_RS09580	COG5001	Diguanylate cyclase
G7079_RS09585	COG1595	DNA-templated transcription, initiation
G7079_RS09595	COG1132	(ABC) transporter
G7079_RS09600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7079_RS09610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_RS09615	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G7079_RS09625	COG1472	Belongs to the glycosyl hydrolase 3 family
G7079_RS09630	COG2954	triphosphatase activity
G7079_RS09635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7079_RS09655	COG1381	Involved in DNA repair and RecF pathway recombination
G7079_RS09675	COG0681	Belongs to the peptidase S26 family
G7079_RS09685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7079_RS09700	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7079_RS09700	COG1024	Enoyl-CoA hydratase
G7079_RS09715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7079_RS09720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7079_RS09725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7079_RS09730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7079_RS09735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7079_RS09745	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS09750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G7079_RS09755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7079_RS09760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7079_RS09765	COG1399	metal-binding, possibly nucleic acid-binding protein
G7079_RS09785	COG0714	Associated with various cellular activities
G7079_RS09805	COG0537	adenosine 5'-monophosphoramidase activity
G7079_RS09815	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7079_RS09820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7079_RS09855	COG0314	molybdopterin synthase activity
G7079_RS09880	COG3642	lipopolysaccharide core region biosynthetic process
G7079_RS09885	COG0859	PFAM glycosyl transferase family 9
G7079_RS09905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7079_RS09960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7079_RS09965	COG0740	serine-type endopeptidase activity
G7079_RS09970	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7079_RS10010	COG0473	3-isopropylmalate dehydrogenase activity
G7079_RS10025	COG4783	chaperone-mediated protein folding
G7079_RS10030	COG0745	RESPONSE REGULATOR receiver
G7079_RS10040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7079_RS10065	COG1131	(ABC) transporter
G7079_RS10070	COG1725	Transcriptional regulator
G7079_RS10075	COG0438	transferase activity, transferring glycosyl groups
G7079_RS10080	COG0671	phosphoesterase, PA-phosphatase related
G7079_RS10100	COG4452	Inner membrane protein CreD
G7079_RS10105	COG2205	protein histidine kinase activity
G7079_RS10110	COG0745	RESPONSE REGULATOR receiver
G7079_RS10115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G7079_RS10125	COG2354	Protein conserved in bacteria
G7079_RS10135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7079_RS10140	COG1515	deoxyribonuclease V activity
G7079_RS10195	COG0431	NADPH-dependent FMN reductase
G7079_RS10205	COG0431	NADPH-dependent FMN reductase
G7079_RS10350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G7079_RS10360	COG2197	response regulator
G7079_RS10365	COG4585	Histidine kinase
G7079_RS10380	COG2894	cell division
G7079_RS10385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G7079_RS10395	COG3511	phospholipase C
G7079_RS10410	COG0531	amino acid
G7079_RS10430	COG0515	serine threonine protein kinase
G7079_RS10430	COG2815	serine threonine protein kinase
G7079_RS10435	COG3850	Histidine kinase
G7079_RS10440	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7079_RS10440	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7079_RS10450	COG0308	aminopeptidase N
G7079_RS10470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7079_RS10480	COG0330	HflC and HflK could
G7079_RS10485	COG0330	HflC and HflK could
G7079_RS10490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7079_RS10495	COG1923	regulation of RNA biosynthetic process
G7079_RS10500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7079_RS10505	COG0531	amino acid
G7079_RS10520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G7079_RS10525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G7079_RS10530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G7079_RS10535	COG1534	Rna-binding protein
G7079_RS10550	COG1238	metal cluster binding
G7079_RS10560	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7079_RS10575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G7079_RS10585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G7079_RS10590	COG0148	phosphopyruvate hydratase activity
G7079_RS10595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G7079_RS10630	COG0791	NLP P60 protein
G7079_RS10635	COG0791	NLP P60 protein
G7079_RS10655	COG1301	dicarboxylic acid transport
G7079_RS10660	COG1785	Belongs to the alkaline phosphatase family
G7079_RS10730	COG4771	TonB-dependent receptor
G7079_RS10735	COG0457	Tetratricopeptide repeat
G7079_RS10775	COG3070	regulator of competence-specific genes
G7079_RS10785	COG3267	Type II secretory pathway component ExeA
G7079_RS10785	COG3409	Peptidoglycan-binding domain 1 protein
G7079_RS10840	COG5507	3-demethylubiquinone-9 3-methyltransferase
G7079_RS10850	COG0513	Belongs to the DEAD box helicase family
G7079_RS10870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7079_RS10895	COG0243	molybdopterin cofactor binding
G7079_RS10915	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G7079_RS10935	COG1228	amidohydrolase
G7079_RS10965	COG3746	phosphate-selective porin O and P
G7079_RS10975	COG0735	belongs to the Fur family
G7079_RS10980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7079_RS10985	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7079_RS10995	COG2833	Protein of unknown function (DUF455)
G7079_RS11010	COG0285	dihydrofolate synthase activity
G7079_RS11015	COG0406	alpha-ribazole phosphatase activity
G7079_RS11040	COG0156	8-amino-7-oxononanoate synthase activity
G7079_RS11060	COG1902	pentaerythritol trinitrate reductase activity
G7079_RS11060	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7079_RS11070	COG0625	glutathione transferase activity
G7079_RS11090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7079_RS11100	COG0039	L-malate dehydrogenase activity
G7079_RS11135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7079_RS11155	COG0154	amidase activity
G7079_RS11160	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G7079_RS11165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G7079_RS11170	COG0203	ribosomal protein L17
G7079_RS11180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7079_RS11195	COG0201	protein transport
G7079_RS11205	COG1841	ribosomal large subunit assembly
G7079_RS11210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7079_RS11215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7079_RS11225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7079_RS11235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7079_RS11240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7079_RS11245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7079_RS11250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7079_RS11255	COG0255	Belongs to the universal ribosomal protein uL29 family
G7079_RS11260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7079_RS11265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7079_RS11270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7079_RS11275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7079_RS11280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7079_RS11285	COG0089	rRNA binding
G7079_RS11290	COG0088	Forms part of the polypeptide exit tunnel
G7079_RS11295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7079_RS11300	COG0051	transcription antitermination factor activity, RNA binding
G7079_RS11305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7079_RS11315	COG0049	tRNA binding
G7079_RS11320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7079_RS11325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7079_RS11335	COG0222	ribosome binding
G7079_RS11350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7079_RS11355	COG0250	Participates in transcription elongation, termination and antitermination
G7079_RS11360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7079_RS11370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7079_RS11390	COG0012	GTP binding
G7079_RS11395	COG0193	aminoacyl-tRNA hydrolase activity
G7079_RS11405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7079_RS11430	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7079_RS11435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7079_RS11440	COG0456	acetyltransferase
G7079_RS11445	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7079_RS11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7079_RS11470	COG1295	ribonuclease BN
G7079_RS11485	COG0457	Tetratricopeptide repeat
G7079_RS11490	COG0252	asparaginase activity
G7079_RS11495	COG3227	Zinc metalloprotease (Elastase)
G7079_RS11550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7079_RS11550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7079_RS11580	COG3634	alkyl hydroperoxide reductase activity
G7079_RS11585	COG0583	DNA-binding transcription factor activity
G7079_RS11610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7079_RS11625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_RS11630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7079_RS11640	COG2096	Adenosyltransferase
G7079_RS11645	COG0123	including yeast histone deacetylase and acetoin utilization protein
G7079_RS11650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G7079_RS11655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7079_RS11660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G7079_RS11665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7079_RS11675	COG2967	ApaG domain
G7079_RS11680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7079_RS11685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_RS11700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7079_RS11710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G7079_RS11715	COG1704	LemA family
G7079_RS11720	COG0861	Integral membrane protein TerC family
G7079_RS11725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7079_RS11730	COG0577	efflux transmembrane transporter activity
G7079_RS11730	COG1136	(ABC) transporter
G7079_RS11735	COG1136	(ABC) transporter
G7079_RS11735	COG0577	efflux transmembrane transporter activity
G7079_RS11740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_RS11745	COG0642	Histidine kinase
G7079_RS11765	COG3956	TIGRFAM MazG family protein
G7079_RS11770	COG1218	3'(2'),5'-bisphosphate nucleotidase
G7079_RS11775	COG0494	nUDIX hydrolase
G7079_RS11785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7079_RS11800	COG2198	Histidine kinase
G7079_RS11800	COG0643	Histidine kinase
G7079_RS11805	COG0840	transmembrane signaling receptor activity
G7079_RS11825	COG0189	ligase activity
G7079_RS11850	COG1199	ATP-dependent helicase activity
G7079_RS11855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7079_RS11860	COG0438	transferase activity, transferring glycosyl groups
G7079_RS11860	COG1216	Glycosyl transferase, family 2
G7079_RS11865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7079_RS11870	COG1643	Atp-dependent helicase
G7079_RS11875	COG0783	Belongs to the Dps family
G7079_RS11895	COG0514	ATP-dependent DNA helicase (RecQ)
G7079_RS11905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G7079_RS11910	COG0602	queuosine metabolic process
G7079_RS11920	COG2885	chlorophyll binding
G7079_RS11945	COG0824	Thioesterase
G7079_RS11950	COG2255	four-way junction helicase activity
G7079_RS11960	COG0632	four-way junction helicase activity
G7079_RS11965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7079_RS11995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7079_RS12000	COG3706	GGDEF domain
G7079_RS12015	COG0488	(ABC) transporter
G7079_RS12020	COG4651	solute:proton antiporter activity
G7079_RS12020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7079_RS12025	COG0542	response to heat
G7079_RS12050	COG0564	pseudouridine synthase activity
G7079_RS12055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7079_RS12065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7079_RS12065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7079_RS12075	COG0045	succinate-CoA ligase (ADP-forming) activity
G7079_RS12105	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G7079_RS12110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7079_RS12115	COG2244	polysaccharide biosynthetic process
G7079_RS12120	COG2226	methyltransferase
G7079_RS12130	COG1216	Glycosyl transferase, family 2
G7079_RS12145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7079_RS12150	COG2226	methyltransferase
G7079_RS12160	COG1215	transferase activity, transferring glycosyl groups
G7079_RS12175	COG0438	transferase activity, transferring glycosyl groups
G7079_RS12180	COG0463	Glycosyl transferase, family 2
G7079_RS12195	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7079_RS12205	COG0494	nUDIX hydrolase
G7079_RS12210	COG0653	protein targeting
G7079_RS12215	COG0739	heme binding
G7079_RS12225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G7079_RS12240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7079_RS12245	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7079_RS12250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7079_RS12270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7079_RS12285	COG3116	cell division
G7079_RS12290	COG0275	rRNA processing
G7079_RS12295	COG2001	Belongs to the MraZ family
G7079_RS12310	COG1446	asparaginase
G7079_RS12325	COG0792	nuclease activity
G7079_RS12335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7079_RS12340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7079_RS12355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7079_RS12355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7079_RS12360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7079_RS12365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7079_RS12370	COG0583	DNA-binding transcription factor activity
G7079_RS12380	COG0488	(ABC) transporter
G7079_RS12385	COG0284	orotidine-5'-phosphate decarboxylase activity
G7079_RS12400	COG1450	Type ii and iii secretion system protein
G7079_RS12415	COG3166	PFAM Fimbrial assembly family protein
G7079_RS12420	COG3156	type II secretion system protein K
G7079_RS12425	COG4795	General secretion pathway protein
G7079_RS12430	COG2165	general secretion pathway protein
G7079_RS12435	COG4970	Tfp pilus assembly protein FimT
G7079_RS12440	COG2165	general secretion pathway protein
G7079_RS12445	COG1459	type II secretion system
G7079_RS12450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7079_RS12455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7079_RS12455	COG0047	phosphoribosylformylglycinamidine synthase activity
G7079_RS12460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7079_RS12465	COG4974	Belongs to the 'phage' integrase family
G7079_RS12475	COG0795	lipopolysaccharide-transporting ATPase activity
G7079_RS12485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7079_RS12510	COG1183	phosphatidylcholine synthase activity
G7079_RS12525	COG0442	prolyl-tRNA aminoacylation
G7079_RS12540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7079_RS12545	COG1127	ABC transporter
G7079_RS12580	COG2086	electron transfer activity
G7079_RS12590	COG0463	Glycosyl transferase, family 2
G7079_RS12605	COG1028	Short-chain dehydrogenase reductase Sdr
G7079_RS12610	COG0318	PFAM AMP-dependent synthetase and ligase
G7079_RS12625	COG2076	Multidrug Resistance protein
G7079_RS12630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7079_RS12645	COG0438	transferase activity, transferring glycosyl groups
G7079_RS12645	COG1216	Glycosyl transferase, family 2
G7079_RS12665	COG0626	cystathionine gamma-synthase activity
G7079_RS12680	COG2885	chlorophyll binding
G7079_RS12690	COG0625	glutathione transferase activity
G7079_RS12715	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7079_RS12735	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G7079_RS12740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7079_RS12760	COG0134	indole-3-glycerol-phosphate synthase activity
G7079_RS12765	COG2329	Antibiotic biosynthesis monooxygenase
G7079_RS12770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7079_RS12770	COG0189	ligase activity
G7079_RS12775	COG0189	ligase activity
G7079_RS12775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G7079_RS12785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G7079_RS12790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7079_RS12805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7079_RS12810	COG1597	lipid kinase activity
G7079_RS12825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7079_RS12840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7079_RS12855	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G7079_RS12870	COG0673	inositol 2-dehydrogenase activity
G7079_RS12875	COG0457	Tetratricopeptide repeat
G7079_RS12885	COG1501	Belongs to the glycosyl hydrolase 31 family
G7079_RS12890	COG2222	sugar isomerase
G7079_RS12895	COG1940	carbohydrate kinase activity
G7079_RS12905	COG1349	DNA-binding transcription factor activity
G7079_RS12915	COG2814	Major facilitator Superfamily
G7079_RS12920	COG3104	oligopeptide transport
G7079_RS12925	COG3483	tryptophan 2,3-dioxygenase activity
G7079_RS12970	COG0180	Tryptophanyl-tRNA synthetase
G7079_RS13010	COG4208	sulfate ABC transporter
G7079_RS13015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7079_RS13025	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G7079_RS13030	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G7079_RS13030	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G7079_RS13035	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G7079_RS13040	COG1461	Dihydroxyacetone kinase
G7079_RS13050	COG3228	Belongs to the MtfA family
G7079_RS13055	COG2205	protein histidine kinase activity
G7079_RS13060	COG0745	RESPONSE REGULATOR receiver
G7079_RS13075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7079_RS13090	COG0456	acetyltransferase
G7079_RS13090	COG0454	-acetyltransferase
G7079_RS13125	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7079_RS13130	COG1522	sequence-specific DNA binding
G7079_RS13135	COG0686	Belongs to the AlaDH PNT family
G7079_RS13140	COG2267	carboxylic ester hydrolase activity
G7079_RS13145	COG2824	Alkylphosphonate utilization operon protein PhnA
G7079_RS13155	COG3189	MarR family transcriptional regulator
G7079_RS13160	COG0702	epimerase
G7079_RS13185	COG1741	Belongs to the pirin family
G7079_RS13220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7079_RS13240	COG0628	permease
G7079_RS13245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7079_RS13250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7079_RS13260	COG2197	response regulator
G7079_RS13265	COG4585	Histidine kinase
G7079_RS13275	COG1131	(ABC) transporter
G7079_RS13280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7079_RS13285	COG1136	(ABC) transporter
G7079_RS13290	COG0577	efflux transmembrane transporter activity
G7079_RS13295	COG0577	efflux transmembrane transporter activity
G7079_RS13305	COG0697	spore germination
G7079_RS13310	COG1522	sequence-specific DNA binding